GENOME THERAPEUTICS CORP
S-3/A, 1996-02-13
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
Previous: GENOME THERAPEUTICS CORP, 10-Q/A, 1996-02-13
Next: FIRST BANKING CO OF SOUTHEAST GEORGIA, SC 13G/A, 1996-02-13



<PAGE>   1
 
   
   AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON FEBRUARY 13, 1996
    
   
                                                      REGISTRATION NO. 333-00127
    
================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                            ------------------------
   
                                AMENDMENT NO. 4
    
                                       TO
 
                                    FORM S-3
            REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                            ------------------------
 
                           GENOME THERAPEUTICS CORP.
             (Exact name of Registrant as specified in its charter)
<TABLE>
         <S>                                                     <C>
                   MASSACHUSETTS                                       04-2297484
           (State or other jurisdiction                             (I.R.S. Employer
         of incorporation or organization)                       Identification Number)
</TABLE>
                            ------------------------
 
                100 BEAVER STREET, WALTHAM, MASSACHUSETTS 02154
                                 (617) 893-5007
  (Address, including zip code, and telephone number, including area code, of
                   Registrant's principal executive offices)

                            ------------------------
 
                                 FENEL M. ELOI
 
             VICE PRESIDENT, TREASURER, AND CHIEF FINANCIAL OFFICER
                           GENOME THERAPEUTICS CORP.
                               100 Beaver Street
                          Waltham, Massachusetts 02154
                                 (617) 893-5007
 (Name, address, including zip code, and telephone number, including area code,
                             of agent for service)
                            ------------------------
 
                                   COPIES TO:
<TABLE>
            <S>                                               <C>
               DAVID C. CHAPIN, ESQ.                             DAVID E. REDLICK, ESQ.
                   ROPES & GRAY                                       HALE AND DORR
              One International Place                                60 State Street
            Boston, Massachusetts 02110                        Boston, Massachusetts 02109
</TABLE>
 
                            ------------------------
 
        Approximate date of commencement of proposed sale to the public:
   As soon as practicable after the Registration Statement becomes effective.

                            ------------------------
 
     If the only securities being registered on this Form are being offered
pursuant to dividend or interest reinvestment plans,
please check the following box. / /
 
     If any of the securities being registered on this Form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. / /
 
     If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective registration statement for the same offering. / /
 
     If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. / /
 
     If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. / /

                            ------------------------
 
     THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR
DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL
FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION
STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(A) OF
THE SECURITIES ACT OF 1933 OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME
EFFECTIVE ON SUCH DATE AS THE COMMISSION, ACTING PURSUANT TO SAID SECTION 8(A),
MAY DETERMINE.

================================================================================
<PAGE>   2
 
                                    PART II
 
                     INFORMATION NOT REQUIRED IN PROSPECTUS
 
   
ITEM 16.  EXHIBITS
    
 
     The following is a list of exhibits filed as a part of this registration
statement.
 
<TABLE>
     (A) EXHIBITS
 
<CAPTION>
   
  EXHIBIT
   NUMBER                                       DESCRIPTION
- ------------                                    -----------
      <S>     <C>
    1     --  Underwriting Agreement. (10)
    3.1   --  Restated Articles of Organization. (1)
    3.1.1 --  Amendment dated January 5, 1982 to Restated Articles of Organization. (2)
    3.1.2 --  Amendment dated January 24, 1983 to Restated Articles of Organization. (3)
    3.1.3 --  Amendment dated January 17, 1984 to Restated Articles of Organization. (4)
    3.1.4 --  Amendment dated December 9, 1987 to Restated Articles of Organization. (5)
    3.1.5 --  Amendment dated January 24, 1994 to Restated Articles of Organization. (6)
    3.1.6 --  Amendment dated August 31, 1994 to Restated Articles of Organization. (6)
    3.2   --  By-Laws of the Company. (1)
    3.2.1 --  Amendment dated October 20, 1987 to the By-laws. (7)
    3.2.2 --  Amendment dated October 16, 1989 to the By-laws. (8)
    4.1   --  Specimen Certificate for shares of Common Stock, $.10 par value of the Company.
              (9)
    4.2   --  Warrant to Purchase Shares of Common Stock. (11)
    5     --  Opinion of Ropes & Gray.
    23.1  --  Consent of Ropes & Gray (contained in its opinion filed as Exhibit 5 hereto).
    23.2  --  Consent of Arthur Andersen LLP.
    23.3  --  Consent of Lahive & Cockfield. (11)
    24    --  Power of Attorney. (9)
    
 
- ---------------
<FN> 
 (1) Filed as an exhibit to the Company's Registration Statement on Form S-1
     (No. 2-75230) and incorporated herein by reference.
 
 (2) Filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the
     quarter ended February 27, 1982 and incorporated herein by reference.
 
 (3) Filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the
     quarter ended February 26, 1983 and incorporated herein by reference.
 
 (4) Filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the
     quarter ended February 25, 1984 and incorporated herein by reference.
 
 (5) Filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the
     quarter ended November 28, 1987 and incorporated herein by reference.
 
 (6) Filed as an Exhibit to the Company's Annual Report on Form 10-K for the
     fiscal year ended August 31, 1994 and incorporated herein by reference.
 
