GENERAL AMERICAN INVESTORS CO INC
13F-HR, 2000-05-11
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, DC  20549

                                    Form 13F

                              FORM 13F COVER PAGE

Report for the Calendar Year or Quarter Ended:   March 31, 2000

Institutional Investment Manager Filing this Report:
Name:    General American Investors Company, Inc.
Address: 450 Lexington Avenue, Suite 3300
         New York, NY  10017

13F File Number: 28-461

The institutional  investment  manager filing this report and the person by whom
it is signed hereby  represent  that the person signing the report is authorized
to  submit  it,  that all  information  contained  herein is true,  correct  and
complete,  and  that it is  understood  that  all  required  items,  statements,
schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report:
Name:  Eugene L. DeStaebler, Jr.
Title: Vice-President, Administration
Phone: 212-916-8400
Signature, Place and Date of Signing:
     Eugene L. DeStaebler, Jr.     New York, NY      May 11, 2000

Report Type  (Check only one.):

[x]       13F HOLDINGS REPORT
[ ]       13F NOTICE
[ ]       13F COMBINATION REPORT

List of Other Managers Reporting for this Manager:
    NONE

I am signing this report as required by the Securities Exchange Act of 1934.

<PAGE>

                     FORM 13F SUMMARY PAGE

Report Summary:
Number of Other Included Managers:      0
Form 13F Information Table Entry Total: 78
Form 13F Information Table Value Total: $1,029,497,411

