PUTNAM HEALTH SCIENCES TRUST
N-30D, 1994-04-26
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(logo)

Putnam
Health
Sciences
Trust

Semiannual
Report
February 28, 1994

(artwork)

For investors seeking 
capital appreciation 
through investments in
the health sciences
industries

     Contents
 2   How your fund performed
 3   From the Chairman
 4   Report from Putnam Management
     Semiannual Report
 6   Portfolio of investments owned
 9   Financial statements
18   Fund performance supplement
19   Your Trustees

A member
of the Putnam
Family of Funds
<PAGE>
How your
fund performed

For periods ended February 28, 1994
Total return*                   Fund+
            Class A              Class B            S&P 500(R)  Consumer
      NAV         POP     NAV    CDSC Index        Price Index
6 months       10.45%   4.09%  10.06% 5.06%  2.12%       1.31%
1 year          12.76    6.27   11.25  6.25   8.28        2.51
5 years        109.11   97.11      --    --  89.52       20.65
  annualized    15.90   14.54      --    --  13.64        3.83
10 years       341.39  316.06      --    -- 320.47       43.27
  annualized    16.01   15.32      --    --  15.44        3.66

Share data                                 Class A               Class B
                          NAV           POP    NAV
August 31, 1993                $24.40       $25.89      $24.28
February 28, 1994              $26.65       $28.28      $26.48

Distributions                                        Long-term
6 months ended                   Investment            capital
February 28, 1994      Number  income        gains       Total
Class A             1  $0.240        $0.051 $0.291
Class B             1  $0.185        $0.051 $0.236

Total return at end of most recent calendar quarter
Periods ended March 31, 1993
                      Class A              Class B
                  NAV     POP           NAV    POP
6 months        2.81%  -3.11%         2.40% -2.60%
1 year           4.00   -1.98          3.08  -1.92
5 years         87.32   76.56            --     --
  annualized            13.37   12.04           --          --
10 years       313.01  289.33            --     --
  annualized            15.24   14.56           --          --
Life of class              --      --         4.15        0.15
  annualized               --      --         3.84        0.14

*Performance data represent past results. Investment return and
net asset value will fluctuate so that an investor's shares, when
redeemed, may be worth more or less than their original cost. 

+The fund began investment operations on May 28, 1982, offering
shares now known as class A shares. Effective March 1, 1993, the
fund began offering class B shares. Results for each share class
will differ.
<PAGE>
Terms you need to know

Total return is the change in value of an investment from the
beginning to the end of a period, assuming the reinvestment of
all distributions. It may be shown at net asset value or at
public offering price.

Net asset value (NAV) is the value of all your fund's assets,
minus any liabilities, divided by the number of outstanding
shares, not reflecting any sales charge. 

Public offering price (POP) is the price of a mutual fund share
plus the maximum sales charge levied at the time of purchase. 

Contingent deferred sales charge (CDSC) is a charge applied at
the time of the redemption of shares rather than the time of
purchase. It generally declines and eventually disappears over a
stated period. 

Class A shares are the shares of your fund offered subject to an
initial sales charge. Your fund's POP includes the maximum 5.75%
sales charge. 

Class B shares are the shares of your fund offered with no
initial sales charge. Within the first six years of purchase,
they are subject to a CDSC declining from 5% to 1%. After the
sixth year, the CDSC no longer applies.

Please see the fund performance supplement on page 18 for
additional information about performance comparisons.
<PAGE>
From the
Chairman

(photograph of George Putnam)

George Putnam
Chairman
of the Trustees

(C) Karsh, Ottawa

Dear Shareholder:

It is safe to predict that virtually every American will be
affected by the outcome of the debate now taking place over the
nation's health care delivery system. Although the discussion has
been proceeding in earnest for well over a year, it is still too
early to predict the final shape of these changes.

Putnam Management and Joanne Soja, portfolio manager of Putnam
Health Sciences Trust, are not waiting for the drama to play
itself out. They have identified several areas of the health care
industry they believe have the opportunity to gain, regardless of
what reforms finally emerge.

In the closing quarter of 1993, Joanne became more optimistic
about prospects for health care stocks as valuations of these
stocks became extremely low in relation to valuations of the
market overall. As she tells you in the Report from Putnam
Management that follows, Joanne believes the market's concern
over health care reform has resulted in some extraordinarily
attractive prices for the stocks of many companies. She is
studying these companies carefully, seeking the ones most likely
to benefit from the coming changes.

We are confident that she will continue to find them. Likewise,
we remain firm in our belief that patient investors will be well
rewarded over the long term by a diversified and closely
monitored investment in the health care industry.

Respectfully yours,
(signature of George Putnam)
George Putnam
April 20, 1994
<PAGE>
Report from
Putnam Management

Putnam Health Sciences Trust's results during the six months
ended February 28, 1994, clearly support our judgment that the
two-year underperformance of health care stocks relative to the
market may be near an end. At the same time, we expect a good
deal of volatility in the prices of health care stocks as the
industry continues to work through a significant number of
challenges. 

