AMERICAN HOME PRODUCTS CORP
SC 13D/A, 1999-05-21
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                 SCHEDULE 13D/A

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 5)*

                               Immunex Corporation
                                (Name of Issuer)

                          Common Stock, $.01 par value
                         (Title of Class of Securities)

                                   45252810 2
                                 (CUSIP Number)

                           LOUIS L. HOYNES, JR., ESQ.
                    Senior Vice President and General Counsel
                       American Home Products Corporation
                      5 Giralda Farms, Madison, N.J. 07940
                                 (973) 660-5000
            (Name, Address and Telephone Number of Person Authorized
                     to Receive Notices and Communications)

                                  May 20, 1999
             (Date of Event which Requires Filing of this Statement)

     If the filing person has previously filed a statement on Schedule 13G to
report the acquisition which is the subject of this Schedule 13D, and is filing
this schedule because of Sections 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g),
check the following box [ ].

     Note:  Schedules  filed in paper format shall include a signed original and
five copies of the schedule,  including all exhibits.  See Section  240.13d-7(b)
for other parties to whom copies are to be sent.

     *The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page.

     The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).

<PAGE>
CUSIP No. 45252810 2

1.       NAME OF REPORTING PERSON
         S.S. or I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

         American Home Products Corporation ("Parent")
         Tax I.D. 13-2526821

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
         (a)  N/A
         (b)

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*

         WC

5.       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
         PURSUANT TO ITEMS 2(d) or 2(e)

         [ ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH

7.       SOLE VOTING POWER

         46,380,609, (includes 36,585,461 shares held by American Cyanamid
         Company ("ACY"), a wholly-owned subsidiary of Parent and also includes
         7,204,176 shares of Immunex Common Stock held by Lederle Parenterals,
         Inc., a wholly-owned subsidiary of ACY)

8.       SHARED VOTING POWER

         -0-

9.       SOLE DISPOSITIVE POWER

         46,380,609, (includes 36,585,461 shares held by American Cyanamid
         Company ("ACY"), a wholly-owned subsidiary of Parent and also includes
         7,204,176 shares of Immunex Common Stock held by Lederle Parenterals,
         Inc., a wholly-owned subsidiary of ACY)


10.      SHARED DISPOSITIVE POWER

         -0-

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         46,380,609

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

         [  ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         55.2%

14.      TYPE OF REPORTING PERSON*

         CO
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

<PAGE>
     The Statement on Schedule 13D, dated December 1, 1994 (the "Original
Statement"), filed by American Home Products Corporation, a Delaware corporation
("Parent" or "Reporting Person"), and on behalf of AC Acquisition Corp., a
Delaware corporation, as amended by Amendment No. 1, dated November 2, 1995
("Amendment No. 1"), Amendment No. 2, dated November 3, 1995 ("Amendment No.
2"), Amendment No. 3, dated November 15, 1995 ("Amendment No. 3") and Amendment
No. 4, dated April 23, 1999 ("Amendment No. 4") is hereby further amended by
this Amendment No. 5, dated May 20, 1999 ("Amendment No. 5"), to reflect certain
changes in the information previously filed relating to the outstanding Common
Stock, $.01 par value (the "Common Stock"), of Immunex Corporation, a Washington
corporation ("Immunex" or "Issuer"), which has its principal executive offices
at 51 University Street, Seattle, WA 98101. All defined terms as used in this
Amendment No. 5 shall have the meanings assigned to such terms in the Note
Agreement (as hereinafter defined) unless otherwise indicated herein.

     Item 2 of the Original Statement is hereby amended by deleting it in its
entirety and substituting the following language:

     This statement is being filed by American Home Products Corporation, a
Delaware corporation ("Parent") which has its executive offices at Five Giralda
Farms, Madison, New Jersey 07940.

     Parent is one of the world's largest research-based pharmaceutical and
health care products companies. It is a leader in the discovery, development,
manufacturing and marketing of prescription drugs and over-the-counter
medications. It is also a leader in vaccines, biotechnology, agricultural
products and animal health care.

     For information required by this Item 2 of Schedule 13D with respect to the
executive officers and directors of Parent, reference is made to Attachment A to
this Schedule 13D, which is incorporated herein by reference.

     None of Parent or, to its best knowledge, any of the persons named on
Attachment A attached hereto, has during the last five years: (i) been convicted
in a criminal proceeding (excluding traffic violations or similar misdemeanors);
or (ii) been a party to a civil proceeding of a judicial or administrative body
of competent jurisdiction and as a result of such proceeding was or is subject
to a judgment, decree or final order enjoining future violations of, or
prohibiting or mandating activities subject to, federal or state securities laws
or finding any violation with respect to such laws.

     Item 3 of the Original Statement is hereby amended to add the following
paragraph:

     The funds used by Parent to purchase the Note (as hereinafter defined) were
entirely from the Working Capital of Parent, which may include funds sourced
from commercial paper issued by Parent from time to time (including immediately
preceding the purchase of the Note) under its cash management program.

     Item 4 is hereby amended by adding the following language:

(a)  On May 20, 1999, Immunex and Parent entered into a Note Purchase Agreement
     (the "Note Agreement"), which is attached hereto as Exhibit VI and is
     hereby incorporated by reference herein, pursuant to which Immunex issued
     and sold to Parent a $450 million 3% Convertible Subordinated Note due 2006
     (the "Note") which is attached hereto as Exhibit VII and is incorporated by
     reference herein. Parent acquired the Note for investment purposes. The
     Note was purchased by Parent for $450 million in cash and is convertible,
     at the option of the holder, into Immunex Common Stock, in whole or in part
     in an amount of at least $50 million and in increments of $1 million in
     excess thereof, at any time until maturity on May 20, 2006, unless
     previously redeemed or repaid, at a conversion price of $173.68 per share,
     subject to adjustment in certain circumstances described in the Note
     Agreement ("Conversion Price"). Upon conversion, Immunex shall pay the
     holder any accrued and unpaid interest up to the date of conversion.

          The Note is not redeemable by Immunex prior to May 20, 2002.
     Commencing May 21, 2002, and until May 20, 2003, Immunex may redeem the
     Note for cash, in whole or in part in an amount of at least $50 million and
     in increments of $1 million in excess thereof, upon not less than 45 nor
     more than 60 days prior written notice, at a redemption price equal to the
     face value of the Note plus any accrued and unpaid interest up to the date
     of redemption, if the Nasdaq closing price of Immunex Common Stock for 20
     consecutive trading days up to and including the notice date equals or
     exceeds 120% of the Conversion Price. On and after May 21, 2003, and
     continuing thereafter until maturity, Immunex may redeem the Note for cash,
     in whole or in part in an amount of at least $50 million and in increments
     of $1 million in excess thereof, upon not less than 45 nor more than 60
     days prior written notice, at a redemption price equal to the face amount
     of the Note plus any accrued and unpaid interest up to the date of
     redemption, if the Nasdaq closing price of Immunex Common Stock for 20
     consecutive trading days up to and including the notice date equals or
     exceeds the Conversion Price. The Note shall remain convertible until
     redeemed or repaid.

     Item 5 is hereby amended by adding the following language:

          As of May 20, 1999, Parent, together with its wholly-owned
     subsidiaries, holds 43,789,637 shares of Immunex Common Stock. As a result
     of purchasing the Note on May 20, 1999 which is immediately convertible by
     Parent into Immunex Common Stock, Parent became the beneficial owner (as
     defined in Rule 13d-3 under the Securities Exchange Act of 1934, as
     amended) of 2,590,972 additional shares of Immunex Common Stock underlying
     the Note which, combined with the shares previously owned by Parent, equals
     46,380,609 shares of Common Stock. Parent's percentage beneficial ownership
     of Immunex Common Stock, excluding the Common Stock underlying the Note,
     equals 53.8% and, including the Common Stock issuable upon conversion of
     the Note, equals 55.2%, using 81,449,432 as the number of shares of Common
     Stock outstanding as of May 7, 1999 as set forth in the most recent
     Quarterly Report on Form 10-Q for the quarter ended March 31, 1999 filed by
     Immunex.

     Item 6 is hereby amended by adding the following language after the second
paragraph:

          On May 20, 1999, Immunex and Parent entered into the Note Agreement
     (which is incorporated herein by reference to Exhibit VI to this Statement
     on Schedule 13D), pursuant to which Immunex issued and sold to Parent the
     Note (which is incorporated herein by reference to Exhibit VII to this
     Statement on Schedule 13D) and Immunex, Parent and ACY entered into an
     Amendment (the "Amendment") to the Governance Agreement, dated December 15,
     1992, between Immunex and ACY (the "Governance Agreement") (which Amendment
     is incorporated herein by reference to Exhibit VIII to this Statement on
     Schedule 13D). The following descriptions of the Note Agreement, the Note
     and the Amendment and those contained in other items to this statement on
     Schedule 13D are qualified in their entirety by reference to the exhibits
     attached hereto which are incorporated by reference herein.

          The Note, which was purchased on May 20, 1999 by Parent for $450
     million, bears interest at 3% per annum, payable semi-annually in arrears
     in cash on April 30 and October 30 of each year, commencing on October 30,
     1999. The Note matures on May 20, 2006. The Note is convertible, at the
     option of the holder, into Immunex Common Stock, in whole or in part in an
     amount of at least $50 million and in increments of $1 million in excess
     thereof, at any time until maturity, unless previously redeemed or repaid,
     at the Conversion Price of $173.68 per share, subject to adjustment in
     certain circumstances described in the Note Agreement. Upon conversion,
     Immunex shall pay the holder any accrued and unpaid interest up to the date
     of conversion.

          The Note is not redeemable by Immunex prior to May 20, 2002.
     Commencing May 21, 2002, and until May 20, 2003, Immunex may redeem the
     Note for cash, in whole or in part in an amount of at least $50 million and
     in increments of $1 million in excess thereof, upon not less than 45 nor
     more than 60 days prior written notice, at a redemption price equal to the
     face value of the Note plus any accrued and unpaid interest up to the date
     of redemption, if the Nasdaq closing price of Immunex Common Stock for 20
     consecutive trading days up to and including the notice date equals or
     exceeds 120% of the Conversion Price. On and after May 21, 2003, and
     continuing thereafter until maturity, Immunex may redeem the Note for cash,
     in whole or in part in an amount of at least $50 million and in increments
     of $1 million in excess thereof, upon not less than 45 nor more than 60
     days prior written notice, at a redemption price equal to the face amount
     of the Note plus any accrued and unpaid interest up to the date of
     redemption, if the Nasdaq closing price of Immunex Common Stock for 20
     consecutive trading days up to and including the notice date equals or
     exceeds the Conversion Price. The Note shall remain convertible until
     redeemed or repaid.

          The Note is subordinated to all existing and future indebtedness of
     Immunex related to borrowed money or like obligations that is not by its
     terms subordinated to other indebtedness of Immunex.

          Under the Note Agreement, Events of Default include (a) a default by
     Immunex in payment of the principal of or premium, if any, on the Note when
     due (including upon redemption); (b) default by Immunex for 30 days in
     payment of an installment of interest on the Note when due; (c) default by
     Immunex for 60 days after notice in the observance or performance of any
     other covenant in the Note transaction documents; (d) failure to perform
     any conversion and the continuation of such failure for at least 15 days;
     (e) certain events of insolvency, bankruptcy or reorganization; (f) default
     in respect of other indebtedness of Immunex or its subsidiaries exceeding
     $5 million; (g) the existence of a certain type of unsatisfied judgment
     against Immunex; or (h) other events of default specified in the Note
     Agreement.

          The Note Agreement includes representations and warranties with
     respect to the due organization of Immunex, the authorization for Immunex
     to enter into the Note Agreement and issue the Note, and certain other
     representations and warranties. In addition, the Note Agreement provides
     that Immunex will use the proceeds from issuance of the Note to fund the
     acquisition of additional assets as may be approved by the Immunex Board of
     Directors pursuant to the terms of the Governance Agreement and certain
     other covenants. In addition, the Note Agreement provides that Parent may
     transfer the Note, provided that Immunex shall have a six business day
     right to redeem the Note prior to such a transfer to an unaffiliated
     purchaser at a redemption price equal to the price proposed to be paid by
     such purchaser.

          In connection with the execution and delivery of the Note Agreement
     and the purchase and delivery of the Note, Immunex, Parent and ACY have
     entered into the Amendment pursuant to which the Governance Agreement has
     been amended to: (a) specify that the shares issuable upon conversion of
     the Note shall be deemed to be outstanding for certain purposes under the
     Governance Agreement and, accordingly, shall be included in (i) "Cyanamid's
     Interest" for purposes of Article IV; (ii) Cyanamid's "Pro Rata Share" for
     purposes of Section 2.01; (iii) Cyanamid's "Owned Shares" for purposes of
     Section 2.02 (and shall be deemed to be issued and outstanding as of the
     Quarterly Date immediately preceding the effective date of the Note); and
     (iv) "Registrable Securities" for purposes of Article VI; (b) specify that
     the Note shall not be deemed to be an interest in New Shares for purposes
     of Section 5.01(c) thereof, and that Parent shall have the right to
     transfer such Note in accordance with the terms of the Note Agreement, but
     that the Common Stock issuable upon conversion of such Note shall, when and
     if issued, be deemed to be New Shares for purposes of Article V; and (c)
     amend Section 6.03(d) of the Governance Agreement to increase the number of
     obligatory registrations from two to three.

     Item 7 is amended to add the following language at the end of item 7:

          Exhibit VI - Note Purchase Agreement ($450 million, 3% Convertible
     Subordinated Note due 2006), dated May 20, 1999, by and between Immunex and
     Parent.

          Exhibit VII - Note ($450 million, 3% Convertible Subordinated Note due
     2006), dated May 20, 1999, issued by Immunex to Parent.

          Exhibit VIII - Amendment, dated May 20, 1999, by and among Parent, ACY
     and Immunex, to the Governance Agreement.

     After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

Dated:  May 20, 1999

                                            AMERICAN HOME PRODUCTS CORPORATION


                                            By:  /s/ Robert G. Blount
                                                 Robert G. Blount
                                                 Senior Executive Vice President

<PAGE>
                                                                      Schedule A


                       Executive Officers and Directors of
                       American Home Products Corporation

     The names and titles of the executive officers and the names of the
directors of American Home Products Corporation ("AHP") and their business
addresses and principal occupations are set forth below. If no address is given,
the director's or executive officer's business address is that of AHP. Unless
otherwise indicated, each occupation set forth opposite an individuals name
refers to AHP and each individual is a United States citizen.


EXECUTIVE OFFICERS                  Position; Present Principal Occupation
- ------------------                  --------------------------------------

John R. Stafford                    Chairman, President and Chief
                                    Executive Officer

Robert G. Blount                    Senior Executive Vice President

Robert Essner                       Executive Vice President

Joseph J. Carr                      Senior Vice President

Louis L. Hoynes, Jr.                Senior Vice President and
                                    General Counsel

Robert I. Levy                      Senior Vice President-Science and
                                    Technology

William J. Murray                   Senior Vice President

David M. Olivier                    Senior Vice President

John R. Considine                   Vice President-Finance

Paul R. Jones                       Vice President and Comptroller

Rene R. Lewin                       Vice President-Human Resources

Thomas M. Nee                       Vice President-Taxes

DIRECTORS                           Position; Present Principal Occupation
- -----------                         --------------------------------------

Clifford L. Alexander, Jr.          President of Alexander & Associates,
400 C Street, NE                    Inc.(consulting firm specializing in
Washington, D.C. 20002              Workforce Inclusiveness)

Frank A. Bennack, Jr.               President and Chief Executive Officer
The Hearst Corporation              of The Hearst Corporation
959 Eighth Avenue                   (owns and operates communications
New York, New York 10019            media)

Robert G. Blount                    Listed above

Robert Essner                       Listed above

John D. Feerick                     Dean, Fordham University
Fordham University                  School of Law since 1982
School of Law
140 West 62nd Street
New York, New York 10023

John P. Mascotte                    President and Chief Executive
2301 Main Street                    Officer, Blue Cross Blue Shield
Eighth Floor                        of Kansas City, Inc.
Kansas City
Missouri 64108

Mary Lake Polan,                    Department Chair and Professor,
M.D., Ph.D                          Stanford University School of
Stanford University                 Medicine
School of Medicine
100 Pasteur Drive
Stanford, CA 94305

Ivan G. Seidenberg                  Chairman, and
Bell Atlantic                       Chief Executive Officer,
Corporation                         Bell Atlantic Corporation
1095 Avenue of the                  (telecommunications company)
Americas
New York, New York 10036

John R. Stafford                    Listed above

John R. Torell III                  Chairman, Torell Management Inc.
Torell Management Inc.              (financial advisory company)
767 Fifth Avenue
46th Floor
New York, New York 10153


<PAGE>



                                  Exhibit Index


          Exhibit VI - Note Purchase Agreement ($450 million, 3% Convertible
     Subordinated Note due 2006), dated May 20, 1999, by and between Immunex and
     Parent.

          Exhibit VII - Note ($450 million, 3% Convertible Subordinated Note due
     2006), dated May 20, 1999, issued by Immunex to Parent.

          Exhibit VIII - Amendment, dated May 20, 1999, by and among Parent, ACY
     and Immunex, to the Governance Agreement.




                               IMMUNEX CORPORATION



                                  $450,000,000

                    3% Convertible Subordinated Note due 2006



                             NOTE PURCHASE AGREEMENT



                            Dated as of May 20, 1999



<PAGE>

                               Immunex Corporation
                              51 University Street
                            Seattle, Washington 98101

                                                  As of May 20, 1999

American Home Products Corporation
Five Giralda Farms
Madison, New Jersey  07940

Ladies and Gentlemen:

     The undersigned, Immunex Corporation (together with any Person who succeeds
to all or substantially all of Immunex Corporation's assets and business, herein
called the "Company"), a Washington corporation, hereby agrees with American
Home Products Corporation (the "Purchaser") as follows:

     1. Authorization of Issue of Note

     The Company will authorize the issue and sale of a $450,000,000 principal
amount 3% Convertible Subordinated Note due 2006 (the "Note," such term to
include the Note or Notes delivered pursuant to this Agreement and any such
Notes issued in substitution therefor).

     The Note shall be substantially in the form of Exhibit A, with such changes
therefrom, if any, as may be approved by the Purchaser and the Company. Certain
capitalized terms used in this Agreement are defined in Exhibit B; references to
a "Schedule" or an "Exhibit" are, unless otherwise specified, to a Schedule or
an Exhibit attached to this Agreement and references to "this Agreement" shall
mean this Agreement as it may from time to time be amended or supplemented.

     2. The Closing

     The sale and purchase of the Note shall occur at the offices of Perkins
Coie LLP, 1201 Third Avenue, Seattle, Washington 98101 at 12 noon Seattle time,
at the closing (the "Closing") on May 20, 1999 or on such other Business Day
thereafter on or prior to May 30, 1999 as may be agreed upon by the Purchaser
and the Company. At the Closing, the Company will deliver to the Purchaser the
Note dated the date of the Closing and registered to American Home Products
Corporation, against delivery to the Company on its order of immediately
available funds in the amount of the purchase price by wire transfer of
immediately available funds for the account of the Company to account number
153500075822 at U.S. Bank of Washington, N.A., ABA#125000105.

     3. Conditions to Closing

     The Purchaser's obligation to purchase and pay for the Note at the Closing
is subject to the fulfillment to the Purchaser's satisfaction, prior to or at
the Closing, of the following conditions:

     3.1 Representations and Warranties

     The representations and warranties of the Company in this Agreement shall
be correct when made and at the time of the Closing.

     3.2 Performance; No Default

     The Company shall have performed and complied with all covenants contained
in this Agreement required to be performed or complied with by it prior to or at
the Closing, and after giving effect to the issue and sale of the Note, no
Default or Event of Default shall have occurred or be continuing.

     3.3 Opinion of Counsel

     The Purchaser shall have received an opinion from Perkins Coie LLP, counsel
to the Company, substantially in the form of Exhibit C.

