QUIDEL CORP /DE/
8-K, 1999-12-15
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>


                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                 ---------------

                                    FORM 8-K

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934



       Date of report (Date of earliest event reported): December 7, 1999


                               QUIDEL CORPORATION
               (Exact Name of Registrant as Specified in Charter)



            Delaware                    0-10961               94-2573850
(State or Other Jurisdiction of       (Commission           (IRS Employer
         Incorporation)               File Number)        Identification No.)



              10165 McKeller Court
                 San Diego, CA                               92121
    (Address of Principal Executive Offices)               (Zip Code)




       Registrant's telephone number, including area code: (858) 552-1100



                                 Not Applicable
          (Former Name or Former Address, if Changed Since Last Report)


<PAGE>


         ITEM 2. ACQUISITION OR DISPOSITION OF ASSETS.

         As previously reported, Quidel Corporation entered into an Asset Sale
Agreement dated as of November 26, 1999 with Dade Behring Marburg GmbH, (Dade
Behring"), a German corporation, for the purchase of Dade Behring's
Rapignost-Registered Trademark- Urine Test Strip Business. The asset purchase
closed on December 7, 1999, effective as of November 30, 1999.

         The purchase price was US $5,750,000, payable US $5,000,000 at Closing,
US $500,000 twelve months later and US $250,000 payable twenty-four months after
Closing upon successful completion of certain milestones defined in the
Transitional Manufacturing Assistance Agreement between the parties. In addition
to the aggregate purchase price for the assets, Quidel agreed to pay Dade
Behring a percentage of the combined global sales of Rapignost for five years
after the Closing, up to a maximum of US $3,000,000. The funds used for the
purchase price payment at closing came from Quidel's existing line of credit
with the Bank of America.

         The acquired assets include: Dade Behring's inventory of Rapignost test
strips, product manufacturing equipment, information and know-how, trademarks,
vendor and customer contracts, distributor agreements, and assignments of
certain license agreements. Pursuant to the terms of the Transitional
Manufacturing and Transfer Assistance Agreement, Dade Behring will continue to
manufacture Rapignost for Quidel for up to two years after closing.

         The Rapignost test fits into Quidel's existing product line,
distribution system and strategic direction. Quidel believes that Rapignost will
add to Quidel's sales at lower cost than introducing a new product.

         ITEM 7. FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND
EXHIBITS.

         (c)      EXHIBITS.

         10.5     Form of Asset Sale Agreement - Rapignost-Registered Trademark-
                  Urine Strip Business

         The Schedules and Exhibits to the Asset Purchase Agreement are omitted
from this filing in accordance with Item 601(b)(2) of Regulation S-K. Quidel
agrees to supply any omitted Schedule or Exhibit to the Commission upon receipt
of a request by the Commission, subject to a reservation of its right to request
confidential treatment as to certain information under the Freedom of
Information Act, Privacy Act and the Commission's confidential treatment rules
at the time.



                                       2
<PAGE>


         The omitted Schedules are captioned:

         Schedule 1.1.1        Machinery and Equipment List UTS Business Marburg
         Schedule 1.1.2        Inventory
         Schedule 1.1.6        Product Registrations
         Schedule 3.1.4        Litigation Claims
         Schedule 3.1.6        Violations of Applicable Laws
         Schedule 3.1.7        Contracts Material to the Operation of the
                               Business Which Require Third Party
                               Consents or Approvals
         Schedule 3.1.8        Contracts Requiring Consent for Assignment
         Schedule 5.1          Allocation of Purchase Price

         In addition to the Schedules, there are four Exhibits to the Asset Sale
Agreement:

         Exhibit A - Form of Proprietary Rights Agreement
         Exhibit B - Form of Transitional Manufacturing and Transfer Assistance
                           Agreement
         Exhibit C - Form of Distribution Agreement
         Exhibit D - Form of Lease Agreement




                                       3
<PAGE>


                                    SIGNATURE

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                         QUIDEL CORPORATION



Date:    December 15, 1999               By:     /s/ CHARLES J. CASHION
                                               ---------------------------------
                                               Charles J. Cashion
                                               Senior Vice President,
                                               Corporate Operations,
                                               Chief Financial Officer and
                                               Secretary



                                  EXHIBIT INDEX


<TABLE>
<CAPTION>

    Exhibit
     Number                                    Description
     ------                                    -----------
    <S>           <C>

    10.5          Asset Sale Agreement - Rapignost-Registered Trademark-Urine
                  Test Strip Business

</TABLE>




                                       4





<PAGE>


                                                                    Exhibit 10.5


                              ASSET SALE AGREEMENT



           RAPIGNOST -Registered Trademark- URINE TEST STRIP BUSINESS



This Asset Sale Agreement (this "Agreement") is made and entered into as of
November 26, 1999 ("Effective Date") by and between:

         Quidel Deutschland GmbH, a company formed under the laws of Germany
         with its registered office at Czernyring 22/10, 69115 Heidelberg, and

         Quidel Corporation, a Delaware corporation with its registered office
         at 10165 McKellar Court, San Diego 92121, California, USA (collectively
         the "Purchaser");

                                       and

         Dade Behring Marburg GmbH, a German corporation, with its registered
         office at Emil von Behring Str. 76, 35041 Marburg, Germany (the
         "Seller").

The Purchaser and the Seller are sometimes referred to herein individually as a
"Party" and collectively as the "Parties". Unless otherwise indicated,
capitalized terms used but not defined prior to the first usage herein are
defined in Article XIII.

WHEREAS, the Seller owns and operates the Rapignost -Registered Trademark- Urine
Test Strip Business, as defined herein and referred to herein as the "Business";

WHEREAS, the Purchaser desires to purchase from the Seller and the Seller
desires to sell to the Purchaser certain assets of the Business, and the Seller
desires to transfer to the Purchaser and the Purchaser desires to assume from
the Seller certain liabilities of the Seller, in each case upon the terms and
conditions set forth herein;

NOW, THEREFORE, in consideration of the mutual covenants and agreements made
herein, and of the mutual benefit derived hereby, the Parties, intending to be
legally bound, agree as set forth herein.



                                    ARTICLE I
             PURCHASE AND SALE OF ASSETS; ASSUMPTION OF LIABILITIES

1.1      PURCHASED ASSETS. On and subject to the terms and conditions set forth
         in this Agreement (except as set forth in section 1.1.5), the Seller
         hereby sells, assigns, transfers, and delivers to the Purchaser, or a
         designated Affiliate of Purchaser, (and shall cause its Affiliates to
         sell, assign, transfer, and deliver), and the Purchaser, or a
         designated Affiliate of Purchaser, hereby purchases from the Seller,
         all of the Seller's right, title, and interest in and to the following
         (collectively, the "Purchased Assets"):


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                                                                    Page 1 of 25
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1.1.1    MACHINERY AND EQUIPMENT. The machinery and equipment set forth on
         Schedule 1.1.1 hereto.

1.1.2    INVENTORY. The Inventory of the Seller is as listed on Schedule 1.1.2
         (net of any reserves for obsolescence) saleable to customers in the
         normal course of the Business, and not obsolete, deteriorated or
         unusable under standard quality control procedures (the "Inventory").
         The inventory located at Seller's facilities in Marburg and Dortmund
         shall be transferred at Closing to the Purchaser pursuant to the terms
         of Section 2.4 below. For inventory held at other locations, Seller may
         sell such inventory until January 31, 2000, except that Seller and/ or
         its Affiliates may retain inventory in jurisdictions where Seller
         and/or its Affiliates will continue to act as distributors for the
         Business after the Closing.

1.1.3    SELLER'S CONTRACT RIGHTS AND OBLIGATIONS. All sales orders, purchase
         orders (except for those purchase orders issued to Seller by Purchaser
         or Purchaser's Affiliates), contracts, distribution agreements,
         development agreements, consulting agreements, OEM license agreements,
         or any other agreements, and the like (subject to the appropriate
         consent) which are necessary for the operation of the Business as now
         being conducted, including those set forth on Schedule 3.1.8, (the
         "Contracts").

1.1.4    BUSINESS RECORDS. All business records pertinent to the Business as
         conducted as of the Closing, confidential or otherwise (subject to
         third party confidentiality restrictions or legally required consents),
         to the extent such records are necessary for the operation of the
         Business, including laboratory notebooks and prosecution files if
         relating to the Proprietary Rights which are to be assigned to the
         Purchaser pursuant to the Proprietary Rights Agreement, tax records (to
         the extent they relate specifically to the Business), market
         information, sales aids, customer and supplier lists, manufacturing
         procedures and records, protocols and the like. The Seller hereby
         reserves the right to retain a copy of such records for its use subject
         to the confidentiality provision of Section XII hereof and the
         non-competition provision of Section 7.1.2 hereof.

1.1.5    PROPRIETARY RIGHTS. The proprietary rights transferred or licensed to
         Purchaser or an Affiliate of Purchaser pursuant to the Proprietary
         Rights Agreement entered into by and between Quidel Corporation and the
         Seller as of the Closing Date.

1.1.6    PRODUCT REGISTRATIONS. All product registrations held by Seller or its
         Affiliates including all 510k's or similar registrations set forth on
         Schedule 1.1.6.

