MILLIPORE CORP
S-3/A, 1999-11-16
LABORATORY ANALYTICAL INSTRUMENTS
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 As filed with the Securities and Exchange Commission on November 16, 1999
                                             Registration No.    333-80781


                    SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C. 20549
                 ________________________________________

                               PRE-EFFECTIVE
                              AMENDMENT NO. 2
                                    to
                                 FORM S-3
                          Registration Statement
                                   under
                        The Securities Act of 1933
                          _______________________

                           MILLIPORE CORPORATION
          (Exact name of registrant as specified in its charter)

         Massachusetts                      04-2170233
 (State or other jurisdiction            (I.R.S. Employer
      of incorporation or             Identification Number)
         organization)

                               80 Ashby Road
                       Bedford, Massachusetts  01730
                               (781)533-6000
            (Address, including zip code, and telephone number,
           including area code, of principal executive offices)

                            Jeffrey Rudin, Esq.
                    Vice President and General Counsel
                           Millipore Corporation
                               80 Ashby Road
                       Bedford, Massachusetts  01730
                               (781)533-6000
             (Name, address, including zip code, and telephone
            number, including area code, of agent for service)



Approximate date of commencement of proposed sale to the public:  From time
to time after the effectiveness of the Registration Statement.

If  the  only  securities being registered on this form are  being  offered
pursuant  to  dividend  or interest reinvestment plans,  please  check  the
following
box.

If any of the securities being registered on this form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act
of  1933, other than securities offered only in connection with dividend or
interest reinvestment plans, check the following box.

If  this  form is filed to register additional securities for  an  offering
pursuant  to  Rule  462(b)  under  the Securities  Act,  please  check  the
following box and list the Securities Act registration statement under  the
earlier effective registration statement for the same offering.

If  this  form is a post effective amendment filed pursuant to Rule  462(c)
under  the  Securities Act, check the following box and list the Securities
Act  registration  statement number of the earlier  effective  registration
statement for the same offering.

If  delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box:



The  Registrant hereby amends this Registration Statement on such  date  or
dates  as may be necessary to delay its effective date until the Registrant
shall  file  a  further  amendment  which  specifically  states  that  this
Registration Statement shall thereafter become effective in accordance with
Section  8(a)  of  the  Securities Act of 1933 or until  this  Registration
Statement  shall  become effective on such date as the  Commission,  acting
pursuant to said Section 8(a), may determine.

Subject to Completion
Dated November 16, 1999



PROSPECTUS



                           Millipore Corporation
                               Common Stock
                              660,000 Shares

                               ____________


     The stockholders of Millipore Corporation listed on pages 6 and 7  may
offer  and  sell up to 660,000 shares of Millipore common stock  (including
associated common stock purchase rights) under this prospectus.


      BEFORE  PURCHASING  SHARES OF OUR COMMON STOCK YOU  SHOULD  CAREFULLY
REVIEW THE RISK FACTORS SECTION OF THIS PROSPECTUS WHICH BEGINS ON PAGE 3.

     The selling stockholders may offer their shares in public transactions
on the New York Stock Exchange at prevailing market prices or in negotiated
private  transactions  at  negotiated prices.  Millipore  common  stock  is
listed  on the NYSE with the ticker symbol:  "MIL."  On June 10, 1999,  the
closing  price  of  one share of Millipore common stock  on  the  NYSE  was
$34.0625.

Neither the Securities and Exchange Commission nor any state securities
commission has approved or disapproved of these securities or passed upon
the adequacy or accuracy of this prospectus.  Any representation to the
contrary is a criminal offense.
                          ______________________



             The date of this Prospectus is ___________, 1999



The information in this prospectus is not complete and may be changed.  We
may not sell these securities until the registration statement filed with
the Securities and Exchange Commission is effective.  This prospectus is
not an offer to sell these securities and it is not soliciting an offer to
buy these securities in any state where the offer or sale is not permitted.













We  have  not  authorized  any person to provide information  or  make  any
representation  about  this  offering  that  is  not  in  this  prospectus.
Prospective investors should rely only on the information contained in this
prospectus.  This prospectus is not an offer to sell nor is it  seeking  an
offer  to buy these securities in any jurisdiction where the offer or  sale
is  prohibited.  Information in this prospectus is correct only as  of  its
date, regardless of when any later offer or sale occurs.

