ALZA CORP
DEF 14A, 1996-04-01
PHARMACEUTICAL PREPARATIONS
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<PAGE>
                            SCHEDULE 14A INFORMATION
 
                  Proxy Statement Pursuant to Section 14(a) of
            the Securities Exchange Act of 1934 (Amendment No.    )
 
    Filed by the Registrant /X/
    Filed by a Party other than the Registrant / /
 
    Check the appropriate box:
    / /  Preliminary Proxy Statement
    / /  Confidential, for Use of the Commission Only (as permitted by Rule
         14a-6(e)(2))
    /X/  Definitive Proxy Statement
    / /  Definitive Additional Materials
    / /  Soliciting  Material  Pursuant  to  Section  240.14a-11(c)  or  Section
         240.14a-12
 
                                          ALZA CORPORATION
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)
 
- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)
 
Payment of Filing Fee (Check the appropriate box):
 
/X/  $125 per  Exchange Act  Rules 0-11(c)(1)(ii),  14a-6(i)(1), 14a-6(i)(2)  or
     Item 22(a)(2) of Schedule 14A.
/ /  $500  per  each party  to  the controversy  pursuant  to Exchange  Act Rule
     14a-6(i)(3).
/ /  Fee  computed  on   table  below   per  Exchange   Act  Rules   14a-6(i)(4)
     and 0-11.
     1) Title of each class of securities to which transaction applies:
        ------------------------------------------------------------------------
     2) Aggregate number of securities to which transaction applies:
        ------------------------------------------------------------------------
     3) Per unit price or other underlying value of transaction computed
        pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the
        filing fee is calculated and state how it was determined):
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     4) Proposed maximum aggregate value of transaction:
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     5) Total fee paid:
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/ /  Fee paid previously with preliminary materials.
/ /  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2)  and identify the  filing for which the  offsetting fee was paid
     previously. Identify the previous filing by registration statement  number,
     or the Form or Schedule and the date of its filing.
     1) Amount Previously Paid:
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     4) Date Filed:
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<PAGE>
                                   [ALZA LOGO]
                                ALZA CORPORATION
                               ------------------
 
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                       TO BE HELD MAY 23, 1996 AT 1:00 PM
 
To the Stockholders of ALZA Corporation:
 
    NOTICE  IS  HEREBY GIVEN  that the  Annual Meeting  of Stockholders  of ALZA
Corporation will  be held  at 950  Page  Mill Road,  Palo Alto,  California,  on
Thursday, May 23, 1996 at 1:00 pm, for the following purposes:
 
    1.   To elect three Class III directors  to hold office for a term ending in
       1999 and until their successors are elected;
 
    2.  To  consider and act  upon a  stockholder proposal if  presented at  the
       meeting;
 
    3.   To ratify  the appointment of  Ernst & Young  LLP as ALZA's independent
       auditors for the fiscal year ended December 31, 1996; and
 
    4.  To  transact such other  business as  may properly be  presented at  the
       meeting and at any adjournments or postponements thereof.
 
    Only  holders of record of  ALZA's Common Stock at  the close of business on
March 25, 1996 are entitled  to notice of, and to  vote at, the meeting and  any
adjournments or postponements thereof.
 
                                          By Order of the Board of Directors,
 
                                          JULIAN N. STERN
                                          SECRETARY
Palo Alto, California
April 1, 1996
 
WHETHER  OR  NOT  YOU  PLAN  TO  ATTEND  THE  ANNUAL  MEETING,  PLEASE  SIGN THE
ACCOMPANYING PROXY CARD AND  RETURN IT AS SOON  AS POSSIBLE IN THE  ACCOMPANYING
POSTPAID ENVELOPE. YOUR DOING SO MAY SAVE ALZA THE EXPENSE OF A SECOND MAILING.
<PAGE>
                                ALZA CORPORATION
                                PROXY STATEMENT
                             ---------------------
 
To the Stockholders of ALZA Corporation:
 
    The accompanying proxy is solicited on behalf of the Board of Directors (the
"Board")  of ALZA Corporation ("ALZA" or the "Company"), a Delaware corporation,
for use at ALZA's 1996 Annual Meeting of Stockholders (the "Annual Meeting")  to
be  held at 1:00 pm on Thursday, May  23, 1996 at ALZA's headquarters located at
950 Page  Mill  Road,  Palo  Alto,  California  94304;  telephone  number  (415)
494-5000.
 
    Only holders of record of ALZA's Common Stock as of the close of business on
March 25, 1996 are entitled to notice of, and to vote at, the Annual Meeting and
any  adjournments or  postponements thereof.  At the  close of  business on that
date, ALZA had outstanding 84,147,560 shares of its Common Stock, par value $.01
per share. Holders of Common  Stock are entitled to one  vote for each share  of
Common Stock held.
 
    Any  holder of  Common Stock  giving a proxy  in the  form accompanying this
Proxy Statement has the power to revoke the proxy prior to its use. A proxy  can
be  revoked (i)  by an  instrument of revocation  delivered prior  to the Annual
Meeting to the Secretary of ALZA, (ii) by a duly executed proxy bearing a  later
date  or time than the date or time of  the proxy being revoked, or (iii) at the
Annual Meeting if the stockholder is present and elects to vote in person.  Mere
attendance at the Annual Meeting will not serve to revoke a proxy.
 
    Broker  non-votes, and shares  held by stockholders present  in person or by
proxy at the meeting but  abstaining on a vote,  will be counted in  determining
whether  a  quorum is  present at  the Annual  Meeting. However,  abstentions by
stockholders present in person or by proxy  at the meeting are counted as  votes
against  a proposal for  purposes of determining  whether or not  a proposal has
been approved,  whereas  broker  non-votes  are  not  counted  for  purposes  of
determining whether a proposal has been approved.
 
    This  Proxy Statement  and the accompanying  proxy card are  being mailed to
ALZA stockholders  on or  about April  1, 1996.  Directors, officers  and  other
employees  of  ALZA  may solicit  proxies  by personal  interview,  telephone or
facsimile, without special compensation. Any costs of such solicitation will  be
borne by ALZA.
 
                             ELECTION OF DIRECTORS
 
    ALZA's Certificate of Incorporation provides for three classes of directors:
Class  I, Class II and Class III. Only one class of directors is elected at each
annual meeting of stockholders, each director to serve for a three-year term. In
accordance with the Certificate of Incorporation, Class III directors are to  be
elected  at the 1996 annual meeting, Class I  directors are to be elected at the
1997 annual meeting and Class II directors are to be elected at the 1998  annual
meeting.
 
NOMINEES
 
    There currently are four Class III directors, three of whom will be standing
for  re-election.  Mr. Rudolph  Peterson,  a director  of  ALZA since  1969, has
decided to retire from active status as a director, effective as of the date  of
the  Annual Meeting. Mr. Peterson  will continue to provide  advice to the Board
from time to time as  a consultant. Mr. Martin Gerstel,  a Class I director  and
ALZA's  former Chief Executive  Officer, has also decided  to retire from active
status as  a director,  effective as  of the  date of  the Annual  Meeting.  Mr.
Gerstel  will  continue as  a part-time  employee  of ALZA,  undertaking special
projects as  requested  by the  Chief  Executive Officer.  As  a result  of  the
retirement  of  Mr. Gerstel  and Mr.  Peterson,  ALZA's Nominating  Committee is
actively engaged  in  efforts  to  identify  and  recruit  additional  qualified
directors for the Company.
 
