QUIDEL CORP /DE/
SC 13D/A, 1996-09-24
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 5)*

                               QUIDEL CORPORATION
                                (Name of Issuer)

                          COMMON STOCK, $.001 PAR VALUE
                         (Title of Class of Securities)

                                    74838J101
                                 (CUSIP Number)

                               Marcia Casey, Esq.
                   John Hancock Mutual Life Insurance Company
                           Law Department, 55th floor
                                  P.O. Box 111
                              200 Clarendon Street
                           Boston, Massachusetts 02117
                                 (617) 572-9183
           (Name, Address and Telephone Number of Person Authorized to
                      Receive Notices and Communications)

                                  July 16, 1996
             (Date of Event which Requires Filing of this Statement)




If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box o.

Check the  following  box if a fee is being paid with the statement o. (A fee is
not required only if the reporting  person (1) has a previous  statement on file
reporting  beneficial  ownership  of more  than  five  percent  of the  class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7.)

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule  13d-1(a) for other  parties to whom copies are to be
sent.

* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                          Page 2 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           John Hancock Mutual Life Insurance Company: 
           IRS Identification No. 04-1414660

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) |_|
                                                                        (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Massachusetts
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       603,997
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                           8           SHARED VOTING POWER

                                       None

                           9           SOLE DISPOSITIVE POWER

                                       603,997

                          10           SHARED DISPOSITIVE POWER

                                       None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
           722,396,  including  (i) 517,712  shares held by John Hancock  Mutual
           Life  Insurance  Company and 86,285  shares held by the John  Hancock
           Mutual Life Insurance  Company Pension Plan, (ii) 97,545 shares owned
           through its indirect  wholly owned  subsidiary,  John Hancock Capital
           Growth  Management,  Inc.,  and (iii) 500 shares owned by, and 20,354
           shares held in a discretionary account of, Sutro & Co., Incorporated,
           an indirect  wholly-owned  broker-dealer  subsidiary  of John Hancock
           Mutual Life Insurance Company.

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
            SHARES*  |_|


13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           3.35%

14         TYPE OF REPORTING PERSON*

           IC
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 3 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           John Hancock Subsidiaries, Inc.:  IRS Identification No. 04-2687223

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) |_|
                                                                        (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       None
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                            8          SHARED VOTING POWER

                                       None

                            9          SOLE DISPOSITIVE POWER

                                       None

                           10          SHARED DISPOSITIVE POWER

                                       None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
           None except for (i) 97,545 owned  through its  indirect  wholly owned
           subsidiary,  John Hancock Capital Growth  Management,  Inc., and (ii)
           500 shares held by, and 20,354 shares held in a discretionary account
           of,  Sutro  &  Co.,   Incorporated,   a  wholly-owned   broker-dealer
           subsidiary of John Hancock Subsidiaries, Inc.

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
           SHARES*  |_|


13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.5%

14         TYPE OF REPORTING PERSON*

           CO/HC

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 4 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Hancock Venture Partners, Inc.:  IRS Identification No. 04-2765223

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) |_|
                                                                        (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       None
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                           8          SHARED VOTING POWER

                                      None

                           9          SOLE DISPOSITIVE POWER

                                      None

                          10          SHARED DISPOSITIVE POWER

                                      None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           None except for 97,545  shares owned  through its direct wholly owned
           subsidiary, John Hancock Capital Growth Management, Inc.

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
           SHARES*                                        |X|

           Excludes   500  shares   held  by,  and  20,354   shares  held  in  a
           discretionary  account  of,  Sutro & Co.,  Incorporated,  an indirect
           wholly-owned   subsidiary  of  John  Hancock  Mutual  Life  Insurance
           Company.

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.5%

14         TYPE OF REPORTING PERSON*

           CO/IA/HC

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 5 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           John Hancock Capital Growth Management, Inc.:  
           IRS Identification No. 04-2870816

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) |_|
                                                                        (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       97,545
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                            8          SHARED VOTING POWER

                                       None

                            9          SOLE DISPOSITIVE POWER

                                       97,545

                           10          SHARED DISPOSITIVE POWER

                                       None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           97,545 by virtue of its powers as a general partner of Gramercy Hill 
           Partners, L.P. and Capital Growth Partners, L.P.

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
           SHARES*                                           |X|

           Excludes   500  shares   held  by,  and  20,354   shares  held  in  a
           discretionary  account  of,  Sutro & Co.,  Incorporated,  an indirect
           wholly-owned   subsidiary  of  John  Hancock  Mutual  Life  Insurance
           Company.

