INTERFERON SCIENCES INC
424B2, 1997-09-15
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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PROSPECTUS SUPPLEMENT

                            Interferon Sciences, Inc.

                         858,479 Shares of Common Stock

         This Prospectus  Supplement  relates to 858,479 shares of Common Stock,
par value $.01 per share (the "Common Stock"), of Interferon  Sciences,  Inc., a
Delaware corporation (the "Company"), being offered by the Company.

         759,715  of such  shares of Common  Stock  are  being  offered  through
Sunrise Securities Corp. ("Sunrise") or Preferred Technology, Inc. (collectively
with Sunrise,  the "Agents"),  as agent. Each Agent will receive a placement fee
equal to 6%, and an  unaccountable  expense  allowance equal to 2%, of the gross
proceeds of the shares sold through such Agent hereunder.  If all of such shares
are sold,  the net proceeds to the Company,  after  payment of the placement fee
and expense allowance,  will be approximately  $4,456,000.  Each Agent will also
receive  options  (the "Agent  Options")  to purchase 5% of the number of shares
sold  through  such Agent  hereunder  at an exercise  price equal to 120% of the
offering price of the shares being sold through such Agent hereunder.  The Agent
Options will be exercisable for a period of four years,  commencing on the first
anniversary of the issue date,  and cannot be sold,  transferred,  assigned,  or
hypothecated  until such date, except that they may be assigned,  in whole or in
part,  to any  successor,  officer,  or partner of the  Agent.  This  Prospectus
Supplement  also relates to 60,777 shares being offered to the Agents at a price
equal to the  offering  price of the  shares  being  sold  through  such  Agents
hereunder  and  37,987  shares  underlying  the  Agent  Options.  Certain  prior
relationships  between  Sunrise and the Company are described in the  prospectus
under the caption "Selling Stockholders."

         The Common Stock is quoted on the NASDAQ  National  Market System under
the symbol  "IFSC." On September 5, 1997,  the last  reported  sale price of the
Common Stock on the NASDAQ National Market System was $8.875 per share.
                                                 ----------------


         INVESTMENT IN THE SHARES OFFERED HEREBY INVOLVES A HIGH DEGREE
          OF RISK. SEE "RISK FACTORS" ON PAGES 3-11 OF THIS PROSPECTUS.
                                                 ----------------

  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
       EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION, NOR HAS THE
      SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION
  PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION
                     TO THE CONTRARY IS A CRIMINAL OFFENSE.



           The date of this Prospectus Supplement is September 8, 1997




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