                                       1
<PAGE>
    On  February 15, 1996, the Board of  Directors voted to amend ALZA's Bylaws,
effective as  of the  date of  the Annual  Meeting, to  decrease the  number  of
directors  constituting the  Board from nine  to seven directors  to reflect the
retirement of Messrs. Gerstel and Peterson. As a result of this amendment, three
Class III directors are to be elected  to the Board at the Annual Meeting,  each
to  serve until the annual meeting of stockholders  to be held in 1999 and until
his successor  has been  elected  and qualified,  or  until his  earlier  death,
resignation  or removal. The nominees for election at the Annual Meeting are Dr.
Ernest Mario, Mr. Isaac Stein and Dr. Alejandro Zaffaroni.
 
    Each of the  nominees presently is  a director  of ALZA. If  any nominee  is
unable  or  unwilling  to  serve as  a  director,  proxies may  be  voted  for a
substitute nominee designated by the present  Board. The Board has no reason  to
believe  that any nominee will be unable or  unwilling to serve as a director if
elected. Proxies  received will  be voted  "FOR" the  election of  all  nominees
unless  marked to the contrary. Pursuant to applicable Delaware corporation law,
assuming the presence of  a quorum, three directors  will be elected from  among
those  persons duly  nominated for  such positions by  a plurality  of the votes
actually cast by stockholders entitled to vote at the meeting who are present in
person or  by proxy.  Thus, nominees  who receive  the first,  second and  third
highest  number of votes in favor of  their election will be elected, regardless
of the number of abstentions or broker non-votes.
 
    The following  table provides  the names  of the  nominees for  election  as
directors  and each other  director and indicates the  periods during which such
persons have served as directors of ALZA.
 
<TABLE>
<CAPTION>
                                                                                               DIRECTOR
                                                                                             CONTINUOUSLY
NAME AND POSITIONS WITH ALZA IN ADDITION TO DIRECTOR                                             SINCE
- ------------------------------------------------------------------------------------------  ---------------
<S>                                                                                         <C>
NOMINEES (CLASS III DIRECTORS)
 
Dr. Ernest Mario..........................................................................          1993
  Co-Chairman and Chief Executive Officer
Isaac Stein...............................................................................          1987
Dr. Alejandro Zaffaroni...................................................................          1968
  Co-Chairman and Founder
 
INCUMBENTS
 
CLASS I DIRECTORS
William G. Davis..........................................................................          1989
Julian N. Stern...........................................................................          1982
  Secretary
 
CLASS II DIRECTORS
Dr. Robert J. Glaser......................................................................          1987
Dean O. Morton............................................................................          1987
 
RETIRING DIRECTORS
Martin S. Gerstel.........................................................................          1980
Rudolph A. Peterson.......................................................................          1969
</TABLE>
 
BUSINESS EXPERIENCE OF DIRECTORS
 
    NOMINEES (CLASS III DIRECTORS)
 
    Dr. Ernest Mario,  57, is  the Co-Chairman  and Chief  Executive Officer  of
ALZA.  Prior  to joining  ALZA, Dr.  Mario  served as  Chief Executive  of Glaxo
Holdings plc, a pharmaceutical corporation, from May 1989 to March 1993, and  as
Deputy  Chairman from January 1992 to March  1993. Prior to that time, Dr. Mario
served as Chairman and Chief Executive  Officer of Glaxo, Inc., a subsidiary  of
Glaxo  Holdings, from 1988 to 1989 and  as President and Chief Operating Officer
of Glaxo, Inc., from 1986  to 1988. Prior to joining  Glaxo, Dr. Mario had  held
various executive positions at Squibb Corporation and
 
                                       2
<PAGE>
served  as a  director of  that company.  Dr. Mario  is also  a director  of COR
Therapeutics,  Inc.,  a  biotechnology   company,  and  Pharmaceutical   Product
Development, Inc., a contract clinical research organization.
 
    Isaac  Stein, 49, has been President of Waverley Associates, Inc., a private
investment firm, since 1983. Mr. Stein served as Chairman of the Board of Esprit
de Corp from  June 1990 to  December 1992. Mr.  Stein is also  a trustee of  the
Benham Group of Mutual Funds and a director of Raychem Corporation.
 
    Dr.  Alejandro Zaffaroni, 73, the founder of  ALZA, has been Chairman of the
Board of  ALZA  since 1982  and  Co-Chairman since  1987.  He was  ALZA's  Chief
Executive  Officer  from 1968  until 1987.  He  was President  of ALZA  from its
inception in 1968 until 1982.  From 1988 to March  1995, Dr. Zaffaroni was  also
the  Chairman  and Chief  Executive Officer  of Affymax  N.V., a  drug discovery
company. He currently spends 50% of his time on the affairs of ALZA.
 
    INCUMBENTS
 
    CLASS I DIRECTORS
 
    William G. Davis, 64,  is an independent business  consultant. Prior to  his
retirement  from Eli  Lilly &  Company in  1984, Mr.  Davis held  various senior
executive positions during his 27-year tenure with that company. Mr. Davis is  a
director   of   Collagen   Corporation,   Endosonics   Corporation   and  Target
Therapeutics, Inc.
 
    Julian N. Stern, 71, has been Secretary  of ALZA since 1968. He is the  sole
employee  of a  professional corporation  that is  a member  of the  law firm of
Heller, Ehrman, White & McAuliffe.
 
    CLASS II DIRECTORS
 
    Dr. Robert J. Glaser, 77, has been  the Director for Medical Science of  the
Lucille  P. Markey Charitable Trust, a philanthropic foundation supporting basic
biomedical research, since 1984, and a trustee since 1988. Prior to that time he
was President, Chief  Executive Officer  and a trustee  of the  Henry J.  Kaiser
Family  Foundation.  Dr.  Glaser  is  a  director  of  Nellcor  Puritan  Bennett
Incorporated and Hanger Orthopedic Group, Inc. In 1991, Dr. Glaser retired as  a
director of Hewlett-Packard Company after serving since 1971.
 
    Dean  O. Morton,  64, retired in  October 1992 as  Executive Vice President,
Chief Operating Officer and a director of Hewlett-Packard Company, where he held
various positions since 1960. Mr. Morton  is a director of Raychem  Corporation,
The Clorox Company, Centigram Communications Corporation and Tencor Instruments.
He  is a trustee of the Metropolitan  Series Funds, Metlife Portfolios and State
Street Research Funds.
 
    RETIRING DIRECTORS
 
    Rudolph A.  Peterson,  91, is  the  President and  Chief  Executive  Officer
(retired)  and  honorary director  of Bank  of America  Corporation and  Bank of
America N.T.  & S.A.  and  the Administrator  (retired)  of the  United  Nations
Development Programme.
 
    Martin  S. Gerstel,  54, retired  in August  1993 as  ALZA's Co-Chairman and
Chief Executive  Officer, having  served in  such capacity  since 1987,  and  as
ALZA's  Chief Financial Officer, having served  in such capacity since 1968. Mr.
Gerstel served as ALZA's President from 1982 until 1987 and its Chief  Operating
Officer  from 1980  to 1987.  Mr. Gerstel is  a director  of TEVA Pharmaceutical
Industries of Israel.
 
MEETINGS AND COMMITTEES OF THE BOARD
 
    There were five  meetings of the  full Board during  fiscal 1995. The  Board
currently   has  three  standing  committees,   the  Compensation  and  Benefits
Committee, the Finance  and Audit  Committee and the  Nominating Committee.  The
current  members  of  the Compensation  and  Benefits Committee  are  Dr. Glaser
(Chairman)  and  Messrs.  Morton  and  Stein.  The  Compensation  and   Benefits
Committee,  which  met six  times  during fiscal  1995,  approves all  of ALZA's
compensation plans, including the
 
                                       3
<PAGE>
awarding of options under  ALZA's stock plan  and the compensation  arrangements
for  ALZA's senior management.  The Finance and Audit  Committee, which met five
times during fiscal 1995, consults  with ALZA's independent auditors  concerning
their  auditing  plan,  the  results  of  their  audit,  the  appropriateness of
accounting principles used by ALZA and the adequacy of ALZA's general accounting
controls. The current  members of the  Finance and Audit  Committee are  Messrs.
Morton (Chairman), Peterson (retiring), Stern, Davis and Stein.
 
