PUTNAM HEALTH SCIENCES TRUST
N-30D, 1996-05-01
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Putnam
Health 
Sciences
Trust

[GRAPHIC OMITTED: ARTWORK]

SEMIANNUAL REPORT

February 29, 1996

[LOGO:  BOSTON * LONDON * TOKYO]



Fund highlights


*  Morningstar, Inc., an independent rating agency, once again awarded 
Putnam Health Sciences Trust four out of a possible five stars for the 
overall risk-adjusted performance of its class A shares as of March 31, 
1996 (based on the fund's average annual returns for the 3-, 5-, and 10-
year periods). Only 22.5% of the 1,469 equity funds rated received four 
stars.*


*  "In managing Putnam Health Sciences Trust we rely on Putnam's 
extensive research capabilities in our search for attractive investment 
opportunities within this dynamic field. Indeed, we believe the health-
care industry encompasses a broad array of possibilities for investors."

                                            - Joanne Soja, Fund Manager

CONTENTS

 4     Report from Putnam Management
10     Fund performance summary
13     Portfolio holdings
17     Financial statements

 * Morningstar ratings are subject to change every month and are 
calculated from a fund's 3-, 5-, and 10-year average annual returns in 
excess of 90-day Treasury bill returns, with appropriate sales charge 
adjustments and a risk factor that reflects performance compared to 90-
day Treasury bill monthly returns. For 3-, 5-, and 10-year performance, 
the fund received 5, 2, and 5 stars, respectively. There were 1,469, 
970, and 517 funds rated. 10% of the funds in an investment category 
receive 5 stars; 22.5% receive 4 stars; and 35% receive 3 stars. 
Performance for other shares classes will vary. Past performance is not 
indicative of future results.



[GRAPHIC OMITTED: photo of George Putnam]

(copyright) Karsh, Ottawa

From the Chairman

Dear Shareholder:

Putnam Health Sciences Trust began its new fiscal year during one of the 
strongest stock market advances in recent memory. The extent of the 
market's rise and management's adept positioning of the portfolio in our 
opinion are clearly reflected in your fund's results during the six 
months ended February 29, 1996.

While we are pleased with the fund's performance, the stock market's 
sharp drop just after the period's close served as an abrupt reminder 
that even the strongest markets will take an occasional pause. Indeed, 
more turbulence may lie ahead; Putnam Management nevertheless believes 
there is still some life in the market's broad advance.

Fund Manager Joanne Soja, however, looks beyond the market's short-term 
ups and downs as she pursues the fund's objective of seeking capital 
appreciation through investing in stocks of companies in the health-
sciences industries. She has had recent success with investments in the 
pharmaceutical, managed-care, and biotechnology sectors. In the report 
that follows, Joanne discusses first-half performance and looks at 
prospects for the remainder of the fiscal year.

Respectfully yours, 

/s/ George Putnam

George Putnam
Chairman of the Trustees
April 17, 1996



Report from the Fund Manager

Joanne Soja

Health-care stocks continued their run of strong performance throughout 
the six months ended February 29, 1996. Putnam Health Sciences Trust was 
once again a standout. Indeed, the fund's double-digit total returns for 
its class A and class B shares at net asset value, 26.93% and 26.49%, 
respectively (19.63% for class A shares at POP), handily surpassed both 
the Dow Jones Industrial Average (20.43%) and the Standard & Poor's 
500(registered trademark) Index (15.32%) for the period.

Your fund's outperformance continues to demonstrate the effectiveness of 
its flexible investment strategy. Although focused on the health-care 
sector, it emphasizes diversification across a variety of subsectors and 
investment in the stocks of companies at different levels of market 
capitalization. During the semiannual period, the fund benefited from 
strong performance in each of several key subsectors in which it 
invests: pharmaceuticals, medical equipment and supplies, managed care, 
biotechnology, and hospitals and providers.  

In addition, several small-company stocks held in the portfolio did 
particularly well in recent months. One such stock is Quintiles, a 
clinical research organization that helps pharmaceutical and 
biotechnology companies design and test emerging drug therapies more 
efficiently. Quintiles' stock, purchased very inexpensively last year, 
has increased in value by over 50% so far in 1996. Because it continues 
to exceed our earnings estimates, we increased the Quintiles position 
and it is now more than 1% of the fund's net assets. While this stock, 
along with others discussed in this report, was viewed favorably at the 
end of the period, all portfolio holdings are, of course, subject to 
review and adjustment in accordance with the fund's investment strategy 
and may well vary in the future.

Another winning issue in the portfolio was Biochem Pharmaceutical, a 
midsize biotechnology company that recently secured federal approval for 
producing a promising new AIDS drug. The value of Biochem's stock, up 
more than 200% in 1995, has already risen another 20% in 1996. 

The following discussion summarizes the fund's strategies during the 
period and offers insights into what we believe may lie ahead. 

*MANAGED-CARE STOCK SELECTION STRATEGY STAYS
ON TARGET

In the opening months of the period, we continued to observe a lack of 
investor interest in managed-care stocks, particularly those of health 
maintenance organizations (HMOs). Additionally, concern over proposed 
changes in Medicare and Medicaid spending threatened the performance of 
the entire medical-services sector. We chose to retain the fund's 
medical-services position but shifted assets into companies we felt 
confident had the potential to prosper despite a challenging market 
environment. 

Our selection strategy has proved successful thus far in fiscal 1996. 
For example, among the fund's HMO holdings, we took some profits in 
Humana and U.S. Healthcare, reducing their positions in the portfolio, 
and shifted the assets into Pacificare and Oxford Healthcare. 
Pacificare, with its proven establishment of Medicare HMOs and lower 
margin risk, continues to be a strong performer for the fund. More 
recently, we began a position in Oxford Healthcare at a bargain price 
and have since seen a rapid increase in the value of the shares. 

[GRAPHIC OMITTED:  horizontal bar chart TOP INDUSTRY SECTORS *]
showing:

Pharmaceuticals                       35.4%
Medical equipment and supplies        15.8%
Managed care                          12.0%
Medical devices                       11.6%
Biotechnology                         7.2%

Footnote reads:
*Based on net assets as of 2/29/96. Holdings will vary over time.

Considering the need for quality health-care delivery at affordable 
costs, we believe interest in HMOs will continue in the future. In fact, 
most HMO enrollments are still growing at double-digit rates. We are 
confident that our strict selection criteria for managed-care stocks -- 
which emphasize those with strong enrollment gains or with a good handle 
on their cost structures -- will be a distinguishing factor in fund 
performance this year.


*PRODUCT-ORIENTED STOCKS BOOST PERFORMANCE IN THE PHARMACEUTICAL 
SUBSECTOR


Pharmaceutical companies, as a group, have had a spectacular run over 
the last few months and were up approximately 60% in 1995. In general, 
their rising valuations were balanced by strong corporate fundamentals 
and improved multiples. However, in our opinion, the real strength of 
this subsector lies in the potential created by new-product 
developments. Here are some examples from the portfolio:

Astra AB. Over the past 20 years, the Swedish drug company Astra has 
moved from relative obscurity to become one of the world's leading 
pharmaceutical companies. Its exceptional research and development 
efforts have led to the creation of leading products in the 
gastrointestinal and respiratory categories, among others. It was Astra 
researchers who were among those who recognized that a bacterium, H. 
pylori, not stress and gastric acid as was previously thought, is a 
primary cause of stomach ulcers. Astra's anti-ulcer agent, Losec 
(Prilosec in the United States), is now beginning to replace other ulcer 
treatments worldwide. Astra is also a world leader in asthma therapy 
with its drug Pulmicort and unique Turbuhaler, a breath-actuated 
delivery system for inhaled steroids. This system is currently 
undergoing review by the Food and Drug Administration in order to be 
approved for use in the United States. Astra is an example of a rapidly 
growing overseas company that is presently selling at slightly lower 
multiples than many domestic companies. We have increased the 
portfolio's Astra position to approximately 1% of the fund's net assets. 
Because your fund may invest up to 20% of its assets in foreign 
securities, we will seek to seize attractive opportunities such as this 
one whenever possible. 

