CHIRON CORP
10-K/A, 1995-04-24
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                            ------------------------
                                   FORM 10-K/A

                                 AMENDMENT NO. 1

/X/           ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE
                 SECURITIES EXCHANGE ACT OF 1934 [FEE REQUIRED]
                                       OR
/ /         TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE
               SECURITIES EXCHANGE ACT OF 1934 [NO FEE REQUIRED]
                  FOR THE FISCAL YEAR ENDED DECEMBER 31, 1994
                          COMMISSION FILE NO. 0-12798
                            ------------------------
                               CHIRON CORPORATION
             (Exact name of Registrant as specified in its charter)

<TABLE>
<S>                                            <C>
                  DELAWARE                                      94-2754624
          (State of Incorporation)                   (IRS Employer Identification No.)
</TABLE>

                               4560 HORTON STREET
                          EMERYVILLE, CALIFORNIA 94608
              (Address of principal executive offices) (Zip Code)

       Registrant's telephone number, including area code: (510) 655-8730
        Securities registered pursuant to Section 12(b) of the Act: None
          Securities registered pursuant to Section 12(g) of the Act:
                          COMMON STOCK, $.01 PAR VALUE
               WARRANTS TO PURCHASE COMMON STOCK, $.01 PAR VALUE

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12  months (or  for such shorter  period that  the Registrant was
required to  file  such  reports), and  (2)  has  been subject  to  such  filing
requirements for the past 90 days.

                            Yes __X__        No ____
Indicate  by check mark if disclosure of  delinquent filers pursuant to Item 405
of Regulation S-K is  not contained herein,  and will not  be contained, to  the
best  of Registrant's knowledge,  in definitive proxy  or information statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K.____
The aggregate  market  value  of  voting stock  held  by  nonaffiliates  of  the
Registrant as of March 1, 1995, was $1,058,210,000.

The  number of shares outstanding of each  of the Registrant's classes of common
stock as of March 1, 1995:

<TABLE>
<CAPTION>
                     TITLE OF CLASS                                           NUMBER OF SHARES
- --------------------------------------------------------  --------------------------------------------------------
<S>                                                       <C>
              Common Stock, $.01 par value                                       40,025,293
</TABLE>

                      DOCUMENTS INCORPORATED BY REFERENCE

The Company's  Consolidated  Financial  Statements for  the  fiscal  year  ended
December  31, 1994, are incorporated  by reference into Parts  II and IV of this
Form 10-K Report and are filed as Exhibit 13 to this Form 10-K Report.

Portions of the  Proxy Statement for  the Annual Meeting  of Stockholders to  be
held  on  May 18,  1995, are  incorporated by  reference into  Part III  of this
Report.

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

<PAGE>

This Amendment No. 1 to Form 10-K is being filed by the Registrant to file as
Exhibit 27 a Financial Data Schedule. All other listed exhibits have previously
been filed.


                                    PART IV

ITEM 14.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K

     (a) 1. FINANCIAL STATEMENTS
         The Consolidated Financial Statements and Notes to Consolidated
     Financial Statements appearing on pages 12-37 of the 1994 Consolidated
     Financial Statements, which is included as Exhibit 13 to the Form 10-K
     Report and the Reports of Independent Auditors appearing on pages 26 and 27
     of the Form 10-K, are incorporated herein by reference.

         2. FINANCIAL STATEMENT SCHEDULES

         Schedule II -- Valuation and Qualifying Accounts

         All other schedules are omitted, since the required information is not
     present or is not present in amounts sufficient to require submission of
     the schedule, or because the information required is included in the
     consolidated financial statements and notes thereto.

     (b) REPORTS ON FORM 8-K
         Chiron filed a current report on Form 8-K dated November 10, 1994,
     reporting under Item 5:

              (1) the issuance of a press release announcing that the Company
         confirmed that it is in discussions with another company regarding a
         potential strategic alliance that would include the other company
         acquiring a very substantial minority equity investment in the Company;
         and

              (2) the issuance of a press release announcing that the Company,
         on behalf of its vaccine joint businesses with Ciba, entered into a
         letter agreement, subject to Federal Trade Commission approval, with
         American Home Products Corporation ("AHP") to purchase AHP's tetanus
         and diphtheria vaccine products.