    In  1995, the Board  appointed a Nominating Committee,  the members of which
are Messrs. Stein (Chairman),  Davis and Morton and  Dr. Glaser. The  Nominating
Committee,  which  met  two times  during  fiscal 1995,  searches  for qualified
persons to serve  as directors  of the  Company. As  a result  of the  announced
retirement  of  Messrs.  Peterson  and  Gerstel,  the  Nominating  Committee  is
increasing its efforts to identify  and recruit additional qualified  directors.
ALZA's  Bylaws provide that stockholders may nominate candidates for election as
directors by delivery of written notice to ALZA's Secretary at least sixty  days
in  advance of the stockholders' meeting or ten days after notice of the meeting
is first given  to stockholders, whichever  is later. Any  such notice must  set
forth  the name and address  of the nominating stockholder  and the nominee, and
such information concerning both such persons as would be required by the  rules
and  regulations of the Securities  and Exchange Commission to  be included in a
proxy statement soliciting proxies for the  election of the nominee. The  notice
must  be  accompanied  by the  written  consent of  the  nominee to  serve  as a
director, if elected.
 
    During 1995, each director attended at least 75% of the meetings of the full
Board and the committees of the Board on which he served.
 
    Each director who is not an employee of ALZA receives an annual retainer fee
of $20,000 plus  $1,000 for  each meeting  day of the  Board and  $750 for  each
regular  meeting of  any standing  committee, or  other committee  formed by the
Board from time to time, on which the director serves and $500 for each  special
meeting  of any committee on  which the director serves  (except for chairmen of
the committees, who  receive $1,250  for each  meeting day  of their  respective
committees).  In addition, each director who is not an employee of ALZA receives
a fee of $350 for each teleconference  meeting of the Board or of any  committee
lasting  more  than one  hour.  ALZA's Secretary  receives  a fee  for attending
meetings of the Compensation and Benefits Committee equal to the fee paid to the
directors who serve  on that  committee. ALZA's  non-employee directors  receive
options  to purchase Common Stock pursuant  to the automatic grant provisions of
ALZA's Amended and Restated Stock Plan.
 
                                       4
<PAGE>
                             EXECUTIVE COMPENSATION
                           SUMMARY COMPENSATION TABLE
 
    The following table sets forth certain information relating to  compensation
paid or accrued for services in all capacities during the fiscal years indicated
with  respect to Dr. Ernest  Mario, ALZA's Chief Executive  Officer, and each of
ALZA's other four most highly compensated executive officers who were serving as
executive officers as of December 31, 1995 (the "Named Executive Officers").
 
<TABLE>
<CAPTION>
                                                                                              LONG-TERM
                                                                                            COMPENSATION
                                                           ANNUAL COMPENSATION                 AWARDS
                                               -------------------------------------------  -------------
                                                                               OTHER         SECURITIES
                                                                               ANNUAL        UNDERLYING       ALL OTHER
NAME AND PRINCIPAL POSITIONS          YEAR     SALARY (1)   BONUS (1)(2)  COMPENSATION (3)   OPTIONS (4)   COMPENSATION (5)
- ----------------------------------  ---------  -----------  ------------  ----------------  -------------  ----------------
<S>                                 <C>        <C>          <C>           <C>               <C>            <C>
Dr. Ernest Mario (6)..............       1995  $   570,840   $  100,000      $   --               75,000     $     62,825
 Co-Chairman and                         1994      541,667       --              68,316           75,000           31,864
 Chief Executive Officer                 1993      250,000       25,000          --              750,000            6,063
Dr. Alejandro Zaffaroni (6).......       1995      252,756       50,000          --              --               209,969
 Co-Chairman                             1994      245,835       --              --              --               177,284
 and Founder                             1993      222,917       15,000          --              --               148,695
Dr. Felix Theeuwes................       1995      331,680       70,000          --               60,000           96,487
 President, Research                     1994      287,498       30,000          --               75,000           80,337
 and Development                         1993      246,834       20,000          --               25,000           85,335
 Chief Scientist
Dr. Samuel R. Saks................       1995      291,674       70,000          --               45,000            6,360
 Senior Vice President,                  1994      260,334       40,000          --               60,000            5,905
 Medical Affairs
Peter D. Staple (6)...............       1995      232,500       50,000          91,643           40,000            8,165
 Vice President and                      1994      184,461       25,000           5,000           60,000          --
 General Counsel
</TABLE>
 
- ------------------------
(1) Amounts  shown  include  compensation  earned  and  received  by  the  Named
    Executive  Officers  as well  as amounts  deferred at  the election  of such
    persons under ALZA's  Executive Deferral Plans  and Tax Deferral  Investment
    Plan.
 
(2) Bonuses  consist of  amounts paid  under ALZA's  PACE bonus  program (or the
    predecessor Executive Incentive Plan, which has been discontinued).
 
(3) Amount shown for Dr. Mario consists of relocation expenses incurred and paid
    in 1994.  Amount  shown  for Mr.  Staple  in  1995 consists  of  $78,156  of
    relocation  expenses reimbursed and $13,487 of mortgage differential paid in
    1995. Amount  shown for  Mr. Staple  in  1994 consists  of amounts  paid  in
    connection with the commencement of his employment with ALZA.
 
(4) The  options were granted for a term  of ten years. All unvested options are
    subject to  earlier  termination in  the  event  of the  termination  of  an
    employee's  relationship with ALZA. Of the options granted to Dr. Mario, one
    option for 75,000 shares is fully exercisable on August 10, 1998, the  other
    option  for 75,000 shares is fully exercisable  on November 29, 1997 and the
    option for 750,000 shares  is exercisable in  six equal annual  installments
    commencing  on August 10, 1994.  Of the options granted  to Dr. Theeuwes, an
    option for 30,000 shares is fully  exercisable on October 13, 1998,  another
    option for 30,000 shares is fully exercisable on August 10, 1998, the option
    for  75,000 shares is fully  exercisable on June 6,  1997 and the option for
    25,000 shares  is fully  exercisable  on August  10,  1996. Of  the  options
    granted  to Dr. Saks,  an option for  20,000 shares is  fully exercisable on
    October 13, 1998, an option for 25,000 shares is fully exercisable on August
    10, 1998 and the option  for 60,000 shares is  fully exercisable on June  6,
    1997.  Of the options granted to Mr.  Staple, an option for 30,000 shares is
    fully exercisable on October 13, 1998, an option for 10,000 shares is  fully
    exercisable  on August 10,  1998 and the  option for 60,000  shares is fully
    exercisable in three  equal annual  installments commencing  on February  9,
    1995. All options
 
                                       5
<PAGE>
    were  granted at fair market  value on the date of  grant. In the event that
    certain change  in control  events were  to occur,  all such  options  would
    become  immediately  exercisable,  except options  granted  in  October 1995
    (which become exercisable in October 1998), which options generally  provide
    for  acceleration of vesting only if the option holder's employment with the
    Company is terminated  (other than  for "cause")  within two  years after  a
    change of control. The option exercise price may be paid, subject to certain
    conditions,  by delivery of  already owned shares or  with the proceeds from
    the sale of the  option shares. The tax  withholding obligations related  to
    the  exercise may  be paid,  subject to  certain conditions,  by delivery of
    already-owned shares or by  offset of the shares  issuable upon exercise  of
    the  option. Under the terms of ALZA's  Amended and Restated Stock Plan, the
    Compensation and  Benefits Committee  retains  discretion, subject  to  plan
    limits,  to reprice options and to otherwise modify the terms (including the
    exercise price and vesting dates) of outstanding options.
 
