UNIGENE LABORATORIES INC
DEF 14A, 1997-05-19
MEDICINAL CHEMICALS & BOTANICAL PRODUCTS
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                            SCHEDULE 14A INFORMATION
                    Proxy Statement Pursuant to Section 14(a)
                     of the Securities Exchange Act of 1934

[ X ] Filed by the registrant

[   ] Filed by a party other than the registrant      


Check the appropriate box:

[   ] Preliminary Proxy Statement

[   ] Confidential, for Use of the Commission Only
      (as permitted by Rule 14a-6(e)(2))

[ X ] Definitive Proxy Statement

[   ] Definitive Additional Materials

[   ] Soliciting Material Pursuant to ss. 240.14a-11(c) or ss. 240.14a-12


                           Unigene Laboratories, Inc.
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified in Its Charter)
<PAGE> 
                           Unigene Laboratories, Inc.
                              110 Little Falls Road
                           Fairfield, New Jersey 07004
                                 (201) 882-0860


                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                           To be held on June 30, 1997

NOTICE IS HEREBY  GIVEN  that the  Annual  Meeting  of  Stockholders  of Unigene
Laboratories,  Inc., a Delaware corporation (the "Company"), will be held at the
offices of the Company, 83 Fulton Street,  Boonton, New Jersey 07005 on June 30,
1997, at 11:00 A.M., Eastern Daylight Time, for the following purposes:

     1. To elect directors of the Company;

     2. To approve an  amendment  to the  Certificate  of  Incorporation  of the
Company to increase the number of authorized  shares of Common Stock,  par value
$.01 per share, from 48,000,000 shares to 60,000,000 shares.

     3. To approve an amendment to the Company's 1994 Employee Stock Option Plan
to increase the total number of shares that may be sold by 750,000 shares.

     4. To ratify the  appointment  of KPMG Peat  Marwick LLP as auditors of the
Company; and

     5. To transact such other  business as may properly come before the meeting
and any and all adjournments thereof.

     The Board of Directors  has fixed the close of business on May 1, 1997,  as
the record date for the determination of stockholders who are entitled to notice
of and to vote at the meeting.

     A copy of the Company's Annual Report for the year ended December 31, 1996,
is sent to you herewith.

     To assure your representation at the meeting,  please sign, date and return
your proxy in the enclosed envelope,  which requires no postage if mailed in the
United States.

                                              By Order of the Board of Directors

                                              RONALD S. LEVY
                                              Secretary
May 12, 1997
<PAGE>
                           Unigene Laboratories, Inc.
                              110 Little Falls Road
                        Fairfield, New Jersey 07004-2193
                                 (201) 882-0860

                                 PROXY STATEMENT
                         ANNUAL MEETING OF STOCKHOLDERS

     This Proxy  Statement is furnished in connection  with the  solicitation of
proxies by the Board of  Directors  of Unigene  Laboratories,  Inc.,  a Delaware
corporation  (the  "Company"),  for the Annual  Meeting of  Stockholders  of the
Company to be held at the offices of the Company, 83 Fulton Street, Boonton, New
Jersey 07005, on June 30, 1997, at 11:00 A.M., Eastern Daylight Time.

     You are requested to complete, date and sign the accompanying form of proxy
and return it to the Company in the enclosed envelope.  The proxy may be revoked
at any time before it is  exercised by written  notice to the Company  bearing a
later date than the date on the proxy,  provided  such notice is received by the
Company prior to the start of the meeting. Any stockholder attending the meeting
may vote in person  whether or not he has  previously  submitted a proxy.  Where
instructions  are  indicated,  a duly executed proxy will be voted in accordance
with such  instructions.  Where no instructions  are indicated,  a duly executed
proxy will be voted for each of the director  nominees named herein and in favor
of each of the proposals set forth in the attached Notice.

     The Board of Directors  has fixed the close of business on May 1, 1997,  as
the record date (the "Record Date") for the  determination  of stockholders  who
are entitled to notice of and to vote at the meeting. As of the Record Date, the
outstanding  shares of the Company  entitled to vote were  36,998,412  shares of
common stock,  par value $.01 per share ("Common  Stock"),  the holders of which
are entitled to one vote per share.

     A majority of the outstanding shares of Common Stock,  present in person or
represented  by proxy,  will  constitute a quorum for the conduct of business at
the Annual Meeting.  Directors will be elected by a plurality of the votes cast.
The affirmative vote of a majority of the outstanding shares is required for the
approval of the  increase in the  authorized  shares of Common Stock and for the
approval of the  increase  in the total  number of shares that may be sold under
the 1994 Employee Stock Option Plan. The  affirmative  vote of a majority of the
votes  present  and  entitled to vote is required  for the  ratification  of the
appointment  of KPMG Peat  Marwick LLP as auditors of the  Company.  For matters
that require for adoption  the  affirmative  vote of a majority of the shares of
Common Stock  outstanding,  broker  non-votes and abstentions  will constitute a
vote against the matter.  For matters that require for adoption the  affirmative
vote of a majority of the shares of Common  Stock  present and entitled to vote,
abstentions  are  considered  as  shares  present  and  entitled  to  vote  and,
therefore, have the effect of a no vote, whereas broker non-votes are considered
shares not present and  entitled to vote and,  therefore,  have no impact on the
outcome of the vote.

     This  Proxy  Statement  and the  accompanying  Notice of Annual  Meeting of
Stockholders  and form of proxy are being mailed to the stockholders on or about
May 12, 1997. A copy of the Company's  Annual Report for the year ended December
31, 1996, is also enclosed.
<PAGE>
PRINCIPAL STOCKHOLDERS

     The following  table sets forth  information as of May 1, 1997,  concerning
the persons who are known by the Company to own beneficially more than 5 percent
of the outstanding shares of Common Stock, other than persons who are identified
under the heading "Security Ownership of Management".
<TABLE>
<CAPTION>

    Name and Address of           Amount of Beneficial            Percentage of
     Beneficial Owner                  Ownership              Outstanding Shares
     ----------------                  ---------              ------------------
<S>                                   <C>                            <C>
  Loews Corporation (1)               3,000,000                      7.9.%
  CNA Plaza
  Chicago, IL 60685

- ------------------ 
(1) Based on information furnished by Loews Corporation in a Schedule 13G, dated
  March 4, 1997,  filed with the Securities and Exchange  Commission in which it
  reports that the securities, which consist of 2,000,000 shares of Common Stock
  and  warrants  to  purchase  1,000,000  shares of Common  Stock,  are owned by
  Continental Casualty Company, which is owned by CNA Financial Corp., a company
  in which Loews Corporation has an 84% equity interest.
</TABLE>
SECURITY OWNERSHIP OF MANAGEMENT