 (7) Filed as an exhibit to the Company's Annual Report on Form 10-K for the
     fiscal year ended August 31, 1987 and incorporated herein by reference.
 
 (8) Filed as an exhibit to the Company's Annual Report on Form 10-K for the
     fiscal year ended August 31, 1989 and incorporated herein by reference.
 
 (9) Previously filed with the Commission on January 10, 1996.
 
(10) Previously filed with the Commission on January 19, 1996.
 
   
(11) Previously filed with the Commission on February 12, 1996.
    
</TABLE>
 
     (B) FINANCIAL STATEMENT SCHEDULES
 
     Schedule II -- Valuation and Qualifying Accounts
 
   
     All other schedules are not submitted because either they are not
applicable, not required or because the information is contained in the
    
financial statements, including the Notes thereto.
 
                                      II-1
<PAGE>   3
 
                                   SIGNATURES
 
   
     Pursuant to the requirements of the Securities Act of 1933, the registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-3 and has duly caused this Amendment No. 4 to
the Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Waltham, Commonwealth of
Massachusetts, on this 13th day of February, 1996.
    
                                            GENOME THERAPEUTICS CORP.
 
                                                     /S/ FENEL M. ELOI
                                            By: ................................
                                                       FENEL M. ELOI
                                                 Vice President, Treasurer
                                                and Chief Financial Officer
 
<TABLE>
   
     Pursuant to the requirements of the Securities Act of 1933, this Amendment
No. 4 to the Registration Statement has been signed below by the following
persons in the capacities and on the dates indicated.
    
 
   
<CAPTION>
             SIGNATURE                               TITLE                         DATE
             ---------                               -----                         ----
<C>                                   <S>                                    <C>
     /S/ ROBERT J. HENNESSEY*         Chairman of the Board of Directors,    February 13, 1996
 .................................    President and Chief Executive
        ROBERT J. HENNESSEY           Officer (Principal Executive
                                      Officer)

         /S/ FENEL M. ELOI            Vice President, Treasurer and Chief    February 13, 1996
 .................................    Financial Officer (Principal
           FENEL M. ELOI              Financial and Accounting Officer)

      /S/ ORRIE M. FRIEDMAN*          Director                               February 13, 1996
 .................................
         ORRIE M. FRIEDMAN

       /S/ PHILIP J. LEDER*           Director                               February 13, 1996
 .................................
          PHILIP J. LEDER

        /S/ LAWRENCE LEVY*            Director                               February 13, 1996
 .................................
           LAWRENCE LEVY

      /S/ DONALD J. MCCARREN*         Director                               February 13, 1996
 .................................
        DONALD J. MCCARREN

      /S/ STEVEN M. RAUSCHER*         Director                               February 13, 1996
 .................................
        STEVEN M. RAUSCHER
</TABLE>
    
 
      /S/ FENEL M. ELOI
*By: .........................
        FENEL M. ELOI
       Attorney-in-Fact
 
                                      II-2

<PAGE>   1

                                                                     EXHIBIT 5

                                                             February 13, 1996


Genome Therapeutics Corp.
100 Beaver Street
Waltham, Massachusetts 02154

  Re:  Registration Statement on
       Form S-3 (No. 333-00127)
       -------------------------

Ladies and Gentlemen:

     This opinion is rendered to you in connection with the above-mentioned 
registration statement (the "Registration Statement") on Form S-3 filed with 
the Securities and Exchange Commission under the Securities Act of 1933, as 
amended (the "Act"), for the registration under the Act by Genome Therapeutics 
Corp. (the "Company") of up to 2,875,000 shares of the Company's Common Stock, 
$0.10 par value per share (the "Shares").

     The Shares are to be sold pursuant to an underwriting agreement (the 
"Underwriting Agreement") to be entered into between the Company and the 
underwriter named herein (the "Underwriter").

     We have acted as counsel to the Company in connection with the issuance 
and sale of the Shares and the preparation of the Registration Statement. For 
purposes of this opinion, we have examined and relied upon such documents and 
records as we have deemed necessary.

     We have assumed that the Underwriting Agreement will have been duly 
executed and delivered, all in accordance with the authorizing resolutions of 
the Board of Directors of the Company, and that the Shares will be sold and 
transferred only upon payment therefor and as provided in the Underwriting 
Agreement.

     Based upon the foregoing, we are of the opinion that the Shares have been 
duly authorized and when issued, delivered, and paid for as provided in the 
Underwriting Agreement will be validly issued, fully-paid and nonassessable.

     We hereby consent to the filing of this opinion as part of the 
Registration Statement and to the use of our name therein and in the related 
prospectus under the caption "Legal Matters."

     It is understood that this opinion is to be used only in connection with 
the offer and sale of the Shares while the Registration Statement is in effect.

                                            Very truly yours,


                                            /s/  ROPES & GRAY
                                            --------------------------------
                                            Ropes & Gray    

<PAGE>   1
 
                                                                    EXHIBIT 23.2
 
                   CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS
 
     As independent public accountants, we hereby consent to the use of reports
(and to all references to our Firm) included in or made part of this
Registration Statement.
 
                                            ARTHUR ANDERSEN LLP
 
February 9, 1996


© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission