ALZA CORP
DEF 14A, 1994-03-14
PHARMACEUTICAL PREPARATIONS
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<PAGE>
                            SCHEDULE 14A INFORMATION

           Proxy Statement Pursuant to Section 14(a) of the Securities
                     Exchange Act of 1934 (Amendment No.   )

Filed by the Registrant /X/
Filed by a Party other than the Registrant / /

Check the appropriate box:

/ /  Preliminary Proxy Statement
/X/  Definitive Proxy Statement
/ /  Definitive Additional Materials
/ /  Soliciting Material Pursuant to Section 240.14a-11(c) or Section 240.14a-12

                                ALZA CORPORATION
- -------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)


                                ALZA CORPORATION
- -------------------------------------------------------------------------------
                   (Name of Person(s) Filing Proxy Statement)

Payment of Filing Fee (Check the appropriate box):

/X/  $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), or 14a-6(j)(2).
     (1)
/ /  $500 per each party to the controversy pursuant to Exchange Act Rule
     14a-6(i)(3).
/ /  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

     1)   Title of each class of securities to which transaction applies:


          ---------------------------------------------------------------------

     2)   Aggregate number of securities to which transaction applies:


          ---------------------------------------------------------------------

     3)   Per unit price or other underlying value of transaction computed
          pursuant to Exchange Act Rule 0-11:


          ---------------------------------------------------------------------

<PAGE>


     4)   Proposed maximum aggregate value of transaction:


          ---------------------------------------------------------------------

     Set forth the amount on which the filing fee is calculated and state how it
     was determined.

/ /  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2) and identify the filing for which the offsetting fee was paid
     previously.  Identify the previous filing by registration statement number,
     or the Form or Schedule and the date of its filing.

     1)   Amount Previously Paid:


          ---------------------------------------------------------------------

     2)   Form, Schedule or Registration Statement No.:


          ---------------------------------------------------------------------

     3)   Filing Party:


          ---------------------------------------------------------------------

     4)   Date Filed:


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NOTES:

(1)    Sent by wire transfer to lock box on March 4, 1994.

                                    * * * * *
<PAGE>
                                     [LOGO]

                                ALZA CORPORATION
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                    TO BE HELD APRIL 26, 1994 AT 10:00 A.M.

To the Stockholders of ALZA Corporation:

    NOTICE  IS  HEREBY GIVEN  that the  Annual Meeting  of Stockholders  of ALZA
Corporation will  be held  at 950  Page  Mill Road,  Palo Alto,  California,  on
Tuesday, April 26, 1994 at 10:00 a.m., for the following purposes:

    1.   To elect  three Class I directors  to hold office for  a term ending in
1997 and until their successors are elected;

    2.   To  ratify the  appointment  of Ernst  &  Young as  ALZA's  independent
auditors for the fiscal year ended December 31, 1994; and

    3.   To  transact such other  business as  may properly be  presented at the
meeting and at any adjournments or postponements thereof.

    Only holders of record of Common Stock at the close of business on March  8,
1994 are entitled to notice of, and to vote at, the meeting and any adjournments
or postponements thereof.

                                          By Order of the Board of Directors,

                                                JULIAN N. STERN
                                                   Secretary

Palo Alto, California
March 14, 1994

     WHETHER  OR NOT  YOU PLAN  TO ATTEND THE  ANNUAL MEETING,  PLEASE SIGN THE
 ACCOMPANYING PROXY CARD AND RETURN IT AS SOON AS POSSIBLE IN THE  ACCOMPANYING
 POSTPAID  ENVELOPE.  YOUR DOING  SO  MAY SAVE  ALZA  THE EXPENSE  OF  A SECOND
 MAILING.
<PAGE>
                                ALZA CORPORATION
                                PROXY STATEMENT

To the Stockholders of ALZA Corporation:

    The accompanying proxy is solicited on behalf of the Board of Directors (the
"Board") of ALZA Corporation ("ALZA"), a Delaware corporation, for use at ALZA's
Annual  Meeting of Stockholders (the "Annual Meeting")  to be held at 10:00 a.m.
on Tuesday, April 26, 1994 at ALZA's headquarters located at 950 Page Mill Road,
Palo Alto, California 94304; telephone number (415) 494-5000.

    Only holders of record of ALZA's Common Stock as of the close of business on
March 8, 1994 are entitled to notice of, and to vote at, the Annual Meeting  and
any  adjournments or  postponements thereof.  At the  close of  business on that
date, ALZA had outstanding 81,662,500 shares of its Common Stock, par value $.01
per share. Holders of Common  Stock are entitled to one  vote for each share  of
Common Stock held.

    Any  holder of  Common Stock  giving a proxy  in the  form accompanying this
Proxy Statement has the power to revoke the proxy prior to its use. A proxy  can
be  revoked (i)  by an  instrument of revocation  delivered prior  to the Annual
Meeting to the Secretary of ALZA, (ii) by a duly executed proxy bearing a  later
date  or time than the date or time of  the proxy being revoked, or (iii) at the
Annual Meeting if the stockholder is present and elects to vote in person.  Mere
attendance at the Annual Meeting will not serve to revoke a proxy.

    A  stockholder who abstains from voting on any or all matters will be deemed
present at the meeting for quorum purposes, but will not be deemed to have voted
on the particular matter (or matters) as to which the stockholder has abstained.
Similarly, in the event a nominee (such as a brokerage firm) holding shares  for
beneficial  owners votes on certain  matters pursuant to discretionary authority
or instructions from beneficial  owners, but with respect  to one or more  other
matters  does not  receive instructions from  beneficial owners  and/or does not
exercise discretionary authority  (a so-called "non-vote"),  the shares held  by
the  nominee will be deemed present at  the meeting for quorum purposes but will
not be deemed to have voted on such other matters.

    This Proxy Statement  and the accompanying  proxy card are  being mailed  to
ALZA  stockholders on  or about  March 14,  1994. Directors,  officers and other
employees  of  ALZA  may  solicit  proxies  by  personal  interview,  telephone,
telegraph  or facsimile, without special compensation. Any costs of solicitation
will be borne by ALZA.

                             ELECTION OF DIRECTORS

    ALZA's Certificate of Incorporation provides for three classes of directors:
Class I, Class II and Class III. Only one class of directors is elected at  each
annual meeting of stockholders, each director to serve for a three-year term. In
accordance  with the Certificate  of Incorporation, Class I  directors are to be
elected at the 1994 annual meeting, Class II directors are to be elected at  the
1995 annual meeting and Class III directors are to be elected at the 1996 annual
meeting.

NOMINEES

    Three  Class  I directors  are  to be  elected to  the  Board at  the Annual
Meeting, each to serve until  the annual meeting of  stockholders to be held  in
1997 and until his or her successor has been elected and qualified, or until his
or  her earlier death, resignation or removal.  The nominees for election at the
Annual Meeting are William G. Davis, Martin S. Gerstel and Julian N. Stern.