It is in this context that we report the fund's 10.45% total
return for class A shares at net asset value for the period,
compared with the 2.12% average return for stocks measured by the
Standard & Poor's 500 Index.

The shape of reform Much of the volatility we expect in health
care stocks will trace back to the ongoing national debate on
health care and the industry's response to this debate. In the
final analysis, the threat of legislation may play a more
significant role than the legislation itself in achieving reform.
For example, the prospect of price controls early in the debate
has already pressured companies to trim the rate of escalation in
health care costs. It has forced them to tighten their belts,
rethink their market focus, and service their customers more
aggressively. 

While it is never safe to bet on what Washington will do, it is
already clear that the plan as submitted by President Clinton
will not survive intact. In our judgment, what is likely to
emerge is a less bureaucratic and rigid version. We believe this
ultimately means a greater role for market forces in bringing
down the cost of health care. To that end, we have been seeking
out companies that can best prosper in such an environment --
companies that can deliver the most cost-effective care. 

Industry's response We are increasingly seeing restructuring,
consolidation, and creative alliances as one of the health care
industry's responses to reform. For example, portfolio company
Columbia Hospitals' recent merger with two large public hospital
companies, Galen and Hospital Corporation of America, has created
an entity large enough to negotiate significant cost savings with
suppliers and distributors in return for shifting its business to
them. As Columbia lowers its own operating costs, it can position
itself as a low-cost provider of services. 

The purchase of Medco Containment Services by portfolio company
Merck & Co. represents this drug manufacturer's attempt to
deliver lower costs or better value to a client base increasingly
seeking managed care alternatives to drug cost inflation.
<PAGE>
Owens & Minor, another portfolio company, is taking on more of
the inventory costs for its hospital customers, thus allowing the
hospitals more productive use of their cash. We believe the
company's recent move to merge with Stuart Medical would provide
consolidation of its distribution capacity, more efficiencies,
and clout in seeking large national accounts. 

Outlook The market is looking more closely at the potential of
individual companies, rather than lumping all health care stocks
together. While we can never guarantee future results, we believe
the companies in your fund's portfolio are among those likely to
benefit most from this change in the market's focus. 

Here is how we view prospects for major sectors of the health
care market.

Biotechnology Because of a number of disappointments in this
area, investors are taking a harder look at clinical data before
buying. The Food and Drug Administration recently approved
exciting new products at Genentech, another portfolio company,
and Chiron, partially restoring the market's confidence in the
potential of biotechnology to develop new therapies for
previously unserved markets.

Medical supplies and technology Many companies in this sector
were forced to bring down their cost structures in the mid-1980s
when Congress changed reimbursement with creation of
diagnostic-related groups (DRGs). Today these companies are
leaner and thus better able to survive in a difficult pricing
environment.

Major pharmaceuticals On a relative basis, drug stocks are more
attractively priced than at any time since the price control
hearings of the 1950s. Many companies are actively considering
ways to restructure, merge, or otherwise enhance productivity of
their sales and research efforts. 

Medical services Led by health maintenance organizations, this
has been the best-performing sector in the health care industry.
We believe continued opportunities will arise, driven by further
consolidation among health care providers. In addition,
demographics should favor companies focused on long-term care,
while rising costs are expected to drive continued membership
growth in managed care plans.

The views expressed here are exclusively those of Putnam
Management. They are not meant as investment advice. Although the
companies identified as holdings were viewed favorably as of
February 28, 1994, there is no guarantee the fund will continue
to hold their securities in the future.
<PAGE>
Top 10 holdings*
Abbott Laboratories
Merck & Co., Inc.
Johnson & Johnson
American Home Products 
  Corp.
Pfizer Inc.
United Healthcare Corp.
SmithKline Beecham 
  PLC ADR
Schering Plough Corp.
Medtronic, Inc.
U.S. Healthcare Inc.

*Reflect 43.90% of portfolio, based on net assets as of 2/28/94.
Holdings are subject to change.

(bar chart)
Top industry sectors (based on percentage of net assets as of
2/28/94)

      Ethical Pharmaceuticals    ..........................36.1%
 Medical Supplies and Devices    ...................25.0%
         Hospital Management 
              and Health Care    ................23.5%
                Biotechnology    ....5.1%
<PAGE>
Portfolio of
investments owned
February 28, 1994 (Unaudited)

Common Stocks (95.0%)(a)
Number of Shares                                         Value

