ALPHA 1 BIOMEDICALS INC
PRER14A, 1998-03-27
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
                 CONFIDENTIAL -- FOR USE OF THE COMMISSION ONLY

                            SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                               (Amendment No. 1)

Filed by the Registrant [X]
Filed by a Party other than the Registrant [ ]
Check the appropriate box:
[X] Preliminary Proxy Statement
[X] Confidential, for Use of the Commission Only (as permitted by Rule
    14a-6(e)(2))
[ ] Definitive Proxy Statement
[ ] Definitive Additional Materials
[ ] Soliciting Material Pursuant to Section 240.14a-11(c)or Section 240.14a-12

                            Alpha 1 Biomedicals, Inc.
                (Name of Registrant as Specified In Its Charter)

- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):
[ ] No fee required.
[X] Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

    1)   Title of each class of securities to which transaction applies:

         -----------------------------------------------------------------------

    2)   Aggregate number of securities to which transaction applies:

         -----------------------------------------------------------------------

    3)   Per unit price or other underlying value of transaction computed
         pursuant to Exchange Act Rule 0-11 (set forth the amount on which
         the filing fee is calculated and state now it was determined):
          $1,930,000  (based on the fair market value of the consideration to be
          received from sale of substantial part of assets)
         -----------------------------------------------------------------------

    4)   Proposed maximum aggregate value of transaction:
          $1,930,000
         -----------------------------------------------------------------------

    5)   Total fee paid:

[ ] Fee paid previously with preliminary materials.

[ ] Check box if any part of the fee is offset as provided by Exchange
    Act Rule 0-11(a)(2) and identify the filing for which the offsetting
    fee was paid previously. Identify the previous filing by registration
    statement number, or the Form or Schedule and the date of its filing:

    1)   Amount previously paid:
          $386.00
         --------------------------------------------

    2)   Form, Schedule or Registration Statement No:

         --------------------------------------------

    3)   Filing party:

         --------------------------------------------

    4)   Date filed:

         --------------------------------------------


<PAGE>   2


[LOGO]

6707 Democracy Boulevard, Suite 111
Bethesda, MD 20817
301/564-4400 - Fax 301/564-4424

                                                                  March___, 1998

Dear Stockholder:

        You are cordially invited to attend the Annual Meeting of Shareholders
of Alpha 1 Biomedicals, Inc. (the "Company") to be held at
[____________________________] commencing at _____, on ________, April___, 1998.

        At this important meeting, the stockholders will be asked to approve the
sale by the Company to SciClone Pharmaceuticals, Inc. ("SciClone") of the
Company's rights to receive royalty payments from the future sale by SciClone
and its licensees of Thymosin alpha 1. In exchange the Company will receive
payments in cash totaling $130,000 and at least 444,115 shares of SciClone
Common Stock. The Company's Board of Directors believes that the transaction
with SciClone is the only transaction currently available to the Company that
will allow the Company to continue as a going concern. On this basis, the Board
of Directors has concluded that the transaction is in the best interests of the
Company and its stockholders. Approval of the SciClone transaction requires the
approval of the holders of a majority of the outstanding shares of Common Stock.
Accordingly, your vote is important no matter how many shares you own.

        At the meeting, the stockholders also will be asked to vote on an
amendment to the Certificate of Incorporation to increase the number of
authorized shares from 20 million to 75 million, and to ratify the appointment
of Price Waterhouse LLP as the independent auditors for the fiscal year ended
December 31, 1998

        The Secretary's formal notice of the meeting and the Proxy Statement
appear on the following pages and describe the other matters that will be
submitted to a vote of stockholders at the meeting. During the meeting, time
will be provided for a review of the Company's activities over the past year and
for stockholders' questions.

        We hope that you will be able to attend this important meeting in
person, and we look forward to seeing you. If you cannot attend, please mark,
date, and sign the enclosed proxy card and return it in the accompanying
envelope at your earliest convenience to assure your shares will be represented
and voted at the Annual Meeting. If you attend, you may revoke your proxy and
vote in person if you so desire.

                                Sincerely,

                                Michael L. Berman
                                President and Chief Executive Officer


<PAGE>   3


                            ALPHA 1 BIOMEDICALS, INC.
                       6707 DEMOCRACY BOULEVARD, SUITE 111
                               BETHESDA, MD 20817

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

                        TO BE HELD ON ________ ___, 1998

        Notice is hereby given that the Annual Meeting of Stockholders of Alpha
1 Biomedicals, Inc. will be held at _______________________, commencing at
_____, on ________, April ___, 1998. At the Annual Meeting, the following
matters will be submitted to a vote of the stockholders:

               1.     To elect a Board of Directors consisting of four 
                      directors;

               2.     To consider and vote upon a proposal to approve the sale
                      to SciClone Pharmaceuticals, Inc. of the Company's rights
                      to receive royalties from the sale of Thymosin alpha 1;

               3.     To consider and vote upon a proposal to approve an
                      amendment to the Company's Restated Certificate of
                      Incorporation to increase the authorized shares of Common
                      Stock from 20 million to 75 million;

               4.     To consider and vote upon a proposal to ratify the
                      appointment of Price Waterhouse LLP as independent
                      auditors for the fiscal year ending December 31, 1998; and

               5.     To transact such other business as may properly be brought
                      before the meeting.

        The Board of Directors has fixed ________________, as the record date
for the meeting. Only stockholders of record at the close of business on that
date are entitled to receive notice of and vote at the meeting.

        YOUR PROXY IS IMPORTANT TO ENSURE A QUORUM AT THE MEETING. EVEN IF YOU
OWN ONLY A FEW SHARES, AND WHETHER OR NOT YOU EXPECT TO BE PRESENT, YOU ARE
URGED TO MARK, DATE, AND SIGN THE ENCLOSED PROXY CARD AND RETURN IT IN THE
POSTAGE-PAID ENVELOPE PROVIDED. YOU MAY REVOKE YOUR PROXY PRIOR TO THE TIME THAT
VOTES ARE CAST AT THE MEETING. THE GIVING OF YOUR PROXY WILL NOT PREVENT YOU
FROM VOTING IN PERSON AT THE MEETING IF YOU CHOOSE TO DO SO.

                                By Order of the Board of Directors,

                                Robert J. Lanham
                                Secretary

Bethesda, Maryland
March ___, 1998


<PAGE>   4


                                 PROXY STATEMENT

                               GENERAL INFORMATION

        The enclosed proxy is being solicited by the Board of Directors of Alpha
1 Biomedicals, Inc., a Delaware corporation (the "Company"), for use at the
Annual Meeting of Stockholders to be held at ______________________, at
_________, on ____________ __, 1998. Only stockholders of record at the close of
business on _____, 1998 (the "Record Date"), will be entitled to vote at the
meeting. On the Record Date, there were issued and outstanding 11,977,429 shares
of common stock, par value $.001 per share ("Common Stock"). A majority of the
outstanding shares of Common Stock, present in person or represented by proxy,
will constitute a quorum for the transaction of business at the meeting.

MATTERS SUBJECT TO VOTE.

        At the Annual Meeting, the Company intends to submit the following
matters to a vote of the stockholders:

        (1) The election of four directors to serve until the next annual
meeting and until his successor is elected and qualified. See "Election of
Directors."

        (2) Approval of the sale by the Company to SciClone Pharmaceuticals,
Inc. ("SciClone") of the Company's rights to receive royalty payments from the
future sale by SciClone and its sublicensees of Thymosin alpha 1 (the "SciClone
Transaction"). Pursuant to the terms and conditions of the Alpha Rights
Acquisition Agreement, dated as of December 17, 1997, (the "Acquisition
Agreement"), between the Company and SciClone, the Company will receive in
exchange for its royalty rights $130,000 in cash and 444,115 shares of SciClone
Common Stock, no par value per share ("SciClone Common Stock"). The number of
shares was calculated based on a price of $4.053. If the market price of the
SciClone Common Stock is lower than $4.053 when the shares become available for
sale by the Company, the Company is entitled to receive up to 155,855 additional
shares. The Company expects to sell the shares of SciClone Common Stock in order
to fund current operations and to pay vendor obligations. The cash realized by
the Company from the sale of the shares will depend on the market price when the
shares are sold, which could be less than $4.053. On March 20, 1998, the market
price of the SciClone Common Stock was $3.25. See "Sale of Thymosin Alpha 1
Royalty Rights."

        The following factors should be taken into account by stockholders in
connection with their consideration of the SciClone Transaction:

        -      After the transaction, the Company will have no revenue
               generating assets other than the SciClone Common Stock.

        -      The Company's current liabilities as of the closing of the
               SciClone Transaction will be approximately $1.4 million. If
               following the closing, the SciClone Common Stock maintains an
               average monthly market price of $3.00 per share, the Company
               expects to be able to pay these obligations and to continue
               operations until approximately the fourth quarter of 1998.
               However, if the average monthly market price is less than $3.00,
               the Company may not be able to meet its obligations and will
               require financing at an earlier time in order to sustain its
               operations.


                                      -1-
<PAGE>   5


        -      The ability of the Company to resell the SciClone Common Stock
               without restriction will depend upon the registration by SciClone
               of the shares for resale with the Securities and Exchange
               Commission.

        -      The Company has not sought or obtained either an independent
               determination of the potential value of the Company's Thymosin
               alpha 1 royalty rights or an opinion as to the fairness of the
               SciClone Transaction to the Company and its stockholders.

        -      The Company's stockholders will not have appraisal rights with
               respect to the transaction.

        (3) Approval of an amendment to the Company's Restated Certificate of
Incorporation, as amended (the "Certificate of Incorporation"), to increase the
number of authorized shares of Common Stock from 20,000,000 to 75,000,000. See
"Amendment to Certificate of Incorporation."

        (4) Ratification of the appointment of Price Waterhouse LLP to serve as
the Company's independent auditors for the year ending December 31, 1998. See
"Ratification of Appointment of Independent Auditors."

VOTING OF PROXIES.

        Proxies in the accompanying form that are properly executed and returned
to the Company, and that are not subsequently revoked, will be voted in the
manner specified by the stockholder on the proxy card. If a proxy is properly
executed, but does not specify how the shares represented thereby are to be
voted on any matter being submitted to a vote of stockholders, the proxy will be
voted on the matter or matters for which instructions are not received as
follows: (i) FOR the election as directors of each of the nominees identified in
this Proxy Statement; (ii) FOR the SciClone Transaction; (iii) FOR the amendment
to the Certificate of Incorporation to increase the number of authorized shares
of Common Stock; (iv) FOR the ratification of Price Waterhouse LLP as
independent auditors of the Company for the year ending December 31, 1998; and
(v) in the discretion of the persons named as proxies as to any other matter
that may properly come before the meeting. A proxy may be revoked by a
stockholder at any time before its exercise by delivery to the Secretary of the
Company of either a written revocation or a subsequently dated proxy and will be
deemed revoked if the stockholder votes in person at the Annual Meeting.

        Adoption of the proposals to approve the SciClone Transaction and to
approve the amendment of the Certificate of Incorporation each requires the
affirmative vote of the holders of a majority of the issued and outstanding
shares of Common Stock. For each of these votes, both abstentions and shares
held in "street name" that are not voted by a broker or other nominee because of
the absence of discretionary voting authority, so-called "broker non-votes,"
will constitute "no" votes. For purposes of each vote that requires for adoption
the affirmative vote of a majority of the shares present and entitled to vote,
(i) shares as to which a holder abstains from voting effectively constitute "no"
votes because such shares are considered present and entitled to vote at the
meeting and (ii) shares held in "street name" by a broker or nominee who does
not have discretionary authority to vote such shares on the particular matter
are not counted as shares entitled to vote on such matter.

GENERAL MATTERS.

        The cost of this proxy solicitation is being borne by the Company. In
addition to solicitation by mail, the Company will request banks, brokers and
other custodial nominees and fiduciaries to supply proxy


                                      -2-
<PAGE>   6


material to the beneficial owners of the Common Stock of whom they have
knowledge, and will reimburse them for their expenses in so doing. Officers and
other employees of the Company may solicit proxies personally, by telephone or
by mail, without receiving any additional compensation for such activities.

