INTERFERON SCIENCES INC
10-K/A, 1998-04-30
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-K/A

/X/ Annual Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act
    of 1934

    For the Fiscal Year Ended  December 31, 1997

/ / Transition Report Pursuant to Section 13 or 15(d)of the Securities Exchange 
    Act of 1934

    For the transition Period from ________to________

                         Commission File Number 0-10379

                            INTERFERON SCIENCES, INC.
             (Exact name of registrant as specified in its charter)

Delaware                                                   22-2313648
(State or other jurisdiction of                            (I.R.S. Employer
incorporation or organization)                              Identification No.)

783 Jersey Avenue, New Brunswick, New Jersey               08901
(Address of principal executive offices)                   (Zip Code)

Registrant's telephone number, including area code:        (732) 249-3250

Securities registered pursuant to Section 12(b) of the Act:   None

Securities registered pursuant to Section 12(g) of the Act:

                     Common Stock, Par Value $0.01 Per Share
                                (Title of Class)

         Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the  Securities  Exchange  Act of
1934  during  the  preceding  12 months  (or for such  shorter  Period  that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the past 90 days.

                                 Yes X No ----

         Indicate by check mark if disclosure of delinquent  filers  pursuant to
Item 405 of Regulation S-K is not contained  herein,  and will not be contained,
to the best of  registrant's  knowledge,  in  definitive  proxy  or  information
statements  incorporated  by  reference  in Part  III of this  Form  10-K or any
amendment to this Form 10-K. / /

         As of April 9, 1998,  the  aggregate  market  value of the  outstanding
shares of the  registrant's  Common  Stock,  par value $.01 per  share,  held by
non-affiliates  (assuming  for  this  calculation  only  that all  officers  and
directors  are  affiliates)  was  approximately  $26,500,000  based  on the last
reported sale price of such stock on the NASDAQ  National Market System on April
9, 1998.

         Indicate the number of shares  outstanding of each of the  registrant's
classes of common stock, as of the latest practicable date.

         Class                               Outstanding at March 12 , 1998
         -----                               ------------------------------

Common Stock, par value $.01 per share       15,234,774 shares

                       DOCUMENTS INCORPORATED BY REFERENCE
None.


<PAGE>


      The Company's 10K for the year ended  December 31, 1997 is hereby  amended
by including Part III as follows:

                                    PART III

Item 10. Directors and Executive Officers of the Registrant

         Set forth below are the  officers  and  directors  of the Company as of
April 30, 1998.

       Martin M.  Pollak has been a Director  of the Company and a member of the
Executive  Committee  since  1981 and  Chairman  of the Board  from  1981  until
September  1996. He is a founder of G.P.  STRATEGIES,  Inc.  (formerly  National
Patent Development  corporation) ("NPDC"), which is primarily a holding company,
and has been Executive Vice President,  Treasurer,  and a director of NPDC since
1959.  Mr.  Pollak is Chief  Executive  Officer,  President  and a  director  of
American Drug Company  ("ADC"),  which provides  consulting  services to Western
companies doing business in Russia and Eastern  Europe.  He has been Chairman of
the Board of General  Physics  Corporation  ("GPC"),  and a director  from 1987;
Chairman of the Board and  director of SGLG,  since 1991;  and a director of GSE
Systems, Inc. ("GSE") since 1994. Mr. Pollak is the former Chairman of the Czech
and Slovak United States Economic Council, a trustee of the Board of Trustees of
the Worcester  Foundation for Experimental Biology and was a director of Brandon
Systems Corporation from 1986 to 1996. Age 70.

