MERCK & CO INC
11-K, 1995-11-22
PHARMACEUTICAL PREPARATIONS
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                  SECURITIES AND EXCHANGE COMMISSION

                        Washington, D.C. 20549


                              FORM 11-K


              Annual Report Pursuant to Section 15(d) of
                 The Securities Exchange Act of 1934



  (Mark One)
  (X)     ANNUAL REPORT PURSUANT TO SECTION 15(D) OF THE SECURITIES
          EXCHANGE ACT OF 1934.

          For the period* ended        September 30, 1995
                                  or
  (  )    TRANSITION REPORT PURSUANT TO SECTION 15(D) OF THE
          SECURITIES EXCHANGE ACT OF 1934.

          For the transition period from _______  to  _________ 

          Commission File Number 1-3305  (Merck & Co., Inc.)

          A.   Full title of the plan and address of the plan, if
               different from that of the issuer named below:

                           ASTRA MERCK INC.
                  EMPLOYEE SAVINGS AND SECRUITY PLAN
                      725 Chesterbrook Boulevard
                        Wayne, PA  19087-5677

          B.   Name of issuer of the securities held pursuant to
               the plan and the address of its principal executive
               office:

                          MERCK & CO., INC.
                           One Merck Drive
                 Whitehouse Station,  NJ  08889-0100


  * This report is being filed pursuant to General Instruction
  A(2)(ii) of Form S-8.














                              1 <PAGE> 
<PAGE>




                  Report of Independent Accountants


        November 3, 1995

        To the Participants and Plan Administrative Committee of the

         Astra Merck Inc. Employee Savings and Security Plan


        In our opinion, the accompanying Statement of Net Assets
        Available for Benefits and the related Statement of Changes
        in Net Assets Available for Benefits, present fairly, in all
        material respects, the net assets available for benefits of
        the Astra Merck Inc. Employee Savings and Security Plan (the
        "Plan") at September 30, 1995, and the changes in net assets
        available for benefits for the nine months then ended, in
        conformity with generally accepted accounting principles.
        These financial statements are the responsibility of the
        Plan's management; our responsibility is to express an
        opinion on these financial statements based on our audit. We
        conducted our audit of these statements in accordance with
        generally accepted auditing standards which require that we
        plan and perform the audit to obtain reasonable assurance
        about whether the financial statements are free of material
        misstatement. An audit includes examining, on a test basis,
        evidence supporting the amounts and disclosures in the
        financial statements, assessing the accounting principles
        used and significant estimates made by management and
        evaluating the overall financial statement presentation. We
        believe that our audit provides a reasonable basis for the
        opinion expressed above.

        Our audit was performed for the purpose of forming an
        opinion on the basic financial statements taken as a whole.
        The additional information included in Schedules I and II is
        presented for purposes of additional analysis and is not a
        required part of the basic financial statements but is
        additional information required by ERISA. The Fund
        Information in the Statement of Net Assets Available for
        Benefits, and the Statement of Changes in Net Assets
        Available for Benefits, is presented for purposes of
        additional analysis, rather than to present the net assets
        available for plan benefits and changes in net assets
        available for plan benefits of each fund. Schedules I and II
        and the Fund Information have been subjected to the auditing
        procedures applied in the audit of the basic financial
        statements and, in our opinion, are fairly stated in all
        material respects in relation to the basic financial
        statements taken as a whole.