        The address of the Company is 6707 Democracy Boulevard, Suite 111,
Bethesda, Maryland 20817. The Company's telephone number at that address is
(301) 564-4400.

        The mailing of this Proxy Statement and the form of proxy will commence
on or about March____, 1998.


                                      -3-
<PAGE>   7


                              ELECTION OF DIRECTORS

        The four individuals listed below each have been nominated for election
as a director at the 1998 Annual Meeting, to hold office until the next annual
meeting of stockholders and until his successor is elected and qualified. Unless
authority to vote for directors is withheld in the accompanying proxy, the
persons named therein as proxies will vote FOR the election of each of the four
nominees listed below. Directors will be elected by a plurality of the votes
cast. All nominees for election have indicated a willingness to serve, but if
any of them should decline or be unable to serve as a director, the persons
named as proxies intend to vote all shares in favor of the election of such
other person nominated as a replacement by the Board of Directors. If no such
other person is designated as a replacement, the Board of Directors will reduce
the number of directors to be elected.

<TABLE>
<CAPTION>
NAME                             AGE     POSITIONS WITH THE COMPANY
- ----                             ---     --------------------------
<S>                              <C>     <C>
Allan L. Goldstein............   60      Chairman of the Board of Directors

Michael L. Berman, Ph.D.......   48      President and Chief Executive Officer

Joseph C. McNay...............   64      Director

Albert Rosenfeld..............   77      Director
</TABLE>

        Set forth below, as to each nominee, is information concerning the
period of service as a director of the Company, a brief description of his
principal occupation and business experience during the past five years, and
certain other directorships held.

        ALLAN L. GOLDSTEIN, PH.D. Dr. Goldstein has been the Chairman of the
Board of the Company since its founding in May 1982. He is the Chairman of the
Department of Biochemistry and Molecular Biology at The George Washington
University School of Medicine and Health Sciences, a position he has held since
1978. Prior to July 1986, Dr. Goldstein served as Chief Executive Officer and
Treasurer of the Company.

        MICHAEL L. BERMAN, PH.D. Dr. Berman was elected as President and Chief
Executive Officer of the Company in November 1994. He has been a director of the
Company since April 1995. Dr. Berman joined the Company in early 1994 as Vice
President for new commercial programs. From 1988 to 1993, Dr. Berman was Vice
President and Scientific Director and then Director of Business Development with
Oncologix, Inc. He is a director of Prototek, Inc. and Peptomers, Inc.

        JOSEPH C. MCNAY Mr. McNay has served as a member of the Board of
Directors since 1987. Mr. McNay has been the Chairman and director of Essex
Investment Management Company, Inc., a registered investment adviser, since
1976. He is a director of Softech, Inc. and MPSI Systems, Inc.

        ALBERT ROSENFELD Mr. Rosenfeld has served as a member of the Board of
Directors since 1982. Mr. Rosenfeld has been a consultant on Future Programs for
the March of Dimes Birth Defects Foundation since 1973 and Adjunct Professor in
the Department of Human Biological Chemistry and Genetics at the University of
Texas Medical Branch, Galveston, Texas since 1974. He is a frequent author and
lecturer on scientific matters.


                                      -4-
<PAGE>   8


THE BOARD OF DIRECTORS RECOMMENDS THE ELECTION AS DIRECTORS OF EACH OF THE
NOMINEES.

MEETING ATTENDANCE.

        The Board of Directors met five times during 1997. Each of the
directors, with the exception of Mr. McNay, was present for 75% or more of the
total number of meetings held during the year by the Board of Directors and by
each committee of the Board on which such director served. Mr. McNay attended
three of the five Board meetings.

COMMITTEES OF THE BOARD.

        The Audit Committee and the Stock Option Committee are the only standing
committees of the Board of Directors. The Company does not have a compensation
committee or a nominating committee.

        The function of the Audit Committee is to assure that appropriate audits
of the Company's affairs are conducted. In carrying out this responsibility, the
Audit Committee meets periodically with management and representatives of the
Company's independent auditors and reviews the scope of internal and external
audit activities and the results of the annual audit. The independent auditors
have direct access to the Audit Committee to discuss the results of their
examination, the adequacy of the internal accounting controls and the integrity
of financial reporting. The members of the Audit Committee are Mr. McNay and Mr.
Rosenfeld. The Audit Committee did not meet during 1997.

        The Stock Option Committee is responsible for administering the
Company's employee stock option plans and in this capacity approves all stock
option grants to executive officers of the Company. The members of the Stock
Option Committee are Mr. McNay and Mr. Rosenfeld. The Stock Option Committee did
not meet in 1997, but on one occasion acted by unanimous written consent.

DIRECTOR COMPENSATION.

        Each nonemployee director is paid an annual fee of $5,000, plus $1,250
per meeting for each meeting attended in person and is reimbursed for expenses
incurred in attending Board meetings. Each current nonemployee director (and any
new nonemployee director) is a participant in the Company's Directors Stock
Option Plan pursuant to which (i) each nonemployee director at the time of his
or her initial election or appointment is granted an option to purchase 10,000
shares of Common Stock and (ii) each nonemployee director receives annually an
option to purchase 5,000 shares of Common Stock at the time of his or her
reelection as a director. All such options have an exercise price equal to the
fair market value of the Common Stock on the date of the grant and vest in
annual increments of 20% beginning on the date of the grant.

EXECUTIVE COMPENSATION.

        SUMMARY COMPENSATION TABLE. The following table sets forth certain
information concerning the compensation for each of the last three fiscal years
of the individual who in 1997 served as the Company's President and Chief
Executive Officer and each other executive officer of the Company whose combined
1997 salary and bonus exceeded $100,000 (the "named executive officers").


                                      -5-
<PAGE>   9


<TABLE>
<CAPTION>
                                                                         LONG TERM
                                                        ANNUAL          COMPENSATION
                                                    COMPENSATION(1)        AWARDS
NAME AND                                            ---------------        ------         ALL OTHER
PRINCIPAL POSITION                         YEAR    SALARY      BONUS     OPTIONS(2)     COMPENSATION
- ------------------                         ----    ------      -----     ----------     ------------
<S>                                        <C>     <C>         <C>       <C>            <C>
Michael L. Berman......................    1997    $ 149,820   $     0    682,682        $ 2,960(3)
    President and                          1996    $ 149,820   $     0          0        $ 2,591(4)
    Chief Executive Officer                1995    $ 150,109   $ 5,000    580,000(2)     $ 8,241(5)

Robert J. Lanham.......................    1997    $ 114,821   $     0    227,561        $ 5,040(6)
    Vice President, Finance                1996    $ 105,968   $     0          0        $ 4,738(7)
    and Chief Financial Officer            1995    $ 113,211   $     0    215,000(2)     $ 8,255(8)
</TABLE>

(1)     None of the above-named executive officers received in any of the
        identified years perquisites or other personal benefits in excess of the
        lesser of $50,000 or 10% of such individual's combined salary and bonus
        for that year.

(2)     Includes options issued to Dr. Berman and Mr. Lanham to purchase 500,000
        and 200,000 shares of Common Stock, respectively, that were granted
        subject to stockholder approval of a proposed merger of the Company. The
        proposed merger transaction was terminated in 1996 by mutual agreement
        of the parties, and as a result the options were canceled.

(3)     Consists of $2,960 of premiums paid by the Company for long-term
        disability and life insurance.

(4)     In 1996, consists of (i) $865 in contributions to the Company's 401(k)
        plan and (ii) $1,726 paid by the Company for long-term disability
        insurance.

(5)     In 1995, consists of (i) $4,620 in matching contributions to the
        Company's 401(k) plan and (ii) $3,621 paid by the Company for long-term
        disability and life insurance.

(6)     Consists of $5,040 of premiums paid by the Company for long-term
        disability and life insurance.

(7)     In 1996, consists of (i) $663 in contributions to the Company's 401(k)
        plan and (ii) $4,075 paid by the Company for long-term disability and
        file insurance.

(8)     In 1995, consists of (i) $4,620 in matching contributions to the
        Company's 401(k) plan and (ii) $3,635 paid by the Company for long-term
        disability and life insurance.

        STOCK OPTION GRANTS. The following table sets forth certain information
concerning grants of stock options to the named executive officers during the
fiscal year ended December 31, 1997.


                                      -6-
<PAGE>   10


                              OPTION GRANTS IN 1997

<TABLE>
<CAPTION>
                                                                           POTENTIAL REALIZABLE VALUE
                      NUMBER        PERCENT OF                             AT ASSUMED RATES OF
                      OF SHARES     TOTAL OPTIONS                          STOCK PRICE APPRECIATION
                      UNDERLYING    GRANTED TO                             FOR OPTION TERM(2)
                      OPTIONS       EMPLOYEES IN   EXERCISE  EXPIRATION    ------------------
NAME                  GRANTED       FISCAL YEAR      PRICE     DATE        5%          10%
- ----                  -------       -----------      -----     ----        --          ---
<S>                   <C>           <C>            <C>       <C>         <C>         <C>
Michael L. Berman     682,682(1)      49.2%          $.13     1/6/07     $55,814     $141,443

Robert J. Lanham      227,561(1)      16.4%          $.13     1/6/07     $18,605      $47,147
</TABLE>

(1) Consists of options to purchase shares of Common Stock that vested in equal
    monthly installments of 1/12th of the total grant beginning on the grant
    date.

(2) Amounts represent hypothetical gains that could be achieved if the option
    were to be exercised at the end of the option term. The gains are based on
    assumed rates of stock appreciation of 5% and 10%, compounded annually from
    the date the option was granted to the expiration date. Actual gains, if
    any, on stock option exercises will depend on the future performance of the
    Common Stock and the date on which the option, or any portion thereof, is
    exercised.

        YEAR-END STOCK OPTION VALUES. The following table sets forth certain
information concerning stock option exercises and year-end stock option values
for each of the named executive officers for the fiscal year ended December 31,
1997.

       AGGREGATE OPTION EXERCISES IN 1997 AND YEAR-END STOCK OPTION VALUES

<TABLE>
<CAPTION>
                                         NUMBER OF SHARES
                   SHARES                UNDERLYING UNEXERCISED        VALUE OF UNEXERCISED IN-THE-
                   ACQUIRED              OPTIONS AT YEAR-END           MONEY OPTIONS AT YEAR-END(1)
                   ON        VALUE       -------------------           ----------------------------
NAME               EXERCISE  REALIZED  EXERCISABLE   UNEXERCISABLE  EXERCISABLE        UNEXERCISABLE
- ----               --------  --------  -----------   -------------  -----------        -------------
<S>                <C>       <C>       <C>           <C>            <C>                <C>
Michael L. Berman    0         -         782,682          0              0                  0

Robert J. Lanham     0         -         314,234          0              0                  0
</TABLE>

(1) All options have an exercise price that exceeds the market price.

EMPLOYMENT AGREEMENTS

        Neither of the named executive officers currently have employment
agreements with the Company.

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION.

        The Board of Directors as a whole is responsible for determining the
compensation payable to the chief executive officer and to other executive
officers of the Company. When the Board gives


                                      -7-
<PAGE>   11


consideration to the compensation of an executive officer who also is a
director, that director does not participate in the Board's deliberations.

        During 1997, Dr. Goldstein was employed by the Company as its chief
science advisor at an annual rate of $36,000. In May 1994, the Company extended
a loan in the amount of $149,000 to Dr. Goldstein, the Company's Chairman of the
Board, for the purpose of enabling Dr. Goldstein to meet a margin call on a
brokerage account collateralized by the Common Stock of the Company at a time
when the Board of Directors concluded that it would be contrary to the best
interests of the Company for Dr. Goldstein to effect a sale of the shares. The
loan was unsecured and had an interest rate equal to the prime rate, with all
principal and interest due on the December 31, 1994 maturity date. The loan was
repaid on January 1, 1995, in part with the proceeds of a second loan to Dr.
Goldstein from the Company in the amount of $115,617 that was unsecured. The
second loan has an interest rate of 11.5% and was to be repaid in 36 equal
monthly installments. In February 1996, the terms of the loan were amended to
provide for the suspension of installment payments for 12 months, but with
interest continuing to accrue. In March 1997 and December 1997, the terms of the
loan were further amended to suspend installment payments an additional nine and
twelve months, respectively, with interest continuing to accrue. Currently,
installment payments are suspended until December 1998, at which time the loan
will be repayable in 12 equal monthly installments. The highest outstanding
balance on the loan during 1997 was on December 31, 1997, when a balance
consisting of aggregate principal and accrued interest totaled $102,143.

