HOECHST MARION ROUSSEL INC
SC 13D, 1996-03-22
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                  SCHEDULE 13D

                                        

                   Under the Securities Exchange Act of 1934




                            LYNX THERAPEUTICS, INC.
                          ----------------------------
                                (Name of Issuer)


                     Common Stock par value $.001 per share
- ---------------------------------------------------------------------------
                         (Title of Class of Securities)


                                  551812 30 8
                               -----------------
                                 (CUSIP Number)


William K. Hoskins, Esq.                         Harry R. Benz
General Counsel                                  Hoechst Corporation
Hoechst Marion Roussel, Inc.                     Route 202-206
10236 Marion Park Drive                          P.O. Box 2500
Kansas City, Missouri 64137-1405                 Somerville, NJ 08876-1258
(816) 966-4000                                   (517) 636-1000
- ---------------------------------------------------------------------------
                 (Name, Address and Telephone Number of Person
               Authorized to Receive Notices and Communications)



                                October 2, 1995
            -------------------------------------------------------
            (Date of Event Which Requires Filing of This Statement)



If the filing person has previously filed a statement on Schedule 13G to
report the acquisition which is the subject of this Schedule 13D, and is
filing this schedule because of Rule 13d-1(b)(4)(i)(A) or (B), check the
following box.  [  ]

Check the following box if a fee is being paid with this statement [ X ].


                                  Page 1 of 16

                          Exhibit Index is at Page 10



<PAGE>                                                                2
CUSIP No.  551812 30 8
___________________________________________________________________________

1)   Name of Reporting Person and its         Hoechst Marion Roussel, Inc.
     I.R.S. Identification Number                 44-0565557
___________________________________________________________________________

2)   Check the Appropriate Box if                                (a)[   ]
     a Member of a Group                                         (b)[ X ]
___________________________________________________________________________

3)   SEC Use Only
___________________________________________________________________________

4)   Source of Funds                                                  WC
___________________________________________________________________________

5)   Check Box if Disclosure of Legal                               [  ]
     Proceedings is Required Pursuant
     to Items 2(d) or 2(e)
___________________________________________________________________________
  

6)   Citizenship or Place of Organization                          Delaware
___________________________________________________________________________
     
               7)   Sole Voting Power                              400,000*
Number of      ____________________________________________________________
Shares
Beneficially   8)   Shared Voting Power                                   0
Owned by       ____________________________________________________________
Each
Reporting      9)   Sole Dispositive Power                         400,000*
Person With    ____________________________________________________________

               10)  Shared Dispositive Power                              0
___________________________________________________________________________

11)  Aggregate Amount Beneficially Owned                           400,000*
     by Each Reporting Person
___________________________________________________________________________

12)  Check Box If the Aggregate Amount                                 [  ]
     in Row (11) Excludes Certain Shares
___________________________________________________________________________

13)  Percent of Class Represented                                     14.6%
     by Amount in Row (11)
___________________________________________________________________________

14)  Type of Reporting Person                                            CO
___________________________________________________________________________

* Does not include an undetermined number of shares the reporting person is
obligated to purchase upon the happening of a future event - see Item 3.





<PAGE>                                                                3
CUSIP No.  551812 30 8
___________________________________________________________________________

1)   Name of Reporting Person and its              Hoechst Corporation
     I.R.S. Identification Number                  22-1862783
___________________________________________________________________________

2)   Check the Appropriate Box if                                  (a)[   ]
     a Member of a Group                                           (b)[ X ]
___________________________________________________________________________

3)   SEC Use Only
___________________________________________________________________________

4)   Source of Funds                                         Not applicable
___________________________________________________________________________

5)   Check Box if Disclosure of Legal                                  [  ]
     Proceedings is Required Pursuant
     to Items 2(d) or 2(e)
___________________________________________________________________________ 


6)   Citizenship or Place of Organization                          Delaware
___________________________________________________________________________
     
               7)   Sole Voting Power                              400,000*
Number of      ____________________________________________________________
Shares
Beneficially   8)   Shared Voting Power                                   0
Owned by       ____________________________________________________________
Each
Reporting      9)   Sole Dispositive Power                         400,000*
Person With    ____________________________________________________________

               10)  Shared Dispositive Power                              0
___________________________________________________________________________

11)  Aggregate Amount Beneficially Owned                           400,000*
     by Each Reporting Person
___________________________________________________________________________

12)  Check Box If the Aggregate Amount                                 [  ]
     in Row (11) Excludes Certain Shares
___________________________________________________________________________

13)  Percent of Class Represented                                     14.6%
     by Amount in Row (11)
___________________________________________________________________________

14)  Type of Reporting Person                                            CO
___________________________________________________________________________

* Does not include an undetermined number of shares the reporting person is
obligated to purchase upon the happening of a future event - see Item 3.