1.2      EXCLUDED ASSETS. Notwithstanding anything expressed or implied to the
         contrary in this Agreement, the Purchased Assets shall not include any
         assets of the Seller or its Affiliates whatsoever other than the
         specific assets expressly identified in Section 1.1. Without limiting
         the generality of the foregoing, the term "Excluded Assets" as used in
         this Agreement shall include, without limitation, cash, accounts
         receivable, notes receivable, prepaid taxes, expenses or allowances for
         the post-closing period, interests in insurance policies, real
         properties, facilities, Rapimat or similar diagnostic instruments,
         computer systems (including voice mail, freight related systems,
         software and order entry systems), chose of action, and the use of the
         Dade Behring or Syva names, except as expressly set forth in the
         Proprietary Rights Agreement.


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                                                                    Page 2 of 25
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1.3      ASSUMPTION OF CERTAIN LIABILITIES. On and subject to the terms and
         conditions set forth herein, the Purchaser hereby assumes and is liable
         for the following obligations of the Seller (the "Assumed
         Liabilities"):

1.3.1    POST-CLOSING PERFORMANCE OBLIGATIONS. All liabilities and obligations
         of the Seller to the extent they arise out of or relate to the
         ownership, use or operation of the Business or the Purchased Assets
         after the Closing, including, but not limited to, all liabilities and
         obligations under the Contracts which either arise after the Closing or
         which are to be performed after the Closing, including but not limited
         to obligations to sell products and to develop products.

1.3.2    INFRINGEMENT CLAIMS. All liabilities and obligations which arise out of
         or relate to any claim or action (regardless of when such claim or
         action arises) arising out of the operation or ownership of the
         Business or the Purchased Assets after the Closing including any and
         all claims alleging, with respect to the Proprietary Rights to be
         transferred pursuant to the Proprietary Rights Agreement, infringement,
         misappropriation or other conflict with the Proprietary Rights of any
         third party.

1.4      EXCLUDED LIABILITIES. Other than as set forth in Section 1.3 above, the
         Purchaser shall not assume or become liable for (and, thus "Assumed
         Liabilities" shall not include) any other liabilities of the Seller
         (the "Excluded Liabilities), including ,without limitation, any
         liability relating to a license and manufacturing agreement between
         Seller and Jugoremedija, a Yugoslav company.



                                   ARTICLE II
                               THE PURCHASE PRICE

2.1      THE PURCHASE PRICE. For purposes of this Agreement, in addition to
         Purchaser's assumption of liabilities as provided in Section 1.3, the
         "Purchase Price" for the Purchased Assets, for the covenant not to
         compete provided in Section 7.1.2, and for all other rights and
         obligations contemplated hereunder shall be equal to United States
         Dollars Five Million Seven Hundred Fifty Thousand (USD 5,750,000)
         payable as follows:

2.1.1    An initial cash payment of United States Dollars Five Million (USD
         5,000,000) payable in immediately available funds at the Closing.

2.1.2    United States Dollars Five Hundred Thousand (USD 500,000) to be paid in
         immediately available funds twelve (12) months after the Closing;
         provided, however, that in respect of such funds Purchaser shall
         deliver to Seller at Closing a bank guarantee from a major United
         States Financial Institution payable to Seller upon the one year
         anniversary of the Closing Date for the full amount thereof. The terms
         of such guarantee shall be reasonably satisfactory to Seller and shall
         include, without limitation, that in the event of a default in payment
         of such amount, Seller shall have the option to exercise the guarantee
         without being obligated to first exhaust all remedies against
         Purchaser.

2.1.3    United States Dollars Two Hundred Fifty Thousand (USD 250,000) to be
         paid in immediately available funds twenty-four (24) months after the
         Closing; provided, however, that such funds shall only be paid to the
         Seller upon successful completion of the milestones defined in the
         Transitional Manufacturing and Transfer Assistance Agreement ("TMA");

2.2      ADDITIONAL PAYMENT. In addition to the payments set forth in Section
         2.1 above, Purchaser shall pay to Seller an amount equal to three
         percent (3%) of the combined annual global sales of the products of
         Business for a period of five (5) years from Closing, and up to


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                                                                    Page 3 of 25
<PAGE>


         a maximum of United States Dollars Three Million (USD 3,000,000). The
         first two (2) years of royalties shall only be paid to the Seller upon
         successful completion of the milestones defined in the TMA. For
         purposes of calculating annual sales each such annual period shall
         begin on January 1 and conclude on the following December 31 (except of
         the first period, which shall begin on December 1, 1999 and end on
         December 31, 2000). All annual payments shall be due and payable on or
         before the following February 28. Simultaneous with the annual payment,
         Purchaser shall provide Seller with a report, to be prepared at
         Purchaser's own expense, detailing sales within such period; provided,
         however, that the names of customers need not be listed in such
         reports. If the Parties disagree about the contents of such report,
         they shall use good faith efforts to resolve such disagreement,
         including if necessary the appointment of an independent auditor from
         one of the big five accounting firms that is not providing services to
         either party at the time of such appointment; failing which, such
         dispute shall be subject to arbitration as provided in this Agreement.

2.3      CLOSING.

         (a)      The consummation of the transactions contemplated by this
                  Agreement (the "Closing") shall take place on November 30,
                  1999, or at such other time as may be mutually agreed upon by
                  the Parties (the "Closing Date").

         (b)      The Seller and the Purchaser agree that title in all tangible
                  Purchased Assets shall be conveyed to the Purchaser with the
                  effect as of Closing. At Closing, Seller shall execute and
                  deliver to Purchaser the deeds, patents, trademarks and other
                  assignments and such other instruments of transfer in agreed
                  form, as shall be effective to vest in Purchaser good title,
                  to all of the Purchased Assets. The Purchaser shall be granted
                  immediate possession in all tangible Purchased Assets through
                  delivery to the Purchaser at their respective locations on the
                  Closing. To the extent that tangible Purchased Assets are not
                  in the immediate possession of the Seller, the granting of
                  possession is substituted by the assignment of the claim for
                  conversion against the immediate possessor. To the extent that
                  the Purchaser does not gain possession of individual tangible
                  Purchased Assets because of their delivery is not possible or
                  expedient for practical reasons, the granting of possession
                  shall be substituted by the agreement between Seller and
                  Purchaser that these Purchased Assets shall be held by the
                  Seller for the benefit of the Purchaser as of the Closing and
                  the possession will be granted to the Purchaser as soon as
                  practicably possible.

         (c)      To the extent tangible Purchased Assets are subject to rights
                  of retention or have been transferred to third parties for
                  security purposes, Seller shall, irrespective of possible
                  claims of the Purchaser for a breach of warranty arising
                  therefrom, assign to the Purchaser its respective expectant
                  rights (ANWARTSCHAFTSRECHTE) and all claims and rights it has
                  relating to these Purchased Assets including all rights of
                  return or repossession.

         (d)      If any of the conditions precedent to Purchaser's obligation
                  to close this transaction set forth in Section 8.2 below are
                  not satisfied on the scheduled Closing Date and the Purchaser
                  does not wish to waive such condition(s), Purchaser may in its
                  sole discretion, upon notice to Seller at least twenty four
                  (24) hours prior to the Closing Date, reschedule the Closing
                  for another date (which must be a business day) not later than
                  three (3) days after the conditions precedent have been waived
                  or satisfied. All proceedings to take place at the Closing
                  shall be deemed to take place simultaneously, and delivery
                  shall not be considered to have been made until all such
                  proceedings have been completed. The Closing shall be deemed
                  to have taken place at 11:59 p.m., C.E.T. on the Closing Date.


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                                                                    Page 4 of 25
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2.4      INVENTORY ADJUSTMENT. On the Closing Date, there will be an inventory
         adjustment based upon the difference between the book value of the
         Average Inventory of Seller located in Marburg and Dortmund, Germany
         and the book value of the Closing Date Inventory conducted by Purchaser
         at Seller's facilities in Marburg and Dortmund, Germany.

2.4.1    AVERAGE INVENTORY. The term "Average Inventory" shall mean the six (6)
         month average month end inventory balance of Seller of Inventory
         located in Marburg and Dortmund, Germany for the months ending March
         through August 1999.

2.4.2    CLOSING DATE INVENTORY. The term "Closing Date Inventory" shall mean
         the inventory located at Seller's facilities in Marburg and Dortmund,
         Germany on the Closing Date.

2.4.3    DETERMINATION. The inventory adjustment shall be determined on the
         Closing Date. The costs and expenses associated with determining the
         inventory adjustment shall be borne by Purchaser. If the book value of
         the Closing Date Inventory exceeds the book value of the Average
         Inventory, then Purchaser shall pay to Seller an amount equal to the
         difference between the book value of the Closing Date Inventory and the
         book value of the Average Inventory. If the book value of the Average
         Inventory is greater than the book value of the Closing Date Inventory,
         then Seller shall pay to Purchaser the difference between such values.

2.4.4    PAYMENTS. All payments made in accordance with this Section 2.4 shall
         be paid by a wire transfer of available funds in United States currency
         made to an account designated by the Party to receive such payment. Any
         amount not in dispute under this Section shall be considered due and
         payable immediately upon receipt of notice of said amounts being due
         and such payment shall be made within five (5) business days. Any
         amount in dispute shall be due and payable within ten (10) days after
         the resolution of the dispute pursuant to the terms of this Agreement.
         Each such payment due to Seller or Purchaser shall include interest on
         the amount paid at ten percent (10%) (compounded annually) from the
         Closing until the date of payment.



                                   ARTICLE III
                         REPRESENTATIONS AND WARRANTIES

3.1      REPRESENTATIONS AND WARRANTIES OF THE SELLER. The Seller represents and
         warrants to the Purchaser as of the Closing, except to the extent a
         representation and warranty relates to a specified date, as follows:

3.1.1    CORPORATE STATUS. The Seller is a corporation duly organized, validly
         existing and in good standing (as such concept is defined in the
         relevant jurisdiction(s)) under the laws of Germany, with all requisite
         corporate power and authority to own, lease and operate its properties
         and to carry on its business as now being conducted.