(5) Amounts shown for the  fiscal year ended December  31, 1995 consist of:  (i)
    amounts  contributed  by  ALZA  to  the  employees'  accounts  under  ALZA's
    Retirement Plan as follows:  $16,227 for Dr. Theeuwes,  $6,293 for Dr.  Saks
    and  $7,709 for Mr. Staple, and (ii) amounts representing interest in excess
    of 120% of the applicable federal long-term rate on amounts deferred at  the
    election  of the  participants under  ALZA's Executive  Deferral Plans. Such
    reportable interest for 1995 totaled $62,825 for Dr. Mario, $209,969 for Dr.
    Zaffaroni, $80,260  for Dr.  Theeuwes, $67  for Dr.  Saks and  $456 for  Mr.
    Staple.
 
(6) Dr.  Mario joined ALZA in August 1993. Mr. Staple joined ALZA in March 1994.
    Dr. Zaffaroni devoted  50% of his  time to  the affairs of  ALZA during  the
    years shown.
 
                               1995 OPTION GRANTS
 
    The  following table sets  forth information relating  to options granted in
1995 to the Named Executive Officers. In addition, in accordance with the  rules
of  the Securities and  Exchange Commission, the  table shows hypothetical gains
that would exist  for such  options based on  assumed rates  of annual  compound
stock  price appreciation of 0%,  5% and 10% per year  from the date the options
were granted over the full option term.
 
<TABLE>
<CAPTION>
                                                       INDIVIDUAL GRANTS                      POTENTIAL REALIZABLE VALUE AT
                                     -----------------------------------------------------    ASSUMED ANNUAL RATES OF STOCK
                                      NUMBER OF     PERCENT OF                                PRICE APPRECIATION FOR OPTION
                                     SECURITIES    TOTAL OPTIONS                                        TERM (1)
                                     UNDERLYING     GRANTED TO      EXERCISE                 -------------------------------
                                       OPTIONS     EMPLOYEES IN    PRICE PER    EXPIRATION   0% PER     5% PER     10% PER
NAME                                 GRANTED (2)    FISCAL YEAR    SHARE (3)       DATE       YEAR       YEAR        YEAR
- -----------------------------------  -----------   -------------   ----------   ----------   ------   ----------  ----------
<S>                                  <C>           <C>             <C>          <C>          <C>      <C>         <C>
Dr. Ernest Mario...................    75,000          4.16%         $24.75        8/10/05    --      $1,167,750  $2,958,750
Dr. Alejandro Zaffaroni............     --            --              --            --        --          --          --
Dr. Felix Theeuwes.................    30,000          3.33           24.75        8/10/05    --         467,100   1,183,500
                                       30,000                         23.00       10/13/05    --         433,800   1,099,800
Dr. Samuel R. Saks.................    25,000          2.49           24.75        8/10/05    --         389,250     986,250
                                       20,000                         23.00       10/13/05    --         289,200     733,200
Peter D. Staple....................    10,000          2.22           24.75        8/10/05    --         155,700     394,500
                                       30,000                         23.00       10/13/05    --         433,800   1,099,800
</TABLE>
 
- ------------------------
(1) The  amounts  represent  certain  assumed rates  of  appreciation  over  the
    exercise  price per  share (before  taxes). Actual  gains, if  any, on stock
    option exercises  are dependent  on the  future performance  of ALZA  Common
    Stock.  There can be no  assurance that any of  the values reflected in this
    table will be achieved.
 
(2) For a description of  the material terms of the  options, see footnote 4  of
    the Summary Compensation Table.
 
(3)  Options were granted at an exercise price equal to the fair market value of
    ALZA Common Stock, as determined by reference to the average of the high and
    low price reported on the New York Stock Exchange on the date of grant.
 
                                       6
<PAGE>
       1995 AGGREGATED OPTION EXERCISES AND FISCAL YEAR-END OPTION VALUES
 
    The following table sets forth with respect to the Named Executive  Officers
certain information relating to options exercised during fiscal 1995.
 
<TABLE>
<CAPTION>
                                                              NUMBER OF SECURITIES        VALUE OF UNEXERCISED
                                                             UNDERLYING UNEXERCISED     IN-THE-MONEY OPTIONS AT
                                   SHARES                  OPTIONS AT FISCAL YEAR-END     FISCAL YEAR-END (2)
                                 ACQUIRED ON     VALUE     --------------------------  --------------------------
NAME                              EXERCISE    REALIZED (1) EXERCISABLE  UNEXERCISABLE  EXERCISABLE  UNEXERCISABLE
- -------------------------------  -----------  -----------  -----------  -------------  -----------  -------------
<S>                              <C>          <C>          <C>          <C>            <C>          <C>
Dr. Ernest Mario...............      10,000    $  (1,250)     230,000        650,000   $   977,500  $   2,518,750
Dr. Alejandro Zaffaroni........      --           --           --            --            --            --
Dr. Felix Theeuwes.............      --           --           52,000        174,000       --             151,250
Dr. Samuel R. Saks.............      --           --           15,000        135,000       --             115,000
Peter D. Staple................      --           --           20,000         80,000        10,000         65,000
</TABLE>
 
- ------------------------
(1)  Market  value of  ALZA Common  Stock based  on the  closing sales  price as
    reported on  the composite  tape at  the exercise  date minus  the  exercise
    price.
 
(2)  Market value of ALZA  Common Stock at fiscal  year-end based on the closing
    sales price as reported on the composite tape on December 29, 1995 ($24 1/2)
    minus the exercise price  of "in-the-money" options. At  March 1, 1996,  the
    closing sales price of ALZA Common Stock was $33 5/8.
 
                          CERTAIN EXECUTIVE AGREEMENTS
 
    ALZA  has entered into agreements (each  an "Executive Agreement") with each
of its  eight  executive officers,  other  than  Dr. Mario  and  Dr.  Zaffaroni,
pursuant  to which certain severance payments would  be made in the event of the
executive's termination, other than for  cause, following a "change in  control"
of ALZA (as defined in the Executive Agreement).
 
    If  the executive's employment  were terminated by  ALZA during the two-year
period following a change in control (the "Severance Period") without "cause" or
by the executive for "good reason" (as defined in the Executive Agreement),  the
executive  would be entitled to receive a  lump sum cash severance payment equal
to two times the sum of  his salary and bonus paid  or accrued in the 12  months
immediately  preceding  his termination.  (Such amount  would  be reduced,  on a
monthly basis, if the termination occurred  more than one year after the  change
in  control.)  In addition  to the  severance payments,  the executive  would be
entitled to a pro  rata portion of  all bonuses and  awards relating to  periods
that  have not  been completed as  of the termination  date and a  lump sum cash
amount equal to the  difference, if any,  between the value  of the benefits  he
would  have  received  under  the  Company's  retirement,  pension  or  deferred
compensation arrangements had he been fully vested under such arrangements,  and
the  benefits he is otherwise entitled to receive under such arrangements at the
time of  termination.  The  executive  would also  receive  medical  and  dental
benefits  for  up  to two  years.  All  outstanding options  would  become fully
exercisable (to the extent they have not previously become exercisable), and the
executive would be entitled to a cash-out of all options.
 
