PRUDENTIAL SECTOR FUNDS INC
497, 2000-11-13
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                        Prudential Health Sciences Fund
                   a series of Prudential Sector Funds, Inc.
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                      Supplement Dated November 13, 2000
                       Prospectus Dated March 30, 2000

The following information supplements the information contained in the
Prospectus of the Fund on page 21.

How the Funds are Managed--Portfolio Managers

   David Chan and Michael A. Del Balso are the portfolio managers of the
Strategically Managed portfolio of the Fund. Mr. Chan has managed the
Strategically Managed portfolio of the Fund since its inception. Mr. Chan, a
Director and Senior Vice President of Jennison Associates LLC (Jennsion), joined
Jennison in 1992. Previously, Mr. Chan was employed at the Boston Consulting
Group, where he was a team leader and consultant on projects in many industries,
including pharmaceuticals and drug retailing and distribution. He received a
B.A. from Harvard University and an M.B.A. from Columbia University. Mr. Del
Balso, who became a co-portfolio manager on October 25, 2000, is a Director and
Executive Vice President of Jennison, where he has been part of the investment
team since 1972. Mr. Del Balso is also Jennison's Director of Equity Research.
Mr. Del Balso received his B.A. from Yale University and his M.B.A. from
Columbia University. He is a member of the New York Society of Security
Analysts. John Van Belle, Ph.D., has been the portfolio manager of the Enhanced
Index portfolio of the Fund since its inception. Mr. Van Belle is a Managing
Director in Prudential Investments' Quantitative Management (QM) group and
joined QM in 1983. He has managed mutual fund portfolios since 1988 and
investment portfolios for more than 15 years, and is responsible for managing
several equity, balanced and global balanced portfolios on behalf of
institutional and retail clients. Mr. Van Belle holds a B.S. from St. Joseph's
College and a Ph.D. from the University of Virginia.
MF188C


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