    All of  the nominees  presently are  directors of  ALZA. If  any nominee  is
unable  or  unwilling  to  serve as  a  director,  proxies may  be  voted  for a
substitute nominee designated by the present  Board. The Board has no reason  to
believe  that any nominee will be unable or  unwilling to serve as a director if
elected. Proxies  received will  be voted  "FOR" the  election of  all  nominees
unless  marked to the contrary. Pursuant to applicable Delaware corporation law,
assuming the presence of a quorum, three

                                       1
<PAGE>
directors will  be elected  from among  those persons  duly nominated  for  such
positions  by a plurality of the votes actually cast by stockholders entitled to
vote at the meeting who  are present in person or  by proxy. Thus, nominees  who
receive  the first, second and  third highest number of  votes in favor of their
election will be elected, regardless of the number of abstentions or non-votes.

    The following  table provides  the names  of the  nominees for  election  as
directors  and each other  director and indicates the  periods during which such
persons have served continuously as directors of ALZA.

<TABLE>
<CAPTION>
                                                                                              DIRECTOR
                                                                                            CONTINUOUSLY
NAME AND POSITIONS WITH ALZA IN ADDITION TO DIRECTOR                                           SINCE
- ------------------------------------------------------------------------------------------  ------------
<S>                                                                                         <C>
NOMINEES (CLASS I DIRECTORS)
  William G. Davis........................................................................      1989
  Martin S. Gerstel.......................................................................      1980
  Julian N. Stern.........................................................................      1982
    Secretary
INCUMBENTS (CLASS II AND CLASS III DIRECTORS)
CLASS II DIRECTORS
  Dr. Robert J. Glaser....................................................................      1987
  Dean O. Morton..........................................................................      1987
  Dr. Jane E. Shaw........................................................................      1989
    President and Chief Operating Officer
CLASS III DIRECTORS
  Dr. Ernest Mario........................................................................      1993
    Co-Chairman of the Board and Chief Executive Officer
  Rudolph A. Peterson.....................................................................      1969
  Isaac Stein.............................................................................      1987
  Dr. Alejandro Zaffaroni.................................................................      1968
    Co-Chairman of the Board and Founder
</TABLE>

BUSINESS EXPERIENCE OF DIRECTORS

    NOMINEES (CLASS I DIRECTORS)

    William G. Davis,  62, is  a Class  I Director  of ALZA  and an  independent
business  consultant. Prior to his retirement from  Eli Lilly & Company in 1984,
Mr. Davis held various senior executive positions during his 27-year tenure with
that company. Mr. Davis  is a director of  ABIOMED, Inc., Collagen  Corporation,
Target Therapeutics, Inc. and Endosonics Corporation.

    Martin  S. Gerstel, 52,  is a Class I  Director of ALZA.  In early 1992, Mr.
Gerstel announced that he intended to retire as ALZA's Chief Executive  Officer.
In  August 1993, Mr.  Gerstel retired as ALZA's  Co-Chairman and Chief Executive
Officer, having  served  in  such  capacity since  1987,  and  as  ALZA's  Chief
Financial Officer, having served in such capacity since 1968. Mr. Gerstel served
as  President of ALZA  from 1982 until  1987 and as  its Chief Operating Officer
from 1980  to 1987.  Mr. Gerstel  is  currently a  half-time employee  of  ALZA,
undertaking special projects as requested by the Chief Executive Officer.

    Julian N. Stern, 69, is a Class I Director of ALZA and has been Secretary of
ALZA since 1968. He is the sole employee of a professional corporation that is a
member  of the  law firm of  Heller, Ehrman, White  & McAuliffe. Mr.  Stern is a
managing director of Affymax N.V.

    INCUMBENTS (CLASS II AND CLASS III DIRECTORS)

    CLASS II DIRECTORS

    Dr. Robert J. Glaser, 75,  is a Class II Director  of ALZA and has been  the
Director  for Medical  Science of the  Lucille P. Markey  Charitable Trust since
1984, and a trustee since 1988. Prior to that

                                       2
<PAGE>
time he was President,  Chief Executive Officer  and a trustee  of the Henry  J.
Kaiser  Family Foundation. Dr. Glaser is  a director of Nellcor Incorporated and
Hanger Orthopedic  Group,  Inc. and  a  managing  director of  Affymax  N.V.  In
February 1991, Dr. Glaser retired as a director of Hewlett-Packard Company after
serving since 1971.

    Dean  O. Morton,  61, is a  Class II Director  of ALZA. In  October 1992 Mr.
Morton retired  as  Executive Vice  President,  Chief Operating  Officer  and  a
director  of Hewlett-Packard Company, where he  had held various positions since
1960. Mr. Morton is a director of Raychem Corporation, Clorox Company, Centigram
Communications Corporation, Metropolitan Series Fund and Metlife Portfolios  and
Tencor  Instruments.  He  is also  a  trustee  of the  State  Street  Research &
MetLife-State Street Funds.

    Dr. Jane E. Shaw,  55, is a Class  II Director of ALZA  and has been  ALZA's
President  and Chief Operating Officer since 1987. Previously, she was Executive
Vice President  of ALZA,  President of  ALZA's Research  Division and  has  held
various  other positions since joining ALZA as a Research Scientist in 1970. Dr.
Shaw is a director of Intel Corporation and McKesson Corporation.

    CLASS III DIRECTORS

    Dr. Ernest Mario, 55, is a Class III director and the Co-Chairman and  Chief
Executive  Officer of  ALZA. Prior  to joining ALZA,  Dr. Mario  served as Chief
Executive of Glaxo Holdings plc, a pharmaceutical corporation, from May 1989  to
March 1993, and as its Deputy Chairman from January 1992 to March 1993. Prior to
that  time, Dr. Mario served  as Chairman and Chief  Executive Officer of Glaxo,
Inc., a  subsidiary  of Glaxo  Holdings,  from July  1988  to May  1989  and  as
President  and Chief  Operating Officer of  Glaxo, Inc., from  September 1986 to
July 1988.  Prior  to  joining  Glaxo, Dr.  Mario  had  held  various  executive
positions with E. R. Squibb & Sons since 1977.

    Rudolph  A. Peterson, 89, is a Class III Director of ALZA, the President and
Chief  Executive  Officer  (retired)  and  honorary  director  of  Bank  America
Corporation  and Bank of America N.T. &  S.A. and the Administrator (retired) of
the United Nations Development Programme.

    Isaac Stein, 47, is a Class III Director of ALZA, and has been President  of
Waverley  Associates, Inc.,  a private  investment firm,  since 1983.  Mr. Stein
served as Chairman of  the Board of  Esprit de Corp from  June 1990 to  December
1992.  Mr. Stein is a trustee of the Benham Group of Mutual Funds and a director
of Raychem Corporation.

