PUTNAM HEALTH SCIENCES TRUST
N-30D, 1994-11-01
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Putnam 
Health 
Sciences 
Trust 

ANNUAL REPORT 
August 31, 1994 

(Art of balance scales)
B O S T O N * L O N D O N * T O K Y O 
<PAGE>

Performance highlights 

> Total returns for the fund's class A and class B shares at net asset value 
  for the one-year period ended August 31, 1994, were 23.38% and 22.49%, 
  respectively, outpacing both the Dow Jones Industrial Average and the 
  Standard & Poor's 500(R) Index.* 

> Lipper ranked the fund's class A shares in the top third of all 
  health/biotechnology funds tracked for one-year total return performance as 
  of August 31, 1994.+ 

> Performance should always be considered in light of a fund's investment 
  strategy. Putnam Health Sciences Trust is designed for investors seeking 
  capital appreciation through investments in the health sciences industries. 

FISCAL 1994 RESULTS AT A GLANCE 

<TABLE>
<CAPTION>
                             Class A                  Class B 
Total return            NAV         POP         NAV          CDSC 
<S>                     <C>         <C>         <C>          <C>
12 months ended 
  8/31/94 (change 
  in 
  value during 
  period 
  plus reinvested 
  distributions)        23.38 %     16.28 %      22.49%       17.49% 
Share value              NAV         POP                        NAV 

8/31/93                $24.40      $25.89                      $24.28 
8/31/94                 29.77       31.59                      29.47 
                                    Capital gains 
Distributions Number Income        Long-       Short- 
                                   term        term           Total 

Class A           1    $ 0.240     $ 0.051         --         $ 0.291 
Class B           1      0.185       0.051         --           0.236 
</TABLE>
Performance data represent past results. For performance over longer periods, 
see pages 8 and 9. POP assumes 5.75% maximum sales charge. CDSC assumes 5% 
maximum contingent deferred sales charge. 

*Performance for the DJIA was 10.25% and the S&P 500, was 5.51%. 

+Lipper Analytical Services is an independent research organization; rankings 
vary over time and do not reflect the effects of sales charges. The fund's 
class A shares ranked 5 out of 16 health/ biotechnology funds for 1 year, 7 
out of 9 for 5 years, and 4 out of 4 for 10 years as of 8/31/94. Past 
performance is not indicative of future results. 
<PAGE>

From the Chairman 

(Photo of George Putnam) 

(c) Karsh, Ottawa 

Dear Shareholder: 

By the time you receive this report, 1994 will be well into the final quarter 
of what is proving to be anything but a quiet year on the investment front. 
The stock market, where your fund concentrates virtually all of its 
attention, has been especially erratic, with unmistakably beneficial effects 
on your fund's performance for the 12 months ended August 31, 1994. 

It is worth cautioning, however, that continued volatility, rather than a new 
sustained rise, is the probable course for stocks--including health care 
stocks--over the months immediately ahead. The Fed will likely continue its 
tight rein on credit until it is convinced that the economy's growth has 
achieved a sustainable rate and inflation fears have been put to rest. 

I am pleased to report that James Giblin has joined Joanne Soja as a 
co-manager of your fund. Jim brings 22 years of investment experience to the 
task. Before joining Putnam in 1993, he was managing director and head of 
Cigna Equity Advisors. 

Respectfully yours, 

(Signature of George Putnam) 

George Putnam 
Chairman of the Trustees 
October 19, 1994 
<PAGE>

Report from the fund managers 
Joanne Soja 
James Giblin 

Putnam Health Sciences Trust's results for the 12 months ended August 31, 
1994, support our current belief that the recent two- year lag in health care 
stock performance has come to an end. It became clear early in 1994 that the 
proposed Clinton health care legislation would eventually be watered down but 
that meanwhile the health care industry had already begun reforming itself. 

It is in this context that we report that the fund produced total returns of 
23.38% and 22.49% for class A and class B shares, respectively, at net asset 
value for the period, compared with the 5.51% average return for stocks 
measured by the Standard & Poor's 500(R) Index. This performance reflects the 
flexibility of investment strategy for the fund during challenging times in 
the market. 

However, as long as uncertainty related to health care reform lingers in the 
market, some volatility in health care stock prices should be expected to 
continue. Consequently, we have been focusing primarily on companies whose 
managements have been quick to respond to a changing environment and to 
offset the inevitable decline in gross profit margins--either through cost 
reductions, restructuring, consolidation, or creative alliances. We have been 
broad-based in our approach, positioning your fund's portfolio in diverse 
subsectors of health care that, in our judgment, have the potential to grow 
regardless of the outcome of health care reform. 

> REPOSITIONING THE FUND FOR INCREASED 
  GROWTH POTENTIAL 
At the start of summer in 1993, the fund's portfolio was positioned 
defensively, approximately 15% in cash and 15% in non-health- care-related 
stocks because of the huge uncertainty resulting from proposed health care 
reform legislation. Values became so depressed, however, that in the fall of 
1993, we began reducing cash levels and increasing the fund's investments in 
the health care sector. 
<PAGE>

While we became more positively inclined toward the stocks because of 
valuations, we were still unsure of the specifics of any legislative actions 
and therefore invested in a diversified mix within the broad health care 
sector. More recently, we decreased the portfolio's cash portion to less than 
5% and reduced investments outside health care to below 4%. We shifted more 
of the portfolio's assets into the medical services companies and continued 
to position the fund opportunistically, targeting companies with attractive 
yields and low price/earnings ratios, and those effecting industry changes to 
improve prospects for growth. 

We see several themes emerging in health care. Companies continue to 
consolidate. Small companies are springing up to answer the information needs 
of the health care industry. Managed care companies have accelerating 
enrollments and better economics continue to fuel their strong earnings 
growth potential. Companies with streamlined cost structures or those with 
unique products and innovative solutions to unmet health care needs continue 
to succeed. 

> HEALTH CARE SERVICES STOCKS HAVE PROVIDED ATTRACTIVE RETURNS 
During the period, health care services stocks were the best- performing 
sector in the health care industry. The sector continues to be led by the 
success of health maintenance organizations (HMOs) that have answered the 
need for high-quality, affordable care. There have also been innovative 
non-HMO approaches bringing into the industry important new technologies and 
services that didn't exist a few years ago--pharmaceutical benefits programs 
and comprehensive provider networks, for example. 

One of the stocks that we increased your fund's position in has been U.S. 
Healthcare Inc. In general, HMOs performed so strongly that we took profits 
across the sector during the period. 
<PAGE>
In our judgment, the health care services sector should be able to maintain 
its heady growth rates and low valuations going forward, continuing to 
deliver attractive returns to your fund's portfolio. 