      COMPENSATION AND BENEFITS COMMITTEE REPORT ON EXECUTIVE COMPENSATION
 
    The Compensation and Benefits  Committee (the "Committee")  of the Board  of
Directors  is generally responsible for decisions concerning the compensation to
be paid  to ALZA's  executive officers.  The Committee  consists of  Dr.  Glaser
(Chairman) and Messrs. Morton and Stein, each of whom is a non-employee director
of  ALZA.  In determining  compensation policies,  the  Committee has  access to
compensation surveys for regional high technology companies (which compete  with
ALZA  in  the  recruitment  of  senior  personnel)  and  national pharmaceutical
industry compensation  information.  The  Committee also  consults  with  ALZA's
Senior  Director of Compensation and Benefits. Set  forth below is the report of
the Committee with respect to ALZA's  compensation policies during 1995 as  they
affected the company's Chief Executive Officer and the company's other executive
officers.
 
                                       7
<PAGE>
COMPENSATION POLICIES AFFECTING EXECUTIVE OFFICERS
 
    ALZA's  compensation policies affecting its  executive officers are designed
to provide targeted total compensation levels that are competitive with those of
regional high  technology companies  and national  pharmaceutical companies,  in
order  to assist the  company in attracting  and retaining qualified executives.
The Committee believes that ALZA's compensation structure has historically  been
at  the low  end of  pharmaceutical companies with  respect to  salary and bonus
payable to its executive officers generally, and to its Chief Executive  Officer
in  particular. The S&P Drugs Index,  the industry group included for comparison
in  "Performance  Graphs"  below,  consists  of  large  national  pharmaceutical
companies,  which have been  used as a  reference in setting  salaries of ALZA's
executives.
 
    ALZA's compensation policies  take into account  ALZA's overall  performance
during  the prior  year, as  well as the  achievements and  contributions to the
company during the year by each individual executive officer and the operational
areas  of  the  company  for  which  he  is  responsible.  In  addition,  ALZA's
compensation  policies recognize the importance of stock ownership by, and stock
option programs  for,  executives in  order  to promote  identity  of  long-term
interests between the executives and the stockholders of ALZA.
 
    In determining the compensation to be paid to ALZA's executive officers, the
Committee  employs  compensation policies  designed  to align  compensation with
ALZA's overall  business  strategy,  values and  management  initiatives.  These
policies   are  intended  to  (i)  reward  executives  for  long-term  strategic
management  and  the   enhancement  of   stockholder  value;   (ii)  support   a
performance-oriented  environment that  rewards achievement  of internal company
objectives; (iii) recognize company  performance compared to performance  levels
of  comparable companies; and (iv) attract and retain executives whose abilities
are critical to the long-term success and competitiveness of ALZA. As a  result,
compensation consists of salary and bonus, which provide current incentives, and
stock options, which provide longer term incentives.
 
    The key components of executive officer compensation at ALZA are (i) salary,
which   is  based  on  factors  such   as  the  individual  officer's  level  of
responsibility for meeting the company's financial and strategic objectives  and
comparison  to similar positions  in the company  and comparable companies; (ii)
cash bonus awards,  which are  based on the  performance of  the executive,  the
performance  of  his or  her operational  groups, and  the performance  of ALZA,
measured in terms of  attainment of ALZA's  financial and strategic  objectives;
and  (iii)  stock  option grants,  which  are  intended to  align  the executive
officers' interests in the company's long-term success with the interests of the
company's stockholders, as measured by changes over time in the company's  stock
trading price.
 
    Stock options are an integral part of each executive officer's compensation.
The  Committee  believes that  the opportunity  for stock  appreciation, through
exercise of stock options that vest  over time, closely aligns the interests  of
the  executive officers with ALZA's stockholders.  The size of individual awards
take into  account  the  executive  officer's salary,  the  number  and  vesting
schedule  of outstanding options  held by the officer  and past contributions to
ALZA. No one  factor is given  special weight, but  all are part  of an  overall
assessment.
 
    The  compensation to be paid to any  particular executive has not been based
on  any  particular   mathematical  formula.  Rather,   the  Committee   reviews
objectives,  accomplishments,  performance  (including  that  indicated  in  the
company's peer  evaluation  process)  and  compensation  as  a  whole  for  each
executive (and all executives) and makes appropriate compensation determinations
in the exercise of its business judgment.
 
                                       8
<PAGE>
RELATIONSHIP OF CORPORATE PERFORMANCE TO COMPENSATION PLANS
 
    The  executive officers'  compensation during  1995 comprised  the following
elements: (i) base salary; (ii) cash  bonuses based on a combination of  overall
company  and individual  performance during the  year; and (iii)  grant of stock
options. Both  base compensation  and  cash bonus  take into  consideration  the
achievement  by ALZA of  the financial and  strategic objectives described below
established by the Board of  Directors for the company  at the beginning of  the
year,  and  the individual's  (and his  or  her operating  groups') contribution
toward achieving  those objectives.  The  option grant  takes into  account  the
executive's  respective  number  and vesting  schedule  of  outstanding options,
salary and contributions to the company.
 
    ALZA's corporate  performance  measurements  focus  on  both  financial  and
strategic objectives. During 1995, ALZA achieved the strategic objectives set by
its Board of Directors, which related to the following general areas:
 
    - extending ALZA's technological leadership position in drug delivery;
 
    - sustaining  1994 levels of ALZA's  product development business with other
      pharmaceutical companies;
 
    - increasing ALZA's direct commercialization activities;
 
    - obtaining increased royalties and fees as compared with 1994;
 
    - accelerating  development   of   products   with   Therapeutic   Discovery
      Corporation; and
 
    - increasing earnings per share significantly over 1994.
 
OTHER COMPENSATION PLANS
 
    ALZA  has adopted  certain broad-based employee  benefit plans  in which the
executive officers may participate on the same basis as other employees who meet
eligibility criteria, subject to legal limitations  on the benefits that may  be
made  available to  an individual  executive officer.  During 1995,  these plans
included an Employee  Stock Purchase  Plan qualified  under Section  423 of  the
Internal  Revenue Code, under which an individual  could elect to purchase up to
$25,000 of ALZA's Common Stock at a price equal to 85 percent of its fair market
value, and the contribution by ALZA for the benefit of each employee  (including
executive officers) to the ALZA Retirement Plan (a defined contribution plan) of
an amount based on the employee's base salary and age.
 
CHIEF EXECUTIVE OFFICER'S COMPENSATION
 
    Dr. Ernest Mario, ALZA's Chief Executive Officer, received an increase of 5%
in  salary for 1995 over his 1994 salary, for a total annual salary of $570,840.
He also was granted an option to purchase 75,000 shares of Common Stock, vesting
after three years  and expiring in  2005. The  exercise price of  the option  is
$24.75,  the fair market  value of the Common  Stock on the  date the option was
granted. The Committee believes  that Dr. Mario's  salary is on  the low end  of
salaries  for chief  executive officers  of other  technology-based companies of
similar size and in  the same geographic  region as ALZA, as  well as for  chief
executives of pharmaceutical companies on a nationwide basis. In 1995, Dr. Mario
provided  strong leadership to  the company in its  achievement of its strategic
and financial objectives for the year  and in progressing toward meeting  ALZA's
long-term objectives, and accordingly was awarded a bonus of $100,000.
 