     4 Representations and Warranties of the Company

     The Company represents and warrants:

     4.1 Organization

     (a) The Company is a corporation organized and existing under the laws of
the state of Washington and is qualified or licensed to do business (and is in
good standing as a foreign corporation, as applicable) in all jurisdictions in
which the failure to so qualify or to be so licensed could reasonably be
expected to have a Material Adverse Effect. The Company has the requisite
corporate power and authority to own and operate its properties, to conduct its
business as currently conducted, to enter into this Agreement, to issue and sell
the Note and to carry out the terms of this Agreement and the Note.

     (b) The Company has no Subsidiaries other than Immunex Manufacturing Corp.,
a corporation organized and existing under the laws of the state of Washington
("IMC"). IMC is qualified or licensed to do business (and is in good standing as
a foreign corporation, as applicable) in all jurisdictions in which the failure
to so qualify or to be so licensed could reasonably be expected to have a
Material Adverse Effect. IMC has the requisite corporate power and authority to
own and operate its properties and to conduct its business as currently
conducted.

     4.2 Capitalization

     (a) As of April 30, 1999, the authorized capital stock of the Company
consisted of (i) 200,000,000 shares of common stock, par value $0.01 per share
("Common Stock"), of which (A) 81,365,178 shares were issued and outstanding,
(B) 11,182,906 shares were reserved for issuance upon exercise of stock options
under the Immunex Corporation Amended and Restated 1993 Stock Option Plan and
(C) 180,000 shares were reserved for issuance upon exercise of options under the
Immunex Corporation Stock Option Plan for Nonemployee Directors, and (ii)
5,000,000 shares of preferred stock, par value $0.01 per share ("Preferred
Stock"), which have not yet been issued or designated as to a series by the
Board of Directors. As of the date hereof, of the 200,000,000 shares of
authorized Common Stock, (i) 6,000,000 additional shares are reserved for
issuance upon exercise of options under the Immunex Corporation 1999 Stock
Option Plan and (ii) 500,000 additional shares are reserved for issuance upon
purchase under the Immunex Corporation Employee Stock Purchase Plan.

     (b) The equity securities of IMC that are issued and outstanding are duly
authorized and validly issued, fully paid and nonassessable, and issued in
compliance with all applicable federal, state and foreign securities laws. The
Company is the record and beneficial owner of all of the outstanding shares of
capital stock of IMC.

     (c) All shares of Common Stock and Preferred Stock that are issued and
outstanding are duly authorized and validly issued, fully paid and
nonassessable, and issued in compliance with all applicable federal, state and
foreign securities laws.

     (d) Other than as provided for herein, there are no outstanding rights of
first refusal, preemptive rights, options, warrants, conversion rights or other
agreements, either directly or indirectly, for the purchase or acquisition from
the Company or IMC of any shares of capital stock of the Company or IMC, as the
case may be.

     (e) The shares of Common Stock issuable on the conversion of the Note, as
provided herein, have been duly and validly reserved for issuance and, upon
issuance in accordance with the terms of this Agreement and the Note, will be
validly issued, fully paid and nonassessable, and issued in compliance with all
applicable federal, state and foreign securities laws. 4.3 Authorization

     This Agreement and the Note have been duly authorized by all requisite
corporate action on the part of the Company, and this Agreement and the Note
constitute legal, valid and binding obligations of the Company enforceable
against the Company in accordance with their terms, except as such
enforceability may be limited by (a) applicable bankruptcy, insolvency,
reorganization, moratorium or other similar laws affecting the enforcement of
creditor's laws generally and (b) general principles of equity (regardless of
whether such enforceability is considered in a proceeding in equity or at law).

     4.4 No Conflicts

     The execution, delivery and performance of this Agreement and the Note by
the Company, and the consummation of the transactions contemplated hereby and
thereby, will not violate any existing provision of law or statute or order of
any court or other agency of government, or conflict with or result in any
breach of any of the terms, conditions or provisions of, or constitute (with due
notice or lapse of time or both) a default under, or result in the creation of
any material lien, security interest, charge or encumbrance upon any of the
properties or assets of the Company or IMC under (a) the articles of
incorporation or bylaws of the Company or IMC or (b) any indenture or mortgage,
or material lease, agreement or other instrument to which the Company or IMC is
a party or by which they or any of their respective properties property is bound
or affected.

     4.5 No Defaults

     The Company is not in default (a) under its Restated Articles of
Incorporation or its Bylaws; (b) under any material contract, agreement or
instrument to which the Company is a party or by which it or any of its property
is bound or affected, including without limitation any material indenture,
mortgage, lease, license or purchase or sales order; or (c) with respect to any
statute, order, rule or regulation, writ, injunction or decree of any court or
of any federal, state, municipal or other domestic or foreign governmental
department, commission, board, bureau, agency or instrumentality. To the
knowledge of the Company, there presently exists no material default by any
party other than the Company to any of the foregoing, and no condition, event or
act which constitutes, or which after notice, lapse of time or both would
constitute, a material default by the Company or any other party under any of
the foregoing.

     4.6 SEC Filings

     The Company has filed with the Securities and Exchange Commission (the
"SEC") all forms, reports and documents required to be filed with the SEC by the
Company pursuant to the Exchange Act since December 31, 1997 (collectively, the
"Company SEC Reports"). The Company SEC Reports (a) comply in all material
respects with the applicable requirements of the Exchange Act, and (b) do not
contain any untrue statement of a material fact or omit to state a material fact
required to be stated therein or necessary in order to make the statements
therein, in the light of the circumstances under which they were made, not
misleading. The annual financial statements and schedules included in the
Company SEC Reports have been prepared in accordance with generally accepted
accounting principles applied on a consistent basis throughout the periods
specified and present fairly the financial position for the dates specified, and
the results of their operations and cash flows of the Company for the respective
periods specified. The quarterly financial statements and schedules included in
the Company SEC Reports present fairly the financial position for the dates
specified and the results of operations for the quarterly periods presented and
are presented on a basis consistent with the audited financial statements.

     4.7 Absence of Changes

     Except as contemplated by this Agreement or disclosed in the Company SEC
Reports, subsequent to December 31, 1998, (a) the Company has not incurred any
material liabilities or obligations, direct or contingent, or entered into any
material transactions not in the ordinary course of business, and (b) there has
not been any change in the condition (financial or otherwise), business,
properties or results of operations of the Company which could reasonably be
expected to have a Material Adverse Effect.

     4.8 Tax Returns and Payments

     The Company has filed all federal, state and foreign income and franchise
tax returns required by law to be filed by it (or obtained extensions with
respect thereto) and has paid all material taxes, assessments and other material
governmental charges which are due and payable by it, other than those which are
not past due or delinquent or the nonpayment of which is permitted by Section
6.5.

     4.9 Governmental Consent

     No consent, approval or authorization of, or declaration or filing with,
any governmental authority is required for the valid execution, delivery and
performance by the Company of this Agreement or the valid offer, issue, sale and
delivery of the Note pursuant to this Agreement or the conversion of the Note
into shares of Common Stock.

     4.10 Claims and Legal Proceedings

     There are no claims, actions, suits, arbitrations, criminal or civil
investigations or proceedings pending or involving or, to the knowledge of the
Company, threatened against the Company or IMC before or by any court or
governmental or nongovernmental department, commission, board, bureau, agency or
instrumentality, or any other Person. To the knowledge of the Company, there is
no valid basis for any claim, action, suit, arbitration, investigation or
proceeding involving the Company or IMC that could reasonably be expected to
have a Material Adverse Effect. There are no outstanding or unsatisfied
judgments, orders, decrees or stipulations to which the Company or IMC is a
party that involve the transactions contemplated herein or that could reasonably
be expected to have a Material Adverse Effect.

     4.11 Title to Property and Assets

     The Company and IMC have good and marketable title to their respective
properties and assets and own such property and assets free and clear of all
mortgages, liens, loans and encumbrances, except such encumbrances and liens
which arise in the ordinary course of business and do not materially impair the
Company's or IMC's ownership or use of such property or assets. With respect to
the property and assets they lease, each of the Company and IMC is in compliance
with such leases and, to the Company's knowledge, holds a valid leasehold
interest free of any liens, claims or encumbrances. No event has occurred and is
continuing which, with due notice or lapse of time or both, would constitute a
default or event of default by the Company or IMC, as the case may be, under any
such lease or agreement or, to the Company's knowledge, by any other Person. The
Company's and IMC's respective possession of such property has not been
disturbed and, to the Company's knowledge, no claim has been asserted against
the Company or IMC adverse to their respective rights in such leasehold
interests.

     4.12 Licenses, Permits, Authorizations, etc.

     The Company and IMC have received all required governmental approvals,
authorizations, consents, licenses, orders, registrations and permits of all
agencies, whether federal, state, local or foreign (the "Permits"), the failure
to obtain of which would have a Material Adverse Effect. The Company and IMC are
in compliance with the terms of all Permits, and all Permits are valid and in
full force and effect, and no proceeding is pending or, to the knowledge of the
Company, threatened, the object of which is to revoke, limit or otherwise affect
any Permit. Neither the Company nor IMC has received any notifications of any
asserted failure to obtain any Permit.

     4.13 Environmental Laws

     To the Company's knowledge, neither the Company nor IMC is in violation of
any applicable statute, law or regulation relating to the environment, and to
the Company's knowledge, no material expenditures are or will be required in
order to comply with any such existing statute, law or regulation.

     4.14 Intellectual Property

     (a) To the Company's knowledge, the Company and IMC have sufficient title
to and ownership of or rights to use all patents, patent applications, trade
names, trademarks, trademark applications, trade dress, service marks,
copyright, trade secrets, information, proprietary rights and processes
("Intellectual Property") necessary for their respective businesses as now
conducted, or as proposed to be conducted, without any conflict with or
infringement of the rights of others.

     (b) The Company is not aware, after due inquiry, that any of its or IMC's
employees are obligated under any contract (including licenses, covenants or
commitments of any nature) or other agreement, or subject to any judgment,
decree or order of any court or administrative agency, that would interfere with
the use of such employee's best efforts to promote the interests of the Company
or IMC or that would conflict with the Company's or IMC's business as proposed
to be conducted. Neither the execution nor delivery of this Agreement or the
Note, nor the carrying on of the Company's or IMC's business by the employees of
and consultants to the Company or IMC, as the case may be, nor the conduct of
the Company's or IMC's business as proposed, will, to the Company's knowledge,
conflict with or result in a breach of the terms, conditions or provisions of,
or constitute a default under, any contract, covenant or instrument under which
any of such employees or consultants is now obligated.

     (c) Since their respective organization, each of the Company and IMC has
taken reasonable measures to protect the value (and, to the extent applicable,
the confidentiality and security) of all Intellectual Property used in their
respective products, services and business. Each of the Company's and IMC's
employees who, either alone or in concert with others, developed, invented,
discovered, derived, programmed or designed Intellectual Property or Inventions
(as defined below), or who has knowledge of or access to information about
Intellectual Property or Inventions, has entered into confidentiality,
inventions and noncompetition agreements with the Company or IMC, as the case
may be. "Inventions" means all inventions, developments and discoveries which
during the period of an employee's service to the Company or IMC, as the case
may be, he or she makes or conceives of, either solely or jointly with others,
that relate to any subject matter with which his or her work for the Company or
IMC may be concerned, or relate to or are connected with the business, products,
services or projects of the Company or IMC, or relate to the actual or
demonstrably anticipated research or development of the Company or IMC or
involve the use of the Company's or IMC's funds, time, material, facilities or
trade secret information, except as excluded pursuant to applicable law. No
exceptions have been taken by any such employee to the terms of his or her
confidentiality, inventions and noncompetition agreement with the Company or
IMC. The Company, after reasonable investigation, is not aware that any of its
or IMC's employees is in violation thereof, and the Company will use
commercially reasonable efforts to prevent, and to cause IMC to prevent, any
such violation.

     (d) Except as set forth in the Company SEC Reports, (i) no claim has been
made (whether written, oral or otherwise) challenging the Company's or IMC's
ownership or rights in any Intellectual Property or claiming that any other
Person has any legal or beneficial ownership with respect thereto; (ii) no claim
has been made (whether written, oral or otherwise) challenging the validity or
enforceability of any material item of the Intellectual Property; and (iii) to
the Company's knowledge, no other Person is infringing or misappropriating any
part of the Intellectual Property or otherwise making any unauthorized use of
the Intellectual Property, except, in each such case, where such action could
not reasonably be expected to result in a Material Adverse Effect.

     4.15 Employee Arrangements and Plans

     The Company is in full compliance with the Employee Retirement Income
Security Act of 1974, as amended, and the rules and regulations promulgated
thereunder, except for any failure to comply which will not result in a Material
Adverse Effect.

     5. Representations of the Purchaser

     The Purchaser represents, and in issuing the Note to the Purchaser it is
expressly understood and agreed between the Company and the Purchaser, that the
Purchaser is not acquiring the Note hereunder with a view to or for sale in
connection with any distribution thereof within the meaning of the Securities
Act. The Purchaser understands that the Note has not been registered under the
Securities Act and may be resold only if registered pursuant to the provisions
of the Securities Act or if an exemption from registration is available, except
under circumstances where neither such registration nor such an exemption is
required by law, and that the Company is not required to register the Note.

     6. Particular Covenants of the Company

     6.1 Payment of Principal and Interest

     The Company covenants and agrees that it will duly and punctually pay or
cause to be paid the principal of and premium, if any, and interest on the Note
at the places, at the respective times and in the manner provided herein and in
the Note.

     6.2 Maintenance of Office or Agency.

     The Company will maintain an office or agency where the Note may be
surrendered for registration of transfer or exchange or for presentation for
payment or for conversion or redemption and where notices and demands to or upon
the Company in respect of the Note and this Agreement may be served. The Company
will give prompt notice of any change in the location of such office or agency.

     The Company may also from time to time designate a trustee, co-registrars
and one or more offices or agencies where the Note may be presented or
surrendered for any or all such purposes and may from time to time rescind such
designations. The Company will give prompt written notice of any such
designation or rescission and of any change in the location of any such other
office or agency.

     The Company hereby initially designates itself as paying agent, Note
registrar, Custodian and conversion agent and its principal executive offices at
51 University Street, Seattle, Washington as the office or agency of the Company
for each of the aforesaid purposes.

     6.3 Existence

     The Company will do or cause to be done all things necessary to preserve
and keep in full force and effect its existence and rights (charter and
statutory); provided, however, that the Company shall not be required to
preserve any such right if the Company shall determine that the preservation
thereof is no longer desirable in the conduct of the business of the Company and
that the loss thereof is not disadvantageous in any material respect to the
Purchaser.

     6.4 Maintenance of Properties

     The Company will cause all properties used or useful in the conduct of its
business or the business of any Subsidiary to be maintained and kept in good
condition, repair and working order and supplied with all necessary equipment
and will cause to be made all necessary repairs, renewals, replacements,
betterments and improvements thereof, all as in the judgment of the Company may
be necessary so that the business carried on in connection therewith may be
properly and advantageously conducted at all times; provided, however, that
nothing in this Section 6.4 shall prevent the Company from discontinuing the
operation or maintenance of any of such properties if such discontinuance is, in
the judgment of the Company, desirable in the conduct of its business or the
business of any Subsidiary and not disadvantageous in any material respect to
the Purchaser.

     6.5 Payment of Taxes and Other Claims

     The Company will pay or discharge, or cause to be paid or discharged,
before the same may become delinquent, (a) all taxes, assessments and
governmental charges levied or imposed upon the Company or any Significant
Subsidiary or upon the income, profits or property of the Company or any
Significant Subsidiary, (b) all claims for labor, materials and supplies which,
if unpaid, might by law become a lien or charge upon the property of the Company
and (c) all stamps and other duties, if any, which may be imposed by the United
States or any political subdivision thereof or therein in connection with the
issuance, transfer, exchange or conversion of the Note or with respect to this
Agreement; provided, however, that, in the case of clauses (a) and (b), the
Company shall not be required to pay or discharge or cause to be paid or
discharged any such tax, assessment, charge or claim (x) if the failure to do so
will not, in the aggregate, have a Material Adverse Effect on the Company or (y)
if the amount, applicability or validity is being contested in good faith by
appropriate proceedings with appropriate reserves reflected on the Company's
financial statements.

     6.6 Rule 144A Information Requirement

     The Company covenants and agrees that it shall, during any period in which
it is not subject to Section 13 or 15(d) under the Exchange Act, make available
to the Purchaser, the information required pursuant to Rule 144A(d)(4) under the
Securities Act upon the Purchaser's request and it will take such further action
as the Purchaser may reasonably request, all to the extent required from time to
time to enable the Purchaser to sell the Note or Common Stock into which the
Note is convertible without registration under the Securities Act within the
limitation of the exemption provided by Rule 144A, as such Rule may be amended
from time to time. Upon the Purchaser's request, the Company will deliver to
such holder a written statement as to whether it has complied with such
requirements.

     6.7 Stay, Extension and Usury Laws

     The Company covenants (to the extent that it may lawfully do so) that it
shall not at any time insist upon, plead, or in any manner whatsoever claim or
take the benefit or advantage of, any stay, extension or usury law or other law
which would prohibit or forgive the Company from paying all or any portion of
the principal of, premium, if any, or interest on the Note as contemplated
herein, wherever enacted, now or at any time hereafter in force, or which may
affect the covenants or the performance of this Agreement, and the Company (to
the extent it may lawfully do so) hereby expressly waives all benefit or
advantage of any such law.

     6.8 Indenture

     If reasonably requested by the Purchaser, the Company shall prepare and
execute within sixty (60) days of such request an indenture consistent with
indentures executed in transactions similar to issuance and sale of the Note and
reasonably satisfactory to the Purchaser.

     6.9 Use of Proceeds

     The proceeds of the sale of the Note shall be used to fund the acquisition
of additional assets of the Company as may be approved from time to time by the
Company's Board of Directors pursuant to the terms of the Amended and Restated
Governance Agreement dated as of December 15, 1992 among the Company, American
Cyanamid Company and Lederle Oncology Corporation. Pending such use, the
proceeds from the sale of the Note shall be invested by the Company in income
securities of a duration and quality consistent with the Company's investment
guidelines in effect as of the date hereof (or as may be changed with the
consent of Purchaser).

     7. Immunity of Incorporators, Shareholders, Officer and Directors

     No recourse for the payment of the principal of or premium, if any, or
interest on the Note, or for any claim based thereon or otherwise in respect
thereof, and no recourse under or upon any obligation, covenant or agreement of
the Company in this Agreement or in the Note, or because of the creation of any
indebtedness represented thereby, shall be had against any incorporator,
shareholder, employee, agent, officer, director or subsidiary, as such, past,
present or future, of the Company or of any successor corporation, either
directly or through the Company or any successor corporation, whether by virtue
of any constitution, statute or rule of law, or by the enforcement of any
assessment or penalty or otherwise; it being expressly understood that all such
liability is hereby expressly waived and released as a condition of, and as a
consideration for, the execution of this Agreement and the issue of the Note.

     8. Conversion Of Note

     8.1 Right to Convert.

     Subject to and upon compliance with the provisions of this Agreement, the
Purchaser shall have the right, at its sole option, at any time and from time to
time after the Closing through the close of business on the final maturity date
of the Note to convert the principal amount of the Note or any portion thereof,
in an amount of at least Fifty Million Dollars ($50,000,000), and in increments
of One Million Dollar ($1,000,000) in excess thereof, into that number of fully
paid and non-assessable shares of Common Stock (as such shares shall then be
constituted after giving effect to any appropriate adjustments) obtained by
dividing the principal amount of the Note, or portion thereof surrendered for
conversion, by the Conversion Price in effect at such time, by surrender of the
Note to be converted in whole or in part in the manner provided in Section 8.2.
Except as otherwise provided herein or in the Governance Agreement or the
Product Rights Agreement, the Purchaser is not entitled to any rights of a
holder of Common Stock until it has converted the Note to Common Stock, and only
to the extent the Note is deemed to have been converted to Common Stock under
this Section 8.