       Jerome I.  Feldman has been a Director of the Company and a member of the
Executive  Committee  since 1981,  Chairman of the  Executive  Committee  of the
Company from 1981 until  September 1996 and Treasurer from 1984 until  September
1996.  Mr.  Feldman is founder  of,  and since  1959 has been  President,  Chief
Executive  Officer,  and a director  of NPDC.  He has been been  Chairman of the
Executive Committee of GPC since 1988 and a director of GPC since 1987; Chairman
of the Executive  Committee and a Director of SGLG since 1991; and a director of
GSE  since  1994 and  Chairman  of the Board of GSE since  April  1997.  He is a
trustee of the New England Colleges Fund and of Bard College. Age 69.

       Samuel H. Ronel,  Ph.D. has been a Director of the Company since 1981 and
Chairman of the Board since  February  1997.  He was Vice  Chairman from January
1996 until  February 1997 and was President and Chief  Executive  Officer,  from
1981 to  January  1996.  He was  responsible  for the  interferon  research  and
development  program since its inception in 1979.  Dr. Ronel joined NPDC in 1970
and served as the Vice  President of Research and  Development of NPDC from 1976
to  September  1996 and as the  President of Hydro Med  Sciences,  a division of
NPDC,  from 1976 to September 1996. Dr. Ronel served as President of Association
of Biotechnology  Companies, an international  organization  representing United
States and foreign  biotechnology  firms,  from 1986 to 1988 and has served as a
member of the Board of Directors  until 1993. Dr. Ronel was elected to the Board
of Directors of the Biotechnology Industry Organization in 1993. Age 61.

       Lawrence M. Gordon has been Chief Executive Officer and a director of the
Company since January 1996,  Vice  President of the Company from 1991 to January
1996,  General Counsel of the Company since 1984,  General Counsel of NPDC since
1986,  and Vice  President of NPDC from 1991 to September  1996.  Mr. Gordon has
been a director of GPC since 1994. Age 44.

       Stanley G.  Schutzbank,  Ph.D.  has been  President of the Company  since
January 1996, Executive Vice President of the Company from 1981 to January 1996,
and a  director  of the  Company  since  1981 and has been  associated  with the
interferon  research and development  program since its inception in 1979. He is
involved with all facets of  administration  and planning of the Company and has
coordinated compliance with FDA regulations governing manufacturing and clinical
testing of  interferon,  leading to the approval of ALFERON N Injection in 1989.
Dr.  Schutzbank  joined  NPDC in 1972 and served as the  Corporate  Director  of
Regulatory and Clinical  Affairs of NPDC from 1976 until  September 1996, and as
Executive Vice President of Hydro Med Sciences from 1982 until  September  1996.
Dr. Schutzbank is a member of the Regulatory Affairs  Professionals  Society and
has  served as  Chairman  of the  Regulatory  Affairs  Certification  Board from
inception  until  1994.  Dr.  Schutzbank  received  the 1991  Richard  E.  Greco
Regulatory  Affairs  Professional  of the  Year  Award  for  his  leadership  in
developing the United States Regulatory Affairs Certification  Program. In 1995,
Dr.  Schutzbank was elected to serve as  President-elect  in 1996,  President in
1997, and Chairman of the Board in 1998 of the Regulatory Affairs  Professionals
Society. Age 52.

       Leon  Botstein,  Ph.D.  has been a  Director  of the  Company  since
1981 and has been  President  of Bard College, Annandale-on-Hudson, New York
since 1975. Age 51.

       Scott N. Greenberg has been a director of the Company since January 1996,
Vice President,  Chief Financial  Officer,  and a director of NPDC since 1989, a
director of GPC since 1987, a director of SGLG since 1991,  and Chief  Financial
Officer of ADC since 1994. Age 41.

       Roald  Hoffmann,  Ph.D.  has been a director of the Company  since 1991
and a director of NPFC since 1988. Dr. Hoffmann is a John A. Newman  Professor
of Physical  Science at Cornell  University  since 1974 and is a member of the
National  Academy of Sciences and the American  Academy of Arts and  Sciences.
In 1981, he shared the Nobel Prize in Chemistry with Dr. Kenichi Fukui.  Age 59.