[GRAPHIC OMITTED:  TOP 10 HOLDINGS (2/29/96)
showing:

Johnson & Johnson
Medical equipment and supplies

Merck & Co., Inc.
Pharmaceuticals

Abbott Laboratories
Medical equipment and supplies

SmithKline Beecham PLC ADR (United Kingdom)
Pharmaceuticals

Eli Lilly & Co.
Phamaceuticals

Pfizer, Inc.
Pharmaceuticals

United Healthcare Corp.
Managed care

Medtronic, Inc.
Medical equipment and supplies

Schering-Plough Corp.
Pharmaceuticals

American Home Products Corp.
Pharmaceuticals

Footnote reads: These holdings represent 43.2% of the fund's net
assets. Portfolio holdings will vary over time.

Eli Lilly & Company. This major pharmaceutical company, currently 
representing approximately 4.4% of net assets, continues to contribute 
significantly to overall fund performance. Lilly is focused on the 
development of an important new drug in the treatment of schizophrenia. 

SmithKline Beecham. Another large-cap drug company, SmithKline, has 
several new pharmaceutical products in the pipeline. In recent clinical 
trials, Coreg, a new heart-disease drug, demonstrated dramatic 
improvement in the subjects who received it. 

We believe that each of these companies will continue to enjoy a 
combination of top-line sales growth and high earnings. Thus, they 
appear to be innovative and dynamic performers for the fund.


*NEW OPPORTUNITIES ABOUND IN MEASURING THE QUALITY OF HEALTH CARE

We see new themes currently emerging in health care. An extended period 
of self-reform throughout the industry has given rise to several new 
opportunities to measure the quality of care and to prevent disease. A 
wealth of new products combined with efforts to manage health-care 
delivery demands that consumers and payers be given tools by which to 
evaluate the appropriateness of care. For example, many HMOs have 
developed software bases that evaluate doctors for both inadequate care 
and overprescription of care. Another area is the provision of 
information through computer services that more effectively link 
communications between physicians and hospitals. 

Another area receiving an increasing focus is women's health care. More 
dollars than ever before are being spent. Neuromedical Systems, a 
portfolio company within the medical supplies and devices subsector, has 
developed an improved scan process for Pap smears, which are essential 
in the early detection of cervical cancer. While it may add to the 
initial cost of a test, the enhanced Pap smear imaging should more than 
compensate in total dollars for the prevention of more costly cancers. 
Also, Conceptus, Inc., a recent addition to the portfolio, is in the 
early stages of developing innovative answers to such needs as 
infertility. American Home Products Corp., one of the fund's 
pharmaceutical companies, recently produced an improved combination 
therapy of estrogen-progesterone that is superior to estrogen 
replacement alone for many female patients. And Merck has joined forces 
with American Home Products to market a new product for the ob-gyn 
market that combats osteoporosis. 

One of your fund's goals is to give your investment the potential to 
benefit from successful cutting-edge approaches to products and services 
wherever they are found: from smaller companies as well as from the 
tried-and-true larger companies.

*OUTLOOK: CAUTIOUS OPTIMISM GOING FORWARD

Quite naturally, we are very pleased with your fund's semiannual 
results. At the same time, we must caution that strong market 
performance like this does not last indefinitely. It would be realistic 
to expect some moderation to come in the pace of the market's advance.

Over the short- to intermediate-term, health-care stocks may depend on 
several factors including their earnings relative to the market. And we 
are somewhat concerned about rising stock prices across the health-care 
industry due to the current environment of intensive investment. 
However, we believe our bottom-up approach to growth stock selection -- 
continuing to seek out companies with strong earnings potential within 
diverse health-care subsectors -- should continue to move your fund 
favorably forward in 1996, though possibly at a more subdued pace than 
in 1995.

The views expressed here are exclusively those of Putnam Management.  
They are not meant as investment advice.  Although the described 
holdings were viewed favorably as of 2/29/96, there is no guarantee the 
fund will continue to hold these securities in the future.



Performance summary

Performance should always be considered in light of a fund's investment 
strategy.  Putnam Health Sciences Trust is designed for investors 
seeking capital appreciation through investments in the health sciences 
industries.

This section provides, at a glance, information about your fund's 
performance. Total return  shows how the value of the fund's shares 
changed over time, assuming you held the shares through the entire 
period and reinvested all distributions in the fund.


TOTAL RETURN FOR PERIODS ENDED 2/29/96
  
                      Class A             Class B          Class M
Inception date         4/8/82             3/1/93           7/3/95
                    NAV      POP       NAV     CDSC     NAV      POP
- ---------------------------------------------------------------------
6 months           26.93%   19.63%   26.49%   21.49%   26.63%   22.21%
- ---------------------------------------------------------------------
1 year             44.57    36.26    43.48    38.48       --       --
- ---------------------------------------------------------------------
5 years           105.48    93.66       --       --       --       --
Annual average     15.49    14.13       --       --       --       --
- ---------------------------------------------------------------------
10 years          399.37   370.56       --       --       --       --
Annual average     17.45    16.75       --       --       --       --
- ---------------------------------------------------------------------
Life of class         --       --    93.92    90.92    34.87    30.16
Annual average        --       --    24.70    24.06       --       --
 --------------------------------------------------------------------

COMPARATIVE INDEX RETURNS FOR PERIODS ENDED 2/29/96
                                   
                            Standard & Poor's
                                 500
                             (registered            Consumer Price
                            trademark) Index                Index
- ------------------------------------------------------------------
6 months                          15.32%                      1.31%
- ------------------------------------------------------------------
1 year                            34.66                       2.65
- ------------------------------------------------------------------
5 years                          101.10                      14.91
Annual average                    15.00                       2.82
- ------------------------------------------------------------------
10 years                         285.67                      41.72
Annual average                    14.45                       3.55
- ------------------------------------------------------------------
Life of class B                   56.63                       8.25
Annual average                    16.13                       2.68
- ------------------------------------------------------------------
Life of class M                   18.95                       1.57
- ------------------------------------------------------------------

Performance data represent past results, do not reflect future 
performance, and will differ for each share class. They do not take into 
account any adjustment for taxes payable on reinvested distributions or, 
for class A shares, distribution fees prior to implementation of the 
class A distribution plan in 1990.  Investment returns and net asset 
value will fluctuate so that an investor's shares, when sold, may be 
worth more or less than their original cost.  POP assumes 5.75% maximum 
sales charge for class A shares and 3.50% for class M shares. CDSC for 
class B shares assumes the applicable contingent deferred sales charge, 
with the maximum being 5%.