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.5%

14         TYPE OF REPORTING PERSON*

           CO

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 6 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Gramercy Hill Partners, L.P.:  IRS Identification No. 13-3565834

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) |_|
                                                                        (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       10,654
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                            8          SHARED VOTING POWER

                                       None

                            9          SOLE DISPOSITIVE POWER

                                       10,654

                           10          SHARED DISPOSITIVE POWER

                                       None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           10,654

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
           SHARES*                                          |X|

           Excludes   500  shares   held  by,  and  20,354   shares  held  in  a
           discretionary  account  of,  Sutro & Co.,  Incorporated,  an indirect
           wholly-owned   subsidiary  of  John  Hancock  Mutual  Life  Insurance
           Company. 

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.05%

14         TYPE OF REPORTING PERSON*

           PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 7 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           John Hancock Capital Growth Fund III, L.P.:  
           IRS Identification No. 13-3570665

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a) |_|
                                                                       (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       None
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                            8          SHARED VOTING POWER

                                       None

                            9          SOLE DISPOSITIVE POWER

                                       None

                           10          SHARED DISPOSITIVE POWER

                                       None
11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           None

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
           SHARES*                                |X|

           Excludes   500  shares   held  by,  and  20,354   shares  held  in  a
           discretionary  account  of,  Sutro & Co.,  Incorporated,  an indirect
           wholly-owned   subsidiary  of  John  Hancock  Mutual  Life  Insurance
           Company.

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.00%

14         TYPE OF REPORTING PERSON*

           PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                          Page 8 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Capital Growth Partners, L.P.:  IRS Identification No. 04-2978138

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*          (a) |_|
                                                                      (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       86,891
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                           8           SHARED VOTING POWER

                                       None

                           9           SOLE DISPOSITIVE POWER

                                       86,891

                          10           SHARED DISPOSITIVE POWER

                                       None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           86,891 by virtue of its powers as a general partner of John Hancock 
           Capital Growth Fund IIB L.P.

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
           SHARES*                                            |X|

           Excludes   500  shares   held  by,  and  20,354   shares  held  in  a
           discretionary  account  of,  Sutro & Co.,  Incorporated,  an indirect
           wholly-owned   subsidiary  of  John  Hancock  Mutual  Life  Insurance
           Company.

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.4%

14         TYPE OF REPORTING PERSON*

           PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                   SCHEDULE 13D


CUSIP No. 74838J101                                          Page 9 of 16 Pages


1          NAME OF REPORTING PERSON
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           John Hancock Capital Growth Fund IIB, L.P.:  
           IRS Identification No. 04-3281630

2          CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*            (a) |_|
                                                                        (b) |X|


3          SEC USE ONLY


4          SOURCE OF FUNDS*

           OO

5          CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO 
           ITEMS 2(d) OR 2(e)     |_|


6          CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware
                            7          SOLE VOTING POWER
         NUMBER OF
          SHARES                       86,891
       BENEFICIALLY
         OWNED BY
           EACH
         REPORTING
          PERSON
           WITH
                           8           SHARED VOTING POWER

                                       None

                           9           SOLE DISPOSITIVE POWER

                                       86,891

                         10            SHARED DISPOSITIVE POWER

                                       None

11         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           86,891

12         CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 
           SHARES*                                  |X|

           Excludes   500  shares   held  by,  and  20,354   shares  held  in  a
           discretionary  account  of,  Sutro & Co.,  Incorporated,  an indirect
           wholly-owned   subsidiary  of  John  Hancock  Mutual  Life  Insurance
           Company.

13         PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           0.4%

14         TYPE OF REPORTING PERSON*

           PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                        Page 10 of 16 Pages


THIS  AMENDMENT  RESTATES AND AMENDS A SCHEDULE 13D AND THE  AMENDMENTS  THERETO
WITH RESPECT TO THE  SECURITIES  AND ISSUER  NAMED IN ITEM 1 BELOW.  THE INITIAL
SCHEDULE 13D WAS FILED WITH THE SECURITIES  AND EXCHANGE  COMMISSION ON OR ABOUT
FEBRUARY 8, 1991.

Item 1.  Security and issuer.