     8.2  Exercise  of  Conversion  Privilege;   Issuance  of  Common  Stock  on
Conversion; No Adjustment for Interest or Dividends

     In order to exercise the conversion privilege, the Purchaser shall
surrender the Note, duly endorsed, at an office or agency maintained by the
Company pursuant to Section 6.2, and shall give written notice of conversion in
the form provided on the Note (or such other notice that is acceptable to the
Company) that the Purchaser elects to convert the Note or the portion thereof
specified in such notice. Such notice shall also state the name or names (with
addresses) in which the certificates for shares of Common Stock that shall be
issuable upon such conversion shall be issued, and shall be accompanied by
transfer taxes if required pursuant to Section 8.7. Unless the shares issuable
upon conversion of the Note are to be issued in the name of the Purchaser, the
Note shall be duly endorsed in each case by the Purchaser or be accompanied by
instruments of transfer duly executed by the Purchaser in form satisfactory to
the Company.

     As promptly as practicable after satisfaction of the requirements for
conversion set forth above, subject to compliance with any restrictions on
transfer, the Company shall issue and shall deliver to the Purchaser or the then
holder of the Note (or portion thereof) at the office or agency maintained by
the Company for such purpose pursuant to Section 6.2, a certificate or
certificates for the number of full shares of Common Stock issuable upon the
conversion of the Note or portion thereof in accordance with the provisions of
this Section 8 and a check or cash in respect of (a) any fractional interest in
respect of a share of Common Stock arising upon such conversion and (b) accrued
and unpaid interest, if any, to, but excluding, the date of such conversion, all
as provided in Section 8.3. In case the Note is surrendered for partial
conversion, the Company shall execute and deliver to the Purchaser, without
charge to it, a new Note or Notes in authorized denominations in an aggregate
principal amount equal to the unconverted portion of the surrendered Note.

     Each conversion shall be deemed to have been effected as to the Note (or
portion thereof) on the date on which the requirements set forth above in this
Section 8.2 have been satisfied as to the Note (or portion thereof), and the
Person in whose name any certificate or certificates for shares of Common Stock
shall be issuable upon such conversion shall be deemed to have become on such
date the holder of record of the shares represented thereby; provided, however,
that in the event of any such surrender on any date when the stock transfer
books of the Company shall be closed, the Person in whose name the certificates
are to be issued shall constitute the record holder thereof for all purposes on
the next succeeding day on which such stock transfer books are open, but such
conversion shall be at the Conversion Price in effect on the date upon which the
Note shall be surrendered.

     8.3 Cash Payments in Lieu of Fractional Shares; Payment of Accrued Interest

     No fractional shares of Common Stock or scrip representing fractional
shares shall be issued upon conversion of the Note. If a Note shall be
surrendered for conversion, the number of full shares that shall be issuable
upon conversion shall be computed on the basis of the aggregate principal amount
of the Note (or specified portions thereof to the extent permitted thereby), so
surrendered. If any fractional share of stock would be issuable upon the
conversion of the Note, the Company shall make an adjustment and payment
therefor in cash at the current market price thereof to the Purchaser or any
holder thereof. The current market price of a share of Common Stock shall be the
Closing Price on the last Business Day immediately preceding the day on which
the Note (or specified portions thereof) is deemed to have been converted. If a
Note shall be surrendered for conversion pursuant to this Section 8, the Company
shall make an additional payment in a check or cash to the Purchaser or holder
thereof for accrued and unpaid interest, if any, to, but excluding, the date of
such conversion.

     8.4 Conversion Price

     The conversion price shall be as specified in the form of Note (herein
called the "Conversion Price") attached as Exhibit A hereto, subject to
adjustment as provided in this Section 8. References to the Conversion Price
contained herein shall mean the same as so adjusted from time to time pursuant
to Section 8.5 hereof.

     8.5 Adjustment of Conversion Price

     The Conversion Price shall be adjusted from time to time by the Company as
follows:

     (a) In case the Company shall hereafter pay a dividend or make a
distribution to all holders of the outstanding Common Stock in shares of Common
Stock, the Conversion Price in effect at the opening of business on the date
following the date fixed for the determination of shareholders entitled to
receive such dividend or other distribution shall be reduced by multiplying such
Conversion Price by a fraction, (i) the numerator of which shall be the number
of shares of the Common Stock outstanding at the close of business on the date
fixed for such determination and (ii) the denominator of which shall be the sum
of such number of shares and the total number of shares constituting such
dividend or other distribution, such reduction to become effective immediately
after the opening of business on the day following the date fixed for such
determination. If any dividend or distribution of the type described in this
Section 8.5(a) is declared but not so paid or made, the Conversion Price shall
again be adjusted to the Conversion Price that would then be in effect if such
dividend or distribution had not been declared.

     (b) In case the Company shall issue rights or warrants to all holders of
its outstanding shares of Common Stock entitling them to subscribe for or
purchase shares of Common Stock at a price per share less than the Current
Market Price (as defined below), on the date fixed for determination of
shareholders entitled to receive such rights or warrants the Conversion Price
shall be adjusted so that the same shall equal the price determined by
multiplying the Conversion Price in effect immediately prior to the date fixed
for determination of shareholders entitled to receive such rights or warrants by
a fraction, (i) the numerator of which shall be (A) the number of shares of
Common Stock outstanding at the close of business on the date fixed for
determination of shareholders entitled to receive such rights or warrants plus
(B) the number of shares of Common Stock that the aggregate offering price of
the total number of shares so offered would purchase at such Current Market
Price, and (ii) the denominator of which shall be (A) the number of shares of
Common Stock outstanding on the date fixed for determination of shareholders
entitled to receive such rights and warrants plus (B) the total number of
additional shares of Common Stock offered for subscription or purchase. Such
adjustment shall be successively made whenever any such rights or warrants are
issued, and shall become effective immediately after the opening of business on
the day following the date fixed for determination of shareholders entitled to
receive such rights or warrants. To the extent that shares of Common Stock are
not delivered after the expiration of such rights or warrants, the Conversion
Price shall be readjusted to the Conversion Price that would then be in effect
had the adjustments made upon the issuance of such rights or warrants been made
on the basis of delivery of only the number of shares of Common Stock actually
delivered. In the event that such rights or warrants are not so issued, the
Conversion Price shall again be adjusted to be the Conversion Price that would
then be in effect if such date fixed for the determination of shareholders
entitled to receive such non-issued rights or warrants had not been fixed. In
determining whether any rights or warrants entitle the holders to subscribe for
or purchase shares of Common Stock at less than such Current Market Price, and
in determining the aggregate offering price of such shares of Common Stock,
there shall be taken into account any consideration received by the Company for
such rights or warrants, the value of such consideration, if other than cash, to
be conclusively determined by the Board of Directors.

     (c) In case outstanding shares of Common Stock shall be subdivided into a
greater number of shares of Common Stock, the Conversion Price in effect at the
opening of business on the day following the day upon which such subdivision
becomes effective shall be proportionately reduced, and conversely, in case
outstanding shares of Common Stock shall be combined into a smaller number of
shares of Common Stock, the Conversion Price in effect at the opening of
business on the day following the day upon which such combination becomes
effective shall be proportionately increased, such reduction or increase, as the
case may be, to become effective immediately after the opening of business on
the day following the day upon which such subdivision or combination becomes
effective.

     (d) In case the Company shall, by dividend or otherwise, distribute to all
holders of its Common Stock shares of any class of capital stock of the Company
(other than any dividends or distributions to which Section 8.5(a) applies) or
evidences of its indebtedness or assets or rights or warrants to subscribe for
or purchase any of its securities (including securities, but excluding any
rights or warrants referred to in Section 8.5(b), and excluding any dividend or
distribution (x) paid exclusively in cash from retained earnings or current
earnings or (y) referred to in Section 8.5(a)), any of the foregoing hereinafter
in this Section 8.5(d) called the "Securities," then, in each such case (unless
the Company elects to reserve such Securities for distribution to the Purchaser
upon the conversion of the Note so that the Purchaser will receive upon such
conversion, in addition to the shares of Common Stock to which it is entitled,
the amount and kind of such Securities which it would have received if it had
converted the Note into Common Stock immediately prior to the Record Date (as
defined in Section 8.5(i)), for such distribution of the Securities), the
Conversion Price shall be reduced so that the same shall be equal to the price
determined by multiplying the Conversion Price in effect on the Record Date with
respect to such distribution by a fraction, (i) the numerator of which shall be
(A) the Current Market Price per share of the Common Stock on such Record Date
less (B) the fair market value (as determined by the Board of Directors, whose
determination shall be conclusive and described in a resolution of the Board of
Directors) on the Record Date of the portion of the Securities so distributed
applicable to one share of Common Stock, and (ii) the denominator of which shall
be the Current Market Price per share of the Common Stock, such reduction to
become effective immediately prior to the opening of business on the day
following such Record Date; provided, however, that in the event the then fair
market value (as so determined) of the portion of the Securities so distributed
applicable to one share of Common Stock is equal to or greater than the Current
Market Price of the Common Stock on the Record Date, in lieu of the foregoing
adjustment, adequate provision shall be made so that the Purchaser shall have
the right to receive upon conversion the amount of Securities such holder would
have received had such holder converted each Note on the Record Date. In the
event that such dividend or distribution is not so paid or made, the Conversion
Price shall again be adjusted to be the Conversion Price that would then be in
effect if such dividend or distribution had not been declared. If the Board of
Directors determines the fair market value of any distribution for purposes of
this Section 8.5(d) by reference to the actual or when issued trading market for
any securities, it must in doing so consider the prices in such market over the
same period used in computing the Current Market Price of the Common Stock.

     Rights or warrants distributed by the Company to all holders of Common
Stock entitling the holders thereof to subscribe for or purchase shares of the
Company's capital stock, which rights or warrants, until the occurrence of a
specified event or events ("Trigger Event"): (i) are deemed to be transferred
with such shares of Common Stock; (ii) are not exercisable; and (iii) are also
issued in respect of future issuances of Common Stock, shall be deemed not to
have been distributed for purposes of this Section 8.5 (and no adjustment to the
Conversion Price under this Section 8.5 will be required) until the occurrence
of the earliest Trigger Event, whereupon such rights and warrants shall be
deemed to have been distributed and an appropriate adjustment (if any is
required) to the Conversion Price shall be made under this Section 8.5(d). If
any such right or warrant, including any such existing rights or warrants
distributed prior to the date of this Agreement, are subject to events, upon the
occurrence of which such rights or warrants become exercisable to purchase
different securities, evidences of indebtedness or other assets, then the date
of the occurrence of any and each such event shall be deemed to be the date of
distribution and record date with respect to new rights or warrants with such
rights (and a termination or expiration of the existing rights or warrants
without exercise by any of the holders thereof). In addition, in the event of
any distribution (or deemed distribution) of rights or warrants, or any Trigger
Event or other event (of the type described in the preceding sentence) with
respect thereto that was counted for purposes of calculating a distribution
amount for which an adjustment to the Conversion Price under this Section 8.5
was made, (i) in the case of any such rights or warrants that shall all have
been redeemed or repurchased without exercise by any holders thereof, the
Conversion Price shall be readjusted upon such final redemption or repurchase to
give effect to such distribution or Trigger Event, as the case may be, as though
it were a cash distribution, equal to the per share redemption or repurchase
price received by a holder or holders of Common Stock with respect to such
rights or warrants (assuming such holder had retained such rights or warrants),
made to all holders of Common Stock as of the date of such redemption or
repurchase, and (ii) in the case of such rights or warrants that shall have
expired or been terminated without exercise by any holders thereof, the
Conversion Price shall be readjusted as if such rights and warrants had not been
issued.

     For purposes of this Section 8.5(d) and Sections 8.5(a) and (b), any
dividend or distribution to which this Section 8.5(d) is applicable that also
includes shares of Common Stock, or rights or warrants to subscribe for or
purchase shares of Common Stock (or both), shall be deemed instead to be (i) a
dividend or distribution of the evidences of indebtedness, assets or shares of
capital stock other than such shares of Common Stock or rights or warrants (and
any Conversion Price reduction required by this Section 8.5(d) with respect to
such dividend or distribution shall then be made) immediately followed by (ii) a
dividend or distribution of such shares of Common Stock or such rights or
warrants (and any further Conversion Price reduction required by Sections 8.5(a)
and (b) with respect to such dividend or distribution shall then be made),
except (A) the Record Date of such dividend or distribution shall be substituted
as "the date fixed for the determination of shareholders entitled to receive
such dividend or other distribution" and "the date fixed for such determination"
within the meaning of Sections 8.5(a) and (b), and (B) any shares of Common
Stock included in such dividend or distribution shall not be deemed "outstanding
at the close of business on the date fixed for such determination" within the
meaning of Section 8.5(a).

     (e) In case the Company shall, by dividend, tender offer, exchange offer or
otherwise, distribute to all holders of its Common Stock cash, then, in such
case, the Conversion Price shall be reduced so that the same shall equal the
price determined by multiplying the Conversion Price in effect immediately prior
to the close of business on such Record Date by a fraction, (ii) the numerator
of which shall be (A) the Current Market Price of the Common Stock on the Record
Date less (B) the amount of cash so distributed (and not excluded as provided
above) applicable to one share of Common Stock, and (ii) the denominator of
which shall be such Current Market Price of the Common Stock, such reduction to
be effective immediately prior to the opening of business on the day following
the Record Date; provided, however, that in the event the portion of the cash so
distributed applicable to one share of Common Stock is equal to or greater than
the Current Market Price of the Common Stock on the Record Date, in lieu of the
foregoing adjustment, adequate provision shall be made so that the Purchaser
shall have the right to receive upon conversion the amount of cash the Purchaser
would have received had it converted the Note on the Record Date. In the event
that such dividend or distribution is not so paid or made, the Conversion Price
shall again be adjusted to be the Conversion Price that would then be in effect
if such dividend or distribution had not been declared. If any adjustment is
required to be made as set forth in this Section 8.5(e) as a result of a
distribution that is a quarterly dividend, such adjustment shall be based upon
the amount by which such distribution exceeds the amount of the quarterly cash
dividend permitted to be excluded pursuant hereto. If an adjustment is required
to be made as set forth in this Section 8.5(e) above as a result of a
distribution that is not a quarterly dividend, such adjustment shall be based
upon the full amount of the distribution.

     (f) In case a tender or exchange offer made by the Company or any
Subsidiary for all or any portion of the Common Stock shall expire and such
tender or exchange offer (as amended upon the expiration thereof) shall require
the payment to shareholders of consideration per share of Common Stock having a
fair market value (as determined by the Board of Directors, whose determination
shall be conclusive and described in a resolution of the Board of Directors)
that as of the last time (the "Expiration Time") tenders or exchanges may be
made pursuant to such tender or exchange offer (as it may be amended) exceeds
the Current Market Price of the Common Stock on the Trading Day next succeeding
the Expiration Time, the Conversion Price shall be reduced so that the same
shall equal the price determined by multiplying the Conversion Price in effect
immediately prior to the Expiration Time by a fraction, (i) the numerator of
which shall be (A) the number of shares of Common Stock outstanding (including
any tendered or exchanged shares) on the Expiration Time multiplied by (B) the
Current Market Price of the Common Stock on the Trading Day next succeeding the
Expiration Time, and (ii) the denominator of which shall be the sum of (A) the
fair market value (determined as aforesaid) of the aggregate consideration
payable to shareholders based on the acceptance (up to any maximum specified in
the terms of the tender or exchange offer) of all shares validly tendered or
exchanged and not withdrawn as of the Expiration Time (the shares deemed so
accepted, up to any such maximum, being referred to as the "Purchased Shares")
and (B) the product of (x) the number of shares of Common Stock outstanding
(less any Purchased Shares) on the Expiration Time and (y) the Current Market
Price of the Common Stock on the Trading Day next succeeding the Expiration
Time, such reduction to become effective immediately prior to the opening of
business on the day following the Expiration Time. In the event that the Company
is obligated to purchase shares pursuant to any such tender or exchange offer,
but the Company is permanently prevented by applicable law from effecting any
such purchases or all such purchases are rescinded, the Conversion Price shall
again be adjusted to be the Conversion Price that would then be in effect if
such tender or exchange offer had not been made.

     (g) In case of a tender or exchange offer made by a Person other than the
Company or any Subsidiary for an amount that increases the offeror's ownership
of Common Stock to more than twenty-five percent (25%) of the Common Stock
outstanding and shall involve the payment by such Person of consideration per
share of Common Stock having a fair market value (as determined by the Board of
Directors, whose determination shall be conclusive, and described in a
resolution of the Board of Directors) at the last time (the "Offer Expiration
Time") tenders or exchanges may be made pursuant to such tender or exchange
offer (as it shall have been amended) that exceeds the Current Market Price of
the Common Stock on the Trading Day next succeeding the Offer Expiration Time,
and in which, as of the Offer Expiration Time the Board of Directors is not
recommending rejection of the offer, the Conversion Price shall be reduced so
that the same shall equal the price determined by multiplying the Conversion
Price in effect immediately prior to the Offer Expiration Time by a fraction,
(i) the numerator of which shall be (A) the number of shares of Common Stock
outstanding (including any tendered or exchanged shares) on the Offer Expiration
Time multiplied by (B) the Current Market Price of the Common Stock on the
Trading Day next succeeding the Offer Expiration Time and (ii) the denominator
of which shall be the sum of (A) the fair market value (determined as aforesaid)
of the aggregate consideration payable to shareholders based on the acceptance
(up to any maximum specified in the terms of the tender or exchange offer) of
all shares validly tendered or exchanged and not withdrawn as of the Offer
Expiration Time (the shares deemed so accepted, up to any such maximum, being
referred to as the "Accepted Purchased Shares") and (B) the product of (x) the
number of shares of Common Stock outstanding (less any Accepted Purchased
Shares) on the Offer Expiration Time and (y) the Current Market Price of the
Common Stock on the Trading Day next succeeding the Offer Expiration Time, such
reduction to become effective immediately prior to the opening of business on
the day following the Offer Expiration Time. In the event that such Person is
obligated to purchase shares pursuant to any such tender or exchange offer, but
such Person is permanently prevented by applicable law from effecting any such
purchases or all such purchases are rescinded, the Conversion Price shall again
be adjusted to be the Conversion Price which would then be in effect if such
tender or exchange offer had not been made.

     (h) In the event that the Company distributes rights or warrants (other
than those referred to in Section 8(d)) pro rata to holders of Common Stock, so
long as any such rights or warrants have not expired or been redeemed by the
Company, the holder of any Notes surrendered for conversion will be entitled to
receive upon such conversion, in addition to the shares of Common Stock issuable
upon such conversion, a number of rights or warrants determined as follows: (i)
if such conversion occurs on or prior to the date for the distribution to the
holders of rights or warrants of separate certificates evidencing such rights or
warrants (the "Distribution Date"), the same number of rights or warrants to
which a holder of a number of shares of Common Stock equal to the number of
shares of Common Stock issuable upon conversion is entitled at the time of such
conversion in accordance with the terms and provisions of and applicable to the
rights or warrants, and (ii) if such conversion occurs after such Distribution
Date, the same number of rights or warrants to which a holder of the number of
shares of Common Stock into which such Note was convertible immediately prior to
such Distribution Date would have been entitled on such Distribution Date in
accordance with the terms and provisions of and applicable to the rights or
warrants. The Conversion Price of the Note will not be subject to adjustment on
account of any declaration, distribution or exercise of such rights or warrants.

     (i) For purposes of Sections 8 and 9, the following terms shall have the
meaning indicated:

     (1) "Closing Price" with respect to any securities on any day shall mean
the closing sale price, regular way, on such day or, in case no such sale takes
place on such day, the average of the reported closing bid and asked prices,
regular way, in each case as quoted on the Nasdaq National Market or, if such
security is not quoted or listed or admitted to trading on such Nasdaq National
Market, on the principal national security exchange or quotation system on which
such security is quoted or listed or admitted to trading or, if not quoted or
listed or admitted to trading on any national securities exchange or quotation
system, the average of the closing bid and asked prices of such security on the
over-the-counter market on the day in question as reported by the National
Quotation Bureau Incorporated, or a similar generally accepted reporting
service, or if not so available, in such manner as furnished by any New York
Stock Exchange member firm selected from time to time by the Board of Directors
for that purpose, or a price determined in good faith by the Board of Directors
or, to the extent permitted by applicable law, a duly authorized committee
thereof, whose determination shall be conclusive.