> PHARMACEUTICAL AND BIOTECHNOLOGY STOCKS BEGIN TO STRENGTHEN 
Large-capitalization pharmaceutical companies began to outperform the market 
in the summer of 1994. We believe this was a function of low relative 
valuations and the absence of dramatic downward earnings revisions following 
first-quarter reports. 

Though high gross profit margins may fall, many companies have prepared 
themselves well for the next year. We primarily seek pharmaceutical companies 
with good long-term product pipelines and those preparing themselves for 
inevitable pricing pressure with strategic realignments or enhanced sales and 
research efforts. 

Your fund has benefited from the consolidation trend. For example, following 
SmithKline Beecham's purchase of the pharmaceutical benefits manager (PBM) 
division of United Healthcare Corp., we tripled the fund's position in 
McKesson Co., which owned a very strong PBM. This PBM was eventually 
purchased by Eli Lilly & Co. for significant performance over the McKesson 
stock price. We are using some of the proceeds from these transactions to 
purchase reasonably valued names like Warner-Lambert Co. and Upjohn Co. The 
stocks of these and other major pharmaceutical companies have yielded 
reasonable total returns. 

Though conservative in our investments in biotechnology, we consider your 
fund appropriately weighted with 5.4% of net assets in this sector as of 
period's end. Stocks of portfolio companies Biogen, Inc., and Genentech, 
Inc., have contributed to portfolio performance. 
<PAGE>
TOP 10 HOLDINGS (8/31/94) 
 Abbott Laboratories 
 Medical supplies and devices 
....................................................
 Johnson & Johnson 
 Medical supplies and devices 
....................................................
 Merck & Co., Inc. 
 Ethical pharmaceuticals 
....................................................
 United Healthcare Corp. 
 Hospital management and health care services 
....................................................
 SmithKline Beecham PLC ADR 
 Ethical pharmaceuticals 
....................................................
 American Home Products Corp. 
 Ethical pharmaceuticals 
....................................................
 Pfizer Inc. 
 Ethical pharmaceuticals 
....................................................
  Medtronic, Inc. 
 Medical supplies and devices 
....................................................
 Schering Plough Corp. 
 Ethical pharmaceuticals 
....................................................
 Warner-Lambert Co. 
 Ethical pharmaceuticals 

These holdings represent 44.2% of the fund's assets. Portfolio holdings are 
subject to change. 

> OUTLOOK: HEALTH CARE OFFERS GROWTH OPPORTUNITIES 
As your fund begins fiscal 1995, we continue broad-based diversification, 
seeking health care companies that offer better products or services at lower 
cost. Many of the same opportunities in health care exist today as did 5 or 
10 years ago. Major disorders like cancer, heart disease, and AIDS call out 
for the promise of new drugs, devices, and therapies. We will aggressively 
pursue those companies that appear to have strong prospects for growth. We 
continue to believe that health care valuations are compelling and that your 
fund retains the potential to continue its outperformance of the general 
market averages into fiscal 1995 and beyond. 

The views expressed about the companies mentioned in this report are 
exclusively those of Putnam Management, and are not meant as investment 
advice. Although the described holdings were viewed favorably as of August 
31, 1994, there is no guarantee the fund will continue to hold these 
securities in the future. 
<PAGE>

Performance summaryThis section provides, at a glance, information about your 
fund's performance. Total return shows how the value of the fund's shares 
changed over time, assuming you held the shares through the entire period and 
reinvested all distributions back into the fund. We show total return in two 
ways: on a cumulative long-term basis and on average how the fund might have 
grown each year over varying periods. For comparative purposes, we show how 
the fund performed relative to appropriate indexes and benchmarks. 

TOTAL RETURN FOR PERIODS ENDED 8/31/94 

<TABLE>
<CAPTION>
                                                                       Standard 
                                 Class A          Class B             & Poor's 
                         NAV         POP        NAV        CDSC      500 Index          CPI 
<S>                   <C>         <C>         <C>         <C>           <C>           <C>
1 year                 23.38%      16.28%     22.49%      17.49%          5.51%        2.90% 
5 years                86.37       75.65        --          --           58.06        19.58 
Annual average         13.26       11.93        --          --            9.59         3.64 
10 years              356.62      330.45        --          --          299.70        42.58 
Annual average         16.40       15.72        --          --           14.86         3.61 
Life of class B 
  (3/1/93)                --        --        23.81       19.81          11.86         4.12 
Annual average            --        --        15.30       12.81           7.76         2.73 
</TABLE>
TOTAL RETURN FOR PERIODS ENDED 9/30/94 
(most recent calendar quarter) 

<TABLE>
<CAPTION>
                                     Class A                 Class B 
                                   NAV         POP         NAV          CDSC 
<S>                             <C>         <C>          <C>           <C>
1 year                           25.01%      17.81%      24.05%        19.05% 
5 years                          87.31       76.54 
Annual average                   13.37       12.04         --            -- 
10 years                        382.28      354.55 
Annual average                   17.04       16.35         --            -- 
Life of class B (3/1/93)          --          --         26.17         22.17 
Annual average                    --          --         15.85         13.51 
</TABLE>
Fund performance data do not take into account any adjustment for taxes 
payable on reinvested distributions or, for class A shares, distribution fees 
prior to implementation of the class A distribution plan in 1990. Performance 
data represent past results. Investment returns and net asset value will 
fluctuate so an investor's shares, when sold, may be worth more or less than 
their original cost. 
<PAGE>
(Graphic Line chart)
GROWTH OF A $10,000 INVESTMENT
Plot Points
Class A    Standard    Consumer
Shares     & Poor's    Price Index
9525       10000       10000 
11442      11823       10335 
16605      16450       10498 
21201      22149       10947 
17218      18165       11388 
23097      25289       11923 
26564      23993       12593 
37718      30469       13072 
37296      32886       13483 
34888      37883       13856 
43045      39970       14258  

(End chart) 

Past performance is no assurance of future results. A $10,000 investment in 
the fund's class B shares at inception on 3/1/93 would have grown to $12,381 
by 8/31/94 ($11,981 with a redemption at the end of the period). 

TERMS AND DEFINITIONS 
Class A shares are generally subject to an initial sales charge. 

Class B shares may be subject to a sales charge upon redemption. 

Net asset value (NAV) is the value of all your fund's assets, minus any 
liabilities, divided by the number of outstanding shares, not including any 
initial or contingent deferred sales charge. 