<PAGE>                                                                4
ITEM 1.   SECURITY AND ISSUER.
- -------   --------------------

     The securities to which this Schedule relates are shares of common
stock, par value $0.001 per share ("Common Stock"), of Lynx Therapeutics,
Inc., a Delaware corporation (the "Issuer").  All references herein to
numbers of shares of Common Stock reflect a one-for-ten reverse stock split
effective February 5, 1996.  The Issuer's principal executive offices are
at 3832 Bay Center Place, Hayward, CA 94545.

ITEM 2.   IDENTITY AND BACKGROUND.
- -------   ------------------------

     (a) - (c), (f)  This Schedule is filed on behalf of Hoechst Marion
Roussel, Inc., a Delaware corporation ("HMRI"), with a principal place of
business and principal office located at 10236 Marion Park Drive, Kansas
City, Missouri 64137-1405.  The principal business of HMRI is the
discovery, development, manufacturing, marketing, and sale of pharmaceuti-
cal compounds for the treatment of human diseases.  Information as to the
executive officers and directors of HMRI is set forth in Exhibit 99.E
hereto.

     This Schedule also is filed on behalf of Hoechst Corporation, a
Delaware corporation ("HCorp"), and wholly owned subsidiary of Hoechst
Aktiengesellschaft, a German corporation ("Hoechst AG").  HCorp is a
holding company for most of the U.S. operations of Hoechst AG, a
multinational pharmaceutical and chemical company headquartered in
Frankfurt, Germany.  The principal place of business and principal office
of HCorp is Route 202-206, Somerville, New Jersey 08876-1258.  Information
as to the executive officers and directors of HCorp and Hoechst AG is set
forth in Exhibit 99.F hereto.

     HCorp beneficially owns 98.2% of the outstanding common stock of HMRI
and is filing this Schedule solely with respect to its potential deemed
indirect ownership of HMRI's holdings of the securities.

     (d) - (e)  During the last five years, neither HMRI, HCorp, nor, to
their knowledge, any of the persons listed in Exhibits 99.E and 99.F
hereto, has been convicted in a criminal proceeding (excluding traffic
violations and similar misdemeanors).  During the last five years, neither
HMRI nor HCorp nor, to their knowledge, any of the persons listed in
Exhibits 99.E and 99.F hereto, has been a party to any civil proceeding of
a judicial or administrative body of competent jurisdiction as a result of
which any of them was or is subject to a judgment, decree, or final order
enjoining future violation of, or prohibiting or mandating activities
subject to, federal or state securities laws or finding any violation with
respect to such laws.  

ITEM 3.   SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION.
- -------   --------------------------------------------------

     HMRI and the Issuer have entered into a Series D Convertible Preferred
Stock Purchase Agreement dated October 2, 1995 (the "Stock Purchase
Agreement") providing for the purchase by HMRI of 400,000 shares of Series
D Convertible Preferred Stock (the "Shares") for $5,000,000 and the
subsequent purchase by HMRI of additional shares of the Issuer's preferred
stock or Common Stock for an aggregate purchase price of $10,000,000 (the
"Additional Shares") upon achievement by the Issuer of a Practical
Application Milestone defined in the Technology Development and Services
<PAGE>                                                                5
Agreement dated October 2, 1995, by and between the Issuer, HMRI, and
Hoechst AG (the "Technology Agreement").  The source of funds for the
purchase price of $5,000,000 for the Shares is, and of $10,000,000 for the
Additional Shares is expected to be, the working capital of HMRI.  None of
such funds are expected to be borrowed or otherwise obtained for the
purpose of acquiring the Shares or the Additional Shares.