        Price Waterhouse LLP




                                 2 <PAGE> 
<PAGE>
<TABLE>
Astra Merck Inc. Employee Savings and Security Plan
Statement of Net Assets Available for Benefits, with Fund Information
September 30, 1995
<CAPTION>


                                     Merck Common     Fidelity Magellan   Fidelity Equity-     Fidelity Growth   Fidelity Growth &
                                      Stock*              Fund*            Income Fund         Company Fund      Income Portfolio

<S>                                  <C>                <C>                 <C>                 <C>                 <C>

Assets:
Investments at fair value:
   Common stock                      $21,593,603
   Mutual funds                                           $4,949,782            $542,385          $1,233,861         $1,321,464
   Participant loans 
- - -------------------------------------------------------------------------------------------------------------------------------
                                      21,593,603          $4,949,782            $542,385           1,233,861          1,321,464

Receivables:
   Participant contributions             121,193              70,913              10,361              28,183             34,073
   Employer contributions                 31,626              18,600               2,605               7,327              8,774
   Accrued Interest and Dividends        133,273               1,668                 230                 334                266
- - -------------------------------------------------------------------------------------------------------------------------------
Net assets available for benefits    $21,879,695          $5,040,963            $555,581           1,269,705         $1,364,577











</TABLE> 
                                               3 <PAGE> 
<PAGE>
<TABLE>
Astra Merck Inc. Employee Savings and Security Plan
Statement of Net Assets Available for Benefits, with Fund Information
September 30, 1995
Continued
<CAPTION>


                                    Fidelity Intermediate      Fidelity Retirement       Fidelity OTC          Fidelity 
                                      Bond Fund                 Growth Fund               Portfolio          Overseas Fund

<S>                                  <C>                             <C>                    <C>              <C>

Assets:
Investments at fair value:
   Common stock
   Mutual funds                      $214,106                        $396,339               $629,105         $688,799
   Participant loans 		   
- - ---------------------------------------------------------------------------------------------------------------------
                                      214,106                         396,339                629,105          688,799

Receivables:
   Participant contributions           6,119                           12,393                 16,071           19,161
   Employer contributions              2,033                            3,089                  3,999            4,479
   Accrued Interest and Dividends          5                               85                    242              275
- - ---------------------------------------------------------------------------------------------------------------------
Net assets available for benefits   $222,263                         $411,906               $649,417         $712,714


















</TABLE> 
                                                             4 <PAGE> 
<PAGE>
<TABLE>
Astra Merck Inc. Employee Savings and Security Plan
Statement of Net Assets Available for Benefits, with Fund Information
September 30, 1995
Continued
<CAPTION>

                                                                        Fidelity        Fidelity
				                    Fidelity           Retirement       U.S. Equity   Participant
                              Fidelity Balanced   Retirement Money     Govt. Money      Index           Loan         
                                    Fund          Market Portfolio   Market Portfolio   Portfolio       Fund	     Total
<S>                                <C>                <C>            <C>               <C>              <C>          <C>

Assets:
Investments at fair value:
   Common stock                                                                                                      $21,593,603
   Mutual funds                    $1,280,756         $403,502       $397,898          $293,534                       12,351,531
   Participant loans                                                                                    $1,218,350     1,218,350
- - --------------------------------------------------------------------------------------------------------------------------------
                                    1,280,756          403,502        397,898           293,534         $1,218,350    35,163,484

Receivables:
   Participant contributions           19,574            5,475           2,292             9,357                         355,165
   Employer contributions               5,380            1,554             736             2,494                          92,696
   Accrued Interest and Dividends         390              103              82                76                         137,029
- - --------------------------------------------------------------------------------------------------------------------------------
Net assets available for benefits  $1,306,100         $410,634        $401,008          $305,461         $1,218,350  $35,748,374






<FN>

* Represents 5% or more of the Plan investments as of September 30, 1995.
The accompanying notes are an integral part of these financial statements.
</TABLE>
					  5 <PAGE>
<PAGE>
<TABLE>
Astra Merck Inc. Employee Savings and Security Plan
Statement of Changes in Net Assets Available for Benefits, with Fund Information
For the Nine Months Ended September 30, 1995
<CAPTION>

                                         Merck Common   Fidelity    Fidelity   Fidelity    Fidelity
                                            Stock       Magellan    Equity-    Growth       Growth &
                                                        Fund        Income     Company      Income
                                                                     Fund        Fund       Portfolio
<S>                                      <C>            <C>           <C>        <C>          <C>