Public offering price (POP) is the price of a mutual fund share plus the 
maximum sales charge levied at the time of purchase. POP performance figures 
shown here assume the maximum 5.75% sales charge. 

Contingent deferred sales charge (CDSC) is a charge applied at the time of 
the redemption of class B shares and assumes redemption at the end of the 
period. Your fund's CDSC declines from a 5% maximum during the first year to 
1% during the sixth year. After the sixth year, the CDSC no longer applies. 

COMPARATIVE BENCHMARKS 
Standard & Poor's 500 Index is an unmanaged list of common stocks that is 
frequently used as a general measure of stock market performance. The index 
assumes reinvestment of all distributions and does not take into account 
brokerage commissions or other costs. The fund's portfolio contains 
securities that do not match those in the index. 

Consumer Price Index is a commonly used measure of inflation; it does not 
represent an investment return. 
<PAGE>
Life cycle investing

As we move through life, our investment needs change. As 
these needs change, so does the way we allocate our assets. Here are some 
basic rules for setting up and maintaining an investment program and some 
examples of how assets might be allocated. 

> DETERMINE YOUR INVESTMENT OBJECTIVES. 
Objectives may include a new home, college education expenses, or retirement. 

> EVALUATE YOUR RISK TOLERANCE. 
Generally, risk tolerance is higher for younger investors with longer 
timelines and lower for older investors who may depend on their investment 
for current income. 

> ALLOCATE YOUR INVESTABLE SAVINGS. 
Your investment advisor will help you determine how much of your investable 
dollars should be allocated to each investment category. 

> CHOOSE THE APPROPRIATE PUTNAM FUNDS. 
Using Putnam's free exchange privilege, you can adjust your own Putnam 
portfolio of funds as your financial needs change -- without a service fee.* 

Look at the facing page for some ways you can allocate your assets, then turn 
the page to see how the Putnam Family of Funds can help you make your 
choices. 

*Putnam reserves the right to change or terminate the exchange privilege. In 
some cases, a sales charge may apply. See prospectus for details. 
<PAGE>

FOUR WAYS TO ALLOCATE ASSETS 
Your investment advisor can help you determine your objectives, evaluate your 
risk tolerance, and develop a long-term financial plan. These sample 
portfolios can help you diversify your portfolio within the Putnam Family of 
Funds. These illustrations are not intended as investment advice. 

SEEKING MAXIMUM GROWTH 
(Graphic representation of four pie charts)
Risk tolerance:       30%-40% Growth and income -------------- 
Generally 
investors with a 
higher risk           40%-50% Growth -------------- 
tolerance 
(often in their 20s 
and early 30s).       5%-20% Income or -------------- 
                             tax-free income
SEEKING GROWTH AND SOME INCOME 
Risk tolerance:        40%-50% Growth and income -------------- 
Generally 
investors with a       30%-40% Growth -------------- 
high to moderate 
risk tolerance 
(often in their late   10%-30% Income or -------------- 
                               tax-free income
30s and early 40s). 

SEEKING INCOME AND SOME GROWTH 
WITH PROTECTION AGAINST INFLATION 
Risk tolerance:        30%-40% Growth and income -------------- 
Generally 
investors with a       25%-60% Income or --------------  
moderate risk                  tax-free income
tolerance  
(often in their late   10%-20% Growth --------------
40s and 50s). 

SEEKING HIGH CURRENT INCOME AND 
PROTECTION AGAINST INFLATION 
Risk tolerance:         20%-30% Growth and income -------------- 
Generally 
investors with          40%-70% Income or --------------  
a moderate to                   tax-free income
low risk 
tolerance               5%-10% Growth ------------------
(often over 60 
and retired). 
<PAGE>

Putnam Family of Funds 

PUTNAM GROWTH FUNDS 
Asia Pacific Growth Fund 
Diversified Equity Trust 
Europe Growth Fund 
Global Growth Fund 
Health Sciences Trust 
Investors Fund 
Natural Resources Fund* 
New Opportunities Fund 
OTC Emerging Growth Fund 
Overseas Growth Fund 
Vista Fund 
Voyager Fund 

PUTNAM GROWTH AND INCOME FUNDS 
Convertible Income-Growth Trust 
Dividend Growth Fund 
Equity Income Fund 
The George Putnam Fund of Boston 
The Putnam Fund for Growth and Income 
Managed Income Trust 
Utilities Growth and Income Fund 

PUTNAM INCOME FUNDS 

Adjustable Rate U.S. Government Fund 
American Government Income Fund 
Balanced Government Fund 
Corporate Asset Trust 
Diversified Income Trust 
Federal Income Trust 
Global Governmental Income Trust 
High Yield Advantage Fund 
High Yield Trust 
Income Fund 
U.S. Government Income Trust 

Please call your financial advisor or Putnam to obtain a prospectus for any 
Putnam fund. It contains more complete information, including charges and 
expenses. Please read it carefully before you invest or send money. 

PUTNAM TAX-FREE 
INCOME FUNDS 
Intermediate Tax Exempt Fund 
Municipal Income Fund 
Tax Exempt Income Fund 
Tax-Free High Yield Fund 
Tax-Free Insured Fund 
State tax-free income funds+ 

Arizona, California, Florida, Massachusetts, Michigan, Minnesota, New Jersey, 
New York, Ohio, and Pennsylvania 

LIFESTAGE(SM) FUNDS 
Putnam Asset Allocation Funds--three investment portfolios that spread your 
money across a variety of stocks, bonds, and money market investments to help 
maximize your return and reduce your risk. 
The three portfolios: 
Putnam Asset Allocation: Balanced Portfolio 
Putnam Asset Allocation: 
 Conservative Portfolio 
Putnam Asset Allocation: Growth Portfolio 

MOST CONSERVATIVE 
INVESTMENTS++ 

Putnam money market funds: 
Money Market FundS. 
California Tax Exempt Money Market Fund 
New York Tax Exempt Money Market Fund 
Tax Exempt Money Market Fund 
CDs and savings accounts** 

*Formerly Energy-Resources Trust. 

+Not available in all states. 

++Relative to above. 

S.Formerly Daily Dividend Trust. 

**Not offered by Putnam Investments. Certificates of deposit offer a fixed rate 
of return and may be insured, up to certain limits, by federal/state 
agencies. Savings accounts may also be insured up to certain limits. 
<PAGE>

Report of Independent Accountants 
For the fiscal year ended August 31, 1994 
To the Trustees and Shareholders of 
Putnam Health Sciences Trust 

We have audited the accompanying statement of assets and liabilities of 
Putnam Health Sciences Trust, including the portfolio of investments owned, 
as of August 31, 1994, the related statement of operations for the year then 
ended, the statement of changes in net assets for each of the two years in 
the period then ended, and the "Financial Highlights" for each of the ten 
years in the period then ended for class A shares and for the year ended 
August 31, 1994 and for the period March 1, 1993 (commencement of operations) 
to August 31, 1993, for class B shares. These financial statements and 
"Financial Highlights" are the responsibility of the fund's management. Our 
responsibility is to express an opinion on these financial statements and 
"Financial Highlights" based on our audits. 