3.1.2    AUTHORIZATION. The Seller has the corporate power and authority to
         execute and deliver the Transactional Documents to which it is a party,
         to perform fully its obligations hereunder and thereunder, and to
         consummate the transactions contemplated hereby and thereby. The
         execution and delivery by the Seller of the Transactional Documents to
         which it is a party, and the consummation of the transactions
         contemplated hereby and thereby, have been duly authorized by all
         requisite corporate action of the Seller. The Seller has duly executed
         and delivered this Agreement, and each of the other Transactional
         Documents to which it is a party. Assuming this Agreement and the other
         Transactional Documents constitute valid and binding obligations of
         Purchaser, each of this Agreement and the other Transactional Documents
         is a legal, valid and binding obligation of Seller, enforceable against
         it in accordance with its respective terms, except as such
         enforceability may be limited by (a) applicable insolvency, bankruptcy,
         reorganization, moratorium or other similar


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                                                                    Page 5 of 25
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         laws affecting creditors' rights generally, or (b) applicable equitable
         principles (whether considered in a proceeding at law or in equity).

3.1.3    NO CONFLICTS. The execution, delivery and performance by the Seller of
         this Agreement and the other Transactional Documents and the
         consummation of the transactions contemplated hereby and thereby will
         not (a) violate or conflict with any provision of the Certificate of
         Incorporation or By-laws (or equivalent organizational documents) of
         the Seller, each as amended to date; or (b) constitute a violation of,
         or be in conflict with, or constitute or create a default with or
         without the giving of notice or the lapse of time or both with respect
         to any property of the Seller (including without limitation any of the
         Purchased Assets), other than a violation, conflict or default which
         would not have a Material Adverse Effect, pursuant to (i) any contract,
         agreement or instrument to which the Seller is a party or by which it
         or any of its properties (including without limitation any of the
         Purchased Assets) is bound or to which it or any of such properties is
         subject, or (ii) to Seller's knowledge, any Applicable Law.

3.1.4    LITIGATION, ETC. Except as set forth on Schedule 3.1.4, no action,
         suit, proceeding or investigation is pending or to the knowledge of
         Seller threatened, relating to or affecting any of the Purchased Assets
         or which questions the validity of the Transactional Documents or
         challenges any of the transactions contemplated hereby or thereby
         except to the extent such action, suit, proceeding or investigation
         would result in a loss or liability to the Business of less than United
         States Dollars Ten Thousand (USD 10,000), said sum to be assessed in
         good faith by the Seller.

3.1.5    PURCHASED ASSETS CONDITION. Except as set forth in Schedule 3.1.5, the
         Purchased Assets are all the assets that are necessary to conduct the
         Business as currently conducted.

3.1.6    COMPLIANCE WITH LAWS: GOVERNMENTAL APPROVALS. Except as disclosed in
         Schedule 3.1.6 attached hereto, since June 1, 1998, the Seller has not
         received any notice with respect to the Business alleging any violation
         of Applicable Law, except for such violation which would not result in
         a penalty greater than United States Dollars Ten Thousand (USD 10,000),
         but including those, which could have a Material Adverse Effect, such
         sum to be assessed in good faith by the Seller. The Seller holds all
         Governmental Approvals necessary for the conduct of the Business, as
         now conducted, except where the failure to obtain such Governmental
         Approvals would not have a Material Adverse Effect. Except as disclosed
         in Schedule 3.1.6, all such Governmental Approvals are in full force
         and effect, and to Seller's knowledge their continuing effectiveness
         will not be materially adversely affected by any of the transactions
         contemplated hereby, and the Business is in compliance in all material
         respects with each such Governmental Approval, except where such
         non-compliance would not have a Material Adverse Effect.


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3.1.7    ASSETS. Except as set forth on Schedule 3.1.7, the Seller is the legal
         and beneficial owner of, and has good and valid record title, to all of
         the Purchased Assets, and has the full right to sell, convey, transfer,
         assign, license and deliver the Purchased Assets, without the need to
         obtain the consent or approval of any third party. Except as set forth
         on Schedule 3.1.7, all of the Purchased Assets are free and clear of
         any security interests, liens, claims, charges, options, mortgages,
         debts, leases (or subleases), conditional sales agreements, title
         retention agreements, encumbrances of any kind, material defects as to
         title or restrictions against the transfer or assignment thereof
         (collectively, "Encumbrances").

3.1.8    CONTRACTS. Except for (i) this Agreement, the other Transactional
         Documents and the contracts set forth on the other Schedules to this
         Agreement, and (ii) any purchase order for goods or services in the
         ordinary course of business, Schedule 3.1.8 attached hereto lists all
         of the material written contracts ("Contracts") to which the Seller is
         a party as of the date of this Agreement. For the avoidance of doubt,
         the Contracts relating to proprietary rights are listed in the
         respective schedules of the Proprietary Rights Agreement, and the
         representations and warranties in the Proprietary Rights Agreement
         shall apply to such proprietary rights Contracts. The Seller has
         delivered to the Purchaser true, correct and complete copies of all
         such Contracts, together with all modifications thereof and is not in
         breach of any of the provisions of any such Contract, nor, to the
         knowledge of Seller, is any other party to any such Contract in default
         thereunder. Except as set forth on Schedule 3.1.8, the Seller has not
         received notice since June 1, 1998 of any default under any of the
         foregoing Contracts that has not been cured. The Seller has in all
         material respects performed all obligations required to be performed by
         it to date under each such Contract.

3.1.9    BROKERS, FINDERS, ETC. All negotiations relating to this Agreement and
         the transactions contemplated hereby have been carried on without the
         participation of any Person acting on behalf of the Seller or Purchaser
         in such manner as to give rise to any valid claim against the Purchaser
         or Seller for any brokerage or finder's commission, fee or similar
         compensation.

3.1.10   MACHINERY AND EQUIPMENT; INSTRUMENTS. All machinery and equipment
         listed on Schedule 1.1.1 is in good operating condition and repair,
         subject to normal wear and tear.

3.1.11   ORDINARY COURSE. During the past three months from the date hereof, the
         amount of products of the Business that the Seller has transferred to
         its distributors has been consistent with the Seller's past practice
         and policies and has been in the ordinary course of business.

3.2      REPRESENTATIONS AND WARRANTIES OF THE PURCHASER. The Purchaser
         represents and warrants to the Seller as of the date hereof and, except
         to the extent a representation and warranty relates to a specified
         date, as of the Closing as follows:

3.2.1    CORPORATE STATUS. Quidel Deutschland GmbH and Quidel Corporation are
         companies duly organized under the laws of Germany and Delaware
         respectively, validly existing and in good standing (as such concept is
         defined in the relevant jurisdiction(s)) under the laws of all
         jurisdictions in which each of them conducts business, and each of them
         has all requisite corporate power and authority to own, lease and
         operate its properties and to carry on its business as now being
         conducted.

3.2.2    AUTHORIZATION. The Purchaser has the power and authority to execute and
         deliver the Transactional Documents to which it is a party, to perform
         fully its obligations hereunder and thereunder, and to consummate the
         transactions contemplated hereby and thereby. The execution and
         delivery by the Purchaser of the Transactional Documents to which it is
         a party, and the consummation of the transactions contemplated hereby
         and thereby, have been duly authorized by all requisite corporate
         action of the Purchaser. The Purchaser has


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                                                                    Page 7 of 25
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         duly executed and delivered this Agreement and each of the other
         Transactional Documents to which it is a party.

         This Agreement and the other Transactional Documents constitute valid
         and binding obligations of Seller, each of this Agreement and the other
         Transactional Documents is a legal, valid and binding obligation of the
         Purchaser, enforceable against it in accordance with its respective
         terms, except as such enforceability may be limited by (a) applicable
         insolvency, bankruptcy, reorganization, moratorium or other similar
         laws affecting creditors' rights generally, or (b) applicable equitable
         principles (whether considered in a proceeding at law or in equity).

3.2.3    NO CONFLICTS. The execution, delivery and performance by the Purchaser
         of the Transaction Documents, and the consummation of the transactions
         contemplated hereby and thereby, do not and will not conflict with or
         result in a violation of or a default under (with or without the giving
         of notice or the lapse of time or both) (a) any Applicable Law
         applicable to the Purchaser, (b) the Certificate of Incorporation or
         By-laws (or equivalent organizational documents) of the Purchaser, or
         (c) any material contract, agreement or other instrument to which the
         Purchaser is a party or by which the Purchaser is bound.

3.2.4    LITIGATION. There is no action, claim, suit, judgement, injunction,
         order or decree pending, or to the Purchaser's Knowledge threatened,
         against the Purchaser that relates to the transactions contemplated by
         this Agreement, nor are there agreements or envisaged agreements which
         are capable of impacting the Purchaser's ability to fulfil its
         obligations under the present Agreement. In the event that any such
         agreement comes into effect, or is intended to come into effect
         following the Closing, the Purchaser shall inform the Seller without
         delay of the same.

3.2.5    BROKERS, FINDERS, ETC. All negotiations relating to this Agreement and
         the transactions contemplated hereby have been carried on without the
         participation of any Person acting on behalf of the Purchaser in such
         manner as to give rise to any valid claim against the Seller for any
         brokerage or finder's commission, fee or similar compensation.