     The following  table sets forth  information as of May 1, 1997,  concerning
the beneficial  ownership of Common Stock by each director of the Company,  each
executive officer of the Company listed in the Summary  Compensation  Table, and
all directors and executive officers of the Company as a group.
<TABLE>
<CAPTION>
                                                                       Common Stock of the Company
                                                                       ---------------------------
                Name of                                      Amount and Nature of                     Percent of
            Beneficial Owner                                 Beneficial Ownership(1)                     Class
            ----------------                                 -----------------------                     -----
<S>                                                               <C>                                    <C>
            Warren P. Levy                                        1,911,700 (2)                           5.2%
            Ronald S. Levy                                        1,926,700 (2)                           5.2%
            Jay Levy                                                439,950                               1.2%
            Robert F. Hendrickson                                    15,000                                --
            Robert G. Ruark                                          30,000 (3)                           0.1%
            George M. Weimer                                         30,000 (4)                           0.1%
            Directors and Executive Officers
            as a Group (6 persons)                                4,153,350 (2)(5)                       11.2%
- ----------------------
(1)  Unless otherwise noted, each listed person and each member of the group has
     reported that he has sole voting and sole dispositive power with respect to
     securities shown as beneficially owned by him.

(2)  Includes  200,000  shares of Common  Stock  held in a family  trust over on
     which Warren P. Levy and Ronald S. Levy in their capacity as trustees share
     voting and dispositive power.

(3)  Consists  solely of shares of Common  Stock that Mr. Ruark has the right to
     acquire pursuant to stock options that are exercisable immediately.
<PAGE>
(4)  Consists  solely of shares of Common Stock that Mr. Weimer has the right to
     acquire pursuant to stock options that are exercisable immediately.

(5)  Includes an  aggregate  of 60,000  shares of Common Stock that such persons
     have the right to acquire  pursuant to stock  options that are  exercisable
     immediately.
</TABLE>
                                   PROPOSAL 1
                              ELECTION OF DIRECTORS

     Six  directors  of the  Company  are to be  elected  at  the  meeting.  The
directors  will serve  until the Annual  Meeting of  Stockholders  to be held in
1998,  and  until  their  respective  successors  shall  have been  elected  and
qualified.

     Each of the persons named below is currently a director of the Company and,
except  for  Robert  F.  Hendrickson,  each was  elected  as a  director  at the
Company's Annual Meeting of Stockholders in 1996. Mr.  Hendrickson was elected a
director by the Board of  Directors in January  1997.  The Board of Directors of
the  Company  has  no  reason  to  believe  that  any of the  nominees  will  be
unavailable  for  election  as a  director.  However,  should any of them become
unwilling or unable to accept nomination for election,  the individuals named in
the enclosed proxy will vote for the election of a substitute  nominee  selected
by the Board of  Directors  or, if no such  person  is  nominated,  the Board of
Directors will reduce the number of directors to be elected.

     The following table sets forth certain  information with respect to the six
nominees.
<TABLE>
<CAPTION>
                                                                 Served
                                                               Continuously
              Name                              Age           as Director Since
              ----                              ---           -----------------
<S>                                             <C>                 <C>
              Warren P. Levy (1)                45                  1980
              Ronald S. Levy (1)                48                  1980
              Jay Levy (1)                      73                  1980
              Robert F. Hendrickson             64                  1997
              Robert G. Ruark                   55                  1993
              George M. Weimer                  78                  1984


- --------------------
(1)  Dr.  Warren P. Levy and Dr. Ronald S. Levy are brothers and are the sons of
     Mr. Jay Levy.
</TABLE>

     Dr.  Warren P. Levy,  a founder of the  Company,  has served as  President,
Chief  Executive  Officer and  director of the Company  since its  formation  in
November 1980. Dr. Levy holds a Ph.D. in biochemistry and molecular biology from
Northwestern   University  and  a  bachelor's   degree  in  chemistry  from  the
Massachusetts Institute of Technology.

     Dr. Ronald S. Levy, a founder of the Company,  has served as Vice President
and  director  of the  Company  since  its  formation  in  November  1980 and as
Secretary since May 1986. Dr. Levy holds a Ph.D. in bioinorganic  chemistry from
Pennsylvania  State University and a bachelor's degree in chemistry from Rutgers
University.
<PAGE>
     Mr. Jay Levy, a founder of the Company, has served as Chairman of the Board
of Directors and Treasurer of the Company since its formation in November  1980.
Mr. Levy is a part-time employee of the Company and devotes approximately 15% of
his time to the  Company.  From 1985  through  February  1991,  he served as the
principal  financial  advisor to the Estate of Nathan Cummings and its principal
beneficiary,   The  Nathan  Cummings   Foundation,   Inc.,  a  large  charitable
foundation. For the seventeen years prior thereto, he performed similar services
for the late Nathan Cummings, a noted industrialist and philanthropist.

     Mr. Robert F.  Hendrickson  has been a director  since  January  1997.  Mr.
Hendrickson was Senior Vice President, Manufacturing and Technology, for Merck &
Co., Inc., an  international  pharmaceutical  company,  from 1985 to 1990. Since
1990,  Mr.  Hendrickson  has  been a  management  consultant  with a  number  of
biotechnology and  pharmaceutical  companies among his clients.  He is currently
Chairman of the Board of Envirogen, Inc. an environmental biotechnology company,
and a director of Cytogen,  Inc. and The Liposome Co.,  Inc.,  both of which are
biotechnology companies.

     Mr.  Robert G. Ruark has been an  independent  consultant  since June 1993.
Prior  thereto,  he had been employed by Merck and Co.,  Inc., an  international
pharmaceutical  company,  for 25  years  in  various  legal  and  administrative
capacities.  Mr. Ruark, an attorney,  has extensive  experience in international
licensing and business development.  When he retired in 1993, Mr. Ruark was Vice
President of the Merck Human Health Division.

     Mr. George M. Weimer has been an independent  general  partner and director
of Westford  Technology  Ventures L.P., a venture  capital  investment  company,
since May 1988.  For more than 40 years  prior  thereto,  Mr.  Weimer  worked in
various administrative capacities for divisions and subsidiaries of Merck & Co.,
Inc.  and  E.R.   Squibb  &  Sons,   both  of  which  are  major   international
pharmaceutical  companies.  When he retired in 1984,  Mr. Weimer was Senior Vice
President-Administration for Merck Sharp & Dohme International  Pharmaceuticals,
Inc.,  a  position  he had held  since  1981.  Since  1984,  he has  served as a
pharmaceutical  consultant  for the Company  and,  from time to time,  for other
corporations.