ITEM 4.   PURPOSE OF TRANSACTION.
- -------   -----------------------

     The Stock Purchase Agreement provides for the acquisition of the
Shares and the Additional Shares by HMRI in connection with a technology
development effort described in the Technology Agreement.  The Technology
Agreement provides for HMRI and Hoechst AG (hereinafter sometimes referred
to together as "Hoechst") to provide certain immediate funding for the
development of a proprietary technology of the Issuer and certain
additional funding when the Issuer demonstrates the technology is ready for
practical application (the "Practical Application Milestone").  In return,
the Issuer will provide Hoechst with early, preferred access to the
Issuer's services applying the technology to biological samples provided by
Hoechst.  Upon payment of an additional amount, Hoechst will be entitled to
receive from the Issuer certain additional services applying the technology
for an initial subscription period of at least twelve months.  Hoechst will
have the right to renew its subsciption for successive one-year periods by
paying an additional sum each year.  Hoechst also will have the right to
purchase from the Issuer certain additional services applying the
technology.  

     The descriptions of the Stock Purchase Agreement and the Technology
Agreement are qualified in their entirety by reference to such agreements,
copies of which are set forth as Exhibits 99.A and 99.B hereto.

     Neither HMRI, HCorp, nor Hoechst AG currently has any plans or
proposals that relate to or would result in the acquisition by any person
of additional shares of Common Stock other than the Shares and the
Additional Shares (upon achievement of the Practical Application
Milestone), or the disposition of any of the Shares or the Additional
shares.  However, any of such persons may elect to acquire or dispose of
securities of the Issuer in the future depending on its evaluation of the
Issuer's business, prospects, and financial condition, the market for the
Common Stock, other opportunities available to Hoechst, prospects for
Hoechst's own businesses, general economic conditions, money and stock
market conditions, and other future developments.  

     Except as set forth in this Schedule and as may be contemplated in the
Stock Purchase Agreement or the Technology Agreement, neither HMRI, HCorp,
nor Hoechst AG has any plans or proposals that relate to or would result in
any of the events described in paragraphs (a) through (j) of this Item.

ITEM 5.   INTEREST IN SECURITIES OF THE ISSUER.
- -------   -------------------------------------

     (a)  The Shares represent approximately 14.6% of the Issuer's Common
Stock outstanding at December 31, 1995 on a fully-diluted basis.  The
Shares and Additional Shares together would represent approximately 25.5%
of the Issuer's outstanding Common Stock if the Additional Shares were
issued.  Except as may be set forth in any subsequent amendment to this
Schedule, neither Hoechst AG nor HCorp, nor any executive officer or
director of Hoechst AG, HMRI, or HCorp, beneficially owns any of the Shares
<PAGE>                                                                6
or any other shares of Common Stock other than through their beneficial
ownership, if any, of stock of Hoechst AG, HCorp, or HMRI.  HCorp, which is
a wholly-owned subsidiary of Hoechst AG, beneficially owns more than 98% of
the outstanding stock of HMRI.

     (b)  HMRI has sole power to vote and to dispose of the Shares (and,
when and if issued, the Additional Shares).  Neither Hoechst AG, HCorp, nor
any executive officer or director of either HMRI, HCorp, or Hoechst AG has
any power to vote or to direct the vote, or to dispose of or to direct the
disposition of, the Shares (or, when issued, the Additional Shares) except
to the extent that Hoechst AG, HCorp, or any such executive officer or
director may be deemed to have any such power by reason of such person's
relationship to or position with HMRI, HCorp, or Hoechst AG.

     (c)  None.  

     (d)  None.

     (e)  Not applicable.

ITEM 6.   CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS, OR RELATIONSHIPS WITH
- -------   RESPECT TO SECURITIES OF THE ISSUER.
          ------------------------------------

     Other than the Stock Purchase Agreement, and an Amended and Restated
Investor Rights Agreement dated as of November 1, 1995 (the "Investor
Rights Agreement") to which HMRI and the Issuer are parties with purchasers
of the Issuer's Series B Convertible Preferred Stock and Series C
Convertible Preferred Stock, there are no contracts, arrangements,
understandings or relationships between or among HMRI, HCorp, and/or
Hoechst AG and any other person with respect to any securities of the
Issuer.  

