GENERAL MOTORS ACCEPTANCE CORP
424B3, 1999-09-24
PERSONAL CREDIT INSTITUTIONS
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Supplement Dated September 22, 1999                     Rule 424(b)(3)
(To Prospectus Dated April 22, 1999)                File No. 333-76483

                     GENERAL MOTORS ACCEPTANCE CORPORATION
                       Medium-Term Notes - Floating Rate
____________________________________________________________________________
Agent:                       Morgan Stanley
Principal Amount:            $25,000,000.00
Agent's Discount
  or Commission:             $23,725.00
Net Proceeds to Company:     $24,976,275.00
Initial Interest Rate:       Reset on the Issue Date (also an Interest
                             Reset Date).
Issue Date:                  09/22/99
Maturity Date:               09/21/01
____________________________________________________________________________

Calculation Agent:  GMAC

Interest Calculation:
     /X/  Regular Floating Rate Note

      Interest Rate Basis: / / CD Rate             / / Commercial Paper Rate
                           / / Prime Rate          /X/ Federal Funds Rate
                           / / LIBOR (see below)   / / Treasury Rate
                           / / Other
                           (see attached)

      If LIBOR, Designated LIBOR Page / / Reuters Page: / / or
        / / Telerate Page: 3750


Interest Reset Dates: Each Business Day to but excluding Maturity Date,
                      commencing September 22, 1999.

Interest Payment Dates: Each March 21, June 21, September 21, and December 21
                        commencing on December 21, 1999 and ending September
                        21, 2001.

Index Maturity:         1 day
Spread (+/-):           +.50%

Day Count Convention:
      /X/ Actual/360 for the period from  09/22/99 to 09/21/01
      / / Actual/Actual for the period from  / /   to  / /
      / / 30/360 for the period from  / /   to  / /

Redemption:
      /X/ The Notes cannot be redeemed prior to the Stated Maturity Date.
      / / The Notes may be redeemed prior to Stated Maturity Date.
      / / Initial Redemption Date:
          Initial Redemption Percentage: ___%
          Annual Redemption Percentage Reduction:  ___% until Redemption
          Percentage is 100% of the Principal Amount.


Repayment:
      /X/ The Notes cannot be repaid prior to the Maturity Date.
      / / The Notes can be repaid prior to the Maturity Date at the option of
          the holder of the Notes. (See Below)
      / / Optional Repayment Date(s):
          Repayment Price:    %

Currency:
      Specified Currency: U.S. (If other than U.S. dollars, see attached)
      Minimum Denominations: ___________ (Applicable only if Specified
      Currency is other than U.S. dollars)

Original Issue Discount:  / / Yes     /X/ No
      Total Amount of OID:            Yield to Maturity:
      Initial Accrual Period:

Form:   /X/  Book-Entry                / /  Certificated

Other: /X/  Principal                 / /  Agent

If as principal:
      /X/  The Notes are being offered at varying prices related to prevailing
           market prices at the time of resale.
      / /  The Notes are beings offered at a fixed initial public offering
           price of __% of principal amount.

If as agent:
     The Notes are being offered at a fixed initial public offering price of
     __% of principal amount.

OTHER TERMS

     The Interest Determination Date with respect to each Interest Reset Date
will be the Business Day immediately preceding such Interest Reset Date.  The
Federal Funds Rate for each Interest Period will be determined by the
Calculation Agent (as defined below) in accordance with the following
provisions.

     Interest payable on the Notes will include interest accrued from and
including the Issue Date or from and including the last Interest Payment Date
to which interest has been paid to, but excluding, the next succeeding
Interest Payment Date, or Maturity Date, as the case may be.

     All calculations made by the Calculation Agent in the absence of manifest
error shall be conclusive for all purposes and binding on the Company and the
holders of the Notes.








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