BOARD OF DIRECTORS AND COMMITTEES

     The Board of Directors of the Company does not have standing  nominating or
compensation committees. The members of the Audit Committee are Jay Levy, Robert
G. Ruark and George M. Weimer. The Audit Committee consults with the independent
certified public accountants and reviews the reports submitted by such auditors.

     During 1996,  there were four  meetings of the Board of  Directors  and one
meeting of the Audit Committee.

     Directors who are neither  employees nor consultants on retainer  receive a
fee of $1,000  for each  Board  meeting  attended.  Mr.  Robert G. Ruark and Mr.
Robert F.  Hendrickson  are the only  directors  who  qualified  for such  fees.
Although not on retainer,  Mr.  Ruark is entitled to  consulting  fees of either
$500 or $1,000 per day, depending on the type of project. No such fees were paid
to Mr. Ruark in 1996. Mr. George M. Weimer  receives a $1,000 per month retainer
for  consulting  services.  Mr. Weimer is also  entitled to receive  commissions
ranging  from 1% to 3% on  revenues  procured  by him for the  Company.  No such
commissions  have been  earned to date.  The Company  believes  that the fee and
commission arrangements with Mr. Ruark and Mr. Weimer are no more favorable than
would be paid to unaffiliated third parties. Audit Committee members do not earn
additional compensation.
<PAGE>
     In 1994,  the  Company's  stockholders  approved  the  adoption of the 1994
Outside  Directors  Stock Option Plan (the "Plan").  Under the Plan, each person
who was an outside director at the time of the adoption of the Plan was granted,
and each person who subsequently is elected as an outside director is granted, a
ten-year  option to purchase  30,000 shares of Common Stock at an exercise price
equal to the  market  price of the Common  Stock on the date of the  grant.  The
options vest in equal annual increments over the three-year period following the
grant.  If the  recipient's  service as a director  terminates,  the option will
expire three (3) months after the date of such termination. Messrs. Hendrickson,
Ruark and Weimer each have received under the Plan grants of options to purchase
30,000 shares.

REPORT OF THE BOARD OF DIRECTORS ON 1996 EXECUTIVE COMPENSATION

     The entire Board of Directors  was  responsible  for  determining  the 1996
compensation  of the  three  executive  officers  of the  Company.  This  Report
describes  the  policies  and  other   considerations   used  by  the  Board  in
establishing such compensation.

     The  members  of the Board are  familiar  with  various  forms and types of
remuneration  from reports of other public  corporations  and their own business
experience.

     The Board has determined that,  because the Company was still in a research
and preproduction  phase in 1996,  compensation for 1996 for executive  officers
could not be related  primarily to the  performance of the Company's stock or to
the annual profit  performance of the Company.  A primary  consideration for the
compensation of an executive  officer of the Company is his leadership effort in
the  development  of  proprietary  products and  processes,  and in planning for
future growth and  profitability.  Other significant  factors  considered by the
Board of Directors in determining executive officers' compensation were salaries
paid by other public companies in the health-care related biotechnology field to
comparable  officers,  the duties and responsibilities of the executive officers
in the past and as  projected,  their past  performance  and  commitment  to the
Company,  and incentives for future performance,  although no specific weighting
was allocated to any of these  considerations.  The executive officers were also
consulted with respect to their  compensation  and their plans for  compensation
for other  personnel in order to  coordinate  all  compensation  policies of the
Company.

     The Board of  Directors  determined  that no  bonuses  or salary  increases
should be paid to  executive  officers  in 1996,  primarily  on the basis of the
Company's  losses and the  projected  expenses  and cash flow  required  for the
further  development  and clinical  trials for the Company's  calcitonin pill as
well as the regulatory expenses and clinical trials for the Company's injectable
form of calcitonin.

     The Board also  determined  that no stock  options be awarded to  executive
officers for 1996, at the request of such executive officers.

     The compensation for the Chief Executive  Officer for 1996 was based on the
same  policies  and  considerations  set  forth  above  for  executive  officers
generally.

                                                  Warren P. Levy
                                                  Ronald S. Levy
                                                  Jay Levy
                                                  Robert G. Ruark
                                                  George M. Weimer
<PAGE>
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

     Executive compensation for 1996 was determined by the Board of Directors of
the Company  consisting  of Messrs.  Warren P. Levy,  Ronald S. Levy,  Jay Levy,
Robert G. Ruark, and George M. Weimer.

     Three of the members of the Board of Directors,  Warren P. Levy,  Ronald S.
Levy and Jay Levy, are executive officers of the Company. Jay Levy is the father
of Warren and Ronald Levy.

     During 1995,  Warren P. Levy,  Ronald S. Levy,  Jay Levy and another family
member  loaned a total of  $1,905,000  to the  Company of which  $1,850,000  was
secured by secondary  liens on the Fairfield plant and equipment and the Boonton
manufacturing  equipment.  The notes bear  interest at the Merrill  Lynch Margin
Loan Rate plus .25% (8.875% at April 15, 1997). Under the terms of the Company's
9.5% Senior Secured  Convertible  Debentures,  for so long as the Debentures are
outstanding,  repayment  of the  loans is  contingent  upon the  achievement  of
certain  corporate  benchmarks  and  is  subject  to  a  maximum  limitation  of
$1,250,000.  A total of $440,000 in  principal  payments  was made during  1996,
leaving an  outstanding  balance of $1,465,000 at December 31, 1996. No interest
has been paid to date.

EXECUTIVE COMPENSATION

     The  following  table  sets  forth  for  the  years  1996,  1995  and  1994
compensation  paid to the Chief  Executive  Officer of the  Company  and to each
other  executive  officer  whose  compensation  in 1996  exceeded  $100,000  for
services  rendered by such  executive  officers in all  capacities in which they
served:
<TABLE>
<CAPTION>
                                               SUMMARY COMPENSATION TABLE

                                                                                                           All Other
                                      Annual Compensation               Long Term Compensation          Compensation(1)
                                      -------------------               -----------------------         --------------- 
                                                                               Awards           Payouts
                                                                               ------           -------
                                                          Other        Restricted
Name and                                                  Annual          Stock     Options/      LTIP
Principal Position        Year       Salary    Bonus    Compensation      Award       SARs       Payouts
- ------------------        ----       ------    -----    ------------      -----       ----       -------
<S>                       <C>       <C>        <C>         <C>            <C>        <C>          <C>      <C>
Warren P. Levy,           1996      $145,454   $ -0-       $ -0-          $ -0-      $ -0-        $ -0-    $ 13,806
  President, Chief        1995       145,394     -0-         -0-            -0-        -0-          -0-      13,811
  Executive Officer       1994       145,344     -0-         -0-            -0-        -0-          -0-      12,942
  and Director
Dr. Ronald S. Levy,       1996       140,889     -0-         -0-            -0-        -0-          -0-      16,746
  Vice President and      1995       140,829     -0-         -0-            -0-        -0-          -0-      16,616
  Director                1994       140,716     -0-         -0-            -0-        -0-          -0-      13,914


- ---------------- 
(1)  Represents  premium  paid by the  Company on  executive  split-dollar  life
     insurance.
</TABLE>
<PAGE>
                   STOCKHOLDER RETURN PERFORMANCE PRESENTATION

     Set forth below is a line graph comparing the yearly  percentage  change in
the cumulative  total  stockholder  return on the Company's Common Stock against
the cumulative total return of the NASDAQ Market Index and of a peer group index
determined by Standard Industrial Classification (SIC) code.