Ethical Pharmaceuticals (36.1%)
  300,000  Allergan Inc.                          $  7,050,000
  300,000  American Cyanamid Co.                    13,312,500
  643,000  American Home Products Corp.             38,499,625
  300,000  Bristol-Myers Squibb Co.                 16,575,000
  120,000  Elan Corp. ADR(b)(c)                      4,785,000
  270,000  Forest Laboratories, Inc. 
             Class A(b)                             13,533,750
  100,000  Ivax Corp.                                3,512,500
  250,000  Lilly (Eli) & Co.                        13,781,250
1,267,200  Merck & Co., Inc.                        41,025,600
  120,000  Mylan Laboratories Inc.                   2,820,000
   92,100  Perrigo Co.(b)                            2,670,900
  652,500  Pfizer Inc.                              37,845,000
  118,500  Roberts Pharmaceutical Corp.(b)           3,732,750
  450,000  Schering Plough Corp.                    26,887,500
1,230,000  SmithKline Beecham PLC ADR(c)            33,978,750
  100,000  Syntex Corp.                              1,550,000
  330,000  Upjohn Co.                                9,570,000
  240,000  Warner-Lambert Co.                       15,270,000
                                                   286,400,125

Medical Supplies and Devices (25.0%)
1,860,000  Abbott Laboratories                      51,382,500
  678,300  Bard (C.R.), Inc.                        19,077,188
  783,750  Baxter International Inc.                17,830,312
  170,000  Cordis Corp.(b)                           7,862,500
  300,000  Haemonetics Corp.(b)                      6,675,000
  976,200  Johnson & Johnson                        39,170,025
  300,000  Medtronic, Inc.                          23,925,000
  120,000  Mitek(b)                                  2,100,000
  170,000  Nellcor Inc.(b)                           4,930,000
  125,000  Perseptive Tech II Corp.(b)               3,531,250
   70,000  Sci-Med Life Systems, Inc.(b)          $  2,485,000
  100,000  Sofamor/Danek Group, Inc.(b)              2,800,000
   80,000  St. Jude Medical Inc.                     2,280,000
  448,000  Stryker Corp.                            14,560,000
                                                   198,608,775

Hospital Management and Health Care Services (23.5%)
  750,000  Beverly Enterprises Inc.(b)              11,343,750
  230,000  Caremark International, Inc.              4,973,750
  281,125  Columbia/hca Healthcare Corp.            12,088,375
  300,000  FHP Intl. Corp.(b)                        8,475,000
  300,000  Foundation Health Corp.(b)               11,512,500
  210,000  Health Care & Retirement Corp.(b)         5,460,000
  308,700  Horizon Healthcare Corp.(b)               7,949,025
  800,000  Humana Inc.                              15,600,000
  160,000  Manor Care, Inc.                          4,200,000
  100,000  Medaphis Corp.(b)                         3,675,000
  193,100  National Medical Enterprises, Inc.        3,017,188
   80,000  Oxford Health Plan(b)                     5,160,000
  221,000  Pacificare Health Systems 
             Class B(b)                             11,436,750
  140,000  Quantum Health Resources, 
            Inc.(b)                                  5,285,000
  315,000  U.S. Healthcare Inc.                     20,002,500
  440,000  United Healthcare Corp.                  36,355,000
  295,600  Value Health, Inc.(b)                    12,341,300
  320,000  Vivra, Inc.(b)                            7,760,000
                                                   186,635,138

Biotechnology (5.1%)
  270,000  Amgen Inc.(b)                    $       11,272,500
  156,500  Amylin Pharmaceuticals, Inc.(b)           2,034,500
  350,000  Athena Neurosciences, Inc.(b)             3,193,750
   50,000  Biochem Pharmaceutical, Inc.(b)             556,250
  140,000  Biogen, Inc.(b)                           6,142,500
  260,000  Cor Therapeutics Inc(b)                   3,510,000
  172,500  Genentech, Inc.(b)                        8,430,938
  110,000  Gensia Pharmaceuticals Inc(b)             2,310,000
  133,400  Vertex Pharmaceuticals Inc(b)             2,267,800
                                                    39,718,238

Distribution and Drug Retailing (1.9%)
   67,000  McKesson Corp.                            4,288,000
  430,000  Owens & Minor, Inc.                      11,180,000
                                                    15,468,000

Conglomerates (0.7%)
   60,000  ITT Corp.                                 5,790,000

Computer Software (0.6%)
  178,300  Gmis, Inc.(b)                             2,184,175
  100,000  Shared Medical Systems Corp.              2,675,000
                                                     4,859,175

Electronic Components and Equipment (0.6%)
   65,000  Intel Corp.(b)                            4,468,750

Transportation (0.5%)
   65,000  Burlington Northern, Inc.                 4,086,875

Insurance (0.5%)
  100,000  Lincoln National Corp.               $    4,075,000

Automotive (0.5%)
   65,000  General Motors Corp.                      3,786,250
           Total Common Stocks 
             (cost $639,353,221)                  $753,896,326

Convertible Bonds (0.3%)(a) (cost $1,750,000)
Principal Amount                                         Value
$  1,750,000  Hillhaven (The) Corp. cv. 
             deb. 7 3/4s, 2002(b)               $    2,432,500
Venture Capital Limited Partnership (0.2%) 
(cost $2,090,519)
           Montgomery Medical Ventures ll 
             (Represents an interest in the 
             limited partnership: $568,165 
             invested on 10/30/87, 11/7/88, 
             6/30/89, and 1/5/90, and 
             $151,902 invested on 10/24/90, 
             for a total investment of 
             $2,424,562)(d)                     $    1,891,387