     (2) "Current Market Price" per share of Common Stock on any date shall be
deemed to be the average of the daily Closing Prices for the five (5)
consecutive trading days selected by the Company commencing not more than twenty
(20) Trading Days before, and ending not later than, the earlier of the day in
question and the day before the "ex date" with respect to the issuance or
distribution requiring such computation. For purposes of this paragraph, the
term "ex date," when used with respect to any issuance or distribution, shall
mean the first date on which the Common Stock trades regular way in such market
without the right to receive such issuance or distribution.

     (3) "fair market value" shall mean the amount which a willing buyer would
pay a willing seller in an arm's-length transaction.

     (4) "Record Date" shall mean, with respect to any dividend, distribution or
other transaction or event in which the holders of Common Stock have the right
to receive any cash, securities or other property or in which the Common Stock
(or other applicable security) is exchanged for or converted into any
combination of cash, securities or other property, the date fixed for
determination of shareholders entitled to receive such cash, securities or other
property (whether such date is fixed by the Board of Directors or by statute,
contract or otherwise).

     (5) "Trading Day" shall mean (x) if the applicable security is quoted on
the Nasdaq National Market, a day on which trades may be made thereon or (y) if
the applicable security is listed or admitted for trading on the New York Stock
Exchange or another national security exchange, a day on which the New York
Stock Exchange or another national security exchange is open for business or (z)
if the applicable security is not so listed, admitted for trading or quoted, any
day other than a Saturday or Sunday or a day on which banking institutions in
the State of New York are authorized or obligated by law or executive order to
close.

     (j) The Company may make such reductions in the Conversion Price, in
addition to those required by Sections 8.5(a), (b), (c), (d), (e), (f) or (g) as
the Board of Directors considers to be advisable to avoid or diminish any income
tax to holders of Common Stock or rights to purchase Common Stock resulting from
any dividend or distribution of stock (or rights to acquire stock) or from any
event treated as such for income tax purposes.

     To the extent permitted by applicable law, the Company from time to time
may reduce the Conversion Price by any amount for any period of time if the
period is at least twenty (20) days, the reduction is irrevocable during the
period and the Board of Directors shall have made a determination that such
reduction would be in the best interests of the Company, which determination
shall be conclusive. Whenever the Conversion Price is reduced pursuant to the
preceding sentence, the Company shall mail to the Purchaser a notice of the
reduction at least fifteen (15) days prior to the date the reduced Conversion
Price takes effect, and such notice shall state the reduced Conversion Price and
the period during which it will be in effect.

     (k) No adjustment in the Conversion Price shall be required unless such
adjustment would require an increase or decrease of at least one percent (1%) in
such price; provided, however, that any adjustments that by reason of this
Section 8.5(k) are not required to be made shall be carried forward and taken
into account in any subsequent adjustment. All calculations under this Section 8
shall be made by the Company and shall be made to the nearest cent or to the
nearest one-hundredth (1/100) of a share, as the case may be. No adjustment need
be made for rights to purchase Common Stock pursuant to a Company plan for
reinvestment of dividends or interest. To the extent the Note becomes
convertible into cash, assets, property or securities (other than capital stock
of the Company), no adjustment need be made thereafter as to the cash, assets,
property or such securities. Interest will not accrue on the cash.

     (l) Whenever the Conversion Price is adjusted as herein provided, the
Company shall promptly deliver to the Purchaser a certificate signed by an
executive officer of the Company setting forth the Conversion Price after such
adjustment and setting forth a brief statement of the facts requiring such
adjustment. Failure to deliver such notice shall not affect the legality or
validity of any such adjustment.

     (m) In any case in which this Section 8.5 provides that an adjustment shall
become effective immediately after a Record Date for an event, the Company may
defer until the occurrence of such event (i) issuing to the Purchaser if the
Purchaser converted after such record date and before the occurrence of such
event the additional shares of Common Stock issuable upon such conversion by
reason of the adjustment required by such event over and above the Common Stock
issuable upon such conversion before giving effect to such adjustment and (ii)
paying to such holder any amount in cash in lieu of any fraction pursuant to
Section 8.3.

     (n) For purposes of this Section 8.5, the number of shares of Common Stock
at any time outstanding shall not include shares held in the treasury of the
Company but shall include shares issuable in respect of scrip certificates
issued in lieu of fractions of shares of Common Stock. The Company will not pay
any dividend or make any distribution on shares of Common Stock held in the
treasury of the Company.

     8.6 Effect of Reclassification, Consolidation, Merger or Sale

     If any of the following events occur, namely (a) any reclassification or
change of the outstanding shares of Common Stock (other than a subdivision or
combination to which Section 8.5(c) applies), (b) any consolidation, merger or
combination of the Company with another Person as a result of which holders of
Common Stock shall be entitled to receive stock, other securities or other
property or assets (including cash) with respect to or in exchange for such
Common Stock, or (c) any sale or conveyance of all or substantially all of the
properties and assets of the Company to any other Person as a result of which
holders of Common Stock shall be entitled to receive stock, other securities or
other property or assets (including cash) with respect to or in exchange for
such Common Stock, then the Company or the successor or purchasing Person, as
the case may be, shall execute with the Purchaser an amendment to this Agreement
providing that the Note shall be convertible into the kind and amount of shares
of stock, other securities or other property or assets (including cash)
receivable upon such reclassification, change, consolidation, merger,
combination, sale or conveyance by a holder of the number of shares of Common
Stock into which the Note was convertible immediately prior thereto (assuming,
for such purposes, a sufficient number of authorized shares of Common Stock is
available to convert the Note) immediately prior to such reclassification,
change, consolidation, merger, combination, sale or conveyance assuming such
holder of Common Stock did not exercise his rights of election, if any, as to
the kind or amount of securities, cash or other property receivable upon such
reclassification, change, consolidation, merger, combination, sale or conveyance
(provided that, if the kind or amount of stock, other securities or other
property or assets (including cash) receivable upon such reclassification,
change, consolidation, merger, combination, sale or conveyance is not the same
for each share of Common Stock in respect of which such rights of election shall
not have been exercised ("non-electing share"), then for the purposes of this
Section 8.6 the kind and amount of securities, cash or other property receivable
upon such reclassification, change, consolidation, merger, combination, sale or
conveyance for each non-electing share shall be deemed to be the kind and amount
so receivable per share by a plurality of the non-electing shares). Such
amendment shall provide for adjustments which shall be as nearly equivalent as
may be practicable to the adjustments provided for in this Section 8.

     The above provisions of this Section 8.6 shall similarly apply to
successive reclassifications, changes, consolidations, mergers, combinations,
sales and conveyances.

     If this Section 8.6  applies to any event or occurrence,  Section 8.5 shall
not apply.

     8.7 Taxes on Shares Issued

     The issue of stock certificates on conversions of the Note shall be made
without charge to the Purchaser or any holder thereof for any tax in respect of
the issue thereof. The Company shall be required to pay any tax which may be
payable in respect of any transfer involved in the issue and delivery of stock
as a result of the conversion of the Note (or any portion thereof).

     8.8  Reservation  of  Shares;  Shares  to Be Fully  Paid;  Compliance  with
Governmental Requirements; Listing of Common Stock

     The Company shall provide, free from preemptive rights, out of its
authorized but unissued shares or shares held in treasury, sufficient shares of
Common Stock to provide for the conversion of the Note from time to time as the
Note is presented for conversion.

     Before taking any action which would cause an adjustment reducing the
Conversion Price below the then par value, if any, of the shares of Common Stock
issuable upon conversion of the Note, the Company will take all corporate action
which may, in the opinion of its counsel, be necessary in order that the Company
may validly and legally issue shares of such Common Stock at such adjusted
Conversion Price.

     The Company covenants that all shares of Common Stock which may be issued
upon conversion of the Note will upon issue be fully paid and non-assessable by
the Company and free from all taxes, liens and charges with respect to the issue
thereof.

     The Company covenants that, if any shares of Common Stock to be provided
for the purpose of conversion of the Note hereunder require registration with or
approval of any governmental authority under any federal or state law before
such shares may be validly issued upon conversion, the Company will in good
faith and as expeditiously as possible endeavor to secure such registration or
approval, as the case may be.

     The Company further covenants that, if at any time the Common Stock shall
be listed on the Nasdaq National Market or any other national securities
exchange or automated quotation system, the Company will, if permitted by the
rules of such exchange or automated quotation system, list and keep listed, so
long as the Common Stock shall be so listed on such exchange or automated
quotation system, all Common Stock issuable upon conversion of the Note;
provided, however, that, if the rules of such exchange or automated quotation
system permit the Company to defer the listing of such Common Stock until the
first conversion of the Note into Common Stock in accordance with the provisions
of this Agreement, the Company covenants to list such Common Stock issuable upon
conversion of the Note in accordance with the requirements of such exchange or
automated quotation system at such time.

     8.9 Notice to Holders Prior to Certain Actions

     In case:

     (a) the Company shall declare a dividend (or any other distribution) on its
Common Stock that would require an adjustment in the Conversion Price pursuant
to Section 8.5; or

     (b) the Company shall authorize the granting to the holders of all or
substantially all of its Common Stock of rights or warrants to subscribe for or
purchase any share of any class or any other rights or warrants; or

     (c) of any reclassification or reorganization of the Common Stock of the
Company (other than a subdivision or combination of its outstanding Common
Stock, or a change in par value, or from par value to no par value, or from no
par value to par value), or of any consolidation or merger to which the Company
is a party and for which approval of any shareholders of the Company is
required, or of the sale or transfer of all or substantially all of the assets
of the Company or any Significant Subsidiary; or

     (d) of the voluntary or involuntary dissolution, liquidation or winding up
of the Company or any significant subsidiary; then

     the Company shall mail to the Purchaser as promptly as possible but in any
event at least fifteen (15) days prior to the applicable date hereinafter
specified, a notice stating (i) the date on which a record is to be taken for
the purpose of such dividend, distribution or rights or warrants, or, if a
record is not to be taken, the date as of which the holders of Common Stock of
record to be entitled to such dividend, distribution or rights are to be
determined, or (ii) the date on which such reclassification, consolidation,
merger, sale, transfer, dissolution, liquidation or winding up is expected to
become effective or occur, and the date as of which it is expected that holders
of Common Stock of record shall be entitled to exchange their Common Stock for
securities or other property deliverable upon such reclassification,
consolidation, merger, sale, transfer, dissolution, liquidation or winding up.
Failure to give such notice, or any defect therein, shall not affect the
legality or validity of such dividend, distribution, reclassification,
consolidation, merger, sale, transfer, dissolution, liquidation or winding up.

     9. Redemption of Note

     9.1 Redemption by the Company

     Commencing May 20, 2002 until May 20, 2003, the Note may be redeemed by the
Company, in whole or in an amount of at least Fifty Million Dollars
($50,000,000), and in increments of One Million Dollar ($1,000,000) in excess
thereof, upon notice as set forth in Section 9.2, at a redemption price equal to
the face amount of the portion of Note to be redeemed plus accrued and unpaid
interest, if any, to, but excluding, the date of redemption (the "Redemption
Date"), if the Closing Price shall have equaled or exceeded one hundred twenty
percent (120%) of the Conversion Price then in effect for the twenty (20)
consecutive Trading Days ending on the date of mailing of the notice of
redemption pursuant to Section 9.2 (the "Notice Date").

     At any time on or after May 20, 2003, and prior to maturity, the Note may
be redeemed at the option of the Company, in whole or in an amount of at least
Fifty Million Dollars ($50,000,000), and in increments of One Million Dollar
($1,000,000) in excess thereof, upon notice as set forth in Section 9.2, at the
face amount of the portion of the Note to be redeemed, together with accrued and
unpaid interest, if any, to, but excluding, the Redemption Date, if the Closing
Price shall have equaled or exceeded the Conversion Price then in effect for the
twenty (20) consecutive Trading Days ending on the Notice Date. The Note shall
remain convertible until fully redeemed or repaid.

     9.2 Notice of Redemption

     In case the Company shall desire to exercise the right to redeem all or, as
the case may be, any part of the Note pursuant to Section 9.1, it shall fix a
date for redemption and shall mail or cause to be mailed a notice of such
redemption not fewer than forty-five (45) nor more than sixty (60) days prior to
the date fixed for redemption to the Purchaser. The Company may not give notice
of any redemption of the Note if a default in payment of interest on the Note
has occurred and is continuing. Such mailing shall be made in accordance with
Section 13.6.

     Each such notice of redemption shall specify the aggregate principal amount
of the Note to be redeemed, the date fixed for redemption (which shall be a
Business Day), the place or places of payment, that payment will be made upon
presentation and surrender of the Note, that interest accrued to the Redemption
Date will be paid as specified in such notice, and that on and after such date
interest thereon or on the portion thereof to be redeemed will cease to accrue.
Such notice shall also state the current Conversion Price and that the right to
convert the Note or portions thereof into Common Stock will expire on the
Redemption Date. In case the Note is to be redeemed in part only, the notice of
redemption shall state the portion of the principal amount thereof to be
redeemed and shall state that, on and after the date fixed for redemption, upon
surrender of the Note, a new Note or Notes in principal amount equal to the
unredeemed portion thereof will be issued.

     On or prior to the Redemption Date specified in the notice of redemption
given as provided in this Section 9.2, the Company will set aside, segregate and
hold in trust an amount of money in immediately available funds sufficient to
redeem on the Redemption Date the Note (or portions thereof) so called for
redemption (to the extent not surrendered for conversion into Common Stock),
together with accrued interest to, but excluding, the Redemption Date. If the
Note is converted pursuant hereto prior to such redemption, any money so
segregated and held in trust for the redemption of the Note shall be discharged
from such trust.

     9.3 Payment of Portion of Note Called for Redemption

     If notice of redemption has been given as above provided, the Note or
portion of the Note with respect to which such notice has been given shall,
unless converted into Common Stock pursuant to the terms hereof, become due and
payable on the Redemption Date and at the place or places stated in such notice,
together with interest accrued to, but excluding, the Redemption Date, and on
and after such date (unless the Company shall default in the payment of the
Note, together with interest accrued to such date) interest on the Note or
portion of Note so called for redemption shall cease to accrue and such portion
of the Note shall cease after the close of business on the Business Day next
preceding the Redemption Date to be convertible into Common Stock and the
Purchaser shall have no right in respect of such portion of the Note except the
right to receive the principal amount thereof and unpaid interest to, but
excluding, the Redemption Date. On presentation and surrender of the Note at a
place of payment in such notice specified, the Note or the specified portions
thereof shall be paid and redeemed by the Company, together with interest
accrued thereon to, but excluding, the Redemption Date.

     Upon presentation of the Note, if it is to be redeemed in part only, the
Company shall execute authenticate and make available for delivery to the holder
thereof, at the expense of the Company, a new Note or Notes, of authorized
denominations, in principal amount equal to the unredeemed portion of the Note
so presented.

     Notwithstanding the foregoing, the Company shall not redeem any portion of
the Note or mail any notice of redemption during the continuance of a default in
payment of interest on the Note. If any portion of the Note called for
redemption shall not be so paid upon surrender thereof for redemption, the
principal shall, until paid or duly provided for, bear interest from the
Redemption Date at the rate borne by the Note and the Note shall remain
convertible into Common Stock until the principal shall have been paid or duly
provided for.

     10. Events of Default

     10.1 Acceleration

     In case one or more of the following Events of Default (whatever the reason
for such Event of Default and whether it shall be voluntary or involuntary or be
effected by operation of law or pursuant to any judgment, decree or order of any
court or any order, rule or regulation of any administrative or governmental
body) shall have occurred and be continuing:

     (a) default in the payment of any installment of interest upon the Note as
and when the same shall become due and payable, and continuance of such default
for a period of thirty (30) days, whether or not such payment is permitted under
Section 11 hereof; or

     (b) default in the payment of the principal of or premium, if any, on the
Note as and when the same shall become due and payable at maturity, by
acceleration or otherwise, whether or not such payment is permitted under
Section 11 hereof; or

     (c) failure on the part of the Company duly to observe or perform any
covenants or agreements (other than the payment obligations described in clause
(a) and (b) above) on the part of the Company in the Note or in this Agreement
continued for a period of sixty (60) days after the date on which written notice
of such failure, requiring the Company to remedy the same, shall have been given
by the Purchaser to the Company; or

     (d) the Company or any Significant Subsidiary shall commence a voluntary
case or other proceeding seeking liquidation, reorganization or other relief
with respect to itself or any Significant Subsidiary or its or such Significant
Subsidiary's debts under any bankruptcy, insolvency or other similar law now or
hereafter in effect or seeking the appointment of a trustee, receiver,
liquidator, custodian or other similar official of it or any Significant
Subsidiary or any substantial part of the property of the Company or any
Significant Subsidiary, or shall consent to any such relief or to the
appointment of or taking possession by any such official in an involuntary case
or other proceeding commenced against it or any Significant Subsidiary, or shall
make a general assignment for the benefit of creditors, or shall fail generally
to pay its debts as they become due; or

     (e) an involuntary case or other proceeding shall be commenced against the
Company or any Significant Subsidiary seeking liquidation, reorganization or
other relief with respect to it or any Significant Subsidiary or its or such
Significant Subsidiary's debts under any bankruptcy, insolvency or other similar
law now or hereafter in effect or seeking the appointment of a trustee,
receiver, liquidator, custodian or other similar official of it or any
Significant Subsidiary or any substantial part of the property of the Company or
any Significant Subsidiary, and such involuntary case or other proceeding shall
remain undismissed and unstayed for a period of ninety (90) consecutive days; or

     (f) final unsatisfied judgements not covered by insurance aggregating in
excess of Five Million Dollars ($5,000,000) at any one time rendered against the
Company or any of its Significant Subsidiaries and not stayed or discharged
within sixty (60) days; or

     (g) the failure of the Company to perform any conversion of the Note
required under this Agreement and the continuance of such failure for thirty
(30) days; or

     (h) default under any mortgage, indenture or instrument under which there
may be issued or by which there may be secured or evidenced any Indebtedness for
money borrowed by the Company or any of its subsidiaries (or the payment of
which is guaranteed by the Company or any of its subsidiaries), other than
indebtedness owed to the Company or a wholly owned subsidiary, whether such
Indebtedness or guarantee now exists, or is created after the date of this
Agreement, which default (i) is caused by a failure to pay principal of or
premium, if any, on such indebtedness or (ii) results in the acceleration of
such indebtedness prior to maturity, and, in each case, the principal amount of
any such indebtedness, together with the principal amount of any other such
indebtedness under which there has been a payment default or the maturity of
which has been so accelerated, aggregates Five Million Dollars ($5,000,000) or
more; or

     (i) the representations and warranties of the Company in this Agreement
were not true and correct in any material respect when made and at the time of
the Closing;

     then, and in each and every such case (other than an Event of Default
specified in Section 10.1(d) or (e) with respect to the Company), unless the
principal of the Note shall have already become due and payable, the Purchaser,
by notice in writing to the Company, may declare the principal of and premium,
if any, on the Note and the interest accrued thereon to be due and payable
immediately, and upon any such declaration the same shall become and shall be
immediately due and payable, anything in this Agreement or in the Note contained
to the contrary notwithstanding. If an Event of Default specified in Section
10.1(d) or (e) with respect to the Company occurs, the principal of the Note and
the interest accrued thereon shall be immediately and automatically due and
payable without necessity of further action. This provision, however, is subject
to the conditions that if, at any time after the principal of the Note shall
have been so declared due and payable, and before any judgment or decree for the
payment of the monies due shall have been obtained or entered as hereinafter
provided, the Company shall pay a sum sufficient to pay all matured installments
of interest upon the Note and the principal of and premium, if any, on the Note
which shall have become due otherwise than solely by a declaration of
acceleration (with interest on overdue installments of interest (to the extent
that payment of such interest is enforceable under applicable law) and on such
principal and premium, if any, at the rate borne by the Note, to the date of
such payment or deposit), and if any and all defaults under this Agreement,
other than the nonpayment of principal of and premium, if any, and accrued
interest on the Note which shall have become due solely by declaration of
acceleration, shall have been cured or waived, then and in every such case the
Purchaser, by written notice to the Company, may waive all defaults or Events of
Default and rescind and annul such declaration and its consequences; but no such
waiver or rescission and annulment shall extend to or shall affect any
subsequent default or Event of Default, or shall impair any right consequent
thereon.

