PHARMAKINETICS LABORATORIES INC
S-8, 2000-02-25
TESTING LABORATORIES
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                                       Registration No. 333-____________________
As filed with the Securities and Exchange Commission on February 24, 2000.
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                        PHARMAKINETICS LABORATORIES, INC.
             (Exact Name of Registrant as Specified in its Charter)

         MARYLAND                                          52-1067519
  (State of Incorporation)                     (IRS Employer Identification No.)

                             302 WEST FAYETTE STREET
                            BALTIMORE, MARYLAND 21201
                    (Address of Principal Executive Offices)

                        PHARMAKINETICS LABORATORIES, INC.
                        1996 INCENTIVE STOCK OPTION PLAN
                            (Full Title of the Plan)

<TABLE>
<CAPTION>
<S>     <C>    <C>    <C>    <C>    <C>    <C>
                                                                     Copies to:
James M. Wilkinson, II, Ph.D.                                        Melissa Allison Warren, Esquire
President and Chief Executive Officer                                Ober, Kaler, Grimes & Shriver
302 West Fayette Street                                              120 East Baltimore Street
Baltimore, Maryland  21201                                           Baltimore, Maryland 21202
(410) 385-4500                                                       (410) 347-7684
(Name, Address and Telephone Number of Agent for Service)
- --------------------------------------------------------------------------------------------------------------------
                                         CALCULATION OF REGISTRATION FEE
- --------------------------------------------------------------------------------------------------------------------
                                                     Proposed              Proposed
  Title of                                           Maximum               Maximum
 Securities               Amount                     Offering              Aggregate                Amount of
   to be                  to be                       Price                Offering               Registration
 Registered            Registered(1)                Per Share(2)             Price                     Fee
- --------------------------------------------------------------------------------------------------------------------
Common Stock           150,000 shares                 $1.03125            $154,687.50                $264.00
</TABLE>

(1) Together with such indeterminate number of additional shares as may be
issuable to avoid dilution as the result of a stock split, stock dividend or
similar adjustment of the Common Stock pursuant to 17 C.F.R. Section 230.416(a).
(2) Estimated pursuant to Rule 457(h)(l) solely for the basis of calculating the
registration fee, based on the average of the high and low price as reported by
the OTC Bulletin Board on February 18, 2000.

             This Registration Statement shall become effective upon
                  filing in accordance with Section 8(a) of the
                       Securities Act of 1933, as amended.



<PAGE>

This registration statement is filed for the purpose of registering 150,000
additional shares of the common stock of PharmaKinetics Laboratories, Inc. for
issuance under the PharmaKinetics Laboratories, Inc. 1996 Incentive Stock Option
Plan. The registrant filed a registration statement on Form S-8 relating to that
stock option plan on January 15, 1997, registration no. 333-19865. The contents
of such earlier registration statement are incorporated herein by reference
pursuant to General Instruction E of Form S-8.

The opinion and consent of Ober, Kaler, Grimes & Shriver and the consent of
PricewaterhouseCoopers LLP are filed herewith as exhibits:

Exhibit 5         Opinion of Ober, Kaler, Grimes & Shriver as to the legality of
                  the Common Stock registered hereunder

Exhibit 23.1      Consent of Ober, Kaler, Grimes & Shriver (contained in the
                  opinion included as Exhibit 5).

Exhibit 23.2      Consent of PricewaterhouseCoopers LLP, Independent Accountants

                                       1

<PAGE>

                                   SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized in the City of Baltimore and the State of Maryland, this 23rd day of
February, 2000.


                                    PHARMAKINETICS LABORATORIES, INC.


                                       By: /s/ James M. Wilkinson, II
                                          ------------------------------
                                          James M. Wilkinson, II, Ph.D.
                                          President and Chief Executive Officer

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the date indicated:
<TABLE>
<CAPTION>
        Name                                                  Title                               Date
        ----                                                  -----                               ----
<S>     <C>    <C>    <C>    <C>    <C>    <C>
/s/ James M. Wilkinson, II                 President and Chief Executive Officer               February 23, 2000
- --------------------------                      (Principal Executive Officer)
James M. Wilkinson, II, Ph.D.                          and Director



/s/ Leslie B. Daniels                                       Director                           February  23, 2000
- ----------------------------------
Leslie B. Daniels


/s/ Thomas F. Kearns, Jr.                                   Director                           February 23, 2000
- ----------------------------------
Thomas F. Kearns. Jr.