     The Stock Purchase Agreement provides for the purchase from the Issuer
by HMRI of 400,000 shares of Series D Convertible Preferred Stock at $12.50
per share and for the subsequent purchase by HMRI of the Additional Shares
for $10,000,000.  The Additional Shares will consist of either (i) 400,000
shares of preferred stock having terms similar to the Shares for a price of
$25.00 per share or, (ii) if the Shares have been converted into Common
Stock, the number of additional shares of Common Stock determined by
dividing $10,000,000 by the greater of $25.00 per share or the ten-day
average closing price for the Common Stock.  

     The shares of Series D Convertible Preferred Stock (the "Series D
Stock") comprising the Shares are convertible into Common Stock for the
option of the holder, or automatically upon the first to occur of (i) the
closing of an underwritten public offering of Common Stock at an aggregate
offering price of at least $15,000,000, (ii) the vote or consent of the
holders of a majority of the outstanding Series D Stock; or (iii) the
conversion into Common Stock of all of the outstanding shares of the
Issuer's Series B Convertible Preferred Stock and Series C Convertible
Preferred Stock.  Initially, the conversion ratio is one share of Series D
Stock for one share of Common Stock, with the conversion ratio subject to
adjustment upon the happening of certain dilutive events, including
combinatons or consolidations of Common Stock, stock dividends,
reclassifications,and distributions, and the issuance of additional shares
of Common Stock at a price lower than the conversion price of the Series D 



<PAGE>                                                                7
Stock, excluding Common Stock issued upon conversion of certain of the
Issuer's preferred stock or upon exercise of certain options, warrants, or
rights.

     The Investor Rights Agreement provides for the registration for sale
to the public of the shares of Common Stock into which the Shares are
convertible upon request by HMRI either (i) incidental to a registration of
Common Stock on behalf of the Issuer ("Piggyback Rights"), (ii) for an
offering of at least 500,000 shares of Common Stock or a lesser number of
shares having an anticipated aggregate offering price of at least
$10,000,000 ("Demand Rights"), once upon request by HMRI alone plus up to
three additional registrations in cooperation with holders of other
securities covered by the Investor Rights Agreement, provided that the
Demand Rights are not effective until the earlier of October 31, 1996, or
three months after the effective date of a registration statement for an
underwritten public offering by the Issuer having aggregate proceeds of at
least $15,000,000, or (iii) on Form S-3 of the Securities and Exchange
Commission for a number of shares having an anticipated aggregate offering
price of at least $500,000 ("S-3 Rights").  Demand Rights, Piggyback
Rights, and S-3 Rights are subject to numerous conditions.  Demand Rights
and S-3 Rights terminate on June 1, 2006.

     The Investor Rights Agreement also provides that each of the
shareholder parties thereto, including HMRI, has the right to purchase its
Pro Rata Share (as defined therein) of equity securities offered by the
Issuer, upon the same terms as other persons to whom such equity securities
are offered, subject to exclusions for shares issued pursuant to exercises
of stock options, currently exercisable warrants and conversion rights, and
in certain other events or transactions.   

     The description of the Investor Rights Agreement is qualified in its
entirety by reference to such agreement, a copy of which is set forth as
Exhibit 99.C hereto.

ITEM 7.   MATERIAL TO BE FILED AS EXHIBITS.
- -------   ---------------------------------

     Exhibit 99.A   Series D Convertible Preferred Stock Purchase Agreement
                    dated October 2, 1995, by and between HMRI and the
                    Issuer.

     Exhibit 99.B   Technology Development and Services Agreement dated
                    October 2, 1995, by and among HMRI, Hoechst AG, and the
                    Issuer.

     Exhibit 99.C   Amended and Restated Investor Rights Agreement dated as
                    of November 1, 1995, by and among the Issuer, HMRI, and
                    the purchasers of the Issuer's Series B Convertible
                    Preferred Stock and Series C Convertible Preferred
                    Stock

     Exhibit 99.D   Agreement to File Jointly dated March 21, 1996, by and
                    between HMRI and HCorp.

     Exhibit 99.E   Information concerning directors and officers of HMRI.

     Exhibit 99.F   Information concerning directors and executive officers
                    of HCorp and Hoechst AG.


<PAGE>                                                                8
                                   SIGNATURE

     After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete
and correct.

                                        HOECHST MARION ROUSSEL, INC.