                        FORWARD LOOKING STATEMENTS

      This  prospectus  contains forward-looking  statements  that  involve
substantial  risks  and  uncertainties.  Our actual  results  could  differ
materially  from  those  expressed in or implied by  these  forward-looking
statements.   Potential risks and uncertainties that  could  affect  future
operating  results include, among other things, the risks and uncertainties
described in the Risk Factors section on page 3 of this prospectus.


                              ABOUT MILLIPORE

     Millipore Corporation develops, makes and sells products that are used
to  analyze, identify,  monitor and purify liquids and gases. Our  products
are  based  on a variety of membrane and other technologies that   separate
materials  through  physical and chemical methods.  Our products  are  used
primarily in biological and environmental laboratory research and  testing,
in pharmaceutical and food and beverage research, manufacturing and quality
control, and in the purification and control of liquids and gases  used  in
the manufacture of semiconductors.  We manufacture our products at a number
of locations throughout the world.

Our  principal  executive offices are located at 80  Ashby  Road,  Bedford,
Massachusetts 01730 and our telephone number is (781)533-6000.






                                    -2-

                               RISK FACTORS

     You should carefully consider the following risk factors before making
any decision to buy our common stock.

Lack of early success with our pharmaceutical customers can shut us out of
future business with those customers.

The  products  we  sell  to  customers in the pharmaceutical  industry  are
incorporated into the manufacturing processes of these customers.   Once  a
customer  chooses  a  particular product for use in  a  drug  manufacturing
process,  it is unlikely that the customer will later switch to a competing
alternative.  Obtaining the regulatory approvals needed for a change in the
manufacturing   process   is  time-consuming,  expensive   and   uncertain.
Accordingly, if we fail to convince a pharmaceutical customer to choose our
products  early  in  its  manufacturing design  phase,  we  may  lose  that
particular business for good.  Because we face vigorous competition in this
market from companies of substantial financial and technical resources,  we
run  the risk that our competitors will win significant early business with
a customer making it difficult for us to recover that opportunity.

Because of our significant level of international sales, a strengthening of
the  U.S. dollar against foreign currencies can have a significant negative
impact on our total revenues, which we report in U.S. dollars.

We  derive  about  60% of our revenues from customers  outside  the  United
States.  Our sales made in countries other than the U.S. are typically made
in  the  local  currencies  of  those  countries.   When  the  U.S.  dollar
strengthens against a foreign currency, sales made in that currency will be
negatively  impacted when reported in U.S. dollars.   This  occurred  in  a
number  of  Asian countries in 1997 and 1998, when the dollar  strengthened
dramatically  against  the local currencies.  We have historically  reduced
the  risk  associated with a strengthening of the U.S. dollar  by  sourcing
product  from  overseas  plants,  actively managing  cross-border  currency
flows,  and  utilizing a variety of financial instruments.   Despite  these
steps,   the  strengthening  of  the  U.S.  dollar,  particularly   against
currencies in which we earn a significant portion of our revenues  such  as
the  euro  and the Japanese yen, will negatively impact our total revenues,
which we report in U.S. dollars.

Our  net  sales  and  results of operations can be  adversely  affected  by
instability of Asian economies, from which we derive a significant  portion
of our revenues.

      Our sales to customers in Asian markets represented about 24% of  our
total  revenues  in  1998.   Asian countries, including  Japan,  Korea  and
Taiwan,  which  account for a large share of our business in  that  region,
experienced weakness in their currency, banking and equity markets in  late
1997  and 1998.  This weakness adversely affected our sales and results  of
operations in Asia during that period.  A recurrence of instability in  the
region could adversely affect future sales and results of operations.

                                    -3-

We use hazardous materials in our operations and could therefore incur
significant environmental compliance and remediation costs.

