Putnam Investments
One Post Office Square
Boston, MA 02109
January 5, 2001
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, DC 20549
RE: Putnam Health Sciences Trust (Reg. No. 2-75863) (811-3386)
(the "Fund")
Post-Effective Amendment No. 19 to Registration Statement on
Form N-1A
Ladies and Gentlemen:
Pursuant to Rule 497(j) under the Securities Act of 1933, as amended,
the Fund hereby certifies that the form of Prospectuses and Statement of
Additional Information that would have been filed on behalf of the Fund
pursuant to Rule 497(c) upon the effectiveness of Post-Effective
Amendment No. 19 to the Fund's Registration Statement on Form N-1A (the
"Amendment") would not have differed from that contained in the
Amendment, which is the most recent amendment to such Registration
Statement and was filed electronically on December 28, 2000.
Comments or questions concerning this certificate may be directed to
Kathleen M. Moynihan at 1-800-225-2465, ext. 11796.
Very truly yours,
PUTNAM HEALTH SCIENCES TRUST
/s/ Gordon H. Silver
By: ------------------------
Gordon H. Silver
Vice President
cc: Vanda Shellock, Ropes & Gray
