PHARMAKINETICS LABORATORIES INC
SC 13D, 1997-11-13
TESTING LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934

                        PharmaKinetics Laboratories, Inc.
- --------------------------------------------------------------------------------

                                (Name of Issuer)

                    Common Stock, Par Value $0.001 Per Share

- --------------------------------------------------------------------------------

                         (Title of Class of Securities)

                                   717131 10 6
                         -----------------------------

                                 (CUSIP Number)

                                Leslie B. Daniels
                               CAI Advisors & Co.
                           767 Fifth Avenue, 5th Floor
                               New York, NY 10153
                                 (212) 319-2525
- --------------------------------------------------------------------------------

       (Name, Address and Telephone Number of Persons Authorized to 
                  Receive Notices and Communications)

                                November 3, 1997
                          ----------------------------

             (Date of Event which Requires Filing of this Statement)


If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box [ ].

Check the following box if a fee is being paid with this statement.| | (A fee is
not required only if the reporting person:  (1) has a previous statement on file
reporting  beneficial  ownership  of more  than  five  percent  of the  class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7.)

Note: Six copies of this statement, including all exhibits, should be filed with
the Commission. See Rule 13d-1(a) for other parties to whom copies are to be 
sent.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



                                                         1

<PAGE>



                                  SCHEDULE 13D

CUSIP No.


      1  NAME OF REPORTING PERSON
         S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

         CAI Advisors & Co.
      2  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*          (a) X
                                                                    (b) |_|
      3  SEC USE ONLY
      4  SOURCE OF FUNDS*
           WC
      5  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
         PURSUANT TO ITEMS 2(d) OR 2(e)                                 |_|
      6  CITIZENSHIP OR PLACE OF ORGANIZATION
           Quebec, Canada
                                                           7 SOLE VOTING POWER
                                                             0
                      NUMBER OF
                       SHARES
                    BENEFICIALLY
                    OWNED BY EACH
                     REPORTING
                    PERSON WITH

                                                   8  SHARED VOTING POWER
                                                      2,750,000
                                                   9  SOLE DISPOSITIVE POWER
                                                      0**
                                                  10  SHARED DISPOSITIVE POWER
                                                      2,750,000**
     11  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         2,750,000**
     12  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                                |_|
     13  PERCENT OF CLASS REPRESENTED
         BY AMOUNT IN ROW (11)
         18.4**
     14  TYPE OF REPORTING PERSON*
         PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT

                  **SEE DESCRIPTION PRESENTED UNDER THE CAPTION
                 "ITEM 5. INTEREST IN SECURITIES OF THE ISSUER"

                                                         2

<PAGE>



                                  SCHEDULE 13D

CUSIP No.


      1  NAME OF REPORTING PERSON
         S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

         Aster-Cephac
      2  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a) X
                                                                     (b) |_|
      3  SEC USE ONLY
      4  SOURCE OF FUNDS*
          WC
      5  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
         PURSUANT TO ITEMS 2(d) or 2(e)                                  |_|
      6  CITIZENSHIP OR PLACE OF ORGANIZATION
         France
                                                           7 SOLE VOTING POWER
                                                             0
                      NUMBER OF
                       SHARES
                    BENEFICIALLY
                    OWNED BY EACH
                     REPORTING
                    PERSON WITH

                                                   8  SHARED VOTING POWER
                                                      2,750,000
                                                   9  SOLE DISPOSITIVE POWER
                                                      0**
                                                  10  SHARED DISPOSITIVE POWER
                                                      2,750,000**
     11  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         2,750,000**
     12  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                                   |_|
     13  PERCENT OF CLASS REPRESENTED
         BY AMOUNT IN ROW (11)
         18.4**
     14  TYPE OF REPORTING PERSON*
         CO

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                  **SEE DESCRIPTION PRESENTED UNDER THE CAPTION
                 "ITEM 5. INTEREST IN SECURITIES OF THE ISSUER"

                                                         3

<PAGE>




Item 1.  Security and Issuer.