       Sheldon L.  Glashow,  Ph.D.  has been a director of the Company  since
1991. He has been a director of GPC since 1987,  a director of GSE since 1995,
a director of CalCol,  Inc.  since 1994,  and was a director of Duratek from
1985 to 1995.  Dr.  Glashow is the Higgins  Professor  of Physics and the Mellon
Professor of the Sciences at Harvard  University.  He was a Distinguished
Professor and visiting Professor of Physics at Boston University.  In 1971, he
received the Nobel Prize in Physics. Age 65.

<PAGE>


Item 11.   Executive Compensation

       The following table presents the compensation  paid by the Company to its
Chief Executive Officer and the Company's four most highly compensated executive
officers for 1997.

<TABLE>

                                                    SUMMARY COMPENSATION TABLE

<CAPTION>


                                                                                       Long-Term
                                                                                     Compensation
                                                                                         Awards
                                                      Annual Compensation      -----------------------------
                                                      -------------------       Stock             All Other
                                    Year              Salary       Bonus       Options           Compensation
Name and Principal Position         ($)                 ($)         ($)          (#)                 ($)
- ---------------------------         ----              ------      ------       --------          ------------
<S>                                 <C>               <C>          <C>            <C>              <C>

Lawrence M. Gordon (1)              1997              135,000(1)     - 0 -        42,525             4,718(4)
Chief Executive Officer             1996              135,000(1)   150,000        25,000           168,000(2)
                                    1995               75,000(1)     - 0 -        27,000             -  0  -


Samuel H. Ronel, Ph.D.              1997              205,154        - 0 -        51,200             5,083(4)
Chairman of the Board               1996              145,905(3)    52,000        41,375             5,298(4)
                                    1995              146,563(3)     - 0 -        18,750             6,110(4)


Stanley G. Schutzbank, Ph.D.        1997              231,302        - 0 -        51,750             4,860(4)
President                           1996              197,341(5)    97,500        41,375             5,298(4)
                                    1995              188,818(5)     - 0 -        31,250             4,998(4)

Drew Stoudt                         1997              130,646        - 0 -        15,400             3,582(4)
Vice President, Regulatory          1996              119,452(6)    21,250        11,250             3,431(4)
Affairs and Quality                 1995              114,018(6)     - 0 -         6,250             2,974(4)


Mei-June Liao, Ph.D.                1997              122,380        - 0 -         7,325             3,744(4)
Vice President, Research            1996              115,568       21,250           125             3,324(4)
and Development                     1995              108,546        - 0 -         1,250             2,944(4)





- ------------
<FN>
(1)    Consists of $135,000 for 1997 and 1996 and $75,000 for 1995,  paid to Mr.
       Gordon  by  NPDC.  The  Company   reimbursed  NPDC  for  such  amount  in
       consideration of NPDC's  permitting Mr. Gordon to devote 60%, 60% and 33%
       of his working time to the Company for 1997, 1996 and 1995, respectively.
       Does  not  include  additional  salary  paid to Mr.  Gordon  by NPDC  for
       services rendered solely to NPDC for 1997, 1996 and 1995.

(2)    The  Company  forgave a  $150,000  loan to Mr.  Gordon  and also  forgave
       $18,000 of accrued  interest on such loan. Such loan had been due July 9,
       1997 and bore interest at a rate of 6% per annum.

(3)    Dr. Ronel has been  Chairman of the Board of the Company  since  February
       1997,  was Vice  Chairman  from  January 1996 to February  1997,  and was
       President  and Chief  Executive  Officer  until  January  1996.  Excludes
       $59,595 and $59,864 for 1996 and 1995, respectively,  paid by the Company
       to  Dr.  Ronel  for  which  the  Company  was   reimbursed   by  NPDC  in
       consideration  of the Company's  permitting Dr. Ronel to devote a portion
       of his working hours to NPDC.