We conducted our audits in accordance with generally accepted auditing 
standards. Those standards require that we plan and perform the audits to 
obtain reasonable assurance about whether the financial statements and 
"Financial Highlights" are free of material misstatement. An audit includes 
examining, on a test basis, evidence supporting the amounts and disclosures 
in the financial statements. Our procedures included confirmation of 
securities owned as of August 31, 1994, by correspondence with the custodian 
and brokers. An audit also includes assessing the accounting principles used 
and significant estimates made by management, as well as evaluating the 
overall financial statement presentation. We believe that our audits provide 
a reasonable basis for our opinion. 

In our opinion, the financial statements and "Financial Highlights" referred 
to above present fairly, in all material respects, the financial position of 
Putnam Health Sciences Trust as of August 31, 1994, the results of its 
operations for the year then ended, the changes in its net assets for each of 
the two years in the period then ended, and the "Financial Highlights" for 
each of the ten years in the period then ended for class A shares and for the 
year ended August 31, 1994 and for the period March 1, 1993 (commencement of 
operations) to August 31, 1993, for class B shares in conformity with 
generally accepted accounting principles. 

                                                      Coopers & Lybrand L.L.P. 
Boston, Massachusetts 
October 17, 1994 
<PAGE>

Portfolio of investments owned 

August 31, 1994 
<TABLE>
<CAPTION>
COMMON STOCKS (95.3%) (a) 
NUMBER OF SHARES                                                   VALUE 
<S>               <C>                                       <C>
Ethical Pharmaceuticals (35.8%) 
100,000           Affymax N.V.(b)                           $  1,650,000 
350,000           Allergan Inc.                                9,581,250 
180,000           American Cyanamid Co.                       17,370,000 
633,000           American Home Products Corp.                37,584,375 
300,000           Bristol-Myers Squibb Co.                    17,250,000 
120,000           Elan Corp. ADR(b)(c)                         4,320,000 
134,100           Forest Laboratories, Inc. Class 
                  A(b)                                         6,302,700 
100,000           Ivax Corp.                                   1,987,500 
400,000           Lilly (Eli) & Co.                           22,750,000 
1,227,200         Merck & Co., Inc.                           41,878,200 
120,000           Mylan Laboratories Inc.                      3,090,000 
542,500           Pfizer Inc.                                 37,025,625 
370,000           Schering Plough Corp.                       25,853,750 
1,210,000         SmithKline Beecham PLC ADR(c)               37,661,250 
400,000           Upjohn Co.                                  14,450,000 
280,000           Warner-Lambert Co.                          23,415,000 
                                                             302,169,650 
Medical Supplies and Devices (25.9%) 
1,770,000         Abbott Laboratories                         53,100,000 
50,000            Arrow International, Inc.                    1,237,500 
648,300           Bard (C.R.), Inc.                           18,071,363 
763,750           Baxter International Inc.                   21,671,406 
140,000           Cordis Corp.(b)                              7,700,000 
310,000           Haemonetics Corp.(b)                         5,812,500 
910,000           Johnson & Johnson                           45,613,750 
300,000           Medtronic, Inc.                             29,625,000 
120,000           Mitek(b)                                     2,580,000 
170,000           Nellcor Inc.(b)                              5,142,500 
122,000           Perseptive Tech II Corp.(b)                  1,677,500 
84,800            Sci-Med Life Systems, Inc.(b)                3,116,400 
128,000           Sofamor/Danek Group, Inc.(b)                 2,576,000 
125,000           St. Jude Medical Inc.                        4,312,500 
478,000           Stryker Corp.                               16,969,000 
                                                             219,205,419 
Hospital Management and Medical Services (22.5%) 
65,000            Apogee, Inc.(b)                              1,235,000 
630,000           Beverly Enterprises Inc.(b)                  8,583,750 
291,125           Columbia/HCA Healthcare Corp.               12,372,813 
75,000            Express Scripts, Inc. Class A(b)             2,587,500 
235,000           FHP Intl. Corp.(b)                           6,345,000 
100,000           Foundation Health Corp.(b)                   3,787,500 
210,000           Health Care & Retirement Corp. (b)           5,853,750 
250,000           Horizon Healthcare Corp.(b)                  6,343,750 
800,000           Humana Inc.                                 17,000,000 
190,000           Manor Care, Inc.                             5,225,000 
</TABLE>

<TABLE>
<CAPTION>
 COMMON STOCKS 

NUMBER OF SHARES                                                                        VALUE 
<S>                 <C>                                                          <C>
Hospital Management and Medical Services (continued) 
170,000             Medaphis Corp.(b)                                            $  5,992,500 
100,000             Mid Atlantic Medical Services, Inc.(b)                          2,650,000 
193,100             National Medical Enterprises, Inc.                              3,524,075 
40,000              Oxford Health Plan(b)                                           2,830,000 
171,000             Pacificare Health Systems Class B(b)                           11,756,250 
160,000             Quantum Health Resources, Inc.(b)                               5,740,000 
183,900             Quorum Health(b)                                                3,379,162 
472,500             U.S. Healthcare Inc.                                           20,435,625 
800,000             United Healthcare Corp.                                        41,800,000 
295,600             Value Health, Inc.(b)                                          14,558,300 
320,000             Vivra, Inc.                                                     8,200,000 
                                                                                  190,199,975 
Biotechnology (5.4%) 
280,000             Amgen Inc.(b)                                                  14,770,000 
156,500             Amylin Pharmaceuticals, Inc.(b)                                 1,252,000 
350,000             Athena Neurosciences, Inc.(b)                                   2,318,750 
50,000              Biochem Pharmaceutical, Inc.(b)                                   525,000 
140,000             Biogen, Inc.(b)                                                 7,052,500 
260,000             Cor Therapeutics Inc.(b)                                        3,835,000 
172,500             Genentech, Inc.(b)                                              8,862,188 
210,000             Gensia Pharmaceuticals Inc.(b)                                  2,362,500 
90,100              Quintiles Transnational Corp.(b)                                2,353,862 
133,400             Vertex Pharmaceuticals Inc(b)                                   1,917,625 
                                                                                   45,249,425 
Computer Software (1.3%) 
91,600              Cerner Corp.(b)                                                 3,824,300 
220,000             GMIS, Inc.(b)                                                   2,970,000 
170,000             Shared Medical Systems Corp.                                    4,250,000 
                                                                                   11,044,300 
Distribution and Drug Retailing (1.1%) 
645,000             Owens & Minor, Inc.                                             9,513,750 
Insurance (0.7%) 
90,000              Lincoln National Corp.                                          3,465,000 
208,200             Rightchoice Managed Care, Inc. Class A(b)                       2,394,300 
                                                                                    5,859,300 
Electronic Components and Equipment (0.5%) 
65,000              Intel Corp.                                                     4,273,750 
Conglomerates (0.5%) 
50,000              ITT Corp.                                                       4,100,000 
Pharmaceuticals (0.5%) 
118,500             Roberts Pharmaceutical Corp.(b)                                 3,999,375 
Health Care (0.4%) 
200,000             Medisense Inc.(b)                                               3,550,000 
Automotive (0.4%) 
65,000              General Motors Corp.                                            3,266,250 
<PAGE>