                                   ARTICLE IV
                              ADDITIONAL AGREEMENTS

4.1      ADDITIONAL AGREEMENTS. Simultaneously herewith, Seller and Purchaser
         shall enter into that certain Transitional Manufacturing and Transfer
         Assistance Agreement, that certain Lease Agreement with respect to the
         manufacturing facility in Marburg, and that certain Proprietary Rights
         Agreement. The Distribution Agreements for the agreed upon territories
         will be negotiated in good faith by both parties and consummated no
         later than sixty (60) days following the Closing Date, provided, and
         the parties hereby acknowledge that the terms of the distribution
         agreement attached hereto as Exhibit C will be substantially the terms
         incorporated into the final distribution agreements for the agreed upon
         territories, provided however for the territories of Japan and Brazil
         the parties agree that they will independently negotiate the specific
         issues of transfer price, term of the agreement, margins and quotas
         (and in Japan, the issues of labeling and minimum purchase orders).



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                                                                    Page 8 of 25
<PAGE>


                                    ARTICLE V
                                      TAXES

5.1      ALLOCATION OF PURCHASE PRICE. The Purchaser and the Seller shall
         allocate the Purchase Price (including the amount of liabilities
         assumed by the Purchaser, as determined at the Closing) among the
         Purchased Assets as set forth on Schedule 5.1 attached hereto, and such
         Schedule shall be used by the Parties in preparing all Tax Returns. The
         Purchaser and the Seller shall each file their respective tax returns
         in accordance with this Section 5.1, with its federal Income Tax Return
         for its taxable period that includes the Closing. All allocations made
         pursuant to this Section 5.1 shall be binding upon the Parties and upon
         each of their successors and assigns, and the Parties shall report the
         transactions contemplated by this Agreement in accordance with such
         allocations.

5.2      SALES AND TRANSFER TAXES. All transfer, documentary, sales, use, stamp,
         registration and other Taxes and fees, including any penalties and
         interest thereon (collectively, "Transfer Taxes") incurred in
         connection with this Agreement shall be split equally between Seller
         and Purchaser. However, Purchaser shall be solely responsible for value
         added taxes. Purchaser shall pay the Transfer Taxes when due and will
         file all necessary Tax Returns and other documentation with respect to
         such Transfer Taxes and, if required, by applicable law, the Seller
         will join in the execution of any such Tax Returns and other
         documentation. Seller shall pay to Purchaser Seller's share of the
         transfer taxes no later than ten (10) days prior to the date when such
         Transfer Taxes are due to be paid by Purchaser. Purchaser must provide
         documents evidencing the amount to be paid to the tax authorities and
         the date when such payment is due, all in a manner that is reasonably
         acceptable to Seller.

5.3      CO-OPERATION ON TAX MATTERS. The Purchaser and the Seller shall
         co-operate fully, as and to the extent reasonably requested by the
         other Party, in connection with any audit, litigation or other
         proceeding with respect to Taxes relating to the Business. Such
         co-operation shall include the retention and (upon the other Party's
         request) the provision of records and information which are reasonably
         relevant to any such audit, litigation or other proceeding and making
         employees available on a mutually convenient basis to provide
         additional information and explanation of any material provided
         hereunder. The Purchaser and the Seller agree (i) to retain all books
         and records with respect to Tax matters relating to the Business
         pertinent to the Seller relating to any taxable period beginning before
         the Closing until the expiration of the statute of limitations (and, to
         the extent notified by the Purchaser or the Seller, any extensions
         thereof) of the respective taxable periods, and to abide by all record
         retention agreements entered into with any taxing authority, and (ii)
         to give the other Party reasonable written notice prior to
         transferring, destroying or discarding any such books and records and,
         subject to respective confidentiality requirements of the Parties, if
         the other Party desires to take possession of such books and records
         such Party may make copies of such books and records.



                                   ARTICLE VI
                          COVENANTS PENDING THE CLOSING

       During the period from the date of this Agreement until the Closing Date
       or the earlier termination of this Agreement, Seller agrees (except as
       expressly contemplated by this Agreement or to the extent that Purchaser
       shall otherwise consent in writing) as follows:

6.1    ORDINARY COURSE. Seller shall carry on the Business in the usual, regular
       and ordinary course, in substantially the same manner as heretofore
       conducted, and use all reasonable efforts consistent with past practice
       and policies to preserve its present Business operations, keep available
       the services of the Business' key employees (other than employees


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                                                                    Page 9 of 25
<PAGE>


       terminated for cause) and preserve its relationships with customers,
       suppliers, distributors and others having business dealings with it
       relating to the Business.

6.2    NO SOLICITATION. Seller shall not, directly or indirectly, through any
       employee, agent or representative (including without limitation
       investment bankers, attorneys, accountants and consultants), or
       otherwise:
       (i)   solicit, initiate or further the submission of proposals or
             offers from, or enter into any agreement with, any firm,
             corporation, partnership, association, group or other person
             or entity, individually or collectively (including without
             limitation any managers, employees or independent contractors
             of the Seller or any of its Affiliates), other than Purchaser
             (a "Third Party"), relating to any acquisition or purchase of
             all or a material portion of the Purchased Assets;
       (ii)  participate in any discussions or negotiations regarding the
             acquisition or purchase of all or a material portion of the
             Purchased Assets, or furnish to any Third Party any confidential
             information with respect thereto; or
       (iii) otherwise cooperate in any way with, or assist or participate in,
             facilitate or encourage, any effort or attempt by any Third Party
             to do or seek to do any of the foregoing with the respect to the
             Purchase Assets.

       Seller shall promptly notify Purchaser in writing if any such proposal or
       offer, or any inquiry or contact with any Third Party with respect
       thereto, is made, and shall in any such notice, set forth in reasonable
       detail the identity of the Third Party, the terms and conditions of any
       proposal and any other information requested of them by the Third Party
       or in connection therewith.

       Seller shall immediately cease and cause to be terminated any existing
       activities, discussions or negotiations with any Third Party conducted
       prior to the date of this Agreement with respect to any of the foregoing.

6.3    APPROVALS AND CONSENTS. Unless Purchaser is required by law to be
       responsible for any of the following, Seller will obtain all necessary
       governmental and third party approvals and consents required in order to
       authorize and approve this Agreement and the other Transactional
       Documents, to consummate the sale of the Purchased Assets to Purchaser
       pursuant to this Agreement, and to transfer and assign all of the
       Contracts set forth on Schedule 3.1.8.. Purchaser shall provide
       reasonable assistance to the Seller in the Seller's effort to obtain such
       consents.



                                   ARTICLE VII
                         OTHER COVENANTS AND AGREEMENTS

7.1      COVENANTS AND AGREEMENTS OF THE SELLER

7.1.1    FURTHER ASSURANCES. After the Closing, the Seller shall from time to
         time execute and deliver such additional instruments, documents,
         conveyances or assurances and take such other actions as shall be
         necessary, or as may be reasonably requested by the Purchaser, to
         confirm and assure the transfer of the rights and obligations provided
         for in this Agreement and render effective the consummation of the
         transactions contemplated hereby and thereby.

7.1.2    NON-COMPETITION. The Seller hereby expressly covenants and agrees that
         for a period of five (5) years from and after the Closing, the Seller
         will not directly or indirectly manufacture, distribute, or sell any
         urine test strips in the field of human in vitro urine diagnostics by
         the determination of Bilirubin, Urobilinogen, Ketones, Ascorbic acid,
         Glucose, Albumin (Protein), Blood, Ph-value, Nitrite, Leucocytes,
         Specific Gravity and Amylease in urine, provided however, that Seller
         may manufacture, distribute and sell, any


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                                                                   Page 10 of 25
<PAGE>


         urine test strips to be used in drug abuse testing, therapeutic drug
         monitoring (including immunosuppressive drug monitoring), adulteration
         testing, cardiac testing, hormone testing, and microbiological testing.
         Notwithstanding the foregoing and subject to the following sentence,
         Seller may acquire or be acquired by (including, without limitation,
         any purchase or sale of stock or assets, merger, joint venture or
         alliance) a business that otherwise would violate the foregoing
         restriction and thereafter develop such business, as long as no more
         than four percent (4%) of the annual income of such business (measured
         as of the date of such transaction) is in businesses which violate the
         foregoing restriction. Notwithstanding the foregoing, the following
         shall apply:

         a)  The Seller may acquire or be acquired by Bayer AG, Roche AG,
             and/ or their successor companies;

         b)  the Seller may acquire or be acquired by a business which violates
             any of the restrictions stated above so long as the Seller shall
             commence procedures to divest itself of the competing manufacturing
             operations of such business within three (3) months after such
             acquisition and complete such divestiture within (2) years after
             such acquisition.

         c)  The non competition restrictions on Seller included in this section
             7.1.2 shall not apply in Brazil and/ or Japan should either of the
             distributorship agreements to be negotiated between Purchaser and
             Seller's affiliates in Brazil and Japan, be terminated by Purchaser
             for reasons other than cause, as defined under such distributorship
             agreements.

         d)  If it is ever held that the restrictions placed on Seller by this
             Section 7.1.2 are too onerous and are not necessary for the
             protection of Purchaser, the Parties agree that any court of
             competent jurisdiction shall be requested by both Parties to reduce
             the duration or scope hereof, or delete specific words or phrases,
             such that in its reduced form such provision will then be
             enforceable and will be enforced.