(4)    Matching  contribution  by the  Company  to the 401(k)  Savings  Plan and
       payments by the Company for Group Term Life.

(5)    Dr.  Schutzbank  has been President of the Company since January 1996 and
       was Executive Vice President of the Company until January 1996.  Excludes
       $21,927 and $20,980 for 1996 and 1995, respectively,  paid by the Company
       to Dr.  Schutzbank  for  which  the  Company  was  reimbursed  by NPDC in
       consideration  of the  Company's  permitting  Dr.  Schutzbank to devote a
       portion of his working hours to NPDC.

(6)    Excludes $6,286 and $6,001 for 1996 and 1995,  respectively,  paid by the
       Company to Mr.  Stoudt for which the  Company was  reimbursed  by NPDC in
       consideration of the Company's  permitting Mr. Stoudt to devote a portion
       of his working hours to NPDC.

</FN>
</TABLE>


<PAGE>



                              Option Grants in 1997

       The following  table sets forth certain  information  relating to options
granted in 1997 to purchase shares of Common Stock of the Company.

<TABLE>

                                                                                             Potential Realizable  
                                                                                             Value at Assumed Annual
                                                                                              Rates of Stock Price
                                                % of Total                                     Appreciation for
                                  Options   Options Granted  Exercise or                         Option Term(2)
                                  Granted    to Employees    Base Price     Expiration      ------------------------
                                  (#) (1)       in 1997        ($/Sh)          Date             5%            10%
                                  -------   ---------------  -----------    ----------      ---------      ---------
<S>                               <C>              <C>        <C>            <C>              <C>          <C>

Lawrence M. Gordon                 6,250           1.1%       $ 8.00         02/20/2002       $13,813      $30,500
                                   6,250           1.1%       $ 9.18         06/12/2002       $15,875      $35,000
                                  16,900           2.9%       $ 5.00         05/02/2002       $23,322      $51,545
                                   6,250           1.1%       $ 8.00         09/22/2000       $ 7,875      $16,563
                                   6,875           1.2%       $ 8.69         12/31/2000       $ 9,419      $19,800

Samuel H. Ronel, Ph.D.            10,000           1.2%       $ 8.00         02/20/2002       $22,100      $48,800
                                  16,200           2.8%       $ 5.00         05/02/2002       $22,356      $49,410
                                  12,500           2.1%       $ 8.00         09/22/2000       $15,750      $33,125
                                  12,500           2.1%       $ 8.69         12/31/2000       $17,125      $36,000

Stanley G. Schutzbank, Ph.D.      10,000           1.2%       $ 8.00         02/20/2002       $22,100      $48,800
                                  16,750           2.8%       $ 5.00         05/02/2002       $23,115      $51,088
                                  12,500           2.1%       $ 8.00         09/22/2000       $15,750      $33,125
                                  12,500           2.1%       $ 8.69         12/31/2000       $17,125      $36,000

Drew Stoudt                        3,900            .7%       $ 5.00         05/02/2002       $ 5,382      $11,895
                                   6,250           1.1%       $ 8.00         09/22/2000       $ 7,875      $16,563
                                   5,000            .8%       $ 8.00         11/28/2000       $ 6,300      $13,250
                                     250            -         $ 8.69         12/31/2000       $   343      $   720

Mei-June Liao, Ph.D.               3,700            .6%       $ 5.00         05/02/2002       $ 5,106      $11,285
                                   2,500            .4%       $ 8.00         09/22/2000       $ 3,150      $ 6,625
                                   1,125            .2%       $ 8.00         11/28/2000       $ 1,418      $ 2,981



- --------------
<FN>
     The 5% and 10%  assumed  rates  of  stock  appreciation  used to  calculate
potential gains to optionees are mandated by the rules of the Commission.

