PANORAMA SERIES FUND INC
497, 2000-03-13
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                           PANORAMA SERIES FUND, INC.
                                Growth Portfolio

                      Supplement dated March 8, 2000 to the
                         Prospectus dated April 30, 1999


      The paragraph  captioned  "Portfolio  Managers" under the section "How the
Portfolio is Managed" on page 7 is deleted and replaced with the following:

           The  portfolio  managers  of the  Portfolio  are  Charles  Albers and
      Nikolaos Monoyios,  who are also Vice Presidents of the Company.  They are
      the persons  primarily  responsible  for the day-to-day  management of the
      Portfolio's  investments.  Mr.  Albers is a Senior Vice  President  of the
      Manager and Mr.  Monoyios is a Vice  President  of the  Manager.  Prior to
      joining  the  Manager  in April  1998,  they were  portfolio  managers  at
      Guardian  Investor  Services  (from  1972  and  1979,  respectively),  the
      investment management subsidiary of The Guardian Life Insurance Company.



March 8, 2000                                            608PS.001

<PAGE>

                           PANORAMA SERIES FUND, INC.
                             Total Return Portfolio

                      Supplement dated March 1, 2000 to the
                         Prospectus dated April 30, 1999


      The paragraph  captioned  "Portfolio  Managers" under the section "How the
Portfolio is Managed" on page 8 is deleted and replaced with the following:

           The portfolio  managers of the Portfolio  are Patrick  Bisbey,  David
      Dalzell and Stephen Libera. They are the persons primarily responsible for
      the day-to-day management of the Portfolio's  investments.  Messrs. Bisbey
      and Dalzell became portfolio managers on March 1, 2000, and Mr. Libera has
      been a portfolio  manager of the  Portfolio  since 1982.  Mr.  Bisbey is a
      Managing  Director and Manager of Trading and Portfolio  Operations (since
      June, 1992) of Trinity Investment Management  Corporation  ("Trinity"),  a
      wholly-owned  subsidiary of the Manager's  immediate  parent,  Oppenheimer
      Acquisition  Corp.  Mr.  Dalzell is a  research  analyst  and trader  with
      Trinity  (since  November,  1985),  prior  to  which  he  was a  financial
      consultant  with Merrill  Lynch Pierce Fenner & Smith  Incorporated  and a
      trader  for  First  Chicago  Trading  Consultants.  Mr.  Libera  is a Vice
      President of the Manager.  Before  joining the Manager in 1996, Mr. Libera
      was employed as a portfolio  manager by Connecticut  Mutual Life Insurance
      Company. Each is a Vice President of the Company.



March 1, 2000                                            609PS.001

<PAGE>

                           PANORAMA SERIES FUND, INC.
                      Supplement dated March 8, 2000 to the
              Statement of Additional Information dated April 30, 1999,
                             Revised January 1, 2000

      1. The following is added to the section captioned "Directors and Officers
of the Company" on page 37:

      Patrick  Bisbey,  Vice  President and  Portfolio  Manager of Total Return
      Portfolio, Age: 41
      301 North Spring Street, Bellefonte, PA  16823
      Managing  Director and Manager of Trading and Portfolio  Operations (since
      June, 1992) of Trinity Investment Management  Corporation  ("Trinity"),  a
      wholly-owned  subsidiary  of  OppenheimerFunds,  Inc's  immediate  parent,
      Oppenheimer Acquisition Corp.

      David  Dalzell,  Vice  President  and  Portfolio  Manager of Total  Return
      Portfolio, Age: 33 301 North Spring Street,  Bellefonte, PA 16823 Research
      analyst and trader with Trinity (since November,  1995), prior to which he
      was a  financial  consultant  with  Merrill  Lynch  Pierce  Fenner & Smith
      Incorporated and a trader for First Chicago Trading Consultants.

      Charles Albers,  Vice President and Portfolio Manager of Growth Portfolio,
      Age: 59 Two World Trade Center,  New York, New York 10048-0203 Senior Vice
      President  of  the  Manager  (since  April  1998);  an  officer  of  other
      Oppenheimer  funds;  a  Certified  Financial  Analyst;   formerly  a  Vice
      President  and  portfolio  manager for  Guardian  Investor  Services,  the
      investment  management  subsidiary of The Guardian Life Insurance  Company
      (since 1972).

      Nikolaos D.  Monoyios,  Vice  President  and  Portfolio  Manager of Growth
      Portfolio,  Age: 60 Two World Trade Center,  New York, New York 10048-0203
      Vice  President of the Manager  (since  April  1998);  an officer of other
      Oppenheimer  funds;  a  Certified  Financial  Analyst;   formerly  a  Vice
      President  and  portfolio  manager for  Guardian  Investor  Services,  the
      investment  management  subsidiary of The Guardian Life Insurance  Company
      (since 1979).

2.      The first  sentence of the  biography  for Peter M. Antos in the section
        captioned  "Directors and Officers of the Company" on page 37 is revised
        to read as follows:

           Peter M. Antos, Vice President and Portfolio Manager of the
           Value/Growth and Growth/Income stock components of the LifeSpan
           Portfolios; Age: 52 . . . .

3.      The first sentence of the biography for Stephen F. Libera in the section
        captioned  "Directors and Officers of the Company" on page 37 is revised
        to read as follows:

           Stephen F. Libera, Vice President and Portfolio Manager of the
           Total Return Portfolio and the Short-Term Bonds and
           Government/Corporate Bonds component of the LifeSpan Portfolios;
           Age: 47 . . . .

4.      The first  sentence of the  biography  for Michael C.  Strathearn in the
        section captioned  "Directors and Officers of the Company" on page 37 is
        revised to read as follows:

           Michael C. Strathearn, Vice President and Portfolio Manager of the
           Value/Growth and Growth/Income stock components of the LifeSpan
           Portfolios; Age: 45 . . . .

5.      The first  sentence of the biography for Kenneth B. White in the section
        captioned  "Directors and Officers of the Company" on page 37 is revised
        to read as follows:

           Kenneth B. White, Vice President and Portfolio Manager of the
           Value/Growth and Growth/Income stock components of the LifeSpan
           Portfolios; Age: 46 . . . .

6.      The biography for Arthur J. Zimmer in the section  captioned  "Directors
        and Officers of the Company" on page 37 is deleted in its entirety.


      March 8, 2000                                      PANPX.009



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