Short-Term Investments (4.6%)(a)
Principal Amount                                         Value
$10,000,000   Ford Motor Credit Co. 3.6s, 
             March 28, 1994                     $    9,977,050
 26,380,000   Interest in $26,380,000 joint 
             repurchase agreement dated 
             February 28, 1993 with Bankers 
             Trust Company due March 1, 
             1994 with respect to various 
             U.S Treasury obligations--
             maturity value of $26,382,513 
             for an effective yield of 3.43%        26,382,513

           Total Short-Term Investments 
             (cost $36,359,563)                  $  36,359,563

           Total Investments 
             (cost $679,553,303)(e)               $794,579,776
<PAGE>
(a) Percentages indicated are based on net assets of $793,361,092
which correspond to a net asset value per share of Class A and
Class B shareholders of $26.65 and 26.48, respectively.

(b) Non-income-producing security.

(c) Securities whose value is determined or significantly
influenced by trading on exchanges not in the United States or
Canada. ADR after the name of a foreign holding stands for
American Depository Receipt, representing foreign securities on
deposit with a domestic custodian bank.

(d) Restricted as to public resale. At the date of acquistion,
this security was valued at cost. The investment in Montgomery
Medical Ventures II represents interest in a limited partnership
which makes investments in companies developing various health
care products and technologies. There were no outstanding
unrestricted securities of the same class as that held. Total
market value of the restricted security owned at February 28,
1994 was $1,891,387 or 0.2% of net assets.

(e) The aggregate identified cost on a tax basis is $679,553,303,
resulting in gross unrealized appreciation and depreciation of
$176,164,778 and $61,138,305, respectively, or net unrealized
appreciation of $115,026,473.
<PAGE>
<TABLE>
<CAPTION>

Statement of
assets and liabilities
February 28, 1994 (Unaudited)

<S>   <C>                                                        <C>
Assets
         Investments in securities, at value (identified cost $679,553,303) 
           (Note 1)                                                        $794,579,776
         Cash                                                                       440
         Dividends and interest receivable                                    1,639,074
         Receivable for securities sold                                       1,408,708
         Receivable for shares of the Fund sold                               1,149,030
         Receivable for foreign tax                                               1,156

             Total assets                                                   798,778,184

Liabilities
         Payable for shares of the Fund repurchased       $2,075,601
         Distribution payable to shareholders                  4,133
         Payable for securities purchased                  1,211,879
         Payable for compensation of Manager (Note 2)      1,332,662
         Payable for administrative services (Note 2)          4,741
         Payable for compensation of Trustees (Note 2)         1,027
         Payable for investor servicing and custodian fees 
           (Note 2)                                          332,278
         Payable for distribution fees (Note 2)              358,852
         Other accrued expenses                               95,919

             Total liabilities                                                5,417,092

         Net assets                                                        $793,361,092

Represented by
         Paid-in capital (Note 4)                                          $673,697,215
         Undistributed net investment income                                  1,571,977
         Accumulated net realized gain on investments                         3,065,427
         Net unrealized appreciation of investments                         115,026,473

         Total -- Representing net assets applicable to capital 
           shares outstanding                                              $793,361,092

Computation of net asset value and offering price 
         Net asset value and redemption price of Class A shares ($755,284,010 
           divided by 28,340,811 shares)                                         $26.65

         Offering price per Class A share (100/94.25 of $26.65)*                 $28.28
         Net asset value and offering price of Class B shares ($ 38,077,082 
           divided by 1,438,070)**                                               $26.48

*On single retail sales of less than $50,000. On sales of $50,000 or more and on group
sales the offering price is reduced.
**Redemption price per share is equal to net asset value less any applicable contingent
deferred sales charge.
/TABLE
<PAGE>
<TABLE>
<CAPTION>

Statement of 
operations

Six months ended February 28, 1994 (Unaudited)

<S>   <C>                                                        <C>
         Investment income:                                         
         Dividends                                                         $  6,899,977
         Interest                                                               934,398
             Total investment income                                          7,834,375

         Expenses:                                                  
         Compensation of manager (Note 2)                 $2,640,326
         Investor servicing and custodian fees (Note 2)      637,727
         Compensation of Trustees (Note 2)                    16,166
         Auditing                                             16,577
         Reports to shareholders                              29,770
         Legal                                                 9,058
         Postage                                              13,753
         Distribution fees -- Class A (Note 2)               968,725
         Distribution fees -- Class B (Note 2)               146,326
         Administrative services (Note 2)                     15,214
         Registration fees                                     7,702
         Other                                                52,517
             Total expenses                                                   4,553,861

         Net investment income                                                3,280,514

         Net realixed gain on investments (Notes 1 and 3)                    25,742,652
         Net unrealized appreciation of investments during the period                  50,863,062