Transportation (0.3%) 
55,000              Burlington Northern Inc.                                     $  2,887,500 
                    Total Common Stocks (cost $618,506,529)                      $805,318,694 
CONVERTIBLE BONDS (0.3%) (cost $1,750,000) 
PRINCIPAL AMOUNT                                                                        VALUE 
$1,750,000          Hillhaven (The) Corp. cv. deb. 7-3/4s, 2002(b)               $  2,301,250 
VENTURE CAPITAL LIMITED PARTNERSHIP (0.2%) (a)(b)(d) (cost $2,424,562) 
                    Montgomery Medical Ventures ll (Represents an 
                    interest in the limited partnership: $600,000 
                    invested on 10/30/87, 11/7/88, 6/30/89, and 1/5/90, 
                    and $24,562 invested on 10/24/90, for a total 
                    investment of $2,424,562)                                    $  1,620,024 
SHORT-TERM INVESTMENTS (4.4%)(a) 
PRINCIPAL AMOUNT                                                                        VALUE 
$10,000,000         Federal Home Loan Banks 4.62s, September 26, 1994            $  9,967,916 
27,350,000          Interest in $300,000,000 joint repurchase agreement 
                    dated August 31, 1994 with Bankers Trust Company due 
                    September 1, 1994 with respect to various U.S 
                    Treasury obligations-- maturity value of $27,353,639 
                    for an effective yield of 4.79%                                27,353,639 
                    Total Short-Term Investments 
                    (cost $37,321,555)                                           $ 37,321,555 
                    Total Investments 
                    (cost $660,002,646) (e)                                      $846,561,523 
</TABLE>
(a) Percentages indicated are based on net assets of $845,021,870 which 
correspond to a net asset value for class A and class B shares of $29.77 and 
$29.47, respectively. 

(b) Non-income-producing security. 

(c) Securities whose value is determined or significantly influenced by 
trading on exchanges not in the United States or Canada. ADR after the name 
of a foreign holding stands for American Depository Receipt, representing 
foreign securities on deposit with a domestic custodian bank. 

(d) Restricted as to public resale. At the date of acquisition, these 
securities were valued at cost. The investment in Montgomery Medical Ventures 
II represents interest in a limited partnership which makes investments in 
companies developing various health care products and technologies. There 
were no outstanding unrestricted securities of the same class as those held. 
Total market value of restricted securities owned at August 31, 1994 was 
$1,620,024 or 0.2% of net assets. 

(e) The aggregate identified cost on a federal income tax basis is 
$660,015,944 resulting in gross unrealized appreciation and depreciation of 
$225,813,321 and $39,267,742 respectively, or net unrealized appreciation of 
$186,545,579. 
  The accompanying notes are an integral part of these financial statements. 
<PAGE>

Statement of assets and liabilities 
August 31, 1994 
<TABLE>
<CAPTION>
 Assets 
<S>                                                                                 <C>
Investments in securities, at value (identified cost $660,002,646) (Note 1)         $846,561,523 
Cash                                                                                         381 
Dividends and interest receivable                                                      2,104,033 
Receivable for shares of the fund sold                                                 1,979,172 
Total assets                                                                        $850,645,109 
Liabilities 
Payable for shares of the fund repurchased                                          $  2,341,076 
Payable for securities purchased                                                       1,443,800 
Payable for compensation of Manager (Note 2)                                           1,288,537 
Payable for administrative services (Note 2)                                               2,831 
Payable for compensation of Trustees (Note 2)                                                583 
Payable for investor servicing and custodian fees (Note 2)                               127,603 
Payable for distribution fees (Note 2)                                                   350,611 
Other accrued expenses                                                                    68,198 
Total liabilities                                                                      5,623,239 
Net assets                                                                          $845,021,870 
Represented by 
Paid-in capital (Notes 1, 4 and 5)                                                  $638,357,486 
Undistributed net investment income (Notes 1 and 5)                                    5,522,832 
Accumulated net realized gain on investment (Notes 1 and 5)                           14,582,675 
Net unrealized appreciation of investments                                           186,558,877 
Total--Representing net assets applicable 
  to capital shares outstanding                                                     $845,021,870 
</TABLE>

<TABLE>
<CAPTION>
<S>                                                                         <C>
 Computation of net asset value and offering price 
Net asset value and redemption price 
  of class A shares ($789,597,994 divided by 26,520,524 
  shares)                                                                   $29.77 
Offering price per class A share (100/94.25 of $29.77)*                     $31.59 
Net asset value and offering price of class B shares 
  ($55,423,876 divided by 1,880,595 shares)+                                $29.47 
</TABLE>
* On single retail sales of less than $50,000. On sales of $50,000 or more 
and on group sales the offering price is reduced. 

+ Redemption price per share is equal to net asset value less any applicable 
contingent deferred sales charge. 