         This statement  relates to the common stock,  $.001 par value per share
(the  "Common  Stock"),  of Quidel  Corporation,  a  Delaware  corporation  (the
"Issuer"). The principal executive office of the Issuer is 10165 McKellar Court,
San Diego, California 92121.


Item 2.  Identity and background.

         This  statement  is filed  pursuant  to Reg.  ss.13(d)-1(f)(1)  by John
Hancock Mutual Life Insurance  Company,  a  Massachusetts  mutual life insurance
company  ("Hancock"),  John Hancock  Subsidiaries,  Inc., a Delaware corporation
(the "Holding  Company"),  Hancock Venture  Partners,  Inc.,  which was formerly
named "John Hancock Venture Capital Management, Inc." ("Venture Partners"), John
Hancock Capital Growth Management, Inc., a Delaware corporation (the "Management
Company"),  Gramercy Hill Partners,  L.P. ("GHLP"),  John Hancock Capital Growth
Fund III, L.P. ("Fund III"),  Capital Growth  Partners,  L.P.  ("CGLP") and John
Hancock Capital Growth Fund IIB, L.P. ("Fund IIB").

         The principal offices and the principal business address of Hancock and
the Holding Company are P.O. Box 111, John Hancock Place, Boston,  Massachusetts
02117.  The  principal  office  and the  principal  business  address of Venture
Partners, GHLP, CGLP, Fund III and Fund IIB are One Financial Center, 44th floor
Boston, Massachusetts 02111. The principal office and principal business address
of the  Management  Company are 1140 Taylor Street,  San  Francisco,  California
94108.

         Hancock is a life insurance  company in the United  States,  offering a
wide  variety  of  individual  and group  life and  health  insurance  policies,
individual annuities and group pension products and other financial services.

         The Holding  Company is a  wholly-owned  subsidiary of Hancock and owns
various  operating  subsidiaries of Hancock.  Venture Partners is a wholly-owned
subsidiary of the Holding  Company and a registered  investment  adviser and, on
May 3, 1994,  acquired  all the capital  stock of the  Management  Company.  The
Management  Company,  a  wholly-owned  subsidiary  of  Venture  Partners  and an
indirect wholly-owned  subsidiary of the Holding Company, is principally engaged
in the business of furnishing investment, management and administrative services
for Fund III and Fund IIB and for other funds of a similar nature.

         The names,  business  addresses and present  principal  occupations  or
employment of the current executive  officers and directors of Hancock are shown
on Exhibit B to this Schedule 13D.  Except as set forth on such Exhibits,  there
has been no change in the  information  previously  filed  with  respect  to the
officers and directors of the entities named above.



<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 11 of 16 Pages


         During the last five  years,  neither  Hancock,  the  Holding  Company,
Venture Partners or the Management Company nor any of their respective executive
officers or directors has been (i) convicted in a criminal proceeding (excluding
traffic  violations  or  similar  misdemeanors)  or (ii)  was a party to a civil
proceeding of a judicial or administrative body of competent jurisdiction and as
a result of such  proceeding  was or is subject to a  judgment,  decree or final
order  enjoining  future  violations of, or prohibiting or mandating  activities
subject  to,  federal or state  securities  laws or finding any  violation  with
respect to such laws.


Item 3.  Source and amount of funds or other consideration.

         On March 4, 1983,  Venture Partners  purchased 31,915 shares of Class B
preferred  stock of Quidel  Corporation  ("Old  Quidel") for a purchase price of
$750,002. On October 5, 1984, Venture Partners purchased 5,400 shares of Class C
preferred  stock of Old Quidel for a purchase price of $108,000.  On October 29,
1985,  Venture Partners purchased 4,101 shares of Class D preferred stock of Old
Quidel for a purchase price of $102,526.  On August 18, 1986,  Venture  Partners
purchased  11,000  shares of Class E  preferred  stock and  warrants to purchase
2,200 shares of common stock of Old Quidel for a purchase price of $107,800.  On
January 19, 1988,  Venture Partners  purchased 9,846 shares of Class F preferred
stock of Old Quidel for a purchase price of $113,230, and 1,106 shares of common
stock of Old Quidel for a purchase price of $1,770. The source of funds for each
purchase was  partnership  contributions  from the John Hancock  Venture Capital
Fund. In 1989, Old Quidel split half of its operations into another corporation,
LaJolla  Pharmaceutical.  Thus, of the amounts originally received by Old Quidel
from Venture Partners for the purchase of the securities  described above,  only
half may be deemed to have remained with Old Quidel.