         Chiron filed a current report on Form 8-K dated November 20, 1994,
     reporting under Item 5 that the Company and Ciba-Geigy Ltd. announced
     the signing of definitive agreements to form a strategic biotechnology
     collaboration that includes the acquisition by Ciba of a 49.9 percent
     interest in the Company.

     (c) EXHIBITS

<TABLE>
<CAPTION>
 EXHIBIT
  NUMBER                                                    EXHIBIT
- ----------  --------------------------------------------------------------------------------------------------------
<C>         <S>
      2.01  Agreement and Plan of Merger, made as of February 6, 1987, incorporated by reference to Exhibit 2.01 of
             the Registrant's Form 10-Q report for the period ended September 30, 1994
      3.01  Restated Certificate of Incorporation of the Registrant, dated August 18, 1987, incorporated by
             reference to Exhibit 3.01 of the Registrant's Form 10-K report for fiscal year 1991
      3.02  Certificate of Amendment of Restated Certificate of Incorporation of the Registrant, dated December 12,
             1991, incorporated by reference to Exhibit 3.01 of the Registrant's Form 10-K report for fiscal year
             1991
      3.03  Bylaws of the Registrant, as amended
      4.01  Indenture, dated as of May 21, 1987, between Cetus Corporation and Bankers Trust Company, Trustee,
             incorporated by reference to Exhibit 4.01 of the Registrants Form 10-Q report for the period ended
             September 30, 1994
      4.02  First Supplemental Indenture, dated as of December 12, 1991, by and among Registrant, Cetus Corporation,
             and Bankers Trust Company, incorporated by reference to Exhibit 4.02 of the Registrant's Form 10-K
             report for fiscal year 1992
      4.03  Indenture, dated as of November 15, 1993, between Registrant and The First National Bank of Boston, as
             Trustee, incorporated by reference to Exhibit 4.03 of the Registrant's Form 10-K report for fiscal year
             1993
      4.04  Rights Agreement, dated as of August 25, 1994, between the Company and Continental Stock Transfer &
             Trust Company, which includes the Certificate of Designations for the Series A Junior Participating
             Preferred Stock as Exhibit A, the form of Right Certificate as Exhibit B and the Summary of Rights to
             Purchase Preferred Shares as Exhibit C, incorporated by reference to Exhibit 4.04 of Registrant's
             report on Form 8-K dated August 25, 1994
      4.05  Amendment No. 1 to Rights Agreement dated as of November 20, 1994, between Chiron Corporation and
             Continental Stock Transfer & Trust Company, incorporated by reference to Exhibit 4.05 of Registrant's
             report on Form 8-K, dated November 20, 1994
     10.01  Lease between Registrant and BGR Associates, a California limited partnership, dated May 26, 1989,
             incorporated by reference to Exhibit 10.01 of the Registrant's Form 10-Q report for the period ended
             September 30, 1994
     10.02  Lease between Registrant and BGR Associates II, a California limited partnership, dated May 26, 1989,
             incorporated by reference to Exhibit 10.02 of the Registrant's Form 10-Q report for the period ended
             September 30, 1994
     10.03  Office Sublease between Sybase, Inc., a California corporation, and Registrant, dated July 18, 1991,
             incorporated by reference to Exhibit 10.03 of the Registrant's Form 10-K report for fiscal year 1992
     10.04  Lease between Registrant and Bay Center Associates, a California limited partnership, dated as of June
             5, 1987, incorporated by reference to Exhibit 10.33 of Registrant's Form 10-K report for fiscal year
             1987
     10.05  Amendment to lease between Registrant and Bay Center Associates, a California limited partnership, dated
             February 4, 1988, incorporated by reference to Exhibit 10.05 of the Registrant's Form 10-Q report for
             the period ended September 30, 1994
     10.06  Amendment to lease between Registrant and J S Bay Center Associates, a California limited partnership,
             dated December 1, 1994
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
 EXHIBIT
  NUMBER                                                    EXHIBIT