7.1.3    PRE-CLOSING ACCESS TO INFORMATION. Between the date of this Agreement
         and the Closing Date, at Purchaser's expense and risk, the Seller shall
         (i) give Purchaser and its authorized representatives reasonable access
         during normal business hours to all plants, offices, warehouses and
         other facilities used in the Business and to all contracts, internal
         reports, data processing files and records, federal, state, local and
         foreign tax returns and records, commitments, books, records and
         affairs of the Seller directly relating to the Business, whether
         located on the premises of the office facilities of the Seller or at
         another location, (ii) permit Purchaser to make such reasonable
         inspections as it may require, (iii) cause its officers to furnish
         Purchaser such financial, operating, technical and product data and
         other information with respect to the Business as Purchaser from time
         to time may reasonably request, including without limitation financial
         statements and schedules, and (iv) assist and cooperate with Purchaser
         in the development of integration and transition plans for
         implementation by Purchaser following the Closing Date; provided,
         however, that no investigation pursuant to this Section 7.1.3 shall
         affect or be deemed to modify any representation or warranty made by
         the Seller herein.

         Seller shall give Purchaser prompt notice of any material breach of any
         of its covenants hereunder or the occurrence of any event that is
         reasonably likely to cause any of its representations and warranties
         hereunder to become incomplete or untrue in any material respect.

7.2      COVENANTS AND AGREEMENTS OF THE PURCHASER.

7.2.1    FURTHER ASSURANCES. After the Closing, the Purchaser shall from time to
         time execute and deliver such additional instruments, documents,
         conveyances or assurances and take such


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                                                                   Page 11 of 25
<PAGE>


         other actions as shall be necessary, or otherwise reasonably requested
         by the Seller, to confirm and assure the obligations of the Purchaser
         provided for in this Agreement and render effective the consummation of
         the transactions contemplated hereby and thereby.

7.2.2    POST-CLOSING ACCESS AND INFORMATION

         (a)  After the Closing, the Purchaser will (and will cause its
              accountants, counsel, consultants, employees and agents to)
              give the Seller, and its accountants, counsel, consultants,
              employees and agents, full access, during normal business
              hours and upon reasonable notice, to all employees, documents,
              records, work papers and information with respect to all of
              such Person's properties, assets, books, contracts,
              commitments, reports and records relating specifically to the
              Business or the Purchased Assets, as the Seller may from time
              to time reasonably request in order to prepare the Seller's
              income and other tax returns. In addition, the Purchaser shall
              permit the Seller to make copies at its own expense of any of
              the above-mentioned documents, records and information for
              such purposes.

         (b)  The Purchaser will retain all books and records relating to the
              Business or any of Seller's predecessors in interest for at least
              seven (7) years or for such longer period as may be required by
              applicable law.

         (c)  In the event that, in connection with the consummation of the
              transactions contemplated hereby, the Purchaser obtains, after the
              Closing, any documents, records or information that, instead of
              relating to the Purchased Assets, relate to the Seller or any of
              its Affiliates or any of their respective operations or
              businesses, the Purchaser shall (i) promptly notify the Seller of
              that fact, (ii) promptly upon Seller's request return such
              document, record or information to the Seller, (iii) not use any
              such document, record or information in any way, and (iv) keep the
              content of such document, record or information confidential in
              all respects.

         (d)  In the event that the Seller finds, after the Closing, any
              documents, records or information that should have been provided
              to the Purchaser pursuant to Section 1.1.4 hereof, the Seller
              shall (i) promptly notify the Purchaser of that fact, and (ii)
              promptly upon Purchaser's request provide such document, record or
              information to the Purchaser; provided, however, that the Seller
              may retain a copy of such document, record or information for its
              use subject to the confidentiality provision of Section XII hereof
              and the non-competition provision of Section 7.1.2 hereof.


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                                                                   Page 12 of 25
<PAGE>


7.3      EXPENSES; BROKERS.

7.3.1    EXPENSES. Except as otherwise provided herein, the Seller, on the one
         hand, and the Purchaser, on the other hand, shall bear their respective
         expenses, costs and fees (including attorneys' and accountants' fees)
         in connection with the transaction contemplated hereby, including the
         preparation, execution and delivery of this Agreement and the other
         Transactional Documents and compliance herewith (the "Transaction
         Expenses"), whether or not the transactions contemplated hereby are
         consummated.

7.3.2    BROKERS. Without limiting the generality of Section 7.3.1 above, each
         party shall indemnify the other Party against any and all liability and
         claims for any brokers' or finders' fees arising with respect to
         brokers or finders retained or engaged by such Party.



                                  ARTICLE VIII
               CONDITIONS PRECEDENT TO OBLIGATIONS OF THE PARTIES

8.1      CONDITIONS TO THE OBLIGATIONS OF PURCHASER AND SELLER. The respective
         obligations of Purchaser and Seller set forth in this Agreement shall
         be subject to the satisfaction on or prior to the Closing Date of the
         following conditions, unless waived by each such Party:

         (a)  LEGAL ACTION. No temporary restraining order, preliminary
              injunction or permanent injunction or other order preventing
              the consummation of the transactions contemplated by this
              Agreement shall have been issued by any federal, state or
              foreign court or other governmental or regulatory authority
              and remain in effect, and no litigation seeking the issuance
              of such an order or injunction, or seeking substantial damages
              against Purchaser or the Seller if the transactions
              contemplated by this Agreement are consummated, shall be
              pending which, in the good faith judgment of the Seller and
              Purchaser, have a reasonable probability of resulting in such
              order, injunction or substantial damages. In the event any
              such order or injunction shall have been issued, each Party
              agrees to use its reasonable efforts to have any such
              injunction lifted.

         (b)  STATUTES. No federal, state, local or foreign statute, rule or
              regulation shall have been enacted which would make the
              consummation of the transactions contemplated by this
              Agreement illegal.

8.2      FURTHER CONDITIONS TO THE OBLIGATIONS OF PURCHASER. The obligations of
         Purchaser set forth in this Agreement are subject to the satisfaction
         on or prior to the Closing Date of the following conditions, unless
         waived by Purchaser:

         (a)  REPRESENTATIONS AND WARRANTIES. The representations and
              warranties of the Seller set forth in this Agreement shall be
              true and correct in all material respects as of the date of
              this Agreement and as of the Closing Date as though made at
              and as of the Closing Date; and Purchaser shall have received
              a certificate (the "Compliance Certificate") dated the Closing
              Date to the foregoing effect signed by an authorized officer
              of the Seller.


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                                                                   Page 13 of 25
<PAGE>


         (b)  PERFORMANCE OF OBLIGATIONS OF OTHER PARTIES. Seller shall have
              satisfied all of the conditions set forth in this Section 8.2
              and performed in all material respects all obligations
              required to be performed by it under this Agreement prior to
              the Closing Date, and the Compliance Certificate shall include
              a statement to such effect.

         (c)  NO LITIGATION. Since the date hereof, there shall not have
              been instituted and be continuing or threatened against the
              Seller, any claim, action or proceeding related to the
              Business or the Purchased Assets which, if adversely
              determined, could, individually or in the aggregate,
              reasonably be expected to have a Material Adverse Effect.

         (d)  CONSENTS AND APPROVALS. All waivers, licenses, agreements
              permits, consents, approvals or authorizations of third
              parties or governmental agencies or any modifications or
              amendments to existing agreements with third parties required
              to be obtained by Seller or Purchaser shall have been obtained
              and shall be in full force and effect and without conditions
              or limitations which unreasonably restrict the ability of the
              Parties hereto to carry out the transactions contemplated
              hereby and Purchaser shall have been furnished with
              appropriate evidence, reasonably satisfactory to it and its
              counsel, of the granting of same.

         (e)  DILIGENCE REVIEW. Purchaser shall be satisfied, in its sole
              discretion, with the result of its due diligence investigation
              of the Business, including Purchaser's review of the
              financial, regulatory and operational aspects of the Business.

         (f)  EXECUTION OF RELATED AGREEMENTS. Seller shall have executed
              the Proprietary Rights Agreement with Purchaser or an
              Affiliate of Purchaser substantially in the form attached
              hereto as Exhibit A and the Transitional Manufacturing
              Agreement with Purchaser substantially in the form attached
              hereto as Exhibit B. In addition, Seller shall execute the
              Lease Agreement with Purchaser substantially in the form
              attached hereto as Exhibit D.

8.3      FURTHER CONDITIONS TO THE OBLIGATIONS OF SELLER. The obligations of
         Seller set forth in this Agreement are subject to the satisfaction on
         or prior to the Closing Date of the following conditions, unless waived
         by Seller:

         (a)  REPRESENTATIONS AND WARRANTIES. The representations and
              warranties of Purchaser set forth in this Agreement shall be
              true and correct in all material respects as of the date of
              this Agreement and as of the Closing Date as though made at
              and as of the Closing Date, except as otherwise contemplated
              by this Agreement, and Sellers shall have received a
              certificate dated the Closing Date signed by an authorized
              officers of Purchaser to such effect.

         (b)  PERFORMANCE OF OBLIGATIONS OF OTHER PARTIES. Purchaser shall
              have satisfied all of the conditions set forth in this Section
              8.3 and performed in all material respects all obligations
              required to be performed by it under this Agreement prior to
              the Closing Date, and Seller shall have received a certificate
              signed by an authorized officer of Purchaser.


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                                                                   Page 14 of 25
<PAGE>




         (c)  EXECUTION OF RELATED AGREEMENTS. Purchaser or an Affiliate of
              Purchaser shall have executed the Proprietary Rights Agreement
              with Seller substantially in the form attached hereto as
              Exhibit A, the Transitional Manufacturing Agreement with
              Seller substantially in the form attached hereto as Exhibit B,
              and the Distribution Agreements with Seller substantially in
              the form attached hereto as Exhibit C for the mutually agreed
              upon territories.