Additions to net assets attributed to:

 Investment income:
   Net appreciation in fair value of
     investments                         $10,372,353    $1,284,077     $63,850   $262,059      $188,172
     Dividends                               350,023        15,814      10,528                   42,132
     Interest                                 40,293        13,232       1,761      2,333         2,094
- - -------------------------------------------------------------------------------------------------------
       Total income on investments        10,762,669     1,313,123      76,139    264,392       232,398
- - -------------------------------------------------------------------------------------------------------

Contributions to the Plan:
   Participant contributions               1,066,485       608,734      90,108    224,929       273,647
   Employer contributions                    279,599       158,299      21,985     58,252        71,628
   Rollovers from other qualified plans       65,090        65,492      13,870     38,990        76,377
- - -------------------------------------------------------------------------------------------------------
      Total contributions                  1,411,174       832,525     125,963    322,171       421,652
- - -------------------------------------------------------------------------------------------------------            
      Total additions                     12,173,843     2,145,648     202,102    586,563       654,050
- - ------------------------------------------------------------------------------------------------------

Deductions from net assets attributed to:
   Withdrawls                               (182,795)       (8,893)                  (637)       (2,404)
- - --------------------------------------------------------------------------------------------------------
   Transfers among funds:
    Net reallocations                       (555,390)      149,192     123,349    143,567        (3,188)
    Loans to participants, principal        (251,533)      (74,820)    (19,235)   (22,453)       (9,825)
    Loan principal repayments from
     participants                             110,301        35,998       5,252     16,623       16,141
- - -------------------------------------------------------------------------------------------------------
       Net transfers among funds             (696,622)      110,370     109,366    137,737        3,128
- - -------------------------------------------------------------------------------------------------------
       Total deductions and net
       transfers among funds                 (879,417)      101,477     109,366    137,100          724
- - --------------------------------------------------------------------------------------------------------

       Net increase                         11,294,426     2,247,125     311,468    723,663      654,774

Transfers from Merck                        10,585,269     2,793,838     244,113    546,042      709,803

Net assets available for benefits:

   Beginning of year
- - --------------------------------------------------------------------------------------------------------
   End of year                             $21,879,695    $5,040,963    $555,581 $1,269,705   $1,364,577
</TABLE>
                                                        6 <PAGE> 
<PAGE>
<TABLE>
Astra Merck Inc. Employee Savings and Security Plan
Statement of Changes in Net Assets Available for Benefits, with Fund Information
For the Nine Months Ended September 30, 1995   
Continued
<CAPTION>

                                                Fidelity      Fidelity        Fidelity        Fidelity       Fidelity
                                                Intermediate  Retirement      OTC             Overseas       Balanced
                                                Bond Fund     Growth Fund     Portfolio       Fund           Fund
<S>                                             <C>             <C>            <C>            <C>             <C>
Additions to net assets attributed to:

  Investment income:
   Net appreciation in fair value of 
   investments                                      $680         $33,623       $121,293         $31,895           $64,500
   Dividends                                       8,868                         11,979                            34,764
   Interest                                           62             622          1,442           2,262             3,423
- - -------------------------------------------------------------------------------------------------------------------------
      Total income on investments                  9,610          34,245        134,714          34,157           102,687
- - -------------------------------------------------------------------------------------------------------------------------
 Contributions to the Plan:
   Participant contributions                      83,920          94,779        127,733         176,604           182,968
   Employer contributions                         23,655          22,886         32,035          39,898            50,327
   Rollovers from other qualified plans           11,522          37,356          8,928          36,379            12,170
- - -------------------------------------------------------------------------------------------------------------------------
      Total contributions                        119,097         155,021        168,696         252,881           245,465
- - -------------------------------------------------------------------------------------------------------------------------
      Total additions                            128,707         189,266        303,410         287,038           348,152
- - -------------------------------------------------------------------------------------------------------------------------