         Net gain on investments                                             76,605,714

         Net increase in net assets resulting from operations               $79,886,228

/TABLE
<PAGE>
<TABLE>
<CAPTION>

Statement of
changes in net assets
<S>   <C>                                                        <C>
                                                    Six months ended         Year ended
                                                         February 28          August 31
                                                               1994*               1993

Increase (decrease) in net assets
         Operations:
         Net investment income                        $    3,280,514     $    8,002,314
         Net realized gain (loss) on investments          25,742,652       (14,644,194)
         Net unrealized appreciation (depreciation) 
           of investments                                 50,863,062       (52,699,200)

         Net increase (decrease) in net assets resulting 
           from operations                                79,886,228       (59,341,080)

         Distributions to shareholders from:                                           
           Net investment income -- Class A              (7,069,791)        (4,451,894)
           Net investment income -- Class B                (218,867)                 --
           Net realized gain on investments -- Class A   (1,502,331)       (74,951,856)
           Net realized gain on investments -- Class B      (60,336)                 --
         Decrease from capital share transactions (Note 4)                 (60,572,299)(48,768,406)

         Total increase (decrease) in net assets          10,462,604      (187,513,236)
         Beginning of year                               782,898,488        970,411,724

         End of year (including undistributed net 
           investment income of 
           $1,571,977 and $9,003,209, respectively)     $793,361,092       $782,898,488

*Unaudited.
/TABLE
<PAGE>
<TABLE>
<CAPTION>

Financial highlights*
(For a share outstanding 
throughout the period)

                    March 1, 1993                  
                       Six Months     (commencement     Six Months
    Ended       of operations) to             Ended
                      February 28         August 31    February 28           Year ended August 31
  1994***                  1993**           1994***           1993       1992
<S>   <C>                     <C>               <C>            <C>        <C>
                Class B                                  Class A  
Net Asset Value, 
  Beginning of Period      $24.28            $24.02         $24.40     $28.31    $31.29

Investment operations
Net Investment Income         .09               .05            .14        .26       .12
Net Realized and Unrealized 
  Gain (Loss) on Investments 2.35               .21           2.40     (1.82)     (.35)

Total from 
  investment operations      2.44               .26           2.54     (1.56)     (.23)

Less Distributions from:
Net Investment Income       (.19)                --          (.24)      (.13)     (.27)
Net Realized Gain on  
  Investments               (.05)                --          (.05)     (2.22)    (2.48)

Total Distributions         (.24)                --          (.29)     (2.35)    (2.75)

Net Asset Value, 
  End of Period            $26.48            $24.28         $26.65     $24.40    $28.31

Total Investment Return at 
  Net Asset Value (%)(b) 20.12(c)           2.16(c)       20.90(c)     (6.45)    (1.12)
<PAGE>
Net Assets, End of Period 
  (in thousands)          $38,077           $18,455       $755,284   $764,443  $970,412

Ratio of Total Expenses to 
  Average Net Assets (%)  1.09(c)           1.91(c)         .64(c)       1.13      1.20
Ratio of Net Investment Income 
  to Average Net 
  Assets (%)             (.83)(c)            .42(c)       (.57)(c)        .91       .61
Portfolio Turnover (%)   14.42(d)          45.46(d)       14.42(d)      45.46     42.12

See page 13 for notes to Financial highlights.
/TABLE
<PAGE>
<TABLE>
<CAPTION>

Financial highlights*(continued)

                                                                     Year ended August 31    
     1991                               1990        1989        1988         1987        1986        1985 
<S>   <C>                                <C>         <C>         <C>          <C>         <C>          <C>
                                                             Class A
Net Asset Value, 
  Beginning of Period                 $22.82      $21.81      $18.55       $24.39      $22.46       $18.47      $15.96

Investment operations
Net Investment Income                    .25         .27         .39       .25(a)         .17          .20         .22
Net Realized and Unrealized 
  Gain (Loss) on Investments            9.07        2.85        5.21       (4.67)        4.70         6.67        2.99

Total from 
  investment operations                 9.32        3.12        5.60       (4.42)        4.87         6.87        3.21

Less Distributions from:
Net Investment Income                  (.35)       (.30)       (.29)        (.12)       (.20)        (.22)       (.16)
Net Realized Gain on Investments       (.50)      (1.81)      (2.05)       (1.30)      (2.74)       (2.66)       (.54)

Total Distributions                    (.85)      (2.11)      (2.34)       (1.42)      (2.94)       (2.88)       (.70)

Net Asset Value, 
  End of Period                       $31.29      $22.82      $21.81       $18.55      $24.39       $22.46      $18.47

Total Investment Return at 
  Net Asset Value (%)(b)               41.99       15.01       34.15      (18.79)       27.68        45.12       21.38

Net Assets, End of Period 
  (in thousands)                    $676,081    $335,080    $270,712     $244,169    $347,540     $289,545    $236,588
<PAGE>
Ratio of Total Expenses to 
  Average Net Assets (%)                1.18        1.18        1.14      1.08(a)        1.03         1.00         .99
Ratio of Net Investment Income 
  to Average Net Assets (%)             1.27        1.44        1.88      1.22(a)         .82         1.01        1.05
Portfolio Turnover (%)                 26.59       37.30       25.11        20.85       33.35        31.14       42.75


*Financial highlights for periods ended through August 31, 1992 have been reclassified and data has been presented to
conform with the requirements issued by the SEC in April, 1993.

**Per share net investment income has been determined on the basis of the weighted average number of shares outstanding
during the period.

***Unaudited.

(a)Reflects an expense limitation during the year ended August 31, 1988. As a result of such limitation, expenses of the
Fund reflect a reduction of $0.02 per share.

(b)Total investment return assumes dividend reinvestment and does not reflect the effect of sales charges.

(c)Annualized.

(d)Not annualized.

/TABLE
<PAGE>
Notes to
Financial statements

February 28, 1994 (Unaudited)

Note 1 Significant accounting policies

The Fund is registered under the Investment Company Act of 1940,
as amended, as a diversified, open-end management investment
company. The investment objective of the Fund is to seek capital
appreciation by investing primarily in the common stocks of
companies in the health sciences industries.

The Fund offers both Class A and Class B shares. The Fund
commenced its public offering of Class B shares on March 1, 1993.
Class A shares are sold with a maximum front-end sales charge of
5.75%. Class B shares do not pay a front-end sales charge but pay
a higher ongoing distribution fee than Class A shares, and may be
subject to a contingent deferred sales charge if those shares are
redeemed within six years of purchase. Expenses of the Fund are
borne pro-rata by the holders of both classes of shares, except
that each class bears expenses unique to that class (including
the distribution fees applicable to such class) and votes as a
class only with respect to its own distribution plan or other
matters on which a class vote is required by law or determined by
the Trustees. Shares of each class would receive their pro-rata
share of the net assets of the Fund, if the Fund were liquidated.
In addition, the Trustees declare separate dividends on each
class of shares.

The following is a summary of significant accounting policies
consistently followed by the Fund in the preparation of its
financial statements. The policies are in conformity with
generally accepted accounting principles.

A) Security valuation Investments for which market quotations are
readily available are stated at market value, which is determined
using the last reported sale price, or, if no sales are reported
- -- as in the case of some securities traded over-the-counter --
the last reported bid price, except that certain U.S. government
obligations are stated at the mean between the last reported bid
and asked prices. Short-term investments having remaining
maturities of 60 days or less are stated at amortized cost, which
approximates market value, and other investments are stated at
fair value following procedures approved by the Trustees. Foreign
securities quoted in foreign currencies are translated into U.S.
dollars at the current exchange rate. The fair value of
restricted securities is determined by the Manager following
procedures approved by the Trustees, and such valuations and
procedures are reviewed periodically by the Trustees.
<PAGE>
B) Joint trading account Pursuant to an exemptive order issued by
the Securities and Exchange Commission, the Fund may transfer
uninvested cash balances into a joint trading account, along with
the cash of other registered investment companies managed by
Putnam Investment Management, Inc. (Putnam Management) (formerly
known as Putnam Management Company, Inc.), the Fund's Manager, a
wholly-owned subsidiary of Putnam Investments, Inc. (formerly
known as The Putnam Companies, Inc.), and certain other accounts.
These balances may be invested in one or more repurchase
agreements and/or short-term money market instruments.

C) Repurchase agreements The Fund or any joint trading account,
through the Fund's custodian, receives delivery of the underlying
securities, the market value of which at the time of purchase is
required to be in an amount at least equal to the resale price,
including accrued interest. The Fund's Manager is responsible for
determining that the value of these underlying securities is at
all times at least equal to the resale price, including accrued
interest.

D) Security transactions and related investment income Security
transactions are accounted for on the trade date (date the order
to buy or sell is executed). Interest income is recorded on the
accrual basis and dividend income is recorded on the ex-dividend
date, except that certain dividends from foreign securities are
recorded as soon as the Fund is informed of the ex-dividend date.

E) Federal taxes It is the policy of the Fund to distribute all
of its income within the prescribed time and otherwise comply
with the provisions of the Internal Revenue Code applicable to
regulated investment companies. It is also the intention of the
Fund to distribute an amount sufficient to avoid imposition of
any excise tax under Section 4982 of the Internal Revenue Code of
1986. Therefore, no provision has been made for federal taxes on
income, capital gains or unrealized appreciation of securities
held and excise tax on income and capital gains.

F) Distributions to shareholders Distributions to shareholders
are recorded by the Fund on the ex-dividend date.

Note 2 Management fee, administrative services, and other
transactions

Compensation of Putnam Management, for management and investment
advisory services is paid quarterly based on the average net
assets of the Fund for the quarter. Such fee is based on the
following annual rates: 0.70% of the first $500 million of
average net assets, 0.60% of the next $500 million, 0.55% of the
next $500 million, and 0.50% of any excess over $1.5 billion,
subject to reduction in any year to the extent that expenses
(exclusive of distribution fees, brokerage, interest and taxes)
of the Fund exceed 2.5% of the first $30 million of average net
assets, 2% of the next $70 million and 1.5% of any excess over
$100 million and by the amount of certain brokerage commissions
and fees (less expenses) received by affiliates of the Manager on
the Fund's portfolio transactions.