  The accompanying notes are an integral part of these financial statements. 
<PAGE>

Statement of operations 
Year ended August 31, 1994 
<TABLE>
<CAPTION>
<S>                                                     <C>
 Investment income: 
Dividends                                               $ 14,857,814 
Interest                                                   1,473,048 
Total investment income                                   16,330,862 
Expenses: 
Compensation of Manager (Note 2)                           5,195,028 
Investor servicing and custodian fees (Note 2)             1,185,145 
Compensation of Trustees (Note 2)                             31,108 
Auditing                                                      28,375 
Legal                                                         23,283 
Postage                                                      108,050 
Reports to shareholders                                       66,679 
Distribution fees--class A (Note 2)                        1,863,170 
Distribution fees--class B (Note 2)                          361,785 
Administrative services (Note 2)                              21,952 
Registration fees                                              7,902 
Other                                                        169,139 
Total expenses                                             9,061,616 
Net investment income                                      7,269,246 
Net realized gain on investments (Notes 1 and 3)          37,397,500 
Net unrealized appreciation of investments during 
  the year                                               122,395,466 
Net gain on investments                                  159,792,966 
Net increase in net assets resulting from 
  operations                                            $167,062,212 
</TABLE>
  The accompanying notes are an integral part of these financial statements. 
<PAGE>

Statement of changes in net assets 
<TABLE>
<CAPTION>
                                                                                  Year ended 
                                                                                   August 31 
                                                                   1994                 1993 
<S>                                                        <C>                 <C>
Increase (decrease) in net assets 
Operations: 
Net investment income                                      $  7,269,246        $   8,002,314 
Net realized gain (loss) on investments                      37,397,500          (14,644,194) 
Net unrealized appreciation (depreciation) of 
  investments                                               122,395,466          (52,699,200) 
Net increase (decrease) in net assets resulting from 
  operations                                                167,062,212          (59,341,080) 
Distributions to shareholders from: 
Net investment income 
Class A                                                      (7,054,011)          (4,451,894) 
Class B                                                        (218,378)             -- 
Net realized gain on investments 
Class A                                                      (1,518,110)         (74,951,856) 
Class B                                                         (60,825)             -- 
Decrease from capital share transactions (Note 4)           (96,087,506)         (48,768,406) 
Total increase (decrease) in net assets                      62,123,382         (187,513,236) 
Net assets 
Beginning of year                                           782,898,488          970,411,724 
End of year (including undistributed net investment 
  income of $5,522,832 and $9,003,209, respectively)       $845,021,870        $ 782,898,488 
</TABLE>
  The accompanying notes are an integral part of these financial statements. 
<PAGE>

Financial Highlights 
(For a share outstanding throughout the period) 

<TABLE>
<CAPTION>
                                                              March 1, 1993 
                                                           (commencement of 
                                          Year ended         operations) to 
                                           August 31              August 31                Year ended August 31 
                                                1994                1993*                  1994            1993 
                                                                    Class B                             Class A 
<S>                                          <C>                    <C>                <C>             <C>
Net asset value, 
  beginning of period                        $ 24.28                $ 24.02            $  24.40        $  28.31 
Investment operations 
Net investment income                            .10                    .05                 .30             .26 
Net realized and unrealized gain 
  (loss) on investments                         5.33                    .21                5.36           (1.82) 
Total from investment operations                5.43                    .26                5.66           (1.56) 
Less distributions from: 
Net investment income                           (.19)                  --                  (.24)           (.13) 
Net realized gain on investments                (.05)                  --                  (.05)          (2.22) 
Total distributions                             (.24)                  --                  (.29)          (2.35) 
Net asset value, end of period               $ 29.47                $ 24.28            $  29.77        $  24.40 
Total investment return at net asset 
  value (%) (b)                                22.49                  (1.08)(c)           23.38           (6.45) 
Net assets, end of period 
  (in thousands)                             $55,424                $18,455            $789,598        $764,443 
Ratio of total expenses to average 
  net assets (%)                                1.87                    .96(c)             1.12            1.13 
Ratio of net investment income to 
  average net assets (%)                         .24                    .21(c)              .96             .91 
Portfolio turnover (%)                         23.18                  45.46               23.18           45.46 
</TABLE>
<PAGE>

<TABLE>
<CAPTION>
                                              Year ended August 31 
        1992          1991          1990          1989          1988          1987          1986            1985 
                                                                                                         Class A 
<S>                <C>           <C>           <C>           <C>           <C>           <C>             <C>
$  31.29          $  22.82      $  21.81      $  18.55      $  24.39      $  22.46      $  18.47        $  15.96 

     .12               .25           .27           .39           .25(a)        .17           .20             .22 

    (.35)             9.07          2.85          5.21         (4.67)         4.70          6.67            2.99 
    (.23)             9.32          3.12          5.60         (4.42)         4.87          6.87            3.21 

    (.27)             (.35)         (.30)         (.29)         (.12)         (.20)         (.22)           (.16) 
   (2.48)             (.50)        (1.81)        (2.05)        (1.30)        (2.74)        (2.66)           (.54) 
   (2.75)             (.85)        (2.11)        (2.34)        (1.42)        (2.94)        (2.88)           (.70) 
$  28.31          $  31.29      $  22.82      $  21.81      $  18.55      $  24.39      $  22.46        $  18.47 

   (1.12)            41.99         15.01         34.15        (18.79)        27.68         45.12           21.38 

$970,412          $676,081      $335,080      $270,712      $244,169      $347,540      $289,545        $236,588 

    1.20              1.18          1.18          1.14          1.08(a)       1.03          1.00             .99 

     .61              1.27          1.44          1.88          1.22(a)        .82          1.01            1.05 
   42.12             26.59         37.30         25.11         20.85         33.35         31.14           42.75 
</TABLE>
* Per-share net investment income has been determined on the basis of the 
weighted average number of shares 
outstanding during the period. 
(a) Reflects an expense limitation during the year ended August 31, 1988. As 
a result of such limitation, expenses of 
the fund reflect a reduction of $0.02 per share. 
(b) Total investment return assumes dividend reinvestment and does not 
reflect the effect of sales charges. 
(c) Not annualized. 
<PAGE>

Notes to financial statements 
August 31, 1994 

Note 1 
Significant accounting policies 

The fund is registered under the Investment Company Act of 1940, as amended, 
as a diversified, open-end management investment company. The investment 
objective of the fund is to seek capital appreciation by investing primarily 
in the common stocks of companies in the health sciences industries. 

The fund offers both class A and class B shares. Class A shares are sold with 
a maximum front-end sales charge of 5.75%. Class B shares do not pay a 
front-end sales charge but pay a higher ongoing distribution fee than class A 
shares, and may be subject to a contingent deferred sales charge if those 
shares are redeemed within six years of purchase. Expenses of the fund are 
borne pro-rata by the holders of both classes of shares, except that each 
class bears expenses unique to that class (including the distribution fees 
applicable to such class) and votes as a class only with respect to its own 
distribution plan or other matters on which a class vote is required by law 
or determined by the Trustees. Shares of each class would receive their pro- 
rata share of the net assets of the fund, if the fund were liquidated. In 
addition, the Trustees declare separate dividends on each class of shares. 

The following is a summary of significant accounting policies consistently 
followed by the fund in the preparation of its financial statements. The 
policies are in conformity with generally accepted accounting principles. 