Date: March 21, 1996                    By:  /s/ William K. Hoskins
                                             William K. Hoskins
                                             Vice President, 
                                             General Counsel, and 
                                             Corporate Secretary












































<PAGE>                                                                9
                                   SIGNATURE

     After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete
and correct.

                                        HOECHST CORPORATION



Date:  March 21, 1996                   By:  /s/ David A. Jenkins
                                             David A. Jenkins
                                             Vice President, General
                                             Counsel and Secretary














































<PAGE>                                                                10
                                 EXHIBIT INDEX


Exhibit No.         Description                                  Page No.
- -----------         ------------                                 ---------

   99.A        Series D Convertible Preferred Stock Purchase 
               Agreement dated as of October 2, 1995, by and 
               between HMRI and the Issuer (to be filed by 
               amendment)

   99.B        Technology Development and Services Agreement 
               dated as of October 2, 1995, by and among 
               Hoechst AG, HMRI, and the Issuer (to be filed
               by amendment)

   99.C        Amended and Restated Investor Rights Agreement 
               dated as of November 1, 1995, by and among the 
               Issuer, HMRI, and the purchasers of the Issuer's
               Series B Convertible Preferred Stock and Series
               C Convertible Preferred Stock (to be filed by 
               amendment)
                
   99.D        Agreement to File Jointly by and between HMRI          11
               and HCorp dated March 21, 1996

   99.E        Information concerning directors and officers          12
               of HMRI 

   99.F        Information concerning directors and executive         13
               officers of HCorp and Hoechst AG.





























<PAGE>                                                                11
                                  EXHIBIT 99.D

                           AGREEMENT TO FILE JOINTLY

     We, the undersigned, hereby express our agreement that the attached
Schedule 13D is filed on behalf of each of us.

                                        HOECHST CORPORATION



Date:  March 21, 1996                   By:  /s/ David A Jenkins
                                             David A. Jenkins
                                             Vice President, General
                                             Counsel and Secretary


                                        HOECHST MARION ROUSSEL, INC.



Date:  March 21, 1996                   By:  /s/ William K. Hoskins
                                             Vice President,
                                             General Counsel, and
                                             Corporate Secretary



































<PAGE>                                                                12
                                  Exhibit 99.E

             Directors and Officers of Hoechst Marion Roussel, Inc.

     The following sets forth the name, title, business address, and
present principal occupation of each of the directors and executive
officers of HMRI as of January 1, 1996.  All are citizens of the United
States unless otherwise indicated in parentheses under his or her name.

Name                     Title                    Address
- ----                     -----                    -------

Fred W. Lyons, Jr.       Chairman of the Board    10236 Marion Park Drive
                         and Director             Kansas City, MO  64137

Peter W. Ladell          President and Chief      10236 Marion Park Drive
(Canada)                 Executive Officer        Kansas City, MO  64137
                         and Director

Alban W. Schuele         Vice President, Chief    10236 Marion Park Drive
                         Financial Officer and    Kansas City, MO  64137
                         Treasurer and Director

Richard J. Markham       Deputy Head of the       10236 Marion Park Drive
                         Pharmaceutical Division  Kansas City, MO  64137
                         of Hoechst AG and
                         Director of HMRI

Jean-Pierre Godard       Head of the Pharma-      Hoechst AG
(France)                 ceuticals Division of    65926 Frankfurt Main
                         Hoechst AG and President Germany
                         of the Board of Roussel 
                         Uclaf; Director of HMRI

Karl-Gerhard Seifert,    Member of the Board of   Hoechst AG
Ph.D. (Germany)          Management; Pharmaceuti- 65926 Frankfurt Main
                         cal and Diagnostics      Germany
                         Divisions; Schwarzkopf
                         of Hoechst AG
                         and Director of HMRI

James P. Mitchum         Vice President, Finance  10236 Marion Park Drive
                         and Administration,      Kansas City, MO  64137
                         and Controller

Tommy R. White           Vice President, Human    10236 Marion Park Drive
                         Resources and Corporate  Kansas City, MO  64137
                         Relations

Kirk R. Schueler         Vice President, U. S.    10236 Marion Park Drive
                         Commercial Director      Kansas City, MO  64137

Charles A. Portwood      Vice President,          10236 Marion Park Drive
                         Operations               Kansas City, MO  64137