         On January 31, 1991, Old Quidel merged with Monoclonal Antibodies, Inc.
The  surviving  corporation  is the Issuer.  At the time of the merger,  the Old
Quidel securities held by Venture Partners were converted into 146,420 shares of
Common Stock of the Issuer and warrants to purchase 2,465 shares of Common Stock
of the Issuer.

         On January 31, 1991, Fund III purchased  616,413 shares of Common Stock
and Fund IIB purchased 50, 252 shares of Common Stock, for an aggregate purchase
price of $1,999,995.  Fund III also received warrants to purchase 616,413 shares
and Fund IIB received  warrants to purchase 50,252 shares at no additional cost.
The source of the funds was partnership contributions.

         On March 5,  1991,  Venture  Partners  completed  the  disposal  of its
146,420  shares of Common Stock and warrants to purchase  2,465 shares of Common
Stock.

         On July 1, 1993,  Fund III exchanged a promissory note of the Issuer in
the principal  amount of $3,698,488  for 902,070 Shares of Common Stock and Fund
IIB exchanged its note of $301,512 for 73,539 shares of Common Stock.  The notes
were outstanding  pursuant to a Note Purchase  Agreement dated as of January 31,
1991 (the "Note Purchase Agreement"), under which Fund III and Fund IIB had made
unsecured subordinated loans to the issuer in the amount of $4,000,000.

         As part of the  arrangements  relating to such  exchange,  up to 40,000
additional  shares were issuable pro rata to Fund III and Fund II if the average
market  price of the Common  Stock over the 180 day period  between July 1, 1993
and December 31, 1993 was below $4.50 per share. Eight hundred shares would be 


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 12 of 16 Pages


issued, up to such 40,000 shares maximum, for each $.01 by which $4.50 per share
exceeded such coverage market price. Such adjustment would not be made if either
Fund II B or Fund III sold shares of Common Stock during such period without the
Issuer's consent.

         In a series of  transactions  in December,  1995, Fund III and Fund IIB
sold 203,400 and 16,600  shares,  respectively,  of the Common Stock.  All sales
were open-market transactions effected by brokers on the Nasdaq Stock Market, on
which the Issuer's Common Stock is traded.

         Fund III and Fund IIB held  Warrants  of the  Issuer  (the  "Warrants")
allowing them to acquire  shares of Common Stock (the  "Warrant  Shares") of the
Issuer.  Pursuant to the operation of an  antidilution  provision  governing the
Warrants,  the number of Warrant  Shares that could be acquired was increased in
January, 1996 by a total of 10,168 shares, 9,402 of which Fund III had the right
to  acquire  9,402  and the  remaining  766 of which  Fund IIB had the  right to
acquire.

         On or about January 29, 1996, the Management Company,  acting on behalf
of Fund III and Fund IIB,  sold Warrants to acquire  277,387 and 22,613  Warrant
Shares beneficially owned by Fund III and Fund IIB, respectively. The sale was a
privately   negotiated   transaction  between  the  Management  Company  and  an
institutional investor.

         In addition,  in a series of transactions  from January 2, 1996 through
February  14,  1996,  Fund  III and  Fund  IIB sold  99,900  and  8,100  shares,
respectively,  of the  Common  Stock.  All sales were  open-market  transactions
effected by brokers on the Nasdaq Stock  Market,  on which the  Issuer's  Common
Stock is traded.

         In a series of  transactions  from  February  15, 1996  through May 28,
1996, Fund III and Fund IIB sold 149,800 and 12,200 shares, respectively, of the
Common Stock, at prices ranging from $6.00 to $6.25 per share.

         On or about July 16, 1996, the Management Company,  acting on behalf of
Fund III, made a  distribution  of Common Stock of the Issuer to the limited and
general partners of Fund III, including Hancock and the John Hancock Mutual Life
Insurance Company Pension Plan, distributing 1,065,383 shares of Common Stock to
the partners of Fund III. On or about July 16,  1996,  the  Management  Company,
acting on behalf of Fund IIB, authorized the sale of the remaining 86,891 shares
of Common Stock beneficially owned by Fund IIB.


Item 4.  Purpose of transaction.