                                   ARTICLE IX
                                   TERMINATION

9.1      TERMINATION. This Agreement may be terminated at any time prior to the
         Closing Date:

         (a)  BY MUTUAL CONSENT.  By mutual consent of Purchaser and Seller;

         (b)  BY PURCHASER OR SELLER. By either Purchaser or Seller (i) if
              the transactions contemplated by this Agreement shall not have
              been consummated on or before December 15, 1999; provided that
              the failure of the transactions to be consummated by such date
              is not caused by any breach of this Agreement or delay by the
              Party seeking such termination; or (ii) if a court of
              competent jurisdiction or other governmental or regulatory
              authority shall have issued an order, decree or ruling or
              taken any other action, in each case permanently restraining,
              enjoining or otherwise prohibiting the consummation of the
              transactions contemplated by this Agreement and such order,
              decree, ruling or other action shall have become final and not
              appealable; or (iii) if any statute, rule or regulation is
              enacted, promulgated or deemed applicable to the transactions
              contemplated by this Agreement by any competent governmental
              or regulatory authority which makes the consummation of the
              transactions illegal.

         (c)  BY PURCHASER. By Purchaser, if a material default under or a
              material breach of this Agreement by the Seller shall have
              occurred and be continuing ten (10) business days after receipt of
              notice thereof from Purchaser.

         (d)  BY SELLER. By Seller, if a material default under or a material
              breach of this Agreement by Purchaser shall have occurred and be
              continuing ten (10) business days after receipt of notice thereof
              from Seller.

         Any action taken to terminate this Agreement pursuant to this Section
         9.1 shall become effective when notice of such termination is delivered
         by the terminating party to the other party in accordance with the
         notice provision of this Agreement.

9.2      EFFECT OF TERMINATION. In the event of termination of this Agreement by
         either Purchaser or Seller in accordance with Section 9.1 above, this
         Agreement shall forthwith become void and there shall be no liability
         or obligation on the part of the terminating party or its respective
         officers, directors or employees, except that nothing set forth herein
         shall relieve a Party hereto from liability for its willful breach of
         this Agreement. Without limitation, if all of the conditions to a
         Party's obligations set forth in Article VII have been satisfied or
         waived by December 1, 1999, the failure of such Party to perform its
         obligations on or before such date shall be deemed to be a willful
         breach of this Agreement by such Party.


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                                                                   Page 15 of 25
<PAGE>


                                    ARTICLE X
                  SURVIVAL, INDEMNIFICATION AND RELATED MATTERS

10.1     SURVIVAL.

10.1.1   REPRESENTATIONS AND WARRANTIES. The representations and warranties set
         forth in Article III of this Agreement and the other Transactional
         Documents, and in any writing delivered in connection with this
         Agreement, shall survive for a period of two (2) years after the
         Closing. With respect to any breach of or inaccuracy of any
         representation or warranty set forth in Article III or in any of the
         other Transactional Documents, if a Party entitled to indemnification
         files an Indemnification Claim Notice during the applicable survival
         period specified above in this Section 10.1.1, then such representation
         and warranty shall survive beyond the applicable survival period, to
         the extent of such claim only, until such claim is resolved (whether or
         not the amount of the damages or expenses resulting from such breach
         has been finally determined at the time the notice is given) if, but
         only if (i) in the case of a claim made by a Party by reason of a third
         party claim, the written notice is accompanied by a copy of the written
         notice, if any, of the third party claimant, and (ii) in the case of
         any claim made by a Party other than by reason of a third party claim,
         either (x) some damages or expenses shall have been incurred in good
         faith at or prior to the date of such notice or (y) a reserve therefor
         would be required to be provided on a balance sheet prepared in
         accordance with GAAP.

10.1.2   COVENANTS. The covenants and agreements set forth in this Agreement and
         the other Transactional Documents, and in any writing delivered in
         connection with this Agreement, shall, unless otherwise specified
         herein or therein, survive for a period of three (3) years after the
         Closing, except as otherwise specified in Section 7.1.2. With respect
         to any breach of any covenant or agreement set forth herein or in any
         of the other Transactional Documents, if a Person entitled to
         indemnification files an Indemnification Claim Notice during the
         applicable survival period specified above in this Section 10.1.2, then
         such covenant or agreement shall survive beyond the applicable survival
         period, to the extent of such claim only, until such claim is resolved
         (whether or not the amount of the damages or expenses resulting from
         such breach has been finally determined at the time the notice is
         given) if, but only if (i) in the case of a claim made by a Party by
         reason of a third party claim, the written notice is accompanied by a
         copy of the written notice, if any, of the third party claimant and
         (ii) in the case of any claim made by a Party other than by reason of a
         third party claim, either (x) some damages or expenses shall have been
         incurred in good faith at or prior to the date of such notice or (y) a
         reserve therefor would be required to be provided on a balance sheet
         prepared in accordance with GAAP.

10.2     INDEMNIFICATION.

10.2.1   BY THE SELLER. After the Closing, and subject to the terms and
         provisions of this Agreement, the Seller will indemnify the Purchaser
         and Quidel Corporation, a California company, and hold them harmless
         against any Loss which the Purchaser and Quidel Corporation may suffer,
         sustain or become subject to as a result of:

         (a)  the failure of the Seller to perform any action or obligation of
              Seller under the Transactional Documents (subject to any
              limitations contained herein or therein);

         (b)  any liability of Purchaser for any Excluded Liabilities, including
              any and all claims, judgements, taxes, fines, penalties,
              assessments or governmental charges of any kind with respect to
              the Purchased Assets or the Business for any period prior to the
              Closing;

         (c)  any material breach of or inaccuracy of any representation,
              warranty or covenant set forth herein or in any other
              Transactional Documents (provided that the Seller is given


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                                                                   Page 16 of 25
<PAGE>


              an Indemnification Claim Notice during the applicable survival
              period specified in Section 10.1 above); or

         (d)  failure of the Seller to obtain any Governmental Approval
              necessary to be obtained in connection with the execution and
              delivery of this Agreement and the consummation of the
              transactions contemplated hereby.

10.2.2   BY THE PURCHASER. After the Closing, and subject to the terms and
         provisions of this Agreement, the Purchaser will indemnify the Seller
         and hold it harmless against any Loss which the Seller may suffer,
         sustain or become subject to as a result of:

         (a)  any failure by the Purchaser to perform any action or obligation
              of Purchaser to be performed under the Transactional Documents
              (subject to the obligations contained herein or therein);

         (b)  any material breach of or inaccuracy of any representation,
              warranty or covenant set forth herein or in any of the other
              Transactional Documents (provided that the Purchaser is given an
              Indemnification Claim Notice during the applicable survival period
              specified in Section 10.1 above);

         (c)  the failure of the Purchaser to obtain any Governmental Approval
              necessary to be obtained in connection with the execution and
              delivery of this Agreement and the consummation of the
              transactions contemplated hereby; or

         (d)  the ownership, use or operation of the Business or the Purchased
              Assets after the Closing.

10.3     LIMITATIONS ON INDEMNIFICATION. An indemnified party shall not assert
         any claim for indemnity pursuant to Section 10.2.of this Agreement with
         respect to any matter for which indemnification is available under this
         Agreement, until the aggregate amount of the Loss for which
         indemnification is available hereunder exceeds United Sates Dollars one
         hundred thousand (USD 100,000, the "Basket Amount"); PROVIDED, THAT
         thereafter the indemnifying party shall indemnify the indemnified party
         for the full amount of the Loss including the Basket Amount.
         Notwithstanding anything in this Agreement to the contrary, the maximum
         obligation of the Seller under this Article X shall not exceed fifty
         percent (50%) of the Purchase Price in the aggregate.

10.4     INDEMNIFICATION PROCEDURES.

10.4.1   NOTICE OF CLAIM. Any Party making a claim for indemnification pursuant
         to Section 10.2 above (an "Indemnified Party") must give the other
         Party from whom indemnification is sought (an "Indemnifying Party")
         written notice of such claim (an "Indemnification Claim Notice")
         promptly after the Indemnified Party receives any written notice of any
         action, lawsuit, proceeding, investigation or other claim (a
         "Proceeding") against or involving the Indemnified Party by a
         Government Authority or other third party or otherwise discovers the
         facts giving rise to such claim for indemnification. The failure to
         give such notice shall not relieve the Indemnifying Party of any of its
         obligations under this Section 10 unless, and to the extent that, such
         party is prejudiced by the failure to deliver prompt notice. Such
         notice must contain a description of the claim and the nature and
         amount of such Loss (to the extent that the nature and amount of such
         Loss is known at such time).

10.4.2   CONTROL OF DEFENSE: CONDITIONS. The obligations of an Indemnifying
         Party under this Section with respect to Losses arising from claims of
         any third party that are subject to the indemnification provided in
         Section 10.2 above shall be governed by and contingent upon the
         following additional terms and conditions:


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                                                                   Page 17 of 25
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         (a)  At its option, an Indemnifying Party may appoint as lead counsel
              of such defense any legal counsel selected by the Indemnifying
              Party (even if the provisions of Section 10.3 would or could limit
              such Indemnifying Party's obligation), which legal counsel shall
              be acceptable to the Indemnified Party (such acceptance not to be
              unreasonably withheld or delayed).