                     COMPARE 5-YEAR CUMULATIVE TOTAL RETURN
                        AMONG UNIGENE LABORATORIES, INC.
                     NASDAQ MARKET INDEX AND SIC CODE INDEX


                 [GRAPHIC-GRAPH PLOTTED TO POINTS LISTED BELOW]
<TABLE>
<CAPTION>

                                             FISCAL YEAR ENDING
                              --------------------------------------------------
COMPANY                       1991     1992     1993     1994     1995     1996
- -------                       ----     ----     ----     ----     ----     ----
<S>                           <C>     <C>       <C>     <C>      <C>      <C>
UNIGENE LABS INC              100     101.52     60.61   57.58    31.82    49.24
INDUSTRY INDEX                100      82.68     68.63   46.07    89.42    79.54
BROAD MARKET                  100     100.98    121.13  127.17   164.96   204.98
</TABLE>

                         The industry index chosen was:
           SIC Code 8731 - Commercial Physical & Biological Research
          The current composition of the industry index is as follows:

 
Abiomed Inc.
AC Nielsen Corp.
Affymetrix Inc.
Amerigon Inc. CL A
Aura Systems Inc.
Avigen Inc.
Cadus Pharmaceutical CP
Catalytica Inc.
Celgene Corp.
Cocensys Inc.
Collaborative Clin Res
Conductus Inc.
Core Laboratories N.V.
Covance Inc.
Cree Research Inc.
CV Therapeutics Inc.
Cyclo 3 PSS Corp.
Ecogen Inc.
Ecoscience Corp.
Electronic Designs Inc.
Electrosource Inc.
Energy Biosystems Corp.
Energy Conversn Devices
Excel Technology Inc.
Fiberchem Inc.
Genset ADR
<PAGE>
Illinois Superconductor
Incyte Pharmaceuticals
Innerdyne Inc.
Integrated Process Equip.
Irvine Sensors Corp.
KFX Inc.
Kopin Corp.
Krug Internat Corp
Life Medical Science Inc.
Lifecell Corporation
Liposome Co. Inc.
Myriad Genetics Inc.
Neopharm Inc.
Neose Technologies Inc.
Neotherapeutics Inc.
Neurocrine Biosciences
Organogenesis Inc.
Pacific Biometrics Inc.
Parexel Internat CP
Pharmaceutical Prod Dev
Pharmacopeia Inc.
Polymer Research of Amer
Primark Corp.
Protein Polymer Tech
Quintiles Transational
Research Frontiers Inc.
Satcon Technology Corp.
SI Diamond Technol
Spire Corp.
Summit Technology Inc.
Superconductor Tech.
Synaptic Pharmaceutical
Valence Technology Inc.
Xenova GR PLC ADS
XXSYS Technologies Inc.
<PAGE>
                                   PROPOSAL 2
        AMENDMENT OF CERTIFICATE OF INCORPORATION TO INCREASE AUTHORIZED
                COMMON STOCK FROM 48,000,000 TO 60,000,000 SHARES

     The Board of Directors  unanimously has adopted  resolutions  approving and
recommending that the stockholders adopt an amendment to Paragraph FOURTH of the
Company's  Certificate  of  Incorporation  to increase the number of  authorized
shares of Common  Stock,  par value $.01 per share,  from  48,000,000  shares to
60,000,000 shares.  Shares of the Common Stock do not have preemptive or similar
rights.

     As of April 15,  1997,  the  Company  had a total of  37,005,702  shares of
Common Stock issued and  outstanding  and a total of 7,987,918  shares of Common
Stock reserved for issuance as follows:
<TABLE>
<CAPTION>
                                                          No. of Shares Reserved
                                                          ----------------------
<S>                                                             <C>
         1984 Employee Stock Option Plan                          198,650
         1994 Employee Stock Option Plan                        1,500,000
         1994 Outside Director Stock Option Plan                  180,000
         Convertible Debentures                                   774,362
         Warrants                                               5,319,906
         Other Options                                             15,000
                                                                ---------
         Total Shares Reserved                                  7,987,918
</TABLE>

     The Board of  Directors  of the Company  believes  that the increase in the
number of  authorized  shares of Common  Stock is in the best  interests  of the
Company  and  its  stockholders.  The  Board  of  Directors  believes  that  the
authorized  Common Stock should be  increased to provide  sufficient  shares for
such  corporate  purposes as may be  determined  by the Board of Directors to be
necessary or  desirable.  The Board of Directors  considers  the increase of the
authorized  number  of  shares  of  Common  Stock  essential  to  ensure  prompt
availability of shares for issuance should  transactions  requiring the issuance
of additional shares, warrants or options be consummated.  Also, the outstanding
warrants and options have,  and any warrants or options issued in the future may
contain, anti-dilution provisions requiring adjustments which would increase the
number  of  shares   subject  to  such   warrants  and  options   under  certain
circumstances.

     Under  the  Delaware  General  Corporation  Law,  the  Board  of  Directors
generally  may issue  authorized  but unissued  shares of Common  Stock  without
further stockholder  approval.  The Board of Directors does not currently intend
to seek  stockholder  approval  prior to any future  issuance of the  additional
authorized shares of Common Stock,  unless  stockholder  action is required in a
specific  case by  applicable  law, the rules of any exchange or market on which
the Company's securities may then be listed, or the Certificate of Incorporation
or By-Laws of the Company then in effect.  Frequently,  opportunities arise that
require prompt action,  and the Company believes that the delay necessitated for
stockholder  approval of a specific  issuance  could be to the  detriment of the
Company and its stockholders.
<PAGE>
     The additional  shares of Common Stock authorized for issuance  pursuant to
this  proposal  will have all of the rights and  privileges  that the  currently
outstanding  shares of Common Stock possess under the Company's  Certificate  of
Incorporation.  The increase in authorized  shares would not affect the terms or
rights of holders of existing shares of Common Stock. All outstanding  shares of
Common  Stock  would  continue  to have one vote per share on all  matters to be
voted on by the stockholders, including the election of directors.

