AQUILA BIOPHARMACEUTICALS INC
DEFA14A, 2000-10-20
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                            SCHEDULE 14A INFORMATION

                  Proxy Statement Pursuant to Section 14(a) of
              the Securities Exchange Act of 1934 (Amendment No. )

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Filed by a Party other than the Registrant |_|

Check the appropriate box:

|_|   Preliminary Proxy Statement
|_|   Confidential, for Use of the Commission Only
      (as permitted by Rule 14a-6(e)(2)
|_|   Definitive Proxy Statement
|X|   Definitive Additional Materials
|_|   Soliciting Material Pursuant to ss.240.14a-11(c) or ss.240.14a-12

                         Aquila Biopharmaceuticals, Inc.
________________________________________________________________________________
                (Name of Registrant as Specified In Its Charter)


________________________________________________________________________________
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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<PAGE>

                                                      October 20, 2000

Dear Fellow Stockholder:

We have previously sent to you proxy material for the special meeting of common
stockholders of Aquila Biopharmaceuticals, Inc. to be held on November 15, 2000.
At the meeting, we will ask you to vote on a proposal to adopt a merger
agreement with Antigenics Inc. Your board of directors unanimously recommends
that you vote "FOR" the adoption of the merger agreement.

To approve the merger, a majority of the outstanding shares of Aquila stock must
affirmatively vote for adoption of the merger agreement. If you fail to vote, or
abstain from voting, it will have the same effect as a vote against the merger.

Your vote is very important, no matter how many or how few shares you may own.
If you have not yet voted, please vote TODAY by telephone, by Internet, or by
signing and returning the enclosed voting form in the postage-paid envelope
provided.

Thank you for your support.

Sincerely,


Alison Taunton-Rigby, Ph.D.
President and Chief Executive Officer

================================================================================

                                 IMPORTANT NOTE:

            Remember, you may vote by telephone or Internet -- Simply
            follow the easy instructions on the enclosed voting form.

          If you have any questions, or need assistance in voting your
                    shares, please call our proxy solicitor:

                           INNISFREE M&A INCORPORATED
                           TOLL-FREE at 1-888-750-5834

================================================================================


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