- ----------  --------------------------------------------------------------------------------------------------------
<C>         <S>
     10.07  Lease between Acorn Development, Inc., a West Virginia corporation, and IntraOptics, Inc., a Delaware
             corporation, dated September 12, 1991, incorporated by reference to Exhibit 10.06 of the Registrant's
             Form 10-K report for fiscal year 1992
     10.08  License Agreement between the Registrant and the Board of Trustees of the Leland Stanford Junior
             University, dated December 15, 1981, incorporated by reference to Exhibit 10.07 of the Registrant's
             Form 10-Q report for the period ended September 30, 1994
     10.09  Joint Venture Agreement by and between Chiron Biocine Corporation, a California corporation, and
             CIBA-GEIGY Biocine Corporation, a Delaware corporation, dated April 15, 1987 (with certain confidential
             information deleted), incorporated by reference to Exhibit 10.23 of the Registrant's Form 8 filed with
             the Commission on February 14, 1992
     10.10  Amendment to Biocine Joint Venture Agreement by and between Chiron Biocine Corporation, a California
             corporation, and CIBA-GEIGY Biocine Corporation, a Delaware corporation, effective as of January 1,
             1992, incorporated by reference to Exhibit 10.63 to Registrant's Form 10-Q report for the period ended
             June 30, 1992
     10.11  Research and License Agreement by and between Registrant and The Biocine Company, a Delaware
             partnership, dated April 15, 1987 (with certain confidential information deleted), incorporated by
             reference to Exhibit 10.24 of the Registrant's Form 8 filed with the Commission on February 14,
             1992
     10.12  License Agreement by and between CIBA-GEIGY Biocine Corporation, a Delaware corporation, and The Biocine
             Company, a Delaware partnership, dated April 15, 1987 (with certain confidential information deleted),
             incorporated by reference to Exhibit 10.25 of the Registrant's Form 8 filed with the Commission on
             February 14, 1992
     10.13  License Agreement by and between Chiron Biocine Corporation, a California corporation, and The Biocine
             Company, a Delaware partnership, dated April 15, 1987 (with certain confidential information deleted),
             incorporated by reference to Exhibit 10.26 of the Registrant's Form 8 filed with the Commission on
             February 14, 1992
     10.14  Letter Agreement signed by CIBA-GEIGY Corporation, dated April 15, 1987, incorporated by reference to
             Exhibit 10.13 of the Registrant's Form 10-Q report for the period ended September 30, 1994
     10.15  Agreement between the Registrant and Ortho Diagnostic Systems, Inc., a New Jersey corporation, dated
             August 17, 1989, and Amendment to Collaboration Agreement between Ortho Diagnostic Systems, Inc. and
             Registrant, dated December 22, 1989 (with certain confidential information deleted), incorporated by
             reference to Exhibit 10.14 of the Registrant's Form 10-Q report for the period ended September 30, 1994
     10.16  License and Supply Agreement between Ortho Diagnostic Systems, Inc., a New Jersey corporation, the
             Registrant and Abbott Laboratories, an Illinois corporation, dated August 17, 1989 (with certain
             confidential information deleted), incorporated by reference to Exhibit 10.15 of the Registrant's Form
             10-Q report for the quarter ended June 30, 1994
     10.17  Chiron 1991 Stock Option Plan, as amended*
     10.18  Forms of Option Agreements, Chiron 1991 Stock Option Plan, as amended, incorporated by reference to
             Exhibit 10.17 of the Registrant's Form 10-K report for fiscal year 1993*
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
 EXHIBIT
  NUMBER                                                    EXHIBIT
- ----------  --------------------------------------------------------------------------------------------------------
<C>         <S>
     10.19  Forms of Option Agreements, Cetus Corporation Amended and Restated Common Stock Option Plan,
             incorporated by reference to Exhibit 10.33 of Registrant's Form 10-K report for fiscal year 1991*
     10.20  Forms of Supplemental Letter concerning the assumption of Cetus Corporation options by Chiron,
