November 1, 2000
State Street Bank and Trust Company
225 Franklin Street
Boston, MA 02110
Re: JOHN HANCOCK SERIES TRUST
John Hancock Focused Relative Value Fund
Dear Sirs:
John Hancock Series Trust (the "Trust"), a Massachusetts business
trust, on its own behalf and on behalf of the above-named series of the Trust
(the "Fund") hereby notifies State Street Bank and Trust Company (the "Bank")
that the Trust desires to place and maintain the Fund's securities and cash in
the custody of the Bank pursuant to the Amended and Restated Master Custodian
Agreement between John Hancock Mutual Funds and the Bank dated March 9, 1999 to
be effective November 1, 2000.
If the Bank agrees to provide such services, please sign below and
return a signed original of this letter to the undersigned.
STATE STREET BANK JOHN HANCOCK SERIES TRUST
AND TRUST COMPANY On behalf of John Hancock Focused
Relative Value Fund
By: /s/ Ronald E. Logue By: /s/Maureen R. Ford
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Name: Ronald E. Logue Name: Maureen R. Ford
Title:Vice President Title: President
Attest: /s/Nelson H. Graves Attest: /s/ Wendi Vincent
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s:\funds\series\focusedrelativevalue\Custodian Agt Amendment