         This  Statement  relates to 2,750,000  shares of the common stock,  par
value $0.001 per share (the "Common  Stock"),  of  PharmaKinetics  Laboratories,
Inc., a Maryland corporation (the "Company").  The Company's principal executive
offices are located at 302 West Fayette Street, Baltimore, Maryland 21201.

Item 2. Identity and Background.

        Pursuant to Rule  13d-1(f) of  Regulation  13D of the General  Rules and
Regulations  under  the  Securities  Exchange  Act of  1934  (the  "Act"),  this
Statement  is  being  filed  by CAI  Advisors  & Co.  ("CAI")  and  Aster-Cephac
("Aster").  The foregoing entities are hereinafter referred to as the "Reporting
Persons." The Reporting  Persons are making this single joint filing pursuant to
Rule 13d-1(f)(1).

         CAI is a partnership  organized under the laws of Quebec, Canada having
its principal  executive  offices  located at 767 Fifth Avenue,  5th Floor,  New
York,  NY  10153.  CAI  and  its  affiliates  are  investment  funds  that  make
investments in the contract research  organization,  pharmaceutical  and related
industries. A list of the managing partners of CAI is attached as Schedule 1.

         Aster is a French corporation,  affiliated with CAI, with its principal
executive  offices  located at 3 et 5 rue Eugene  Millon,  75015 Paris,  France.
Aster is a contract research organization serving the pharmaceutical industry. A
list of the executive officers and directors of Aster is attached as Schedule 2.

         During the last five years,  neither  Reporting Person nor any partner,
executive  officer or director of either Reporting  Person,  to the knowledge of
either Reporting Person, has been convicted in a criminal proceeding  (excluding
traffic  violations  or  similar  misdemeanors)  or has  been a party to a civil
proceeding of a judicial or administrative body of competent jurisdiction and as
a result of such  proceeding  was or is subject to a  judgment,  decree or final
order  enjoining  future  violations of, or prohibiting or mandating  activities
subject  to,  federal or state  securities  laws or finding any  violation  with
respect to such laws.

         The information with respect to a particular Reporting Person contained
in this  Schedule  13D is given  solely by such  Reporting  Person and the other
Reporting  Person has no  responsibility  for the  accuracy or  completeness  of
information supplied by such Reporting Person.

Item 3. Source and Amount of Funds or Other Consideration.

         The source of funds used to purchase the Common Stock would  consist of
working  capital  of the  Reporting  Persons.  The amount of funds  required  to
purchase the Common Stock,  or the aggregate  exercise  price of the  Contingent
Warrants described in Item 4, would be $1.65 million.

Item 4. Purpose of Transaction.

         The  purpose of the  acquisition  of  securities  of the Company by the
Reporting  Persons is for investment  and to facilitate a strategic  partnership
between  Aster and the  Company.  Except as  discussed  in this Item 4,  neither
Reporting  Person  currently  has any plan or proposal that relates to, or would
result  in,  any of the  actions  enumerated  in Item 4 of the  instructions  to
Schedule 13D.

                                                         4

<PAGE>



         On October 24, 1997, the Company entered into an agreement in principle
(the "Agreement") with the Reporting  Persons.  The Agreement  contemplates that
the Company will sell to the Reporting Persons and their assigns Preferred Stock
convertible into 8,333,000 shares of Common Stock (the "Shares") and warrants to
purchase  6,250,000  shares of Common  Stock at an  exercise  price of $1.20 per
share (the  "Warrants")  for an  aggregate  purchase  price of $5  million.  The
Agreement further contemplates that the Reporting Persons will have the right to
representation  on the  Company's  Board of  Directors.  In the  event  that the
Company fails to consummate  the sale of the Shares and Warrants by December 31,
1997 (or such later date as may be agreed upon by the  parties),  the  Agreement
provides that the Company will issue to the Reporting Persons, for no additional
consideration,  warrants  to  purchase  2,750,000  shares of Common  Stock at an
exercise price of $.60 per share (the "Contingent Warrants").