                                       9
<PAGE>
POLICY ON DEDUCTIBILITY OF EXECUTIVE OFFICER COMPENSATION
 
    Section  162(m) of the  Internal Revenue Code generally  places a $1 million
per person  limit on  the deduction  a publicly  held corporation  may take  for
compensation paid to its chief executive officer and its four other highest paid
executive   officers  unless,  in   general,  the  compensation   is  exempt  as
"performance based." For stock compensation  to be "performance based,"  Section
162(m)  requires a limit to be set on  the number of options that may be granted
to employees subject to the deduction cap. The Board of Directors has approved a
limit of 200,000  as the maximum  number of shares  as to which  options may  be
granted  to any employee, consultant or  director under the Amended and Restated
Stock Plan in any one-year period, and a limit of 750,000 as the maximum  number
of  shares as  to which options  may be granted  in connection with  an offer of
employment. These limitations allow gains  realized upon exercise of options  to
qualify  as "performance based" and, therefore, to be excluded from compensation
subject to the  $1 million deductibility  limit. ALZA believes  that all of  its
compensation  paid to date meets the requirements for deductibility. In general,
the Committee  will  consider the  deductibility  limits of  Section  162(m)  in
determining executive compensation.
 
                      COMPENSATION AND BENEFITS COMMITTEE
 
                         Dr. Robert J. Glaser, Chairman
                                 Dean O. Morton
                                  Isaac Stein
 
                                       10
<PAGE>
                               PERFORMANCE GRAPHS
 
FIVE-YEAR TOTAL RETURN
 
    The  rules  of  the Securities  and  Exchange Commission  require  that ALZA
include in this Proxy Statement  a line-graph presentation comparing  cumulative
stockholder  returns on  an indexed basis  with the  S&P 500 Index  and either a
nationally recognized  industry standard  index or  an index  of peer  companies
selected  by ALZA for the five years  ending December 31, 1995. ALZA has elected
to use the  S&P Drugs  Index for purposes  of the  performance comparison  which
appears  below. The past performance of ALZA's  Common Stock is no indication of
future performance.
 
    The graph  has been  prepared to  give effect  to the  distribution to  ALZA
stockholders  on June 11, 1993  of units (the "Units"),  each Unit consisting of
one share of Class A Common  Stock of Therapeutic Discovery Corporation  ("TDC")
and  one warrant to purchase  one-eighth of one share of  ALZA Common Stock at a
price of $65 per  share, exercisable at  any time commencing  on the earlier  of
June 11, 1996 or the date ALZA exercises its purchase option with respect to all
outstanding  Class A Common Stock of TDC and expiring on December 31, 1999. Each
holder of Common Stock of ALZA received one Unit for every ten shares of  Common
Stock  held on  May 28, 1993,  the record  date for the  distribution. The graph
below assumes that the one-tenth of one Unit received in respect of one share of
ALZA Common Stock  was sold  on the  distribution date  (June 11,  1993) at  the
closing  sale price  of the  Units on such  date ($6.25  per full  Unit) and the
proceeds thereof immediately  applied toward  the purchase of  0.0239 shares  of
ALZA's  Common Stock at a  price based on the closing  sales price of the Common
Stock on such date ($26.125).
 
                COMPARISON OF FIVE-YEAR CUMULATIVE TOTAL RETURN
                AMONG ALZA, THE S&P 500 AND THE S&P DRUGS INDEX
 
EDGAR REPRESENTATION OF DATA POINTS USED IN PRINTED GRAPHIC
 
<TABLE>
<CAPTION>
             ALZA      S&P DRUGS    S&P 500
<S>        <C>        <C>          <C>
1990         $100.00      $100.00    $100.00
1991          193.12       164.78     130.47
1992          184.77       132.09     140.41
1993          113.71       120.88     154.57
1994           72.45       140.73     156.61
1995           98.62       241.32     215.46
</TABLE>
 
The S&P Drugs Index includes  the following: Eli Lilly, Schering-Plough,  Merck,
Syntex  (through  6/6/94),  Pfizer,  Upjohn (through  11/2/95)  and  Pharmacia &
Upjohn, Inc. (effective 11/3/95).
 
                                       11
<PAGE>
TEN-YEAR TOTAL RETURN
 
    The  following graph compares  the cumulative stockholder  returns on ALZA's
Common Stock with the cumulative total return  of the S&P 500 Index and the  S&P
Drugs  Index for  the ten  years ending  December 31,  1995. ALZA  has presented
ten-year data to provide a longer term perspective which is consistent with  the
timeframe  for ALZA's business of  developing, manufacturing and commercializing
pharmaceutical products. The graph  below has been  prepared in accordance  with
the  same  assumptions used  for  the five-year  graph  above. In  addition, the
ten-year graph  below  has  been  prepared to  give  effect  to  a  subscription
offering,  completed in  1988, to  ALZA stockholders.  Each ALZA  stockholder of
record on November 18,  1988 received one  right for each  share of ALZA  Common
Stock  held. The graph below assumes that one subscription right was sold on the
first day of such  offering (November 22,  1988) at the price  of the rights  on
such  date  ($0.50), and  the proceeds  thereof  immediately applied  toward the
purchase of 0.0423 shares of ALZA's Common Stock at a price based on the closing
sales price of ALZA's Common Stock  on such date ($11.81). The past  performance
of ALZA's Common Stock is no indication of future performance.
 
                 COMPARISON OF TEN-YEAR CUMULATIVE TOTAL RETURN
                AMONG ALZA, THE S&P 500 AND THE S&P DRUGS INDEX
 
EDGAR REPRESENTATION OF DATA POINTS USED IN PRINTED GRAPHIC
 
<TABLE>
<CAPTION>
             ALZA      S&P DRUGS    S&P 500
<S>        <C>        <C>          <C>
1985         $100.00      $100.00    $100.00
1986          121.14       138.27     118.56
1987          174.80       153.12     124.81
1988          151.69       178.23     145.30
1989          297.44       266.90     191.35
1990          344.90       305.07     185.40
1991          666.07       502.69     241.89
1992          637.26       402.96     260.32
1993          391.83       368.76     286.56
1994          249.66       429.32     290.35
1995          339.81       736.20     399.46
</TABLE>
 
The  S&P Drugs Index includes the  following: Eli Lilly, Schering-Plough, Merck,
Syntex (through  6/6/94),  Pfizer,  Upjohn (through  11/2/95)  and  Pharmacia  &
Upjohn, Inc. (effective 11/3/95).
 
                                       12
<PAGE>
                           BENEFICIAL STOCK OWNERSHIP
 
    The  following table sets forth beneficial  ownership of ALZA's Common Stock
as of March 1, 1996  (except as otherwise noted) (i)  by each person, entity  or
"group"  of persons or  entities known by  ALZA to be  beneficial owners of more
than 5% of ALZA's Common Stock,  (ii) by each director, including nominees,  and
each  of the Named Executive  Officers, and (iii) by  all executive officers and
directors as a group. Except as described below, each person has sole voting and
dispositive power with respect to the Common Stock described in the table.
 
<TABLE>
<CAPTION>
                                                                     AMOUNT AND NATURE OF
                                                                          BENEFICIAL           PERCENT OF
NAME                                                                   OWNERSHIP (1)(2)         CLASS (3)
- -----------------------------------------------------------------  -------------------------  -------------
<S>                                                                <C>                        <C>
J.P. Morgan & Co. Incorporated ..................................            6,365,020                7.6%
 and its subsidiaries
 60 Wall Street
 New York, NY (4)
Brinson Partners, Inc. ..........................................            4,655,250                5.5
 and affiliated entities
 209 South LaSalle
 Chicago, IL (5)
William G. Davis.................................................               42,000             --
Martin S. Gerstel................................................              298,700             --
Dr. Robert J. Glaser.............................................               18,884             --
Dr. Ernest Mario.................................................              260,000             --
Dean O. Morton...................................................               18,000             --
Rudolph A. Peterson..............................................               47,163             --
Dr. Samuel R. Saks...............................................               15,000             --
Peter D. Staple..................................................               40,377             --
Isaac Stein......................................................               23,608             --
Julian N. Stern..................................................              131,679             --
Dr. Felix Theeuwes...............................................              236,773             --
Dr. Alejandro Zaffaroni..........................................              954,600                1.1
All Executive Officers and Directors as a group (17 persons).....            2,323,726                2.7
</TABLE>
 
- ------------------------
(1) Includes outstanding stock options, exercisable on or before April 30, 1996,
    to purchase the number of shares of ALZA Common Stock as follows: 40,000 for
    Mr. Davis; 115,000 for  Mr. Gerstel; 8,000 for  Dr. Glaser; 230,000 for  Dr.
    Mario;  8,000 for Mr. Morton; 17,000 for  Mr. Peterson; 15,000 for Dr. Saks;
    40,000 for Mr. Staple;  12,000 for Mr. Stein;  24,000 for Mr. Stern;  56,000
    for  Dr. Theeuwes; and 676,100 for all executive officers and directors as a
    group.
 