We  use  common  organic  solvents and other  hazardous  materials  in  our
manufacturing  processes and our research and development activities.   The
use  of  these materials subjects us to federal, state, local  and  foreign
laws  and  regulations  that set standards for  the  use  and  disposal  of
hazardous  materials.   We  have  in the  past  been  named  a  potentially
responsible party under the federal superfund law with respect to  fourteen
treatment, storage or disposal facilities where hazardous materials that we
had  used  in  our  operations  were  sent.   We  have  paid  a  total   of
approximately  $14  million  in settlement of  our  liability  relating  to
thirteen of these sites, almost all of which was paid prior to 1995, and we
believe  that  any  future remaining liabilities relating  to  these  sites
should  not  have a material adverse effect on our financial condition  and
results of operations.  However, future events, such as changes in existing
laws,   regulations   or  enforcement  policies,  or   the   discovery   of
contamination on sites we operate or to which our waste materials have been
sent,  could  result  in significant additional compliance  or  remediation
costs.

Our performance may be affected in part by the cyclicality of the
semiconductor industry, which at times leads to reduced product demand.

      A  substantial  portion  of  our business  depends  upon  the  future
worldwide growth of the semiconductor industry. The semiconductor  industry
is  highly cyclical and historically has experienced periods of oversupply,
resulting  in significantly reduced demand for capital equipment, including
the  products  we  manufacture.  As a result of this cyclicality,  we  have
experienced  significantly  reduced  revenues  during  these   periods   of
oversupply.   For example, in 1997, early in the most recent  semiconductor
industry  slump,  our  microelectronics  business  segment  generated  $264
million  in revenues, or 36% of our total revenues.  In 1998, during  which
the  industry  slump  appears to have bottomed  out,  our  microelectronics
business  segment generated only $180 million in revenues, or  26%  of  our
total  revenues.  The decrease in sales from 1997 to 1998 was  attributable
in  large part to the semiconductor industry slump.  In the future, if  and
when  the  semiconductor  industry cycle turns down  again,  we  may  again
experience reduced revenues.

Our failure to identify and remediate all material year 2000 risks, or
problems among our suppliers or customers, could significantly disrupt our
business.

     We are aware of the Year 2000 issues that will affect certain products
and  systems  that  were  not designed to properly  handle  the  transition
between the twentieth and twenty-first centuries.  We have taken action  to
attempt  to  ensure  that our business operations  will  not  be  adversely
impacted  by  the transition into the Year 2000.  Among the areas  that  we
have   been   addressing   are  our  internal  information   systems,   our
manufacturing  equipment and facilities, our products, and  the  Year  2000
readiness of our key suppliers and financial institutions.  Our incremental
spending  on our Year 2000 readiness program is not expected to be material
because  most Year 2000 readiness costs will be met with amounts  that  are
normally  budgeted  for  procurement and  maintenance  of  our  information
systems  and infrastructure.  However, the redirection of spending  to  the
implementation of our Year 2000 readiness program may delay


                                    -4-
some productivity improvements.  Though we believe we are  appropriately
preparing ourselves for the Year 2000 and minimizing the chances of any
adverse impact to our business operations, Year 2000 issues present a
number of risks and uncertainties that could materially impact our
business, financial condition or results of operations.  These risks and
uncertainties include, among other things:

failure  of  utilities or transportation systems, which could result  in  a
delay  or  inability  to heat our facilities, manufacture  or  deliver  our
products, or communicate with the outside world
competition for personnel skilled in remediation of Year 2000 issues, which
could  result  in  key  employees involved in our  Year  2000  preparations
leaving us for competing positions
failure  of  our  key suppliers and service providers to be  successful  in
addressing all of their software and system problems, which could result in
failures or significant delays in our receiving materials or services  that
are important to the functioning of our operations
failure  of  our  customers  to address all of their  software  and  system
problems,  which  could  result in a reduction, delay  or  cancellation  of
orders and delay in payment for ordered products
failure  to successfully implement parts of our Year 2000 readiness program
or to fully develop a contingency plan covering responses to any unexpected
failures on our part or the parts of our suppliers or customers.


Further  consolidation of the pharmaceutical industry may have  a  negative
impact on our future operating results.