    Dr. Alejandro Zaffaroni,  71, is  a Class III  Director and  the founder  of
ALZA.  Dr.  Zaffaroni  has  been  Chairman  of  the  Board  of  ALZA  since 1982
(Co-Chairman since 1987) and was ALZA's Chief Executive Officer from 1968  until
1987.  He was President of  ALZA from 1968 until  1982. Since 1988 Dr. Zaffaroni
has been Chairman and Chief Executive Officer of Affymax N.V., a drug  discovery
company.  He currently spends 50% of his time  on the affairs of ALZA and 50% of
his time on those of Affymax N.V.

MEETINGS AND COMMITTEES OF THE BOARD

    There were nine  meetings of the  full Board during  fiscal year 1993.  Each
director  attended  at least  75%  of the  meetings of  the  full Board  and the
committees of the Board on  which he or she served.  The Board has two  standing
committees,  the Compensation and  Benefits Committee and  the Finance and Audit
Committee. The current members  of the Compensation  and Benefits Committee  are
Dr.  Glaser and Messrs. Morton  and Stein, none of whom  is an employee of ALZA.
The Compensation  and Benefits  Committee,  which met  four times  during  1993,
approves  all of  ALZA's compensation plans,  including the  awarding of options
under ALZA's stock  option plans  and the compensation  arrangements for  ALZA's
senior  management. The Finance and Audit  Committee, which met two times during
fiscal 1993, consults with ALZA's independent auditors concerning their auditing
plan, the results of their  audit, the appropriateness of accounting  principles
used by ALZA and the adequacy of ALZA's general accounting controls. The current
members  of the Finance and Audit Committee are Messrs. Morton, Peterson, Stern,
Davis and Stein, none of whom is an employee of ALZA.

                                       3
<PAGE>
    ALZA has  no  standing nominating  committee.  ALZA's by-laws  provide  that
stockholders  may nominate candidates  for election as  directors by delivery of
written notice  to  ALZA's Secretary  at  least sixty  days  in advance  of  the
stockholders'  meeting or ten days after notice of the meeting is first given to
stockholders, whichever is later.  Any such notice must  set forth the name  and
address  of the  nominating stockholder  and the  nominee, and  such information
concerning both such persons as would  be required by the rules and  regulations
of  the Securities and Exchange  Commission to be included  in a proxy statement
soliciting proxies  for  the  election  of  the  nominee.  The  notice  must  be
accompanied  by the written  consent of the  nominee to serve  as a director, if
elected.

    Each director who is not an employee of ALZA receives an annual retainer fee
of $20,000 and fees of $500 for each meeting day of the Board and any  committee
on  which the  director serves;  the chairmen  of the  Compensation and Benefits
Committee and the Finance  and Audit Committee receive  fees of $1,000 for  each
meeting  day  of their  respective committee  in  lieu of  the $500  fee. ALZA's
nonemployee directors receive options to  purchase Common Stock pursuant to  the
automatic grant provisions of ALZA's 1992 Stock Option Plan.

                             EXECUTIVE COMPENSATION
                           SUMMARY COMPENSATION TABLE

    The  following table sets  forth, with respect to  Dr. Mario, ALZA's current
Chief Executive Officer, Mr. Gerstel, ALZA's former Chief Executive Officer, and
each of  ALZA's other  four  most highly  compensated executive  officers  whose
salary  and  bonus  compensation from  ALZA  exceeded $100,000  in  fiscal 1993,
certain information relating to compensation paid or accrued for services in all
capacities during the fiscal years indicated.

<TABLE>
<CAPTION>
                                                                                           LONG-TERM
                                                                                         COMPENSATION
                                                                                       -----------------
                                                                                            AWARDS
                                                      ANNUAL COMPENSATION              -----------------
                                          -------------------------------------------     SECURITIES
                                                                        OTHER ANNUAL      UNDERLYING         ALL OTHER
 NAME AND PRINCIPAL POSITION     YEAR       SALARY (1)     BONUS (1)(2) COMPENSATION      OPTIONS (3)     COMPENSATION (4)
- -----------------------------  ---------  ---------------  -----------  -------------  -----------------  ----------------
<S>                            <C>        <C>              <C>          <C>            <C>                <C>
Dr. Ernest Mario                    1993  $    250,000(5)   $  25,000   $    --               750,000       $      6,063
 Co-Chairman and Chief
 Executive Officer
Martin S. Gerstel                   1993       396,118(5)      30,000        --                40,000            217,366
 Former Co-Chairman and Chief       1992       376,704         50,000        --                75,000            171,306
 Executive Officer and Chief        1991       345,600        100,000        --               --
 Financial Officer
Dr. Alejandro Zaffaroni (6)         1993       222,917         15,000        --               --                 148,695
 Co-Chairman                        1992       212,500         20,000        --               --                 120,892
                                    1991       197,856         40,000        --               --
Dr. Jane E. Shaw                    1993       317,921         30,000        --               100,000            111,729
 President and Chief                1992       282,528         40,000        --               --                  95,358
 Operating Officer                  1991       259,200         80,000        --                90,000
Dr. Felix Theeuwes                  1993       246,834         20,000        --                25,000             85,335
 Executive Vice President           1992       231,000         30,000        --               --                  66,865
                                    1991       201,667         40,000        --                66,000
Adrian M. Gerber                    1993       237,450         20,000       43,706(7)          20,000             34,632
 Executive Vice President           1992       224,700         30,000       56,700(7)         --                  30,231
                                    1991       210,000         35,000       56,700(7)         --
</TABLE>

