<PAGE>
U.S. SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 12B-25 COMMISSION FILE NO.: 0-25098
CUSIP NO.: 30701A106
NOTIFICATION OF LATE FILING
(CHECK ONE):
[ ] FORM 10-K AND FORM 10-KSB [ ] FORM 20-F [ ] FORM 11-K [X] FORM 10-Q AND
FORM 10-QSB [ ] FORM N-SAR FOR PERIOD ENDED: NOVEMBER 30, 2000
[ ] TRANSITION REPORT ON FORM 10-K
[ ] TRANSITION REPORT ON FORM 20-F
[ ] TRANSITION REPORT ON FORM 11-K
[ ] TRANSITION REPORT ON FORM 10-Q
[ ] TRANSITION REPORT ON FORM N-SAR
FOR THE TRANSITION PERIOD ENDED:
--------------------------------------------------------------------------------
READ INSTRUCTION (ON BACK PAGE) BEFORE PREPARING FORM. PLEASE PRINT OR TYPE.
NOTHING IN THIS FORM SHALL BE CONSTRUED TO IMPLY THAT THE COMMISSION HAS
VERIFIED ANY INFORMATION CONTAINED HEREIN.
--------------------------------------------------------------------------------
IF THE NOTIFICATION RELATES TO A PORTION OF THE FILING CHECKED ABOVE, IDENTIFY
THE ITEM(s) TO WHICH THE NOTIFICATION RELATES:
NOT APPLICABLE.
--------------------------------------------------------------------------------
PART I -- REGISTRANT INFORMATION
--------------------------------------------------------------------------------
FULL NAME OF REGISTRANT REPRO-MED SYSTEMS, INC.
-------------------------------
FORMER NAME IF APPLICABLE N/A
-------------------------------
ADDRESS OF PRINCIPAL EXECUTIVE OFFICE
(STREET AND NUMBER) 24 CARPENTER ROAD
-------------------------------
CITY, STATE AND ZIP CODE CHESTER, NY 10918
-------------------------------
--------------------------------------------------------------------------------
<PAGE>
PART II -- RULES 12B-25(B) AND (C)
--------------------------------------------------------------------------------
IF THE SUBJECT REPORT COULD NOT BE FILED WITHOUT UNREASONABLE EFFORT OR EXPENSE
AND THE REGISTRANT SEEKS RELIEF PURSUANT TO RULE 12B-25(B), THE FOLLOWING SHOULD
BE COMPLETED.
[X] (A) THE REASONS DESCRIBED IN REASONABLE DETAIL IN PART III OF THIS FORM
COULD NOT BE ELIMINATED WITHOUT UNREASONABLE EFFORT OR EXPENSE;
[X] (B) THE SUBJECT ANNUAL REPORT, SEMI-ANNUAL REPORT, TRANSITION REPORT ON FORM
10-K, FORM 20-F, 11-K OR FORM N-SAR, OR PORTION THEREOF WILL BE FILED ON OR
BEFORE THE FIFTEENTH CALENDAR DAY FOLLOWING THE PRESCRIBED DUE DATE; OR THE
SUBJECT QUARTERLY REPORT OR TRANSITION REPORT ON FORM 10-Q, OR PORTION THEREOF
WILL BE FILED ON OR BEFORE THE FIFTH CALENDAR DAY FOLLOWING THE PRESCRIBED DUE
DATE; AND
[ ] (C) THE ACCOUNTANT'S STATEMENT OR OTHER EXHIBIT REQUIRED BY RULE 12B-25(C)
HAS BEEN ATTACHED IF APPLICABLE.
--------------------------------------------------------------------------------
PART III -- NARRATIVE
--------------------------------------------------------------------------------
DURING THE THIRD QUARTER, REPRO-MED SYSTEMS, INC. EXPERIENCED SIGNIFICANT
TURNOVER IN THE ACCOUNTING DEPARTMENT. IN ADDITION, WE EXPERIENCED A COMPLETE
LOSS OF COMPUTER DATA, FOR THE ENTIRE FISCAL YEAR, WHICH IS IN THE PROCESS OF
BEING RE-ENTERED INTO THE GENERAL LEDGER.
--------------------------------------------------------------------------------
PART IV -- OTHER INFORMATION
--------------------------------------------------------------------------------
(1) NAME AND TELEPHONE NUMBER OF PERSON TO CONTACT IN REGARD TO THIS
NOTIFICATION
TRACY RYAN (845) 469-2042
---------- ------------------
(NAME) (TELEPHONE NUMBER)
(2) HAVE ALL OTHER PERIODIC REPORTS REQUIRED UNDER SECTION 13 OR 15(D)
OF THE SECURITIES EXCHANGE ACT OF 1934 OR SECTION 30 OF THE INVESTMENT COMPANY
ACT OF 1940 DURING THE PRECEDING 12 MONTHS OR FOR SUCH SHORTER PERIOD THAT THE
REGISTRANT WAS REQUIRED TO FILE SUCH REPORT(S) BEEN FILED? IF THE ANSWER IS NO,
IDENTIFY REPORT(S).
[X] YES [ ] NO
(3) IS IT ANTICIPATED THAT ANY SIGNIFICANT CHANGE IN RESULTS OF
OPERATIONS FROM THE CORRESPONDING PERIOD FOR THE LAST FISCAL YEAR WILL BE
REFLECTED BY THE EARNINGS STATEMENTS TO BE INCLUDED IN THE SUBJECT REPORT OR
PORTION THEREOF?
[ ] YES [X] NO
IF SO: ATTACH AN EXPLANATION OF THE ANTICIPATED CHANGE, BOTH
NARRATIVELY AND QUANTITATIVELY, AND, IF APPROPRIATE, STATE THE REASONS WHY A
REASONABLE ESTIMATE OF THE RESULTS CANNOT BE MADE.
<PAGE>
REPRO MED SYSTEMS, INC.
(NAME OF REGISTRANT AS SPECIFIED IN CHARTER)
HAS CAUSED THIS NOTIFICATION TO BE SIGNED ON ITS BEHALF BY THE
UNDERSIGNED THEREUNTO DULY AUTHORIZED.
DATE 1/8/01 BY: Andrew Sealfon
------------------------
CHIEF FINANCIAL OFFICER
--------------------------------------------------------------------------------
ATTENTION
INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDERAL
CRIMINAL VIOLATIONS (SEE 18 U.S.C. 1001).
--------------------------------------------------------------------------------