TOTAL RETURN FOR PERIODS ENDED 3/31/96
(most recent calendar quarter)

                     Class A            Class B             Class M
Inception dates      4/8/82              3/1/93              7/3/95
                  NAV      POP       NAV       CDSC       NAV      POP
- -----------------------------------------------------------------------
6 months        18.12%    11.34%    17.71%    12.71%    17.81%    13.69%
- -----------------------------------------------------------------------
1 year          40.21     32.14     39.14     34.14        --        --
- -----------------------------------------------------------------------
5 years         94.32     83.12        --        --        --        --
Annual average  14.21     12.86        --        --        --        --
- -----------------------------------------------------------------------
10 years       352.34    326.41        --        --        --        --
Annual average  16.29     15.61        --        --        --        --
- -----------------------------------------------------------------------
Life of class      --        --     93.79     90.79      34.81    30.10
Annual average     --        --     23.88     23.25         --       --
- -----------------------------------------------------------------------

Performance data represent past results, do not reflect future 
performance, and will differ for each share class. They do not take into 
account any adjustment for taxes payable on reinvested distributions or, 
for class A shares, distribution fees prior to implementation of the 
class A distribution plan in 1990. Investment returns and net asset 
value will fluctuate so that an investor's shares, when sold, may be 
worth more or less than their original cost.


PRICE AND DISTRIBUTION INFORMATION
6 months ended 2/29/96  

                           Class A       Class B       Class M
- ------------------------------------------------------------------------
Distributions (number)                                                  
- ------------------------------------------------------------------------
Number                          1             1               1
- ------------------------------------------------------------------------
Income                      $0.27         $0.08          $0.145
- ------------------------------------------------------------------------
Capital gains                                                           
- ------------------------------------------------------------------------
Long-term                   0.909         0.909           0.909
- ------------------------------------------------------------------------
Short-term                  0.013         0.013           0.013
- ------------------------------------------------------------------------
     Total                 $1.192        $1.002          $1.067
- ------------------------------------------------------------------------
Share value:         NAV       POP         NAV       NAV       POP
- ------------------------------------------------------------------------
8/31/95            $36.21     $38.42     $35.72    $36.17     $37.48
- ------------------------------------------------------------------------
2/29/96             44.66      47.38      44.09     44.64      46.26
- ------------------------------------------------------------------------


TERMS AND DEFINITIONS 


Class A shares are generally subject to an initial sales charge.  

Class B shares may be subject to a sales charge upon redemption.

Class M shares have a lower initial sales charge and a higher 12b-1 fee 
than class A shares and no sales charge on redemption. 

Net asset value (NAV) is the value of all your fund's assets, minus any 
liabilities, divided by the number of outstanding shares, not including 
any initial or contingent deferred sales charge. 

Public offering price (POP)  is the price of a mutual fund share plus 
the  maximum sales charge levied at the time of purchase. POP 
performance figures shown here assume the maximum 5.75% sales charge for 
class A shares and 3.50% for class M shares.

Contingent deferred sales charge (CDSC) is a charge applied at the time 
of the redemption of class B shares and assumes redemption at the end of 
the period. Your fund's CDSC declines from a 5% maximum during the first 
year to 1% during the sixth year. After the sixth year, the CDSC no 
longer applies.


COMPARATIVE BENCHMARKS


Standard & Poor's 500(registered trademark) Index is an unmanaged list 
of common stocks that is frequently used as a general measure of stock 
market performance.

Dow Jones Industrial Average (DJIA) is an unmanaged list of 30 common 
stocks frequently used as a general measure of stock market performance.

Consumer Price Index (CPI) is a commonly used measure of inflation; it 
does not represent an investment return.


These indexes assume reinvestment of all distributions and do not take 
into account brokerage commissions or other costs. The fund's portfolio 
contains securities that do not match those in the indexes and 
performance will differ. It is not possible to invest in an index.



<TABLE>
<CAPTION>

Portfolio of investments owned
February 29, 1996 (Unaudited)