     10.2 Payments of Note on Default; Suit Therefor

     The Company covenants that (a) in case default shall be made in the payment
of any installment of interest upon the Note as and when the same shall become
due and payable, and such default shall have continued for a period of thirty
(30) days, or (b) in case default shall be made in the payment of the principal
of or premium, if any, on the Note as and when the same shall have become due
and payable, whether at maturity of the Note or in connection with any
redemption by the Company under this Agreement or by declaration of acceleration
or otherwise, then, upon the Purchaser's demand, the Company will pay to the
Purchaser the whole amount that then shall have become due and payable on the
Note for principal and premium, if any, or interest, as the case may be, with
interest upon the overdue principal and premium, if any, and (to the extent that
payment of such interest is enforceable under applicable law) upon the overdue
installments of interest at a floating LIBOR Rate adjusted quarterly on each
March 31, June 30, September 30 and December 31 during the period that such
default is continuing; and, in addition thereto, such further amount as shall be
sufficient to cover the costs and expenses of collection.

     In case there shall be pending proceedings for the bankruptcy or for the
reorganization of the Company or any other obligor on the Note under Title 11 of
the United States Code, or any other applicable law, or in case a receiver,
assignee or trustee in bankruptcy or reorganization, liquidator, sequestrator or
similar official shall have been appointed for or taken possession of the
Company or such other obligor, the property of the Company or such other
obligor, or in the case of any other judicial proceedings relative to the
Company or such other obligor upon the Note, or to the creditors or property of
the Company or such other obligor, then irrespective of whether the principal of
the Note shall then be due and payable as therein expressed or by declaration or
otherwise and irrespective of whether the Purchaser shall have made any demand
pursuant to the provisions of this Section 10.2, the Purchaser shall be entitled
and empowered, by intervention in such proceedings or otherwise, to file and
prove a claim or claims for the whole amount of principal, premium, if any, and
interest owing and unpaid in respect of the Note, and, in case of any judicial
proceedings, to file such proofs of claim and other papers or documents as may
be necessary or advisable in order to have the Purchaser's claims allowed in
such judicial proceedings relative to the Company or any other obligor on the
Note, its or their creditors, or its or their property, and to collect and
receive any monies or other property payable or deliverable on any such claims.
To the extent that such payment of reasonable compensation, expenses, advances
and disbursements out of the estate in any such proceedings shall be denied for
any reason, payment of the same shall be secured by a lien on, and shall be paid
out of, any and all distributions, dividends, monies, securities and other
property which the Purchaser may be entitled to receive in such proceedings,
whether in liquidation or under any plan of reorganization or arrangement or
otherwise.

     11. Subordination Of Note

     11.1 Agreement of Subordination

     The Company covenants and agrees, and the Purchaser covenants and agrees,
that the Note shall be issued subject to the provisions of this Section 11 and
the Purchaser accepts and agrees to be bound by such provisions.

     The payment of the principal of, premium, if any, and interest on the Note
issued hereunder shall, to the extent and in the manner hereinafter set forth,
be subordinated and subject in right of payment to the prior payment in full in
cash or other payment satisfactory to the holders of Senior Indebtedness of all
Senior Indebtedness of the Company, whether outstanding at the date of this
Agreement or thereafter incurred.

     No provision of this Section 10 shall prevent the occurrence of any default
or Event of Default hereunder.

     11.2 Payments on the Note

     No payment shall be made with respect to the principal of, premium, if any,
or interest on the Note if:

     (a) a default in the payment of principal, premium, if any, or interest in
respect of Designated Senior Indebtedness occurs and is continuing (a "Payment
Default"), unless and until such Payment Default shall have been cured or waived
or shall have ceased to exist; or

     (b) a default, other than a Payment Default, on any Designated Senior
Indebtedness occurs and is continuing that then permit holders of such
Designated Senior Indebtedness to accelerate its maturity and the Purchaser
receives a notice of the default (a "Payment Blockage Notice") from a
Representative of Designated Senior Indebtedness (a "Non-Payment Default").

     If the Purchaser receives any Payment Blockage Notice pursuant to clause
(b) above, no subsequent Payment Blockage Notice shall be effective for purposes
of this Section 11.2 unless and until (i) at least three hundred sixty-five
(365) days shall have elapsed since the initial effectiveness of the immediately
prior Payment Blockage Notice and (ii) all scheduled payments of principal,
premium, if any, and interest on the Note that have come due have been paid in
full in cash. No Non-Payment Default that existed or was continuing on the date
of delivery of any Payment Blockage Notice to the Purchaser shall be, or be
made, the basis for a subsequent Payment Blockage Notice.

     The Company may and shall resume payments on and distributions in respect
of the Note upon:

     (1) in the case of a Payment Default, the earlier of (i) the date upon
which any such Payment Default is cured or waived or ceases to exist or the
underlying indebtedness has been repaid or (ii) two hundred seventy (270) days
after such Payment Default, or

     (2) in the case of a Non-Payment Default, the earlier of (i) the date upon
which such default is cured or waived or ceases to exist or (ii) one hundred
seventy-nine (179) days after the applicable Payment Blockage Notice is received
by the Purchaser if the maturity of such Designated Senior Indebtedness has not
been accelerated and no Payment Default with respect to any Designated Senior
Indebtedness has occurred which has not been cured or waived (in which case
clause (1) shall be applicable) or (iii) the Person who declared such Payment
Blockage approves such payment,

     unless this Section 11 otherwise prohibits the payment or distribution at
the time of such payment or distribution.

     Upon any payment by the Company, or distribution of assets of the Company
of any kind or character, whether in cash, property or securities, to creditors
upon any dissolution or winding up or liquidation or reorganization of the
Company, whether voluntary or involuntary or in bankruptcy, insolvency,
receivership or other proceedings, all amounts due or to become due upon all
Senior Indebtedness shall first be paid in full in cash or other payment
satisfactory to the holders of such Senior Indebtedness, or payment thereof in
accordance with its terms provided for in cash or other payment satisfactory to
the holders of such Senior Indebtedness before any payment is made on account of
the principal of, premium, if any, or interest on the Note, and upon any such
dissolution or winding up or liquidation or reorganization of the Company or
bankruptcy, insolvency, receivership or other proceeding, any payment by the
Company, or distribution of assets of the Company of any kind or character,
whether in cash, property or securities, to which the Purchaser would be
entitled, except for the provisions of this Section 11, shall (except as
aforesaid) be paid by the Company or by any receiver, trustee in bankruptcy,
liquidating trustee, agent or other Person making such payment or distribution,
or by the Purchaser if received by them or it, directly to the holders of Senior
Indebtedness (pro rata to such holders on the basis of the respective amounts of
Senior Indebtedness held by such holders, or as otherwise required by law or a
court order) or their Representative or Representatives, or to the trustee or
trustees under any indenture pursuant to which any instruments evidencing any
Senior Indebtedness may have been issued, as their respective interests may
appear, to the extent necessary to pay all Senior Indebtedness in full in cash
or other payment satisfactory to the holders of such Senior Indebtedness, after
giving effect to any concurrent payment or distribution to or for the holders of
Senior Indebtedness, before any payment or distribution is made to the
Purchaser.

     For purposes of this Section 11, the words, "cash, property or securities"
shall not be deemed to include shares of stock of the Company as reorganized or
readjusted, or securities of the Company or any other corporation provided for
by a plan of reorganization or readjustment, the payment of which is
subordinated at least to the extent provided in this Section 11 with respect to
the Note to the payment of all Senior Indebtedness which may at the time be
outstanding.

     In the event of the acceleration of the Note because of an Event of
Default, no payment or distribution shall be made to the Purchaser in respect of
the principal of, premium, if any, or interest on the Note, until all Senior
Indebtedness has been paid in full in cash or other payment satisfactory to the
holders of Senior Indebtedness or such acceleration is rescinded in accordance
with the terms of this Agreement. If payment of the Note is accelerated because
of an Event of Default, the Company shall promptly notify holders of Designated
Senior Indebtedness of the acceleration.

     In the event that, notwithstanding the foregoing provisions, any payment or
distribution of assets of the Company of any kind or character, whether in cash,
property or securities (including, without limitation, by way of setoff or
otherwise), prohibited by the foregoing provisions in this Section 11.2, shall
be received by the Purchaser before all Senior Indebtedness is paid in full in
cash or other payment satisfactory to the holders of such Senior Indebtedness,
or provision is made for such payment thereof in accordance with its terms in
cash or other payment satisfactory to the holders of such Senior Indebtedness,
such payment or distribution shall be held in trust for the benefit of and shall
be paid over or delivered to the holders of Senior Indebtedness or their
Representative or Representatives, or to the trustee or trustees under any
indenture pursuant to which any instruments evidencing any Senior Indebtedness
may have been issued, as their respective interests may appear, as calculated by
the Company, for application to the payment of any Senior Indebtedness remaining
unpaid to the extent necessary to pay all Senior Indebtedness in full in cash or
other payment satisfactory to the holders of such Senior Indebtedness, after
giving effect to any concurrent payment or distribution to or for the holders of
such Senior Indebtedness.

     11.3 Subrogation of Note

     Subject to the payment in full of all Senior Indebtedness, the rights of
the holder of the Note shall be subrogated to the extent of the payments or
distributions made to the holders of such Senior Indebtedness pursuant to the
provisions of this Section 11 (equally and ratably with the holders of all
indebtedness of the Company that by its express terms, is subordinated to other
indebtedness of the Company to substantially the same extent as the Note is
subordinated and is entitled to like rights of subrogation) to the rights of the
holders of Senior Indebtedness to receive payments or distributions of cash,
property or securities of the Company applicable to the Senior Indebtedness
until the principal, premium, if any, and interest on the Note shall be paid in
full; and, for the purposes of such subrogation, no payments or distributions to
the holders of the Senior Indebtedness of any cash, property or securities to
which the Purchaser would be entitled except for the provisions of this Section
11, and no payment over pursuant to the provisions of this Section 11, to or for
the benefit of the holders of Senior Indebtedness by the Purchaser, shall, as
among the Company, its creditors other than holders of Senior Indebtedness, and
the Purchaser be deemed to be a payment by the Company to or on account of the
Senior Indebtedness; and no payments or distributions of cash, property or
securities to or for the benefit of the Purchaser pursuant to the subrogation
provisions of this Section 11, which would otherwise have been paid to the
holders of Senior Indebtedness, shall be deemed to be a payment by the Company
to or for the account of the Note. It is understood that the provisions of this
Section 11 are and are intended solely for the purposes of defining the relative
rights of the Purchaser, on the one hand, and the holders of the Senior
Indebtedness, on the other hand.

     Nothing contained in this Section 11 or elsewhere in this Agreement or in
the Note is intended to or shall impair, as among the Company, its creditors
other than the holders of Senior Indebtedness, and the Purchaser, the obligation
of the Company, which is absolute and unconditional, to pay to the Purchaser the
principal of, premium, if any, and interest on the Note as and when the same
shall become due and payable in accordance with their terms, or is intended to
or shall affect the relative rights of the Purchaser and creditors of the
Company other than the holders of the Senior Indebtedness, nor shall anything
herein or therein prevent the Purchaser from exercising all remedies otherwise
permitted by applicable law upon default under this Agreement, subject to the
rights, if any, under this Section 11 of the holders of Senior Indebtedness in
respect of cash, property or securities of the Company received upon the
exercise of any such remedy.

     11.4 Authorization to Effect Subordination

     The Purchaser, by its acceptance thereof, authorizes and directs the
Company on the Purchaser's behalf to take such action as may be necessary or
appropriate to effectuate the subordination as provided in this Section 11 and
appoints the Company to act as the Purchaser's attorney-in-fact for any and all
such purposes. If the Company does not file a proper proof of claim or proof of
debt in the form required in any bankruptcy, dissolution, winding up,
liquidation or reorganization proceeding at least thirty (30) days before the
expiration of the time to file such claim, the holders of any Senior
Indebtedness or their representatives are hereby authorized to file an
appropriate claim for and on behalf of the Purchaser.

     11.5 No Impairment of Subordination

     No right of any present or future holder of any Senior Indebtedness to
enforce subordination as herein provided shall at any time in any way be
prejudiced or impaired by any act or failure to act on the part of the Company
or by any act or failure to act, in good faith, by any such holder, or by any
noncompliance by the Company with the terms, provisions and covenants of this
Agreement, regardless of any knowledge thereof which any such holder may have or
otherwise be charged with.

     11.6 Certain Conversions Not Deemed Payment

     For the purposes of this Section 11 only, (a) the issuance and delivery of
junior securities upon conversion of the Note in accordance with Section 8 shall
not be deemed to constitute a payment or distribution on account of the
principal of, premium, if any, or interest on the Note or on account of the
purchase or other acquisition of the Note, and (b) the payment, issuance or
delivery of cash (except in satisfaction of fractional shares pursuant to
Section 8.3), property or securities (other than junior securities) upon
conversion of a Note shall be deemed to constitute payment on account of the
principal of, premium, if any, or interest on such Note. For the purposes of
this Section 11.6, the term "junior securities" means (a) shares of any stock of
any class of the Company or (b) securities of the Company that are subordinated
in right of payment to all Senior Indebtedness that may be outstanding at the
time of issuance or delivery of such securities to substantially the same extent
as, or to a greater extent than, the Note is so subordinated as provided in this
Section. Nothing contained in this Section 11 or elsewhere in this Agreement or
in the Note is intended to or shall impair, as among the Company, its creditors
(other than holders of Senior Indebtedness) and the Purchaser, the right, which
is absolute and unconditional, of the Purchaser to convert the Note in
accordance with Section 8.

     11.7 Senior Indebtedness Entitled to Rely

     The holders of Senior Indebtedness (including, without limitation,
Designated Senior Indebtedness) shall have the right to rely upon this Section
11, and no amendment or modification of the provisions contained herein shall
diminish the rights of such holders unless representatives of such holders shall
have agreed in writing thereto.

     11.8 Reliance on Judicial Order or Certificate of Liquidating Agent

     Upon any payment or distribution of assets of the Company referred to in
this Section 11, the Purchaser shall be entitled to rely upon any order or
decree entered by any court of competent jurisdiction in which such insolvency,
bankruptcy, receivership, liquidation, reorganization, distribution, winding up
or similar case or proceeding is pending, or a certificate of the trustee in
bankruptcy, liquidating trustee, custodian, receiver, assignee for the benefit
of creditors, agent or other Person making such payment or dissolution,
delivered to the Purchaser, for the purpose of ascertaining the Persons entitled
to participate in such payment or distribution, the holders of Senior
Indebtedness and other indebtedness of the Company, the amount thereof or
payable thereon, the amount or amounts paid or distributed thereon and all other
facts pertinent thereto or to this Section 11. 11.9 Distribution or Notice to
Representative

     Whenever  a  distribution  is to be made or a notice  given to a holder  of
Senior Indebtedness of the Company,  the distribution may be made and the notice
given to its  representative  (if any).  11.10  Purchaser  Not a  Fiduciary  for
Holders of Senior Indebtedness

     The Purchaser shall not be deemed to owe any fiduciary duty to the holders
of Senior Indebtedness of the Company and shall not be liable to any such
holders if it shall mistakenly pay over or distribute to the Company or any
other person, money or assets to which holders of Senior Indebtedness of the
Company shall be entitled by virtue of this Section 11 or otherwise.

     12. Transfer

     12.1 Restrictions on Transfer

     (a) Unless (i) the Company consents in writing prior to such transfer, (ii)
such transfer is to a Person that is an Affiliate of the Purchaser or (iii) such
transfer is made in accordance with the terms of this Section 12, the Purchaser
shall not transfer the Note to any Person.

     (b) Notwithstanding anything to the contrary contained herein, the
Purchaser may only transfer the Note in accordance with this Section 12 if the
aggregate principal amount of the portion of the Note to be so transferred is
greater than Fifty Million Dollars ($50,000,000).

     12.2 First Refusal Rights

     (a) At least six (6) Business Days prior to the effective date of any
proposed transfer of any portion of the Note (a "Transfer"), the Purchaser or
the then holder of such portion of the Note (each, a "Transferring Holder")
shall deliver a written notice (the "Offer Notice") to the Company specifying in
reasonable detail the identity of the prospective transferee(s), the aggregate
principal amount of the portion of the Note to be transferred (the "Subject
Securities") and the price (if any) and other terms and conditions of the
proposed Transfer. The Transferring Holder shall not consummate such proposed
Transfer until at least six (6) Business Days after the delivery of the Offer
Notice, unless the parties to the Transfer have been finally determined pursuant
to this Section 12 prior to the expiration of such 6-Business Day period (the
date of the first to occur of such delivery or such final determination is
referred to herein as the "Authorization Date").

     (b) The Company may elect to redeem all (but not less than all) of the
Subject Securities, at a redemption price equal to the price specified in the
Offer Notice by delivering written notice of such election to the Transferring
Holder as soon as practicable, but in any event within five (5) Business Days
after delivery of the Offer Notice.

     (c) If the Company has elected to redeem all of the Subject Securities from
the Transferring Holder, such redemption shall be consummated (i) as soon as
practicable after delivery of the election notice(s) to the Transferring Holder,
but in any event within twenty (20) days after the Authorization Date, and (ii)
in accordance with the terms of Section 9.3.

     (d) If the Company does not elect to redeem all of the Subject Securities,
the Transferring Holder may, within the forty-five (45) days following the
Authorization Date, transfer such Subject Securities to the transferee(s)
specified in the Offer Notice on terms no more favorable to the transferee(s)
thereof than specified in the Offer Notice. Any Subject Securities not so
transferred within such 45-day period shall again be subject to the provisions
of this Section 12 upon any subsequent Transfer.

     12.3 Transfer Procedures

     (a) The Company shall cause to be kept at its offices a register (the
register maintained in such office and in any other office or agency of the
Company designated pursuant to Section 6.2 being herein sometimes collectively
referred to as the "Note register") in which, subject to such reasonable
regulations as it may prescribe, the Company shall provide for the registration
of the Note and of Transfers of the Note. The Note register shall be in written
form or in any form capable of being converted into written form within a
reasonably prompt period of time. The Company is hereby appointed "Note
registrar" for the purpose of registering the Note and Transfers of the Note as
herein provided. The Company may appoint one or more co-registrars in accordance
with Section 6.2.

     (b) Upon surrender for registration of transfer of any Note to the Note
registrar or any co-registrar, and satisfaction of the requirements for such
transfer set forth in this Section 12 the Company shall execute and deliver in
the name of the designated transferee or transferees, one or more new Notes of
any authorized denominations and of a like aggregate principal amount and
bearing such restrictive legends as may be required by this Agreement.

     (c) Notes may be exchanged for other Notes of any authorized denominations
and of a like aggregate principal amount, upon surrender of the Notes to be
exchanged at any such office or agency maintained by the Company pursuant to
Section 6.2. Whenever any Notes are so surrendered for exchange, the Company
shall execute, and deliver, the Notes which the holder making the exchange is
entitled to receive bearing registration numbers not contemporaneously
outstanding.

     (d) All Notes issued upon any registration of Transfer or exchange of Notes
shall be the valid obligations of the Company, evidencing the same debt, and
entitled to the same benefits under this Agreement, as the Notes surrendered
upon such registration of Transfer or exchange.

     (e) All Notes presented or surrendered for registration of Transfer or for
exchange, redemption or conversion shall (if so required by the Company or the
Note registrar) be duly endorsed, or be accompanied by a written instrument or
instruments of transfer in form satisfactory to the Company or the Note
registrar, and the Notes shall be duly executed by the Purchaser or holder
thereof or its attorney duly authorized in writing.

     (f) No service charge shall be made for any registration of Transfer or
exchange of Notes, but the Company may require payment of a sum sufficient to
cover any tax, assessment or other governmental charge that may be imposed in
connection with any registration of transfer or exchange of Notes.

