GENERAL AMERICAN INVESTORS CO INC
13F-HR, 1999-05-13
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, DC  20549

                                    Form 13F

                              FORM 13F COVER PAGE

Report for the Calendar Year or Quarter Ended:   March 31, 1999

Institutional Investment Manager Filing this Report:
Name:    General American Investors Company, Inc.
Address: 450 Lexington Avenue, Suite 3300
         New York, NY  10017

13F File Number: 28-461

The institutional investment manager filing this report and the person by whom 
it is signed hereby represent that the person signing the report is authorized 
to submit it, that all information contained herein is true, correct and 
complete, and that it is understood that all required items, statements, 
schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report:
Name:  Eugene L. DeStaebler, Jr.
Title: Vice-President, Administration
Phone: 212-916-8400
Signature, Place and Date of Signing:
     Eugene L. DeStaebler, Jr.     New York, NY      May 13, 1999

Report Type  (Check only one.):

[x]       13F HOLDINGS REPORT
[ ]       13F NOTICE
[ ]       13F COMBINATION REPORT

List of Other Managers Reporting for this Manager:
    NONE

I am signing this report as required by the Securities Exchange Act of 1934.
<PAGE>
                     FORM 13F SUMMARY PAGE

Report Summary:
Number of Other Included Managers:      0
Form 13F Information Table Entry Total: 56
Form 13F Information Table Value Total: $719,865,954

