QUIDEL CORP /DE/
3, 1999-07-19
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 3

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

1.  Name and Address of Reporting Person

    Larry N. Feinberg
    c/o Oracle Investment Management, Inc.
    712 Fifth Avenue
    45th Floor
    New York, New York  10019

2.  Date of Event Requiring Statement (Month/Day/Year)

    July 14, 1999

3.  IRS Number of Reporting Person
    (Voluntary)

4.  Issuer Name and Ticker or Trading Symbol

    Quidel Corp.
    QDEL

5.  Relationship of Reporting Person(s) to Issuer (Check all
    applicable)

    ( ) Director (X) 10% Owner ( ) Officer (give title
    below) ( ) Other
    (specify below)

6.  If Amendment, Date of Original (Month/Day/Year)

7.  Individual or Joint/Group Filing (Check Applicable Line)

   (X) Form filed by One Reporting Person
   ( ) Form filed by More than One Reporting Person


     Table I -- Non-Derivative Securities Beneficially Owned

1. Title of Security 2. Amount of    3. Ownership   4. Nature of Indirect
                        Securities      Form:          Beneficial Ownership
                        Beneficially    Direct(D) or
                        Owned           Indirect(I)




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Common Stock           200,000              (D)
Common Stock         2,300,700 +            (I)        General Partner,
                                                       Principal of Investment
                                                       Manager or Trustee.



















































                                2



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            Table II -- Derivative Securities Beneficially Owned

<TABLE>
<S>            <C>             <C>                    <C>             <C>              <C>
1.Title of     2.Date Exer-    3.Title and Amount     4. Conver-      5. Ownership     6. Nature of
  Derivative     cisable and     of Securities           sion or         Form of          Indirect
  Security       Expiration      Underlying              Exercise        Derivative       Beneficial
                 Date            Derivative Security     Price of        Security:
                 Ownership
                 (Month/Day/      ---------------        Deri-           Direct(D) or
                 Year)           Title   Amount or       vative          Indirect (I)
               ---------------           Number of       Security
               Date    Expira-           Shares
               Exer-   tion
               cisable Date

                                            NOT APPLICABLE
</TABLE>

Explanation of Responses:

+ The Reporting Person disclaims beneficial ownership of these
securities except to the extent of his pecuniary interest
therein.

SIGNATURE OF REPORTING PERSON


/s/ Larry N. Feinberg
___________________________
    Larry N. Feinberg


July 19, 1999





















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