OPPENHEIMER SERIES FUND INC
497, 1998-02-24
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                                                   (logo)
                                              OPPENHEIMERFUNDS
Denis Molleur                                 OppenheimerFunds, Inc.
Vice President                                Two World Trade Center, 34th Floor
and Associate Counsel                         New York, NY 10048-0203
                                              Tel 212 323 0200




                                             February 24, 1998



Securities and Exchange Commission
Mail Stop 0-7, Filer Support
6432 General Green Way
Alexandria, VA 22312

          RE:  Oppenheimer Series Fund, Inc.  ("Registrant")
               Reg No. 2-75276
               File No.  811-3346

To the Securities and Exchange Commission:

        An electronic  filing is hereby made on behalf of  Oppenheimer  LifeSpan
Growth Fund,  Oppenheimer LifeSpan Balanced Fund and Oppenheimer LifeSpan Income
Fund, each a series of the Registrant ("LifeSpan Funds") pursuant to Rule 497(e)
of the  Securities  Act of 1933, as amended.  Such filing  includes a supplement
dated  February 24, 1998 to the  Prospectus of the LifeSpan Funds dated February
19, 1998.

        If there are any questions, please contact the undersigned.

                                            Sincerely,


                                            /s/ Denis Molluer
                                            ----------------------------
                                            Denis Molleur
                                            Vice President
                                            and Assistant  Counsel
                                            (212) 323-0560

cc:     Gordon Altman Butowsky Weitzen Shalov & Wein
        KPMG Peat Marwick  LLP
        Gloria LaFond
        Grace Loffredo


<PAGE>


                        OPPENHEIMER LIFESPAN GROWTH FUND
                       OPPENHEIMER LIFESPAN BALANCED FUND
                        OPPENHEIMER LIFESPAN INCOME FUND

                    Supplement dated February 24, 1998 to the
                       Prospectus dated Februrary 19, 1998

The Prospectus is changed as follows:

The  following  is added as the first  paragraph  under the heading  "How To Buy
Shares -- How Much Must You Invest?" on page 51:

      Shares of the Funds are not available for sale to new investors, including
      shares  purchased  by  exchange  from other  Oppenheimer  funds,  lump-sum
      purchases,  and purchases  under an Asset Builder Plan  (described on page
      53)  or  by  reinvestment  of  dividends  or   distributions   from  other
      Oppenheimer  funds, or under the  "Reinvestment  Privilege"  (described on
      page 65). Existing Fund  shareholders may purchase  additional Fund shares
      through  subsequent  investments or reinvestment of a Fund's  dividends or
      distributions,  until  such  time as the  reorganization  of (i)  LifeSpan
      Growth  Fund  with and  into  Oppenheimer  Disciplined  Value  Fund,  (ii)
      LifeSpan  Balanced Fund with and into Oppenheimer  Disciplined  Allocation
      Fund, and (iii) LifeSpan Income Fund with and into  Oppenheimer  Bond Fund
      may  close.  The  foregoing  is  subject to the right of each Fund and the
      Distributor,  in their  complete  discretion,  to modify or terminate  the
      terms of this  offer at any  time  without  prior  notice.  The  remaining
      sections of this  Prospectus are hereby amended to conform to the terms of
      this offer.





February  24, 1998                                                   PS0305.010




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