             incorporated by reference to Exhibit 10.34 of Registrant's Form 10-K report for fiscal year 1991*
     10.21  Agreement and Plan of Reorganization dated as of October 11, 1991 by and among the Registrant, Chiron
             Ophthalmics, Inc., COI Acquisition Corp., IntraOptics, Inc. and James R. Cook, M.D., incorporated by
             reference to Exhibit 28.2 of Registrant's report on Form 8-K dated October 14, 1991
     10.22  Indemnification Agreement between the Registrant and Dr. William J. Rutter, dated as of February 12,
             1987 (which form of agreement is used for each member of Registrant's Board of Directors), incorporated
             by reference to Exhibit 10.21 of the Registrant's Form 10-Q report for the period ended September 30,
             1994
     10.23  Stock Purchase Agreement by and between the Registrant and Johnson & Johnson Development Corporation, a
             corporation organized and existing under the laws of the State of New Jersey, dated as of October 3,
             1986, incorporated by reference to Exhibit 10.22 of the Registrant's Form 10-Q report for the period
             ended September 30, 1994
     10.24  Stock Purchase Agreement between the Registrant and CIBA-GEIGY, Limited, a corporation organized and
             existing under the laws of Switzerland, dated November 14, 1988, incorporated by reference to Exhibit
             10.23 of the Registrant's Form 10-Q report for the period ended September 30, 1994
     10.25  Form of Debenture Purchase Agreement between the Registrant and CIBA-GEIGY, Limited, a corporation
             organized and existing under the laws of Switzerland, dated June 22, 1990
     10.26  Chiron Corporation 1.90% Convertible Subordinated Note due 2000, Series B, incorporated by reference to
             Exhibit 10.25 of the Registrant's Form 10-K report for fiscal year 1993
     10.27  Shareholders Agreement, dated as of February 28, 1992, by and among Chiron Corporation, CIBA-GEIGY
             Limited and JV VAX B.V., incorporated by reference to Exhibit 10.40 of Registrant's Form 10-K report
             for fiscal year 1991
     10.28  Investment Agreement dated as of November 20, 1994 among Ciba-Geigy Limited, Ciba-Geigy Corporation,
             Ciba Biotech Partnership, Inc. and Chiron Corporation, incorporated by reference to Exhibit 10.54 of
             the Registrant's current report on Form 8-K dated November 20, 1994
     10.29  Governance Agreement dated as of November 20, 1994 among Ciba-Geigy Limited, Ciba-Geigy Corporation and
             Chiron Corporation, incorporated by reference to Exhibit 10.55 of the Registrant's current report on
             Form 8-K dated November 20, 1994
     10.30  Subscription Agreement dated as of November 20, 1994 among Ciba-Geigy Limited, Ciba-Geigy Corporation,
             Ciba Biotech Partnership, Inc. and Chiron Corporation, incorporated by reference to Exhibit 10.56 of
             the Registrant's current report on Form 8-K dated November 20, 1994
     10.31  Cooperation and Collaboration Agreement dated as of November 20, 1994, between Ciba-Geigy Limited and
             Chiron Corporation, incorporated by reference to Exhibit 10.57 of the Registrant's current report on
             Form 8-K dated November 20, 1994
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
 EXHIBIT
  NUMBER                                                    EXHIBIT
- ----------  --------------------------------------------------------------------------------------------------------
<C>         <S>
     10.32  Registration Rights Agreement dated as of November 20, 1994 between Ciba Biotech Partnership, Inc. and
             Chiron Corporation, incorporated by reference to Exhibit 10.58 of the Registrant's current report on
             Form 8-K dated November 20, 1994
     10.33  Market Price Option Agreement dated as of November 20, 1994 among Ciba-Geigy Limited, Ciba-Geigy
             Corporation, Ciba Biotech Partnership, Inc. and Chiron Corporation, incorporated by reference to
             Exhibit 10.59 of the Registrant's current report on Form 8-K dated November 20, 1994
     10.34  Amendment dated as of January 3, 1995 among Ciba-Geigy Limited, Ciba-Geigy Corporation, Ciba Biotech
             Partnership, Inc. and Chiron Corporation, incorporated by reference to Exhibit 10.60 of the