COMMON STOCKS  (92.9%)*
NUMBER OF SHARES                                                                               VALUE
- ----------------------------------------------------------------------------------------------------
<S>            <C>       <C>                                                            <C>
Biotechnology  (7.2%)
- ----------------------------------------------------------------------------------------------------
                500,000  Amgen, Inc. +                                                   $29,875,000
                306,500  Amylin Pharmaceuticals, Inc. +                                    3,448,125
                350,000  Athena Neurosciences, Inc. +                                      4,900,000
                250,000  Biochem Pharmaceutical, Inc. +                                   11,562,500
                150,000  Biogen, Inc. +                                                    9,806,250
                120,000  Cor Therapeutics Inc. +                                           1,252,500
                200,000  CytoTherapeutics, Inc. +                                          2,950,000
                100,000  Ergo Science Corp. +                                              2,200,000
                212,500  Genentech, Inc. +                                                11,607,813
                150,000  Genome Therapeutics Corp. +                                       2,006,250
                100,000  Immulogic Pharmaceutical Corp. +                                  1,975,000
                200,000  La Jolla Pharmaceutical Co. +                                     1,437,500
                120,000  Ligand Pharmaceuticals, Inc. Class B +                            1,455,000
                100,000  Magainin Pharmaceuticals, Inc. +                                  1,287,500
                197,200  Martek Biosciences Corp. +                                        6,556,900
                 80,000  Medimmune, Inc. +                                                 1,500,000
                190,000  Metra Biosystems, Inc. +                                          2,850,000
                 35,000  Myriad Genetics, Inc. +                                           1,006,250
                 60,000  NPS Pharmaceuticals, Inc. +                                         870,000
                 50,000  Synaptic Pharmaceutical Corp. +                                     875,000
                133,400  Vertex Pharmaceuticals, Inc. +                                    3,701,850
                                                                                      --------------
                                                                                         103,123,438
Clinics & Hospitals  (2.8%)
- ----------------------------------------------------------------------------------------------------
                200,000  Columbia/HCA Healthcare Corp.                                    10,950,000
                 23,900  National Surgery Centers, Inc. +                                    663,225
                210,000  Quantum Health Resources, Inc. +                                  2,257,500
                213,900  Quorum Health Group, Inc. +                                       5,267,288
                 48,000  Renal Care Group, Inc. +                                          1,320,000
                223,100  Tenet Healthcare Corp. +                                          4,991,860
                 30,000  Total Renal Care Holdings, Inc. +                                   885,000
                480,000  Vivra, Inc. +                                                    14,160,000
                                                                                      --------------
                                                                                          40,494,873
Distribution/Retail  (1.5%)
- ----------------------------------------------------------------------------------------------------
                102,000  Amerisource Health Corp. Class A +                                2,958,000
                 50,900  Cardinal Health, Inc.                                             3,066,725
                160,900  Eckerd Corp. +                                                    7,220,388
                665,000  Owens & Minor, Inc.                                               7,730,625
                                                                                      --------------
                                                                                          20,975,738
Drugs  (35.4%)
- ----------------------------------------------------------------------------------------------------
                360,000  Allergan Inc.                                                   $13,410,000
                210,000  Alza Corp. +                                                      6,982,500
                380,000  American Home Products Corp.                                     37,430,000
                268,000  Astra AB (Sweden)                                                12,290,850
                220,000  Bristol-Myers Squibb Co.                                         18,727,500
                  7,000  Ciba-Geigy AG (Switzerland)                                       6,242,298
                120,000  Elan Corp. PLC ADR (Ireland) +                                    6,960,000
                134,100  Forest Laboratories, Inc. Class A +                               6,973,200
                225,000  Ivax Corp.                                                        6,440,625
              1,040,000  Lilly (Eli) & Co.                                                62,920,000
              1,087,200  Merck & Co., Inc.                                                72,027,000
                230,000  Mylan Laboratories, Inc.                                          4,485,000
                945,000  Pfizer, Inc.                                                     62,251,875
                725,000  Pharmacia & Upjohn, Inc.                                         30,359,375
                120,000  R.P. Scherer Corp. +                                              5,280,000
                  7,000  Sandoz AG (Switzerland)                                           6,562,864
                690,000  Schering-Plough Corp.                                            38,726,250
              1,210,000  SmithKline Beecham PLC ADR (United Kingdom)                      66,247,500
                100,200  Synthelabo (France)                                               7,025,415
                330,000  Warner-Lambert Co.                                               32,628,750
                                                                                      --------------
                                                                                         503,971,002
Information Systems  (2.3%)
- ----------------------------------------------------------------------------------------------------
                 50,000  Enterprise Systems, Inc. +                                        1,312,500
                220,000  GMIS, Inc. +                                                      2,887,500
                 50,000  HCIA, Inc. +                                                      2,662,500
                125,575  Health Management Systems, Inc. +                                 3,673,069
                625,000  Physicians Computer Network +                                     8,671,875
                230,000  Shared Medical Systems Corp.                                     12,822,500
                 49,100  Summit Medical Systems, Inc. +                                      994,275
                                                                                      --------------
                                                                                          33,024,219
Managed Care  (12.0%)
- ----------------------------------------------------------------------------------------------------
                150,000  Coventry Corp. +                                                  2,662,500
                 75,000  Express Scripts, Inc. Class A +                                   4,106,250
                255,000  FHP Intl. Corp. +                                                 8,351,250
                120,000  Foundation Health Corp. +                                         4,680,000
                700,000  Humana Inc. +                                                    17,150,000
                360,000  Mid Atlantic Medical Services, Inc.                               7,605,000
                 54,500  Oxford Health Plans Inc. +                                        4,486,031
                271,000  Pacificare Health Systems, Inc. Class B +                        25,474,000
                100,000  Physicians Health Services, Inc. Class A +                        3,212,500
                208,200  Rightchoice Managed Care, Inc. Class A +                          3,383,250
                487,500  U.S. Healthcare Inc.                                             23,765,625
                880,000  United Healthcare Corp.                                          57,420,000
                305,900  Value Health, Inc. +                                              7,915,163
                                                                                      --------------
                                                                                         170,211,569
Medical Devices  (11.6%)
- ----------------------------------------------------------------------------------------------------
                155,000  Arrow International, Inc.                                        $6,316,250
                154,400  ArthoCare Corp. +                                                 3,474,000
                200,000  ATS Medical, Inc. +                                               2,125,000
                221,600  AVECOR Cardiovascular, Inc. +                                     2,936,200
                100,000  Biomet, Inc. +                                                    1,900,000
                340,145  Boston Scientific Corp. +                                        16,326,960
                170,000  Chad Therapeutics, Inc. +                                         2,061,250
                 36,700  Conceptus, Inc. +                                                   724,825
                106,000  Instent, Inc. +                                                   2,120,000
              1,000,000  Medtronic, Inc.                                                  57,375,000
                340,000  Mentor Corp.                                                      8,712,500
                150,000  Minimed, Inc. +                                                   2,475,000
                200,000  Orthologic Corp. +                                                5,325,000
                225,000  St. Jude Medical Inc. +                                           8,493,750
                468,000  Stryker Corp. +                                                  25,389,000
                100,000  Target Therapeutics, Inc. +                                       5,237,500
                340,000  U.S. Surgical Corp.                                               9,647,500
                220,000  Ventritex, Inc. +                                                 3,960,000
                                                                                      --------------
                                                                                         164,599,735
Medical Equipment and Supplies  (15.8%)
- ----------------------------------------------------------------------------------------------------
              1,590,000  Abbott Laboratories                                              66,382,500
                510,000  Bard (C.R.), Inc.                                                18,296,250
                463,750  Baxter International, Inc.                                       21,216,563
                310,000  Haemonetics Corp. +                                               5,270,000
                151,900  Heartstream, Inc. +                                               2,240,525
              1,005,182  Johnson & Johnson                                                93,984,517
                150,000  Molecular Devices Corp. +                                         1,856,250
                210,400  Nellcor Puritan Bennett, Inc. +                                  14,096,800
                 21,400  Neuromedical Systems, Inc. +                                        430,675
                 75,000  Rochester Medical Corp. +                                         1,087,500
                                                                                      --------------
                                                                                         224,861,580
Nursing Homes  (2.1%)
- ----------------------------------------------------------------------------------------------------
                100,700  ARV Assisted Living, Inc. +                                       1,762,250
                620,000  Beverly Enterprises Inc. +                                        7,517,500
                220,000  Health Care & Retirement Corp. +                                  8,937,500
                159,100  Horizon/CMS Healthcare Corp. +                                    3,778,625
                210,000  Manor Care, Inc.                                                  8,058,750
                                                                                      --------------
                                                                                          30,054,625
Other Health Care Services  (1.2%)
- ----------------------------------------------------------------------------------------------------
                 23,600  Pharmaceutical Product Development, Inc. +                          640,150
                250,200  Quintiles Transnational Corp. +                                  16,513,200
                                                                                      --------------
                                                                                          17,153,350
Physicians Group Management  (1.0%)
- ----------------------------------------------------------------------------------------------------
                300,000  Medaphis Corp. +                                                $11,662,500
                110,000  OccuSystems, Inc. +                                               2,158,750
                 56,100  Physician Support Systems, Inc. +                                   995,775
                                                                                      --------------
                                                                                          14,817,025
                                                                                      --------------
                         Total Common Stocks   (cost $683,840,814)                    $1,323,287,154
                                                                                      --------------
SHORT-TERM INVESTMENTS  (6.7%)*
PRINCIPAL AMOUNT                                                                               VALUE
- ----------------------------------------------------------------------------------------------------
            $25,000,000  American Telephone & Telegraph Capital Corp.,
                         effective yield of 5.2%, April 1, 1996                          $24,888,055
             11,063,000  Federal Home Loan Mortgage Corp., effective
                         yield of 5.48%, March 1, 1996                                    11,063,000
             59,278,000  Interest in $1,108,321,000 joint repurchase
                         agreement dated February 29, 1996 with
                         Morgan (J.P.) & Co. Inc., due March 1, 1996
                         with respect to various U.S. Treasury
                         obligations-maturity value of $59,286,925
                         for an effective yield of 5.42%                                  59,286,925
                                                                                      --------------
                         Total Short-Term Investments   (cost $95,237,980)               $95,237,980
                                                                                      --------------
                         Total Investments  (cost $779,078,794)***                    $1,418,525,134
- ----------------------------------------------------------------------------------------------------
*    Percentages indicated are based on net assets of $1,424,012,728. 
+    Non-income-producing security. 
***  The aggregate identified cost on a tax basis is $779,078,794 resulting in a gross unrealized 
     appreciation and depreciation of $677,279,802 and $37,833,462, respectively, or net unrealized 
     appreciation of $639,446,340. 

ADR after the name of a foreign holding stands for American Depository Receipt, representing ownership 
of foreign securities on deposit with a domestic custodian bank. 

The accompanying notes are an integral part of these financial statements.