         The  acquisitions and dispositions of Common Stock and related warrants
reported  above were in each case the  result of  investment  decisions  made by
Venture Partners,  or by the Management Company acting on behalf of Fund III and
Fund IIB.  All sales were  open-market  transactions  effected by brokers on the
Nasdaq Stock Market,  on which the Issuer's Common Stock is traded.  Neither any
of the sales nor the  distribution  was made with the  purpose  or the effect of
changing  the control of the  Issuer,  and none was in  connection  with or as a
participant in any transaction having such purpose or effect.



<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                        Page 13 of 16 Pages


Item 5.  Interest in securities of the issuer.

         (a) As a result of the sales and  distributions  reported hereby,  Fund
III no longer  owns any shares of Common  Stock.  Pursuant  to the  distribution
reported  hereby,  GHLP owns 10,654 shares of Common Stock (the "GHLP  Shares").
Fund IIB owns 86,891 shares of Common Stock (the "Fund IIB Shares") and CGLP, by
virtue of its powers as a general  partner of Fund IIB, may be deemed to own the
Fund IIB Shares. The Management Company, as general partner of GHLP, and Venture
Partners,  of which the Management Company is a direct  subsidiary,  may also be
deemed to own the GHLP Shares and the Fund IIB Shares. In addition, Sutro & Co.,
Incorporated,  an indirect wholly owned subsidiary of Hancock and a wholly owned
subsidiary  of the Holding  Company  and a  registered  broker-dealer  under the
Securities  Exchange Act of 1934 ("Sutro"),  owns 500 shares of Common Stock and
holds an  additional  20,354  shares  (the  "Sutro  Shares")  of the Issuer in a
discretionary account. The Holding Company, of which both the Management Company
and Sutro are subsidiaries,  may be deemed to own both the GHLP Shares, the Fund
IIB Shares and the Sutro Shares, a total of 118,399 shares. Hancock owns 603,997
shares of Common  Stock,  including  517,712  shares  held by Hancock and 86,285
shares  distributed to the John Hancock Mutual Life  Insurance  Company  Pension
Plan, over which Hancock has voting and dispositive  power, and Hancock may also
be deemed to own the GHLP Shares, the Fund IIB Shares and the Sutro Shares.

         Each reporting  person other than Fund III (i.e.  Hancock,  the Holding
Company,  Venture  Partners,  the Management  Company,  Fund IIB, CGLP and GHLP)
holds, both individually and together with the other reporting  persons,  shares
of  Common  Stock  representing  less  than  5% of  the  Issuer's  Common  Stock
outstanding at March 31, 1996.

         (b)  GHLP  and  the  Management   Company,   through  its   partnership
relationship  to GHLP,  have sole  power to vote or direct  the vote of and sole
power to dispose of or direct the  disposition of the GHLP Shares.  CGLP and the
Management Company, through its partnership relation to CGLP, have sole power to
dispose or direct the  disposition of the Fund IIB Shares.  Hancock has the sole
power to vote or direct  the vote of and sole  power to dispose of or direct the
disposition  of the 517,712  shares  that it owns by reason of the  distribution
reported  hereby and the 86,285  shares  held by the John  Hancock  Mutual  Life
Insurance  Company  Pension  Plan.  Except  through their  respective  ownership
interests in the Management  Company,  none of Hancock,  the Holding  Company or
Venture  Partners  has any power to vote or direct  the vote of to dispose of or
direct the disposition of the GHLP Shares.

         (c)  See response 5(a) above.

         (d)  Not applicable.

         (e) Each  reporting  person  ceased to own more than 5% of the Issuer's
outstanding  Common Stock on or about July 16, 1996, the date when  distribution
of the shares held by Fund III was authorized.




<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 14 of 16 Pages


Item 6. Contracts, arrangements, understandings or relationships with respect to
        securities of the issuer.

         Pursuant to the Note Purchase Agreement  described in Item 3 above, the
Management  Company  made an  unsecured  subordinated  loan to the issuer in the
amount  of  $4,000,000.  The  Note  Purchase  Agreement  and the  rights  of the
Management  Company  thereunder  terminated  upon  exchange of the notes  issued
thereunder for shares of Common Stock.

Item 7.  Material to be filed as exhibits.

         The following documents are filed as exhibits to this statement:

         Exhibit A:        Agreement  concerning joint filing of Schedule 13D
                           (Omitted--previously  filed  with  the  Schedule  13D
                           amended hereby).

         Exhibit B:        Officers and Directors of Hancock (Amended Exhibit B 
                           attached hereto).

         Exhibit C:        Officers  and  Directors  of the Holding  Company
                           (Omitted--previously  filed  with  the  Schedule  13D
                           amended hereby).