                                       4
<PAGE>

<TABLE>
<S>   <C>
<FN>
- ------------------------
(1)   Amounts shown  include  compensation  earned  and  received  by  executive
      officers as well as amounts deferred at the election of such persons under
      ALZA's Executive Deferral Plans and Tax Deferral Investment Plan.
(2)   Bonuses  consist of amounts paid under ALZA's Executive Incentive Plan and
      PACE Plan.
(3)   The options were granted for a term of ten years. All unvested options are
      subject to  earlier termination  in  the event  of  the termination  of  a
      participant's relationship with ALZA. The options granted to Dr. Mario are
      exercisable  in six annual increments of 125,000 shares each commencing on
      August 10, 1994.  Of the options  granted to Mr.  Gerstel, the option  for
      40,000  shares is fully exercisable on August  10, 1994 and the option for
      75,000 shares is exercisable in  three annual increments of 25,000  shares
      each commencing on April 16, 1993; of the options granted to Dr. Shaw, the
      option  for 100,000 shares is fully exercisable on August 10, 1996 and the
      option for  90,000 shares  is exercisable  in three  annual increments  of
      30,000 shares each commencing on December 15, 1993; of the options granted
      to  Dr. Theeuwes,  the option  for 25,000  shares is  fully exercisable on
      August 10,  1996, the  option for  16,000 shares  is exercisable  in  four
      annual  increments of 4,000 shares each commencing on January 24, 1993 and
      the remainder of the options are exercisable in five annual increments  of
      10,000  shares  each commencing  on July  19, 1992;  and the  20,000 share
      option granted to Mr. Gerber is fully exercisable on August 10, 1996.  All
      options  were granted at market  value on the date  of grant. In the event
      that certain change  in control events  were to occur,  all options  would
      become  immediately exercisable.  The option  exercise price  may be paid,
      subject to certain conditions, by delivery of already owned shares or with
      the proceeds  from the  sale of  the option  shares. The  tax  withholding
      obligations  related  to  the exercise  may  be paid,  subject  to certain
      conditions, by delivery of already-owned shares or by offset of the shares
      issuable upon exercise  of the  option. Under  the terms  of ALZA's  stock
      option  plans, the Compensation and Benefits Committee retains discretion,
      subject to plan  limits, to reprice  options and to  otherwise modify  the
      terms (including exercise price) of outstanding options.
(4)   Amounts  shown for the fiscal year ended December 31, 1993 consist of: (i)
      amounts contributed by  ALZA to  the participants'  accounts under  ALZA's
      Retirement Plan as follows: $18,189 for Mr. Gerstel, $24,690 for Dr. Shaw,
      $20,426  for Dr.  Theeuwes, and $26,418  for Mr. Gerber;  and (ii) amounts
      representing  interest  in  excess  of  120%  of  the  applicable  federal
      long-term  rate on  amounts deferred  at the  election of  the participant
      under ALZA's Executive Deferral Plans.  Such reportable interest for  1993
      totalled  $6,063 for Dr. Mario, $199,177 for Mr. Gerstel, $148,695 for Dr.
      Zaffaroni, $87,039 for Dr. Shaw, $51,395 for Dr. Theeuwes, and $8,214  for
      Mr.  Gerber. Amounts shown for Dr.  Theeuwes also include $13,514 received
      as the recipient of ALZA's Founder's Award for 1993.
(5)   Mr. Gerstel  retired as  Co-Chairman, Chief  Executive Officer  and  Chief
      Financial Officer of ALZA in August 1993 but remained a full time employee
      of  ALZA for the  remainder of the  year. Dr. Mario  joined ALZA in August
      1993; compensation reflected for Dr. Mario is for a partial year.
(6)   The time Dr. Zaffaroni devoted to the affairs of ALZA was 50% during these
      periods.
(7)   Amounts shown for Mr. Gerber under "Other Annual Compensation" consist  of
      a mortgage differential benefit paid for the years shown.
</TABLE>

                                       5
<PAGE>
                               1993 OPTION GRANTS

    The  following table sets  forth information relating  to options granted in
1993 to Dr. Mario, ALZA's current  Chief Executive Officer, Mr. Gerstel,  ALZA's
former  Chief  Executive Officer,  and  each of  ALZA's  other four  most highly
compensated executive officers  whose salary  and bonus  compensation from  ALZA
exceeded  $100,000 in fiscal 1993. In addition,  in accordance with the rules of
the Securities and Exchange Commission, the table shows hypothetical gains  that
would  exist for such options based on  assumed rates of annual compounded stock
price appreciation of 0%,  5% and 10%  per year from the  date the options  were
granted over the full option term and on the Black-Scholes option pricing model.
The  table also indicates hypothetical gains that  would exist for all shares of
Common Stock outstanding  on the  date the options  were granted  over the  fair
market  value of ALZA Common Stock on such date based on assumed rates of annual
compounded stock price appreciation of 0%, 5% and 10% per year for the ten  year
period beginning on such date.

<TABLE>
<CAPTION>
                            INDIVIDUAL GRANTS
- -------------------------------------------------------------------------  POTENTIAL REALIZABLE VALUE AT
                                        PERCENT OF                         ASSUMED ANNUAL RATES OF STOCK    GRANT DATE
                            NUMBER OF  TOTAL OPTIONS                       PRICE APPRECIATION FOR OPTION     ESTIMATED
                           SECURITIES   GRANTED TO    EXERCISE                        TERM (1)                PRESENT
                           UNDERLYING  EMPLOYEES IN    PRICE   EXPIRATION --------------------------------   VALUE (2)
                             OPTIONS      FISCAL        PER     DATE OF      0%        5%          10%     -------------
           NAME            GRANTED (3)   YEAR (4)      SHARE     OPTION   PER YEAR  PER YEAR    PER YEAR   BLACK-SCHOLES
- -------------------------- ----------- -------------  -------- ---------- -------- ----------- ----------- -------------
<S>                        <C>         <C>            <C>      <C>        <C>      <C>         <C>         <C>
Dr. Ernest Mario              750,000      52.7%      $ 20.25   08/10/03  $  0     $ 9,555,000 $24,202,500 $  7,275,000
Martin S. Gerstel              40,000       2.8         20.25   08/10/03     0         509,600   1,290,800      388,000
Dr. Alejandro Zaffaroni        --         --            --         --       --         --          --           --
Dr. Jane E. Shaw              100,000       7.0         20.25   08/10/03     0       1,274,000   3,227,000      970,000
Dr. Felix Theeuwes             25,000       1.8         20.25   08/10/03     0         318,500     806,750      242,500
Adrian M. Gerber               20,000       1.4         20.25   08/10/03     0         254,800     645,400      194,000
All Shares Outstanding on
 August 10, 1993
  (77,517,198 shares)                                                        0     1.0 Billion 2.5 Billion
<FN>
- ------------------------
(1)   The  amounts  represent certain  assumed  rates of  appreciation  over the
      exercise price per share  (before taxes). Actual gains,  if any, on  stock
      option  exercises and  Common Stock holdings  are dependent  on the future
      performance of the Common Stock. There can be no assurance that any of the
      values reflected in this table will be achieved.
(2)   The amounts shown  are based  on a modified  Black-Scholes option  pricing
      model.  The estimated present values assume (i) a risk-free rate of return
      of 6.13%  (which is  the yield  as  of August  10, 1993  on a  U.S.  Strip
      Treasury  zero-coupon bond expiring  in August 2003),  (ii) 41% volatility
      (which is the volatility of the  Common Stock for the 36 months  preceding
      the date of grant) and (iii) a ten year option term. A discount of 25% was
      applied  to  the  option  value  yielded  by  the  model  to  reflect  the
      nontransferability of  employee  options.  The  actual  gain  realized  on
      options  will depend on the future price of the Common Stock and cannot be
      accurately forecast by application of an option pricing model.
(3)   For a description of the material terms of the options, see footnote 3  of
      the Summary Compensation Table.
(4)   Based  on  the  total number  of  options granted  during  1993, excluding
      options granted to consultants and non-employee directors.
</TABLE>

                                       6
<PAGE>
       1993 AGGREGATED OPTION EXERCISES AND FISCAL YEAR-END OPTION VALUES

    The following table  sets forth with  respect to Dr.  Mario, ALZA's  current
Chief Executive Officer, Mr. Gerstel, ALZA's former Chief Executive Officer, and
each  of  ALZA's other  four most  highly  compensated executive  officers whose
salary and  bonus  compensation from  ALZA  exceeded $100,000  in  fiscal  1993,
certain  information relating to options exercised during fiscal 1993 and fiscal
year-end option values.