</TABLE>



<TABLE>
<CAPTION>

Statement of assets and liabilities
February 29, 1996 (Unaudited)
- ------------------------------------------------------------------------------------
Assets
- ------------------------------------------------------------------------------------
<S>                                                                  <C>
Investments in securities, at value
(identified cost $779,078,794 ) (Note 1)                              $1,418,525,134
- ------------------------------------------------------------------------------------
Cash                                                                             211
- ------------------------------------------------------------------------------------
Dividends and interest receivable                                          1,535,828
- ------------------------------------------------------------------------------------
Receivable for shares of the fund sold                                    10,423,965
- ------------------------------------------------------------------------------------
Receivable for securities sold                                             3,685,064
- ------------------------------------------------------------------------------------
Total assets                                                           1,434,170,202

Liabilities
- ------------------------------------------------------------------------------------
Payable for securities purchased                                             746,022
- ------------------------------------------------------------------------------------
Payable for shares of the fund repurchased                                 6,137,250
- ------------------------------------------------------------------------------------
Payable for compensation of Manager (Note 2)                               2,062,582
- ------------------------------------------------------------------------------------
Payable for compensation of Trustees (Note 2)                                  1,350
- ------------------------------------------------------------------------------------
Payable for administrative services (Note 2)                                   4,260
- ------------------------------------------------------------------------------------
Payable for distribution fees (Note 2)                                       643,187
- ------------------------------------------------------------------------------------
Payable for investor servicing and custodian fees (Note 2)                   383,392
- ------------------------------------------------------------------------------------
Other accrued expenses                                                       179,431
- ------------------------------------------------------------------------------------
Total liabilities                                                         10,157,474
- ------------------------------------------------------------------------------------
Net assets                                                            $1,424,012,728

Represented by
- ------------------------------------------------------------------------------------
Paid-in-capital (Note 4)                                                $780,637,011
- ------------------------------------------------------------------------------------
Distributions in excess of net investment income                          (1,423,495)
- ------------------------------------------------------------------------------------
Accumulated net realized gain on investments                               5,352,872
- ------------------------------------------------------------------------------------
Net unrealized appreciation of investments                               639,446,340
- ------------------------------------------------------------------------------------
Total -- Representing net assets applicable to
capital shares outstanding                                            $1,424,012,728

Computation of net asset value and offering price
- ------------------------------------------------------------------------------------
Net asset value and redemption price of class A shares
($1,201,126,399 divided by 26,893,105 shares)                                 $44.66
- ------------------------------------------------------------------------------------
Offering price per class A share (100/94.25 of $44.66)*                       $47.38
- ------------------------------------------------------------------------------------
Net asset value and offering price of class B shares
($218,517,789 divided by 4,956,650 shares)**                                  $44.09
- ------------------------------------------------------------------------------------
Net asset value and redemption price of class M shares
($4,368,540 divided by 97,862 shares)                                         $44.64
- ------------------------------------------------------------------------------------
Offering price per class M share (100/96.50 of $44.64)*                       $46.26
- ------------------------------------------------------------------------------------
+  On single retail sales of less than $50,000. On sales of $50,000 or more and on group 
   sales the offering price is reduced.
++ Redemption price per share is equal to net asset value less any applicable contingent 
   deferred sales charge.

The accompanying notes are an integral part of these financial statements.

</TABLE>



<TABLE>
<CAPTION>

Statement of operations
Six months ended February 29, 1996 (Unaudited)
- -----------------------------------------------------------------------------------
<S>                                                                  <C>
Investment income:
- ------------------------------------------------------------------------------------
Dividends (net of foreign tax of $11,815)                                 $7,124,665
- ------------------------------------------------------------------------------------
Interest                                                                   1,586,644
- ------------------------------------------------------------------------------------
Total investment income                                                    8,711,309

Expenses:
- ------------------------------------------------------------------------------------
Compensation of Manager (Note 2)                                           3,871,528
- ------------------------------------------------------------------------------------
Investor servicing and custodian fees (Note 2)                               909,982
- ------------------------------------------------------------------------------------
Compensation of Trustees (Note 2)                                             16,478
- ------------------------------------------------------------------------------------
Administrative services (Note 2)                                              14,391
- ------------------------------------------------------------------------------------
Distribution fees -- Class A (Note 2)                                      1,339,268
- ------------------------------------------------------------------------------------
Distribution fees -- Class B (Note 2)                                        778,331
- ------------------------------------------------------------------------------------
Distribution fees -- Class M (Note 2)                                          7,106
- ------------------------------------------------------------------------------------
Auditing                                                                      20,118
- ------------------------------------------------------------------------------------
Legal                                                                         12,545
- ------------------------------------------------------------------------------------
Postage                                                                      103,277
- ------------------------------------------------------------------------------------
Reports to shareholders                                                       63,112
- ------------------------------------------------------------------------------------
Registration fees                                                             51,354
- ------------------------------------------------------------------------------------
Other                                                                         81,344
- ------------------------------------------------------------------------------------
Total expenses                                                             7,268,834
- ------------------------------------------------------------------------------------
Expense reduction (Note 2)                                                   (47,562)
- ------------------------------------------------------------------------------------
Net expenses                                                               7,221,272
- ------------------------------------------------------------------------------------
Net investment income                                                      1,490,037
- ------------------------------------------------------------------------------------
Net realized gain on investments (Notes 1 and 3)                           9,942,244
- ------------------------------------------------------------------------------------
Net unrealized appreciation of investments during the period             275,229,199
- ------------------------------------------------------------------------------------
Net gain on investments                                                  285,171,443
- ------------------------------------------------------------------------------------
Net increase in net assets resulting from operations                    $286,661,480
- ------------------------------------------------------------------------------------

The accompanying notes are an integral part of these financial statements.

</TABLE>



<TABLE>
<CAPTION>

Statement of changes in net assets
- --------------------------------------------------------------------------------------------------------
                                                                    Six months ended          Year ended
                                                                         February 29           August 31
                                                                                1996*               1995
- --------------------------------------------------------------------------------------------------------
<S>                                                                  <C>                  <C>
Increase in net assets
- --------------------------------------------------------------------------------------------------------
Operations:
- --------------------------------------------------------------------------------------------------------
Net investment income                                                     $1,490,037          $5,819,982
- --------------------------------------------------------------------------------------------------------
Net realized gain on investment transactions                               9,942,244          23,154,465
- --------------------------------------------------------------------------------------------------------
Net unrealized appreciation of investment transactions                   275,229,199         177,658,264
- --------------------------------------------------------------------------------------------------------
Net increase in net assets resulting from operations                     286,661,480         206,632,711
- --------------------------------------------------------------------------------------------------------
Distributions to shareholders
- --------------------------------------------------------------------------------------------------------
From net investment income:
   Class A                                                                (6,941,343)         (6,665,340)
- --------------------------------------------------------------------------------------------------------
   Class B                                                                  (304,825)           (276,702)
- --------------------------------------------------------------------------------------------------------
   Class M                                                                    (6,773)                 --
- --------------------------------------------------------------------------------------------------------
From net realized gain on investments:
   Class A                                                               (23,698,137)        (13,402,834)
- --------------------------------------------------------------------------------------------------------
   Class B                                                                (3,515,513)         (1,193,139)
- --------------------------------------------------------------------------------------------------------
   Class M                                                                   (43,065)                 --
- --------------------------------------------------------------------------------------------------------
Increase from capital share transactions (Note 4)                        128,726,667          13,017,671
- --------------------------------------------------------------------------------------------------------
Total increase in net assets                                             380,878,491         198,112,367
- --------------------------------------------------------------------------------------------------------
Net assets
- --------------------------------------------------------------------------------------------------------
Beginning of period                                                    1,043,134,237         845,021,870
- --------------------------------------------------------------------------------------------------------
End of period (including distributions in excess of
   net investment income of $1,423,495 and undistributed
   net investment income of $4,339,409, respectively)                 $1,424,012,728      $1,043,134,237
- --------------------------------------------------------------------------------------------------------

+Unaudited.

