MERRILL LYNCH SERIES FUND INC
497, 1999-05-05
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                         MERRILL LYNCH SERIES FUND, INC.

                          Supplement Dated May 5, 1999
                     to the Prospectus Dated April 21, 1999


Page  3 of  the  Prospectus  for  Merrill  Lynch  Intermediate  Government  Bond
Portfolio is amended by deleting the paragraphs headed "What are the Portfolio's
goals?" and "What are the Portfolio's main investment strategies?" and replacing
them with the following:

WHAT ARE THE PORTFOLIO'S GOALS?

The Portfolio tries to provide current income from an actively managed portfolio
of U.S. government and agency securities. We cannot guarantee that the Portfolio
will achieve its goals.

WHAT ARE THE PORTFOLIO'S MAIN INVESTMENT STRATEGIES?

The  Portfolio  invests  in bonds and other debt  securities  that are issued or
guaranteed   by  the   U.S.   government   or  U.S.   government   AGENCIES   or
GOVERNMENT-SPONSORED  ENTERPRISES.  The  Portfolio  may  invest   a  substantial
portion   of   its   assets   in    MORTGAGE-BACKED   SECURITIES    issued   by
government-sponsored  enterprises.  The  Portfolio may also invest in securities
linked  to an  interest  rate or  other  index.  The  Portfolio  may  invest  in
securities  of any  MATURITY,  but under normal  circumstances  will  maintain a
dollar-weighted average maturity of six to eight years.

Page  7 of  the  Prospectus  for  Merrill  Lynch  Intermediate  Government  Bond
Portfolio is amended by deleting the second  paragraph and replacing it with the
following:

The  Portfolio   may  invest  in  securities  of  any  maturity.   Under  normal
circumstances,  however,  the Portfolio will maintain a dollar-weighted  average
maturity of six to eight years.





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