         The purpose of this  Schedule  13D is to disclose  the  interest of the
Reporting  Persons  in the  2,750,000  shares of  Common  Stock  underlying  the
Contingent  Warrants.  The  Reporting  Persons  will file an  amendment  to this
Schedule 13D following execution of a definitive  agreement relating to the sale
of the Shares and the Warrants.  Assuming consummation of the sale of the Shares
and the Warrants,  the Reporting Persons would acquire  beneficial  ownership of
approximately 41% of the Company's voting  securities  assuming the Warrants are
not exercised,  or approximately 54% of the Company's voting securities assuming
the Warrants are exercised.

Item 5. Interest in Securities of the Company.

         In  accordance  with Rules  13d-3(d)(1)(i)  and  13d-5(b)(1)  under the
Securities  Act of 1933,  as  amended,  each of CAI and  Aster  may be deemed to
beneficially  own 2,750,000  shares of Common  Stock,  or 18.4% of the Company's
outstanding  Common Stock. CAI and Aster would share voting and investment power
with respect to all of such shares.

         Neither Reporting Person nor any partner, executive officer or director
of either Reporting  Person,  to the knowledge of either Reporting  Person,  had
purchased any of the Company's securities during the past sixty days.

Item 6. Contracts, Arrangements, Understandings or Relationships with Respect to
Securities of the Company.

         None except as disclosed in Item 4.

Item 7. Material to be Filed as Exhibits.

        The Letter of Intent between the Reporting  Persons and the Company will
be filed by amendment to this Schedule 13D.




                                                         5

<PAGE>



                                   Signatures

         After  reasonable  inquiry and to the best of his knowledge and belief,
each of the  undersigned  certifies  that  the  information  set  forth  in this
Statement is true, complete and correct.


Date:  November 13, 1996


                                        CAI ADVISORS & CO.

                                          /S/ LESLIE B. DANIELS

                                        By:
                                               Name:  Leslie B. Daniels
                                               Title: Partner


                                        ASTER-CEPHAC

                                           /S/ LESLIE B. DANIELS
                                        By:
                                               Name:  Leslie B. Daniels
                                               Title: Director


                                                         6

<PAGE>



                                   SCHEDULE 1


                     MANAGING PARTNERS OF CAI ADVISORS & CO.



NAME                                ADDRESS                          CITIZENSHIP

Mr. Richard J. Schmeelk             CAI Advisors & Co.                   U.S.
                                    767 Fifth Avenue, 5th Floor
                                    New York, NY  10153

Mr. Peter M. Gottsegen              CAI Advisors & Co.                   U.S.
                                    767 Fifth Avenue, 5th Floor
                                    New York, NY  10153

Mr. Leslie B. Daniels               CAI Advisors & Co.                   U.S.
                                    767 Fifth Avenue, 5th Floor
                                    New York, NY  10153

Mr. Peter G. Restler                CAI Advisors & Co.                   U.S.
                                    767 Fifth Avenue, 5th Floor
                                    New York, NY  10153


                                                         7

<PAGE>


                                   SCHEDULE 2


               DIRECTORS AND EXECUTIVE OFFICERS OF ASTER o CEPHAC


NAME                                 ADDRESS                        CITIZENSHIP

Mr. Jean Jacques Thebault            Aster o  Cephac                   French
                                     3 et 5 rue Eugene Millon
                                     75015 Paris France

Mr. David M. Culver                  CAI Capital Corporation           Canadian
                                     3429 Drummon Street
                                     Suite 200
                                     Montreal, Quebec H3G 1X6

Mr. Leslie B. Daniels                CAI Advisors & Co.                  U.S.
                                     767 Fifth Avenue, 5th Floor
                                     New York, NY  10153

Mr. David von Kauffmann              CAI Capital Corporation            French
                                     46 rue Paul Valery
                                     75016 Paris France

Mr. Jean Francois                    Aster o  Cephac                    French
                                     3 et 5 rue Eugene Millon
                                     75015 Paris France

                                                         8



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