The Fund also reimburses the Manager for the compensation and
related expenses of certain officers of the Fund and their staff
who provide administrative services to the Fund. The aggregate
amount of all such reimbursements is determined annually by the
Trustees. For the six months ended February 28, 1994, the Fund
paid $15,214 for these services.

Trustees of the Fund receive an annual Trustee's fee of $2,060
and an additional fee for each Trustees' meeting attended.
Trustees who are not interested persons of the Manager and who
serve on committees of the Trustees receive additional fees for
attendance at certain committee meetings.

Custodial functions for the Fund are provided by Putnam Fiduciary
Trust Company (PFTC), a subsidiary of Putnam Investments, Inc.
Investor servicing agent functions are provided by Putnam
Investor Services, a division of PFTC. Fees paid for these
investor servicing and custodial functions for the six months
ended February 28, 1994 amounted to $ 637,727.

Investor servicing and custodian fees reported in the Statement
of operations for the six months ended February 28, 1994 have
been reduced by credits allowed by PFTC.

The Fund has adopted a distribution plan with respect to its
class A shares (the "class A Plan") pursuant to Rule 12b-1 under
the Investment Company Act of 1940. The purpose of the class A
Plan is to compensate Putnam Mutual Funds Corp., a wholly-owned
subsidiary of Putnam Investments Inc., for services provided and
expenses incurred by it in distributing class A shares. The
Trustees have approved payment by the Fund to Putnam Mutual Funds
Corp. at an annual rate of 0.25% of the average net assets
attributable to class A shares. For the six months ended February
28, 1994, the Fund paid distribution fees of $968,725 for class A
shares.

During the six months ended February 28, 1994, Putnam Mutual
Funds Corp., acting as an underwriter, received net commissions
of $159,708 from the sale of class A shares of the Fund.

A deferred sales charge of up to 1% is assessed on certain
redemptions of class A shares purchased as part of an investment
of $1 million or more. For the six months ended February 28,
1994, Putnam Mutual Funds Corp., acting as an underwriter,
received $9,975 on class A redemptions.

The Fund has adopted a separate distribution plan with respect to
its class B shares (the "class B Plan") pursuant to Rule 12b-1
under the Investment Company Act of 1940. The purpose of the
class B Plan is to compensate Putnam Mutual Funds Corp. for
services provided and expenses incurred by it in distributing
class B shares. The class B Plan provides for payments by the
Fund to Putnam Mutual Funds Corp. at an annual rate of up to
1.00% of the Fund's average net assets attributable to class B
shares. For the six months ended February 28, 1994, the Fund paid
distribution fees of $146,326 for class B shares.

Putnam Mutual Funds Corp. also receives the proceeds of the
contingent deferred sales charges levied on class B share
redemptions within six years of purchase. The charge is based on
declining rates, which begin at 5.00% of the net asset value of
the redeemed shares. Putnam Mutual Funds Corp. received
contingent deferred sales charges of $31,456 from such
redemptions during the six months ended February 28, 1994.

Note 3 Purchases and sales of securities

During the six months ended February 28, 1994, purchases and
sales of investment securities other than short-term investments
aggregated $108,106,015 and $106,376,669, respectively. There
were no purchases or sales of U.S. government obligations during
the year. In determining the net gain or loss on securities sold,
the cost of securities has been determined on the identified cost
basis.
<PAGE>
<TABLE>
<CAPTION>

Note 4 Capital shares

At February 28, 1994, there was an unlimited number of shares of beneficial interest
authorized, divided into two classes, Class A and Class B capital stock. Transactions in
capital shares were as follows:

                           Six months ended                   Year ended
                                February 28                    August 31
                              1994                         1993         
Class A                              Shares        Amount         Shares         Amount
<S>   <C>                               <C>           <C>            <C>
Shares sold                       3,947,796  $101,873,467      7,677,047   $199,120,210
Shares issued in connection with 
  reinvestment of distributions     253,948     6,574,748      2,203,034     60,715,642
4,201,744                       108,448,215     9,880,081    259,835,852
Shares repurchased              (7,192,619) (186,402,132)   (12,825,263)  (327,178,004)
Net decrease                    (2,990,875)$ (77,953,917)    (2,945,182) $ (67,342,152)

                                                           March 1, 1993
                                                           (commencement
                           Six months ended                           of operations) to
                                February 28                    August 31
                               1994                       1993          
Class B                              Shares        Amount         Shares         Amount
Shares sold                         786,290 $  20,172,507        856,829  $  20,939,215
Shares issued in connection with 
  reinvestment of distributions       8,742       225,296             --             --
  795,032                        20,397,803       856,829     20,939,215
Shares repurchased                (116,911)   (3,016,185)       (96,880)    (2,365,469)
Net Increase (decrease)             678,121 $  17,381,618        759,949  $  18,573,746

/TABLE
<PAGE>
Note 5 Reclassification of Capital Accounts

Effective September 1, 1993, Putnam Health Sciences Trust has
adopted the provisions of Statement of Position 93-2
"Determination, Disclosure and Financial Statement Presentation
of Income, Capital Gain and Return of Capital distributions by
Investment Companies (SOP)" The purpose of this SOP is to report
the accumulated net investment income (loss) and accumulated net
realized gain (loss) accounts in such a manner as to approximate
amounts available for future distributions (or to offset future
realized capital gains) and to achieve uniformity in the
presentation of distributions by investment companies. 

