AXP INVESTMENT SERIES INC
497, 2000-07-28
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                     PROSPECTUS SUPPLEMENT - July 28, 2000*

AXP Mutual (Nov. 29, 1999 revised as of June 26, 2000) S-6326-99 T (6/00)

The second paragraph of the "MANAGEMENT" section is revised as follows:

Michael  Manns joined AEFC in 1994 as an equity  fundamental  analyst.  He began
managing  the  equity  portion of the  Portfolio  and  making  asset  allocation
decisions in June 2000. He also began managing institutional equity accounts for
American  Express  Asset  Management  Group  Inc.  in 1995 and was  promoted  to
portfolio manager in 1997.




S-6326-21 A (7/00)
*Valid until next prospectus update
Destroy Nov. 29, 2000





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