There   has   been  significant  merger  and  acquisition  activity   among
pharmaceutical manufacturers in recent years resulting in fewer and  larger
customers  of  our Biopharmaceutical & Research business segment.   Further
significant consolidation in this industry could have a negative impact  on
our  operating  results.   The new larger customers  would  have  increased
leverage  in their purchase of products and services from us, and we  could
as  a  result  face  reduced sales or downward pricing pressure.   Also,  a
business  combination between two customers could mean a  consolidation  in
the number of manufacturing facilities and a corresponding reduction in the
combined company's demand for our products.

Technology innovations in the market which we serve may reduce the need  of
our traditional customers for separations products.

Microelectronics  and  biopharmaceutical customers  constantly  attempt  to
reduce   their   manufacturing  costs  and  to  improve  product   quality.
Technology  innovations  to which our customers  would  have  access  could
reduce  or eliminate their need for our separations products.  For example,
if  a  new method of semiconductor manufacture that relies less heavily  on
purified chemicals and gases becomes available and cost-effective, sales to
our  microelectronics customers would be negatively impacted as they  shift
to  the new manufacturing method.  Or, if a new membrane technology of  one
of  our competitors is accepted by the pharmaceutical  industry as a market
standard  for  sterilization, sales of our sterilization membrane  products
would be negatively impacted.
                                   - 5 -

We  may  be  prevented from using certain technology in current or  planned
products because of the patent rights of others.

We and our major competitors spend a good deal of time and money developing
and  patenting new and improved products and technologies.  Because of  the
similarities  of  the technologies used by us and our  competitors,  it  is
sometimes   possible  to  inadvertently  utilize  a  particular  technology
previously  patented by a competitor.  If the competitor were unwilling  to
license  the  technology to us, we would be unable to continue selling  the
particular  product.  We have been engaged in a number of patent  disputes,
none  of  which to date has resulted in a material negative impact  on  our
ability  to sell our products.  However, in the future the outcome of  this
type of dispute could prevent us from selling an important product.


                              USE OF PROCEEDS

      All  net proceeds from the sale of the shares of our common stock  in
this offering will go to the stockholders who offer and sell them.  We will
not receive any proceeds from this offering.


                           SELLING STOCKHOLDERS

      The  selling  stockholders acquired their shares of Millipore  common
stock  from  us in exchange for all of the outstanding equity interests  in
Bioprocessing  Corporation Limited, a company that  we  acquired  from  the
selling stockholders in May 1999.  Some of the selling stockholders are now
or  have  during  the  last three years been active in  the  management  of
Bioprocessing  Corporation Limited and its subsidiaries.   We  have  agreed
with  each  of  the selling stockholders that we would use  our  reasonable
efforts  to register their shares.  Registration of these shares  does  not
necessarily  mean that the selling stockholders will offer or sell  all  or
any of the shares.

      Based  on  the information available to us, including information  we
have  received  from the selling stockholders, we believe that  the  shares
listed  below  represent  all of the shares that each  selling  stockholder
currently beneficially owns.  Any or all of these shares may be sold,  from
time  to  time,  by  the selling stockholders pursuant to this  prospectus.
Since  each of the listed stockholders' percentage ownership of our  common
stock  is less than one percent, no percentage is indicated for any selling
stockholders in the table below.

     Selling                        Shares
   Stockholder                      Owned
                                    and Being
                                    Offered

Crown Capital Limited	       		      51,384
Dr. Frank M. Roberts			              26,613
Thomas M. Swan				                   15,149
Kerry F. Napuk				                   11,259
Dr. Kamran Beyzavi			                 7,495
Alta Berkeley Associates Limited    	33,185
Alta Berkeley LP II    			          228,914



                                   - 6 -



Transatlantic                    				90,915
  Capital General Partners `C' Ltd.
Ferraris Group plc                			30,503
Harry W. Childs				                  30,503
Innoven LLC					                     51,834
BTG International Limited		          69,112
Dr. John N.D. Heap			                 4,510
Geoffrey R. Race				                  2,706
Helen C. Wood				                     1,804
David R. Standen			                 	 1,804
Karen Bambury				                     1,330
Jeff Wilson					                        980



                           PLAN OF DISTRIBUTION

      We  are registering the shares on behalf of the selling stockholders.
The  selling  stockholders may offer their shares of our  common  stock  at
various times in one or more of the following types of transactions:

     on the New York Stock Exchange

     in private negotiated transactions, including in settlement of options
transactions and in settlement of short sales of shares of our common stock

      The  selling  stockholders may sell their  shares  at  market  prices
prevailing at the time of sale, at prices related to such prevailing market
prices, or at negotiated prices.