     The issuance of any  additional  shares of Common Stock by the Company may,
depending  on the  circumstances  under  which those  shares are issued,  reduce
stockholders'  equity per share and would  reduce the  percentage  ownership  of
Common Stock of existing stockholders.

     The  authorized  but unissued  shares of Common Stock could be used to make
more  difficult a change in control of the  Company.  For  example,  such shares
could be sold to  purchasers  who  might  side with the  Board of  Directors  in
opposing  a  takeover  bid  that  the  Board  determines  not to be in the  best
interests of the Company and its stockholders. Such a sale could have the effect
of discouraging an attempt by another person or entity,  through the acquisition
of a  substantial  number of shares of the Company's  Common  Stock,  to acquire
control of the Company, since the issuance of new shares could be used to dilute
the stock ownership of the acquirer.  Neither the  Certificate of  Incorporation
nor  By-Laws of the Company  now  contains  any  provisions  that are  generally
considered  to have an  anti-takeover  effect.  The  Company is not aware of any
pending or threatened efforts to obtain control of the Company.

     To accomplish  the increase of the authorized  shares of Common Stock,  the
following   resolution   authorizing   the  amendment  of  the   Certificate  of
Incorporation will be submitted to a vote of the stockholders at the meeting:

     "RESOLVED,  that the Certificate of  Incorporation  of this  corporation be
     amended by changing  the Fourth  Article  thereof so that,  as amended said
     Article shall be and read as follows:

     FOURTH:  The total  number of shares of stock which the  Corporation  shall
     have authority to issue is sixty million  (60,000,000),  having a par value
     of $.01 per share. All such shares are of one class and are common stock."

     Approval of the resolution authorizing the amendment to increase the number
of  authorized  shares of Common  Stock  requires  the  affirmative  vote of the
holders of a majority of the outstanding shares of Common Stock.

     THE BOARD OF DIRECTORS  RECOMMENDS A VOTE FOR THE APPROVAL OF THE AMENDMENT
TO THE  COMPANY'S  CERTIFICATE  OF  INCORPORATION  TO  INCREASE  THE  NUMBER  OF
AUTHORIZED SHARES OF COMMON STOCK FROM 48,000,000 TO 60,000,000 SHARES.
<PAGE>
                                   PROPOSAL 3
           AMENDMENT TO THE COMPANY'S 1994 EMPLOYEE STOCK OPTION PLAN

     On June 17,  1994,  the  stockholders  approved  the  adoption  of the 1994
Employee  Stock  Option  Plan  ("1994  Plan").  The 1994 Plan  provides  for the
issuance of a maximum of 1,500,000  shares of Common  Stock.  Through  April 15,
1997,  options for an aggregate  of  1,442,250  shares of Common Stock have been
granted.  After  taking  into  account  the  cancellation  of options for 85,200
shares,  142,950 shares remain  available for option grants under the 1994 Plan.
Of the total  options  granted,  538,750  were  granted  pursuant to an employee
"swap" agreement to replace an equal number of shares  previously  granted under
the Company's 1984 Employee Stock Option Plan. The 1994 Plan  terminates on June
16, 2004. The text of the 1994 Plan, as currently in effect, is set forth in the
Appendix to this Proxy Statement and is hereby incorporated by reference.

     On April 8, 1997, the Board of Directors adopted,  subject to and effective
upon stockholder approval, an amendment to the 1994 Plan to increase the maximum
number of shares  authorized for issuance by 750,000 shares to 2,250,000 shares.
The  purpose of the  amendment  is to enable the  Company to continue to provide
employees of the Company with  opportunities  to purchase  stock in the Company,
thereby increasing their motivation for and interest in the Company's  long-term
success.

Federal Income Tax Information

     The following brief description of the tax consequences of awards under the
1994 Plan is based on Federal tax laws  currently in effect and does not purport
to be a complete description of such Federal tax consequences.

     There are no Federal  tax  consequences  either to the  optionee  or to the
Company upon the grant of an Incentive  Stock Option ("ISO") or a  Non-qualified
Stock  Option  ("NQSO").  On the  exercise  of an ISO,  the  optionee  will  not
recognize  any income  and the  Company  will not be  entitled  to a  deduction,
although  such exercise may give rise to  alternative  minimum tax liability for
the  optionee.  Generally,  if the  optionee  disposes of shares  acquired  upon
exercise of an ISO within two years of the date of grant or one year of the date
of exercise,  the optionee will recognize  ordinary income, and the Company will
be entitled to a deduction,  equal to the excess of the Fair Market Value of the
shares on the date of exercise over the option price  (limited  generally to the
gain on the sale).  The balance of any gain, and any loss,  will be treated as a
capital  gain or loss to the  optionee.  If the shares are disposed of after the
foregoing holding  requirements are met, the Company will not be entitled to any
deduction,  and the entire  gain or loss for the  optionee  will be treated as a
capital gain or loss.

     On  exercise  of an NQSO,  the excess of the  date-of-exercise  Fair Market
Value of the shares  acquired over the option price will generally be taxable to
the optionee as ordinary  income and deductible by the Company.  The disposition
of shares  acquired upon exercise of a NQSO will  generally  result in a capital
gain or  loss  for the  optionee,  but  will  have no tax  consequences  for the
Company.

     Under the terms of the 1994 Plan,  approval of the  resolution  authorizing
the amendment to increase the total number of shares of Common Stock that may be
sold  under  the  Company's   1994  Employee  Stock  Option  Plan  requires  the
affirmative  vote of the  holders of a  majority  of the  outstanding  shares of
Common Stock.

     THE  BOARD  OF  DIRECTORS  RECOMMENDS  APPROVAL  OF  THE  AMENDMENT  TO THE
COMPANY'S 1994 EMPLOYEE STOCK OPTION PLAN.
<PAGE>

                                   PROPOSAL 4
             RATIFICATION OF THE APPOINTMENT OF INDEPENDENT AUDITORS

     The Board of Directors  has  appointed  KPMG Peat Marwick LLP,  independent
public  accountants,  to serve as the  Company's  independent  auditors  for the
fiscal year commencing  January 1, 1997.  Although not required by the Company's
Certificate of Incorporation or By-Laws, the Board of Directors is submitting to
a vote of the  stockholders  a proposal to ratify the  appointment  of KPMG Peat
Marwick LLP.  KPMG Peat Marwick LLP served as the  independent  auditors for the
Company for the year ended December 31, 1996. A representative  of the firm will
be present at the meeting to respond to appropriate  questions and will have the
opportunity to make a statement, if such representative desires to do so.

     Ratification  of the  appointment  of KPMG Peat  Marwick LLP  requires  the
affirmative  vote of a  majority  of the  shares of  Common  Stock  present  and
entitled to vote.

     THE BOARD OF DIRECTORS  RECOMMENDS A VOTE FOR THE RATIFICATION OF KPMG PEAT
MARWICK LLP.

