INTERNATIONAL REMOTE IMAGING SYSTEMS INC /DE/
NT 10-K, 1997-04-01
LABORATORY ANALYTICAL INSTRUMENTS
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                        UNITED STATES               
             SECURITIES AND EXCHANGE COMMISSION 
                   Washington, D.C.  20549 
      
                         FORM 12b-25

                 NOTIFICATION OF LATE FILING

                                           Commission File Number    1-9767
                                                                  ------------

(Check One):  
[X] Form 10-K   [ ] Form 20-F  [ ] Form 11-K  [ ] Form 10-Q  [ ] Form N-SAR

    For Period Ended:                   December 31, 1996
                      --------------------------------------------------------

[ ] Transition Report on Form 10-K
[ ] Transition Report on Form 20-F
[ ] Transition Report on Form 11-K
[ ] Transition Report on Form 10-Q
[ ] Transition Report on Form N-SAR

    For the Transition Period Ended:
                                     -----------------------------------------

- ------------------------------------------------------------------------------
    Nothing in this form shall be construed to imply that the Commission has
                   verified any information contained herein.
- ------------------------------------------------------------------------------

If the notification relates to a portion of the filing checked above, identify
the Item(s) to which the notification relates:

- ------------------------------------------------------------------------------


                       PART I -- REGISTRANT INFORMATION

                   International Remote Imaging Systems, Inc.
- ------------------------------------------------------------------------------
Full Name of Registrant


- ------------------------------------------------------------------------------
Former Name if Applicable

                                9162 Eton Avenue
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Address of Principal Executive Office (Street and Number)


                              Chatsworth, CA 91311
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City, State and Zip Code

                       PART II--RULES 12b-25(b) AND (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rules 12b-25(b), the following
should be completed.  (Check box if appropriate)

         [X]              (a)     The reasons described in reasonable detail in
                                  Part III of this form could not be eliminated
                                  without unreasonable effort or expense;

         [X]              (b)     The subject annual report, semi-annual
                                  report, transition report on Form 10-K, Form
                                  20-F, 11-K, Form N-SAR, or portion thereof,
                                  will be filed on or before the fifteenth
                                  calendar day following the prescribed due
                                  date; or the subject quarterly report of
                                  transition report on Form 10-Q, or portion
                                  thereof will be filed on or before the fifth
                                  calendar day following the prescribed due
                                  date; and

         [ ]              (c)     The accountant's statement or other exhibit
                                  required by Rule 12b-25(c) has been attached 
                                  if applicable.
<PAGE>   2
                             PART III--NARRATIVE

State below in reasonable detail the reasons why the Form 10-K, 20-F, 11-K,
10-Q, N-SAR, or the transition report or portion thereof, could not be filed
within the prescribed time period.  (ATTACH EXTRA SHEETS IF NEEDED)

        The Registrant is unable to file its 1996 Annual Report on Form 10-K
within the prescribed period of time because of the unusual effort required to
obtain and integrate for the first time annual operational and other
information from globally-dispersed locations in California, Texas,
Massachusetts and the United Kingdom. Prior to the acquisitions made during
1996, the registrant's operations were limited to a single location in
California. 

                          PART IV--OTHER INFORMATION

(1)              Name and telephone number of person to contact in regard to
                 this notification

<TABLE>
                  <S>                                       <C>              <C>
                         Martin S. McDermut                    (818)              709-1244
                 ---------------------------------------    -----------      ------------------
                             (Name)                         (Area Code)      (Telephone Number)
</TABLE>

(2)              Have all other periodic reports required under Section 13 or
                 15(d) of the Securities Exchange Act of 1934 or Section 30 of
                 the Investment Company Act of 1940 during the preceding 12
                 months or for such shorter period that the registrant was
                 required to file such report(s) been filed?  If answer is no,
                 identify report(s).

                                                                 [X] Yes [ ] No
                 ------------------------------------------------

(3)              Is it anticipated that any significant change in results of
                 operations from the corresponding period for the last fiscal
                 year will be reflected by the earnings statements to be
                 included in the subject report of portion thereof?

                                                                 [X] Yes [ ] No

                 If so, attach an explanation of the anticipated change, both
                 narratively and quantitatively, and, if appropriate, state the
                 reasons why a reasonable estimate of the results cannot be
                 made.

                              (See "Attachments")
- ------------------------------------------------------------------------------
                   International Remote Imaging Systems, Inc.
                  --------------------------------------------
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized.

Date       April 1, 1997               By  /s/ Martin S. McDermut     
     ---------------------------         -------------------------------------
                                         Martin S. McDermut, Vice President
                                         Finance and Administration and
                                         Chief Financial Officer
                                         

INSTRUCTION:  The form may be signed by an executive officer of the registrant
or by any other duly authorized representative.  The name and title of the
person signing the form shall be typed or printed beneath the signature.  If
the statement is signed on behalf of the registrant by an authorized
representative (other than an executive officer), evidence of the
representative's authority to sign on behalf of the registrant shall be filed
with the form.


                                   ATTENTION

- ------------------------------------------------------------------------------
   Intentional misstatements or omissions of fact constitute Federal Criminal
                        Violations (See 18 U.S.C. 1001)
- ------------------------------------------------------------------------------





                                               (Attach Extra Sheets If Needed)
<PAGE>   3

                   INTERNATIONAL REMOTE IMAGING SYSTEMS, INC.

                           Attachments to Form 12b-25


Date:  April 1, 1997    Commission File Number:  1-9767


PART IV - OTHER INFORMATION

        Net sales for the year ended December 31, 1996 increased to $20.6 
million from $14.4 million, an increase of $6.2 million or 43% over the prior 
year. Pending completion of its annual audit, the Company expects to report a
pretax loss of $10.9 million for the year ended December 31, 1996, as compared
to a pretax loss of $1.5 million for the year ended December 31, 1995. The 
increase in the loss is due primarily to acquisition-related expenses and 
certain non-recurring charges. The Company has not yet determined its 
provision (benefit) for income taxes for 1996.

        The pretax loss for 1996 is largely attributable to $7.3 million of 
acquisition expenses for the purchase of the PowerGene genetic analyzer 
business from Perceptive Scientific Instruments, Inc. and $2.0 million of 
nonrecurring charges, primarily for the write-off of deferred offering costs, 
litigation expenses, restructuring charges and merger expenses. The pretax 
loss for 1996 also includes $800,000 for amortization of goodwill and other 
intangibles and $700,000 of interest expense resulting primarily from debt 
financing for the acquisition. The pretax loss for 1995 is largely 
attributable to $2.9 million of acquisition expenses for the purchase of 
in-process research and development for The White IRIS leukocyte differential 
analyzer from LDA Systems, Inc. The pretax loss for 1995 also includes 
$127,000 for amortization of intangibles and $43,000 of interest expense.

        Excluding these items, the Company would have had a pretax loss of 
approximately $100,000 for the year ended December 31, 1996, as compared to a
pretax profit of approximately $1.6 million for the year ended December 31, 
1995.

        The results of operations reported herein include (i) the results of 
operations of StatSpin, Inc. for all of 1995 and 1996 in accordance with the 
pooling-of-interests method of accounting and (ii) only five months of 
operation of the business acquired from Perceptive Scientific Instruments, Inc.
in accordance with the purchase method of accounting. The Company acquired 
StatSpin, Inc. in February 1996 and the business of Perceptive Scientific 
Instruments, Inc. in July 1996.

        The information reported herein is subject to the final results of the
Company's annual audit currently in progress.



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