During the period March through June 1997, the Company completed a private
placement of Units in which it sold a total of five Units to seven purchasers,
at a sale price of $50,000 per Unit. Each Unit consisted of (i) 500,000 shares
of Common Stock and (ii) 165,000 Class D Warrants, each of which is exercisable
to purchase one share of Common Stock at an exercise price of $0.10 per share.
Mr. McNay purchased one Unit; Dr. Berman purchased .065 of a Unit; and Mr.
Lanham purchased .05 of a Unit, in each case on the same terms as the purchasers
who were not affiliated with the Company.

REPORT ON EXECUTIVE COMPENSATION.

        The objective of the Board of Directors is to provide compensation
arrangements for the Company's executive officers that generally are competitive
within the industry and that promote the Company's goal of enhancing shareholder
value. The components of the Company's compensation arrangements for its
executive officers consist of base salary, bonuses and stock options.

        BASE SALARY. The base salaries of executive officers are established by
contract or otherwise at levels that the Board (based on the advice of the chief
executive officer as to officers other than the chief executive officer)
believes are necessary to attract and retain executives of a caliber essential
to the Company's success. Because of the few number of persons employed by the
Company, salary levels of executive officers currently are set based on
individual circumstances and not on the basis of an objective formula. While the
Board is aware of the salaries paid to executives at comparable levels of
responsibility by companies of a similar size, including some of the companies
that are included in the NASDAQ Pharmaceutical Stocks Index shown on the Stock
Performance Graph, its executive compensation decisions in 1997 were not
significantly influenced by the competitive environment. Adjustments to salary
levels are made from time to time based upon the foregoing factors and after
giving consideration to the individual performance factors.


                                      -8-
<PAGE>   12


        BONUS. Although the Company does not have an established bonus plan,
individual bonuses are paid to executive officers as provided for under the
terms of individual employment agreements or are awarded from time to time in
recognition of a particular contribution or achievement of an executive officer.
The principal factors taken into consideration in determining bonus awards are
the contributions made by the individual to the achievement of the Company's
product development and financial goals. Bonuses paid to executive officers
other than the chief executive officer usually are determined by the chief
executive officer in consultation with the Board of Directors. No bonuses were
paid to executive officers in 1997.

        STOCK OPTIONS. Because the Company to date has realized only limited
revenues from operations and seeks to maximize the resources available to devote
to product development, the Board has placed significant emphasis on stock
option awards as a non-cash means of executive compensation. Under the Company's
stock option plans, options are awarded at an exercise price equal to the fair
market value of the Common Stock on the date of the grant and generally become
exercisable over a period of years, thereby aligning the compensation realizable
by executives with increases in shareholder value. The size of individual awards
is based on a combination of factors, with a principal emphasis on salary
levels, but with consideration also given to the number of vested and unvested
stock options previously awarded to the executive officer and individual
performance criteria. In 1997, in order to retain and motivate the present
staff, stock options were awarded to Dr. Berman and Mr. Lanham. See "Executive
Compensation -- Stock Option Grants."

        COMPENSATION OF THE CHIEF EXECUTIVE OFFICER. In 1997, a salary of
$149,820 was paid to Dr. Michael L. Berman, the Company's President and Chief
Executive Officer. The Compensation Committee determined that this was the
minimum salary necessary to retain Dr. Berman taking into account the Company's
limited financial resources and the prospects of the Company. The Committee made
no attempt to correlate his salary with any specific quantitative or
quantitative measures of the Company's financial performance or its performance
relative to any other company or group of companies. In order to retain the
services of Dr. Berman, the Committee also granted to him stock options as
reflected in the above table captioned "Option Grants in 1997."

        COMPLIANCE WITH INTERNAL REVENUE CODE SECTION 162(m). Internal Revenue
Code section 162(m), enacted in 1993, prohibits a public company from taking a
deduction for compensation in excess of $1 million paid to its chief executive
officer and any of its other named executive officers. Certain performance-based
compensation, however, is specifically exempted from the deduction limit. No
formal policy has been adopted by the Company with respect to qualifying
compensation paid to its executive officers from the deduction limit. The
Company does not anticipate that any compensation paid to its executive officers
in 1998 will exceed the dollar limit.

                                                Allan L. Goldstein, Chairman
                                                Michael L. Berman
                                                Joseph C. McNay
                                                Albert Rosenfeld


                                      -9-
<PAGE>   13


STOCK PERFORMANCE GRAPH

        The following graph compares the cumulative total stockholder return on
the Common Stock (consisting solely of stock price performance, there having
been no dividends paid during the period) for the last five years with the
cumulative total return (including the reinvestment of all dividends) of (i) the
Standard & Poor's 500 Stock Index and (ii) the NASDAQ Pharmaceutical Stocks
Index. The NASDAQ Pharmaceutical Stocks Index is an industry index of
approximately 276 companies that trade on NASDAQ. The Index is prepared for
NASDAQ by the Center for Research in Security Prices at the University of
Chicago. A list of the companies comprising the Index is available from the
Company upon request. There can be no assurance that the performance of the
Common Stock will continue into the future with the same or similar trends
depicted in the graph below.

<TABLE>
<CAPTION>
                               1992        1993       1994        1995        1996        1997
                               ----        ----       ----        ----        ----        ----
<S>                           <C>         <C>        <C>        <C>         <C>         <C>
Alpha 1                       100.00       93.55       5.04       1.01         .68         .42
S&P 500 Index                 100.00      110.08     111.53     153.45      188.68      251.63
Nasdaq Pharmaceutical         100.00       89.10      67.10     122.70      123.10      127.20
Index
</TABLE>

COMPLIANCE WITH SECTION 16(a) OF THE SECURITIES EXCHANGE ACT

        Section 16(a) of the Securities Exchange Act of 1934, as amended,
requires that each of the Company's directors and executive officers, and any
beneficial owner of more than 10% of the Common Stock, file with the Securities
and Exchange Commission (the "SEC") initial reports of beneficial ownership of
the Common Stock and reports of changes in beneficial ownership of the Common
Stock. Such persons also are required by SEC regulations to furnish the Company
with copies of all such reports. Based solely on its review of the copies of
such reports furnished to the Company for the year ended December 31, 1997, and
on the written representations made by such persons that no other reports were
required, the Company is not aware of any instances of noncompliance with
Section 16(a) during 1997.


                                      -10-
<PAGE>   14


COMMON STOCK OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

        The following table sets forth as of March 20, 1998, unless otherwise
indicated, certain information concerning the beneficial ownership of Common
Stock (i) by each person known by the Company to own beneficially more than 5%
of the outstanding Common Stock, (ii) by each nominee for election as a
director, (iii) by each executive officer of the Company named in the Summary
Compensation Table set forth under the caption "Executive Compensation" and (iv)
by all directors and executive officers of the Company as a group, in each case
as reported to the Company by such persons.

<TABLE>
<CAPTION>
                                                                                PERCENTAGE OF
NAME AND ADDRESS OF                                                             OUTSTANDING
BENEFICIAL OWNER (1)                        NUMBER OF SHARES (2)                SHARES (3)
- --------------------                        -------------------                 --------
<S>                                         <C>                                 <C> 
Allan L. Goldstein                              801,612(4)                          6.4%

Joseph C. McNay                                 791,000(5)                          6.5%

Albert Rosenfeld                                 24,100(6)                           *

Michael L. Berman                               872,132(7)                          6.8%

Robert J. Lanham                                370,461(8)                          3.0%

Roger Samet                                   1,172,050(9)                          9.6%
254 East 68th Street
New York, NY  10021

All directors and executive officers
as a group (five persons)                    2,859,305(10)                         20.6%
</TABLE>

- ---------------------

*  Constitutes less than 1% of the outstanding shares of Common Stock.

(1)     Unless otherwise indicated, the address of the beneficial owner is c/o
        Alpha 1 Biomedicals, Inc., 6707 Democracy Boulevard, Suite 111,
        Bethesda, Maryland 20817.

(2)     A beneficial owner of a security includes a person who directly or
        indirectly has or shares voting or investment power with respect to such
        security. Voting power is the power to vote or direct the voting of the
        security and investment power is the power to dispose or direct the
        disposition of the security. Each person listed has advised the Company
        that, except as otherwise indicted below, such person has, or upon the
        exercise of the stock options or Class D Warrants indicated as
        beneficially owned will have, sole voting power and sole investment
        power with respect to the shares indicated.

(3)     The percentages represent the total number of shares of Common Stock
        shown in the adjacent column divided by the sum of (i) the issued and
        outstanding shares of Common Stock as of


                                      -11-
<PAGE>   15


        March 20, 1998, and (ii) all shares of Common Stock, if any, issuable
        upon the exercise of stock options or Class D Warrants held by such
        person or group that were exercisable on March 20, 1998, or will
        become exercisable within 60 days thereafter.

(4)     Consists of (i) 90,285 shares of Common Stock owned directly by Dr.
        Goldstein and 605,121 shares of Common Stock which he has a right to
        acquire pursuant to the exercise of immediately exercisable options
        granted under the Company's 1986 Incentive Stock Option Plan and 1987
        Non-Qualified Stock Option Plan over which Dr. Goldstein has, or upon
        exercise of such options will have, sole voting and sole investment
        power and (ii) 11,000 shares held in trust for the benefit of Dr.
        Goldstein's daughter, as to which he serves as a co-trustee, 51,103
        shares held by Dr. Goldstein's wife, and 44,103 shares held by Dr.
        Goldstein's wife as custodian for their minor child, all with respect to
        which Dr. Goldstein shares voting and investment power.

(5)     Consists of 612,000 shares of Common Stock owned directly by Mr. McNay
        and 14,000 shares of Common Stock issuable upon the exercise of the
        immediately exercisable portion of options granted under the Company's
        Directors Stock Option Plan and Class D Warrants exercisable to purchase
        165,000 shares of Common Stock.

(6)     Consists of 10,100 shares of Common Stock owned directly by Mr.
        Rosenfeld and 14,000 shares of Common Stock issuable upon the exercise
        of the immediately exercisable portion of options granted under the
        Company's Directors Stock Option Plan.

(7)     Consists of 68,000 shares of Common Stock owned directly by Dr. Berman
        and 782,682 shares issuable upon exercise of immediately exercisable
        stock options granted under the Company's 1986 Incentive Stock Option
        Plan and Non-Qualified Stock Option Plan, and Class D Warrants
        exercisable to purchase 21,450 shares of Common Stock.

(8)     Consists of 54,727 shares of Common Stock owned directly by Mr. Lanham
        and 299,234 shares issuable upon exercise of immediately exercisable
        stock options granted under the Company's 1986 Incentive Stock Option
        Plan and 1987 Non-qualified Stock Option Plan and Class D Warrants
        exercisable to purchase 16,500 shares of Common Stock.

(9)     Consists of 880,000 shares of Common Stock and Class D Warrants
        exercisable to purchase 292,050 shares of Common Stock.

(10)    Consists of 835,112 shares of Common Stock owned directly by all
        directors and executive officers of the Company as a group, the right to
        acquire through the exercise of stock options 1,715,037 shares of Common
        Stock that were exercisable on March 20, 1998, or that will become
        exercisable within 60 days thereafter, 106,206 shares of Common Stock
        owned by wives and children of directors and executive officers, and
        Class D Warrants exercisable to purchase 202,950 shares of Common Stock.