William K. Hoskins       Vice President,          10236 Marion Park Drive
                         General Counsel and      Kansas City, MO  64137
                         Corporate Secretary


<PAGE>                                                                13
                                  EXHIBIT 99.F

                          CERTAIN INFORMATION RELATING
                      TO DIRECTORS AND EXECUTIVE OFFICERS

     1.   Directors and Executive Officers of Hoechst AG.
          -----------------------------------------------

     The following table sets forth the name, business address, present
principal occupation or employment of each member of the Supervisory Board
and the Board of Management (substantially the same as directors and
executive officers) of Hoechst AG.  All of the members of the Supervisory
Board and the Board of Management are citizens of Germany except for
Messrs. Furgler, Hussain, and Drew who are citizens of Switzerland, Kuwait
and the United States, respectively.  Unless otherwise indicated, the
business address of each of the individuals named below is Hoechst AG,
65926 Frankfurt Main, Germany, and each occupation set forth opposite the
individual's name refers to employment with Hoechst AG.


Name and Business Address     Principal Present Occupation
- -------------------------     ----------------------------
SUPERVISORY BOARD   

Erhard Bouillon               Chairman of the Supervisory Board

Willi Esser                   Mechanic; Member of the Central Works Council
                              of Hoechst AG

Dr. -Ing. E.h.                Member of the Supervisory Board
Werner H. Dieter
Mannesmann AG
Postfach 10 36 41
40027 Dusseldorf
Germany

Dietrich-Kurt Frowein         Member of the Board of Management of 
Commerzbank AG                Commerzbank AG
Postfach 10 05 05
60005 Frankfurt am Main
Germany

Dr. iur. Dr. h.c. mult.       Member of the Supervisory Board
Kurt Furgler
DoufourstraBe 34
Scoitzerland
CH-9000 St. Gallen
Switzerland

Prof. Dr. rer. nat.           Member of the Supervisory Board
Dr. -Ing. E.h.
Heinz Harnisch

Jugen Hilger                  Member of the Central Works Council of
                              Hoechst AG

Dr. rer. nat.                 Graduate Chemist; Chairman of 
Ingolf Hornke                 the Senior Executives' Committee of
                              Hoechst AG

<PAGE>                                                                14
Hani Abdul-Aziz Hussain       Managing Director - Marketing Petrochemical
Kuwait Petroleum Corp.        Industries Co. (K.S.C.), Kuwait
P.O. Box 26565
Safat -- Kuwait

Hermann-Heinz Konrad          Graduate Engineer; Deputy Chairman of the
                              Senior Executives' Committee of Hoechst AG

Rainer Kumlehn                Electrician; Regional Head of the IG Chemie-
IG Chemie-Papier              Papier-Keramik Hessen
Keramik Hessen
Wilhelm-Lerner-StraBe 69-7
60329 Frankfurt am Main
Germany

Prof. Dr. rer. nat.           University of Konstanz; Biology Department
Dr. rer. nat. h.c.
Hubert Markl
HollanderstraBe 22
78465 Konstanz
Germany

Juergen Sarrazin              Chairman of the Board of Managing Directors
Dresdner Bank AG              of Dresdner Bank AG
Jergen-Ponto Platz
D-60301 frankfurt am Main
Germany

Egon Schaefer                 Electrician; Deputy Chairman of IG Chemie-
IG Chemie-Papier-Keramik      Papier-Keramik
Postfach 30
30030 Hannover
Germany

Dr. jur.                      Chairman of the Board of Management of
Hans-Juergen Schinzler        Muenchener Ruckversicherungs-Gesellschaft
Muenchener
Ruckversicherungs-Gesellschaft
80791 Munchen
Germany

Konrad Starnecker             Skilled Chemical Plant Operative; Member of
Furstbert 1                   the Central Works Council of Hoechst AG
84556 Kastl, Kr. Altotting
Germany

Wolfgang Vetter               Fitter; Member of the Central Germany Works
LinkstraBe 1                  Council of Works Council of Hoechst AG
65933 Frankfurt am Main

Kurt F. Viermetz              Vice Chairman of J.P. Morgan & Co. Inc.
J.P. Morgan & Co. Inc.
60 Wall Street
New York, New York
10260-0060




