AQUILA BIOPHARMACEUTICALS INC
DEFA14A, 2000-10-31
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                            SCHEDULE 14A INFORMATION

                  Proxy Statement Pursuant to Section 14(a) of
              the Securities Exchange Act of 1934 (Amendment No. )

Filed by the Registrant |_|
Filed by a Party other than the Registrant |_|

Check the appropriate box:

|_|   Preliminary Proxy Statement
|_|   Confidential, for Use of the Commission Only
      (as permitted by Rule 14a-6(e)(2)
|_|   Definitive Proxy Statement
|X|   Definitive Additional Materials
|_|   Soliciting Material Pursuant to ss.240.14a-11(c) or ss.240.14a-12

                        Aquila Biopharmaceuticals, Inc.
________________________________________________________________________________
                (Name of Registrant as Specified In Its Charter)


________________________________________________________________________________
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

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|_|   Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

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      3.    Per unit price or other underlying value of transaction computed
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            the filing fee is calculated and state how it was determined):

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|_|   Fee paid previously with preliminary materials.

|_|   Check box if any part of the fee is offset as provided by Exchange Act
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      4.    Date Filed:

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<PAGE>

AQUILA [LOGO]                                    Aquila Biopharmaceuticals, Inc.

                                                                October 31, 2000

Dear Fellow Stockholder:

According to our latest records, we have not yet received your proxy for the
important special meeting of Aquila Biopharmaceuticals, Inc. to be held on
November 15, 2000, at which your board of directors has unanimously recommended
that shareholders vote in favor of the proposed merger with Antigenics Inc.

Please help your company avoid the expense of further solicitation by signing,
dating and returning the enclosed proxy card today.

Thank you for your cooperation.

Very truly yours,


/s/ Alison Taunton-Rigby

Alison Taunton-Rigby, Ph.D
President and Chief Executive Officer

================================================================================

                       If you have any questions, or need
                        assistance in voting your shares,
                        please call our proxy solicitor,

                           INNISFREE M&A INCORPORATED
                          TOLL-FREE, at 1-888-750-5834.

                                 IMPORTANT NOTE:
                If you hold your shares through a bank or broker,
           you may be able to vote by telephone, or via the Internet.
             Please call Innisfree at 1-888-750-5834 for assistance.

================================================================================



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