             Registrant's current report on Form 8-K dated January 4, 1995
     10.35  Supplemental Agreement dated as of January 3, 1995 among Ciba-Geigy Limited, Ciba-Geigy Corporation,
             Ciba Biotech Partnership, Inc. and Chiron Corporation, incorporated by reference to Exhibit 10.61 of
             the Registrant's current report on Form 8-K dated January 4, 1995
     10.36  Amendment with Respect to Employee Stock Option Arrangements dated as of January 3, 1995 among
             Ciba-Geigy Limited, Ciba-Geigy Corporation, Ciba Biotech Partnership, Inc. and Chiron Corporation,
             incorporated by reference to Exhibit 10.62 of the Registrant's current report on Form 8-K dated January
             4, 1995*
     10.37  Supplemental Benefits Agreement, dated July 21, 1989, between the Registrant and Dr. William J. Rutter,
             incorporated by reference to Exhibit 10.27 of the Registrant's Form 10-Q report for the period ended
             September 30, 1994*
     10.38  Lease dated as of July 1, 1983 between Cetus Corporation and H.B. Chapman, Jr., incorporated by
             reference to Exhibit 10.28 of the Registrant's Form 10-Q report for the period ended September 30, 1994
     10.39  Amendment to Lease, dated as of March 20, 1990, amending Lease dated as of July 1, 1983, incorporated by
             reference to Exhibit 10(b) of Cetus Corporation's Form 10-K report for its fiscal year 1990
     10.40  Lease commencing March 1, 1987, between EuroCetus B.V. and the Municipal Land Company of the City of
             Amsterdam (Translation), incorporated by reference to Exhibit 10(k) of Cetus Corporation's Form 10-K
             report for its fiscal year 1987 (Commission File No. 0-10003)
     10.41  Agreement commencing January 1, 1991, between Euro Cetus B.V. and the Municipal Development Corporation
             (Translation)
     10.42  Form of Option Agreement (with Purchase Agreements attached thereto) between Cetus Corporation and each
             former limited partner of Cetus Healthcare Limited Partnership, a California limited partnership,
             incorporated by reference to Exhibit 10.31 of the Registrant's Form 10-Q report for the period ended
             September 30, 1994
     10.43  Form of Option Agreement (with forms of Purchase Agreements attached thereto), dated December 30, 1986,
             between Cetus Corporation and each former limited partner of Cetus Healthcare Limited Partnership II, a
             California limited partnership, incorporated by reference to Exhibit 10.32 of the Registrant's Form
             10-Q report for the period ended September 30, 1994
     10.44  Big-O Property Purchase and Leaseback Agreement, dated as of October 31, 1988, between Cetus Corporation
             and Richard K. Robbins, incorporated by reference to Exhibit 10.33 of the Registrant's Form 10-Q report
             for the period ended September 30, 1994
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
 EXHIBIT
  NUMBER                                                    EXHIBIT
- ----------  --------------------------------------------------------------------------------------------------------
<C>         <S>
     10.45  Triple Net Lease dated as of January 20, 1989, between Cetus Corporation and BGR Associates III, a
             California limited partnership, and Marin County Exchange Corporation, incorporated by reference to
             Exhibit 10.34 of the Registrant's Form 10-Q report for the period ended September 30, 1994
     10.46  Lease entered into as of November 15, 1993 between Hollis R&D Associates, a California General
             Partnership, and Registrant, incorporated by reference to Exhibit 10.35 of the Registrant's Form 10-K
             report for fiscal year 1993
     10.47  Stock Purchase and Warrant Agreement dated May 9, 1989, between Cetus Corporation and Hoffmann-La Roche
             Inc., incorporated by reference to Exhibit 10.36 of the Registrant's Form 10-Q report for the period
             ended September 30, 1994
     10.48  Letter Agreement, dated as of December 12, 1991, relating to Stock Purchase and Warrant Agreement
             between Registrant and Hoffmann-La Roche Inc., incorporated by reference to Exhibit 10.59 of
             Registrant's Form 10-K report for fiscal year 1991
     10.49  Agreement and Plan of Merger dated as of July 21, 1991, by and among Registrant, Chiron Acquisition