<PAGE>                                                                15
Arnold Weber                  Chairman of the Central Works Council of
Rauenthaler 31                Hoechst AG
60529 Frankfurt am Main
Germany

Adam Wegehingel               Member of the Central Works Council of
Hoechst AG                    Hoechst AG
Werk Gersthofen
Adolph von Baeyer Str. 3
866369 Gersthofen
Germany
     
BOARD OF MANAGEMENT 

Juergen Dormann               Chairman of the Board of Management

Dr. Ernest H. Drew, Ph.D.     Member of the Board of Management; Chemicals,
                              Specialty Chemicals, Technical Polymers
                              Divisions

Prof. Dr. rer. nat.           Member of the Board of Management;
Utz-Hellmuth Felcht           Director of Personnel; Research; Herberts,
                              SGL Carbon, Hoechst CeramTec

Dr. jur. Martin Fruehauf      Member of the Board of Management; Finance
                              and Accounts, Legal Matters, Patents, Taxes,
                              Insurance

Dr. rer. pol.                 Deputy Chairman of the Board of Management;
Guenter Metz                  Fibres and Fibre Intermediates, Plastics and
                              Films Divisions; the Americas

Dipl. -Kfm.                   Member of the Board of Management;
Justus Mische                 Europe, Africa; Materials Management

Dr. rer. nat.                 Member of the Board of Management;
Karl-Gerhard Seifert          Pharmaceutical and Diagnostics Divisions;
                              Schwarzkopf

Dr. -Ing.                     Member of the Board of Management; Messer
Ernst Schadow                 Griesheim, Uhde; Engineering and
                              Environmental Protection; Hoechst Site

Dipl.-Ing.                    Member of the Board of Management; Asia;
Horst Waesche                 AgrEvo; Hoechst Veterinar; Informatics and
                              Communication

     2.   Directors and Executive Officers of Hoechst Corporation. 
          --------------------------------------------------------

     The following table sets forth the name and present principal
occupation or employment of each director and executive officer of Hoechst
Corporation.  All such directors and officers are citizens of the United
States, except Messrs. Engels, Felcht, Fruehauf, Metz, Schmieder, Seifert
and Warning who are citizens of Germany. The business address of Messrs.
Benz, Engels, Kennedy, Harris, Schmieder and Warning is Hoechst Celanese
Corporation ("HCC"), Route 202-206, P.O. Box 2500, Somerville, New Jersey
08876-1258, and the business address of Messrs. Drew, Felcht, Fruehauf,
Metz and Seifert is Hoechst AG, 65926 Frankfurt Main,  Germany.

<PAGE>                                                                16
Name/Position with Parent     Principal Present Occupation
- -------------------------     ----------------------------
Harry R. Benz                 Senior Vice President - Finance,
Senior Vice President -       Chief Financial Officer and Director - HCC
Finance and Chief
Financial Officer
and Director

Dr. Ernest H. Drew, Ph.D.     See "Directors and Executive Officers of
Director                      Hoechst AG"

Prof. Dr. rer. nat. Utz-      See "Directors and Executive Officers of 
Hellmuth Felcht               Hoechst AG"
Director

Dr. jur. Martin Fruehauf      See "Directors and Executive Officers of 
Director                      Hoechst AG"

William B. Harris             Senior Vice President and Director - HCC
Director

David A. Jenkins              Vice President and General Counsel and
Vice President, General       Director - HCC
Counsel and Secretary

Thomas F. Kennedy             President and Chief Executive Officer and
Director                      Director - HCC

Dr. rer. pol.                 See "Directors and Executive Officers of
Guenter Metz                  Hoechst AG"
Chairman of the Board,
Chief Operating Officer
and President

Perry W. Premdas              Vice President and Treasurer - HCC
Vice President and 
Treasurer 

Dr. Klaus J. Schmieder        Vice President - HCC
Vice President

Alban W. Schuele              See "Directors and Officers of Hoechst Marion
Vice President                Roussel, Inc."

Dr. rer. nat. Karl-Gerhard    See "Directors and Executive Officers of
                              Seifert                       Hoechst AG"
Director

Raymond W. Smedley            Vice President and Controller - HCC
Vice President 
and Controller 

Dr. Klaus Warning             Vice President and Director - HCC
Director



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