                                      -12-
<PAGE>   16


                     SALE OF THYMOSIN ALPHA 1 ROYALTY RIGHTS

GENERAL


        On December 3, 1997, the Company's Board of Directors unanimously
approved the sale of the Company's royalty rights with respect to Thymosin alpha
1 to SciClone Pharmaceuticals, Inc. in exchange for (i) $130,000 in cash and
(ii) 444,115 shares of SciClone Common Stock (such number of shares being
subject to increase, but not in excess of a total of 600,000, in the event of a
decline in the market price of the SciClone Common Stock, as more fully
described herein). The sale is conditioned on the approval of the transaction by
the Company's stockholders at the Annual Meeting. On March 20, 1998, the market
price of the SciClone Common Stock was $3.25 per share.

        The Company is entering into the SciClone Transaction in order to
generate the cash needed to continue operating as a going concern. If the
SciClone Transaction is approved, it is the Company's current intention to use
the cash proceeds and proceeds from the sale of the SciClone Common Stock to pay
existing indebtedness and to fund current operations while it continues its
efforts to secure additional financing or to effect a business combination.

        In evaluating the SciClone Transaction, stockholders should take into
consideration the fact that the Board of Directors did not obtain from an
outside source either an appraisal of the value of the Thymosin alpha 1 royalty
rights or an opinion as to the fairness of the transaction to the Company and
its stockholders. While the Company did attempt to solicit third-party proposals
to purchase the Thymosin alpha 1 royalty rights, it did not obtain any offers
other than from SciClone.

        The Board's recommendation of the SciClone Transaction to the
stockholders is based on its conclusion that the transaction is superior to any
other alternative available to the Company because it satisfies the Company's
immediate need for cash and should provide the Company with sufficient cash to
continue its operations until approximately the fourth quarter of 1998 assuming
the market price of the SciClone Common Stock remains at or above $3.00 per
share. See "Recommendation of the Board of Directors."

        The sale of the Company's Thymosin alpha 1 royalty rights to SciClone
does not involve an exchange of, or a change in the terms of the outstanding
Common Stock, nor does it require the Company to issue additional shares of the
Common Stock or any other securities. Accordingly, the transaction will not
change the legal rights and preferences of any of the stockholders, each of whom
will continue to hold the same number and percentage of shares that such
stockholder held prior to the transaction. Stockholders do not have appraisal
rights with respect to the transaction.


                                      -13-
<PAGE>   17


BACKGROUND OF THE TRANSACTION

        RELATIONSHIP WITH SCICLONE. From the Company's inception in 1982 through
1994, the Company was primarily engaged in research and development activities
and in the conduct of clinical trials involving Thymosin alpha 1, a 28-amino
acid peptide, for the purpose of evaluating its efficacy in the treatment of
various diseases and immune disorders. In 1990, the Company entered into a
license agreement with SciClone, pursuant to which the Company granted to
SciClone an exclusive license to all of the Company's patent and other
proprietary rights with respect to Thymosin alpha 1 to develop, test, make, use
and sell Thymosin alpha 1 and products containing Thymosin alpha 1 for all human
and animal therapeutic and diagnostic uses (collectively, "Licensed Products").
The original scope of the license covered all countries of the world, with the
exception of the United States, Canada, Israel, Europe and Korea (the "Original
Territory").

        In 1994, as part of the settlement of an arbitration proceeding between
the two companies, the Company entered into a new license agreement with
SciClone (the "SciClone License Agreement") under which the territory covered by
SciClone's exclusive license was expanded to cover the entire world, including
the United States, Canada and Europe, with the exception of Italy, Spain,
Portugal and Korea (the "New Territory"). In 1995, the license granted by the
Company in Korea terminated, with the result that the SciClone License
Agreement, by its terms, extended to cover Korea. In April 1997, Sclavo S.p.A.,
which was the Company's licensee of Thymosin alpha 1 in Italy, Spain and
Portugal, SciClone and the Company entered into agreements whereby (i) Sclavo
relinquished its license from the Company, (ii) SciClone became the exclusive
licensee of the Company in the three countries and (iii) Sclavo became a
sublicensee of SciClone in the three countries. As the result, the Company under
the SciClone License Agreement became entitled to royalties based on Sclavo's
commercial sales in Italy, Spain and Portugal. As a consequence of these
transactions, the New Territory has expanded so that currently the territorial
scope of SciClone's exclusive license is worldwide.

        Under the terms of the Company's SciClone License Agreement, SciClone is
solely responsible for the commercial development of Thymosin alpha 1, including
the conduct of all necessary clinical testing and the securing of all required
regulatory approvals. The Company is entitled to receive a royalty on net sales
revenues from Licensed Product sales in the Original Territory by SciClone and
its sublicensees of (i) 3.5%, if SciClone has patent protection in the country
in which the Licensed Product is sold, and (ii) 3.0%, if SciClone does not have
patent protection. The Company is entitled to receive a royalty on net sales
revenues from Licensed Product sales in the New Territory by SciClone and its
sublicensees of (i) 7.0%, if SciClone has patent protection in the country in
which the Licensed Product is sold, and (ii) 6.0%, if SciClone does not have
patent protection. The Company's right to receive royalties on sales of Licensed
Products continues until September 30, 2002, unless by that date the Company has
not earned royalties of at least $35 million, in which case SciClone's royalty
obligations will continue until the earlier of (i) the receipt by the Company of
royalties totaling $35 million and (ii) September 30, 2009. Under the SciClone
License Agreement, SciClone is responsible for the payment on behalf of the
Company of all royalties due licensors of Thymosin alpha 1 rights to the
Company.

        SciClone has advised the Company that it is currently pursuing the
commercial development of Thymosin alpha 1, under the trademark of Zadaxin(R),
as a treatment of chronic hepatitis B and chronic hepatitis C. According to
SciClone, Zadaxin(R) currently is approved and is being marketed for chronic
hepatitis B in the People's Republic of China, the Philippines and Singapore,
and SciClone has filed for approval to market Zadaxin(R) for this indication in
18 additional countries in Asia, Latin America and the Middle East. In Japan,
SciClone has licensed exclusive rights with respect to Thymosin alpha 1 to the
Japanese subsidiary of Schering-Plough Corporation ("SPKK") which currently is
conducting clinical


                                      -14-
<PAGE>   18


studies. Recently, SciClone announced that SPKK has been authorized by the
Japanese Ministry of Health and Welfare to initiate a pivotal Phase III
hepatitis B study. In Taiwan, SciClone currently is completing various
regulatory filings that will allow SciClone to file for registration. With
respect to use of Zadaxin(R) as a therapy for chronic hepatitis C, SciClone
currently is performing clinical studies in Japan, the United States and Europe.
In the United States and Europe, SciClone is developing Zadaxin(R) in
combination with interferon for the treatment of chronic hepatitis C and is
currently exploring collaborative arrangements for the development and marketing
of Zadaxin(R).

        The following table sets forth the royalties paid to the Company as the
result of sales by SciClone and its sublicensees of Licensed Products.

<TABLE>
<CAPTION>
               Year                                Royalties
               ----                                ---------
               <S>                                 <C>
               1995                                $   4,902
               1996                                $  17,243
               1997                                $  69,104
               1998                                $   2,515*
</TABLE>

*  through March 20, 1998

        In August 1996, the Company entered into an agreement with SciClone
under which the Company received advance royalty payments totaling $500,000. In
exchange, the Company agreed that after receiving royalty payments of $1.75
million, it will forego future royalties, if and when earned, in an amount equal
to $2.5 million (the "First Royalty Prepayment"). In September 1997, the Company
entered into a second agreement with SciClone under which it received an advance
royalty payment of $70,000. In exchange, the Company agreed that after receiving
royalty payments of $1.75 million, it will forego future royalties, if and when
earned, in an amount equal to $700,000 (the "Second Royalty Prepayment"). The
Company entered into both of these transactions in order to obtain funds needed
to continue operations.

        Under the SciClone License Agreement, the decision whether to continue
the commercial development of Thymosin alpha 1 is within the sole discretion of
SciClone. While the Company understands that SciClone is continuing with its
efforts to commercialize Thymosin alpha 1 and has announced receipt of licenses
to market Thymosin alpha 1 in several countries, there is no assurance as to the
extent that the product will be successfully commercialized or as to the amount
of the royalty payments that the Company would receive based on the commercial
sales of Licensed Products by SciClone and its sublicensees.

        EFFORTS TO SELL THYMOSIN ALPHA 1 ROYALTY RIGHTS. Due to the financial
condition of the Company and the status of its product development efforts, the
Company, over its history, has continually required infusions of additional cash
in order to remain a going concern. See "Reasons for the Transaction." One
source of potential revenue has been its right to receive royalty payments on
the commercial sale by SciClone and its sublicensees of Licensed Products.
Through December 31, 1997, the Company has received royalty payments totaling
$91,249, excluding the two advance royalty payments. In addition, the Company
has utilized these assets as a source of cash in the form of the two advance
royalty payments. 


                                      -15-
<PAGE>   19


        In April 1997, Dr. Michael Berman, President and CEO of the Company,
contacted Aurora Capital, a financial advisory company, to discuss possible
means by which the Company could realize immediate value from its Thymosin alpha
1 royalty rights. Following discussions with Aurora, Dr. Berman contacted Don
Sellers, President and CEO of SciClone, to explore the possibility of a sale of
the Thymosin alpha 1 royalty rights to SciClone. This discussion led to a
meeting on May 7, 1997, between Dr. Berman and Mr. Shawn Singh, Vice President
for Business Development of SciClone. Mr. Singh indicated that SciClone was
interested in a transaction that would involve an assignment to SciClone of all
of the Company's patents and licenses for Thymosin alpha 1 in exchange for cash
and shares of SciClone Common Stock.

        On May 15, 1997, Dr. Berman met with Mr. Singh to discuss further
details of a possible transaction. The parties discussed a net present value
analysis prepared by the Company. See "Recommendation of the Board of
Directors." Mr. Singh indicated that the SciClone offer, which was less than the
value of the Thymosin alpha 1 royalty rights suggested by the Company's
analysis, was justified because of the potential appreciation of value of
SciClone Common Stock. Mr. Singh also indicated that, as an added value,
SciClone might be able to provide cash payments to the Company in advance of
stockholder approval, as well as bridge financing to the Company until the
registration statement for the resale of the SciClone Common Stock became
effective.

        On May 23, 1997, Dr. Berman reported to the Company's Board of Directors
on the status of the negotiations with SciClone. Dr. Berman advised the Board
that the parties were still discussing the transaction price, and that he
believed the final price would be between $2 and $3 million. The Board directed
Dr. Berman to continue his negotiations with SciClone and to continue to
investigate any other possible transactions involving the sale of the Thymosin
alpha 1 royalty rights. On June 6, 1997, Dr. Berman met again with Mr. Singh to
continue the negotiations.

        On June 25, 1997, in accordance with the Board's direction, the Company
contracted with The Ulysses Group, a financial advisory company, to conduct a
separate search for potential purchasers of the Thymosin alpha 1 royalty rights.
Through November 1997, the Ulysses Group contacted eleven investment funds or
venture capital funds with regard to a proposal whereby the Company would issue
debentures secured by the Company's Thymosin alpha 1 royalty rights. During the
same period, the Company directly contacted two companies that specialize in
purchasing pharmaceutical and medical product royalty rights, and three other
investment banking companies, regarding the sale of the Thymosin alpha 1 royalty
rights. Three of the companies contacted requested further information about
Thymosin alpha 1 and the royalty rights, but none pursued discussions with the
Company beyond this point. On the basis of these contacts, the Company concluded
that it was unlikely to locate another bidder for the royalty rights within a
timeframe consistent with the Company's immediate need for cash.

        On August 28, 1997, SciClone presented a term sheet to the Company that
outlined SciClone's offer and also made an offer with respect to the Second
Royalty Prepayment. See "Background of the Transaction -- Relationship with
SciClone." On September 4, 1997, the Board met and discussed SciClone proposals.
Due to the Company's need for immediate funding to continue its operations, the
Board approved the Second Royalty Prepayment and instructed Dr. Berman to
continue negotiations with SciClone over the terms of the sale of the Thymosin
alpha 1 royalty rights. Following the Board meeting, SciClone and the Company
continued to exchange drafts of an agreement.