         (b)  Notwithstanding Section 10.4.2(a) above, the Indemnified Party
              will be entitled to participate in the defense of such claim and
              to employ counsel of its choice for such purpose; provided, that
              such employment shall be at the Indemnified Party's own expense
              unless (1) the employment thereof has been specifically authorized
              by the Indemnifying Party in writing or (2) the Indemnifying Party
              has failed to assume the defense and employ counsel, in which case
              the fees and expenses of the Indemnified Party's counsel shall be
              paid by the Indemnifying Party.

         (c)  The Indemnified Party will not consent to the entry of any
              judgment or enter into any settlement with respect to any
              third party claim without the prior written consent of the
              Indemnifying Party (not to be unreasonably withheld or
              delayed). The Indemnifying Party will not consent to the entry
              of any judgment or enter into any settlement with respect to
              any third party claim without the prior written consent of the
              Indemnified Party (not to be unreasonably withheld or
              delayed); provided, however, that no such consent of the
              Indemnified Party shall be required if such judgment or
              settlement contains no finding or admission of fault or guilt
              on the part of the Indemnified Party and such judgment or
              settlement contains an unconditional release of the
              Indemnified Party with respect to the particular matter.

10.5     EXCLUSIVE REMEDY, WAIVER AND RELEASE. The indemnification provided
         under this Section 10 for money damages and the equitable remedies
         described in Section 7.1.2 (non-competition), shall be the Purchaser's
         and the Seller's sole and exclusive remedies, each against the other,
         with respect to matters arising under this Agreement of any kind or
         nature, or relating to the ownership, operation, management, use or
         control of the Business and the Purchased Assets.

10.6     ACKNOWLEDGEMENT BY THE PURCHASER.

              WITHOUT LIMITING THE GENERALITY OF SECTION 10.1 OF THIS AGREEMENT,
              THE PURCHASER ACKNOWLEDGES AND AGREES THAT IT IS NOT RELYING UPON
              ANY REPRESENTATION OR WARRANTY OF THE SELLER (OTHER THAN AS SET
              FORTH HEREIN OR IN THE OTHER TRANSACTIONAL DOCUMENTS) OR ANY
              REPRESENTATION OR WARRANTY OF THE SELLER'S AFFILIATES, AGENTS OR
              ADVISORS INCLUDING, WITHOUT LIMITATION, ANY INFORMATION,
              PROJECTION OR PROMISE CONTAINED IN ANY INFORMATIONAL MEMORANDUM OR
              OTHER MATERIAL DELIVERED BY OR ON BEHALF OF THE SELLER.


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                                                                   Page 18 of 25
<PAGE>




10.7.    ARBITRATION.

10.7.1   ARBITRATION. If a dispute arises between the parties relating to the
         interpretation or performances of this Agreement or the grounds for the
         termination thereof, representatives of the parties with
         decision-making authority shall meet to attempt in good faith to
         negotiate a resolution of the dispute prior to pursuing other available
         remedies. If within thirty (30) days after such meeting the parties
         have not succeeded in negotiating a resolution of the dispute, such
         dispute shall be submitted to final and binding arbitration under the
         then current Commercial Arbitration Rules of the International Chamber
         of Commerce, by one (1) arbitrator. The place of arbitration shall be
         Geneva, Switzerland. The English language shall be used in any and all
         arbitral proceedings. The parties shall bear the costs of arbitration
         equally and shall bear their own expenses, including professional fees.
         The decision of the arbitrator shall be final and non-appealable and
         may be enforced in any court of competent jurisdiction.

10.7.2.  GOVERNING LAW. This Agreement and any dispute, including without
         limitation any arbitration, arising from the performance or breach
         hereof shall be governed by and construed and enforced in accordance
         with the laws of Germany, without reference to conflicts of laws
         principles.




                                   ARTICLE XI
                                  MISCELLANEOUS

11.1     SEVERABILITY. Should one or several provisions of this Agreement be or
         become invalid, then the Parties hereto shall substitute such invalid
         provisions by valid ones, which in their economic effect come so close
         to the invalid provisions that it can be reasonably assumed that the
         Parties would have concluded this Agreement with such new provisions.
         In case such provisions cannot be found or agreed upon, the invalidity
         of one or several provisions of this Agreement shall not affect the
         validity of the Agreement as a whole, unless the invalid provisions are
         of such essential importance for this Agreement that it is to be
         reasonably assumed that the Parties would not have concluded this
         Agreement without the invalid provisions.

11.2     NOTICES. All notices, requests, demands, waivers and other
         communication required or permitted to be given under this Agreement
         shall be given:

         If to the Seller:                           If to the Purchaser:
         Dade Behring Marburg GmbH                   Quidel Corporation
         Emil von Behring Strasse 76                 10165 McKellar Court
         35041 Marburg, Germany                      San Diego 92121
                                                     California, USA

         or, in each case, at such other address as may be specified in writing
         to the other Party.

         All such notices, requests, demands, waivers and other communications
         shall be deemed to have been received (i) if by personal delivery on
         the date after such delivery, (ii) if by certified or registered mail,
         on the seventh business day after the mailing thereof, (iii) if by
         next-day or overnight mail or delivery, on the day delivered provided
         that an additional copy is also sent by telecopy (with confirmation of
         receipt).

11.3     HEADINGS. The headings used in this Agreement are for the purpose of
         reference only and will not affect the meaning or interpretation of any
         provision of this Agreement.


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                                                                   Page 19 of 25
<PAGE>


11.4     ENTIRE AGREEMENT. This Agreement (including the Schedules hereto), and
         the other agreements and documents mentioned in and contemplated hereby
         when executed and delivered) constitute the entire agreement and
         supersede all prior agreements and understandings, both written and
         oral, between the Parties with respect to the subject matter hereof.

11.5     COUNTERPARTS. The Parties may execute this Agreement in separate
         counterparts (no one of which need contain the signatures of all
         Parties), each of which will be an original and all of which together
         will constitute one and the same instrument.

11.6     DISCLOSURE. Any information set forth in any Schedule attached to this
         Agreement or incorporated into any Section of this Agreement shall be
         considered to have been set forth in every other Schedule to this
         Agreement.

11.7     BINDING EFFECT. This Agreement shall be binding upon and inure to the
         benefit of the Parties and their respective successors and permitted
         assigns.

11.8     ASSIGNMENT. This Agreement shall not be assignable or otherwise
         transferable by any Party hereto without the prior written consent of
         the other Party hereto, except to Affiliates and to a buyer of
         substantially all the pertinent business of either Party.

11.9     NO THIRD PARTY BENEFICIARIES. Nothing in this Agreement shall confer
         any rights upon any person or entity other than the Parties and their
         respective successors and permitted assigns.

11.10    PRESS RELEASES AND PUBLIC ANNOUNCEMENTS. No Party shall issue any press
         release or make any public announcement relating to the subject matter
         of this Agreement prior to the Closing without the prior written
         approval of the other Party.

11.11    AMENDMENT, WAIVERS, ETC. Except as otherwise expressly provided herein,
         no amendment, modification or discharge of this Agreement, and no
         waiver hereunder, shall be valid or binding unless set forth in writing
         and duly executed by the Party against whom enforcement of the
         amendment, modification, discharge or waiver is sought. Any such waiver
         shall constitute a waiver only with respect to the specific matter
         described in such writing and shall in no way impair the rights of the
         Party granting such waiver in any other respect or at any other time.
         Neither the waiver by any of the Parties of a breach of or a default
         under any of the provisions of this Agreement, nor the failure by any
         of the Parties, on one or more occasions, to enforce any of the
         provisions of this Agreement or to exercise any right or privilege
         hereunder, shall be construed as a waiver of any other breach or
         default of a similar nature, or as a waiver of any of such provisions,
         rights or privileges hereunder.

11.12    NO STRICT CONSTRUCTION; INTERPRETATION. The language used in this
         Agreement will be deemed to be the language chosen by the Parties to
         express their mutual intent and no rule of strict construction will be
         applied against any Person.


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                                                                   Page 20 of 25
<PAGE>


                                   ARTICLE XII
                                 CONFIDENTIALITY

12.1     PURCHASER CONFIDENTIAL INFORMATION PROTECTION. The Purchaser hereby
         agrees that, except as set forth below, it will and shall cause its
         Affiliates to protect all Dade Behring Confidential Information from
         disclosure to third parties with the same degree of care that Purchaser
         protects its own confidential information and shall not, and shall
         cause its Affiliates not to, use any Dade Behring Confidential
         Information for any purpose other than for the purposes set forth in
         the Transactional Documents; PROVIDED, that the foregoing restrictions
         shall not apply to any Dade Behring Confidential Information: (i) which
         is or becomes available to Purchaser or its Affiliates from a source
         other than Dade Behring or its representatives provided that such
         source is not bound by a confidentiality agreement with Dade Behring;
         (ii) which is independently developed by Purchaser or its Affiliates
         without the benefit of Dade Behring Confidential Information; (iii)
         which becomes generally available to the public other than as a result
         of disclosure by the Purchaser or its Affiliates; or (iv) which is
         required to be disclosed by law, regulation or court or administrative
         order.

12.2     SELLER CONFIDENTIAL INFORMATION DEFINITION. "Dade Behring Confidential
         Information" shall mean (i) the "Schedule 1.04 Technical Information"
         (as defined in the Proprietary Rights Agreement), (ii) all non-public
         business records not relating exclusively to the Business and
         constituting part of the Purchased Assets, (iii) any proprietary or
         non-public information regarding the Seller's manufacturing procedures,
         product specifications, research and development, marketing plans or
         financial information, whether or not such information relates to the
         Business or other business of the Seller, including without limitation
         any proprietary or non-public information learned after the Closing by
         the Purchaser and/or its Affiliates through their respective
         performance under any of the Transactional Documents.