      The selling stockholders may use broker-dealers to sell their shares.
If   this   happens,  broker-dealers  will  either  receive  discounts   or
commissions from the selling stockholders, or they will receive commissions
from purchasers of shares for whom they acted as agents.

     Selling stockholders also may resell all or a portion of the shares in
open  market  transactions in reliance upon Rule 144 under  the  Securities
Act,  provided  they meet the criteria and conform to the  requirements  of
that rule.



                           AVAILABLE INFORMATION

      We  file annual, quarterly and special reports, proxy statements  and
other information with the SEC.  You may read and copy any document we file
with  the SEC at the SEC's Public Reference Room at 450 Fifth Street, N.W.,
Washington, D.C. 20549.  Please call the SEC at 1-800-SEC-0330 for  further
information  on  the  Public Reference Room.   Our  SEC  filings  are  also
available  to  the  public from the SEC's Website at  "http://www.sec.gov."
Our  common  stock  is listed on the NYSE under the symbol  "MIL"  and  the
periodic  reports, proxy statements and other information we file with  the
SEC  may  also be inspected at the offices of the NYSE at 20 Broad  Street,
New York, New York 10005.


                    WHERE YOU CAN FIND MORE INFORMATION

      The SEC allows us to incorporate by reference the information we file
with them, which means that we can disclose important information to you by
referring you to those documents.

                                   - 7 -
The  information incorporated by reference is considered to be part of this
prospectus,  and  the  information that we file later  with  the  SEC  will
automatically  update and supersede this information.   We  incorporate  by
reference the documents listed below:

      (1)   Our  Amended Annual Report on Form 10-K/A for the  fiscal  year
ended December 31, 1998.

      (2)   Our  Quarterly Reports on Form 10-Q for the  quarterly  periods
ended March 31, 1999, June 30, 1999 and September 30, 1999.

      (3)   The  description of our Common Stock set forth in our Form  8-A
Registration  Statement, filed May 13, 1965, and our Amended Annual  Report
on Form 10-K/A for the fiscal year ended December 31, 1998.

      In  addition,  this prospectus incorporates by reference  any  future
filings we will make with the SEC under Sections 13(a), 13(c), 14 or  15(d)
of  the Securities Exchange Act of 1934 from the date of the initial filing
of  the  Registration  Statement that includes this  prospectus  until  the
termination  of  the  offering.  Information in this prospectus  supersedes
related  information  in  the documents listed  above  and  information  in
subsequently  filed documents supersedes related information in  both  this
prospectus and the incorporated documents.

      We  will, upon written or oral request, provide at no cost a copy  of
any  or all of the information that is incorporated by reference.  Requests
should be made to the following address and telephone number:

               Millipore Corporation
               80 Ashby Road
               Bedford, Massachusetts 01730
               Attention:  General Counsel
               (781)533-6000

     This prospectus is part of a registration statement that we have filed
with  the  SEC.  You should rely only on the information or representations
provided  in this prospectus.  We have not authorized nor have any  of  the
selling  stockholders  authorized anyone  to  provide  you  with  different
information.   The selling stockholders are not making an  offer  of  these
securities in any
state where the offer is not permitted.  You should not assume that the
information in this prospectus is accurate as of any date other than the
date on the front of the document.


                         VALIDITY OF COMMON STOCK

     For the purpose of this offering, our General Counsel, Jeffrey Rudin,
Esq., is providing an opinion on the validity of the shares.


                                  EXPERTS

      The  consolidated  financial statements of the  Corporation  and  its
subsidiaries incorporated herein by reference to the Amended Annual  Report
on  Form  10-K/A  for  the  year ended December  31,  1998,  have  been  so
incorporated  in  reliance  on  the report of  PricewaterhouseCoopers  LLP,
independent accountants, given on the authority of said firm as experts  in
auditing and accounting.


                                   - 8 -

                                  PART II

                  INFORMATION NOT REQUIRED IN PROSPECTUS

Item 14.  Other Expenses of Issuance and Distribution.