The accompanying notes are an integral part of these financial statements.

</TABLE>



<TABLE>
<CAPTION>

Financial highlights
(For a share outstanding throughout the period)
- ------------------------------------------------------------------------------------------------
                                                       July 3, 1995                
                                        Six months    (commencement     Six months        
                                             ended    of operations)         ended    Year ended
                                       February 29        August 31    February 29     August 31
- ------------------------------------------------------------------------------------------------
                                              1996*+           1995           1996*+        1995
- ------------------------------------------------------------------------------------------------
                                                     Class M                             Class B
- ------------------------------------------------------------------------------------------------
<S>                                         <C>             <C>            <C>           <C>
Net asset value,
beginning of period                         $36.17           $33.96         $35.72        $29.47
- ------------------------------------------------------------------------------------------------
Investment operations
- ------------------------------------------------------------------------------------------------
Net investment income (loss)                  (.03)            (.02)          (.08)          .11
- ------------------------------------------------------------------------------------------------
Net realized and unrealized
gain (loss) on investments                    9.57             2.23           9.45          6.78
- ------------------------------------------------------------------------------------------------
Total from investment
operations                                    9.54             2.21           9.37          6.89
- ------------------------------------------------------------------------------------------------
Less distributions:
- ------------------------------------------------------------------------------------------------
From net investment income                    (.15)              --           (.08)         (.12)
- ------------------------------------------------------------------------------------------------
From net realized gain
on investments                                (.92)              --           (.92)         (.52)
- ------------------------------------------------------------------------------------------------
Total distributions                          (1.07)              --          (1.00)         (.64)
- ------------------------------------------------------------------------------------------------
Net asset value, end of period              $44.64           $36.17         $44.09        $35.72
- ------------------------------------------------------------------------------------------------
Total investment return at
net asset value  (%) (a)                     26.63(b)          6.51(b)       26.49(b)      23.83
- ------------------------------------------------------------------------------------------------
Net assets, end of period
(in thousands)                              $4,369             $321       $218,518      $113,329
- ------------------------------------------------------------------------------------------------
Ratio of expenses to average
net assets (%) (c)                             .78(b)           .30(b)         .91(b)       1.88
- ------------------------------------------------------------------------------------------------
Ratio of net investment income
to average net assets (%)                     (.07)(b)         (.02)(b)       (.20)(b)      (.05)
- ------------------------------------------------------------------------------------------------
Portfolio turnover (%)                        2.95(b)         19.51           2.95(b)      19.51
- ------------------------------------------------------------------------------------------------



<CAPTION>

Financial highlights (Continued)
(For a share outstanding throughout the period)
- ------------------------------------------------------------------------------------------------
                                                      March 1, 1993                
                                                      (commencement      Six months        
                                        Year ended    of operations)          ended
                                         August 31        August 31     February 29
- ------------------------------------------------------------------------------------------------
                                              1994             1993+           1996*+       1995
- ------------------------------------------------------------------------------------------------
                                                              Class B
- ------------------------------------------------------------------------------------------------
<S>                                         <C>             <C>            <C>           <C>
Net asset value,
beginning of period                         $24.28           $24.02          $36.21       $29.77
- ------------------------------------------------------------------------------------------------
Investment operations
- ------------------------------------------------------------------------------------------------
Net investment income (loss)                   .10              .05             .07          .23
- ------------------------------------------------------------------------------------------------
Net realized and unrealized
gain (loss) on investments                    5.33              .21            9.57         6.99
- ------------------------------------------------------------------------------------------------
Total from investment
operations                                    5.43              .26            9.64         7.22
- ------------------------------------------------------------------------------------------------
Less distributions:
- ------------------------------------------------------------------------------------------------
From net investment income                    (.19)              --            (.27)        (.26)
- ------------------------------------------------------------------------------------------------
From net realized gain
on investments                                (.05)              --            (.92)        (.52)
- ------------------------------------------------------------------------------------------------
Total distributions                           (.24)              --           (1.19)        (.78)
- ------------------------------------------------------------------------------------------------
Net asset value, end of period              $29.47           $24.28          $44.66       $36.21
- ------------------------------------------------------------------------------------------------
Total investment return at
net asset value  (%) (a)                     22.49            (1.08)(b)       26.93(b)     24.81
- ------------------------------------------------------------------------------------------------
Net assets, end of period
(in thousands)                             $55,424          $18,455      $1,201,126     $929,484
- ------------------------------------------------------------------------------------------------
Ratio of expenses to average
net assets (%) (c)                            1.87              .96(b)          .54(b)      1.12
- ------------------------------------------------------------------------------------------------
Ratio of net investment income
to average net assets (%)                      .24              .21(b)          .17(b)       .70
- ------------------------------------------------------------------------------------------------
Portfolio turnover (%)                       23.18            45.46            2.95(b)     19.51
- ------------------------------------------------------------------------------------------------



<CAPTION>

Financial highlights (Continued)
(For a share outstanding throughout the period)
- ------------------------------------------------------------------------------------------------
                                                    Year ended August 31    
- ------------------------------------------------------------------------------------------------
                                              1994              1993          1992          1991
- ------------------------------------------------------------------------------------------------
                                                      Class A
- ------------------------------------------------------------------------------------------------
<S>                                        <C>              <C>            <C>           <C>
Net asset value,
beginning of period                         $24.40            $28.31        $31.29        $22.82
- ------------------------------------------------------------------------------------------------
Investment operations
- ------------------------------------------------------------------------------------------------
Net investment income (loss)                   .30               .26           .12           .25
- ------------------------------------------------------------------------------------------------
Net realized and unrealized
gain (loss) on investments                    5.36             (1.82)         (.35)         9.07
- ------------------------------------------------------------------------------------------------
Total from investment
operations                                    5.66             (1.56)         (.23)         9.32
- ------------------------------------------------------------------------------------------------
Less distributions:
- ------------------------------------------------------------------------------------------------
From net investment income                    (.24)             (.13)         (.27)         (.35)
- ------------------------------------------------------------------------------------------------
From net realized gain
on investments                                (.05)            (2.22)        (2.48)         (.50)
- ------------------------------------------------------------------------------------------------
Total distributions                           (.29)            (2.35)        (2.75)         (.85)
- ------------------------------------------------------------------------------------------------
Net asset value, end of period              $29.77            $24.40        $28.31        $31.29
- ------------------------------------------------------------------------------------------------
Total investment return at
net asset value  (%) (a)                     23.38             (6.45)        (1.12)        41.99
- ------------------------------------------------------------------------------------------------
Net assets, end of period
(in thousands)                            $789,598          $764,443      $970,412      $676,081
- ------------------------------------------------------------------------------------------------
Ratio of expenses to average
net assets (%) (c)                            1.12              1.13          1.20          1.18
- ------------------------------------------------------------------------------------------------
Ratio of net investment income
to average net assets (%)                      .96               .91           .61          1.27
- ------------------------------------------------------------------------------------------------
Portfolio turnover (%)                       23.18             45.46         42.12         26.59
- ------------------------------------------------------------------------------------------------

*   Unaudited.
+   Per share net investment income has been determined on the basis of weighted average number of 
    shares outstanding during the period.
(a) Total investment return assumes dividend reinvestment and does not reflect the effect of sales 
    charges.
(b) Not annualized.
(c) The ratio of expenses to average net assets for the period ended February 29, 1996 include amounts 
    paid through expense offset arrangements. Prior period ratios exclude these amounts. (Note 2)

</TABLE>



Notes to financial statements
February 29, 1996 (Unaudited)

Note 1 
Significant accounting policies

The fund is registered under the Investment Company Act of 1940, as 
amended, as a diversified, open-end management investment company. The 
investment objective of the fund is to seek capital appreciation by 
investing primarily in the common stocks of companies in the health 
sciences industries.