<TABLE>
<CAPTION>
                                                            NUMBER OF SECURITIES     VALUE OF UNEXERCISED IN-THE-
                                                           UNDERLYING UNEXERCISED      MONEY OPTIONS AT FISCAL
                                 SHARES                  OPTIONS AT FISCAL YEAR-END          YEAR-END (2)
                               ACQUIRED ON     VALUE     --------------------------  ----------------------------
            NAME                EXERCISE    REALIZED (1) EXERCISABLE  UNEXERCISABLE   EXERCISABLE   UNEXERCISABLE
- -----------------------------  -----------  -----------  -----------  -------------  -------------  -------------
<S>                            <C>          <C>          <C>          <C>            <C>            <C>
Dr. Ernest Mario                   --        $  --           --            750,000   $    --        $   6,000,000
Martin S. Gerstel                  --           --           25,000         90,000        --              320,000
Dr Alejandro Zaffaroni             --           --           --            --             --             --
Dr. Jane E. Shaw                   20,000      371,250      116,000        160,000       1,540,500        800,000
Dr. Felix Theeuwes                 --           --           28,000         67,000          76,500        228,500
Adrian M. Gerber                   --           --           40,000         60,000         450,000        610,000
<FN>
- ------------------------
(1)   Market value  of underlying  securities  at the  exercise date  minus  the
      exercise price.
(2)   Market  value of underlying  securities at fiscal  year-end ($28.25) minus
      the exercise price of "in-the-money" options.
</TABLE>

                   COMPENSATION AND BENEFITS COMMITTEE REPORT
                           ON EXECUTIVE COMPENSATION

    The Compensation and Benefits  Committee (the "Committee")  of the Board  is
generally  responsible for decisions  concerning the compensation  to be paid to
ALZA's executive officers.  The Committee  consists of Robert  J. Glaser,  M.D.,
(Chairman),  Dean O.  Morton and  Isaac Stein,  each of  whom is  a non-employee
director of ALZA. Mr. Morton joined the committee in November 1993; until August
1993, Julian N. Stern was a member of the Committee. In determining compensation
policies, the Committee  has access  to compensation surveys  for regional  high
technology  companies  (which compete  with ALZA  in  the recruitment  of senior
personnel) and national  pharmaceutical industry  compensation information.  The
Committee  also  consults  with  ALZA's  Senior  Director  of  Compensation  and
Benefits. Set forth below is the report of the Committee with respect to  ALZA's
compensation  policies during  1993 as they  affected the  company's current and
former Chief Executive Officers and the company's other executive officers.

COMPENSATION POLICIES AFFECTING EXECUTIVE OFFICERS

    ALZA's compensation policies affecting  its executive officers are  designed
to  provide  targeted compensation  levels that  are  competitive with  those of
regional high technology companies and national pharmaceutical companies, and to
assist the  company  in  attracting  and  retaining  qualified  executives.  The
Committee  believes that ALZA's compensation  structure has historically been at
the low end of pharmaceutical companies with respect to salary and bonus payable
to its  executive officers  generally, and  to its  Chief Executive  Officer  in
particular.  The S&P Drugs Index, the  industry group included for comparison in
"Comparison of Five Year Cumulative Total Return Among ALZA, the S&P 500 and the
S&P Drugs  Index" set  forth below,  consists of  large national  pharmaceutical
companies  which have also  been used as  a reference in  setting ALZA executive
salaries.

    ALZA's compensation policies  take into account  ALZA's overall  performance
during   the  prior  year,  as  well   as  the  executive  officers'  individual
achievements and  contributions to  the company  during the  year. In  addition,
ALZA's compensation policies recognize the importance of stock ownership by, and
stock  option programs for,  senior executives, in order  to promote identity of
long-term interests between the executives and the stockholders of ALZA.

                                       7
<PAGE>
    In determining the compensation to be  paid to ALZA's executive officers  in
1993,   the  Committee   employed  compensation   policies  designed   to  align
compensation with  ALZA's  overall  business  strategy,  values  and  management
initiatives.  These policies are intended to (i) reward executives for long-term
strategic management and the  enhancement of stockholder  value; (ii) support  a
performance-oriented  environment that  rewards achievement  of internal company
objectives; (iii) recognize company  performance compared to performance  levels
of  comparable companies; and (iv) attract and retain executives whose abilities
are critical to the long-term success and competitiveness of ALZA. As a  result,
compensation  consists  of salary  and bonus  providing current  incentives, and
stock options providing longer term incentives.

    ALZA's performance  measurements  focus  on  both  financial  and  strategic
objectives.  During 1993, ALZA substantially achieved  the objectives set by its
Board of Directors, which included:

    - maintaining and expanding ALZA's technological leadership position in drug
      delivery;

    - expanding  ALZA's   product   development/royalty  business   with   other
      pharmaceutical companies;

    - establishing    the    infrastructure    for    ALZA's    planned   direct
      commercialization activities; and

    - obtaining significant royalties from existing client companies

all with the expected impact on  ALZA's financial objectives, while providing  a
highly  productive work  environment designed for  personal growth, intellectual
excitement and respect for all employees of the company.

    The key components of executive  officer compensation are (i) salary,  which
is based on factors such as the individual officer's level of responsibility for
meeting  the  company's financial  and  strategic objectives  and  comparison to
similar positions  in the  company  and comparable  companies; (ii)  cash  bonus
awards,  which are based on individual  performance and the performance of ALZA,
measured in terms of  attainment of ALZA's  financial and strategic  objectives;
and  (iii)  stock  option  grants  which are  intended  to  align  the executive
officers' interest in the company's long-term success with the interests of  the
company's  stockholders, as measured by changes over time in the company's stock
trading price.

    Stock options are an integral part of each executive officer's compensation.
The Committee  believes that  the opportunity  for stock  appreciation,  through
exercise  of stock options that vest over  time, closely aligns the interests of
the executive officers with ALZA's  stockholders. The size of individual  awards
take into account the executive officer's salary, number of unvested options and
past  contributions to the company.  No one factor is  given special weight, but
all are part of an overall assessment, with major emphasis being given to salary
levels.