     (g) Neither the Company nor any Note registrar shall be required to
exchange or register a Transfer of any Notes or portions thereof surrendered for
conversion pursuant to Section 8.

     (h) Every Note that bears or is required under this Section 12 to bear the
legend set forth in this Section 12.3(h) (together with any Common Stock issued
upon conversion of the Note and required to bear the legend set forth in Section
12.3(h), collectively, the "Restricted Securities") shall be subject to the
restrictions on transfer set forth in this Section 12 (including those set forth
in the legend set forth below) unless such restrictions on transfer shall be
waived by written consent of the Company, and the holder of each such Note, by
such holder's acceptance thereof, agrees to be bound by all such restrictions on
transfer. As used in Sections 12.3(h) and 12.3(i), the term "transfer"
encompasses any sale, pledge, transfer or other disposition whatsoever of any
Restricted Security.

     Any certificate evidencing such Note (and all securities issued in exchange
therefor or substitution thereof, other than Common Stock, if any, issued upon
conversion thereof, which shall bear the legend set forth in Section 12.3(i), if
applicable) shall bear a legend in substantially the following form unless
otherwise agreed by the Company in writing:

     THE NOTE EVIDENCED HEREBY HAS NOT BEEN REGISTERED UNDER THE U.S. SECURITIES
ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR ANY STATE SECURITIES LAWS,
AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD WITHIN THE UNITED STATES OR TO, OR
FOR THE ACCOUNT OR BENEFIT OF, U.S. PERSONS EXCEPT AS SET FORTH IN THE FOLLOWING
SENTENCE. BY ITS ACQUISITION HEREOF, THE HOLDER (1) REPRESENTS THAT (A) IT IS A
"QUALIFIED INSTITUTIONAL BUYER" (AS DEFINED IN RULE 144A UNDER THE SECURITIES
ACT) OR (B) IT IS AN INSTITUTIONAL "ACCREDITED INVESTOR" (AS DEFINED IN RULE
501(A)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT) ("INSTITUTIONAL ACCREDITED
INVESTOR"); (2) AGREES THAT IT WILL NOT, PRIOR TO EXPIRATION OF THE HOLDING
PERIOD APPLICABLE TO SALES OF THE NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE
SECURITIES ACT (OR ANY SUCCESSOR PROVISION), RESELL OR OTHERWISE TRANSFER THE
NOTE EVIDENCED HEREBY OR THE COMMON STOCK ISSUABLE UPON CONVERSION OF SUCH NOTE
EXCEPT (A) TO IMMUNEX CORPORATION OR ANY SUBSIDIARY THEREOF, (B) TO A QUALIFIED
INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, (C)
TO AN INSTITUTIONAL ACCREDITED INVESTOR IN A DENOMINATION OF NO LESS THAN
$250,000 THAT, PRIOR TO SUCH TRANSFER, FURNISHES TO THE COMPANY A SIGNED LETTER
CONTAINING CERTAIN REPRESENTATIONS AND AGREEMENTS RELATING TO THE RESTRICTIONS
ON TRANSFER OF THE NOTE EVIDENCED HEREBY (THE FORM OF WHICH LETTER IS ATTACHED
AS ANNEX A), (D) PURSUANT TO THE EXEMPTION FROM REGISTRATION PROVIDED BY RULE
144 UNDER THE SECURITIES ACT (IF AVAILABLE) OR (E) PURSUANT TO A REGISTRATION
STATEMENT WHICH HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT (AND WHICH
CONTINUES TO BE EFFECTIVE AT THE TIME OF SUCH TRANSFER); (3) AGREES THAT PRIOR
TO SUCH TRANSFER (OTHER THAN A TRANSFER PURSUANT TO CLAUSE (2)(E) ABOVE), IT
WILL FURNISH TO THE COMPANY SUCH CERTIFICATIONS, LEGAL OPINIONS OR OTHER
INFORMATION AS IT MAY REASONABLY REQUIRE TO CONFIRM THAT SUCH TRANSFER IS BEING
MADE PURSUANT TO AN EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE
REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. IN CONNECTION WITH ANY TRANSFER
OF THE NOTE EVIDENCED HEREBY PRIOR TO THE EXPIRATION OF THE HOLDING PERIOD
APPLICABLE TO SALES OF THE NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE
SECURITIES ACT (OR ANY SUCCESSOR PROVISION), THE HOLDER MUST CHECK THE
APPROPRIATE BOX SET FORTH ON THE REVERSE HEREOF RELATING TO THE MANNER OF SUCH
TRANSFER AND SUBMIT THIS CERTIFICATE TO THE COMPANY. IF THE PROPOSED TRANSFEREE
IS AN INSTITUTIONAL ACCREDITED INVESTOR OR IS A PURCHASER WHO IS NOT A U.S.
PERSON, THE HOLDER MUST, PRIOR TO SUCH TRANSFER, FURNISH TO THE COMPANY SUCH
CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS IT MAY REASONABLY REQUIRE
TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT TO AN EXEMPTION FROM, OR IN
A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES
ACT. THIS LEGEND WILL BE REMOVED UPON THE EARLIER OF THE TRANSFER OF THE NOTE
EVIDENCED HEREBY PURSUANT TO CLAUSE (2)(E) ABOVE OR UPON ANY TRANSFER OF THE
NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE SECURITIES ACT (OR ANY SUCCESSOR
PROVISION). AS USED HEREIN, THE TERMS "UNITED STATES" AND "UNITED STATES PERSON"
HAVE THE MEANINGS GIVEN TO THEM BY REGULATION S UNDER THE SECURITIES ACT.

     Any Note (or security issued in exchange or substitution therefor) as to
which such restrictions on transfer shall have expired in accordance with their
terms or as to conditions for removal of the foregoing legend set forth therein
have been satisfied may, upon surrender of such Note for exchange to the Note
registrar in accordance with the provisions of this Section 12, be exchanged for
a new Note or Notes, of like tenor and aggregate principal amount, which shall
not bear the restrictive legend required by this Section 12.3(h).

     (i) Any stock certificate representing Common Stock issued upon conversion
of any Note shall bear a legend in substantially the following form, unless such
Common Stock has been sold pursuant to a registration statement that has been
declared effective under the Securities Act (and which continues to be effective
at the time of such transfer) or such Common Stock has been issued upon
conversion of the Note that have been transferred pursuant to a registration
statement that has been declared effective under the Securities Act, or unless
otherwise agreed by the Company in writing with written notice thereof to the
transfer agent:

     THE COMMON STOCK EVIDENCED HEREBY HAS NOT BEEN REGISTERED UNDER THE UNITED
STATES SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR ANY STATE
SECURITIES LAWS, AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD WITHIN THE UNITED
STATES OR TO, OR FOR THE ACCOUNT OR BENEFIT OF, U.S. PERSONS EXCEPT AS SET FORTH
IN THE FOLLOWING SENTENCE. THE HOLDER HEREOF AGREES THAT, UNTIL THE EXPIRATION
OF THE HOLDING PERIOD APPLICABLE TO SALES OF THE SECURITY EVIDENCED HEREBY UNDER
RULE 144 UNDER THE SECURITIES ACT (OR ANY SUCCESSOR PROVISION), (1) IT WILL NOT
RESELL OR OTHERWISE TRANSFER THE COMMON STOCK EVIDENCED HEREBY EXCEPT (A) TO
IMMUNEX CORPORATION OR ANY SUBSIDIARY THEREOF, (B) TO A "QUALIFIED INSTITUTIONAL
BUYER" (AS DEFINED IN RULE 144A UNDER THE SECURITIES ACT) IN COMPLIANCE WITH
RULE 144A, (C) TO AN INSTITUTIONAL "ACCREDITED INVESTOR" (AS DEFINED IN RULE
501(A)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT) IN A DENOMINATION OF NO
LESS THAN $250,000 THAT PRIOR TO SUCH TRANSFER, FURNISHES TO CHASEMELLON
SHAREHOLDER SERVICES, LLC, AS TRANSFER AGENT (OR A SUCCESSOR TRANSFER AGENT, AS
APPLICABLE), A SIGNED LETTER CONTAINING CERTAIN REPRESENTATIONS AND AGREEMENTS
RELATING TO THE RESTRICTIONS ON TRANSFER OF THE COMMON STOCK EVIDENCED HEREBY
(THE FORM OF WHICH LETTER IS ATTACHED AS ANNEX A), (D) PURSUANT TO THE EXEMPTION
FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT (IF AVAILABLE),
OR (E) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BEEN DECLARED EFFECTIVE
UNDER THE SECURITIES ACT (AND WHICH CONTINUES TO BE EFFECTIVE AT THE TIME OF
SUCH TRANSFER); (2) PRIOR TO SUCH TRANSFER (OTHER THAN A TRANSFER PURSUANT TO
CLAUSE (1)(E) ABOVE), IT WILL FURNISH TO CHASEMELLON SHAREHOLDER SERVICES, LLC,
AS TRANSFER AGENT (OR A SUCCESSOR TRANSFER AGENT, AS APPLICABLE), SUCH
CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS SUCH TRANSFER AGENT MAY
REASONABLY REQUIRE TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT TO AN
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT. THIS LEGEND WILL BE REMOVED UPON THE EARLIER
OF THE TRANSFER OF THE COMMON STOCK EVIDENCED HEREBY PURSUANT TO CLAUSE (1)(E)
ABOVE OR UPON ANY TRANSFER OF THE COMMON STOCK EVIDENCED HEREBY AFTER THE
EXPIRATION OF THE HOLDING PERIOD APPLICABLE TO SALES OF THE SECURITY EVIDENCED
HEREBY UNDER RULE 144 UNDER THE SECURITIES ACT (OR ANY SUCCESSOR PROVISION). AS
USED HEREIN, THE TERMS "UNITED STATES" AND "UNITED STATES PERSON" HAVE THE
MEANINGS GIVEN TO THEM BY REGULATION S UNDER THE SECURITIES ACT.

     Any such Common Stock as to which such restrictions on transfer shall have
expired in accordance with their terms or as to which the conditions for removal
of the foregoing legend set forth therein have been satisfied may, upon
surrender of the certificates representing such shares of Common Stock for
exchange in accordance with the procedures of the transfer agent for the Common
Stock, be exchanged for a new certificate or certificates for a like number of
shares of Common Stock, which shall not bear the restrictive legend required by
this Section 12.3(i).

     13. Miscellaneous

     13.1 Note Payments

     The Company agrees that, so long as the Purchaser shall hold the Note, it
will make payments of principal thereof and premium, if any, and interest
thereon, which comply with the terms of this Agreement, by wire or electronic
funds transfer of immediately available funds for credit to the Purchaser's
account number 123-000-123 at Chase Manhattan Bank, ABA#021-000-021, or such
other account or accounts in the United States as the Purchaser may designate in
writing, notwithstanding any contrary provision herein or in any Note with
respect to the place of payment. In the event that the Purchaser is not the sole
holder of this Note, the Company will pay to the registered holder(s), as set
forth in the Note register at the office or agency of the Company on a pro rata
basis. If the Company receives wiring instructions five (5) Business Days prior
to the Interest Payment Date, the Company shall by wire or electronic funds
transfer of immediately available funds make payment of principal, premium and
interest.

     13.2 Expenses

     The Company will pay all costs and expenses incurred by the Purchaser in
connection with any amendments, waivers or consents under or in respect of this
Agreement or the Note requested by the Company (whether or not such amendment,
waiver or consent becomes effective), including, without limitation: (a) the
costs and expenses incurred in enforcing or defending (or determining whether or
how to enforce or defend) any rights under this Agreement or the Note, and (b)
the costs and expenses, including financial advisors' fees, incurred in
connection with the insolvency or bankruptcy of the Company or in connection
with any workout or restructuring of the transactions contemplated hereby and by
the Note.

     13.3 Consent to Amendments

     This Agreement may be amended, and the Company may take any action herein
prohibited, or omit to perform any act herein required to be performed by it, if
the Company shall obtain the written consent to such amendment, action or
omission to act, of the Purchaser. Notwithstanding anything to the contrary
contained herein, the Company and Purchaser shall cooperate to amend this
Agreement at the Purchaser's request to permit multiple holders of portions of
the Note, and the Purchaser shall cause all prospective transferees to be bound
by the provisions of this Agreement, as amended. All permitted transferees of
the Note will receive all rights, and be subject to all obligations, of
Purchaser hereunder upon execution and delivery of such amended Agreement.

     13.4 Survival of Representations and Warranties; Entire Agreement

     All representations and warranties contained herein or made in writing by
or on behalf of the Company in connection herewith shall survive the execution
and delivery of this Agreement and the Note, the transfer by the Purchaser of
any Note or portion thereof or interest therein and the payment of any Note, and
may be relied upon by any Transferee, regardless of any investigation made at
any time by or on behalf of the Purchaser or any Transferee. All
representations, warranties and covenants contained herein made by the Purchaser
or any holder shall survive the execution and delivery of this Agreement and the
Note, and may be relied upon by the Company and its successors and assigns.
Subject to the preceding sentences, this Agreement and the Note embody the
entire agreement and understanding between the Purchaser and the Company, and
supersede all prior agreements and understandings, relating to the subject
matter hereof.

     13.5 Successors and Assigns

     All covenants and other agreements in this Agreement contained by or on
behalf of any of the parties hereto shall bind and inure to the benefit of the
respective successors and assigns of the parties hereto whether so expressed or
not.

     13.6 Notices

     All written communications provided for hereunder shall be sent by
facsimile transmission and promptly confirmed by nationwide overnight delivery
service (with charges prepaid) and (x) if to the Purchaser, addressed to it at
Five Giralda Farms, Madison, New Jersey 07940, Attn: Senior Vice President and
General Counsel, fax: (973) 660-7050, phone: (973) 660-5000, or at such other
address as the Purchaser shall have specified to the Company in writing, and (y)
if to the Company, addressed to it at 51 University, Seattle, Washington 98101,
Attn: Senior Vice President and General Counsel, fax: (206) 292-9271, phone:
(206) 587-0430, or at such other address as the Company shall have specified to
the Purchaser in writing. Any such notice or communication, if addressed, sent
and delivered as provided above, shall be deemed effective upon the actual
receipt of such notice or communication.

     13.7 Descriptive Headings

     The descriptive headings of the several paragraphs of this Agreement are
inserted for convenience only and do not constitute a part of this Agreement.

     13.8 Governing Law

     This Agreement shall be construed and enforced in accordance with, and the
rights of the Parties shall be governed by, the law of the State of New York.

     13.9 Counterparts

     This Agreement may be executed simultaneously in two (2) or more
counterparts, each of which shall be deemed an original, and it shall not be
necessary in making proof of this Agreement to produce or account for more than
one such counterpart.

     13.10 Severability

     Any provision of this Agreement that is prohibited or unenforceable in any
jurisdiction shall, as to such jurisdiction, be ineffective to the extent of
such prohibition or unenforceability without invalidating the remaining
provisions hereof, and any such prohibition or unenforceability in any
jurisdiction shall (to the full extent permitted by law) not invalidate or
render unenforceable such provision in any other jurisdiction.

     13.11 Publicity

     No party hereto shall issue any press release or otherwise make any
statements to any third party with respect to this Agreement, the issuance of
the Note or the other transactions contemplated hereby. Notwithstanding the
foregoing, the Company may issue a press release announcing this Agreement, the
issuance of the Note and the other transactions contemplated hereby (a) with the
consent of Purchaser, which consent may not be unreasonably withheld, or (b) as
required by law .



<PAGE>



     The execution hereof by the Purchaser shall constitute a contract among the
Company and the Purchaser for the uses and purposes herein above set forth.

                                      Very truly yours,

                                      IMMUNEX CORPORATION


                                      By
                                      Name:
                                     Title:

Agreed and accepted:

AMERICAN HOME PRODUCTS
CORPORATION


By
Name:
Title:





<PAGE>





                                    EXHIBIT A

     THE NOTE EVIDENCED HEREBY HAS NOT BEEN REGISTERED UNDER THE U.S. SECURITIES
ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR ANY STATE SECURITIES LAWS,
AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD WITHIN THE UNITED STATES OR TO, OR
FOR THE ACCOUNT OR BENEFIT OF, U.S. PERSONS EXCEPT AS SET FORTH IN THE FOLLOWING
SENTENCE. BY ITS ACQUISITION HEREOF, THE HOLDER (1) REPRESENTS THAT (A) IT IS A
"QUALIFIED INSTITUTIONAL BUYER" (AS DEFINED IN RULE 144A UNDER THE SECURITIES
ACT) OR (B) IT IS AN INSTITUTIONAL "ACCREDITED INVESTOR" (AS DEFINED IN RULE
501(A)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT) ("INSTITUTIONAL ACCREDITED
INVESTOR"); (2) AGREES THAT IT WILL NOT, PRIOR TO EXPIRATION OF THE HOLDING
PERIOD APPLICABLE TO SALES OF THE NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE
SECURITIES ACT (OR ANY SUCCESSOR PROVISION), RESELL OR OTHERWISE TRANSFER THE
NOTE EVIDENCED HEREBY OR THE COMMON STOCK ISSUABLE UPON CONVERSION OF SUCH NOTE
EXCEPT (A) TO IMMUNEX CORPORATION OR ANY SUBSIDIARY THEREOF, (B) TO A QUALIFIED
INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, (C)
TO AN INSTITUTIONAL ACCREDITED INVESTOR IN A DENOMINATION OF NO LESS THAN
$250,000 THAT, PRIOR TO SUCH TRANSFER, FURNISHES TO IMMUNEX CORPORATION (OR A
SUCCESSOR TRUSTEE, AS APPLICABLE), A SIGNED LETTER CONTAINING CERTAIN
REPRESENTATIONS AND AGREEMENTS RELATING TO THE RESTRICTIONS ON TRANSFER OF THE
NOTE EVIDENCED HEREBY (THE FORM OF WHICH LETTER IS ATTACHED AS ANNEX A), (D)
PURSUANT TO THE EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE
SECURITIES ACT (IF AVAILABLE) OR (E) PURSUANT TO A REGISTRATION STATEMENT WHICH
HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT (AND WHICH CONTINUES TO BE
EFFECTIVE AT THE TIME OF SUCH TRANSFER); (3) AGREES THAT PRIOR TO SUCH TRANSFER
(OTHER THAN A TRANSFER PURSUANT TO CLAUSE (2)(E) ABOVE), IT WILL FURNISH TO
IMMUNEX CORPORATION SUCH CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS
IT MAY REASONABLY REQUIRE TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT
TO AN EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT. IN CONNECTION WITH ANY TRANSFER OF THE NOTE
EVIDENCED HEREBY PRIOR TO THE EXPIRATION OF THE HOLDING PERIOD APPLICABLE TO
SALES OF THE NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE SECURITIES ACT (OR
ANY SUCCESSOR PROVISION), THE HOLDER MUST CHECK THE APPROPRIATE BOX SET FORTH ON
THE REVERSE HEREOF RELATING TO THE MANNER OF SUCH TRANSFER AND SUBMIT THIS
CERTIFICATE TO IMMUNEX CORPORATION. IF THE PROPOSED TRANSFEREE IS AN
INSTITUTIONAL ACCREDITED INVESTOR OR IS A PURCHASER WHO IS NOT A U.S. PERSON,
THE HOLDER MUST, PRIOR TO SUCH TRANSFER, FURNISH TO IMMUNEX CORPORATION, SUCH
CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS IT MAY REASONABLY REQUIRE
TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT TO AN EXEMPTION FROM, OR IN
A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES
ACT. THIS LEGEND WILL BE REMOVED UPON THE EARLIER OF THE TRANSFER OF THE NOTE
EVIDENCED HEREBY PURSUANT TO CLAUSE (2)(E) ABOVE OR UPON ANY TRANSFER OF THE
NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE SECURITIES ACT (OR ANY SUCCESSOR
PROVISION). AS USED HEREIN, THE TERMS "UNITED STATES" AND "UNITED STATES PERSON"
HAVE THE MEANINGS GIVEN TO THEM BY REGULATION S UNDER THE SECURITIES ACT.