A) Security valuation Investments for which market quotations are readily 
available are stated at market value, which is determined using the last 
reported sale price, or, if no sales are reported--as in the case of some 
securities traded over-the-counter-- the last reported bid price, except that 
certain U.S. government obligations are stated at the mean between the last 
reported bid and asked prices. Short- term investments having remaining 
maturities of 60 days or less are stated at amortized cost, which 
approximates market value, and other investments are stated at fair value 
following procedures approved by the Trustees. Foreign securities quoted in 
foreign currencies are translated into U.S. dollars at the current exchange 
rate. The fair value of restricted securities is determined by the Manager 
following procedures approved by the Trustees, and such valuations and 
procedures are reviewed periodically by the Trustees. 

B) Joint trading account Pursuant to an exemptive order issued by the 
Securities and Exchange Commission, the fund may transfer uninvested cash 
balances into a joint trading account, along with the cash of other 
registered investment companies managed by Putnam Investment Management, Inc. 
(Putnam Management), the fund's Manager, a wholly owned subsidiary of Putnam 
Investments, Inc. and certain other accounts. These balances may be invested 
in one or more repurchase agreements and/or short-term money market 
instruments. 

C) Repurchase agreements The fund or any joint trading account, through the 
fund's custodian, receives delivery of the underlying securities, the market 
value of which at the time of purchase is required to be in an amount at 
least equal to the resale 
<PAGE>

price, including accrued interest. The fund's Manager is responsible for 
determining that the value of these underlying securities is at all times at 
least equal to the resale price, including accrued interest. 

D) Security transactions and related investment income Security transactions 
are accounted for on the trade date (date the order to buy or sell is 
executed). Interest income is recorded on the accrual basis and dividend 
income is recorded on the ex-dividend date, except that certain dividends 
from foreign securities are recorded as soon as the fund is informed of the 
ex-dividend date. 

E) Federal taxes It is the policy of the fund to distribute all of its income 
within the prescribed time and otherwise comply with the provisions of the 
Internal Revenue Code applicable to regulated investment companies. It is 
also the intention of the fund to distribute an amount sufficient to avoid 
imposition of any excise tax under Section 4982 of the Internal Revenue Code 
of 1986. Therefore, no provision has been made for federal taxes on income, 
capital gains or unrealized appreciation of securities held, and excise tax 
on income and capital gains. 

F) Distributions to shareholders Distributions to shareholders are recorded 
by the fund on the ex-dividend date. 

The amount and character of income and gains to be distributed are determined 
in accordance with income tax regulations which may differ from generally 
accepted accounting principles. These differences include treatment of wash 
sales, foreign currency gains and losses, and post October loss deferrals. 
Reclassifications are made to the fund's capital accounts to reflect income 
and gains available for distribution (or available capital loss carryovers) 
under income tax regulations. For the year ended August 31, 1994, the fund 
reclassified $54,146 to decrease undistributed net investment income, 
$121,331 to decrease accumulated net realized gain on investments, and 
$175,477 to increase paid-in capital. 

Note 2 
Management fee, administrative services, and other transactions 
Compensation of Putnam Management for management and investment advisory 
services is paid quarterly based on the average net assets of the fund for 
the quarter. Such fee is based on the following annual rates: 0.70% of the 
first $500 million of average net assets, 0.60% of the next $500 million, 
0.55% of the next $500 million, and 0.50% of any amount over $1.5 billion, 
subject under current law, to reduction in any year to the extent that 
expenses (exclusive of distribution fees, brokerage, interest and taxes) of 
the fund exceed 2.5% of the first $30 million of average net assets, 2% of 
the next $70 million and 1.5% of any excess over $100 million and by the 
amount of certain brokerage commissions and fees (less expenses) received by 
affiliates of the Manager on the fund's portfolio transactions. 

The fund also reimburses the Manager for the compensation and related 
expenses of certain officers of the fund and their staff who provide 
administrative services to the fund. The aggregate amount of all such 
reimbursements is determined annually by the Trustees. For the year ended 
August 31, 1994, the fund paid $21,952 for these services. 

Trustees of the fund receive an annual Trustee's fee of $1,750 and an 
additional fee for each Trustees' meeting attended. Trustees who are not 
interested persons of the Manager and who serve on committees of the Trustees 
receive additional fees for attendance at certain committee meetings. 

Custodial functions for the fund are provided by Putnam Fiduciary Trust 
<PAGE>
Company (PFTC), a subsidiary of Putnam Investments, Inc. Investor servicing 
agent functions are provided by Putnam Investor Services, a division of PFTC. 
Fees paid for these investor servicing and custodial functions for the year 
ended August 31, 1994 amounted to $1,185,145. 

Investor servicing and custodian fees reported in the Statement of operations 
for the year ended August 31, 1994, have been reduced by credits allowed by 
PFTC. 

The fund has adopted a distribution plan with respect to its class A shares 
(the "Class A Plan") pursuant to Rule 12b-1 under the Investment Company Act 
of 1940. The purpose of the Class A Plan is to compensate Putnam Mutual Funds 
Corp., a wholly owned subsidiary of Putnam Investments, Inc., for services 
provided and expenses incurred by it in distributing class A shares. The 
Trustees have approved payment by the fund to Putnam Mutual Funds Corp. at an 
annual rate of 0.25% of the average net assets attributable to class A 
shares. For the year ended August 31, 1994, the fund paid distribution fees 
of $1,863,170 for class A shares. 

During the year ended August 31, 1994, Putnam Mutual Funds Corp., acting as 
the underwriter, received net commissions of $253,932 from the sale of class 
A shares of the fund. 

A deferred sales charge of up to 1.00% is assessed on certain redemptions of 
class A shares purchased as part of an investment of $1 million or more. For 
the year ended August 1994, Putnam Mutual Funds Corp., acting as the 
underwriter, received $10,477 on class A redemptions. 

The fund has adopted a separate distribution plan with respect to its class B 
shares (the "Class B Plan") pursuant to Rule 12b-1 under the Investment 
Company Act of 1940. The purpose of the Class B Plan is to compensate Putnam 
Mutual Funds Corp. for services provided and expenses incurred by it in 
distributing class B shares. The Class B Plan provides for payments by the 
fund to Putnam Mutual Funds Corp. at an annual rate of 1.00% of the fund's 
average net assets attributable to class B shares. For the year ended August 
31, 1994, the fund paid distribution fees of $361,785 for class B shares. 

