DIAGNOSTIC PRODUCTS CORP
SC 13G/A, 2000-02-01
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>   1

                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, D.C 20549


                                SCHEDULE 13G/A-8


                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                               (AMENDMENT NO. 8)*



                         DIAGNOSTIC PRODUCTS CORPORATION
- -------------------------------------------------------------------------------
                                (Name of Issuer)



                           COMMON STOCK, NO PAR VALUE
- -------------------------------------------------------------------------------
                         (Title of Class of Securities)



                                   252450-10-1
- -------------------------------------------------------------------------------
                                 (CUSIP Number)



                                DECEMBER 31, 1999
- -------------------------------------------------------------------------------
              (Date of Event which Requires Filing This Statement)


         Check the appropriate box to designate the rule pursuant to which this
Schedule is filed.

         [ ]        Rule 13d-1(b)
         [ ]        Rule 13d-1(c)
         [x]        Rule 13d-1(d)


*The remainder of this cover page shall be filed out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).







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CUSIP NO. 252450-10-1                  13G



1.       NAME OF REPORTING PERSON
         S.S OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

                  LOUIS COLEN


2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP.
                                                                  (A) [ ]
                                                                  (B) [ ]

3.       SEC USE ONLY



4.       CITIZENSHIP OR PLACE OF ORGANIZATION

                  U.S.A.


   NUMBER OF              5.       SOLE VOTING POWER:                 845,800
    SHARES
 BENEFICIALLY             6.       SHARED VOTING POWER:               -0-
   OWNED BY
EACH REPORTING            7.       SOLE DISPOSITIVE POWER:            845,800
  PERSON WITH
                          8.       SHARED DISPOSITIVE POWER:          -0-


9.       AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  845,800


10.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                       [ ]


11.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  6.2%

12.      TYPE OF REPORTING PERSON

                  IN





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Item 1(a)          Name of Issuer:  Diagnostic Products Corporation

Item 1(b)          Address of Issuer's Principal Executive Offices:
                   5700 West 96th Street
                   Los Angeles, California 90045

Item 2(a)          Name of Person Filing:  Louis Colen

Item 2(b)          Address of Principal Office:  2727 Krim Drive
                                                 Los Angeles, CA 90064
Item 2(c)          Citizenship:  U.S.A.

Item 2(d)          Title of Class of Securities:  Common Stock

Item 2(e)          CUSIP Number:  252450-10-1

Item 3             Statement filed Pursuant to Rules 13d-1(b) or
                   13(d)-2(b) or (c):  Not Applicable

Item 4(a)          Amount Beneficially Owned:   845,800 shares

Item 4(b)          Percent of Class:  6.2%

Item 4(c)          Number of shares as to which reporting person has:
                     (i)   sole power to vote or to direct the vote: 845,800
                    (ii)   shared power to vote or to direct the vote: 0
                   (iii)   sole power to dispose or to direct the disposition
                           of: 845,800
                    (iv)   shared power to dispose or to direct the disposition
                           of: 0

Item 5             Ownership of 5% or Less of Class:  Not Applicable

Item 6             Ownership of More than 5% on Behalf of Another
                   Person:  Not Applicable

Item 7             Identification and Classification of the Subsidiary which
                   Acquired the Security Being Reported on by the Parent
                   Holding Company:  Not Applicable

Item 8             Identification and Classification of Members of the
                   Group:  Not Applicable

Item 9             Notice of Dissolution of Group:  Not Applicable

Item 10            Certification:  Not Applicable

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.



Dated:  February 1, 2000                        /s/ Louis Colen
                                                -------------------
                                                    Louis Colen




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