Deductions from net assets attributed to:
   Withdrawls                                     (5,881)                        (6,020)            (74)          (51,824)
- - -------------------------------------------------------------------------------------------------------------------------
   Transfers among funds:
    Net reallocations                            (84,410)          9,328         66,114          40,718           113,485
    Loans to participants, principal                              (9,453)       (19,754)        (12,163)          (27,030)
    Loan principal repayments from 
      participants                                   440           2,952          4,792           6,857            16,699
- - -------------------------------------------------------------------------------------------------------------------------
      Net transfers among funds                  (83,970)          2,827         51,152          35,412           103,154
- - -------------------------------------------------------------------------------------------------------------------------
     Total deductions and net transfers 
       among funds                               (89,851)          2,827         45,132          35,338            51,330
- - -------------------------------------------------------------------------------------------------------------------------
      Net increase                                38,856         192,093        348,542         322,376           399,482
Transfers from Merck                             183,407         219,813        300,875         390,338           906,618

Net assets available for benefits:
     Beginning of year
- - -------------------------------------------------------------------------------------------------------------------------
     End of year                                $222,263        $411,906       $649,417        $712,714        $1,306,100
</TABLE>
                                     7 <PAGE> 
<PAGE>
<TABLE>
Astra Merck Inc. Employee Savings and Security Plan
Statement of Changes in Net Assets Available for Benefits, with Fund Information
For the Nine Months Ended September 30, 1995
<CAPTION>

                                            Fidelity         Fidelity            Fidelity      
                                            Retirement       Retirement          U.S. Equity   Participant
                                            Money Market     Gov't. Money        Index         Loan
                                            Portfolio        Market Portfolio    Portfolio     Fund		  Total

<S>                                         <C>              <C>                 <C>          <C>             <C>
Additions to net assets attributed to:

Investment income:
  Net appreciation in fair value of 
       investments                                                               $55,455                         $12,477,957
       Dividends                              $ 16,289           $12,524           3,717                             506,638
       Interest                                    925               771             509                              69,729
- - ----------------------------------------------------------------------------------------------------------------------------
     Total income on investments                17,214            13,295          59,681                          13,054,324
- - ----------------------------------------------------------------------------------------------------------------------------

Contributions to the Plan:
  Participant contributions                     66,916            34,541          79,310                           3,110,674
  Employer contributions                        17,649            10,435          20,904                             807,552
  Rollovers from other qualified plans          13,873             5,805           1,275                             387,127
- - ----------------------------------------------------------------------------------------------------------------------------
     Total contributions                        98,438            50,781         101,489                           4,305,353
- - ----------------------------------------------------------------------------------------------------------------------------
     Total additions                           115,652            64,076         161,170                          17,359,677
- - ----------------------------------------------------------------------------------------------------------------------------

Deductions from net assets attributed to:

  Withdrawls                                   (28,320)             (879)           (152)                           (287,879)
- - ----------------------------------------------------------------------------------------------------------------------------
  Transfers among funds:		     
   Net reallocations                           (44,523)           37,861           3,897
   Loans to participants, principal             (3,027)           (2,123)         (4,384)       $455,800
   Loan principal repayments from 
    participants                                 3,473             2,369           7,616        (229,513)     
- - ----------------------------------------------------------------------------------------------------------------------------
     Net transfers among funds                 (44,077)           38,107           7,129         226,287
- - ----------------------------------------------------------------------------------------------------------------------------
     Total deductions and net transfers 
      among funds                              (72,397)           37,228           6,977         226,287             (287,879)
- - -----------------------------------------------------------------------------------------------------------------------------
     Net increase                               43,255           101,304         168,147         226,287           17,071,798

Transfers from Merck                           367,379           299,704         137,314         992,063           18,676,576

Net assets available for benefits:

     Beginning of year
- - ----------------------------------------------------------------------------------------------------------------------------
     End of year                             $410,634          $401,008        $305,461      $1,218,350          $35,748,374