    To the extent  ascertainable, the  Committee considers  the anticipated  tax
treatment  to ALZA and to its executives  of various payments and benefits. Some
types of  compensation  payments and  their  deductibility (eg,  the  spread  on
nonstatutory  stock  options) depend  on the  timing of  vesting or  exercise of
previously vested rights. Further interpretations  of and changes to  applicable
tax  laws  and other  factors  beyond the  Committee's  control also  affect the
deductibility of compensation. For  these and other  reasons, the Committee  may
not  in all cases limit executive compensation  to that deductible by ALZA under
Section 162  (m) of  the  Internal Revenue  Code.  The Committee  will  consider
various  alternatives to  preserving the deductibility  of compensation payments
and benefits to the extent reasonably  practicable and to the extent  consistent
with its other compensation policies and objectives.

RELATIONSHIP OF CORPORATE PERFORMANCE TO COMPENSATION PLANS

    The  executive officers'  compensation during  1993 comprised  the following
elements: (i)  base salary;  (ii)  bonuses based  on  a combination  of  overall
company  and  individual  performance during  the  year; (iii)  grants  of stock
options  (including  the  vesting  of  options  granted  in  prior  years);  and

                                       8
<PAGE>
(iv)  interest earned on  compensation deferred by  the executive officers under
ALZA's Executive Deferral Plans.  Both base compensation  and bonuses take  into
consideration  the achievement by ALZA of the financial and strategic objectives
described  above  in  "Compensation   Policies  Affecting  Executive   Officers"
established  by the Board of  Directors for the company  at the beginning of the
year, and the individual's contribution  toward achieving those objectives.  The
option  grants take  into account  the executives'  respective unvested options,
salary and contributions to the company.

OTHER COMPENSATION PLANS

    ALZA has adopted  certain broad-based  employee benefit plans  in which  the
executive officers may participate on the same basis as other employees who meet
eligibility  criteria, subject to legal limitations  on the benefits that may be
made available to an individual executive officer. During 1993, these plans that
involved  contributions  by  ALZA  included  an  Employee  Stock  Purchase  Plan
qualified  under  Section  423 of  the  Internal  Revenue Code,  under  which an
individual could elect to  purchase up to  $25,000 of ALZA's  Common Stock at  a
price equal to 85 percent of its fair market value, and the contribution for the
benefit  of each employee (including executive  officers) to the ALZA Retirement
Plan (a defined  contribution plan) of  an amount based  on the employee's  base
salary and age.

CHIEF EXECUTIVE OFFICER'S COMPENSATION

MARTIN S. GERSTEL

    The Committee based the 1993 compensation of Martin S. Gerstel, ALZA's Chief
Executive  Officer until August 1993, on the policies described above. In August
1993, the Committee approved  the grant to Mr.  Gerstel of a nonstatutory  stock
option  for 40,000  shares of  its Common  Stock, exercisable  at its  then fair
market value.  In making  this grant  to Mr.  Gerstel, the  Committee took  into
account  his  expected  continued  contribution  as  an  employee  of  ALZA, the
importance of his  assistance to ALZA's  new Chief Executive  Officer to make  a
smooth transition of responsibility, and his past contributions to ALZA.

    Mr.  Gerstel's  cash bonus  for  1993 was  primarily  in recognition  of Mr.
Gerstel's contribution to the  performance of ALZA  in achieving the  objectives
established  for 1993 by the Board of Directors at the beginning of the year and
described above in  "Compensation Policies Affecting  Executive Officers."  Also
considered  was his assistance to ALZA's  new Chief Executive Officer during the
transition period.  None  of  the  factors  included  in  ALZA's  strategic  and
financial  objectives  was  assigned  a  specific  weight.  Instead,  an overall
assessment of  Mr. Gerstel's  leadership in  achieving the  Company's  long-term
strategic  and financial objectives was utilized by the Committee in setting Mr.
Gerstel's compensation and bonus for 1993.

ERNEST MARIO

    In early 1992,  Mr. Gerstel  announced that he  would be  retiring as  Chief
Executive  Officer of ALZA. The company conducted  an extensive search for a new
Chief Executive  Officer and,  in  connection with  that search,  the  specially
formed Search Committee of the Board (the "Search Committee") reviewed carefully
the  available information  concerning the  compensation of  the chief executive
officers of regional  high technology companies  and of national  pharmaceutical
companies  generally, including those companies included in the S&P Drugs Index.
In addition, the  Search Committee reviewed  compensation of recently  appointed
chief  executive officers of similar sized  public companies. In connection with
these  activities,  the  Search  Committee  ascertained  that,  because   ALZA's
compensation structure is lower in comparison to other pharmaceutical companies,
it was likely that a compensation package for ALZA's new Chief Executive Officer
would require an increase in total compensation over that paid to Mr. Gerstel.

    In  early August 1993, Dr. Ernest  Mario became ALZA's Co-Chairman and Chief
Executive Officer. Dr. Mario  was identified as the  person who could best  lead
ALZA  in its goal of expanding  significantly the development, manufacturing and
marketing of its own  products, in addition to  continuing its client  business.
The  Search  Committee believed  that Dr.  Mario's  experience in  leading Glaxo
Holdings  plc,  as   its  Chief   Executive,  to  become   the  second   largest
pharmaceutical company in the world, was

                                       9
<PAGE>
uniquely  suited to  ALZA's needs. While  ALZA could not  provide a compensation
package comparable  to  Dr. Mario's  Glaxo  compensation, the  Search  Committee
believed that a base salary in the $500,000 range would be in line with salaries
of  chief  executive  officers  of  regional  publicly  traded  high  technology
companies, and broadly in line with ALZA's executive compensation structure. The
Committee believes that his salary is lower than that paid to most other  public
pharmaceutical  company chief  executive officers, and  significantly lower than
the salaries of the chief executive officers  of the companies in the S&P  Drugs
Index.

    Dr. Mario's bonus for 1993 is intended to reflect the significant activities
he  has  undertaken  on behalf  of  ALZA in  his  first five  months  with ALZA,
including the acceleration of the  development of ALZA's marketing  capabilities
and the achievement, on an accelerated basis, of several of the other objectives
described above.

    In  light  of  Dr. Mario's  significant  experience and  success,  the Board
determined that substantial long-term compensation, in the form of stock options
which would  appreciate  significantly  only with  a  corresponding  significant
increase  in stockholder values,  would be appropriate.  Dr. Mario was therefore
granted an  option  to purchase  750,000  shares of  ALZA  Common Stock  at  the
commencement of his employment with ALZA. The exercise price of these options is
the  fair market value on the  date of grant, and the  options vest in six equal
annual installments.  Because  of the  long  vesting schedule,  any  significant
compensation  arising from these options  will mirror corresponding increases in
stockholder values over that time period and, more importantly, will reflect Dr.
Mario's long-term contributions to the growth and success of ALZA.