        On December 3, 1997, the Board met and was advised of the final terms of
the proposed agreement. The Board also was advised that despite its efforts, the
Company had been unable to attract any other offers for the royalty stream. The
Board voted unanimously in favor of the final terms of the agreement, which was
signed on December 17, 1997.


                                      -16-
<PAGE>   20


DESCRIPTION OF THE ALPHA RIGHTS ACQUISITION AGREEMENT

        The following is a summary of the material terms of the Alpha Rights
Acquisition Agreement, dated as of December 17, 1997, between the Company and
SciClone (the "Acquisition Agreement"), under which the Company will exchange
its royalty rights with respect to Thymosin alpha 1 for cash and shares of
SciClone Common Stock. This summary is qualified in its entirety by the text of
the Acquisition Agreement, a copy which has been filed by the Company with the
United States Securities Exchange Commission (the "SEC") as Exhibit 10.1 to a
Form 8-K, dated December 17, 1997. A copy of the Acquisition Agreement,
including exhibits, may be obtained upon a written or oral request directed to
Robert J. Lanham, Chief Financial Officer, Alpha 1 Biomedicals, Inc., 6707
Democracy Boulevard, Suite 111, Bethesda, MD 20817-1129, telephone number (301)
564-4400. The Form 8-K is available from the SEC's Electronic Data Gathering and
Retrieval ("EDGAR") database located at the website maintained by the SEC at
http://www.sec.gov.

        ASSETS CONVEYED AND LIABILITIES ASSUMED. Under the terms of the
Acquisition Agreement, Alpha will release SciClone, effective as of December 17,
1997 (the "Effective Date"), from all future royalty obligations to the Company
arising from the sale by SciClone and its sublicensees of Licensed Products. In
addition, the Company will transfer and assign to SciClone (i) all of the
Company's right, title and interest in and to all of the Company's patents and
patent applications (both domestic and foreign) with respect to Thymosin alpha 1
(the "Alpha Owned Patent Rights") and (ii) all of the Company's rights under
licenses with third parties pursuant to which the Company has acquired rights to
Thymosin alpha 1 (the "Alpha Licensed Patent Rights" and, together with the
Alpha Owned Patent Rights, the "Thymosin Alpha 1 Rights"). SciClone will assume
all of the Company's obligations, including royalty obligations, to such
third-party licensors of Alpha Licensed Patent Rights.

        CONSIDERATION RECEIVED BY THE COMPANY. In consideration for
relinquishing its right to future royalties and for conveying the Thymosin Alpha
1 Rights to SciClone, the Company will receive a combination of cash and shares
of SciClone Common Stock as follows:


        Cash. In anticipation of the consummation of the transaction, SciClone
has made cash payments to the Company totaling $130,000. If the transaction does
not close for any reason (including the failure to obtain stockholder approval),
SciClone will be credited with a prepayment of future royalties in an amount
equal to (i) $130,000, minus the amount royalties foregone by the Company on and
after the Effective Date, multiplied by (ii) a factor of ten, with such credit
to take effect after SciClone has made royalty payments to the Company totaling
$1.75 million. The credit received by SciClone against future royalty payments
of ten times the amount of cash received by the Company was the result of
negotiations between the parties and reflects both the risk that such royalties
may never be earned and the discounted present value of any such future
royalties that are earned.


        SciClone Common Stock. On the Closing Date (as hereinafter defined) of
the transaction, the Company will receive 444,115 shares of SciClone Common
Stock (the "Initial Shares"). This number of Shares was calculated by dividing
(i) $1.8 million by (ii) a price per share of SciClone Common Stock of $4.053
(the "Initial Average Price"), representing the average of the closing sale
prices per share of SciClone Common Stock for the 20 trading days immediately
preceding the date that was three trading days prior to the Effective Date.

        The Initial Shares will be subject to resale restrictions, as provided
for in a Stock Rights Agreement between the Company and SciClone to be entered
into at the closing, the form of which attached as Exhibit


                                      -17-
<PAGE>   21


D to the Acquisition Agreement (the "Stock Rights Agreement"). Under the Stock
Rights Agreement, (i) SciClone will agree to file a registration statement (the
"Registration Statement") under the Securities Act of 1933, as amended, that
will register both the Initial Shares and the Additional Shares (as hereinafter
described) for resale by the Company and (ii) the Company will agree that,
commencing with the 30-day period beginning on the effective date of the
Registration Statement and during each of the next eleven 30-day periods
thereafter (each a "Lock-Up Period", and the first day of each such Lock-Up
Period being referred to as a "Lock-Up Release Date"), it will limit its resale
(i) of Initial Shares to a number that is equal to 1/12 of the total number
Initial Shares and (ii) of Additional Shares to a number that is equal to
50,000, minus the number of Initial Shares sold during the Lock-Up Period.

        To compensate the Company if the market price of the SciClone Common
Stock declines below the Initial Average Price over the course of the successive
Lock-Up Periods, SciClone has agreed to issue additional shares of SciClone
Common Stock to the Company under certain circumstances. Whether the Company is
entitled to additional shares of SciClone Common Stock is determined by
computing the average of the assigned value per share of SciClone Common Stock
(the "Average Price") on a particular Lock-Up Release Date and each preceding
Lock-Up Release Date (the assigned value per share for each such Lock-Up Release
Date being equal to the average of the closing sale prices per share for the 20
trading days immediately preceding the date that is three trading days prior to
the applicable Lock-Up Release Date). The average of the assigned values (the
"Average Price") is then compared to the Initial Average Price. If the Average
Price is less than the Initial Average Price, SciClone will issue to the Company
a number of additional shares (the "Additional Shares") which, when added to
applicable fraction of the number of Initial Shares (calculated by multiplying
1/12 of the Initial Shares by the number of Lock-Up Release Dates that have
elapsed) and any Additional Shares issued on prior Lock-Up Release Dates, will
have a value (calculated based on the Average Price) equal to (i) $150,000
multiplied by (ii) the number of Lock-Up Release Dates that have elapsed
(including the then current Lock-Up Release Date); provided that the total
number of Initial Shares and Additional Shares issued to the Company cannot
exceed 600,000. This computation was arrived at by agreement of the parties and
is designed to provide for the issuance to the Company of additional shares of
SciClone Common Stock (subject to the 600,000 share limitation) if the market
price of the SciClone Common Stock declines prior to the time that the Company
is eligible to sell the shares consistent with the lock-up restriction on
resale.

The following table illustrates the value of the SciClone Common Stock that the
Company would receive (taking into account the 600,000 share limitation) under
the terms of the Acquisition Agreement assuming the assigned value of the
SciClone Common Stock on the date of the closing and on each successive Lock-Up
Release Date is as indicated under column headed "SciClone Common Stock Price":

<TABLE>
<CAPTION>
     SciClone            Value of                              Value of           Value of
   Common Stock           Initial          Additional         Additional            Total
       Price            Shares (1)           Shares           Shares (2)         Shares (3)
 ----------------   ------------------  ----------------  -----------------  ------------------
<S>                  <C>                   <C>             <C>                <C>
       $1.00         $      444,115           155,885      $     155,885      $      600,000
       $2.00         $      888,230           155,885      $     311,770      $    1,200,000
       $3.00         $    1,332,345           155,885      $     467,655      $    1,800,000
       $4.00         $    1,776,460             5,880      $      23,520      $    1,800,000
       $5.00         $    2,220,575                 0                  0      $    2,220,575
       $6.00         $    2,664,690                 0                  0      $    2,664,690
</TABLE>


                                      -18-
<PAGE>   22


(1)     Calculated by multiplying 444,115 shares of SciClone Common Stock by the
        applicable SciClone Common Stock Price.

(2)     Calculated by multiplying the number of Additional Shares by the
        applicable SciClone Common Stock Price.

(3)     The sum of the Value of the Initial Shares and the Value of the
        Additional Shares.

        Because the future price of SciClone Common Stock cannot be known,
neither the number of Additional Shares, if any, that the Company would receive,
nor the proceeds that the Company would be able to realize from the sale of the
Initial Shares and the Additional Shares, if any, is determinable.

        The following table sets forth certain historical information concerning
the market price of the SciClone Common Stock:

<TABLE>
<CAPTION>
        1996                    HIGH            LOW
        ----                    ----            ---
        <S>                     <C>             <C>
        1st Quarter             16 1/8           4 3/4
        2nd Quarter             15 1/8          11 1/4
        3rd Quarter             14 3/4           6 7/8
        4th Quarter             13               7 5/8

        1997                    HIGH            LOW
        ----                    ----            ---

        1st Quarter             10               5  1/8
        2nd Quarter              7 1/2           4  3/8
        3rd Quarter              6 1/2           3  7/16
        4th Quarter              7 3/8           2 15/16

        1998                    HIGH            LOW
        ----                    ----            ---

        1st Quarter (through
        March 20, 1998)          3 7/8           1 13/16
</TABLE>

        On March 20, 1998, the closing sale price of the SciClone Common Stock
was $3.25 per share.

        BRIDGE LOAN. To assist the Company in funding its operations pending the
closing of the SciClone Transaction and prior to the effectiveness of the
Registration Statement, SciClone has agreed in the Acquisition Agreement to loan
to the Company up to $280,000 as follows: (i) $70,000 on the sixty-first
calendar day following the Effective Date, (ii) $70,000 on the later of (A) the
ninety-first calendar day following the Effective Date and (B) the first
business day following the closing, and (iii) $70,000 on the business day in
each of the next two months corresponding to the business day of the loan
referred to in clause (ii), if such corresponding business day precedes the
effective date of the Registration Statement (collectively, the "Advances"). The
obligation of the Company to repay the Advances will be evidenced by a
Promissory Note and Security Agreement, the form of which is attached as Exhibit
E to the Acquisition Agreement. Advances are non-interest bearing (except to the
extent that the Company fails to repay any principal installment when due, in
which case the overdue installment will bear interest at the rate of 10% per
annum). The Advances will be secured by Initial Shares having a market value
equal to the principal amount of the Advances. The Company will be required to
repay the Advances in monthly installments of


                                      -19-
<PAGE>   23


$70,000, commencing on the earlier of (i) the ninth Lock-Up Release Date and
(ii) the Lock-Up Release Date following any date on which the Company receives
new equity financing of at least $500,000, and in any event the Advances will be
due and payable in full on May 31, 1999. If the transaction does not close for
any reason, SciClone will be credited with a prepayment of $700,000 in future
royalties (effective after SciClone has made royalty payments to the Company
totaling $1.75 million) with respect to the $70,000 Advance made in anticipation
of the closing, in lieu of the obligation of the Company to repay the Advance.
The credit received by SciClone against future royalty payments of ten times the
amount of the loan proceeds was the result of negotiations between the parties
and reflects both the risk that such royalties may never be earned and the
discounted present value of any such future royalties that are earned, as well
as the benefit to the Company of the interest-free loan.

        CONDITIONS TO THE CLOSING. In addition to approval by the stockholders
of the Company, the SciClone Transaction is conditioned on (i) the consent by
each of F. Hoffmann-LaRoche Ltd. and Hoffmann-LaRoche, Inc. to the assignment to
SciClone of certain Thymosin alpha 1 rights currently licensed to the Company by
the respective companies, (ii) the receipt by the Company of a "no-action
commitment", in a form agreed upon by the Company and SciClone, from the
Company's creditors holding at least 90% of the aggregate dollar amount of the
Company's financial obligations, (iii) the absence of a material adverse event
affecting the rights being conveyed to SciClone that is outside of the control
of SciClone, (iv) the continued accuracy in all material respects of the
representations and warranties of the Company and SciClone contained in the
Acquisition Agreement, (v) the compliance by the Company and SciClone with the
covenants that each is required to perform or comply under the Acquisition
Agreement, and (vi) other customary conditions. Any one or more of the
conditions to the closing can be waived by the party for whose benefit the
condition or conditions is intended. As of March 20, 1998, the Company had
received "no action commitments" from creditors holding 75% of the aggregate
dollar amount of the Company's financial obligations. Management believes the
Company will satisfy all of the conditions necessary for closing in a timely
manner that will not unduly delay the closing.


        CLOSING. The closing of the transaction (the "Closing") will occur on a
date (the "Closing Date") that is within five business days after all of the
conditions to the Closing have been satisfied or waived or on such later date as
the Company and SciClone shall agree.