<FN>
The accompanying notes are an integral part of these financial statements.
</TABLE>     
                                8 <PAGE> 
<PAGE>
Astra Merck Inc. Employee Savings and Security Plan
Notes to Financial Statements
September 30, 1995

        1.  Description of the Plan

            The Astra Merck Inc. (the "Company") Employee Savings
            and Security Plan (the "Plan"), established January 1,
            1995, was designed to provide employees a systematic
            means of saving and investing for the future. Regular
            full-time, part-time, and temporary employees of the
            Company as defined by the Plan, who have completed at
            least one year of employment are eligible to
            participate in the Plan on the next enrollment date
            (the first day of each January and each July).

            The Plan is administered by the Plan Administrative
            Committee. All costs of administering the Plan are
            borne by the Company.

            Contributions.  Participants may contribute from 2% to
            15% of their base pay and can designate contributions
            as pre-tax, after-tax or a combination of both. The
            Company matches 50% of employee contributions up to 5%
            of base pay per pay period. Company matching
            contributions are invested in the same investments that
            participants designate for their own contributions.
            Both employee and employer contributions to the Plan
            are limited to maximum amounts established under the
            Internal Revenue Code.

            In addition, participants may transfer assets that are
            held for their benefit by former employers (rollover
            contributions) into the Plan. 

            Investment Options.  Participants direct the investment
            of their contributions into any of the following
            investment options, including Merck & Co., Inc.
            ("Merck") Common Stock: 

              Merck Common Stock
              This portfolio consists of shares of Merck Common
              Stock.

              Fidelity Magellan Fund
              The Magellan Fund invests primarily in common stock
              and securities convertible to common stock issued by
              companies operating in the U.S. and/or abroad as well
              as foreign companies. The fund seeks investment
              growth by making a profit on invested capital over
              the long term.

              Fidelity Equity-Income Fund
              The Equity-Income Fund invests in income-producing
              equity securities and seeks a dividend yield that
              exceeds the composite yield of the S&P 500 Index; at
              the same time, it considers the potential for capital
              growth.





                             9  <PAGE> 
<PAGE>
Astra Merck Inc. Employee Savings and Security Plan
Notes to Financial Statements
September 30, 1995

              Fidelity Growth Company Fund
              The Growth Company Fund seeks capital appreciation
              mainly through investment in common stocks and
              securities convertible into common stocks with an
              emphasis on capital gains rather than on dividend
              income.

              Fidelity Growth & Income Portfolio
              The Growth & Income Portfolio seeks a combination of
              capital growth and current income consistent with
              reasonable investment risk. It seeks securities of 
              companies with potential for earnings growth while
              paying current dividends. 

              Fidelity Intermediate Bond Fund
              The Intermediate Bond Fund invests in domestic and
              foreign investment-grade securities with intermediate
              maturities. The dollar-weighted average maturity of
              its obligations ranges between three and ten years.

              Fidelity Retirement Growth Fund
              The Retirement Growth Fund seeks capital appreciation
              by investing primarily in common stocks issued by
              companies operating in the U.S. and/or abroad.
              Investments are diversified among a variety of
              industries and sectors within the market.

              Fidelity OTC Portfolio
              The OTC Portfolio seeks capital appreciation through
              investment in securities that are traded in the over-
              the-counter ("OTC") securities market. Though this
              portfolio invests mainly in common stocks, it can
              also invest in preferred stocks and debt obligations
              as well as all other securities offered by the OTC
              market.

              Fidelity Overseas Fund
              The Overseas Fund seeks capital appreciation,
              primarily through investments in foreign securities.
              Normally, at least 65% of its total assets are
              invested in securities of companies from at least
              three countries outside of North America (generally
              these countries are located in Central and South
              America, the Far East and Pacific basin, and Western
              Europe).

              Fidelity Balanced Fund
              The emphasis of the Balanced Fund is income with
              investments in both stocks and bonds. At least 25% of
              its total assets will always be invested in fixed-
              income senior securities to primarily preserve
              principal.