The fund offers class A, class B and class M shares.  Class A shares are 
sold with a maximum front-end sales charge of 5.75%. Class B shares, 
which convert to class A shares after approximately eight years, do not 
pay a front-end sales charge, but pay a higher ongoing distribution fee 
than class A shares, and are subject to a contingent deferred sales 
charge, if those shares are redeemed within six years of purchase. Class 
M shares are sold with a maximum front-end sales charge of 3.50% and pay 
an ongoing distribution fee that is lower than class B shares and higher 
than class A shares.

Expenses of the fund are borne pro-rata by the holders of each class of 
shares, except that each class bears expenses unique to that class 
(including the distribution fees applicable to such class). Each class 
votes as a class only with respect to its own distribution plan or other 
matters on which a class vote is required by law or determined by the 
Trustees. Shares of each class would receive their pro-rata share of the 
net assets of the fund, if the fund were liquidated. In addition, the 
Trustees declare separate dividends on each class of shares.

The following is a summary of significant accounting policies 
consistently followed by the fund in the preparation of its financial 
statements. The preparation of financial statements is in conformity 
with generally accepted accounting principles and requires management to 
make estimates and assumptions that affect the reported amounts of 
assets and liabilities. Actual results could differ from those 
estimates.

A) Security valuation Investments for which market quotations are 
readily available are stated at market value, which is determined using 
the last reported sale price, or, if no sales are reported -- as in the 
case of some securities traded over-the-counter -- the last reported bid 
price. Short-term investments having remaining maturities of 60 days or 
less are stated at amortized cost, which approximates market value, and 
other investments are stated at fair value following procedures approved 
by the Trustees. Foreign securities quoted in foreign currencies are 
translated into U.S. dollars at the current exchange rate. The fair 
value of restricted securities is determined by  Putnam Investment 
Management, Inc. ("Putnam Management"), the fund's manager, a wholly-
owned subsidiary of Putnam Investments, Inc., following procedures 
approved by the Trustees, and such valuations and procedures are 
reviewed periodically by the Trustees.

B) Joint trading account Pursuant to an exemptive order issued by the 
Securities and Exchange Commission, the fund may transfer uninvested 
cash balances into a joint trading account, along with the cash of other 
registered investment companies managed by Putnam Management and certain 
other accounts. These balances may be invested in one or more repurchase 
agreements and/or short-term money market instruments.

C) Repurchase agreements The fund or any joint trading account, through 
its custodian, receives delivery of the underlying securities, the 
market value of which at the time of purchase is required to be in an 
amount at least equal to 102% of the resale price, including accrued 
interest. Putnam Management is responsible for determining that the 
value of these underlying securities is at all times at least equal to 
102% of the resale price, including accrued interest.

D) Security transactions and related investment income Security 
transactions are accounted for on the trade date (date the order to buy 
or sell is executed). Interest income is recorded on the accrual basis 
and dividend income is recorded on the ex-dividend date, except that 
certain dividends from foreign securities are recorded as soon as the 
fund is informed of the ex-dividend date.

E) Federal taxes It is the policy of the fund to distribute all of its 
taxable income within the prescribed time and otherwise comply with the 
provisions of the Internal Revenue Code applicable to regulated 
investment companies. It is also the intention of the fund to distribute 
an amount sufficient to avoid imposition of any excise tax under Section 
4982 of the Internal Revenue Code of 1986. Therefore, no provision has 
been made for federal taxes on income, capital gains or unrealized 
appreciation of securities held and excise tax on income and capital 
gains.

F) Distributions to shareholders Distributions to shareholders are 
recorded by the fund on the ex-dividend date. Capital gain 
distributions, if any, are recorded on ex-dividend date and are paid at 
least annually. 

The amount and character of income and gains to be distributed are 
determined in accordance with income tax regulations which may differ 
from generally accepted accounting principles.

Note 2 
Management fee, administrative services, and other transactions

Compensation of Putnam Management, for management and investment 
advisory services is paid quarterly based on the average net assets of 
the fund for the quarter. Such fee is based on the following annual 
rates: 0.70% of the first $500 million of average net assets, 0.60% of 
the next $500 million, 0.55% of the next $500 million, and 0.50% of any 
excess over $1.5 billion, subject, under current law, to reduction in 
any year to the extent that expenses (exclusive of distribution fees, 
brokerage, interest and taxes) of the fund exceed 2.5% of the first $30 
million of average net assets, 2% of the next $70 million and 1.5% of 
any excess over $100 million and by the amount of certain brokerage 
commissions and fees (less expenses) received by affiliates of Putnam 
Management on the fund's portfolio transactions.

The fund reimburses  Putnam Management for the compensation and related 
expenses of certain officers of the fund and their staff who provide 
administrative services to the fund. The aggregate amount of all such 
reimbursements is determined annually by the Trustees.

Trustees of the fund receive an annual Trustee's fee of $2,540 and an 
additional fee for each Trustees' meeting attended. Trustees who are not 
interested persons of Putnam  Management and who serve on committees of 
the Trustees receive additional fees for attendance at certain committee 
meetings.

The fund adopted a Trustee Fee Deferral Plan (the "Plan") which allows 
the Trustees to defer the receipt of all or a portion of Trustees fees 
payable on or after July 1, 1995.  The deferred fees remain in the fund 
and are invested in the fund or in other Putnam funds until distribution 
in accordance with the Plan.

Custodial functions for the fund's assets are provided by Putnam 
Fiduciary Trust Company (PFTC), a wholly-owned subsidiary of Putnam 
Investments, Inc. Investor servicing agent functions are provided by 
Putnam Investor Services, a division of PFTC.

The fund has adopted distribution plans (the "Plans") with respect to 
its class A, class B and class M shares pursuant to Rule 12b-1 under the 
Investment Company Act of 1940.  The purpose of the Plans is to 
compensate Putnam Mutual Funds Corp., a wholly-owned subsidiary of 
Putnam Investments, Inc., for services provided and expenses incurred by 
it in distributing shares of the fund.  The Plans provide for payments 
by the fund to Putnam Mutual Funds Corp. at an annual rate of  to 0.35%, 
1.00% and 1.00% of average net assets attributable to class A, class B, 
and class M shares, respectively.  The Trustees have approved payment by 
the fund at an annual rate of 0.25%, 1.00%, and 0.75% of the average net 
assets attributable to class A, class B, and class M shares, 
respectively.

For the six months ended February 29, 1996, fund expenses were reduced 
by $47,562 under expense offset arrangements with PFTC  and brokerage 
service arrangements.  Investor servicing and custodian fees reported in 
the Statement of operations exclude these credits.  The fund could have 
invested the assets utilized in connection with the expense offset 
arrangements in an income producing asset if it had not entered into 
such arrangements.