        ASSUMED AND RETAINED LIABILITIES. From and after the Closing, SciClone
will assume all of the liabilities of the Company, and will agree to perform all
of the covenants and agreements of the Company, with respect to the Thymosin
Alpha 1 Rights that accrue as of and after the Closing (the "Assumed
Liabilities"). From and after the Closing, the Company will continue to be
responsible for all of the liabilities of the Company, and will be obligated to
perform all of the covenants and agreements of the Company, with respect to
Thymosin alpha 1 accrued as of the Closing, but excluding all of the liabilities
that SciClone agreed to perform under the SciClone License Agreement (the
"Retained Liabilities"). Those obligations of SciClone that are excluded from
Retained Liabilities include SciClone's obligations under the SciClone License
Agreement to pay on behalf of the Company all royalties due licensors to the
Company based on SciClone's sales of Licensed Products.

        REPRESENTATIONS AND WARRANTIES. The Acquisition Agreement contains
customary representations and warranties made by the Company and by SciClone.
Among the representations and warranties of the Company are those concerning (i)
the absence of any undisclosed legal proceedings against the Company involving
the Thymosin Alpha 1 Rights, (ii) compliance by the Company in all material
respects with all laws and regulations with respect to or affecting the Thymosin
Alpha 1 Rights, (iii) the enforceability and the absence of any breaches of the
agreements pursuant to which the Company holds the Alpha Licensed Patent Rights,
(iv) the absence of any rights granted by the Company to third


                                      -20-
<PAGE>   24


parties with respect to the Thymosin Alpha 1 Rights, and (v) the absence of any
claims against the Company with respect to the Thymosin Alpha 1 Rights. All of
the representations and warranties of both parties will survive the Closing.

        INDEMNIFICATION. The Company is obligated to indemnify SciClone for: (i)
losses, expenses and liabilities incurred by SciClone as the result of any
breach by the Company of its representations and warranties or the failure of
the Company to perform any of its obligations under the Acquisition Agreement
and related agreements, and (ii) all liabilities, obligations and claims arising
prior to the Closing Date with respect to the Retained Liabilities. SciClone is
obligated to indemnify the Company for: (i) losses, expenses and liabilities
incurred by SciClone as the result of any breach by SciClone of its
representations and warranties or the failure of SciClone to perform any of its
obligations under the Acquisition Agreement and related agreements, and (ii)
liabilities, obligations and claims arising from and after the Closing Date with
respect to the Assumed Liabilities. The indemnification obligations for breaches
of representation and warranty and for breaches of covenant apply only to claims
asserted within a three-year period following the Closing Date.

        COVENANT NOT TO COMPETE. In the Acquisition Agreement, the Company
agrees that it will not, directly or indirectly, make, have made, use or sell
Thymosin alpha 1 anywhere in the world. This restriction remains in effect for
so long as SciClone has patent rights with respect to Thymosin alpha 1 in any
country.

        TERMINATION. The Acquisition Agreement may be terminated by either party
if such party is not in default of its obligations under the Acquisition
Agreement and either (i) the Closing has not occurred by April 30, 1998 (whether
or not the stockholders of the Company have approved the transaction) or (ii)
the stockholders of the Company fail to approve the transaction.

        TERMINATION OF SCICLONE LICENSE AGREEMENT. At the time of the Closing,
the SciClone License Agreement will terminate, except for certain provisions,
including provisions relating to the following matters, that will remain in full
force and effect: (i) SciClone's royalty and reporting obligations prior to the
Closing to the licensors to the Company of the Thymosin alpha 1 rights
sublicensed by the Company to SciClone, (ii) the restrictions on the purchase by
SciClone of shares of Alpha Common Stock, and (iii) the indemnification
obligations of both the Company and SciClone.

REASONS FOR THE TRANSACTION

        At the current time, the Company has no technology that appears to offer
a reasonable prospect for commercial success within the near term. After the
licensing of Thymosin alpha 1 to SciClone, the Company's remaining technology
has been limited to Thymosin beta 4, a 43-amino acid peptide. However, the
commercial development of Thymosin beta 4 for the treatment of cystic fibrosis,
the most promising indication for which Thymosin beta 4 has been identified as a
possible treatment, cannot be pursued without the risk of infringing an issued
U.S. patent held by another company. Very limited preclinical testing of
Thymosin beta 4 in animals for other indications has produced only mixed
results. Even if Thymosin beta 4 were to show indications of efficacy in the
treatment of a particular disease or condition, commercialization would require
many years of testing and significant financial resources. In view of this
situation, the Board of Directors has concluded that absent the acquisition of
new technology, coupled with substantial financing, the Company will be unable
to survive as an independent entity.

        The Company is proposing to enter into the SciClone Transaction in order
to generate the cash needed to continue operating as a going concern, including
the payment of existing indebtedness. In


                                      -21-
<PAGE>   25


approving the transaction, the Board of Directors determined there was no other
transaction available to the Company that would satisfy the Company's immediate
cash needs while the Company continues its efforts to secure additional
financing to fund the acquisition of new technology or to effect a business
combination with a company having cash resources or a financeable technology. In
this regard, on March 4, 1998, the Company entered into an agreement with Aurora
Capital Corporation pursuant to which Aurora will provide the Company with
advisory and investment banking services, including the identification of
potential merger or acquisition candidates and analysis of possible deal
structures. However, there is no assurance that the Company's efforts, or those
on behalf of the Company by Aurora, will be successful.

        PRODUCT DEVELOPMENT EFFORTS. Since its inception in 1982, the Company's
primary activities have consisted of research and development and the conduct of
clinical trials involving several peptides to which the Company has held
proprietary rights. These efforts have met with only limited success.

        Through mid-1994, the primary focus of the Company was on efforts to
commercialize Thymosin alpha 1 as a treatment for various disease indications or
as a vaccine adjuvant. The Company's resources were devoted primarily to an
evaluation of Thymosin alpha 1 as a treatment for chronic hepatitis B. In April
1994, the results of a Phase III multicenter clinical trial sponsored by the
Company to test Thymosin alpha 1 as a treatment for this indication were
analyzed. The results did not show a statistically significant difference
between the response of the treatment group and the placebo group. This led the
Company to conclude that, without further testing, the results of the Phase III
trial would not support the submission of a New Drug Application (an "NDA") to
the U.S. Food and Drug Administration for approval of Thymosin alpha 1 as a sole
treatment for chronic hepatitis B. The further testing needed to support an NDA
would have required a commitment of resources beyond the Company's financial
capacity. As a result, in August 1994, the Company, as part of the settlement of
an arbitration proceeding between the Company and SciClone, entered into the
SciClone License Agreement under which it licensed to SciClone the worldwide
rights to Thymosin alpha 1. See "Background of the Transaction -- Relationship
with SciClone." Shortly thereafter, the Company's research facilities in
California were closed and the total number of employees was reduced from 29 to
5.

        After licensing of Thymosin alpha 1 to SciClone, the Company refocused
its research and development efforts on an evaluation of the prospects for
commercialization of Thymosin beta 4. However, initial efforts to develop
Thymosin beta 4 as a treatment for cystic fibrosis were discontinued in February
1996 when the Company learned of an issued United States patent on which the
sale of Thymosin beta 4 as a treatment for cystic fibrosis would probably
infringe. Efforts to obtain a license to this patent have been unsuccessful. In
1997, an animal study conducted by an investigator at Vanderbilt University to
evaluate the potential of Thymosin beta 4 to treat septic shock did not produce
a positive result. More recently, the Company in a collaboration with
investigators at the National Institutes of Health has obtained encouraging, but
very preliminary results, using Thymosin beta 4 in the areas of angiogenesis and
skin growth.

        In February 1996, the Board of Directors of the Company, due to the
financial circumstances of the Company, approved a plan which provided for the
reduction or termination of all ongoing research and development activities, a
reduction in leased space, a reduction in certain salaries and the severance of
administrative staff. Pursuant to this plan, the Company relocated its
headquarters to a smaller space and currently has 3 full-time employees. Since
that time, no further development and only limited research has been conducted
by the Company.

        In connection with its Thymosin beta 4 research and development
activities, the Company entered into contracts with several vendors to provide
various products and services. When the Company substantially discontinued its
research and development activities in 1996, these contracts were terminated,


                                      -22-
<PAGE>   26


leaving the Company with payments due four vendors (the "Vendors") totaling $1.3
million. In 1996, the Company entered into agreements with each of the Vendors
under which these obligations would be paid with the proceeds of royalty
payments received by the Company under the SciClone License Agreement.


        CURRENT FINANCIAL SITUATION. Since its inception, the Company's
operations have been funded by the proceeds from the issuance of equity
securities (and interest earned on such funds), the licensing of technology
developed or acquired by the Company, and limited product sales. Through
December 31, 1997, the Company had an accumulated deficit of $38.1 million.

        At December 31, 1997, the Company had total liabilities of $2.2 million,
including the $1.3 million due the Vendors, and current assets of $68,000, of
which $21,000 consisted of cash and cash equivalents. These amounts include a
cash payment of $65,000 received by the Company in December 1997 from SciClone
under the Acquisition Agreement. In January and February 1998, the Company 
received $135,000 from SciClone under the Acquisition Agreement.  These
proceeds are being used to fund current operations and to pay legal, accounting
and other expenses associated with the SciClone Transaction. The Company
estimates that its existing cash will be sufficient to sustain the Company's
operations to the second quarter of 1998.  In the event shareholder approval is
not received, after the Company has been paid $1.75 million in royalties,
royalty payments from SciClone will not resume until SciClone effects sales of
Licensed Products sufficient to generate cumulative royalties in excess of
$6.95 million. After the royalty payments resume, the Company is entitled to
receive additional royalty payments up to $28.05 million.

        Because the Company is required to make the payment due the Vendors from
the proceeds of royalties payments received by SciClone, the SciClone
Transaction will have the effect of accelerating the payments due the Vendors.
In consideration for the acceleration of payments, the Vendors have agreed to
reduce the Company's aggregate obligation to $902,000 which the Company has
committed to pay from the proceeds of the sale of the shares of SciClone Common
Stock received in the SciClone Transaction.

        If the SciClone Transaction is approved by stockholders and the
transaction closes, the Company will receive, as of the closing, the 444,115
Initial Shares as provided for under the Acquisition Agreement. Under the terms
of the Stock Rights Agreement, these shares may be sold by the Company over a
period of 12 months following the effectiveness of the Registration Statement.
After the closing and prior to the effectiveness of the Registration Statement,
SciClone is obligated to advance to the Company the remaining three installments
of the Bridge Loan in the amount of $70,000 per month increasing the total
amount of the Bridge Loan to $280,000. This amount is subject to repayment by
the Company under the terms of the Promissory Note and Security Agreement. See
"Description of the Alpha Rights Acquisition Agreement -- Bridge Loan."

        On March 20, 1998, the closing market price of the SciClone Common Stock
was $3.25 per share. If the market price of the SciClone Common Stock remains at
this price, the number of Initial Shares and any Additional Shares that the
Company is eligible to sell each month will generate gross proceeds (before
brokerage commissions) of approximately $150,000 per month. From these proceeds,
the Company will be obligated to make payments of approximately $100,000 per
month to discharge preexisting financial obligations, including the payments due
the Vendors and will be obligated to repay the Bridge Loan. The remainder will
be available to fund ongoing operations.

        FUTURE PROSPECTS. The Company has not generated significant revenues
from operations and does not anticipate generating product revenues for the
foreseeable future. The Company will require substantial funding in order to
acquire new technology, to resume and conduct its research and development
activities, and to manufacture and market any product that might be developed.


                                      -23-
<PAGE>   27


        If the SciClone Transaction is completed, the Company's sole source of
cash, absent a new financing, will be the sale of the SciClone Common Stock.
Based on its current cash flow projections, the Company believes that the
proceeds from the SciClone Transaction will provide it with sufficient funds to
continue as a going concern into the fourth quarter of 1998. This projection is
dependent upon the price of the SciClone Common Stock remaining at or above
$3.00 per share. Should the price of SciClone Common Stock decline below that
price or should unforeseen financial needs arise, the period for which the
Company should be able to continue in operation using the proceeds of the
SciClone Transaction would be shortened.