OTHER MATTERS

     The Board of Directors  of the Company  does not know of any other  matters
that are likely to be brought before the meeting. However, in the event that any
other  matters  properly  come  before the  meeting,  the  persons  named in the
enclosed form of proxy will vote all proxies  received in accordance  with their
judgment on such matters.

PROPOSALS BY STOCKHOLDERS

     Proposals of stockholders intended to be presented at the Annual Meeting of
Stockholders  of the Company to be held in 1998, must be received by January 12,
1998,  if they are to be included in the Company's  Proxy  Statement and form of
proxy relating to such meeting.

SOLICITATION OF PROXIES

     The cost of preparing,  assembling  and mailing this Proxy  Statement,  the
Notice of Meeting and the  enclosed  form of proxy will be borne by the Company.
In addition to the  solicitation of proxies by use of the mails, the Company may
utilize the  services of some of its officers  and regular  employees  (who will
receive no  compensation  therefor  in addition to their  regular  salaries)  to
solicit  proxies  personally  and by  telephone  and  telefax.  The  Company has
retained Regan & Associates,  Inc. to aid in the  solicitation  of proxies,  for
which such firm will be paid a fee of $5,000 plus reimbursable expenses.

                                              By Order of the Board of Directors

                                              RONALD S. LEVY
                                              Secretary
Fairfield, New Jersey
May 12, 1997
<PAGE>
                                                                        Appendix

                           UNIGENE LABORATORIES, INC.
                         1994 EMPLOYEE STOCK OPTION PLAN

     1.  Purpose.  This  Employee  Stock Option Plan (the "Plan") is intended to
provide  incentives  to selected  employees of Unigene  Laboratories,  Inc. (the
"Company")  by  providing  them  with  opportunities  to  purchase  stock in the
Company,  thereby  increasing their motivation for and interest in the Company's
long term success. The term Company shall include controlled  subsidiaries where
the context requires.

     2.  Administration.  The Plan shall be administered  either by the Board of
Directors of the Company (the "Board") or by a Committee  (the  "Committee")  of
not less  than two  directors  of the  Company.  Each  member  of such  Board or
Committee  shall be a person who, at the time of his  appointment to, and at all
times during his service as a member thereof  satisfies the requirements of Rule
16b-3  promulgated  under  the  Securities  Exchange  Act of  1934,  as  amended
("Exchange  Act"),  or any successor  statute or  regulation  regarding the same
subject matter.

     The Board or the Committee  shall have  authority,  subject to the terms of
the Plan,  to determine  the  employees  eligible for grant of options under the
Plan,  the employees to whom options shall be granted,  whether the option is an
Incentive Stock Option or a Non-qualified  Stock Option, the number of shares to
be covered by each option,  the time or times at which options shall be granted,
the  option  price,  the term of the  option,  the date or dates  upon which the
option may be  exercised,  and the  installments,  if any, in which  options may
become  exercisable,  and the terms and  provisions of the  instruments by which
options   shall  be  evidenced;   to  interpret  the  Plan;   and  to  make  all
determinations  necessary or advisable for the  administration  of the Plan. The
Board or the Committee shall also have the authority to grant to any holder of a
stock  option  under  this Plan a new  stock  option  in  substitution  for such
holder's  existing option under this Plan which,  upon his acceptance of the new
option,  would be cancelled,  and may also grant an additional option or options
to any holder of an option under this Plan or any other plan.

     No member  of the Board or the  Committee  shall be liable  for any  action
taken or omitted or for any determination made in good faith with respect to the
Plan or any option granted under the Plan.

     3.  Eligibility.  Options may be granted only to persons who are  employees
(including officers and directors who are employees) of the Company, and, in the
discretion of and as conclusively determined by the Board or the Committee,  may
include employees on authorized leave of absence.

     4. Stock.  The stock as to which  options  may be granted is the  Company's
common  stock  ("Common  Stock").  When options are  exercised,  the Company may
either issue unissued shares of Common Stock or transfer issued shares of Common
Stock held in its  treasury.  The total amount of Common Stock which may be sold
under the Plan shall not exceed one million  five hundred  thousand  (1,500,000)
shares  (subject to  adjustment  as provided in Section 7 herein).  In the event
that any  outstanding  option  under  the  Plan,  for any  reason,  expires,  is
surrendered  or  terminated  or is  canceled  after a  substitution  pursuant to
Section 2 hereof  prior to the  exercise  thereof  with respect to any shares of
Common Stock covered  thereby,  such shares shall be available  for  re-offering
under the Plan.
<PAGE>
     5.  Granting of Options.  Options may be granted under the Plan at any time
prior to the tenth (10th)  anniversary  of the effective date of the Plan as set
forth in Section 11 hereof.  The date of grant of an option under the Plan shall
be the date on which the option is awarded by the Committee or the Board.

     6.  Terms  and  Conditions  of  Options.  Options  may  be in the  form  of
"incentive stock options" as that term is defined in Section 422 of the Internal
Revenue  Code of 1986,  as amended  ("Code"),  herein  called  "Incentive  Stock
Options",  or in the form of options  which are not  described in Section 422 or
Section 423 of the Code, herein called  "Non-qualified  Stock Options".  Options
granted  under this Plan shall be evidenced by  instruments  in such form as the
Committee  or the Board  may from time to time  approve.  Such  options  and the
instruments issued to evidence such options shall conform to the following terms
and conditions:

     (a) Number of Shares.  The option shall be granted for a specific number of
         shares of Common Stock.

     (b) Option  Price.  The  purchase  price at which an option  may be granted
         shall be not less than the Fair Market Value of the Common Stock at the
         time the option is granted or the par value thereof,  if any, whichever
         is greater.  Fair Market  Value of a share of Common  Stock on any date
         means the average of the closing sales price of a share of Common Stock
         as  reflected  in the  report of  trading  by the  principal  quotation
         service,  market or stock  exchange on which the Common Stock is traded
         or listed on such date (or, if no such shares were  publicly  traded on
         that date,  the next preceding date that such shares were so traded) as
         published  in The  Wall  Street  Journal  or in any  other  publication
         selected  by the Board or the  Committee;  provided,  however,  that if
         shares of Common  Stock  shall not have been  publicly  traded for more
         than ten (10)  days  immediately  preceding  such  date,  then the Fair
         Market  Value of a share of Common  Stock  shall be  determined  by the
         Board or the  Committee in such manner as it may deem  appropriate  and
         its decision shall be final and binding.