For the six months ended February 29, 1996, Putnam Mutual Funds Corp., 
acting as underwriter received net commissions of $362,239 and $10,620 
from the sale of class A and class M shares, respectively. There was 
$200,302 in contingent deferred sales charges from redemptions of class 
B shares.  A deferred sales charge of up to 1% is assessed on certain 
redemptions of class A shares. For the six months ended February 29, 
1996, Putnam Mutual Funds Corp., acting as underwriter received $1,611 
on class A redemptions.

Note 3 
Purchases and sales of securities

During the six months ended February 29, 1996, purchases and sales of 
investment securities other than short-term investments aggregated 
$72,451,876 and $34,761,120, respectively. There were no purchases or 
sales of U.S. government obligations during the period. In determining 
the net gain or loss on securities sold, the cost of securities has been 
determined on the identified cost basis.

Note 4 
Capital shares

At February 29, 1996, there was an unlimited number of shares of 
beneficial interest authorized. Transactions in capital shares were as 
follows:
                            Six months ended 
                            February 29, 1996 
- ----------------------------------------------------
Class A                     Shares         Amount
- ----------------------------------------------------
Shares sold               6,579,426     $273,350,087
- ----------------------------------------------------
Shares issued in 
connection with 
reinvestment of 
distributions               595,522       24,386,722
- ----------------------------------------------------
                          7,174,948      297,736,809

Shares 
repurchased              (5,952,000)    (246,735,273)
- ----------------------------------------------------
Net increase              1,222,948      $51,001,536
- ----------------------------------------------------
                                 Year ended 
                              August 31, 1995
- ----------------------------------------------------
Class A                     Shares         Amount
- ----------------------------------------------------
Shares sold               8,052,125     $258,073,342
- ----------------------------------------------------
Shares issued in 
connection with 
reinvestment of 
distributions               535,035       15,853,096
- ----------------------------------------------------
                          8,587,160      273,926,438

Shares 
repurchased              (9,437,527)    (302,016,572)
- ----------------------------------------------------
Net decrease               (850,367)    $(28,090,134)
- ----------------------------------------------------
                               Six months ended 
                              February 29, 1996
- ----------------------------------------------------
Class B                     Shares         Amount
- ----------------------------------------------------
Shares sold               2,544,016     $111,990,528
- ----------------------------------------------------
Shares issued in 
connection with 
reinvestment of 
distributions               253,367        3,123,352
- ----------------------------------------------------
                          2,797,383      115,113,880

Shares 
repurchased              (1,013,550)     (41,086,070)
- ----------------------------------------------------
Net increase              1,783,833      $74,027,810
- ----------------------------------------------------

                                 Year ended 
                               August 31, 1995
- ----------------------------------------------------
Class B                     Shares         Amount
- ----------------------------------------------------
Shares sold               2,716,923      $85,990,448
- ----------------------------------------------------
Shares issued in 
connection with 
reinvestment of 
distributions                41,252        1,212,410
- ----------------------------------------------------
                          2,758,175       87,202,858

Shares 
repurchased              (1,465,953)     (46,403,109)
- ----------------------------------------------------
Net increase              1,292,222      $40,799,749
- ----------------------------------------------------
                                Six months ended 
                               February 29, 1996
- ----------------------------------------------------
Class M                     Shares         Amount
- ----------------------------------------------------
Shares sold                 125,718       $5,231,981
- ----------------------------------------------------
Shares issued in 
connection with 
reinvestment of 
distributions                 1,093           44,781
- ----------------------------------------------------
                            126,811        5,276,762

Shares 
repurchased                 (37,819)      (1,579,441)
- ----------------------------------------------------
Net increase                 88,992       $3,697,321
- ----------------------------------------------------
                               July 3, 1995 
                              (commencement
                             of operations) to
                              August 31, 1995
- ----------------------------------------------------
Class M                      Shares         Amount
- ----------------------------------------------------
Shares sold                   8,913         $309,595
- ----------------------------------------------------
Shares issued in 
connection with 
reinvestment of 
distributions                    --               --
- ----------------------------------------------------
                              8,913          309,595

Shares 
repurchased                     (43)          (1,539)
- ----------------------------------------------------
Net increase                  8,870          308,056
- ----------------------------------------------------



Our commitment to quality service

*CHOOSE AWARD-WINNING SERVICE

Putnam Investor Services has won the DALBAR Quality Tested Service Seal 
for the past six years. In 1995, over 146,000 tests of 56 shareholder 
service components demonstrated that Putnam outperformed the industry 
standard in every category.

*HELP YOUR INVESTMENT GROW

Set up a systematic program for investing with as little as $25 a month 
from a Putnam money market fund or from your checking or savings 
account.*

*SWITCH FUNDS EASILY

You can move money from one account to another with the same class of 
shares without a service charge. (This privilege is subject to change or 
termination.)

*ACCESS YOUR MONEY QUICKLY

You can get checks sent regularly or redeem shares any business day at 
the then-current net asset value, which may be more or less than the 
original cost of the shares.

For details about any of these or other services, contact your financial 
advisor or call the toll-free number shown below and speak with a 
helpful Putnam representative.

To make an additional investment in this or any other Putnam fund, 
contact your financial advisor or call our toll-free number: 
1-800-225-1581.
     
* Regular investing of course, does not guarantee a profit or protect
  against a loss in a declining market.



Fund information


INVESTMENT MANAGER
Putnam Investment 
Management, Inc.
One Post Office Square
Boston, MA 02109

MARKETING SERVICES
Putnam Mutual Funds Corp. 
One Post Office Square
Boston, MA 02109

CUSTODIAN
Putnam Fiduciary Trust Company

LEGAL COUNSEL
Ropes & Gray

TRUSTEES
George Putnam, Chairman
William F. Pounds, Vice Chairman
Jameson Adkins Baxter
Hans H. Estin
John A. Hill
Elizabeth T. Kennan
Lawrence J. Lasser
Robert E. Patterson
Donald S. Perkins
George Putnam, III
Eli Shapiro
A.J.C. Smith
W. Nicholas Thorndike

OFFICERS
George Putnam
President 

Charles E. Porter
Executive Vice President

Patricia C. Flaherty
Senior Vice President

John D. Hughes
Senior Vice President and Treasurer

Lawrence J. Lasser
Vice President 

Gordon H. Silver
Vice President 

Peter Carman
Vice President

Brett C. Browchuk
Vice President

John J. Morgan, Jr.
Vice President

Carol McMullen
Vice President

Joanne Soja
Vice President and Fund Manager 

William N. Shiebler
Vice President 

Paul M. O'Neil
Vice President 

Beverly Marcus
Clerk and Assistant Treasurer

This report is for the information of shareholders of Putnam Health 
Sciences Trust. It may also be used as sales literature when preceded or 
accompanied by the current prospectus, which gives details of sales 
charges, investment objectives, and operating policies of the fund, and 
the most recent copy of Putnam's Quarterly Performance Summary.  For 
more information, or to request a prospectus, call toll free: 1-800-225-
1581.

Shares of mutual funds are not deposits or obligations of, or guaranteed 
or endorsed by, any financial institution; are not insured by the 
Federal Deposit Insurance Corporation (FDIC), the Federal Reserve Board 
or any other agency; and involve risk, including the possible loss of 
the principal amount invested.



The Putnam Funds
One Post Office Square
Boston, Massachusetts 02109


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Bulk Rate 
U.S. Postage
PAID
Putnam
Investments
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24025-021/335/2AB          4/96




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