As a result of the SOP, the Fund has reclassified reducing
undistributed net investment income by $3,423,088, increasing
accumulated net realized gain by $2,962,679 and increasing
additional paid-in capital by $460,409.

These adjustments represent the cumulated amounts necessary to
report these balances through August 31, 1993, the close of the
fund's most recent fiscal year-end for financial reporting and
tax purposes.

Fund 
performance 
supplement

Putnam Health Sciences Trust is a portfolio managed for capital
appreciation primarily through investments in the health sciences
industries. The Standard & Poor's 500 Index is an unmanaged list
of large capitalization common stocks that assumes reinvestment
of all distributions. The index does not take into account
brokerage commissions or other costs. The fund's portfolio
contains securities that do not match those in the index. The
Consumer Price Index is a commonly used measure of inflation; it
does not represent an investment return.

Fund performance data do not take into account any adjustment
made for class A distribution plan payments made prior to the
plan's inception in 1990 or for taxes that may have been payable
on reinvested distributions.

The fund performance supplement has been prepared by Putnam
Management to provide additional information about the fund and
the indexes used for performance comparisons. The information is
not part of the portfolio of investments owned or the financial
statements.
<PAGE>
Your
Trustees

George Putnam
Chairman
Chairman and President,
The Putnam Funds

William F. Pounds
Vice Chairman
Professor of Management,
Alfred P. Sloan
School of Management,
Massachusetts Institute of
Technology

Jameson Adkins Baxter
President,
Baxter Associates, Inc.

Hans H. Estin
Vice Chairman,
North American
Management Corporation

John A. Hill
Principal and
Managing Director,
First Reserve Corp.

Elizabeth T. Kennan
President,
Mount Holyoke College

Lawrence J. Lasser
President and
Chief Executive Officer,
Putnam Investments, Inc.

Robert E. Patterson
Executive Vice President,
Cabot Partners
Limited Partnership

Donald S. Perkins
Director of various
corporations

George Putnam, III
President, New Generation
Research, Inc.
<PAGE>
A.J.C. Smith
Chairman of the Board
and Chief Executive Officer
Marsh & McLennan
Companies, Inc.

W. Nicholas Thorndike
Director of various
corporations


<PAGE>
Putnam
Health
Sciences
Trust

Fund information

Investment manager
Putnam Investment 
Management, Inc.
One Post Office Square
Boston, MA 02109

Marketing services
Putnam Mutual Funds Corp.
One Post Office Square
Boston, MA 02109

Investor servicing agent
Putnam Investor Services
Mailing address:
P.O. Box 41203
Providence, RI 02940-1203
1-800-225-1581

Custodian
Putnam Fiduciary
Trust Company

Legal counsel
Ropes & Gray

(DALBAR logo)

Putnam Investor Services 
has received the DALBAR 
award each year since the 
award's 1990 inception.
In more than 10,000 tests
of 38 shareholder
service components,
Putnam outperformed
the industry standard
in every category.

OL/63-11526
<PAGE>
Officers

George Putnam
President

Charles E. Porter
Executive Vice President

Patricia C. Flaherty
Senior Vice President

Lawrence J. Lasser
Vice President

Gordon H. Silver
Vice President

Peter Carman
Vice President

John J. Morgan
Vice President

Joanne Soja
Vice President
and Fund Manager

William N. Shiebler
Vice President

John R. Verani
Vice President

Paul O'Neil
Vice President

John D. Hughes
Vice President
and Treasurer

Beverly Marcus
Clerk and 
Assistant Treasurer

This report is for the information 
of shareholders of Putnam Health 
Sciences Trust. It may also be used 
as sales literature when preceded 
or accompanied by the current 
prospectus, which gives details of 
sales charges, investment objectives, 
and operating policies of the fund.



- -------------------
Bulk Rate
U.S. Postage
Paid
Boston, MA
Permit No. 53749
- -------------------

PUTNAMINVESTMENTS
The Putnam Funds
One Post Office Square
Boston, Massachusetts  02109

<PAGE>
APPENDIX TO FORM N30D FILINGS TO DESCRIBE DIFFERENCES BETWEEN
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(4) Because the printed page breaks are not reflected, certain
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differently in this filing. 

(5) Bullet points and similar graphic signals are omitted.


(6) Page numbering is different.

(7) An "(R)" tag has been used in place of the Registered
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