(1) Options  were granted at 100% of fair market value on the date of the grant.
(2) Represents gain that would be realized assuming the options were held for
     the entire  three- and  five-year  terms and the stock price  increased  at
     compounded  rates of 5% and 10% from a base price of $8.00,  $9.18,  $5.00,
     $8.00 and $8.69.  The potential  realizable  values per option or per share
     under such 5% and 10% rates of stock  appreciation would be $2.21 and $4.88
     per share for the $8.00 share price (five-year  term);  $2.54 and $5.60 for
     the $9.18 share price; $1.38 and $3.05 for the $5.00 share price; $1.26 and
     $2.65 for the $8.00 share price (three-year  term); and $1.37 and $2.88 for
     the  $8.69  share  price.   These  amounts   represent   assumed  rates  of
     appreciations  only.  Actual gain,  if any, on stock  exercises  and Common
     Stock  holdings will be dependent on overall  market  conditions and on the
     future  performance  of the Company and its Common  Stock.  There can be no
     assurance that the amount reflected in this table will be achieved.
</FN>
</TABLE>

<PAGE>

     The following table sets forth information for the named executive officers
regarding  the  unexercised  options  held at the end of 1997.  No options  were
exercised by the named executive officers in 1997.

<TABLE>

                   AGGREGATED DECEMBER 31, 1997 OPTION VALUES

<CAPTION>


                                            Number of Unexercised            Value of Unexercised
                                                 Options at                  In-the-Money Options at
                                            December 31, 1997(#)             December 31, 1997($)(1)
                                            Exercisable/Unexercisable        Exercisable/Unexercisable
                                            -------------------------        -------------------------
<S>                                         <C>            <C>               <C>             <C>
Lawrence M. Gordon                          70,505         24,520            $101,089        $55,168
Samuel H. Ronel, Ph.D.                      90,865         20,460            $158,643        $55,321
Stanley G. Schutzbank, Ph.D.                98,475         25,900            $161,205        $58,381
Drew Stoudt                                 29,280          5,620            $ 54,523        $12,224
Mei-June Liao, Ph.D.                         8,240          5,460            $  6,479        $11,634















- -------------------
<FN>

(1)  Calculated  based on the closing  price of the Common  Stock  ($8.6875) as
     reported by NASDAQ on December 31, 1997.
</FN>

</TABLE>


<PAGE>


Item 12.  Security Ownership Of Directors And Named Executive Officers

Principal Stockholders

      The  following  table  sets  forth the  number  of shares of Common  Stock
beneficially  owned as of April 30,  1998,  by each  person  who is known by the
Company to own  beneficially  more than 5% of the Company's  outstanding  Common
Stock.

<TABLE>



Name and Address                                  Number of Shares            Percentage
of Beneficial Owner                               Beneficially Owned          of Class(1)
- -------------------                               ------------------          -----------
<S>                                                 <C>                          <C>

National Patent Development Corporation             1,854,287(2)                 12.2%
Martin M. Pollak                                    2,007,412(2)(3)              13.1%
Jerome I. Feldman                                   2,010,899(2)(4)              13.1%












- ---------------
<FN>
(1)   The percentage of class calculation assumes for each beneficial owner that
      all of the options or  warrants  are  exercised  in full only by the named
      beneficial  owner and that no other  options or warrants  are deemed to be
      exercised by any other stockholders.