                      COMPENSATION AND BENEFITS COMMITTEE

                        Robert J. Glaser, M.D., Chairman
                                 Dean O. Morton
                                  Isaac Stein

                                       10
<PAGE>
                           BENEFICIAL STOCK OWNERSHIP

    The  following table sets forth beneficial  ownership of ALZA's Common Stock
as of February 28, 1994,  (i) by each person, entity  or "groups" of persons  or
entities  known by ALZA to be beneficial owners of more than 5% of ALZA's Common
Stock, (ii) by  each director,  including nominees, and  each executive  officer
identified  in this Proxy Statement  under the heading "Executive Compensation,"
and (iii)  by  all  executive officers  and  directors  as a  group.  Except  as
described  below, each person has sole  investment and voting power with respect
to the Common Stock described in the table.

<TABLE>
<CAPTION>
                                AMOUNT AND NATURE
                                  OF BENEFICIAL     PERCENT
                                    OWNERSHIP          OF
NAME                                (1)(2)(3)       CLASS(4)
- ------------------------------  ------------------  --------
<S>                             <C>                 <C>
J.P. Morgan & Co. Incorporated
 23 Wall Street
 New York, NY(5)..............         8,548,865      10.47%
Ciba-Geigy Corporation
 444 Saw Mill River Rd.
 Ardsley, NY(6)...............         4,734,235       5.80%
William G. Davis..............            42,000      --
Adrian M. Gerber..............            40,000      --
Martin S. Gerstel(7)..........           243,428      --
Dr. Robert J. Glaser..........            14,884      --
Dr. Ernest Mario..............             5,000      --
Dean O. Morton................            14,000      --
Rudolph A. Peterson...........            46,163      --
Dr. Jane E. Shaw..............           291,535      --
Isaac Stein...................            19,608      --
Julian N. Stern(8)............           158,645      --
Dr. Felix Theeuwes............           213,132      --
Dr. Alejandro Zaffaroni.......           955,950       1.17%
All Executive Officers and
 Directors as a group (17
 persons).....................         2,111,452       2.59%
<FN>
- ------------------------
(1)   Includes outstanding  stock options  held by  such persons  to the  extent
      exercisable  on or before April 30,  1994 as follows: 40,000 option shares
      for Mr. Davis; 40,000 option shares  for Mr. Gerber; 50,000 option  shares
      for  Mr. Gerstel; 4,000 option shares  for Dr. Glaser; 4,000 option shares
      for Mr.  Morton; 13,000  option shares  for Mr.  Peterson; 116,000  option
      shares  for Dr.  Shaw; 8,000  option shares  for Mr.  Stein; 44,000 option
      shares for Mr. Stern; 32,000 option  shares for Dr. Theeuwes; and  385,200
      option shares for all executive officers and directors as a group.
(2)   Includes  shares allocated to such persons' accounts under ALZA's Employee
      Stock Ownership Plan and Tax  Deferral Investment Plan as follows:  91,110
      shares  for  Mr. Gerstel,  116,099 shares  for Dr.  Shaw (of  which 43,844
      shares are allocated to accounts for Dr. Shaw's spouse, a former  employee
      of  ALZA, under such  plans); 66,196 shares for  Dr. Theeuwes, and 274,947
      shares for all  executive officers  and directors  as a  group. Under  the
      Employee  Stock Ownership Plan, such persons  have voting power as to such
      securities and,  after attaining  the age  of 55,  have limited  power  to
      direct  the  disposition  of  such  securities.  Under  the  Tax  Deferral
      Investment Plan, such persons have both voting and dispositive power  with
      respect to such securities.
(3)   Excludes   shares  covered  by  outstanding  warrants,  each  to  purchase
      one-eighth of one  share of  Common Stock  at a  price of  $65 per  share,
      exercisable  at any time commencing June 11, 1996 and expiring on December
      31, 1999  (the  "Warrants").  Also excludes  Warrants  allocated  to  such
      persons'  accounts  under ALZA's  Employee  Stock Ownership  Plan  and Tax
      Deferrel Investment Plan.
(4)   Percentages are  not  shown  if  holdings total  less  than  1%  of  total
      outstanding shares.
</TABLE>

                                       11
<PAGE>
<TABLE>
<S>   <C>
(5)   Information  is  as of  December 31,  1993  as provided  by the  holder in
      Amendment No. 7 to its Schedule 13G dated December 31, 1993 and filed with
      the Securities and Exchange Commission. As to such shares, the holder  has
      provided the following information; sole voting power -- 4,028,560 shares;
      shared voting power -- 290,100 shares; sole dispositive power -- 8,205,015
      shares; shared dispositive power -- 336,050 shares.
(6)   Information  is as of December  31, 1993 as provided  by the holder. As to
      such  shares,  2,754,820  shares  are  owned  by  Ciba-Geigy   Corporation
      ("Ciba-Geigy")  and held in  escrow under an Escrow  Agreement dated as of
      March 15, 1991 between Ciba-Geigy and  Chemical Bank, as Escrow Agent,  to
      provide for the exchange of Exchangeable Subordinated Debentures issued by
      Ciba-Geigy.
(7)   Includes  10,908 shares held by Mr. Gerstel  as trustee for the benefit of
      an unrelated person.
(8)   Includes 6,966 shares held by Mr. Stern  as trustee for the benefit of  an
      unrelated person.
</TABLE>

                                       12
<PAGE>
                COMPARISON OF FIVE YEAR CUMULATIVE TOTAL RETURN
                    AMONG ALZA, S&P DRUGS INDEX AND S&P 500

    Note: Set  forth below  is a tabular  presentation of  the performance graph
          which appears in the Proxy Statement distributed to stockholders. Also
          set  forth  below  are   explanatory  paragraphs  which  precede   the
          performance graph.

EXPLANATORY PARAGRAPHS PRECEDING THE PERFORMANCE GRAPH:

    The  rules  of  the Securities  and  Exchange Commission  require  that ALZA
include in this Proxy Statement  a line-graph presentation comparing  cumulative
five-year  stockholder returns on  an indexed basis  with the S&P  500 Index and
either a  nationally recognized  industry standard  index or  an index  of  peer
companies  selected by  ALZA. ALZA has  elected to  use the S&P  Drugs Index for
purpose of  the performance  comparison which  appears below.  There can  be  no
assurance  that ALZA's stock performance will  continue into the future with the
same or similar trends depicted below.

    The graph below has been prepared to give effect to the distribution to ALZA
stockholders on June 11,  1993 of units (the  "Units"), each Unit consisting  of
one  share of Class A Common Stock  of Therapeutic Discovery Corporation and one
warrant to purchase one-eighth of one share of Common Stock of ALZA. Each holder
of Common Stock of ALZA received one  Unit for every ten shares of Common  Stock
held  on May  28, 1993, the  record date  for the distribution.  The graph below
assumes that the one-tenth of one Unit received in respect of one share of  ALZA
Common  Stock was sold on  the distribution date (June  11, 1993) at the closing
sale price  of  the  Units  on  such  date  ($6.25)  and  the  proceeds  thereof
immediately applied toward the purchase of 0.0239 shares of ALZA Common Stock at
a  price based  on the  closing sales  price of  the Common  Stock on  such date
($26.125).