<PAGE>



                               IMMUNEX CORPORATION

                    3% CONVERTIBLE SUBORDINATED NOTE DUE 2006



No.:  A-1         $450,000,000

     Immunex Corporation, a corporation duly organized and validly existing
under the laws of the State of Washington (herein called the "Company", which
term includes any successor corporation), for value received hereby promises to
pay to American Home Products Corporation or registered assigns, the principal
sum of Four Hundred Fifty Million Dollars ($450,000,000) on May 20, 2006, at the
office or agency of the Company, in such coin or currency of the United States
of America as at the time of payment shall be legal tender for the payment of
public and private debts, and to pay interest, semi-annually on April 30 and
October 31 of each year, commencing October 31, 1999, on said principal sum at
said office or agency, in like coin or currency, at the rate per annum of 3%,
until payment of said principal sum has been made. Interest on the Note will
accrue from the most recent date to which interest has been paid, or if no
interest has been paid, from May 20, 1999. The interest payable on the Note on
any April 30 or October 31 will be paid to the Person entitled thereto as it
appears in the Note register at the close of business on the record date, which
shall be the April 15 or October 15 (whether or not a Business Day) next
preceding such April 30 or October 31. Interest may, at the option of the
Company, be paid either (i) by check mailed to the registered address of such
Person or (ii) by transfer to an account maintained by such Person located in
the United States. Interest will be computed on the basis of a 360-day year of
twelve 30-day months.

     Reference is made to the further provisions of this Note set forth on the
reverse hereof, including, without limitation, provisions subordinating the
payment of principal of and premium, if any, and interest on the Note to the
prior payment in full of all Senior Indebtedness, as defined herein, and
provisions giving the holder of this Note the right to convert this Note into
Common Stock of the Company on the terms and subject to the limitations referred
to on the reverse hereof. Such further provisions shall for all purposes have
the same effect as though fully set forth at this place.

     This Note shall be deemed to be a contract made under the laws of the State
of New York, and for all purposes shall be construed in accordance with and
governed by the laws of said State.

     IN WITNESS WHEREOF, Immunex Corporation has caused this Note to be duly
executed under its corporate seal to be affixed or imported hereon.

                                              IMMUNEX CORPORATION


                                              By:
                                              Name:
                                              Title:



                                               Attest:
                                               Name:
                                               Title:

Dated:                              



<PAGE>



                         [FORM OF REVERSE SIDE OF NOTE]

                               IMMUNEX CORPORATION

                    3% CONVERTIBLE SUBORDINATED NOTE DUE 2006



     This Note is duly authorized and designated as its 3% Convertible
Subordinated Note due 2006 (herein called the "Note"), limited to the aggregate
principal amount of $450,000,000 pursuant to the Note Purchase Agreement dated
as of May 20, 1999 (herein called the "Note Purchase Agreement"), between the
Company and the Purchaser.

     In case an Event of Default, as defined in the Note Purchase Agreement,
shall have occurred and be continuing, the principal of, premium, if any, and
accrued interest on the Note may be declared, and upon said declaration shall
become, due and payable, in the manner, with the effect and subject to the
conditions provided in the Note Purchase Agreement.

     The Purchaser may waive any past default or Event of Default and its
consequences. Any such consent or waiver by the Purchaser shall be conclusive
and binding upon such holder and upon all future holders and owners of this Note
and any Notes which may be issued in exchange or substitute hereof, irrespective
of whether or not any notation thereof is made upon this Note or such other
Notes.

     The indebtedness evidenced by the Note is, to the extent and in the manner
provided in the Note Purchase Agreement, expressly subordinate and subject in
right of payment to the prior payment in full of all Senior Indebtedness of the
Company, as defined in the Note Purchase Agreement, whether outstanding at the
date of the Note Purchase Agreement or thereafter incurred, and this Note is
issued subject to the provisions of the Note Purchase Agreement with respect to
such subordination. Each holder of this Note, by accepting the same, agrees to
and shall be bound by such provisions and authorizes the Company on its behalf
to take such action as may be necessary or appropriate to effectuate the
subordination so provided and appoints the Company his attorney-in-fact for such
purpose.

     No reference herein to the Note Purchase Agreement and no provision of this
Note or of the Note Purchase Agreement shall alter or impair the obligation of
the Company, which is absolute and unconditional, to pay the principal of and
any premium and interest on this Note at the place, at the respective times, at
the rate and in the coin or currency herein prescribed.

     Interest on the Note shall be computed on the basis of a three hundred
sixty (360) day year.

     At the office or agency of the Company referred to on the face hereof, and
in the manner and subject to the limitations provided in the Note Purchase
Agreement, without payment of any service charge but with payment of a sum
sufficient to cover any tax or other governmental charge that may be imposed in
connection with any registration or exchange of the Note, the Note may be
exchanged for a like aggregate principal amount of Notes of other authorized
denominations, which may in turn be exchanged for a like aggregate principal
amount of Notes of other authorized denominations.

     The Note is not subject to redemption through the operation of any sinking
fund.

     Subject to the provisions of the Note Purchase Agreement, the holder hereof
has the right, at its option, at any time through the close of business on the
final maturity date of the Note to convert the principal hereof or any portion
of such principal in an amount of at least $50,000,000, and in increments of
$1,000,000 in excess thereof, into that number of shares of the Company's Common
Stock, as said shares shall be constituted at the date of conversion, obtained
by dividing the principal amount of this Note or portion thereof to be
converted, by $173.68 (the "Conversion Price") or such Conversion Price as
adjusted from time to time as provided in the Note Purchase Agreement, upon
surrender of this Note, together with a conversion notice as provided in the
Note Purchase Agreement, to the Company at the office or agency of the Company
maintained for that purpose in accordance with the terms of the Note Purchase
Agreement, and, unless the shares issuable on conversion are to be issued in the
same name as this Note, duly endorsed by, or accompanied by instruments of
transfer in form satisfactory to the Company duly executed by, the holder or by
his duly authorized attorney. No adjustment in respect of interest or dividends
will be made upon any conversion. No fractional shares will be issued upon any
conversion, but an adjustment in cash will be made, as provided in the Note
Purchase Agreement, in respect of any fraction of a share which would otherwise
be issuable upon the surrender of any Note or Notes for conversion. If the Note
(or any portion thereof) shall be surrendered for conversion pursuant to the
Note Purchase Agreement, the Company shall make an additional payment in a check
or cash to the Purchaser or holder thereof for accrued and unpaid interest, if
any, to, but excluding, the date of such conversion.

     Upon due presentment for registration of transfer of this Note at the
office or agency of the Company maintained for that purpose in accordance with
the terms of the Note Purchase Agreement, a new Note or Notes of authorized
denominations for an equal aggregate principal amount will be issued to the
transferee in exchange thereof; subject to the limitations provided in the Note
Purchase Agreement, without charge.

     The Company, any paying agent, any conversion agent and any Note registrar
may deem and treat the registered holder hereof as the absolute owner of this
Note (whether or not this note shall be overdue and notwithstanding any notation
of ownership or other writing hereon made by anyone other than the Company or
any Note registrar), for the purpose of receiving payment hereof, or on account
hereof, for the conversion hereof and for all other purposes, and neither the
Company nor any Trustee nor any other authenticating agent nor any paying agent
nor other conversion agent nor any Note registrar shall be affected by any
notice to the contrary. All payments made to or upon the order of such
registered holder shall, to the extent of the sum or sums paid, satisfy and
discharge liability for monies payable on this Note.

     No recourse for the payment of the principal of or any premium or interest
on this Note, or for any claim based hereon or otherwise in respect hereof; and
no recourse under or upon any obligation, covenant or agreement of the Company
in the Note Purchase Agreement or in any Note, or because of the creation of any
indebtedness represented thereby, shall be had against any incorporator,
shareholder, employee, agent, officer or director or subsidiary, as such, past,
present or future, of the Company or of any successor Person, either directly or
through the Company or any successor Person, whether by virtue of any
constitution, statute or rule of law or by the enforcement of any assessment or
penalty or otherwise, all such liability being, by acceptance hereof and as part
of the consideration for the issue hereof, expressly waived and released.

     This Note shall be deemed to be a contract made under the laws of New York,
and for all purposes shall be construed in accordance with the laws of New York.

     Terms used in this Note and defined in the Note Purchase Agreement are used
herein as therein defined.



<PAGE>



                                CONVERSION NOTICE



TO:  IMMUNEX CORPORATION

     The undersigned registered owner of this Note hereby irrevocably exercises
the option to convert this Note into shares of Common Stock of Immunex
Corporation in accordance with the terms of the Note Purchase Agreement referred
to in this Note, and directs that the shares issuable and deliverable upon such
conversion, together with any check in payment for fractional shares and any
Notes representing any unconverted principal amount hereof, be issued and
delivered to the registered holder hereof unless a different name has been
indicated below. If shares or any portion of this Note not converted are to be
issued in the name of a person other than the undersigned, the undersigned will
provide the appropriate information below. Any amount required to be paid to the
undersigned on account of interest accompanies this Note.

                                                     Dated:





                                                     Signature(s)





     Fill in the registration of shares of Common Stock to be issued, and Notes
to be delivered, other than to and in the name of the registered holder:



(Name)





(Street Address)





(City, State and Zip Code)





Please print name and address





Principal amount to be converted
(if less than all):  $





Social Security or Other Taxpayer
Identification Number:



<PAGE>



                                   ASSIGNMENT



     For value received _________________________ hereby sell(s), assign(s) and
transfer(s) unto _________________________ (Please insert social security or
other Taxpayer Identification Number of assignee) the within Note, and hereby
irrevocably constitutes and appoints _________________________ attorney to
transfer the said Note on the books of the Company, with full power of
substitution in the premises.

     In connection with any transfer of the Note within the United States or to,
or for the account of, U.S. persons (in each case as defined in Regulation S
under the Securities Act) and within the period prior to the expiration of the
holding period applicable to sales thereof under Rule 144(k) under the
Securities Act (or any successor provision) (other than any transfer pursuant to
a registration statement that has been declared effective under the Securities
Act), the undersigned confirms that such Note is being transferred:

     To Immunex Corporation or a subsidiary thereof; or

     Pursuant to and in compliance  with Rule 144A under the  Securities  Act of
1933, as amended; or

     To an Institutional Accredited Investor pursuant to and in compliance with
the Securities Act of 1933, as amended, in a minimum denomination of $100,000;
or

     Pursuant to and in  compliance  with Rule 144 under the  Securities  Act of
1933, as amended;

     and unless the box below is checked, the undersigned confirms that such
Note is not being transferred to an "affiliate" of the Company as defined in
Rule 144 under the Securities Act of 1933, as amended (an "Affiliate").

     The transferee is an Affiliate of the Company.

                                                     Dated:





<PAGE>



                                                     Signature(s)

     NOTICE: The signature of the conversion notice or the assignment must
correspond with the name as written upon the face of the Note in every
particular without alteration or enlargement or any change whatever.





<PAGE>



                                                                       Exhibit B


     Affiliate: The term "Affiliate" shall mean any Person directly or
indirectly controlling, controlled by or under direct or indirect control with
either the Company or the Purchaser, as the case may be. A Person shall be
deemed to control a corporation or other entity if such Person possesses,
directly or indirectly, the power to direct or cause the direction of the
management or policies of such corporation or other entity, whether through the
ownership of voting securities, by contract or otherwise. For purposes of this
Agreement, the Company and the Purchaser shall not be deemed to be Affiliates of
each other.

     Board of Directors: The term "Board of Directors" shall mean the Board of
Directors of the Company or a committee of such Board duly authorized to act for
it hereunder.

     Business Day: The term "Business Day" shall mean each Monday, Tuesday,
Wednesday, Thursday and Friday which is not a day on which the banking
institutions in The City of New York are authorized or obligated by law or
executive order to close or be closed.

     Conversion  Price:  The term  "Conversion  Price " shall  have the  meaning
specified in Section 8.4.

     Default:  The term "default"  shall mean any event that is, or after notice
or passage of time, or both, would be, an Event of Default.

     Designated Senior Indebtedness: The term "Designated Senior Indebtedness"
shall mean any Senior Indebtedness with an aggregate principal amount in excess
of Fifteen Million Dollars ($15 million) in which the instrument creating or
evidencing the same or the assumption or guarantee thereof (or related
agreements or documents to which the Company is a party) expressly provides that
such Senior Indebtedness shall be "Designated Senior Indebtedness" for purposes
of this Agreement (provided that such instrument, agreement or other document
may place limitations and conditions on the right of such Senior Indebtedness to
exercise the rights of Designated Senior Indebtedness). If any payment made to
any holder of any Designated Senior Indebtedness or its Representative with
respect to such Designated Senior Indebtedness is rescinded or must otherwise be
returned by such holder or Representative upon the insolvency, bankruptcy or
reorganization of the Company or otherwise, the reinstated Indebtedness of the
Company arising as a result of such rescission or return shall constitute
Designated Senior Indebtedness effective as of the date of such recission or
return.

     Event of Default: The term "Event of Default" shall mean any event
specified in Section 9.1(a), (b), (c), (d),(e), (f), (g), (h) or (i).

     Exchange Act: The term "Exchange Act " shall mean the Securities Exchange
Act of 1934, as amended, and the rules and regulations promulgated thereunder,
as in effect from time to time.

     Indebtedness: The term "Indebtedness" shall mean, with respect to any
Person, and without duplication, (a) all indebtedness, obligations and other
liabilities (contingent or otherwise) of such Person for borrowed money
(including obligations of the Company in respect of overdrafts, and any loans or
advances from banks, whether or not evidenced by notes or similar instruments,
and all commitment, standby and other fees due and payable to financial
institutions with respect to credit facilities available to such Person) or
evidenced by bonds, debentures, notes or similar instruments (whether or not the
recourse of the lender is to the whole of the assets of such Person or to only a
portion thereof), other than any account payable or other accrued current
liability or obligation incurred in the ordinary course of business in
connection with the obtaining of materials or services; (b) to the extent not
otherwise included in this definition, net obligation of such Person under
foreign exchange contracts, currency exchange agreements and interest rate
protection agreements, the amount of any such obligations to be equal at any
time to the termination value of such agreement or arrangement giving rise to
such obligation that would be payable by such Person at such time; (c) all
reimbursement obligations and other liabilities (contingent or otherwise) of
such Person with respect to letters of credit, bank guarantees or bankers'
acceptances; (d) all obligations and liabilities (contingent or otherwise) in
respect of leases of real or personal property or other assets of such Person
required, in conformity with generally accepted accounting principles, to be
accounted for as capitalized lease obligations on the balance sheet of such
Person; (e) all direct or indirect guaranties or similar agreements by such
Person in respect of, and obligations or liabilities (contingent or otherwise)
of such Person to purchase or otherwise acquire or otherwise assure a creditor
against loss in respect of, indebtedness, obligations or liabilities of another
Person of the kind described in clauses (a) through (d); (f) any indebtedness or
other obligations described in clauses (a) through (e) secured by any mortgage,
pledge, lien or other encumbrance existing on property which is owned or held by
such Person, regardless of whether the indebtedness or other obligation secured
thereby shall have been assumed by such Person; and (g) any and all deferrals,
renewals, extensions and refundings of, or amendments, modifications or
supplements to, any indebtedness, obligation or liability of the kind described
in clauses (a) through (f).

     LIBOR: The term "LIBOR" shall mean the per annum rate of interest published
from time to time by The Wall Street Journal as being the one-month London
Interbank Offered Rate (identified in The Wall Street Journal as the average of
interbank offered rates for one-month dollar deposits in the London market based
on quotations of five major banks for contracts entered into two (2) days prior
to the first Business Day of the month in which LIBOR is to be determined), or
if The Wall Street Journal shall for any reason cease or fail to publish a
one-month "LIBOR" rate, such other comparable interest rate index as the
Representative shall reasonably designate in writing to the Company as a
substitute therefor. If The Wall Street Journal quotes or publishes more than
one such one-month "LIBOR" rate, the highest of such rate will be used.

     LIBOR Rate: The term "LIBOR Rate" shall mean a rate per annum determined
for such month in accordance with the following formula (rounded upward to the
nearest 1/100th of 1%):

         LIBOR Rate =                                LIBOR             
                                    1.00 - LIBOR Reserve Percentage

     LIBOR Reserve Requirements: The term "LIBOR Reserve Requirements" shall
mean, for any month, the aggregate (without duplication) of the maximum rates
(expressed as a decimal fraction) of reserve requirements in effect on the first
day of such month (including, without limitation, basic, supplemental, marginal
and emergency reserves under any regulations of the Board of Governors of the
Federal Reserve System or other government authority having jurisdiction with
eurocurrency funding (currently referred to as "Eurocurrency Liabilities" in
Regulation D of such Board as the same is from time to time in effect, and all
official rulings and interpretations thereunder or thereof and any successor
regulation thereto) maintained by a member bank of such Federal Reserve System).

     Material Adverse Effect: The term "Material Adverse Effect" shall mean (a)
a material adverse change in, or a material adverse effect upon, the operations,
business, properties, assets, condition (financial or otherwise) or prospects of
the Company or the Company and its Subsidiaries taken as a whole; (b) a material
impairment of the ability of the Company or any Subsidiary to perform under this
Agreement or the Note and to avoid any Event of Default; or (c) a material
adverse effect upon the legality, validity, binding effect or enforceability
against the Company or any Subsidiary of this Agreement or the Note.

     Person: The term "Person" shall mean a corporation, an association, a
partnership, a limited liability corporation, an individual, a joint venture, a
joint stock company, a trust, an unincorporated organization or a government or
an agency or a political subdivision thereof.

     Representative: The term "Representative" shall mean the (a) indenture
trustee or other trustee, agent or representative for any Senior Indebtedness or
(b) with respect to any Senior Indebtedness that does not have any such trustee,
agent or other representative, (i) in the case of such Senior Indebtedness
issued pursuant to an agreement providing for voting arrangements as among the
holders or owners of such Senior Indebtedness, any holder or owner of such
Senior Indebtedness acting with the consent of the required Persons necessary to
bind such holders or owners of such Senior Indebtedness and (ii) in the case of
all other such Senior Indebtedness, the holder or owner of such Senior
Indebtedness.

     Securities Act: The term  "Securities Act" shall mean the Securities Act of
1933, as amended, and the rules and regulations promulgated thereunder.

     Senior Indebtedness: The term "Senior Indebtedness " shall mean the
principal of, premium, if any, interest (including all interest accruing
subsequent to the commencement of any bankruptcy or similar proceeding, whether
or not a claim for post-petition interest is allowable as a claim in any such
proceeding) on or in connection with, and all fees, costs, expenses and other
amounts accrued or due on or in connection with, Indebtedness of the Company,
whether outstanding on the date of this Agreement or thereafter created,
incurred, assumed, guaranteed or in effect guaranteed by the Company (including
all deferrals, renewals, extensions or refundings of, or amendments,
modifications or supplements to, the foregoing); provided, however, that Senior
Indebtedness will not include: (a) any Indebtedness which, in the instrument
creating or evidencing the same or pursuant to which the same is outstanding, it
is provided that the obligations in respect of such Indebtedness are not
superior in right or, or are subordinate to, payment of the Note; (b) any
obligation of the Company to any Subsidiary; (c) any liability for Federal,
state, foreign, local or other taxes owed or owing by the Company; (d) any
accounts payable or other liability to trade creditors arising in the ordinary
course of business (including guaranties thereof or instruments evidencing such
liabilities); (e) any Indebtedness, guarantee or obligation of the Company that
is expressly subordinate or junior in right of payment to any other
Indebtedness, guarantee or obligation of the Company; or (f) any capital stock.

     Significant Subsidiary: The term "Significant Subsidiary" shall mean, as of
any date of determination, a Subsidiary of the Company that would constitute a
"significant subsidiary" as such term is defined under Rule 1-02 of Regulation
S-X of the SEC.