        During this future period, the Company has no plan to engage in any
product development activities. It expects that its efforts will be directed
exclusively to pursuing (i) a financing the proceeds of which would be used to
acquire one or more new technologies and resume research and development
activities or (ii) a business combination with a company that has existing cash
resources or a financeable technology. The Company expects to pursue each of
these objectives; however, there is no assurance that the Company will be
successful in its efforts.

RECOMMENDATION OF THE BOARD OF DIRECTORS

        The Board of Directors believes that the proposed transaction with
SciClone is in the best interests of the Company's stockholders. Accordingly, by
a unanimous vote, the Board of Directors has approved the Acquisition Agreement
and recommends that the Company's stockholders vote to approve the SciClone
Transaction.

        In its deliberations concerning the Acquisition Agreement, the Board of
Directors focused on the following factors: (i) the financial condition of the
Company, (ii) the limited commercial prospects of the Company's existing
technology, and (iii) the inability of the Company to locate any other entity
willing to purchase the remaining Thymosin alpha 1 royalty rights. The Board of
Directors did not assign particular weight to any one of the factors, nor did it
assign relative weights or ranking to the factors. Rather, the Board concluded
that in view of the Company's financial condition and its prospects, the
transaction with SciClone is superior to any other option available to the
Company.

        In order to evaluate the SciClone offer, the Company prepared an
estimate of the net present value of a projected future royalty stream from
SciClone's sales of Thymosin alpha 1. Neither in its negotiations with SciClone
over the sale of the Thymosin alpha 1 royalty rights nor at any other time has
the Company received from SciClone any nonpublic projections of future sales of
Licensed Products. However, the Company was aware of a research report on
SciClone published by Everen Securities in May 1997 (the "Everen Report"). From
the projections set forth in the Everen Report, the Company estimated the
revenues of SciClone from the sale of Zadaxin(R) in the Original Territory and
the New Territory would be as follows:


<TABLE>
<CAPTION>
                      ORIGINAL TERRITORY           NEW TERRITORY
                      ------------------           -------------
                         (IN MILLIONS)             (IN MILLIONS)
<S>                   <C>                          <C>
        1997          $     4.0                    $       0
        1998                9.8                            0
        1999               15.9                            0
        2000               22.0                            0
        2001               37.7                           55.2
        2002               65.0                          110.4
</TABLE>


                                      -24-
<PAGE>   28


        Beyond 2002, the Company's analysis assumed that SciClone's revenues in
both the Original Territory and the New Territory would remain at the 2002
levels. The Company also assumed an average royalty rate of 3.25% in the
Original Territory and 6.25% in the New Territory. See "Background of the
Transaction -- Relationship with SciClone." To calculate a net present value of
the estimated royalty stream in the Original Territory, the Company applied a
discount rate of 35%. In the New Territory, the Company computed the net present
value of the royalty stream using alternatively a 35% discount rate and a 70%
discount rate. The choice of these discount rates reflect the relative
uncertainty of future market conditions, regulatory approvals and other
unforeseen circumstances. Applying this analysis, the Company concluded that the
net present value of the Company's future royalties from projected Zadaxin(R)
sales (after taking account of the $2.5 million effect of the First Royalty
Prepayment, but not the $700,000 effect of the Second Royalty Prepayment) was
(i) $6.3 million using the discount rate of 35% in the New Territory and (ii)
$3.4 million using the discount rate of 70% in the New Territory.
Notwithstanding this valuation analysis, the Company was unable either to
improve the SciClone proposal over the terms provided for in the Acquisition
Agreement or to attract an alternative bidder.

        The Board of Directors did not obtain an independent valuation of the
Thymosin alpha 1 royalty rights nor did it engage an investment banking firm or
other professional entity to render an opinion as to the fairness of the
transaction to the Company and its stockholders. In the view of the Board, the
costs of such a valuation or fairness opinion would have been prohibitive and,
given the absence of any competing bidders, may not, in any event, have secured
more favorable terms.

        In its deliberations, the Board of Directors also recognized that,
although the provisions of the Acquisition Agreement are designed to compensate
the Company for a possible decline in the market price of the SciClone Common
Stock through the issuance of Additional Shares, because of the 600,000 share
limitation on the total number of Initial Shares and Additional Shares issuable,
the value, as of the date of the Acquisition Agreement, of the shares to be
received by the Company is not protected if, over the course of the Lock-Up
Release Dates, the Average Price decreases and remains below $3.00. See
"Description of the Alpha Rights Acquisition Agreement -- Consideration Received
by the Company." However, efforts to remove the share limitation through
negotiation were unsuccessful.

        Among the alternatives to the SciClone Transaction that were considered
by the Board of Directors was a business combination with a better capitalized
company or a company with a financeable technology. Although the Company has
been aggressive in its efforts to identify such a company and has engaged in
discussions with several such companies, its efforts to date have been
unsuccessful. Although such discussions with a privately-held company that would
be merged into the Company were ongoing in late 1997, there have been no
discussions with the company since that time. The Board has concluded that the
financial condition of the Company would not permit it to delay the SciClone
Transaction while the search for a business combination candidate continues. The
Board does not believe that the SciClone transaction will impair the prospects
for a successful business combination if a suitable candidate can be located.

        The Board of Directors also considered continuing to receive royalties
under the SciClone License Agreement as an alternative to the SciClone
Transaction. However, this alternative was rejected because the amount of such
royalties was uncertain and in any event, at least in the near term, would be
insufficient to enable the Company to meet its financial obligations and to
sustain operations.

        Finally, the Board of Directors considered a possible liquidation of the
Company in which the proceeds of the SciClone Transaction would be distributed
to stockholders, rather than used to fund the Company's continuing operations.
However, the Board concluded that, after discharging the Company's liabilities
and the payment of the administrative expenses associated with a liquidation,
there would be little


                                      -25-
<PAGE>   29


or no funds available for distribution to the stockholders. On this basis, the
Board concluded that a liquidation would not be in the best interests of the
stockholders.

FEDERAL INCOME TAX CONSEQUENCES

        The following is a description of the material federal income
consequences of the SciClone Transaction. This discussion is a general and
abbreviated summary, based on interpretations of existing sources of law. This
discussion does not address any state, local, or foreign tax consequences or any
federal tax consequences other than those relating to the income tax.

        The Company has not obtained an opinion of tax counsel regarding the tax
treatment of the SciClone Transaction. The Company is not requesting a ruling
from the Internal Revenue Service regarding the tax consequences of the SciClone
Transaction, and there is no assurance that the Internal Revenue Service will
follow the interpretations set out below.

        The SciClone Transaction should be treated for U.S. federal income tax
purposes as a cancellation of the SciClone License Agreement and a sale by the
Company to SciClone of the Alpha Owned Patent Rights, the Alpha Licensed Patent
Rights (in conjunction with SciClone's assumption of the future liabilities
thereunder), and the covenant not to compete (the "Assets") in exchange for
$130,000 in cash, the Initial Shares, any Additional Shares, and possibly an
amount representing imputed interest on the (up to) $280,000 of Advances (the
"Proceeds"). As a result, the Company would recognize gain (or loss) on each of
the Assets measured by the difference between the Company's basis in each Asset
and the portion of the fair market value of the Proceeds allocable to that
Asset. The Proceeds should be allocable among the Assets in proportion to the
fair market values of the Assets. The Company generally has no more than a
nominal basis in any of the Assets.

        To the extent that the Assets constitute capital assets, the Company
would recognize capital gain (or loss) on the sale, subject to the recapture
rules of Section 1245 of the Internal Revenue Code (the "Code"). Under Section
1245 of the Code, a portion of the gain from the sale of capital assets may be
treated as ordinary income. To the extent that the Assets are other than capital
assets, the Company would recognize ordinary income (or loss), subject to the
provisions of Section 1231 of the Code. Section 1231 of the Code, in certain
circumstances and subject to a number of restrictions, treats as capital gain
certain gain that otherwise would be taxed as ordinary income.

        The Company may offset gain recognized on the sale of the Assets by
other losses, including net operating loss carryforwards that the Company
currently has available. The Company currently has sufficient net operating loss
carryforwards to offset any gains, capital or ordinary, that the Company would
realize on the sale of the Assets.

        The Company's subsequent sale of Initial Shares or Additional Shares
received as part of the Proceeds would give rise to gain or loss measured by the
difference between the amount received for such Shares and the Company's basis
in those shares. The Company's basis in the Initial Shares and Additional Shares
should be the fair market value of the respective shares on the day they are
issued to the Company.

        Because the SciClone Transaction does not involve an exchange of, or
change in the terms of, the outstanding shares of Common Stock, it should have
no federal income consequences for the Company's stockholders themselves.
However, stockholders having specific questions regarding the impact of the
SciClone Transaction should consult their own tax advisors.


                                      -26-
<PAGE>   30


ACCOUNTING TREATMENT

The accounting treatment described below for the SciClone Transaction is based
in part on APB Opinion No. 29, "Accounting for Nonmonetary Transactions," and
Statement of Financial Accounting Standards No. 115, "Accounting for Certain
Investments in Debt and Equity Securities".

Gain on SciClone Transaction. The Company will account for the SciClone
Transaction based upon the fair value of the consideration received, which is
more readily determinable than the fair value of the Company's right to receive
royalty payments from the future sales by SciClone and its licensees of Thymosin
alpha 1. The Company will record at the Closing Date a gain on the SciClone
Transaction in the amount as the sum of (i) $130,000 of cash received, (ii) the
fair market value of the 444,115 Initial Shares received, determined by
reference to the closing market price per share of SciClone Common Stock at the
Closing Date as reported by the Nasdaq Stock Market, and (iii) the intrinsic
value of the Company's right to receive Additional Shares of SciClone Common
Stock, subject to a maximum of 155,885 Additional Shares, if the market value of
SciClone Common Stock is below $4.053 per share during the Lock-Up Periods. The
intrinsic value, which approximates fair market value, of the right to receive
Additional Shares of SciClone Common Stock will be determined by reference to
the closing market price per share of SciClone Common Stock at the Closing Date
as reported by the Nasdaq Stock Market. Because the future price of the SciClone
Common Stock cannot be known, the gain on the SciClone Transaction is
indeterminable at this time.

Subsequent Accounting for SciClone Common Stock. Subsequent to the Closing Date,
the Company will classify the SciClone Common Stock as available-for-sale for
financial reporting purposes. To the extent that the subsequent market value of
the SciClone Common Stock is above or below the market value on the Closing
Date, the Company will record the SciClone Common Stock at fair market value and
will record the unrealized gain or loss, respectively, net of tax, as a
component of stockholders' equity until realized.

Subsequent Accounting for the Company's Right to Receive Additional Shares of
SciClone Common Stock. To the extent that the subsequent market value of the
SciClone Common Stock is above or below the market value on the Closing Date,
the Company will record the right to receive Additional Shares of SciClone
Common Stock at its intrinsic value, which approximates fair market value, and
will record the unrealized loss or gain, respectively, net of tax, as a
component of stockholders' equity until realized. On the date the Company
receives Additional Shares, if any, the Company will record the Additional
Shares received at the then fair market value and will reduce the right to
receive Additional Shares of SciClone Common Stock by a corresponding amount.


                                      -27-
<PAGE>   31


PRO FORMA FINANCIAL INFORMATION

The Company has prepared an unaudited pro forma balance sheet which presents the
financial position of the Company as of December 31, 1997, assuming that the
SciClone Transaction and the application of the net proceeds thereof occurred as
of December 31, 1997. The Company has also prepared an unaudited pro forma
statement of operations for the year ended December 31, 1997, assuming the
SciClone Transaction and the application of the net proceeds thereof occurred as
of January 1, 1997. The unaudited pro forma balance sheet and the unaudited pro
forma statement of operations have been prepared using the market price of the
SciClone Common Stock of $3.25 per share as of March 20, 1998. Because the
Company will record the SciClone Transaction based upon the market price of the
SciClone Common Stock on the Closing Date, the pro forma financial information
may not reflect the actual gain on the SciClone Transaction, nor the proceeds
that the Company would be able to realize from the sale of the SciClone Common
Stock. This unaudited pro forma financial information is located at pages F-1
through F-5 of this Proxy Statement. The unaudited pro forma financial
information should be read in conjunction with the historical financial
statements of the Company, including the notes thereto.