TABULAR PRESENTATION OF PERFORMANCE GRAPH:

<TABLE>
<CAPTION>
                                               1988       1989       1990       1991       1992       1993
                                             ---------  ---------  ---------  ---------  ---------  ---------
<S>                                          <C>        <C>        <C>        <C>        <C>        <C>
ALZA                                            100.00     196.00     227.00     439.00     420.00     258.55
S&P Drugs                                       100.00     149.75     171.17     282.06     226.10     206.22
S&P 500                                         100.00     131.69     127.61     166.49     179.18     197.06
<FN>
- ------------------------
The  S&P  Drugs  Index  includes  the  following:  Eli  Lilly,  Merck,   Pfizer,
Schering-Plough, Syntex and Upjohn.
</TABLE>

                                       13
<PAGE>
                              CERTAIN TRANSACTIONS

    In June 1990, ALZA made a loan in the amount of $80,000 to Adrian M. Gerber,
Executive Vice President of ALZA, in connection with his offer of employment and
relocation  to California. This loan was refinanced  by ALZA on August 15, 1993.
The loan bears interest at the rate of 3.62% per annum and is payable in full on
or before August 15, 1996. At  December 31, 1993, the outstanding principal  and
accrued  interest on  the loan  totalled $106,072.93.  Repayment of  the loan is
secured by a second deed of trust on Mr. Gerber's residence.

    In December 1993,  ALZA made  a loan  in the amount  of $64,680  to Gary  S.
Lyman,  Vice  President,  Manufacturing,  in  connection  with  his  exercise of
warrants to purchase Common Stock of ALZA.  The loan bears interest at the  rate
of  5% per annum and is payable in full  on or before May 31, 1994. Repayment of
the loan is secured by shares of ALZA Common Stock.

    ALZA and Affymax N.V. ("Affymax") have entered into a partnership  agreement
for  joint development and commercialization of products incorporating compounds
modified by  Affymax  and  ALZA's  electrotransport  technology.  Dr.  Alejandro
Zaffaroni,  Dr.  Robert  J.  Glaser  and  Mr.  Julian  N.  Stern,  directors and
stockholders of ALZA, are directors and shareholders of Affymax. The  definitive
agreement  with Affymax was approved by a  majority of the directors of ALZA who
are not also directors of Affymax.

                      RATIFICATION OF INDEPENDENT AUDITORS

    The Board recommends that the stockholders ratify the appointment of Ernst &
Young as independent auditors to audit the financial statements of ALZA for  the
year  ending December 31, 1994. Ernst &  Young (and its predecessor company) has
acted as ALZA's  auditor since  ALZA's inception.  A representative  of Ernst  &
Young  will be present at the Annual Meeting, will have an opportunity to make a
statement if he or  she desires to do  so, and will be  available to respond  to
appropriate  questions. A favorable vote of a majority of the shares present and
voting at the Annual Meeting  is required to ratify  the appointment of Ernst  &
Young.

                         ANNUAL REPORT TO STOCKHOLDERS

    ALZA's  Annual Report to  Stockholders for the year  ended December 31, 1993
containing the audited consolidated balance sheets  as of December 31, 1993  and
1992 and the related consolidated statements of operations, stockholders' equity
and  cash flows for  each of the past  three fiscal years,  is being mailed with
this Proxy Statement to stockholders entitled to notice of the Annual Meeting.

                             STOCKHOLDER PROPOSALS

    ALZA will,  in future  proxy statements  of the  Board, include  stockholder
proposals  complying with  the applicable rules  of the  Securities and Exchange
Commission and  the procedures  set forth  in  ALZA's by-laws.  In order  for  a
proposal  by a stockholder  to be included  in the proxy  statement of the Board
relating to the annual meeting of stockholders to be held in the spring of 1995,
that proposal must be received in writing by the Secretary of ALZA no later than
November 15, 1994.

                                       14
<PAGE>
                                 OTHER MATTERS

    The Board knows of  no other matters  that will be  presented at the  Annual
Meeting.  If, however, any  matter is properly presented  at the Annual Meeting,
the proxy solicited hereby will be voted in accordance with the judgment of  the
proxy holders.

                                          By Order of the Board of Directors,

                                                JULIAN N. STERN
                                                   Secretary
Palo Alto, California
March 14, 1994

     YOU  ARE CORDIALLY INVITED TO ATTEND THE ANNUAL MEETING IN PERSON. WHETHER
 OR NOT YOU PLAN TO  ATTEND THE MEETING, YOU ARE  REQUESTED TO SIGN AND  RETURN
 THE  ACCOMPANYING PROXY CARD AS SOON  AS POSSIBLE IN THE ACCOMPANYING POSTPAID
 ENVELOPE. YOUR DOING SO MAY SAVE ALZA THE EXPENSE OF A SECOND MAILING.

                                       15
<PAGE>

                               PROXY

                          ALZA CORPORATION

        THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

   The undersigned hereby appoint(s) ERNEST MARIO, JANE E. SHAW and
BRUCE C. COZADD, or any of them, each with full power of substitution,
the lawful attorneys and proxies of the undersigned to vote, as designated
on the reverse side of this proxy card, all of the shares of ALZA
CORPORATION which the undersigned shall be entitled to vote at the
Annual Meeting of Stockholders to be held on April 26, 1994 and at
any adjournments and postponements thereof.

This proxy, when properly executed, will be voted in the manner directed
by the undersigned stockholder(s). This proxy may be revoked at any time
prior to the time it is voted by any means described in the accompanying
Proxy Statement.

                             Continued and to be signed on the reverse side
                                                           See reverse side

<PAGE>

THE BOARD OF DIRECTORS OF ALZA CORPORATION UNANIMOUSLY RECOMMENDS A VOTE
FOR ALL OF THE FOLLOWING PROPOSALS:

1.  To elect as Class I directors:       Nominees:

                                         William G. Davis
                                         Martin S. Gerstel
                                         Julian N. Stern

FOR                WITHHOLD              (To withhold authority to vote for any
                                         individual Class I nominee, write that
   / /               / /                 nominee's name in the space provided
                                         below.)

                                         _____________________________________
                                         For all nominees except as noted above

2.  To ratify the appointment of Ernst   3.  In their discretion to vote upon
    & Young as ALZA's independent             such other business as may
    public auditors for the fiscal year       properly be presented at the
    ended December 31, 1994.                  meeting.

    FOR    AGAINST   ABSTAIN

    / /      / /      / /
                                         Please date and sign exactly as
                                         name(s) appear(s) herein. If shares
                                         are held jointly, each holder should
                                         sign. Please give full title and
                                         capacity in which signing if not
                                         signing as an individual stockholder.

                                         Signature_________________Date_________

                                         Signature_________________Date_________

WHEN NO CHOICE IS INDICATED, THIS PROXY
WILL BE VOTED FOR EACH OF THE ABOVE
PROPOSALS.



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