         Exhibit D:        Officers  and   Directors  of  Venture   Partners
                           (Omitted--previously  filed  with  the  Schedule  13D
                           amended hereby).

         Exhibit E:        Officers and Directors of the  Management  Company
                           (Omitted--previously  filed  with  the  Schedule  13D
                           amended hereby).

         Exhibit F:        General  Partners  of  GHLP  (Omitted--previously
                           filed with the Schedule 13D amended hereby).

         Exhibit G:        General  Partners  of  CGLP  (Omitted--previously
                           filed with the Schedule 13D amended hereby).

         Exhibit H:        Note Purchase Agreement (Omitted--previously filed
                           with the Schedule 13D amended hereby).

         Exhibit I:        Exchange Agreement (Omitted--previously filed with
                           the Schedule 13D amended hereby).


<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                        Page 15 of 16 Pages




                                   SIGNATURES

         After reasonable inquiry and to the best of their knowledge and belief,
the  undersigned  certify that the  information  set forth in this  statement is
true, complete and correct.

                                    JOHN HANCOCK MUTUAL LIFE
                                      INSURANCE COMPANY


Dated:  September 6, 1996           By:/s/John T. Farady
                                       Name: John T. Farady
                                       Title: Senior Vice President & Treasurer


                                    JOHN HANCOCK SUBSIDIARIES, INC.


Dated:  September 6, 1996           By:/s/John T. Farady
                                       Name: John T. Farady
                                       Title:   Treasurer


                                    HANCOCK VENTURE PARTNERS, INC.


Dated:  September 10, 1996          By:/s/Martha D. Vorlicek
                                       Name: Martha D. Vorlicek
                                       Title: Vice President & Treasurer


                                    JOHN HANCOCK CAPITAL GROWTH
                                      MANAGEMENT, INC.


Dated:  September 10, 1996          By:/s/Martha D. Vorlicek
                                       Name:  Martha D. Vorlicek
                                       Title: Treasurer


                                    GRAMERCY HILL PARTNERS, L.P.

                                    By: John Hancock Capital Growth 
                                          Management, Inc.,
                                        General Partner


                                    By:/s/Martha D. Vorlicek
Dated:  September 10, 1996             Name: Martha D. Vorlicek
                                       Title: Treasurer



<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 16 of 16 Pages


                                    JOHN HANCOCK CAPITAL GROWTH FUND III, L.P.
                                    By:  Gramercy Hill Partners, L.P., 
                                            General Partner
                                          By:  John Hancock Capital Growth 
                                               Management, Inc., General Partner

                                    
Dated:  September 10, 1996          By:/s/Martha D. Vorlicek   
                                       Name: Martha D. Vorlicek
                                       Title: Treasurer     
   
                                    
                                    CAPITAL GROWTH PARTNERS, L.P.
                                    By: John Hancock Capital Growth 
                                          Management, Inc., General Partner


Dated:  September 10, 1996          By:/s/Martha D. Vorlicek   
                                       Name: Martha D. Vorlicek
                                       Title: Treasurer  
      

                                    JOHN HANCOCK CAPITAL GROWTH FUND IIB, L.P.
                                    By:  Capital Growth Partners, L.P., 
                                          General Partner
                                         By:  John Hancock Capital Growth 
                                               Management, Inc., General Partner


Dated:  September 10, 1996          By:/s/Martha D. Vorlicek   
                                       Name: Martha D. Vorlicek
                                       Title: Treasurer        





<PAGE>


                                  SCHEDULE 13D


CUSIP No. 74838J101                                        Page 17 of 16 Pages


EXHIBIT B
<TABLE>
<CAPTION>

                   JOHN HANCOCK MUTUAL LIFE INSURANCE COMPANY


                                                                             Position with John Hancock
                                           Business or                       Mutual Life Insurance Company
     Name                               Residential Address                  and Present Principal Occupation
     ----                               -------------------                  --------------------------------
<S>                                    <C>                                  <C>

Foster L. Aborn                         John Hancock Place                    Vice Chairman of John Hancock
                                        P.O. Box 111                          Mutual Life Insurance Company
                                        Boston, MA  02117

Samuel W. Bodman                        75 State Street                       Director of John Hancock Mutual
                                        Boston, MA  02109-1806                Life Insurance Company; Chairman
                                                                              and Chief Executive Officer of
                                                                              Cabot Corporation