(2)   Includes  (i)  1,514,444  shares of Common  Stock  owned by NPDC and (ii)
      339,843 shares of Common Stock owned by Five Star  Group,  Inc. ("FSGI").
      FSGI is a wholly-owned  subsidiary  of NPDC.  Based upon the common stock
      and Class B Stock of NPDC outstanding at March 31, 1998, Martin M. Pollak
      and Jerome I. Feldman, officers and directors of NPDC and directors of the
      Company,  controlled in the aggregate  approximately 6.8% of the voting
      power of all voting securities of NPDC.  This percentage for Mr. Pollak
      and Mr. Feldman would increase to approximately 42.8% if they exercised
      all of the presently  outstanding and currently  exercisable stock options
      to purchase shares of the common stock and Class B Stock of NPDC held by
      them.  Accordingly,  Messrs. Pollak and Feldman,  through their ownership
      of common stock and Class B Stock of NPDC, may be deemed to beneficially
      own the shares of Common Stock beneficially owned by NPDC and FSGI.
      However,  Messrs.  Pollak and Feldman  disclaim  beneficial  ownership of
      such 1,854,287  shares.  339,843 of the shares of Common Stock owned by
      FSGI have been pledged to a bank by NPDC as collateral to secure
      indebtedness  owed to such bank.  The address of NPDC and Messrs.  Pollak
      and Feldman is 9 West 57th Street,  Suite 4170, New York, New York, 10019.

(3)   Includes (i) 1,854,287 shares of Common Stock  beneficially owned by NPDC,
      (ii) 12,875 shares of Common Stock beneficially owned by Mr. Pollak, (iii)
      250 shares of Common  Stock held by Mr.  Pollak's  wife,  and (iv) 140,000
      shares of Common Stock  issuable  upon  exercise of currently  exercisable
      stock options held by Mr.Pollak.  Mr.Pollak disclaims beneficial ownership
      of the shares of Common Stock owned by NPDC and his wife.

(4)   Includes (i) 1,854,287 shares of Common Stock  beneficially owned by NPDC,
      (ii) 15,875  shares of Common  Stock  beneficially  owned by Mr.  Feldman,
      (iii) 737 shares of Common Stock held by certain members of Mr.  Feldman's
      family,  and (iv) 140,000 shares of Common Stock issuable upon exercise of
      currently  exercisable  stock  options held by Mr.  Feldman.  Mr.  Feldman
      disclaims beneficial ownership of the shares of Common Stock owned by NPDC
      and his family.
</FN>
</TABLE>


<PAGE>



      The following table sets forth, as of April 30, 1998, beneficial ownership
of shares of Common  Stock of the  Company by each  director,  each of the named
executive officers and all directors and executive officers as a group.

<TABLE>


                                                                        Of Total Number
                                                                           of Shares
                                                                         Beneficially
                                    Total Number        Percent of          Owned
                                      of Shares           Common         Shares which
                                    Beneficially          Stock        May be Acquuired
Name                                   Owned             Owned(1)       Within 60 Days
- ----                                 ----------         ----------     ----------------------
<S>                                  <C>                 <C>              <C>
Martin M. Pollak(2)(5)(7)             2,007,412           13.1%            140,000
Jerome I. Feldman(3)(5)(7)            2,010,899           13.1%            140,000
Samuel H. Ronel, Ph.D.(4)               100,480             *               94,105
Lawrence M. Gordon                       80,135             *               73,885
Stanley G. Schutzbank, Ph.D.            109,450             *              101,825
Drew Stoudt                              32,310             *               30,060
Mei-June Liao                            10,855             *                8,980
Scott N. Greenberg                       60,875             *               53,250
Leon Botstein, Ph.D.                      5,750             *                5,750
Roald Hoffmann, Ph.D.(6)                  5,250             *                5,250
Sheldon L. Glashow(6)                     5,250             *                5,250
Directors and Executive Officers
  as a Group (15 persons)             2,601,836           16.3%            685,510



 -------------
<FN>
 * The number of shares  owned is less than one  percent of the  outstanding
   shares of Common Stock.

 (1) The percentage of class  calculation  assumes for each beneficial owner
     that all of the options or warrants  are  exercised in full only by the
     named beneficial owner and that no other options or warrants are deemed
     to be exercised by any other stockholders.

 (2) See footnotes (2) and (3) to Principal Stockholders table.

 (3) See footnotes (2) and (4) to Principal Stockholders table.

 (4) Includes (i) 3,875 shares beneficially held by Dr. Ronel and (ii) 2,500
     shares of Common Stock held by Dr.  Ronel's wife.  Dr. Ronel  disclaims
     beneficial ownership of the shares of Common Stock owned by his wife.