             Subsidiary, Inc. and Cetus Corporation, incorporated by reference to Exhibit 28.2 of Registrant's Form
             8-K report dated July 22, 1991
     10.50  Letter Agreement dated September 26, 1990 between the Registrant and William G. Green, incorporated by
             reference to Exhibit 10.41 of the Registrant's Form 10-K report for fiscal year 1992*
     10.51  Letter Agreement dated December 18, 1991 between Registrant and Jack Schuler, incorporated by reference
             to Exhibit 10.42 of the Registrant's Form 10-K report for fiscal year 1992*
     10.52  Letter Agreement dated May 7, 1992 between Registrant and Donald A. Glaser, incorporated by reference to
             Exhibit 10.43 of the Registrant's Form 10-K report for fiscal year 1992*
     10.53  Letter Agreement dated March 12, 1993 between the Registrant and William G. Gerber, incorporated by
             reference to Exhibit 10.46 of the Registrant's Form 10-K report for fiscal year 1992*
     10.54  Letter Agreement dated September 9, 1991 between the Registrant and Walter Moos, incorporated by
             reference to Exhibit 10.47 of the Registrant's Form 10-K report for fiscal year 1992*
     10.55  Letter Agreement between the Registrant and Walter Moos, dated February 1, 1993, incorporated by
             reference to Exhibit 10.48 of the Registrant's Form 10-K report for fiscal year 1992*
     10.56  Letter Agreement between Registrant and Renato Fuchs, dated May 13, 1993, incorporated by reference to
             Exhibit 10.47 of the Registrant's Form 10-K report for fiscal year 1993*
     10.57  Letter Agreement between Registrant and David Martin, dated December 2, 1993, incorporated by reference
             to Exhibit 10.48 of the Registrant's Form 10-K report for fiscal year 1993*
     10.58  Description of Executive Variable Compensation Program*
     10.59  Chiron Corporation Executive Bonus Plan*
     10.60  Regulatory Filing, Development and Supply Agreement between the Registrant, Cetus Oncology Corporation,
             a wholly owned subsidiary of the Registrant, and Schering AG, a German company, dated as of May 10,
             1993 (with certain confidential information deleted), incorporated by reference to Exhibit 10.50 of the
             Registrant's Form 8-K report dated February 9, 1994
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
 EXHIBIT
  NUMBER                                                    EXHIBIT
- ----------  --------------------------------------------------------------------------------------------------------
<C>         <S>
     10.61  Letter Agreement dated December 30, 1993 by and between Registrant and Schering AG, a German company
             (with certain confidential information deleted), incorporated by reference to Exhibit 10.51 of the
             Registrant's Form 10-K report for fiscal year 1993
     10.62  Guaranty, dated as of September 29, 1994, made by Registrant, in favor of Bankers Trust Company, as
             trustee, incorporated by reference to Exhibit 10.52 of the Registrant's Form 10-Q report for the period
             ended September 30, 1994
     10.63  Guaranty, dated as of September 29, 1994, made by Cetus Corporation, in favor of The First National Bank
             of Boston, as trustee, incorporated by reference to Exhibit 10.53 of the Registrant's Form 10-Q report
             for the period ended September 30, 1994
     10.64  Letter Agreements dated September 11, 1992, July 15, 1994 and September 14, 1994 between the Registrant
             and Lewis T. Williams, incorporated by reference to Exhibit 10.54 of the Registrant's Form 10-Q report
             for the period ended September 30, 1994*
     10.65  Letter dated January 4, 1995 to C. William Zadel*
     10.66  Letter to Dino Dina dated April 24, 1984*
     11     Statement of Computation of Earnings per Share
     13     Consolidated Financial Statements
     21     List of Subsidiaries of the Registrant
     23.1   Consent of KPMG Peat Marwick LLP, Independent Auditors. Reference is made to page 28 of the Form 10-K
             report
     23.2   Consent of Ernst & Young LLP, Independent Auditors. Reference is made to page 29 of the Form 10-K
             report
     24     Power of Attorney. Reference is made to pages 24-25 of the Form 10-K report
     27     Financial Data Schedule

