MERRILL LYNCH SERIES FUND INC
497J, 1996-05-03
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                  MERRILL LYNCH SERIES FUND, INC.



                                    May 3, 1996


VIA ELECTRONIC FILING
_____________________

Securities and Exchange Commission
450 Fifth Street, N.W.
Judiciary Plaza
Washington, D.C. 20549

Attention:  Division of Investment Management

      Re:   Merrill Lynch Series Fund, Inc.
            Post-Effective Amendment No. 18 to the
            Registration Statement on Form N-1A
            (Securities Act File No. 2-69062)


Ladies and Gentlemen:

            Pursuant  to  Rule  497(j) under the Securities Act of 1933, as
amended (the "1933 Act"), Merrill  Lynch  Series  Fund,  Inc.  (the "Fund")
hereby certifies that:

            (1)   the  form  of  the prospectus and statement of additional
information that would have been filed  pursuant  to  Rule 497(b) under the
1933  Act  would  not  have differed from that contained in  Post-Effective
Amendment  No.  18 to the  Fund's  Registration  Statement  on  Form  N-1A,
constituting the most recent amendment to the Fund's Registration Statement
on Form N-1A; and

            (2)   the text of Post-Effective Amendment No. 18 to the Fund's
Registration Statement  on  Form  N-1A  was  filed  electronically with the
Securities and Exchange Commission on April 29, 1996.


                              Very truly yours,

                              Merrill Lynch Series Fund, Inc.

                              /s/ Ira P. Shapiro
                              -------------------------------
                              Ira P. Shapiro
                              Secretary





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