(2) Excludes shares covered by outstanding warrants, each to purchase one-eighth
    of one share of ALZA Common Stock  at a price of $65 per share,  exercisable
    at  any time  commencing on the  earlier of June  11, 1996 or  the date ALZA
    exercises its purchase option with respect to all outstanding Class A Common
    Stock of TDC and expiring on December 31, 1999.
 
(3) Percentages  are  not  shown  if  holdings  total  less  than  1%  of  total
    outstanding shares.
 
(4)  Information  is  as of  December  29, 1995  as  provided by  the  holder in
    Amendment No. 13 to its Schedule 13G dated December 29, 1995 and filed  with
    the  Securities and Exchange  Commission. As to such  shares, the holder has
    provided the following information: sole  voting power -- 3,266,896  shares;
    shared  voting power --  81,397 shares; sole  dispositive power -- 6,174,922
    shares; and shared dispositive power -- 108,497 shares.
 
(5) Information is  as of  February 9,  1996 as provided  by the  holder in  its
    Schedule  13G  dated February  9,  1996 and  filed  with the  Securities and
    Exchange Commission. The holder has shared voting and dispositive power with
    respect to all shares.
 
                                       13
<PAGE>
                              CERTAIN TRANSACTIONS
 
    In October  1995,  Mr.  Adrian  Gerber,  ALZA's  Executive  Vice  President,
Commercial  Development, retired from  employment with ALZA.  In connection with
his retirement, ALZA  made a lump  sum payment of  approximately $48,000 to  Mr.
Gerber.  ALZA paid medical and dental  insurance premiums for Mr. Gerber through
March 1996. Mr. Gerber  is providing consulting services  to ALZA, for which  he
was  paid $64,500 for 1995. Upon completion  of six months of such services, and
achievement of specified goals in  connection therewith, Mr. Gerber's  principal
and  accrued interest on  his loan from  the Company ($113,892  of principal and
accrued interest as of December 31, 1995) will be forgiven. The loan was made in
connection  with  Mr.  Gerber's  relocation  to  California  when  he   accepted
employment  with ALZA  in 1990.  During 1995,  ALZA paid  Mr. Gerber  a mortgage
differential of $7,088 as provided for in his employment arrangement with  ALZA.
In  connection with Mr. Gerber's retirement, the vesting date of his outstanding
stock options was accelerated.
 
    In September 1995, ALZA made a loan  to Bruce C. Cozadd, its Vice  President
and  Chief Financial Officer, in the  principal amount of $86,000, in connection
with the purchase of his principal residence. The loan bears interest at a  rate
of  6.04% per annum  and is payable in  full in September  2000. On December 31,
1995, the  outstanding  principal  and  accrued interest  on  the  loan  totaled
$87,537.  Repayment of  the loan  is secured by  a second  deed of  trust on Mr.
Cozadd's residence.
 
    In July 1995, ALZA made  a loan to Peter D.  Staple, its Vice President  and
General  Counsel, in  the principal  amount of  $88,000, in  connection with the
purchase of his principal residence. The loan bears interest at a rate of  6.28%
and  is payable  in full  in July  2000. On  December 31,  1995, the outstanding
principal on the loan  totaled $88,000 and all  accrued interest had been  paid.
Repayment  of the  loan is  secured by a  second deed  of trust  on Mr. Staple's
residence.
 
                              STOCKHOLDER PROPOSAL
 
    Mr. William Steiner, 4  Radcliff Drive, Great Neck,  NY 11024, owner of  350
shares  of Common Stock, has  given notice that he,  or his representative, will
present the resolution set  forth below at the  Annual Meeting. For the  reasons
set  forth below,  ALZA's Board  of Directors  recommends a  vote "AGAINST" this
proposal. The text of Mr. Steiner's proposal is as follows:
 
    "RESOLVED, that the stockholders  of the Company request  that the Board  of
Directors  take the necessary steps, in accordance with state law, to declassify
the Board  of  Directors  so  that all  directors  are  elected  annually,  such
declassification  to be effected in a manner  that does not affect the unexpired
terms of directors previously elected.
 
    "SUPPORTING STATEMENT: The election of  directors is the primary avenue  for
stockholders  to influence corporate governance  policies and to hold management
accountable for  its  implementation  of  those policies.  I  believe  that  the
classification of the Board of Directors, which results in only a portion of the
Board  being elected annually, is  not in the best  interests of the Company and
its stockholders.
 
    "The Board of Directors of the Company is divided into three classes serving
staggered three-year terms.  I believe  that the Company's  classified Board  of
Directors maintains the incumbency of the current Board and therefore of current
management, which in turn limits management's accountability to stockholders.
 
    "The  elimination of the  Company's classified Board  would require each new
director to stand for election annually and allow stockholders an opportunity to
register their  views on  the performance  of the  Board collectively  and  each
director  individually. I believe this  is one of the  best methods available to
stockholders to insure that the Company will  be managed in a manner that is  in
the best interests of the stockholders.
 
    "I am a founding member of the Investors Rights Association of America and I
believe  that concerns  expressed by companies  with classified  boards that the
annual election of all directors could
 
                                       14
<PAGE>
leave companies without experienced directors  in the event that all  incumbents
are  voted out by stockholders, are unfounded. In my view, in the unlikely event
that stockholders vote  to replace  all directors, this  decision would  express
stockholder  dissatisfaction with the  incumbent directors and  reflect the need
for change.
 
    "I urge your support, vote for this resolution."
 
COMMENT AND RECOMMENDATION BY BOARD
 
    ALZA'S BOARD  OF  DIRECTORS  OPPOSES THE  STOCKHOLDER  PROPOSAL.  The  Board
believes  that the  success of  the Company  in producing  stockholder value, as
reflected in capital appreciation, requires long-term strategic planning as well
as careful  and consistent  application  of the  Company's financial  and  other
resources.  A classified Board helps provide continuity in direction by ensuring
that a majority of the  Board at any given time  would have prior experience  as
directors of the Company. An abrupt change of control could be disruptive to the
Company   in  achieving  its   long-term  strategic  goals   and  might  deprive
stockholders of the opportunity to realize the full value of their investment.
 
    A classified Board enhances the ability  of the Company's Board to  evaluate
and  respond to takeover attempts in a manner which maximizes stockholder value.
In the  particular case  of  a research-based  company  like the  Company  where
product  development often requires many years, market price at a given time may
not be an accurate measure of  the Company's intrinsic value. Accordingly,  ALZA
could  be vulnerable to unfair and  abusive takeover tactics, and an unsolicited
proposal to acquire  or restructure the  Company that is  not negotiated with  a
classified  Board  could  result in  a  price  which is  not  indicative  of the
Company's true value.
 