     Subsidiary: The term "Subsidiary" shall mean, with respect to any Person,
(i) any corporation, association or other business entity of which more than
fifty percent (50%) of the total voting power of shares of capital stock
entitled (without regard to the occurrence of any contingency) to vote in the
election of directors, managers or trustees thereof is at the time owned or
controlled, directly or indirectly, by such Person or one or more of the other
subsidiaries of that Person (or a combination thereof) and (ii) any partnership
(a) the sole general partner or managing general partner of which is such Person
or a subsidiary of such Person or (b) the only general partners of which are
such Person or of one or more subsidiaries of such Person (or any combination
thereof).

     Trading Day:  The term  "Trading  Day" shall have the meaning  specified in
Section 8.5(h)(5).

     Trigger Event: The term "Trigger Event" shall have the meaning specified in
Section 8.5(d).





     THE NOTE EVIDENCED HEREBY HAS NOT BEEN REGISTERED UNDER THE U.S. SECURITIES
ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR ANY STATE SECURITIES LAWS,
AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD WITHIN THE UNITED STATES OR TO, OR
FOR THE ACCOUNT OR BENEFIT OF, U.S. PERSONS EXCEPT AS SET FORTH IN THE FOLLOWING
SENTENCE. BY ITS ACQUISITION HEREOF, THE HOLDER (1) REPRESENTS THAT (A) IT IS A
"QUALIFIED INSTITUTIONAL BUYER" (AS DEFINED IN RULE 144A UNDER THE SECURITIES
ACT) OR (B) IT IS AN INSTITUTIONAL "ACCREDITED INVESTOR" (AS DEFINED IN RULE
501(A)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT) ("INSTITUTIONAL ACCREDITED
INVESTOR"); (2) AGREES THAT IT WILL NOT, PRIOR TO EXPIRATION OF THE HOLDING
PERIOD APPLICABLE TO SALES OF THE NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE
SECURITIES ACT (OR ANY SUCCESSOR PROVISION), RESELL OR OTHERWISE TRANSFER THE
NOTE EVIDENCED HEREBY OR THE COMMON STOCK ISSUABLE UPON CONVERSION OF SUCH NOTE
EXCEPT (A) TO IMMUNEX CORPORATION OR ANY SUBSIDIARY THEREOF, (B) TO A QUALIFIED
INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, (C)
TO AN INSTITUTIONAL ACCREDITED INVESTOR IN A DENOMINATION OF NO LESS THAN
$250,000 THAT, PRIOR TO SUCH TRANSFER, FURNISHES TO IMMUNEX CORPORATION (OR A
SUCCESSOR TRUSTEE, AS APPLICABLE), A SIGNED LETTER CONTAINING CERTAIN
REPRESENTATIONS AND AGREEMENTS RELATING TO THE RESTRICTIONS ON TRANSFER OF THE
NOTE EVIDENCED HEREBY (THE FORM OF WHICH LETTER IS ATTACHED AS ANNEX A), (D)
PURSUANT TO THE EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE
SECURITIES ACT (IF AVAILABLE) OR (E) PURSUANT TO A REGISTRATION STATEMENT WHICH
HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT (AND WHICH CONTINUES TO BE
EFFECTIVE AT THE TIME OF SUCH TRANSFER); (3) AGREES THAT PRIOR TO SUCH TRANSFER
(OTHER THAN A TRANSFER PURSUANT TO CLAUSE (2)(E) ABOVE), IT WILL FURNISH TO
IMMUNEX CORPORATION SUCH CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS
IT MAY REASONABLY REQUIRE TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT
TO AN EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT. IN CONNECTION WITH ANY TRANSFER OF THE NOTE
EVIDENCED HEREBY PRIOR TO THE EXPIRATION OF THE HOLDING PERIOD APPLICABLE TO
SALES OF THE NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE SECURITIES ACT (OR
ANY SUCCESSOR PROVISION), THE HOLDER MUST CHECK THE APPROPRIATE BOX SET FORTH ON
THE REVERSE HEREOF RELATING TO THE MANNER OF SUCH TRANSFER AND SUBMIT THIS
CERTIFICATE TO IMMUNEX CORPORATION. IF THE PROPOSED TRANSFEREE IS AN
INSTITUTIONAL ACCREDITED INVESTOR OR IS A PURCHASER WHO IS NOT A U.S. PERSON,
THE HOLDER MUST, PRIOR TO SUCH TRANSFER, FURNISH TO IMMUNEX CORPORATION, SUCH
CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS IT MAY REASONABLY REQUIRE
TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT TO AN EXEMPTION FROM, OR IN
A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES
ACT. THIS LEGEND WILL BE REMOVED UPON THE EARLIER OF THE TRANSFER OF THE NOTE
EVIDENCED HEREBY PURSUANT TO CLAUSE (2)(E) ABOVE OR UPON ANY TRANSFER OF THE
NOTE EVIDENCED HEREBY UNDER RULE 144 UNDER THE SECURITIES ACT (OR ANY SUCCESSOR
PROVISION). AS USED HEREIN, THE TERMS "UNITED STATES" AND "UNITED STATES PERSON"
HAVE THE MEANINGS GIVEN TO THEM BY REGULATION S UNDER THE SECURITIES ACT.



<PAGE>



                               IMMUNEX CORPORATION

                    3% CONVERTIBLE SUBORDINATED NOTE DUE 2006



No.:  A-1         $450,000,000

     Immunex Corporation, a corporation duly organized and validly existing
under the laws of the State of Washington (herein called the "Company", which
term includes any successor corporation), for value received hereby promises to
pay to American Home Products Corporation or registered assigns, the principal
sum of Four Hundred Fifty Million Dollars ($450,000,000) on May 20, 2006, at the
office or agency of the Company, in such coin or currency of the United States
of America as at the time of payment shall be legal tender for the payment of
public and private debts, and to pay interest, semi-annually on April 30 and
October 31 of each year, commencing October 31, 1999, on said principal sum at
said office or agency, in like coin or currency, at the rate per annum of 3%,
until payment of said principal sum has been made. Interest on the Note will
accrue from the most recent date to which interest has been paid, or if no
interest has been paid, from May 20, 1999. The interest payable on the Note on
any April 30 or October 31 will be paid to the Person entitled thereto as it
appears in the Note register at the close of business on the record date, which
shall be the April 15 or October 15 (whether or not a Business Day) next
preceding such April 30 or October 31. Interest may, at the option of the
Company, be paid either (i) by check mailed to the registered address of such
Person or (ii) by transfer to an account maintained by such Person located in
the United States. Interest will be computed on the basis of a 360-day year of
twelve 30-day months.

     Reference is made to the further provisions of this Note set forth on the
reverse hereof, including, without limitation, provisions subordinating the
payment of principal of and premium, if any, and interest on the Note to the
prior payment in full of all Senior Indebtedness, as defined herein, and
provisions giving the holder of this Note the right to convert this Note into
Common Stock of the Company on the terms and subject to the limitations referred
to on the reverse hereof. Such further provisions shall for all purposes have
the same effect as though fully set forth at this place.

     This Note shall be deemed to be a contract made under the laws of the State
of New York, and for all purposes shall be construed in accordance with and
governed by the laws of said State.

     IN WITNESS WHEREOF, Immunex Corporation has caused this Note to be duly
executed under its corporate seal to be affixed or imported hereon.

                                   IMMUNEX CORPORATION


                                   By:                                       
                                   Name:                                      
                                   Title:                                    



                                    Attest:                                  
                                    Name:                                    
                                    Title:                                   

Dated:                              



<PAGE>



                         [FORM OF REVERSE SIDE OF NOTE]

                               IMMUNEX CORPORATION

                    3% CONVERTIBLE SUBORDINATED NOTE DUE 2006



     This Note is duly authorized and designated as its 3% Convertible
Subordinated Note due 2006 (herein called the "Note"), limited to the aggregate
principal amount of $450,000,000 pursuant to the Note Purchase Agreement dated
as of May 20, 1999 (herein called the "Note Purchase Agreement"), between the
Company and the Purchaser.

     In case an Event of Default, as defined in the Note Purchase Agreement,
shall have occurred and be continuing, the principal of, premium, if any, and
accrued interest on the Note may be declared, and upon said declaration shall
become, due and payable, in the manner, with the effect and subject to the
conditions provided in the Note Purchase Agreement.

     The Purchaser may waive any past default or Event of Default and its
consequences. Any such consent or waiver by the Purchaser shall be conclusive
and binding upon such holder and upon all future holders and owners of this Note
and any Notes which may be issued in exchange or substitute hereof, irrespective
of whether or not any notation thereof is made upon this Note or such other
Notes.

     The indebtedness evidenced by the Note is, to the extent and in the manner
provided in the Note Purchase Agreement, expressly subordinate and subject in
right of payment to the prior payment in full of all Senior Indebtedness of the
Company, as defined in the Note Purchase Agreement, whether outstanding at the
date of the Note Purchase Agreement or thereafter incurred, and this Note is
issued subject to the provisions of the Note Purchase Agreement with respect to
such subordination. Each holder of this Note, by accepting the same, agrees to
and shall be bound by such provisions and authorizes the Company on its behalf
to take such action as may be necessary or appropriate to effectuate the
subordination so provided and appoints the Company his attorney-in-fact for such
purpose.

     No reference herein to the Note Purchase Agreement and no provision of this
Note or of the Note Purchase Agreement shall alter or impair the obligation of
the Company, which is absolute and unconditional, to pay the principal of and
any premium and interest on this Note at the place, at the respective times, at
the rate and in the coin or currency herein prescribed.

     Interest on the Note shall be computed on the basis of a three hundred
sixty (360) day year.

     At the office or agency of the Company referred to on the face hereof, and
in the manner and subject to the limitations provided in the Note Purchase
Agreement, without payment of any service charge but with payment of a sum
sufficient to cover any tax or other governmental charge that may be imposed in
connection with any registration or exchange of the Note, the Note may be
exchanged for a like aggregate principal amount of Notes of other authorized
denominations, which may in turn be exchanged for a like aggregate principal
amount of Notes of other authorized denominations.

     The Note is not subject to redemption through the operation of any sinking
fund.

     Subject to the provisions of the Note Purchase Agreement, the holder hereof
has the right, at its option, at any time through the close of business on the
final maturity date of the Note to convert the principal hereof or any portion
of such principal in an amount of at least $50,000,000, and in increments of
$1,000,000 in excess thereof, into that number of shares of the Company's Common
Stock, as said shares shall be constituted at the date of conversion, obtained
by dividing the principal amount of this Note or portion thereof to be
converted, by $173.68 (the "Conversion Price") or such Conversion Price as
adjusted from time to time as provided in the Note Purchase Agreement, upon
surrender of this Note, together with a conversion notice as provided in the
Note Purchase Agreement, to the Company at the office or agency of the Company
maintained for that purpose in accordance with the terms of the Note Purchase
Agreement, and, unless the shares issuable on conversion are to be issued in the
same name as this Note, duly endorsed by, or accompanied by instruments of
transfer in form satisfactory to the Company duly executed by, the holder or by
his duly authorized attorney. No adjustment in respect of interest or dividends
will be made upon any conversion. No fractional shares will be issued upon any
conversion, but an adjustment in cash will be made, as provided in the Note
Purchase Agreement, in respect of any fraction of a share which would otherwise
be issuable upon the surrender of any Note or Notes for conversion. If the Note
(or any portion thereof) shall be surrendered for conversion pursuant to the
Note Purchase Agreement, the Company shall make an additional payment in a check
or cash to the Purchaser or holder thereof for accrued and unpaid interest, if
any, to, but excluding, the date of such conversion.

     Upon due presentment for registration of transfer of this Note at the
office or agency of the Company maintained for that purpose in accordance with
the terms of the Note Purchase Agreement, a new Note or Notes of authorized
denominations for an equal aggregate principal amount will be issued to the
transferee in exchange thereof; subject to the limitations provided in the Note
Purchase Agreement, without charge.

     The Company, any paying agent, any conversion agent and any Note registrar
may deem and treat the registered holder hereof as the absolute owner of this
Note (whether or not this note shall be overdue and notwithstanding any notation
of ownership or other writing hereon made by anyone other than the Company or
any Note registrar), for the purpose of receiving payment hereof, or on account
hereof, for the conversion hereof and for all other purposes, and neither the
Company nor any Trustee nor any other authenticating agent nor any paying agent
nor other conversion agent nor any Note registrar shall be affected by any
notice to the contrary. All payments made to or upon the order of such
registered holder shall, to the extent of the sum or sums paid, satisfy and
discharge liability for monies payable on this Note.

     No recourse for the payment of the principal of or any premium or interest
on this Note, or for any claim based hereon or otherwise in respect hereof; and
no recourse under or upon any obligation, covenant or agreement of the Company
in the Note Purchase Agreement or in any Note, or because of the creation of any
indebtedness represented thereby, shall be had against any incorporator,
shareholder, employee, agent, officer or director or subsidiary, as such, past,
present or future, of the Company or of any successor Person, either directly or
through the Company or any successor Person, whether by virtue of any
constitution, statute or rule of law or by the enforcement of any assessment or
penalty or otherwise, all such liability being, by acceptance hereof and as part
of the consideration for the issue hereof, expressly waived and released.

     This Note shall be deemed to be a contract made under the laws of New York,
and for all purposes shall be construed in accordance with the laws of New York.

     Terms used in this Note and defined in the Note Purchase Agreement are used
herein as therein defined.



<PAGE>



                                CONVERSION NOTICE



TO:  IMMUNEX CORPORATION

     The undersigned registered owner of this Note hereby irrevocably exercises
the option to convert this Note into shares of Common Stock of Immunex
Corporation in accordance with the terms of the Note Purchase Agreement referred
to in this Note, and directs that the shares issuable and deliverable upon such
conversion, together with any check in payment for fractional shares and any
Notes representing any unconverted principal amount hereof, be issued and
delivered to the registered holder hereof unless a different name has been
indicated below. If shares or any portion of this Note not converted are to be
issued in the name of a person other than the undersigned, the undersigned will
provide the appropriate information below. Any amount required to be paid to the
undersigned on account of interest accompanies this Note.

                                                     Dated:





                                                     Signature(s)





     Fill in the registration of shares of Common Stock to be issued, and Notes
to be delivered, other than to and in the name of the registered holder:



(Name)





(Street Address)





(City, State and Zip Code)





Please print name and address





Principal amount to be converted
(if less than all):  $





Social Security or Other Taxpayer
Identification Number:



<PAGE>



                                   ASSIGNMENT



     For value received _________________________ hereby sell(s), assign(s) and
transfer(s) unto _________________________ (Please insert social security or
other Taxpayer Identification Number of assignee) the within Note, and hereby
irrevocably constitutes and appoints _________________________ attorney to
transfer the said Note on the books of the Company, with full power of
substitution in the premises.

     In connection with any transfer of the Note within the United States or to,
or for the account of, U.S. persons (in each case as defined in Regulation S
under the Securities Act) and within the period prior to the expiration of the
holding period applicable to sales thereof under Rule 144(k) under the
Securities Act (or any successor provision) (other than any transfer pursuant to
a registration statement that has been declared effective under the Securities
Act), the undersigned confirms that such Note is being transferred:

     To Immunex Corporation or a subsidiary thereof; or

     Pursuant to and in compliance  with Rule 144A under the  Securities  Act of
1933, as amended; or

     To an Institutional Accredited Investor pursuant to and in compliance with
the Securities Act of 1933, as amended, in a minimum denomination of $100,000;
or

     Pursuant to and in  compliance  with Rule 144 under the  Securities  Act of
1933, as amended;

     and unless the box below is checked, the undersigned confirms that such
Note is not being transferred to an "affiliate" of the Company as defined in
Rule 144 under the Securities Act of 1933, as amended (an "Affiliate").

     The transferee is an Affiliate of the Company.

                                                     Dated:





<PAGE>



                                  Signature(s)

     NOTICE: The signature of the conversion notice or the assignment must
correspond with the name as written upon the face of the Note in every
particular without alteration or enlargement or any change whatever.





                                 AMENDMENT NO. 1
                             to AMENDED AND RESTATED
                              GOVERNANCE AGREEMENT


     This Amendment No. 1 ("Amendment No. 1") is made this 20th day of May, 1999
(the "Amendment Effective Date") by and between AMERICAN CYANAMID COMPANY, a
corporation organized and existing under the laws of the State of Maine
("CYANAMID") and a wholly-owned subsidiary of AMERICAN HOME PRODUCTS
CORPORATION, a corporation organized and existing under the laws of the State of
Delaware and having its principal office at Five Giralda Farms, Madison, New
Jersey 07940 ("AHPC") and IMMUNEX CORPORATION, a corporation organized and
existing under the laws of the State of Washington and having its principal
office at 51 University Street, Seattle, Washington 98101 ("IMMUNEX"), and
amends the Amended and Restated Governance Agreement dated as of December 15,
1992, among American Cyanamid Company, Immunex Corporation and Lederle Oncology
Corporation (the "Governance Agreement").

     WHEREAS, AHPC and IMMUNEX have entered into a certain Note Purchase
Agreement dated as of the date hereof, pursuant to which IMMUNEX has issued, and
AHPC has purchased, a 3% Convertible Subordinated Note due 2006 in the principal
amount of $450 million ("Note"), which Note is convertible, in whole or in part,
into common stock of IMMUNEX at a specified price per share, subject to
adjustment in certain circumstances;

     WHEREAS, AHPC and IMMUNEX have agreed that the shares that are subject to
issuance to AHPC upon conversion of the Note may be included in the calculation
of AHPC's and CYANAMID's ownership of Immunex common stock for certain purposes
under the Governance Agreement;

     NOW THEREFORE, in consideration of the mutual covenants contained herein,
and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the parties hereto, each intending to be legally
bound, hereby agree as follows:

     1. All initially capitalized terms used herein and not defined shall have
the meanings set forth in the Governance Agreement.

     2. Article II of the Governance Agreement shall be amended to add the
following new provision, Section 2.03, as follows:

     2.03 Common Stock issuable upon Conversion of Note. The Common Stock
issuable upon conversion of the Note issued by the Company and purchased by
American Home Products Corporation ("AHPC") pursuant to the Note Purchase
Agreement dated as of May 20, 1999 shall, at the option of Cyanamid, regardless
of whether the Note is converted by AHPC so long as AHPC or its Affiliates hold
the Note, be included in (i) "Cyanamid's Interest" for purposes of Article IV;
(ii) Cyanamid's "Pro Rata Share" for purposes of Section 2.01; (iii) Cyanamid's
"Owned Shares" for purposes of Section 2.02 (and shall be deemed to be issued
and outstanding as of the Quarterly Date immediately preceding the effective
date of the Note Purchase Agreement) ; and (iv) "Registrable Securities" for
purposes of Article VI.

     3. Article V of the Governance Agreement shall be amended to add the
following new provision, Section 5.01(h), as follows:

     (h) The Note issued by the Company and purchased by AHPC pursuant to the
Note Purchase Agreement dated as of May 20, 1999 shall not be deemed to be an
interest in New Shares for purposes of Section 5.01(c) hereof and AHPC shall
have the right to transfer such Note in accordance with the terms of the Note
Purchase Agreement. Notwithstanding the foregoing, however, the Common Stock
issuable upon conversion of such Note shall, when and if issued, be deemed to be
New Shares for purposes of this Article V.

     4. The first clause of Section 6.03(d) shall be deleted in its entirety and
replaced as follows:

     (d) The Company shall not be obligated to effect more than three
registrations pursuant to this Section 6.03;

     5. Except as otherwise set forth in this Amendment No. 1, all other terms
and provisions of the Governance Agreement shall remain in full force and
effect.

     6. This  Amendment  No. 1 may be  executed in  counterparts,  each of which
shall be deemed an original and all of which shall  constitute  together one and
the same instrument.


<PAGE>



     IN WITNESS WHEREOF, the parties hereto have executed this Amendment No. 1
as of the day and year first above written.

                                            IMMUNEX CORPORATION


                                            By:________________________________
                                               Edward V. Fritzky
                                               Chairman and Chief 
                                               Executive Officer


                                            AMERICAN CYANAMID COMPANY


                                            By:________________________________

                                                Name:__________________________

                                                Title:_________________________


                                            AMERICAN HOME PRODUCTS CORPORATION


                                            By:________________________________

                                                Name:__________________________

                                                Title:_________________________





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