GENERAL MOTORS CORP
SC 13D/A, 1995-05-08
MOTOR VEHICLES & PASSENGER CAR BODIES
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                                UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, DC  20549 
                                             

                                 SCHEDULE 13D

                  Under the Securities Exchange Act of 1934
                              (Amendment No. 15)

                          GENERAL MOTORS CORPORATION     
                               (Name of Issuer)

               Class H Common Stock, par value $0.10 per share
                        (Title of Class of Securities)

                                   370442 50 1     
                                (CUSIP Number)

                           Craig A. Alexander, Esq.
               Deputy General Counsel and Assistant Secretary 
                       Howard Hughes Medical Institute
                4000 Jones Bridge Road, Chevy Chase, MD  20815
                           Tel. No. (301) 215-8841                 
           (Name, Address and Telephone Number of Person Authorized
                    to Receive Notices and Communications)

                                May 4, 1995                        
           (Date of Event which Requires Filing of this Statement)

                    If the filing person has previously filed a
          statement on Schedule 13G to report the acquisition which
          is the subject of this Schedule 13D, and is filing this
          Schedule because of Rule 13d-1(b)(3) or (4), check the
          following box:  [ ]

                    Check the following box if a fee is being paid
          with this statement:  [ ]


                                SCHEDULE 13D

      CUSIP No. 370442 50 1

       1.  NAME OF REPORTING PERSON 
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON.

           Howard Hughes Medical Institute
           I.R.S. Identification No. 59-0735717

       2.  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP 
                                                  (a)  ( )
                                                  (b)  ( )
       3.  SEC USE ONLY

       4.  SOURCE OF FUNDS
           OO

       5.  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
           PURSUANT TO ITEMS 2(d) or 2(e)
                                                       ( )

       6.  CITIZENSHIP OR PLACE OF ORGANIZATION
           State of Delaware

        NUMBER OF                           7.  SOLE VOTING POWER
         SHARES                                 2,503,800
      BENEFICIALLY                          8.  SHARED VOTING POWER
        OWNED BY                                0
          EACH
       REPORTING                            9.  SOLE DISPOSITIVE POWER
         PERSON                                 2,503,800
          WITH                             10.  SHARED DISPOSITIVE POWER
                                                0

      11.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
           PERSON
                 2,503,800
      12.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
           CERTAIN SHARES

                                                             ( )
      13.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
           2.6%
      14.  TYPE OF REPORTING PERSON
           CO


          Item 1.   SECURITY AND ISSUER

                    Unchanged.

          Item 2.   IDENTITY AND BACKGROUND

                    Unchanged.

          Item 3.   SOURCE AND AMOUNT OF FUNDS OR OTHER
                    CONSIDERATION

                    Unchanged.

          Item 4.   PURPOSE OF TRANSACTION

                    Unchanged, except as follows (capitalized terms
                    used in this Amendment No. 15 to Schedule 13D
                    and not defined herein have the meaning
                    assigned to them in the Schedule 13D and
                    amendments thereto previously filed by HHMI
                    with respect to its holdings of Class H Stock,
                    in the Class H Stock Agreement, as amended, in
                    the 1992 Agreement or in the Class H Stock Sale
                    Agreement):
           
                    On May 4, 1995, HHMI completed the sale of
                    15,000,000 shares of Class H Stock to the
                    Underwriters pursuant to the terms of the
                    Underwriting Agreement and the Pricing
                    Agreement.  Based upon the purchase price of
                    $37.45 per share, HHMI received $561,750,000 at
                    the closing of the sale.  Pursuant to the Class
                    H Stock Sale Agreement, HHMI has agreed to
                    reimburse GM for GM's out-of-pocket expenses
                    incurred in the connection with the Offering. 
                    As previously reported, HHMI has agreed to
                    refrain from offering to sell, selling or
                    otherwise disposing of Class H Stock or any
                    securities convertible into or exchangeable for
                    Class H Stock for 90 days following the
                    Offering.  HHMI currently holds 2,503,800
                    shares of Class H Stock.  These shares are held
                    as part of HHMI's core investment portfolio. 
                    HHMI will make decisions with respect to the
                    retention or disposition of such shares in the
                    same manner as it deals with other securities
                    in its portfolio.  HHMI has no current plan or
                    intent to sell any shares of its Class H Stock. 
                    HHMI's Class H Stock investment constitutes one
                    of its largest equity positions.

                    Since the filing of Amendment No. 14 to
                    Schedule 13D, HHMI, as described above, has
                    disposed of 15,000,000 shares of Class H Stock.

          Item 5.   INTEREST IN SECURITIES OF THE ISSUER

                    (a)  HHMI owns beneficially 2,503,800 shares of
                         Class H Stock, or approximately 2.6% of
                         the 95,093,416 shares of Class H Stock
                         reported to be outstanding as of March 31,
                         1995 in Amendment No. 2 to the


                         registration statement filed on Form S-3
                         by GM in connection with the Offering.  To
                         the best of HHMI's knowledge, none of the
                         other persons named or referred to in the
                         response to Item 2 hereof beneficially
                         owns any shares of Class H Stock.

                    (b)  Unchanged.

                    (c)  Except for the sale of 15,000,000 shares
                         of Class H Stock to the Underwriters (as
                         described herein), within the last 60
                         days, no transactions in shares of Class H
                         Stock were effected by HHMI or, to the
                         best of HHMI's knowledge, by any of the
                         persons named or referred to in response
                         to Item 2 hereof.

                    (d)  Unchanged.

                    (e)  Unchanged.

          Item 6.   CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR
                    RELATIONSHIPS WITH RESPECT TO SECURITIES OF THE
                    ISSUER

                    Unchanged, except as follows (capitalized terms
                    used in this Amendment No. 15 to Schedule 13D
                    and not defined herein have the meaning
                    assigned to them in the Schedule 13D and
                    amendments thereto previously filed by HHMI
                    with respect to its holdings of Class H Stock,
                    in the Class H Stock Agreement, as amended, in
                    the 1992 Agreement or in the Class H Stock Sale
                    Agreement):

                    The sale by HHMI of 15,000,000 shares of Class
                    H Stock to the Underwriters pursuant to the
                    Underwriting Agreement and the Pricing
                    Agreement was completed on May 4, 1995.  The
                    purchase price paid by the Underwriters to HHMI
                    for the Class H Shares was $37.45 per share. 
                    HHMI received $561,750,000 from the
                    Underwriters at the closing of the sale.

                    HHMI has agreed that during the period
                    beginning from the date of the prospectus and
                    continuing to and including the date 90 days
                    after the date of the Prospectus, not to offer
                    or sell, or solicit offers to purchase, any
                    shares of Class H Stock or any securities which
                    are convertible or exchangeable into Class H
                    Stock, without the written consent of Goldman,
                    Sachs & Co. and Salomon Brothers Inc, except
                    for the shares offered in connection with the
                    Offering.

          Item 7.   MATERIAL TO BE FILED AS EXHIBITS

                    None.



                              S I G N A T U R E

                         After reasonable inquiry and to the best
          of my knowledge and belief, I certify that the
          information set forth in this statement is true, complete
          and correct.

          Dated:  May 8, 1995

                                   HOWARD HUGHES MEDICAL INSTITUTE

                                   \s\ Craig A. Alexander          
                                   Craig A. Alexander, Esq.
                                   Deputy General Counsel           
                                    and Assistant Secretary




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