<PAGE>
<TABLE>

      NAME OF ISSUER         TITLE    CUSIP          FAIR      SHARES OR          INVEST. DISC.    OTHER      VOTING AUTHORITY
                              OF      NUMBER        MARKET     PRINCIPAL  SH/               SHARED  MGRS.
                             CLASS                   VALUE      AMOUNT    PRN    SOLE SHARED OTHER        SOLE     SHARED   NONE
                                                                                 (A)   (B)   (C)          (A)       (B)      (C)
 ------------------------------------------------------------------------------------------------------------------------------- ---
 <S>                                             <C>           <C>                                      <C>
 ADE Corporation            COMMON 00089C107       1,100,000      50,000  SH      X                        50,000
 Adams Express Company      COMMON 006212104       1,803,232      48,247  SH      X                        48,247
 American International Gro COMMON 026874107      16,425,000     150,000  SH      X                       150,000
 Annuity and Life Re (Holdi COMMON G03910109      13,585,000     522,500  SH      X                       522,500
 AmerUs Life Holdings, Inc. COMMON 030732101       6,796,875     375,000  SH      X                       375,000
 AMR Corporation            COMMON 001765106      22,312,500     700,000  SH      X                       700,000
 Buffets, Inc.              COMMON 119882108      17,046,484   1,887,500  SH      X                     1,887,500
 BioReliance Corporation    COMMON 090951104       1,703,875     317,000  SH      X                       317,000
 Berkshire Hathaway Inc.    COMMON 084670108      18,018,000         315  SH      X                           315
 Brooks Automation, Inc.    COMMON 11434A100      10,937,500     175,000  SH      X                       175,000
 Brooktrout Technology, Inc COMMON 114580103       5,075,000     175,000  SH      X                       175,000
 CCB Financial Corp.        COMMON 124875105       6,858,750     155,000  SH      X                       155,000
 CCC Information Services G COMMON 12487Q109       2,150,000     100,000  SH      X                       100,000
 Central Securities Corpora COMMON 155123102       2,231,730      65,760  SH      X                        65,760
 Consolidated Stores Corpor COMMON 210149100       2,275,000     200,000  SH      X                       200,000
 Cox Communications, Inc. - COMMON 224044107      25,220,000     520,000  SH      X                       520,000
 Compaq Computer Corporatio COMMON 204493100       4,012,500     150,000  SH      X                       150,000
 Cirrus Logic, Inc.         COMMON 172755100       6,843,750     375,000  SH      X                       375,000
 Cisco Systems, Inc.        COMMON 17275R102      55,278,438     715,000  SH      X                       715,000
 C-Cube Microsystems Inc.   COMMON 125015107       5,096,875      70,000  SH      X                        70,000
 Covance Inc.               COMMON 222816100       5,375,000     500,000  SH      X                       500,000
 DuPont Photomasks, Inc.    COMMON 26613X101       6,952,500     120,000  SH      X                       120,000
 EMCORE Corporation         COMMON 290846104      23,012,500     200,000  SH      X                       200,000
 Emmis Communications Corpo COMMON 291525103       2,325,000      50,000  SH      X                        50,000
 Ethan Allen Interiors, Inc COMMON 297602104       6,875,000     275,000  SH      X                       275,000
 Ford Motor Company         COMMON 345370100      29,859,375     650,000  SH      X                       650,000
 First Midwest Bancorp, Inc COMMON 320867104       9,093,750     375,000  SH      X                       375,000
 Fusion Medical Technologie COMMON 361128101         828,750      42,500  SH      X                        42,500
 Golden West Financial      COMMON 381317106      14,970,000     480,000  SH      X                       480,000
 GelTex Pharmaceuticals, In COMMON 368538104       5,025,000     300,000  SH      X                       300,000
 The Home Depot, Inc.       COMMON 437076102     138,352,500   2,145,000  SH      X                     2,145,000
 Harris Corporation         COMMON 413875105       3,456,250     100,000  SH      X                       100,000
 Huntingdon Life Sciences   COMMON 445891203         590,063     524,500  SH      X                       524,500
 IDEC Pharmaceuticals Corpo COMMON 449370105      37,826,250     385,000  SH      X                       385,000
 Interim Services Inc.      COMMON 45868P100       7,425,000     400,000  SH      X                       400,000
 John Hancock Financial Ser COMMON 410145106       7,225,000     400,000  SH      X                       400,000
 Johnson & Johnson          COMMON 478160104       8,956,875     127,500  SH      X                       127,500
 Lam Research Corporation   COMMON 512807108      49,681,406   1,102,500  SH      X                     1,102,500
 Magainin Pharmaceuticals I COMMON 559036108       1,282,500     270,000  SH      X                       270,000
 Manugistics Group, Inc.    COMMON 565011103      12,750,000     250,000  SH      X                       250,000
 MetaCreations Corporation  COMMON 591016100       4,887,500     230,000  SH      X                       230,000
 Medtronic, Inc.            COMMON 585055106      15,431,250     300,000  SH      X                       300,000
 MedImmune, Inc.            COMMON 584699102      11,840,500      68,000  SH      X                        68,000
 Mitel Corporation          COMMON 606711109       6,754,688     275,000  SH      X                       275,000
 Philip Morris Companies In COMMON 718154107       3,168,750     150,000  SH      X                       150,000
 Molex Incorporated Class A COMMON 608554200      27,556,875     621,000  SH      X                       621,000
 M&T Bank Corporation       COMMON 55261F104      20,092,500      45,000  SH      X                        45,000
 NCR Corporation            COMMON 62886E108       8,025,000     200,000  SH      X                       200,000
 Annaly Mortgage Management COMMON 035710409       4,950,000     550,000  SH      X                       550,000
 NTL Incorporated           COMMON 629407107      25,523,437     275,000  SH      X                       275,000
 PepsiCo, Inc.              COMMON 713448108       6,975,000     200,000  SH      X                       200,000
 Pfizer Inc.                COMMON 717081103      32,357,813     885,000  SH      X                       885,000
 PRI Automation, Inc.       COMMON 69357H106       8,251,875     135,000  SH      X                       135,000
 Quintiles Transnational Co COMMON 748767100       4,095,000     240,000  SH      X                       240,000
 Everest Reinsurance Holdin COMMON 299808105      27,731,250     850,000  SH      X                       850,000
 Repsol, S.A. - ADR         COMMON 76026T205      14,918,750     700,000  SH      X                       700,000
 Reinsurance Group of Ameri COMMON 759351109       8,334,375     350,000  SH      X                       350,000
 ReliaStar Financial Corp.  COMMON 75952U103      16,937,500     500,000  SH      X                       500,000
 Royce Value Trust          COMMON 780910105         826,791      59,856  SH      X                        59,856
 Saks Incorporated          COMMON 79377W108      10,150,000     700,000  SH      X                       700,000
 Synopsys, Inc.             COMMON 871607107       4,875,000     100,000  SH      X                       100,000
 SPSS Inc.                  COMMON 78462K102       2,873,375      90,500  SH      X                        90,500
 Sun Trust Banks, Inc.      COMMON 867914103      13,571,250     235,000  SH      X                       235,000
 The ServiceMaster Company  COMMON 81760N109       8,848,125     786,500  SH      X                       786,500
 The TJX Companies, Inc.    COMMON 872540109      27,512,500   1,240,000  SH      X                     1,240,000
 The Thermo Opportunity Fun COMMON 883580101         145,188      11,500  SH      X                        11,500
 Thermo Electron Corporatio COMMON 883556102       3,565,625     175,000  SH      X                       175,000
 TriQuint Semiconductor, In COMMON 89674K103       3,381,000      46,000  SH      X                        46,000
 Transatlantic Holdings, In COMMON 893521104      17,100,000     200,000  SH      X                       200,000
 Sabre Holdings Corporation COMMON 785905100      18,432,500     505,000  SH      X                       505,000
 Tri-Continental Corporatio COMMON 895436103       1,352,546      53,041  SH      X                        53,041
 USA Networks, Inc.         COMMON 902984103         564,063      25,000  SH      X                        25,000
 Uniroyal Technology Corpor COMMON 909163107      18,001,000     383,000  SH      X                       383,000
 Wind River Systems, Inc.   COMMON 973149107       5,437,500     150,000  SH      X                       150,000
 Waste Management, Inc.     COMMON 94106L109       5,652,938     413,000  SH      X                       413,000
 Wal-Mart Stores, Inc.      COMMON 931142103      32,205,000     570,000  SH      X                       570,000
 Western Wireless Corporati COMMON 95988E204       2,176,094      47,500  SH      X                        47,500
 XL Capital Ltd.            COMMON G98255105       8,361,625     151,000  SH      X                       151,000
</TABLE>


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