     (c) Payment. The option price shall be payable upon the exercise,  in whole
         or in part, of the option,  in cash, or to the extent authorized by the
         Board or the Committee  prior to the time the option is  exercised,  in
         shares of Common Stock or in a combination of cash and such shares. The
         value of a share of Common  Stock  delivered in payment of the purchase
         price  shall  be its Fair  Market  Value  on the  date  the  option  is
         exercised.  No shares  shall be issued or  transferred  to an  optionee
         until full payment therefor has been made.

     (d) Term of Options.  Each option  granted  shall  expire no later than ten
         (10) years after the date of its grant.

     (e) Exercise of Option. Each option shall become exercisable in one or more
         installments  at the  time or times as  specified  in the  grant of the
         option.  Once an  installment  becomes  exercisable,  it  shall  remain
         exercisable in whole or in part until  expiration or termination of the
         option,  except as  hereinafter  set forth in Section 7. No  fractional
         shares shall be issued or cash  adjustment for  fractional  shares made
         upon exercise of an option.
<PAGE>
     (f) Death and Other  Termination  of  Employment.  Any option which has not
         theretofore expired, shall terminate upon termination of the optionee's
         employment  with the  Company  whether  by death or  otherwise,  and no
         shares of Common Stock may  thereafter  be  purchased  pursuant to such
         option,  except that: 

         (i)  Upon termination of employment (other than by death or for Cause),
              an  optionee  may,  within  three  (3)  months  after  the date of
              termination of employment,  purchase all or any part of the shares
              of Common Stock which such optionee was entitled to purchase under
              such option on the date of termination of employment.

         (ii) Upon the death of any optionee  while employed with the Company or
              within the  three-month  period  referred  to in  Section  6(f)(i)
              above, the optionee's estate or the person to whom such optionee's
              rights  under the  option are  transferred  by Will or the laws of
              descent and distribution may, within one hundred eighty (180) days
              after the date of such optionee's death,  purchase all or any part
              of the shares of Common Stock which such  optionee was entitled to
              purchase  under such option on the date of death.  Nothing in this
              Section 6(f) shall  authorize  the exercise of an option after the
              expiration of the exercise period therein provided, nor later than
              ten (10) years after the date of grant.

         (iii)If employment  of an optionee by the Company  terminates by reason
              of discharge for Cause, the option shall terminate upon the giving
              of notice of  termination  to the  optionee or on the  termination
              date stated in the option,  whichever  is earlier.  The term Cause
              shall mean discharge from employment because of fraud,  disclosure
              of trade secrets,  activities in competition  with the business of
              the   Company,   misappropriation   of  assets  of  the   Company,
              intentional  acts  materially   harmful  to  the  Company  or  its
              business, or conviction of a crime involving moral turpitude.

     (g) Assignability.  No option granted under the Plan shall be assignable or
         transferable  by the optionee  except by Will or by the laws of descent
         and distribution,  and during the lifetime of the optionee, each option
         shall be exercisable only by the optionee or a duly appointed committee
         for an incompetent optionee.

     (h) Taxes and  Withholding.  The  Company's  obligation  to deliver  shares
         and/or  property upon the exercise of any option or to accept shares on
         account of the purchase  price shall be subject to applicable  federal,
         state and local taxes and withholding requirements.

     (i) Limitations on Incentive Stock Options. Notwithstanding anything to the
         contrary herein set forth:

         (x)  The option  price under an Incentive  Stock  Option  granted to an
              individual  who,  at the time the  option is  granted,  owns stock
              possessing  more than ten  (10%)  percent  of the  total  combined
              voting power of all classes of stock of the Company  shall be 110%
              of the Fair Market Value of the stock at the time of grant and the
              term shall be for no more than five (5) years.
 
         (y)  The  aggregate  Fair Market  Value of shares with respect to which
              Incentive Stock Options are  exercisable  (under this Plan and all
              other  plans  of  the  Company  and  its  parent  and   subsidiary
<PAGE>
              companies)  for the first time by an optionee  during any calendar
              year shall not  exceed  $100,000,  applied to such  options in the
              order granted.  The aggregate Fair Market Value of shares of stock
              shall be determined as of the time the option with respect to such
              shares is granted.

         (z)  All options  granted as Incentive  Stock Options shall comply with
              subsection (b) of Section 422 of the Code.

     (j) Rights  as a  Stockholder.  An  optionee  shall  have  no  rights  as a
         Stockholder  with respect to any shares covered by his option until the
         issuance of a stock  certificate to him for such shares.  No adjustment
         shall be made for  dividends  or other rights for which the record date
         is prior to the issuance of such stock certificate, except as set forth
         in Section 7 herein.

     (k) Securities Act and Other Provisions. The instruments evidencing options
         may contain such other  provisions,  not inconsistent with the Plan, as
         the Board or the Committee deems advisable.  Among these provisions may
         be a requirement that an optionee  represent to the Company in writing,
         when an  option  is  granted,  and  when  he  purchases  shares  on its
         exercise,  that he is accepting such option, or purchasing such shares,
         unless they are then  covered by an  effective  registration  statement
         under the Securities Act of 1933, as amended  ("Securities  Act"),  for
         his own account for investment and not with a view to  distribution  of
         any such  shares.  The stock  certificate  issued upon  exercise of the
         option  may bear  such  legend  as  counsel  for the  Company  may deem
         advisable  in  connection  with  the Act.  The  Company  shall  have no
         obligation to register the shares issuable upon exercise of the options
         granted  hereunder  under the  Securities Act or to list such shares on
         any  quotation  service,  market or stock  exchange or to continue such
         registration or listing.

     7. Adjustments,  Termination and Acceleration of Options in Certain Events.
To the extent deemed equitable and appropriate by the Board or the Committee, in
its sole  discretion,  the  number,  price and class of shares  covered  by each
option and the total  number of shares  that may be sold under the Plan shall be
appropriately  adjusted  to reflect  any stock  dividend,  stock  split or share
combination  of the  Common  Stock  or  any  recapitalization  of  the  Company,
spin-off,  split-up,  rights  offering,  and in  any  merger  or  consolidation,
reorganization,  exchange of shares, or other change in the corporate  structure
("corporate change"),  liquidation or dissolution.  Any option granted under the
Plan may pertain to the  securities  and other  property which holders of Common
Stock   would  be   entitled   to  receive  in   connection   with  such  event.
Notwithstanding the foregoing, and unless the acquiring, surviving or continuing
corporation agrees in writing to assume the obligations under the option, in the
event of a dissolution or  liquidation  of the Company,  or a transfer of all or
substantially  all of its assets,  or a merger or  consolidation,  or  corporate
change,  the  Board or the  Committee  may,  in its sole  discretion,  terminate
options as of the effective  date of such event or accelerate  the date when any
or all installments of options shall become  exercisable.  Options granted under
the Plan or any other plan need not be treated  identically  by the Board or the
Committee  with  respect  to  termination,   acceleration,  or  assumption.  All
decisions  of the  Committee or the Board  hereunder  shall be final and binding
upon the option holder,  provided,  however,  no Incentive  Stock Option granted
pursuant to this Plan shall be adjusted or  accelerated  in a manner that causes
such  Incentive  Stock  Option to fail to qualify as an  Incentive  Stock Option
within the meaning of Section 422 of the Code.
<PAGE>
     8. Effect on Optionee's  Rights.  All payments and benefits  under the Plan
shall  constitute  special  benefits  and shall not affect the level of benefits
provided  to  or  received  by  any  optionee  (or  the  optionee's   estate  or
beneficiaries)  as part of any employee  benefit  plan of the Company.  The Plan
shall not be construed to affect in any way an optionee's rights and obligations
under any other plan  maintained by the Company on behalf of employees.  Nothing
in the Plan or in any option granted  pursuant to the Plan shall confer upon any
employee the right to continue in the  employment of the Company or restrict the
right of the Company to terminate the employment of any employee.