    The Board  does not  believe  that a  classified board  limits  management's
accountability   and   responsiveness   to  the   Company's   stockholders.  The
stockholders retain their ability to  replace incumbent directors or to  propose
alternate  nominees  for the  class  of directors  to  be elected  at  an annual
meeting. By altering the composition of the Board, the stockholders can properly
and effectively express  their views with  respect to, and  thus influence,  the
Company's  policies. The Board believes that incumbent directors who continue in
office will be aware of and influenced by any such stockholder action.
 
    Under  the  corporation  law  of  the  state  of  Delaware,  where  ALZA  is
incorporated,  the  Company's Certificate  of Incorporation  must be  amended in
order to declassify the Board of  Directors. Such an amendment to the  Company's
Certificate  of Incorporation contemplated  by this proposal  must either (i) be
approved by 75% of the members of  the Board of Directors, or (ii) be  submitted
to  the stockholders for a vote, and approved  by the holders of at least 80% of
the outstanding shares of capital  stock of the Company  entitled to vote in  an
election  of directors. The Board of Directors  is opposed to such an amendment.
The stockholder proposal is merely a recommendation that the Board take  certain
actions,  and  not  a  proposal  to  amend  the  Certificate  of  Incorporation.
Therefore, a vote in favor of the proposal is only an advisory recommendation to
the Board to submit an amendment to  the Certificate of Incorporation to a  vote
of the stockholders.
 
BOARD RECOMMENDATION AND VOTE REQUIRED
 
    THE  BOARD OF DIRECTORS RECOMMENDS THAT  THE STOCKHOLDERS VOTE "AGAINST" THE
STOCKHOLDER PROPOSAL. The affirmative vote of a majority of the shares of Common
Stock present or represented and entitled to  a vote at the meeting is  required
to   approve  the  proposal.  Proxies  received  will  be  voted  "AGAINST"  the
stockholder proposal unless marked to the contrary.
 
                      RATIFICATION OF INDEPENDENT AUDITORS
 
    The Board recommends that the stockholders ratify the appointment of Ernst &
Young LLP as independent auditors to audit the financial statements of ALZA  for
the  year  ending December  31, 1996.  Ernst  & Young  LLP (and  its predecessor
company) has acted as ALZA's auditor since ALZA's inception. A representative of
Ernst &  Young  LLP  will  be  present at  the  Annual  Meeting,  will  have  an
opportunity  to make  a statement if  he or  she desires to  do so,  and will be
available to respond to
 
                                       15
<PAGE>
appropriate questions. A favorable  vote of a majority  of the shares of  Common
Stock  present or represented and entitled to vote at the meeting is required to
ratify the appointment of Ernst & Young LLP.
 
                         ANNUAL REPORT TO STOCKHOLDERS
 
    ALZA's Annual Report to Stockholders for  the year ended December 31,  1995,
containing  the audited consolidated balance sheets  as of December 31, 1995 and
1994 and the related consolidated statements of operations, stockholders' equity
and cash flows for  each of the  past three fiscal years,  is being mailed  with
this Proxy Statement to stockholders entitled to notice of the Annual Meeting.
 
                             STOCKHOLDER PROPOSALS
 
    ALZA  received  a stockholder  proposal for  this  Proxy Statement  from the
Carpenters Pension  Fund which  recommended  changes in  the provisions  of  the
Company's  Certificate  of  Incorporation  concerning  the  issue  of directors'
personal liability and  indemnification. After discussions  between the  Company
and  the stockholder, the stockholder has withdrawn the proposal and the Company
has agreed to study the issue further and discuss it with the stockholder in the
future.
 
    ALZA will,  in future  proxy statements  of the  Board, include  stockholder
proposals  complying with  the applicable rules  of the  Securities and Exchange
Commission and  the  procedures set  forth  in ALZA's  Bylaws.  In order  for  a
proposal  by a stockholder  to be included  in the proxy  statement of the Board
relating to the annual meeting of stockholders to be held in the spring of 1997,
that proposal must be received in writing by the Secretary of ALZA no later than
December 2, 1996.
 
                                 OTHER MATTERS
 
    The Board knows of  no other matters  that will be  presented at the  Annual
Meeting.  If, however, any  matter is properly presented  at the Annual Meeting,
the proxy solicited hereby will be voted in accordance with the judgment of  the
proxyholders.
 
                                          By Order of the Board of Directors,
                                          JULIAN N. STERN
                                          SECRETARY
Palo Alto, California
April 1, 1996
 
YOU ARE CORDIALLY INVITED TO ATTEND THE ANNUAL MEETING IN PERSON. WHETHER OR NOT
YOU  PLAN  TO ATTEND  THE  MEETING, YOU  ARE REQUESTED  TO  SIGN AND  RETURN THE
ACCOMPANYING PROXY  CARD  AS  SOON  AS POSSIBLE  IN  THE  ACCOMPANYING  POSTPAID
ENVELOPE. YOUR DOING SO MAY SAVE ALZA THE EXPENSE OF A SECOND MAILING.
 
                                       16
<PAGE>

                               DETACH HERE


                                  PROXY


                            ALZA CORPORATION

        THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned hereby appoint(s) JULIAN N. STERN, PETER D. STAPLE and 
BRUCE C. COZADD, or any of them, each with full power of substitution, the 
lawful attorneys and proxies of the undersigned to attend the Annual Meeting 
of Stockholders of ALZA CORPORATION to be held on May 23, 1996 and at any 
adjournments and postponements thereof, to vote the number of shares the 
undersigned would be entitled to vote if personally present, and to vote in 
their discretion upon any other business that may properly come before the 
meeting.

     THIS PROXY, WHEN PROPERLY EXECUTED, WILL BE VOTED IN THE MANNER DIRECTED 
BY THE UNDERSIGNED STOCKHOLDER(S). IF NO DIRECTION IS MADE, THIS PROXY WILL 
BE VOTED "FOR" PROPOSALS 1 AND 2 AND "AGAINST" PROPOSAL 3. THIS PROXY MAY BE 
REVOKED AT ANY TIME PRIOR TO THE TIME IT IS VOTED BY ANY MEANS DESCRIBED IN 
THE ACCOMPANYING PROXY STATEMENT.

                    CONTINUED AND TO BE SIGNED ON REVERSE SIDE

                                SEE REVERSE
                                    SIDE






<PAGE>

                               DETACH HERE

      Please mark
/ X / votes as in
      this example.
- -----------------------------------------------------------------------
      THE BOARD OF DIRECTORS OF ALZA CORPORATION UNANIMOUSLY RECOMMENDS
                   A VOTE "FOR" PROPOSALS 1 AND 2:
- -----------------------------------------------------------------------
1. To Elect as Class III Directors:
NOMINEES: Dr. Ernest Mario, Isaac Stein and 
          Dr. Alejandro Zaffaroni
         
          FOR     WITHHELD
          / /       / /

/ / ___________________________________
 For all nominees except as noted above

/ / MARK HERE FOR ADDRESS CHANGE AND NOTE
    BELOW

2. To ratify the appointment of Ernst & Young    FOR   AGAINST   ABSTAIN
   LLP as ALZA's independent public auditors     / /    / /        / /
   for fiscal 1996.

- ------------------------------------------------------
THE BOARD OF DIRECTORS OF ALZA CORPORATION UNANIMOUSLY
RECOMMENDS A VOTE "AGAINST" PROPOSAL 3:
- -----------------------------------------------------
3. Stockholder proposal        FOR   AGAINST   ABSTAIN
   regarding declassification  / /     / /       / /
   of board of directors.
- -------------------------------------------------------
Please date and sign exactly as name(s) appear(s) hereon.
If shares are held jointly, each holder should sign.
Please give full title and capacity in which signing if
not signing as an individual stockholder.


Signature:_______________ Date:________  Signature:_____________ Date:______

      


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