<PAGE>
<TABLE>

      NAME OF ISSUER         TITLE    CUSIP          FAIR      SHARES OR          INVEST. DISC.    OTHER      VOTING AUTHORITY
                              OF      NUMBER        MARKET     PRINCIPAL  SH/               SHARED  MGRS.
                             CLASS                   VALUE      AMOUNT    PRN    SOLE SHARED OTHER        SOLE     SHARED   NONE
                                                                                 (A)   (B)   (C)          (A)       (B)      (C)
 ----------------------------------------------------------------------------------------------------------------------------------
 <S>                                             <C>           <C>                                      <C>
 Adams Express Company      COMMON 006212104       1,228,247      45,281  SH      X                        45,281
 American International Gro COMMON 026874107      15,681,250     130,000  SH      X                       130,000
 Annuity and Life Re (Holdi COMMON G03910109      11,037,188     482,500  SH      X                       482,500
 AmerUs Life Holdings, Inc. COMMON 030732101      10,800,000     450,000  SH      X                       450,000
 AMR Corporation            COMMON 001765106      22,253,750     380,000  SH      X                       380,000
 Buffets, Inc.              COMMON 119882108       9,875,000   1,000,000  SH      X                     1,000,000
 BioReliance Corporation    COMMON 090951104       2,060,500     317,000  SH      X                       317,000
 Berkshire Hathaway Inc.    COMMON 084670108      22,491,000         315  SH      X                           315
 CCB Financial Corp.        COMMON 124875105      11,731,563     217,000  SH      X                       217,000
 Cephalon, Inc.             COMMON 156708109         546,875      62,500  SH      X                        62,500
 Consolidated Stores Corpor COMMON 210149100      10,609,375     350,000  SH      X                       350,000
 Centocor, Inc.             COMMON 152342101       3,693,750     100,000  SH      X                       100,000
 Cox Communications, Inc. - COMMON 224044107      19,662,500     260,000  SH      X                       260,000
 Cisco Systems, Inc.        COMMON 17275R102      24,651,563     225,000  SH      X                       225,000
 Daimler Chrysler AG        COMMON D1668R123      18,964,563     221,000  SH      X                       221,000
 Deere & Company            COMMON 244199105       3,862,500     100,000  SH      X                       100,000
 DuPont Photomasks, Inc.    COMMON 26613X101       3,962,500     100,000  SH      X                       100,000
 Ford Motor Company         COMMON 345370100      28,343,750     500,000  SH      X                       500,000
 First Midwest Bancorp, Inc COMMON 320867104       9,595,000     252,500  SH      X                       252,500
 Golden West Financial      COMMON 381317106      15,280,000     160,000  SH      X                       160,000
 GelTex Pharmaceuticals, In COMMON 368538104       4,218,750     300,000  SH      X                       300,000
 Huntington Bancshares      COMMON 446150104       5,414,063     175,000  SH      X                       175,000
 The Home Depot, Inc.       COMMON 437076102     105,513,750   1,695,000  SH      X                     1,695,000
 Huntingdon Life Sciences   COMMON 445891203       1,209,969     624,500  SH      X                       624,500
 IDEC Pharmaceuticals Corpo COMMON 449370105      21,320,625     415,000  SH      X                       415,000
 Interim Services Inc.      COMMON 45868P100       6,000,000     400,000  SH      X                       400,000
 Kennametal Inc.            COMMON 489170100       5,287,500     300,000  SH      X                       300,000
 Lam Research Corporation   COMMON 512807108      14,500,000     500,000  SH      X                       500,000
 Magainin Pharmaceuticals I COMMON 559036108         468,750     300,000  SH      X                       300,000
 MetaCreations Corporation  COMMON 591016100       2,043,750     300,000  SH      X                       300,000
 Medtronic, Inc.            COMMON 585055106      11,859,375     165,000  SH      X                       165,000
 MedImmune, Inc. 7% Convert CONV C 584699AAO      13,860,375   2,300,000  PRN     X                     2,300,000
 Philip Morris Companies In COMMON 718154107      10,556,250     300,000  SH      X                       300,000
 Molex Incorporated Class A COMMON 608554200      10,350,000     400,000  SH      X                       400,000
 M&T Bank Corporation       COMMON 55261F104      21,555,000      45,000  SH      X                        45,000
 Annaly Mortgage Management COMMON 035710409       5,500,000     550,000  SH      X                       550,000
 NAC Re Corporation         COMMON 628907107       8,912,125     166,000  SH      X                       166,000
 NTL Incorporated           COMMON 629407107      25,226,250     310,000  SH      X                       310,000
 pcOrder.com, Inc.          COMMON 70453H107       2,548,125      45,000  SH      X                        45,000
 PepsiCo, Inc.              COMMON 713448108       7,837,500     200,000  SH      X                       200,000
 Pfizer Inc.                COMMON 717081103      41,625,000     300,000  SH      X                       300,000
 Ryder System, Inc.         COMMON 783549108       5,525,000     200,000  SH      X                       200,000
 Everest Reinsurance Holdin COMMON 299808105      10,447,813     335,000  SH      X                       335,000
 Repsol, S.A. - ADR         COMMON 76026T205      12,812,500     250,000  SH      X                       250,000
 ReliaStar Financial Corp.  COMMON 75952U103       6,074,063     142,500  SH      X                       142,500
 Reuters Group plc-ADR      COMMON 76132M102       8,166,250      94,000  SH      X                        94,000
 Royce Value Trust          COMMON 780910105         612,633      54,153  SH      X                        54,153
 Seagate Technology, Inc.   COMMON 811804103      12,711,875     430,000  SH      X                       430,000
 Sun Trust Banks, Inc.      COMMON 867914103      14,940,000     240,000  SH      X                       240,000
 The TJX Companies, Inc.    COMMON 872540109       3,060,000      90,000  SH      X                        90,000
 TriQuint Semiconductor, In COMMON 89674K103       1,517,000      82,000  SH      X                        82,000
 Transatlantic Holdings, In COMMON 893521104      15,000,000     200,000  SH      X                       200,000
 Tri-Continental Corporatio COMMON 895436103       1,357,664      46,816  SH      X                        46,816
 Waste Management, Inc.     COMMON 94106L109      20,412,500     460,000  SH      X                       460,000
 Wal-Mart Stores, Inc.      COMMON 931142103      32,265,625     350,000  SH      X                       350,000
 Williams-Sonoma, Inc.      COMMON 969904101       2,825,000     100,000  SH      X                       100,000
</TABLE>


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