                              10 <PAGE> 
<PAGE>
Astra Merck Inc. Employee Savings and Security Plan
Notes to Financial Statements
September 30, 1995

              Fidelity Retirement Money Market Portfolio
              The Money Market Portfolio invests in high quality,
              U.S. dollar-denominated money market instruments of
              U.S. and foreign issuers. Investments include short-
              term corporate obligations, U.S. government
              obligations and certificates of deposit.

              Fidelity Retirement Government Money Market Portfolio
              The Government Money Market Portfolio invests in
              obligations issued or guaranteed as to principal and
              interest by the U.S. Government, its agencies or
              instrumentalities.

              Fidelity U.S. Equity Index Portfolio
              The U.S. Equity Index Portfolio seeks investment
              results that correspond to the total return
              performance of United States' publicly traded stocks.
              Total return performance is the combination of
              capital changes and income. Many investments made by
              this portfolio offer the potential for both dividend
              income and capital appreciation over the long term.

              Participant Loan Fund
              The Loan Fund is comprised of amounts transferred
              from other funds and represents the balance of
              outstanding participant loans.

            Vesting.  Participants are immediately vested in their
            contributions, all Company matching contributions, plus
            actual earnings thereon.

            Participants' Loans.  Participants may borrow from
            their account balances. The minimum loan is $500 and
            the maximum loan is the lesser of $50,000 less the
            highest outstanding loan balance, if any, during the
            one year period prior to the new loan application date,
            or 50% of the participant's account balance less any
            current outstanding loan balance. Participant
            investments are liquidated on a pro rata basis to fund
            the loan. The interest rate is the rate in effect the
            month the loan is valued and is based on the prime rate
            of the Morgan Guaranty Trust Company of New York, plus
            one percent per annum. Activity related to these
            borrowings is reflected in the Participants' Loan
            Account column of the financial statements.

        2.  Summary of Accounting Policies

            The financial statements of the Plan have been prepared
            using the accrual basis of accounting. Investments in
            mutual funds and Merck Common Stock are stated at
            quoted market value. Participant loans are valued at
            cost which approximates fair value. Dividend income is
            recorded on the ex-dividend date. The appreciation in
            market value of investments is based on the beginning
            of the year market value or value at the time of
            purchase during the year and is included in the

                              11 <PAGE> 
<PAGE>
Astra Merck Inc. Employee Savings and Security Plan
Notes to Financial Statements
September 30, 1995

            Statement of Changes in Net Assets Available for
            Benefits.

        3.  Income Tax Status

            The Plan administrator and the Plan's tax counsel
            believe that the Plan is designed and is currently
            being operated in compliance with the applicable
            requirements of the Internal Revenue Code. A request
            for a favorable determination letter will be filed with
            the Internal Revenue Service in conjunction with the
            Company's 1995 tax return filing.

        4.  Party-in-Interest Transactions

            On January 1, 1995, in connection with the transfer of
            assets to the Company on November 1, 1994 to effect a
            joint venture between Astra AB and Merck, certain
            employees of Merck became employees of the Company. In
            accordance with the terms of the agreements governing
            the formation of the joint venture, account balances of
            these employees who were participants in Merck's
            Employee Savings and Security Plan, totalling
            $18,676,576, were transferred to the Plan, effective
            January 1, 1995.































                              12 <PAGE> 
<PAGE>
                                                          Schedule I