     9. Indemnification of Board and Committee. In addition to such other rights
of indemnification as they may have as members of the Board or as members of the
Committee,  the members of the Board and the Committee  shall be  indemnified by
the  Company  against  all costs and  expenses  reasonably  incurred  by them in
connection  with any claim,  action,  suit or proceeding to which they or any of
them may be or become a party by reason of any  action  taken or  failure to act
under or in connection  with the Plan,  or any option  granted  thereunder,  and
against all amounts paid by them in settlement thereof (provided such settlement
is  approved  by  legal  counsel  selected  by the  Company)  or paid by them in
satisfaction  of a judgment in any such  action,  suit or  proceeding,  except a
judgment based upon a finding of bad faith. Upon the making of any such claim or
commencement of any such action, suit or proceeding, a Board or Committee member
shall notify the Company in writing,  giving the Company an opportunity,  at its
own expense, to handle, settle or defend the same before such Board or Committee
member undertakes to handle, settle or defend the same on his own behalf.

     10.  Compliance with Rule 16b-3.  It is the Company's  intent that the Plan
comply in all respects  with Rule 16b-3 of the Exchange Act and any  regulations
promulgated  thereunder.  If any provision of this Plan is later found not to be
in compliance  with the Rule,  the provision  shall be construed so as to comply
therewith.

     11. Term and  Amendments of the Plan.  The Plan shall be effective upon the
date of  approval  of the Plan by the  Stockholders  of the  Company at the 1994
Annual Meeting  ("effective date") and shall, with the exception of options then
outstanding,  expire on the tenth (10th)  anniversary of the effective date, and
no option shall be granted  under the Plan after its  expiration.  The Board may
terminate or amend the Plan in any respect at any time provided that,  except as
provided  in  Section  7 of  the  Plan:  (a)  no  action  of  the  Board  or the
Stockholders  may alter or impair an  optionee's  rights  under any  outstanding
option  without his  consent,  and (b) without the  approval of the holders of a
majority of all outstanding shares of the Company entitled to vote thereon,  the
total number of shares that may be sold under the Plan may not be increased, the
provisions of Section 3, regarding  eligibility,  may not be modified, the price
at which shares may be purchased  pursuant to options may not be reduced and the
expiration date of the Plan may not be extended.

     12. Use of Proceeds.  Proceeds  from the sale of stock  pursuant to options
granted  under the Plan  shall  constitute  general  funds of the  Company.  

     13.  Pronouns.  Pronouns used in this Plan in the masculine shall be deemed
to include the feminine and pronouns in the singular  shall be deemed to include
the plural,  and the reverse,  as  appropriate  in the context where the pronoun
appears.
<PAGE>
REVOCABLE PROXY

                           UNIGENE LABORATORIES, INC.

        [ X ] PLEASE MARK VOTES AS IN THIS EXAMPLE

          PROXY SOLICITED BY THE BOARD OF DIRECTORS FOR ANNUAL MEETING

                                  JUNE 30, 1997

  The  undersigned  stockholder of Unigene  Laboratories,  Inc.  hereby appoints
Warren  P.  Levy,  Ronald  S.  Levy  and Jay  Levy,  and  each of  them,  as the
undersigned's  proxies (with the power of substitution),  to vote all the shares
of Common Stock of Unigene  Laboratories,  Inc. which the  undersigned  would be
entitled to vote at the Annual Meeting of Stockholders of Unigene  Laboratories,
Inc. to be held on June 30, 1997 at 11:00 A.M.,  Eastern  Daylight time, and any
adjournments thereof, on the following matters:

1. Election of directors

   Jay Levy, Ronald S. Levy,
   Warren P. Levy, Robert G. Ruark,
   Robert F. Hendrickson and George M. Weimer.

   [   ] FOR     [   ] WITHHOLD        [   ] FOR ALL EXCEPT


INSTRUCTION: To withhold authority to vote for any individual nominee, mark "For
All Except" and write that nominee's name in the space provided below.


- --------------------------------------------------------------------------------



2. Approval of amendment to the  Certificate  of  Incorporation  to increase the
number of authorized shares of Common Stock.

   [   ] FOR     [   ] AGAINST         [   ] ABSTAIN

3.  Approval of amendment to the Company's  1994  Employee  Stock Option Plan to
increase the total number of shares that may be sold.

   [   ] FOR     [   ] AGAINST         [   ] ABSTAIN

4.  Ratification  of the  appointment  of KPMG Peat  Marwick LLP as  independent
auditors of the Company.

   [   ] FOR     [   ] AGAINST         [   ] ABSTAIN

5. In  their  discretion  in the  transaction  of any  other  business  that may
properly come before such meeting.
<PAGE>
           The undersigned hereby revokes any proxy heretofore given.

          Please be sure to sign and date this Proxy in the box below. 

                     ---------------------------------------
                                      Date

                     ---------------------------------------
                             Stockholder sign above

                     ---------------------------------------

                          Co-holder (if any) sign above

    Detach above card, sign, date and mail in postage paid envelope provided. 

                           UNIGENE LABORATORIES, INC.

  This proxy will be voted in accordance with instructions  specified above, but
in the absence of any  instructions  will be voted "FOR" Items 1, 2, 3 and 4. If
any other  business is presented at the meeting,  the proxies are  authorized to
vote thereon in their discretion.

  The Board of Directors recommends a vote FOR Items 1, 2, 3 and 4 noted above.

  Please sign exactly as your name appears on this card.  If stock is registered
in the  names of two or more  joint  owners or  trustees,  each  joint  owner or
trustee  should sign this proxy.  When  signing as an  executor,  administrator,
trustee, guardian, agent or attorney, please give your full title as such.


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                     SIGN, DATE & MAIL YOUR PROXY CARD TODAY


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