Joan T. Bok                             25 Research Drive                     Director of John Hancock Mutual
                                        Westborough, MA  01581                Life Insurance Company; Chairman
                                                                              of Board of New England Electric
                                                                              System

I. MacAllister Booth                    549 Technology Square                 Director of John Hancock Mutual
                                        Cambridge, MA  02139                  Life Insurance Company;
                                                                              Chairman, President and Chief
                                                                              Executive Officer of Polaroid
                                                                              Corporation

William L. Boyan                        John Hancock Place                    Director, President and Chief
                                        P.O. Box 111                          Operations Officer of John Hancock
                                        Boston, MA  02117                     Mutual Life Insurance Company,
                                                                              Inc.

Dr. Randolph W. Bromery                 263 Alden Street                      Director of John Hancock Mutual
                                        Springfield, MA  01109                Life Insurance Company; President
                                                                              of Springfield College

Stephen L. Brown                        John Hancock Place                    Chairman of the Board and Chief
                                        P.O. Box 111                          Executive Officer of John Hancock
                                        Boston, MA  02117                     Mutual Life Insurance Company,
                                                                              Inc.

John M. Conners, Jr.                    200 Clarendon Street                  Director of John Hancock Mutual
                                        Boston, MA  02116                     Life Insurance Company; President,
                                                                              CEO and Director of Hill, Holiday,
                                                                              Connors, Cosmopulos, Inc.

David F. D'Alessandro                   John Hancock Place                    Director of John Hancock Mutual
                                        P.O. Box 111                          Life Insurance Company; Senior
                                        Boston, MA  02117                     Executive Vice President and John
                                                                              Hancock Mutual Life Insurance Co.



<PAGE>

<CAPTION>

                                  SCHEDULE 13D


CUSIP No. 74838J101                                         Page 18 of 16 Pages

                                                                             Position with John Hancock
                                           Business or                       Mutual Life Insurance Company
     Name                               Residential Address                  and Present Principal Occupation
     ----                               -------------------                  --------------------------------
<S>                                    <C>                                  <C>
Dr. Kathleen Foley Feldstein            147 Clifton Street                    Director of John Hancock Mutual
                                        Belmont, MA  02178                    Life Insurance Company; President
                                                                              of Economics Studies, Inc.

Lawrence K. Fish                        One Citizens Plaza                    Director of John Hancock Mutual
                                        Providence RI  02903-1339             Life Insurance Company;
                                                                              Chairman, President and CEO of
                                                                              Citizens Financial Group, Inc.

Nelson S. Gifford                       50 Federal Street - Ste 900           Director of John Hancock Mutual
                                        Boston, MA  02110-2509                Life Insurance Company; Former
                                                                              Chairman and CEO of Dennison
                                                                              Mfg. Corporation

Michael C. Hawley                       Prudential Tower Bldg.                Director of John Hancock Mutual
                                        Boston, MA  02199                     Life Insurance Company; President
                                                                              of The Gillette Company

John F. Magee                           Acorn Park                            Director of John Hancock Mutual
                                        Cambridge, MA  02140-2390             Life Insurance Company; Chairman
                                                                              of Arthur D. Little, Inc.

E. James Morton                         1st Floor, Clarendon Bldg.            Director of John Hancock Mutual
                                        P.O. Box 111                          Life Insurance Company; Former
                                        Boston, MA  02117                     Chairman and CEO of John
                                                                              Hancock Mutual Life Insurance
                                                                              Company

Bruce Skrine                            John Hancock Place                    Vice President, Counsel and
                                        P.O. Box 111                          Secretary of John Hancock Mutual
                                        Boston, MA  02117                     Life Insurance Company, Inc.

Richard F. Syron                        86 Trinity Place                      Director of John Hancock Mutual
                                        New York, NY  10016                   Life Insurance Company; Chairman
                                                                              and Chief Executive Officer of
                                                                              American Stock Exchange

Robert J. Tarr, Jr.                     27 Boylston Street                    Director of John Hancock Mutual
                                        Chestnut Hill, MA  02167              Life Insurance Company; President
                                                                              and Chief Executive Officer of
                                                                              Harcourt General, Inc.

C. Vincent Vappi                        240 Sidney Street                     Director of John Hancock Mutual
                                        Cambridge, MA  02139                  Life Insurance Company; Former
                                                                              Chairman and Chief Executive
                                                                              Officer of Vappi & Company, Inc.


</TABLE>




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