Putnam Mutual Funds Corp. also receives the proceeds of the contingent 
deferred sales charges levied on class B share redemptions within six years 
of purchase. The charge is based on declining rates, which begin at 5.00% of 
the net asset value of the redeemed shares. Putnam Mutual Funds Corp. 
received contingent deferred sales charges of $102,556 from such redemptions 
for the year ended August 31, 1994. 

Note 3 
Purchases and sales of securities 
During the year ended August 31, 1994, purchases and sales of investment 
securities other than short-term investments aggregated $169,903,431 and 
$200,336,070, respectively. There were no purchases or sales of U.S. 
government obligations during the year. In determining the net gain or loss 
on securities sold, the cost of securities has been determined on the 
identified cost basis. 

Note 4 
Capital shares 
At August 31, 1994, there was an unlimited number of shares of beneficial 
interest authorized, divided into two classes, class A and class B capital 
shares. Transactions in capital shares were as follows: 
<PAGE>

<TABLE>
<CAPTION>
                                                                           Year ended August 31 
                                                    1994                                   1993 
Class A                         Shares            Amount            Shares               Amount 
<S>                         <C>             <C>                 <C>               <C>
Shares sold                  6,392,086     $ 167,778,186         7,677,047        $ 199,120,210 
Shares issued in 
  connection with 
  reinvestment of 
  distributions                254,000         6,576,169         2,203,034           60,715,642 
                             6,646,086       174,354,355         9,880,081          259,835,852 
Shares repurchased         (11,457,249)     (299,677,276)      (12,825,263)        (327,178,004) 
Net decrease                (4,811,163)    $(125,322,921)       (2,945,182)       $ (67,342,152) 
</TABLE>

<TABLE>
<CAPTION>
                                                                                   March 1, 1993 
                                                                                (commencement of 
                                                                                  operations) to 
                                        Year ended August 31                           August 31 
                                                        1994                                1993 
Class B                           Shares              Amount        Shares                Amount 
<S>                            <C>               <C>               <C>               <C>
Shares sold                    1,447,812         $37,873,012       856,829           $20,939,215 
Shares issued in 
  connection with 
  reinvestment of 
  distributions                    8,743             225,304          --                  -- 
                               1,456,555          38,098,316       856,829            20,939,215 
Shares repurchased              (335,909)         (8,862,901)      (96,880)           (2,365,469) 
Net increase                   1,120,646         $29,235,415       759,949           $18,573,746 
</TABLE>
Note 5 
Reclassification of Capital Accounts 

Effective September 1, 1993, Putnam Health Sciences Trust has adopted the 
provisions of Statement of Position 93-2 "Determination, Disclosure and 
Financial Statement Presentation of Income, Capital Gain and Return of 
Capital distributions by Investment Companies (SOP)." The purpose of this SOP 
is to report the accumulated net gain (loss) accounts in such a manner as to 
approximate amounts available for future distributions (or to offset future 
realized capital gains) and to achieve uniformity in the presentation of 
distributions by investment companies. 

As a result of the SOP, the fund has reclassified to reduce undistributed net 
investment income by $3,423,088 to increase accumulated net realized gain by 
$2,962,679, and increasing additional paid-in capital by $460,409. 

Reclassifications represent the cumulative amounts necessary to report these 
balances through August 31, 1993, the close of the fund's prior fiscal 
year-end for financial reporting and tax purposes. 
<PAGE>
Federal Tax Information 

The distribution of $0.24 and $0.185 per share for class A and class B 
shares, respectively, paid in December 1993 from investment income was 
designated as "dividend income" for federal income tax purposes. The fund has 
designated 100% of the investment income as qualifying for the 
dividends-received deduction for corporations. 

In addition, the fund paid a distribution of $0.051 per share for class A and 
class B shares in December 1993 classified as "long-term capital gain," 
whether received in cash or additional fund shares, and regardless of how 
long you had owned your shares before the distribution was made. 

The Form 1099 you receive in January 1995 will show you the tax status of all 
distributions paid to your account in calendar 1994. 
Fund information 
<PAGE>

INVESTMENT MANAGER 

Putnam Investment 
Management, Inc. 
One Post Office Square 
Boston, MA 02109 

MARKETING SERVICES 
Putnam Mutual Funds Corp. 
One Post Office Square 
Boston, MA 02109 

CUSTODIAN 
Putnam Fiduciary Trust Company 

LEGAL COUNSEL 
Ropes & Gray 

INDEPENDENT ACCOUNTANTS 
Coopers & Lybrand L.L.P. 

TRUSTEES 
George Putnam, Chairman 
William F. Pounds, Vice Chairman 
Jameson Adkins Baxter 
Hans H. Estin 
John A. Hill 
Elizabeth T. Kennan 
Lawrence J. Lasser 
Robert E. Patterson 
Donald S. Perkins 
George Putnam, III 
A.J.C. Smith 
W. Nicholas Thorndike 

OFFICERS 
George Putnam 
President 

Charles E. Porter 
Executive Vice President 

Patricia C. Flaherty 
Senior Vice President 

John R. Verani 
Vice President 

Lawrence J. Lasser 
Vice President 

Gordon H. Silver 
Vice President 

Peter Carman 
Vice President 

Brett C. Browchuk 
Vice President 

John J. Morgan, Jr. 
Vice President 

Joanne Soja 
Vice President and Fund Manager 

James Giblin 
Vice President and Fund Manager 

William N. Shiebler 
Vice President 

Paul M. O'Neil 
Vice President 

John D. Hughes 
Vice President and Treasurer 

Beverly Marcus 
Clerk and Assistant Treasurer 

This report is for the information of shareholders of Putnam Health 
Sciences Trust. It may also be used as sales literature when preceded or 
accompanied by the current prospectus, which gives details of sales charges, 
investment objectives, and operating policies of the fund, and the most 
recent copy of the Putnam Quarterly Performance Summary. 
<PAGE>

PUTNAM INVESTMENTS 
The Putnam Funds 
One Post Office Square 
Boston, Massachusetts 02109 

..................
Bulk Rate 
U.S. Postage Paid 
Boston, MA 
Permit No. 53749 
..................

021/335/14155

<PAGE>

APPENDIX TO FORM N-30D FILINGS TO DESCRIBE DIFFERENCES BETWEEN PRINTED
AND EDGAR-FILED TEXTS:

(1)  Bold and italic typefaces are displayed in normal type.

(2)  Headers (e.g., the name of the fund) are omitted.

(3)  Certain tabular and columnar headings and symbols are displayed 
     differently in this filing.

(4)  Bullet points and similar graphic signals are omitted.

(5)  Page numbering is omitted.

(6)  Trademark symbol replaced with (TM)



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