PANORAMA SERIES FUND INC
497, 2001-01-09
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                           PANORAMA SERIES FUND, INC.
                             Total Return Portfolio

                    Supplement dated January 2, 2001 to the
                          Prospectus dated May 1, 2000


      The paragraph  captioned  "Portfolio  Managers" under the section "How the
Portfolio is Managed" on page 8 is deleted and replaced with the following:

           The portfolio  managers of the Portfolio are Patrick  Bisbey and John
      Kowalik.  They are the persons  primarily  responsible  for the day-to-day
      management of the Portfolio's  investments.  Mr. Bisbey became a portfolio
      manager on March 1, 2000, and Mr.  Kowalik  became a portfolio  manager on
      June 26, 2000.  Mr.  Bisbey is a Managing  Director and Manager of Trading
      and  Portfolio   Operations  (since  June,  1992)  of  Trinity  Investment
      Management  Corporation  ("Trinity"),  a  wholly-owned  subsidiary  of the
      Manager's immediate parent, Oppenheimer Acquisition Corp. Mr. Kowalik is a
      Senior Vice President of the Manager. Prior to joining the Manager in July
      1998, he was Managing Director and senior portfolio manager for Prudential
      Investments  Global Fixed Income  Group.  Each is a Vice  President of the
      Company.



January 2, 2001                                     609PS.001

<PAGE>

                           PANORAMA SERIES FUND, INC.
                             Total Return Portfolio

                    Supplement dated January 2, 2001 to the
             Statement of Additional Information dated May 1, 2000


1.           The biography for David Dalzell in the section captioned "Directors
             and Officers of the Company" on page 40 is deleted in its entirety.




January 2, 2001                                609PX.001




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