<TABLE>
Astra Merck Inc. Employee Savings & Security Plan
Schedule of Assets Held for Investment Purposes
September 30, 1995
<CAPTION> 
                                                                        Market
                                                                        Value                     Cost   
<S>                                                                   <C>                     <C>
Merck Common Stock*                                                    $21,593,603            $14,935,287
Fidelity Magellan Fund*                                                  4,949,782              3,693,322
Fidelity Equity-Income Fund                                                542,385                482,376
Fidelity Growth Company Fund                                             1,233,861                980,127
Fidelity Growth & Income Portfolio                                       1,321,464              1,165,498
Fidelity Intermediate Bond Fund                                            214,106                214,539
Fidelity Retirement Growth Fund                                            396,339                365,013
Fidelity OTC Portfolio                                                     629,105                515,591
Fidelity Overseas Fund                                                     688,799                658,700
Fidelity Balanced Fund                                                   1,280,756              1,219,649
Fidelity Retirement Money Market Portfolio                                 403,502                403,502
Fidelity Retirement Government Money Market Portfolio                      397,898                397,898
Fidelity U.S. Equity Index Portfolio                                       293,534                241,996
Participant Loan Account (with interest rates ranging from
                   7% to 11%)                                            1,218,350              1,218,350
                                                                       -------------------------------------
                          Totals                                       $35,163,484            $26,491,848

<FN>

* Represents 5% or more of the Plan investments as of September 30, 1995.
  This schedule was derived from data certified as complete and accurate by Fidelity Management Trust Company.
</TABLE>





                                                    13 <PAGE> 
<PAGE>
                                                              Schedule ll


<TABLE>
Astra Merck Inc. Employee Savings and Security Plan  
Schedule of Reportable Transactions
Nine Months Ended September 30, 1995
<CAPTION>	
                                                                                    ------------------Sales----------------------
                                              Number of   Number of     Total                         Net
Description                                   Purchases   Sales      Purchases       Proceeds         Cost            Gain
<S>                                          <C>          <C>        <C>              <C>            <C>              <C>
Merck Common Stock                            83           64        $26,879,750      $15,887,494    $11,944,463       $3,943,031
Fidelity Magellan Fund                        81           55          3,861,726          196,020        168,403           27,617
Fidelity Equity-Income Fund                   43           18            530,359           51,823         47,982            3,841
Fidelity Growth Company Fund                  56           26          1,041,739           69,938         61,613            8,325
Fidelity Growth & Income Portfolio            60           29          1,395,077          261,785        229,579           32,206
Fidelity Intermediate Bond Fund               44           17            310,957           97,532         96,419            1,113
Fidelity Retirement Growth Fund               48           21            413,933           51,217         48,920            2,297
Fidelity OTC Portfolio                        54           27            591,525           83,713         75,934            7,779
Fidelity Overseas Fund                        56           32            708,163           51,258         49,462            1,796
Fidelity Balanced Fund                        52           37          1,373,501          157,246        153,852            3,394
Fidelity Retirement Money Market Portfolio    49           28            510,353          106,850        106,850            -    
Fidelity Retirement Government Money Market
       Portfolio                              44           25            440,441           42,542         42,542            -    
Fidelity U.S. Equity Index Portfolio          42           18            278,391           40,312         36,395            3,917

<FN>
    This schedule was derived from data certified as complete and accurate by Fidelity Management Trust Company.
</TABLE>

















                                          14 <PAGE> 
<PAGE>




                              SIGNATURES


  Pursuant to the requirements of the Securities Exchange Act of
  1934, the trustees (or other persons who administer the employee
  benefit plan) have duly caused this annual report to be signed on
  its behalf by the undersigned thereunto duly authorized.




                              ASTRA MERCK INC.
                              EMPLOYEE SAVINGS AND SECURITY PLAN
                              (Name of Plan)



                              By: /s/ Linda E. Robertson
                              LINDA E. ROBERTSON
                              Administrative Committee


  Dated: November 22, 1995
                              11 <PAGE> 
<PAGE>





   













                  Consent of Independent Accountants


          We hereby consent to the incorporation by reference in
          this Registration Statement on Form S-8 of Merck & Co.,
          Inc., of our report dated November 3, 1995 appearing on
          page 2 of the Report of the Astra Merck Inc. Employee
          Savings and Security Plan on Form 11-K for the nine
          months ended September 30, 1995.


  Price Waterhouse LLP


  Philadelphia, PA
  November 16, 1995





























                              1 <PAGE> 


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