      The  following statement sets forth the estimated amounts of expenses
to  be borne by the Registrant in connection with the offering described in
this  Registration Statement.  None of the expenses will be  borne  by  the
security holders.

Securities and Exchange Commission
  Registration Fee            $6,272.72

Legal Fees and Expenses       $5,000.00

Accounting Fees and Expenses  $5,000.00

Miscellaneous Expenses        $1,727.28

     Total Expenses          $18,000.00

Item 15.  Indemnification of Directors and Officers.

      Section 67 of Chapter 156B of the Massachusetts General Laws provides
that  indemnification of directors and officers of the  Registrant  may  be
provided  to  the  extent  specified  or  authorized  by  its  articles  of
organization or a by-law provision adopted by the stockholders.

      Under  Section  9  of the By-laws of the Registrant,  the  Registrant
shall,  to  the extent legally permissible, indemnify each of its directors
and  officers  (including persons who serve at its  request  as  directors,
officers  or  trustees  of another organization or  in  any  capacity  with
respect to any employee benefit plan) against all liabilities and expenses,
including  amounts paid in satisfaction of judgments, in compromise  or  as
fines  and  penalties,  and counsel fees, reasonably  incurred  by  him  in
connection  with the defense or disposition of any action,  suit  or  other
proceeding, whether civil or criminal, in which he may be involved or  with
which he may be threatened, while in office or thereafter, by reason of his
being or having been such a director or officer, except with respect to any
matter as to which he shall have been adjudicated in any proceeding not  to
have  acted in good faith in the reasonable belief that his action  was  in
the  best  interests of the Registrant; provided, however, that as  to  any
matter  disposed  of by a compromise payment by such director  or  officer,
pursuant  to a consent decree or otherwise, no indemnification  either  for
said  payment  or  for  any other expenses shall be  provided  unless  such
compromise  shall be approved as in the best interests of  the  Registrant,
after notice that it involves such indemnification:  (a) by a disinterested
majority  of  the  directors then in office; or (b) by a  majority  of  the
disinterested  directors  then  in office, provided  that  there  has  been
obtained  an opinion in writing of independent legal counsel to the  effect
that  such director or officer appears to have acted in good faith  in  the
reasonable  belief  that  his  action was in  the  best  interests  of  the
Registrant; or (c) by the holders of a majority of the outstanding stock at
the  time  entitled  to  vote  for directors, voting  as  a  single  class,
exclusive  of  any  stock  owned  by any interested  director  or  officer.
Expenses,  including counsel fees, reasonably incurred by any  director  or
officer  in connection with the defense or disposition of any such  action,
suit or other proceeding may be paid from time to time by the Registrant in
advance of the final disposition thereof under receipt of an undertaking by
such director or officer to repay the amounts so paid to the Registrant  if
it is ultimately determined that indemnification for such expenses is not

                                   - 9 -


authorized  under  Section  9.   The right of indemnification  provided  by
Section  9  of the By-laws is not to be exclusive and is not to affect  any
other rights to which any director or officer may be entitled.  As used  in
said   Section  9,  the  terms  "director"  and  "officer"  include   their
respective   heirs,  executors  and  administrators,  and  an  "interested"
director or officer is one against whom in such capacity the proceedings in
question  or  another  proceeding on the same or similar  grounds  is  then
pending.   Nothing  contained  in Section 9  shall  affect  any  rights  to
indemnification  to  which  corporate personnel other  than  directors  and
officers may be entitled by contract or otherwise under law.

          The Registrant has also purchased liability insurance policies
covering directors and officers in certain circumstances.

