AXP INVESTMENT SERIES INC
497, 2000-08-14
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PROSPECTUS SUPPLEMENT - August 14, 2000*

AXP Mutual (Nov. 29, 1999 revised as of June 26, 2000) S-6326-99 T (6/00)

The "INVESTMENT STRATEGY" section on page 3p is revised as follows:

The Fund's assets  primarily are invested in a combination  of common stocks and
senior securities (preferred stocks and debt obligations).  The Fund will invest
(1) no more than 65% of its total assets in common  stocks,  (2) at least 35% of
its total  assets  in  senior  securities,  convertible  securities,  derivative
instruments  and  money  market  instruments,  and (3) at least 25% of its total
assets in debt  securities  and  convertible  securities.  The Fund will utilize
derivative  instruments  (such as futures,  options and forward  contracts)  and
when-issued  securities  to  produce  incremental  earnings,  to hedge  existing
positions and to increase flexibility.  The Fund's potential losses from the use
of these instruments could extend beyond its initial investment.

The selection of common stocks and senior  securities are the primary  decisions
in building the investment portfolio.

In pursuit of the Fund's goal,  American Express Financial  Corporation  (AEFC),
the Fund's investment manager, chooses equity investments by:

o    Considering  opportunities and risks by reviewing overall market conditions
     and industry outlook.

o    Identifying large companies with strong,  sustainable earnings growth based
     upon:

-        effective management (considering overall performance),

-        competitive market position, and

-        financial strength.

o    Selecting high quality  companies that offer long-term  growth based upon a
     combination of current valuation,  anticipated earnings growth, sustainable
     competitive positioning and industry dynamics.

(The remainder of the section on page 4p was not modified.)






S-6326-31 A (8/00)
*Valid until next prospectus update
 Destroy Nov. 29, 2000




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