/s/ Kamal Midha, Ph.D.                                      Director                           February 23, 2000
- ----------------------------------
Kamal Midha, Ph.D.


/s/ Roger C. Thies                                          Director                           February 23, 2000
- ----------------------------------
Roger C. Thies


/s/ Taryn L. Kunkel                                     Vice President                         February 23, 2000
- ---------------------------------                 (Principal Financial and
Taryn L. Kunkel                                       Accounting Officer)
</TABLE>


                                       2


<PAGE>

                                  EXHIBIT INDEX
                                  -------------



Exhibit
No.             Description
- ---             -----------
5               Opinion of Ober, Kaler, Grimes & Shriver
23.1            Consent of Ober, Kaler, Grimes & Shriver (contained
                within Exhibit 5 filed herewith)
23.2            Consent of PricewaterhouseCoopers  LLP,
                Independent Accountants


                                       3


                                                                       EXHIBIT 5


                                                               February 15, 2000

PharmaKinetics Laboratories, Inc.
302 West Fayette Street
Baltimore, Maryland  21201

                  Re:      PharmaKinetics  Laboratories,  Inc. 1996 Incentive
                           Stock Option Plan - Registration  Statement on Form
                           S-8 for 150,000  Additional  Shares of Common Stock

Ladies and Gentlemen:

         We have acted as counsel for PharmaKinetics Laboratories, Inc. (the
"Company") in connection with the registration under the Securities Act of 1933,
as amended, on Form S-8 of 150,000 shares of the Company's Common Stock, $.005
par value (the "Shares"), to be issued under the PharmaKinetics Laboratories,
Inc. 1996 Incentive Stock Option Plan (the "Incentive Option Plan"). As such
counsel, we have examined the Company's registration statement filed on Form S-8
on January 15, 1997, the Company's registration statement on Form S-8 to which
this opinion is an exhibit, the charter and bylaws of the Company, the Incentive
Option Plan and such corporate proceedings of the Company as we have deemed
appropriate, and we have made such other legal and factual examinations and
inquiries as we deemed advisable for the purpose of rendering this opinion.

         In such examination, we have assumed without independent verification
the genuineness of all signatures, the authenticity of all documents submitted
to us originals, the conformity to original documents of documents submitted to
us as certified or photostatic copies and the authenticity of the originals of
such latter documents. As to all questions of fact material to this opinion that
have not been independently established, we have relied upon certificate or
comparable documents of officers of the Company, and have relied upon the
accuracy and completeness of the relevant facts therein without independent
verification.

         Based on the foregoing and subject to the qualifications stated herein,
we are of the opinion that the Shares reserved for issuance under the Incentive
Option Plan have been duly and validly authorized and upon the issuance and
delivery of the Shares in the manner and for the consideration described under
the Incentive Option Plan, the Shares will be legally issued, fully paid and
nonassessable.

         We hereby consent to the filing of this opinion as an exhibit to the
Company's Registration Statement on Form S-8, and we consent to the use of our
name therein. In giving such consent, we do not hereby admit that we are in the
category of persons whose consent is required under Section 7 of the Securities
Act of 1933, as amended.

                                            Very truly yours,
                                            /s/ Ober, Kaler, Grimes & Shriver,
                                                a Professional Corporation




                                                                    EXHIBIT 23.2


                       CONSENT OF INDEPENDENT ACCOUNTANTS
                       ----------------------------------


We hereby consent to the incorporation by reference in this Registration
Statement on Form S-8 of our report dated August 13, 1999, except for the third
paragraph of Note G, as to which the date is September 13, 1999, relating to the
financial statements and financial statement schedules of PharmaKinetics
Laboratories, Inc., which appears in PharmaKinetics Laboratories, Inc.'s Annual
Report on Form 10-K for the year ended June 30, 1999.



PricewaterhouseCoopers LLP

Baltimore, Maryland
February 22, 2000




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