 (5) Member of the Executive Committee.

 (6) Member of the Audit Committee.

 (7) Member of the Compensation Committee.
</FN>
</TABLE>


<PAGE>


 Item 13.  Certain Relationships and Related Transactions.

Agreements with NPDC

       Transfer Agreement. As of January 1, 1981, NPDC entered into an agreement
(the "Transfer  Agreement") with the Company pursuant to which NPDC (i) licensed
to the Company in  perpetuity  all of its right  title,  and  interest in and to
certain  intellectual  property and technology rights (the "Intangible  Assets")
relating to its programs in human  leukocyte  interferon and recombinant DNA and
hybridoma  technology,  and (ii)  transferred  to the Company  its rights  under
certain  consulting,  supply,  and research  agreements (the  "Agreements").  In
consideration  of the license  and  trnasfer  of the  Intangible  Assets and the
Agreements,  the Transfer Agreement provides that the Company will pay to NPDC a
royalty of $1,000,000.  Such amount is payable if and when the Company generates
net income before income taxes,  and is limited to 25% of such net income before
taxes per year until the amount is paid in full.

       Management  Agreement.  As of  January  1,  1981,  NPDC  entered  into  a
management  agreement (the "Management  Agreement") with the Company pursuant to
which certain legal, financial and administrative services have been provided by
employees of NPDC. The fee for such services is $120,000 per annum.

       Lease Agreement. The Company owns two free-standing buildings aggregating
approximately  44,000  square feet  located in New  Brunswick,  New Jersey.  The
Company and NPDC have entered  into an agreement  for the sharing of the office,
warehouse and laboratory  facility.  The Company occupies  approximately  25,000
square  feet,  shares  approximately  9,000  square  feet with NPDC,  and leases
approximately 10,000 square feet of space to NPDC at such location. During 1997,
NPDC paid the Company as rent NPDC's proportionate share of such occupancy costs
(based on both square feet occupied and number of personnel),  which amounted to
$234,996. The lease was terminated in March, 1998.

       While the  above-described  agreements  were  negotiated with a principal
stockholder of the Company which was then its parent,  the Company  nevertheless
believes  that  such  agreements  are  equivalent  economically  to  arms-length
transactions with a third party.

Other Transactions

       In January 1998, Messrs. Feldman, Pollak and Greenberg,  directors of the
Company,  received cash bonuses for services rendered to the Company at $50,000,
$50,000 and $25,000, respectively.

Employment Agreement

       As of October 1, 1997, Lawrence M. Gordon and the Company entered into an
employment  agreement  pursuant  to which Mr.  Gordon is  employed  as the Chief
Executive  Officer of the Company until December 31, 2001. On December 31, 1999,
and on each  December  31 of each  year  thereafter,  the  employment  period is
automatically  extended for one additional  year unless,  not later than June 30
immediately  preceding any such December 31, either party  delivers to the other
written notice that the employment period is not further extended.

       Commencing  January 1, 1997, Mr. Gordon's base annual salary is $250,000,
subject to annual  increases  of 6%. The Company  granted Mr.  Gordon  under the
Company's option plan options to purchase 150,000 shares of the Company's common
stock at an exercise price of $8.50.  Such options vest 20%  immediately and 20%
on each January 1 commencing January 1, 1998 and terminate on December 31, 2001.
The Company's Board of Directors may determine Mr. Gordon's bonus for each year,
and whether to grant Mr.  Gordon  additional  options,  based upon the Company's
revenues, profits or losses, financing activities,  progress in clinical trials,
and such other factors deemed relevant by the Board.