12.3     SELLER CONFIDENTIAL INFORMATION PROTECTION. The Seller hereby agrees
         that, except as set forth below, it will, and shall cause its
         Affiliates to, protect all Purchaser's Confidential Information from
         disclosure to third parties with the same degree of care that Seller
         protects its own confidential information and shall not, and shall
         cause its Affiliates not to, use any Confidential Information for any
         purpose other than the purposes set forth in the Transactional
         Documents ; provided, that the foregoing restrictions shall not apply
         to any Purchaser's Confidential Information: (i) which is or becomes
         available to Seller or its Affiliates from a source other than
         Purchaser or its representatives provided that such source is not bound
         by a confidentiality agreement with Purchaser; (ii) which is
         independently developed by Seller or its Affiliates without the benefit
         of Purchaser's Confidential Information; (iii) which becomes generally
         available to the public other than as a result of disclosure by the
         Seller or its Affiliates; or (iv) which is required to be disclosed by
         law, regulation or court or administrative order.

12.4     PURCHASER CONFIDENTIAL INFORMATION DEFINITION. "Purchaser's
         Confidential Information" shall mean (i) the "Schedule 1.02 Technical
         Information" (as defined in the Proprietary Rights Agreement), and (ii)
         any proprietary or non-public information regarding the Purchaser's
         manufacturing procedures, product specifications, research and
         development, marketing plans or financial information, of the Purchaser
         including without limitation any proprietary or non-public information
         learned after the Closing by the Seller and/or its Affiliates through
         their respective performance under any of the Transactional Documents.


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                                                                   Page 21 of 25
<PAGE>


                                  ARTICLE XIII
                                   DEFINITIONS

13.1     DEFINITION OF CERTAIN TERMS. The terms defined in this Section 13.1,
         whenever used in this Agreement (including in the Schedules), shall
         have the respective meanings indicated below for all purposes of this
         Agreement:

         "AFFILIATE" of a Person shall mean a Person that directly or indirectly
         through one or more intermediaries, controls, is controlled by, or is
         under common control with, the first Person.

         "CONTROL" (including the terms "CONTROLLED BY" and "UNDER COMMON
         CONTROL WITH") shall mean the possession, directly or indirectly, of
         the power to direct or cause the direction of the management policies
         of a person, whether through the ownership of voting securities, by
         contract or credit arrangement, as trustee or executor, or otherwise.

         "AGREEMENT" shall mean this Asset Purchase Agreement, including the
         Schedules hereto.

         "APPLICABLE LAW" shall mean all applicable provisions of all (i)
         constitutions, treaties, statutes, laws (including the common law),
         rules, regulations, ordinances, codes or orders of any Governmental
         Authority and (ii) Governmental Approvals.

         "BUSINESS" shall mean the Rapignost -Registered Trademark- Urine Test
         Strip Business relating to the human in vitro diagnosis of diseases or
         the determination of health status, i.e., the exclusion of diseases.

         "CONSENT" shall mean any consent, approval, authorization, waiver,
         permit, grant, franchise, concession, agreement, license, exemption or
         order of registration, certificate, declaration or filing with, or
         report or notice to, any Person, including but not limited to any
         Governmental Authority, in each case only if the failure to obtain,
         file, report or give notice would have a Material Adverse Effect.

         "GAAP" shall mean the generally accepted accounting principles of the
         United States.

         "DISTRIBUTION AGREEMENTS" shall mean the Distribution Agreements for
         the mutually agreed upon territories, substantially in the form
         attached hereto as Exhibit C.

         "GOVERNMENTAL APPROVAL" shall mean any Consent of any Governmental
         Authority.

         "GOVERNMENTAL AUTHORITY" shall mean any nation or government, any state
         or other political subdivision thereof.

         "KNOWN" or "KNOWLEDGE" shall mean the actual personal knowledge,
         without imputation of any other person and without independent
         investigation, of any senior manager employed by a Party for whom a
         significant portion of his or her duties relates to matters as to which
         the applicable representation or warranty is made hereunder.

         "LEASE AGREEMENT" shall mean the Lease Agreement with for that certain
         manufacturing facility located in Marburg, Germany relating to the
         Business, substantially in the form attached hereto as Exhibit D.

         "LIEN" shall mean any mortgage, pledge, charge, hypothecation or
         security interest.

         "LOSS" shall mean any loss, liability, deficiency, action, suit,
         proceeding, damage or expense, (including reasonable attorneys fees)
         but excluding any consequential damages.


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                                                                   Page 22 of 25
<PAGE>


         "MATERIAL ADVERSE EFFECT" shall mean a material adverse effect on the
         financial condition or operating results of the Business (taken as a
         whole).

         "PERSON" shall mean an individual, a partnership, a corporation, an
         association, a limited liability company, a joint stock company, a
         trust, a joint venture, an unincorporated organization or a
         Governmental Authority.

         "PROPRIETARY RIGHTS" shall be as defined in the Proprietary Rights
         Agreement.

         "PROPRIETARY RIGHTS AGREEMENT" shall mean the Proprietary Rights
         Agreement, substantially in the form attached hereto as Exhibit A.

         "REASONABLE EFFORTS" shall mean reasonable efforts which are
         commercially reasonable under the circumstances, excluding the payment
         of any money or other consideration to any third party or the
         commencement of any litigation or arbitration.

         "TAX" or "TAXES" shall mean any federal, state, local or foreign
         income, gross receipts, license, payroll, employment, excise,
         severance, stamp, occupation, premium, property, windfall, profits,
         environmental, customs, capital stock, franchise, employees' income
         withholding, foreign or domestic withholding, social security,
         unemployment, disability, real property, personal property, sales, use,
         transfer, value added, alternative or add-on minimum or other similar
         tax, governmental fee, governmental assessment or governmental charge
         of any kind whatsoever, including any interest, penalties or additions
         to Tax or additional amounts with respect to the foregoing.

         "TAX RETURN" shall mean any return, report, declaration, form, claim
         for refund or information return or statement relating to Taxes,
         including any schedule or attachment thereto, and including any
         amendment thereof.

         "TRANSACTIONAL DOCUMENTS" shall mean this Agreement, the Proprietary
         Rights Agreement, the Transitional Manufacturing Agreement, the
         Distribution Agreements, and the Lease Agreement.

         "TRANSITIONAL MANUFACTURING AGREEMENT" shall mean the Transitional
         Manufacturing and Transfer Assistance Agreement, substantially in the
         form attached hereto as Exhibit B.



13.2     CROSS-REFERENCES TO OTHER DEFINED TERMS.

         "ASSUMED LIABILITIES" shall have the meaning set forth in Section 1.3.

         "AVERAGE INVENTORY" shall have the meaning set forth in Section 2.4.1.

         "BASKET AMOUNT" shall have the meaning set forth in Section 10.3.

         "CONTRACTS" shall have the meaning set forth in Section 1.1.3.

         "EXCLUDED ASSETS" shall have the meaning set forth in Section 1.2.

         "EXCLUDED LIABILITIES" shall have the meaning set forth in Section 1.4.

         "INDEMNIFICATION CLAIM NOTICE" shall have the meaning set forth in
         Section 10.4.1.

         "INDEMNIFIED PARTY" shall have the meaning set forth in Section 10.4.1.

         "INDEMNIFYING PARTY" shall have the meaning set forth in Section
         10.4.1.

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                                                                   Page 23 of 25

<PAGE>


         "INVENTORY" shall have the meaning set forth in Section 1.1.2.

         "PROCEEDING" shall have the meaning set forth in Section 10.4.1.

         "PURCHASED ASSETS" shall have the meaning set forth in Section 1.1.

         "PURCHASE PRICE" shall have the meaning set forth in Section 2.1.

         "TRANSACTION EXPENSES" shall have the meaning set forth in Section
         7.3.1.

13.3     OTHER DEFINITIONAL PROVISIONS.

13.3.1   ACCOUNTING TERMS. Accounting terms (if any) which are not otherwise
         defined in this Agreement have the meanings given to them under GAAP.
         To the extent that the definition of such accounting term that is
         defined in this Agreement is inconsistent with the meaning of such term
         under GAAP, the GAAP definition will control.

13.3.2   "HEREOF," ETC. The terms "hereof," "herein" and "hereunder" and terms
         of similar import are references to this Agreement as a whole and not
         to any particular provision of this Agreement. The term "including" as
         used in this Agreement is used to list items by way of example and
         shall not be deemed to constitute a limitation of any term or provision
         contained herein. As used in this Agreement, the singular or plural
         number shall be deemed to include the other whenever the context so
         requires. Section, clause and Schedule references contained in this
         Agreement are references to Sections, clauses and Schedules in or to
         this Agreement, unless otherwise specified.


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                                                                   Page 24 of 25
<PAGE>


                                  * * * * * *



IN WITNESS WHEREOF, the Parties have duly executed this Asset Purchase Agreement
as of the date first above written.



DADE BEHRING MARBURG GMBH



/s/ DONAL QUINN
- ---------------------------------------------
Name:    Donal Quinn
Title:   President, Europe Middle East Africa
         Managing Director




QUIDEL CORPORATION



/s/ ANDRE DE BRUIN
- ---------------------------------------------
Name:    Andre de Bruin
Title:   President, Chief Executive Officer




QUIDEL DEUTSCHLAND GMBH



/s/ ANDRE DE BRUIN
- ---------------------------------------------
Name:    Andre de Bruin
Title:



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                                                                   Page 25 of 25


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