Item 16.  Exhibits

Number  Description of Exhibit      Location

  4.1   Restated Articles of        Incorporated by reference to
        Organization,               Form 10-K Report for the
        as amended                  year ended December 31, 1996

  4.2   By-Laws, as amended         Incorporated by reference to
                                    Form 10-K Report for year
                                    ended December 31, 1990

  4.3   Shareholders Rights         Incorporated by reference to
        Agreement dated as of       Form 8-K Report filed April,
        April 15, 1988, as amended  1998
        and restated April 16,
        1998 between the
        Registrant and The First
        National Bank of Boston

  5.1   Opinion of Jeffrey Rudin,    Previously filed
        Esq., General Counsel of
        the Registrant, regarding
        legality of shares

 23.1   Consent of                   Previously filed
        PricewaterhouseCoopers LLP

 23.2   Consent of Jeffrey Rudin,    Previously filed
        Esq.

 23.3   Consent of	               		 Previously filed
        PricewaterhouseCoopers LLP
        to Pre-Effective Amendment
        No. 1

 23.4   Consent of               			 Filed herewith
        PricewaterhouseCoopers LLP
        to Pre-Effective Amendment
        No. 2

 24.1   Power of Attorney            Previously filed

 24.2   Power of Attorney            Filed herewith


Item 17.  Undertakings.

     The undersigned registrant hereby undertakes:

      (1)   To  file, during any period in which offers or sales are  being
made, a post-effective amendment to this registration statement (other than
as provided in the proviso and instructions

                                   -10-



to Item 512(a) of Regulation S-K) (i) to include any prospectus required by
Section 10(a)(3) of the Securities Act of 1933 (the "Securities Act"); (ii)
to  reflect  in  the  prospectus any facts  or  events  arising  after  the
effective  date  of  the registration statement (or the most  recent  post-
effective  amendment  thereof) which, individually  or  in  the  aggregate,
represent  a  fundamental   change in the  information  set  forth  in  the
registration statement; and (iii) to include any material information  with
respect  to  the  plan  of  distribution not previously  disclosed  in  the
registration  statement or any material change to such information  in  the
registration statement.


      (2)   That,  for the purpose of determining any liability  under  the
Securities Act, each such post-effective amendment shall be deemed to be  a
new  registration statement relating to the securities offered therein, and
the  offering  of such securities at that time shall be deemed  to  be  the
initial bona fide offering thereof.

      (3)   To  remove  from  registration by  means  of  a  post-effective
amendment any of the securities being registered which remain unsold at the
termination of the offering.

      (4)   That,  for  purposes  of determining any  liability  under  the
Securities  Act, each filing of the registrant's annual report pursuant  to
Section 13(a) or Section 15(d) of the Exchange Act that is incorporated  by
reference  in  the  registration statement shall be  deemed  to  be  a  new
registration statement relating to the securities offered therein, and  the
offering  of  such securities at that time shall be deemed  to  be  in  the
initial bona fide offering thereof.

       Insofar  as  indemnification  for  liabilities  arising  under   the
Securities  Act  may  be permitted to directors, officers  and  controlling
persons  of the registrant pursuant to the provisions described in Item  15
above, or otherwise, the registrant has been advised that in the opinion of
the  Securities  and Exchange Commission, such indemnification  is  against
public  policy  as  expressed  in the Securities  Act  and  is,  therefore,
unenforceable.  In the event that a claim for indemnification against  such
liabilities (other than the payment by the registrant of expenses  incurred
or  paid by a director, officer or controlling person of the registrant  in
the  successful defense of any action, suit or proceeding) is  asserted  by
such  officer,  director  or  controlling person  in  connection  with  the
securities being registered, the registrant will, unless in the opinion  of
its counsel the matter has been settled by controlling precedent, submit to
a   court   of   appropriate  jurisdiction  the   question   whether   such
indemnification  by  it  is  against public  policy  as  expressed  in  the
Securities  Act  and  will be governed by the final  adjudication  of  such
issue.


                                  - 11 -



                                SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it
meets all of the requirements for filing on Form S-3 and has duly caused
this  Pre-Effective Amendment No. 2 to Registration Statement on Form S-3
to be signed on behalf by the undersigned, thereunto duly authorized, in
Bedford, Massachusetts, on November 16, 1999.

     MILLIPORE CORPORATION

     By:  /s/ Jeffrey Rudin
          Jeffrey Rudin
          Vice President

     Date:  November 16, 1999

     Pursuant to the requirements of the Securities Act of 1933, this  Pre-
Effective  Amendment No. 2 to Registration Statement on Form S-3  has  been
signed  below by the following persons in the indicated capacities  and  on
the indicated date.