       The Company may terminate the  employment  agreement for Cause,  which is
defined as (i) the willful and continued  failure by Mr. Gordon to substantially
perform his duties or obligations or (ii) the willful  engaging by Mr. Gordon in
misconduct  which  is  materially   monetarily  injurious  to  the  Company.  If
employment agreement is terminated for Cause, the Company is required to pay Mr.
Gordon his full salary through the termination date.

       Mr. Gordon can terminate the employment  agreement for Good Reason, which
is defined  as (i) a change in  control of the  Company or (ii) a failure by the
Company to comply with any material provision of the employment  agreement which
has not been cured  within ten days after  notice.  A "change in control" of the
Company is defined as (i) a change in control of a nature that would be required
to be reported in response to Item 1(a) of Current  Report on Form 8-K  pursuant
to Section 13 or 15(d) of the  Securities  Exchange  Act of 1934 (the  "Exchange
Act"),  (ii) any "person"  (as such term is used in Sections  13(d) and 14(d) of
the Exchange Act) is or becomes the "beneficial owner" (as defined in Rule 13d-3
under the Exchange Act),  directly or  indirectly,  of securities of the Company
representing  20% or more of the  combined  voting power of the  Company's  then
outstanding  securities,  or  (iii)  at any time  individuals  who  were  either
nominated for election or elected by the Board of Directors of the Company cease
for any reason to constitute at least a majority of the Board.

       If the Company  wrongfully  terminates  the  employment  agreement or Mr.
Gordon terminates the employment agreement for Good Reason, then (i) the Company
is required to pay Mr. Gordon his full salary through the termination date; (ii)
the Company is required to pay as severance pay to Mr. Gordon an amount equal to
(a) Mr. Gordon's average annual cash  compensation  received from the Company or
GP  Strategies  Corporation  during the three full  calendar  years  immediately
preceding the termination date,  multiplied by (b) the greater of (I) the number
of years  (including  partial  years)  that  would  have been  remaining  in the
employment  period if the  employment  agreement had not so terminated  and (II)
three,  such  payment  to be made (c) if  termination  is  based on a change  of
control of the Company,  in a lump sum on or before the fifth day  following the
termination  date  or (d) if  termination  results  from  any  other  cause,  in
substantially  equal semimonthly  installments  payable over the number of years
(including  partial  years)  that would have been  remaining  in the  employment
period if the employment  agreement had not so terminated;  (iii) all options to
purchase the  Company's  common stock  granted to Mr. Gordon under the Company's
option plan or otherwise  immediately  become fully vested and terminate on such
date as they would have terminated if Mr. Gordon's employment by the Company had
not terminated and, if Mr. Gordon's  termination is based on a change of control
of the Company and Mr.  Gordon elects to surrender any or all of such options to
the Company,  the Company is required to pay Mr.  Gordon a lump sum cash payment
equal to the excess of (a) the fair market value on the termination  date of the
securities  issuable  upon  exercise  of the  options  surrendered  over (b) the
aggregate exercise price of the options surrendered;  and (iv) if termination of
the employment  agreement arises out of a breach by the Company,  the Company is
required  to pay all other  damages  to which Mr.  Gordon may be  entitled  as a
result of such breach. If the employment  agreement is terminated for any reason
other than Cause,  the Company is required to maintain in full force and effect,
for a number of years equal to the greater of (i) the number of years (including
partial years) that would have been  remaining in the  employment  period if the
employment  agreement had not so terminated and (ii) three, all employee benefit
plans and programs in which Mr. Gordon was entitled to  participate  immediately
prior to the termination date.

<PAGE>
                                   SIGNATURES

      Pursuant  to the  requirements  of Section 13 or 15(d) of the  Securities
Exchange  Act of 1934,  the  registrant  has duly  caused this report to be
signed on its behalf by the undersigned, thereunto duly authorized.


                                               INTERFERON SCIENCES, INC.



                                       By: /s/ Lawrence M. Gordon
                                               ------------------------
                                               Lawrence M. Gordon 
                                               Chief Executive Officer





Dated:  April 30, 1998

 









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