<FN>
- ------------------------
* Management contract, compensatory plan or arrangement.
</TABLE>








<PAGE>
                                   SIGNATURES

    Pursuant  to  the requirements  of  Section 13  or  15(d) of  the Securities
Exchange Act of 1934, the Registrant has duly caused this Amendment No. 1 to the
Report to be signed on its behalf by the undersigned, thereunto duly authorized.

    Date: April 21, 1995

                                          CHIRON CORPORATION

                                          By        EDWARD E. PENHOET

                                             -----------------------------------
                                                  Edward E. Penhoet, Ph.D.
                                                PRESIDENT AND CHIEF EXECUTIVE
                                                           OFFICER
/
<PAGE>

    Pursuant to the  requirements of the  Securities Exchange Act  of 1934,  the
Report  has  been  signed  below  by the  following  persons  on  behalf  of the
Registrant and in the capacities and on the dates indicated.

<TABLE>
<CAPTION>
             SIGNATURE                         TITLE                  DATE
- -----------------------------------  -------------------------  ----------------
<C>                                  <S>                        <C>

           EDWARD E. PENHOET
- -----------------------------------   President and Chief         April 21, 1995
     Edward E. Penhoet, Ph.D.         Executive Officer

                                      Senior Vice President,
                                      Finance and
         DENNIS L. WINGER*            Administration, Chief
- -----------------------------------   Financial Officer, and      April 21, 1995
         Dennis L. Winger             Principal Accounting
                                      Officer

           WILLIAM J. RUTTER*
- -----------------------------------   Chairman of the Board of    April 21, 1995
     William J. Rutter, Ph.D.         Directors

            GILBERT AMELIO*
- -----------------------------------   Director                    April 21, 1995
       Gilbert Amelio, Ph.D.

           LEWIS W. COLEMAN*
- -----------------------------------   Director                    April 21, 1995
         Lewis W. Coleman

             PIERRE DOUAZE*
- -----------------------------------   Director                    April 21, 1995
           Pierre Douaze

           DONALD A. GLASER*
- -----------------------------------   Director                    April 21, 1995
      Donald A. Glaser, Ph.D.

              ALEX KRAUER*
- -----------------------------------   Director                    April 21, 1995
        Alex Krauer, Ph.D.

        FRANCOIS L'EPLATTENIER*
- -----------------------------------   Director                    April 21, 1995
   Francois L'Eplattenier, Ph.D.

            HENRI SCHRAMEK*
- -----------------------------------   Director                    April 21, 1995
       Henri Schramek, Ph.D.

            JACK W. SCHULER*
- -----------------------------------   Director                    April 21, 1995
          Jack W. Schuler

          PIETER J. STRIJKERT*
- -----------------------------------   Director                    April 21, 1995
    Pieter J. Strijkert, Ph.D.


* By      EDWARD E. PENHOET
- -----------------------------------
          Edward E. Penhoet
          ATTORNEY-IN-FACT

</TABLE>



<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM CHIRON
CORPORATION'S CONSOLIDATED BALANCE SHEET DATED DECEMBER 31, 1994 AND
CONSOLIDATED STATEMENT OF OPERATIONS FOR THE YEAR ENDED DECEMBER 31, 1994 AND
NOTES THERETO AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL
STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1994
<PERIOD-START>                             JAN-01-1994
<PERIOD-END>                               DEC-31-1994
<CASH>                                          84,876
<SECURITIES>                                   308,947<F1>
<RECEIVABLES>                                  140,476
<ALLOWANCES>                                     7,210
<INVENTORY>                                     47,592
<CURRENT-ASSETS>                               433,815
<PP&E>                                         362,511
<DEPRECIATION>                                  76,337
<TOTAL-ASSETS>                               1,049,742
<CURRENT-LIABILITIES>                          119,641
<BONDS>                                        341,522<F2>
<COMMON>                                           334
                                0
                                          0
<OTHER-SE>                                     572,297<F3>
<TOTAL-LIABILITY-AND-EQUITY>                 1,049,742
<SALES>                                        275,966
<TOTAL-REVENUES>                               453,979
<CGS>                                          128,209
<TOTAL-COSTS>                                        0
<OTHER-EXPENSES>                               283,370<F4>
<LOSS-PROVISION>                                 5,880
<INTEREST-EXPENSE>                              20,186
<INCOME-PRETAX>                                 31,997
<INCOME-TAX>                                    13,672
<INCOME-CONTINUING>                             18,325
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                    18,325
<EPS-PRIMARY>                                     0.53
<EPS-DILUTED>                                     0.53
<FN>
<F1>CONSISTS OF BOTH LONG-TERM AND SHORT-TERM INVESTMENTS IN MARKETABLE DEBT
SECURITIES.
<F2>CONSISTS OF CONVERTIBLE SUBORDINATED DEBENTURES, CAPITAL LEASES AND NOTES
PAYABLE.
<F3>CONSISTS OF ADDITIONAL PAID-IN CAPITAL, ACCUMULATED DEFICIT, CUMULATIVE FOREIGN
CURRENCY TRANSLATION ADJUSTMENT AND UNREALIZED LOSS FROM INVESTMENTS.
<F4>CONSISTS OF RESEARCH, DEVELOPMENT, SELLING, GENERAL, ADMINISTRATIVE AND OTHER
OPERATING EXPENSES.
</FN>
        

</TABLE>


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