/s/ C. William Zadel       Chairman, President,  November 16, 1999
C. William Zadel           Chief Executive
                           Officer
                           and Director

/s/ Francis J. Lunger      Vice President,       November 16, 1999
Francis J. Lunger	         Chief Financial Officer

/s/ Kathleen B. Allen      Corporate Controller  November 16, 1999
Kathleen B. Allen

/s/ Robert C. Bishop*      Director              November 16, 1999
Robert C. Bishop

/s/ Samuel C. Butler*      Director              November 16, 1999
Samuel C. Butler

/s/ Robert E. Caldwell*    Director              November 16, 1999
Robert E. Caldwell

/s/ Elaine L. Chao*        Director              November 16, 1999
Elaine L. Chao

/s/ Maureen A. Hendricks*  Director              November 16, 1999
Maureen A. Hendricks

/s/ Mark Hoffman*          Director              November 16, 1999
Mark Hoffman

/s/  Richard J. Lane*      Director              November 16, 1999
Richard J. Lane

/s/ Thomas O. Pyle*        Director              November 16, 1999
Thomas O. Pyle

/s/ John F. Reno*          Director              November 16, 1999
John F. Reno

                                 - 12 -




*The  undersigned, by signing his name hereto, does hereby sign and execute
this Pre-Effective Amendment No. 2 to Registration Statement on Form S-3 on
behalf of the above named directors of Millipore pursuant to the Powers  of
Attorney  executed  by  such  directors  and  previously  filed  with   the
Securities and Exchange Commission or filed herewith.



               *By:_/s/ Jeffrey Rudin__
                    Jeffrey Rudin
                    Attorney in Fact



                                  - 13 -





                               EXHIBIT INDEX


Number         Title of Exhibit

23.4      Consent of Independent Accountants
24.2           Power of Attorney



                                  - 14 -




                               EXHIBIT 23.4

                    CONSENT OF INDEPENDENT ACCOUNTANTS

      We  hereby  consent to the incorporation by reference  in  this  Pre-
Effective  Amendment No. 2 to the Registration Statement on Form  S-3  (No.
333-80781)  of our report, dated January 20, 1999, except for Note  B,  for
which the date is November 12, 1999, relating to the consolidated financial
statements, which appears in Millipore Corporation's Amended Annual  Report
on  Form 10-K/A  for the year ended December 31, 1998.  We also consent  to
the  reference  to  us  under the heading "Experts" in  such  Pre-Effective
Amendment No. 2.


                                   PRICEWATERHOUSECOOPERS LLP



Boston, Massachusetts
November 16, 1999

                                  - 15 -





                               EXHIBIT 24.2

                             POWER OF ATTORNEY




KNOW  ALL MEN BY THESE PRESENTS, that the undersigned Richard J.  Lane,   a
Director   of  Millipore  Corporation  (the  "Corporation"),  does   hereby
constitute  and  appoint C. William Zadel, Francis J.  Lunger  and  Jeffrey
Rudin,  and  each  of them individually, his true and lawful  attorney  and
agent to execute on behalf of the Corporation Pre-effective Amendment No. 2
to  the  Registration Statement on Form S-3 (S.E.C. Registration  No.  333-
80781) relating to 660,000 shares of the Corporation's Common Stock  to  be
offered   and  sold  by  the  former  shareholders  and  optionholders   of
Bioprocessing Corporation Limited, any and all further amendments  to  such
Registration  Statement (including post-effective amendments thereto),  and
any  and  all  such  additional  instruments  related  thereto  which  such
attorneys  and agents may deem to be necessary and desirable to enable  the
Corporation to comply with the requirements of the Securities Act of  1933,
as  amended,  and  any  regulations, orders, or other requirements  of  the
United  States Securities and Exchange Commission thereunder, in connection
with  the preparation and filing of such Pre-effective Amendment No. 2  and
any such further amendments, including specifically, but without limitation
of  the  foregoing, power and authority to sign the name of the undersigned
Director  on  his  behalf,  as such Director,  on  any  such  documents  or
instruments; and the undersigned hereby ratifies and confirms all that such
attorneys and agents shall do or cause to be done by virtue thereof.


SIGNATURE                TITLE                    DATE



/s/ Richard J. Lane_____      Director            October 6, 1999
Richard J. Lane

                                   -16-




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