EFFECT OF THE SCICLONE TRANSACTION ON STOCKHOLDERS

        The SciClone Transaction does not involve an exchange of, or a change in
the terms of, the outstanding shares of the Common Stock, nor does the
transaction require the Company to issue additional shares of the Common Stock
or any other securities. Accordingly, the transaction will not change the legal
rights and preferences of any of the Company's stockholders, each of whom will
continue to hold after the transaction the same number and percentage of shares
as such stockholder held prior to the transaction. Stockholders do not have
appraisal rights with respect to the transaction.

SCICLONE PHARMACEUTICALS, INC.

        SciClone is a pharmaceutical company engaged in the acquisition,
development and commercialization of proprietary drugs for treating chronic and
life-threatening diseases for which there are no adequate treatment modalities,
including chronic hepatitis B, chronic hepatitis C, cancer, immune system
disorders and cystic fibrosis.

        SciClone was incorporated in California in 1990. Its address is 901
Mariners Island Boulevard, #315, San Mateo, California 94404, and its telephone
number at that address is (650) 358-3456.

NO REGULATORY APPROVALS

        No governmental or regulatory approvals are required in order for the
Company to effect the SciClone Transaction. SciClone has advised the Company
that no governmental or regulatory approvals are required in order for SciClone
to effect the SciClone Transaction.


                                      -28-
<PAGE>   32


VOTING REQUIREMENTS

        The right of the Company to receive royalty payments from the sale by
SciClone of Licensed Products is the Company's only material source of revenue.
Because of the emphasis that the Company had placed on Thymosin alpha 1 and the
amount of resources expended on the research and development of Thymosin alpha 1
since the Company's inception, the Company has been advised by counsel that the
SciClone Transaction may constitute a sale by the Company of substantially all
of its assets within the meaning of Section 271 of the Delaware General
Corporation Law. Under this statutory provision, approval of such a transaction
requires the affirmative vote of the holders of a majority of the outstanding
shares of the Common Stock.

THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE FOR THE SALE OF THE
COMPANY'S THYMOSIN ALPHA 1 ROYALTY RIGHTS TO SCICLONE.

                    AMENDMENT TO CERTIFICATE OF INCORPORATION

        The Board of Directors has approved and declared advisable an amendment
to Article 4 of the Company's Certificate of Incorporation to increase the
number of authorized shares of Common Stock from 20 million to 75 million.

        As of December 31, 1997, there were 11,977,429 shares of Common Stock
outstanding. In addition (i) 945,000 shares were reserved for issuance upon the
upon the exercise of outstanding Class D Warrants and other warrants and (ii)
1,777,793 shares were reserved for issuance upon the exercise of outstanding
options issued under the Company's stock option plans. This leaves a total of
5,299,778 shares of Common Stock available for other corporate purposes. None of
the one million shares of Preferred Stock authorized by the Certificate of
Incorporation are outstanding.

        The additional 55 million shares of Common Stock would be part of the
existing class of Common Stock and, if and when issued, would have the same
rights and privileges as the shares of Common Stock currently outstanding. If
the proposed amendment to the Certificate of Incorporation is approved, the
Board of Directors will be empowered, without the necessity of further action or
authorization by the stockholders (unless otherwise required by applicable law
or regulations) to cause the Company to issue, from time to time, the 55 million
additional shares of Common Stock on such terms as it may determine. The holders
of the Common Stock have no preemptive rights to purchase or otherwise acquire
any shares of Common Stock or Preferred Stock that may be issued in the future.

        The increase in the number of shares of Common Stock is intended to
ensure that there will be a sufficient number of authorized but unissued shares
available in the future for general corporate purposes, including for issuance
by the Company in connection with financing transactions. Although the Company
has no present plans to issue (other than pursuant to existing contractual
obligations under outstanding options and warrants) any additional shares of
Common Stock or shares of Preferred Stock, it has from time to time in the past,
and expects from time to time in the future, to review various transactions that
could result in the issuance of such shares.

        The issuance of shares of Preferred Stock or shares of Common Stock
under some circumstances could be disadvantageous to current stockholders,
because to do so would dilute their percentage ownership interest in the
Company. In addition, the issuance of the shares of Preferred Stock or Common
Stock could be used by incumbent management to impede, and thereby discourage,
an attempt to acquire control of the Company, even though some or all of the
stockholders of the Company may deem such an acquisition to be


                                      -29-
<PAGE>   33


desirable. For example, the shares could be placed with purchasers who might
support the Board of Directors in opposing a hostile takeover bid. The General
Corporation Law of the State of Delaware permits the issuance of classes of
shares with voting rights under which a majority vote of the holders of each
class, voting separately, is required to approve a merger. Shares of Preferred
Stock could be issued with such rights which could make approval of a merger
more difficult. The issuance of new shares of Common Stock could also be used to
dilute the stock ownership and voting power of a third party seeking to effect a
merger, sale of assets or similar transaction. In the event and to the extent
the proposed amendment facilitates such actions, it could serve to perpetuate
incumbent management.

        The affirmative vote of the holders of a majority of the outstanding
shares of Common Stock is required to approve the proposed amendment to the
Certificate of Incorporation.

        THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE FOR THE
PROPOSED AMENDMENT TO THE CERTIFICATE OF INCORPORATION.

                                 RATIFICATION OF
                       APPOINTMENT OF INDEPENDENT AUDITORS

        The firm of Price Waterhouse LLP has been the independent auditors of
the Company since 1982. The Board of Directors has appointed Price Waterhouse
LLP to serve as the Company's independent auditors for the fiscal year ending
December 31, 1998. While not required to do so, the Board of Directors is
submitting the selection of Price Waterhouse LLP for ratification in order to
ascertain the views of the stockholders. If the selection is not ratified, the
Board of Directors will reconsider the selection. Ratification of the selection
requires the affirmative vote of the holders of a majority of the shares of
Common Stock present in person or represented by proxy and entitled to vote at
the Annual Meeting.

        A representative of Price Waterhouse LLP will be present at the Annual
Meeting, will be afforded an opportunity to make a statement if he or she
desires to do so and will be available to respond to appropriate questions.

THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE FOR THE SELECTION OF
PRICE WATERHOUSE LLP AS THE COMPANY'S INDEPENDENT AUDITORS.

                 MARKET FOR THE COMMON STOCK AND RELATED MATTERS

        The outstanding equity securities of the Company consist of shares of
Common Stock and Class D Warrants. The Common Stock was initially issued to the
public in 1986 and is traded on the OTC Bulletin Board under the symbol ALBM.
There is no public market for the Class D Warrants. On February 28, 1997, the
Company's outstanding Class C Warrants expired.

        The following table sets forth the high and low bid prices as reported
by OTC Bulletin Board for the Common Stock for the periods indicated. OTC
Bulletin Board quotations reflect inter-dealer prices, without retail mark-up,
mark-down, or commission, and may not represent actual transactions.


                                      -30-
<PAGE>   34


<TABLE>
<CAPTION>
                                    High           Low
                                    ----           ---
<S>                                 <C>            <C>
For the year ended
    December 31, 1997:
         First Quarter              $.12           $.08
         Second Quarter             $.13           $.03
         Third Quarter              $.125          $.08
         Fourth Quarter             $.09           $.04

For the year ended
    December 31, 1996:
         First Quarter              $.625          $.125
         Second Quarter             $.4325         $.15625
         Third Quarter              $.25           $.09375
         Fourth Quarter             $.23           $.0625
</TABLE>

        On March 20, 1998, the high and low bid prices for the Common Stock as
reported on the OTC Bulletin Board was $.04. On December 16, 1997, the day
before the Company announced its entry into the Acquisition Agreement, the high
and low bid prices for the Common Stock as reported on the OTC Bulletin Board
were $.06 and $.05, respectively.

        As of March 6, 1998, there were approximately 1,150 holders of record of
the Common Stock.

        The Company has not paid a dividend on the Common Stock and does not
anticipate that any cash dividends will be paid in the foreseeable future.

          ANNUAL REPORT TO STOCKHOLDERS AND INCORPORATION BY REFERENCE

        Accompanying this Proxy Statement is a copy of the Company's 1997 Annual
Report to Stockholders (the "Annual Report"), including the Company's audited
financial statements for the year ended December 31, 1997, which consists
primarily of the Company's Annual Report on Form 10-K for the year ended
December 31, 1997 (the "Form 10-K").

The following information contained in the Annual Report is incorporated by
reference into this Proxy Statement: (i) the section captioned "Business" (pages
2 to 8 of the Form 10-K), (ii) the section captioned "Properties" (page 8 of the
Form 10-K), (iii) the section captioned "Legal Proceedings" (page 8 of the Form
10-K), (iv) the section captioned "Selected Financial Data" (page 11 of the Form
10-K), (v) the section captioned "Management's Discussion and Analysis of
Financial Condition and Results of Operations" (pages 12 to 19 of the Form
10-K), (vi) the section captioned "Changes in and Disagreements with Accountants
on Accounting and Financial Disclosure" (page 19 of the Form 10-K), and (vii)
the section captioned "Financial Statements and Supplementary Data" (pages 19 to
38 of the Form 10-K). No other information contained in the Annual Report is or
is deemed incorporated by reference in this Proxy Statement. Any statement
contained in the Annual Report shall be deemed to be modified or superseded to
the extent that it is modified or superseded by information contained in this
Proxy Statement.


                                      -31-
<PAGE>   35


                DISCRETIONARY VOTING OF PROXIES ON OTHER MATTERS

        The Board of Directors does not now intend to bring before the Annual
Meeting any matters other than those disclosed in the notice of the meeting, and
it does not know of any business that persons other than the management intend
to present at the meeting. Should any other matter requiring a vote of the
stockholders arise, the proxies in the enclosed form confer upon the person or
persons entitled to vote the shares represented by such proxies discretionary
authority to vote such shares in accordance with their best judgment in respect
of any such other matter.

                       SUBMISSION OF STOCKHOLDER PROPOSALS

        Any stockholder proposal intended to be presented at next year's Annual
Meeting must be received by the Company at its executive offices located at 6707
Democracy Boulevard, Suite 111, Bethesda, Maryland 20817 not later than ________
__, 1998, in order to be considered for inclusion in the Company's proxy
statement and form of proxy for such meeting.

ALL SHAREHOLDERS ARE URGED TO COMPLETE, SIGN, DATE AND RETURN THE ACCOMPANYING
PROXY CARD IN THE ENCLOSED ENVELOPE.

                                                       By Order of the Board of
                                                       Directors



                                                       ROBERT J. LANHAM
                                                       Secretary

Bethesda, Maryland
March __, 1998


                                      -32-
<PAGE>   36


UNAUDITED PROFORMA FINANCIAL INFORMATION

The following unaudited pro forma balance sheet presents the financial position
of the Company as of December 31, 1997, assuming that the SciClone Transaction
and the application of the net proceeds thereof, occurred as of December 31,
1997. The unaudited pro forma statement of operations for the year ended
December 31, 1997 has been prepared assuming the SciClone Transaction and the
application of the net proceeds thereof occurred as of January 1, 1997. The
unaudited pro forma balance sheet as of December 31, 1997 and the unaudited pro
forma statement of operations for the year ending December 31, 1997 have been
prepared using the market price of the SciClone Common Stock of $3.25 per share
as of March 20, 1998. Because the Company will record the SciClone Transaction
based upon the market price of the SciClone Common Stock on the Closing Date,
the pro forma financial information may not reflect the actual gain on the
SciClone Transaction, nor the actual proceeds that the Company would be able to
realize from the sale of the SciClone Common Stock. The unaudited pro forma
balance sheet as of December 31, 1997 and the unaudited pro forma statement of
operations for the year ended December 31, 1997 are based on the historical
balance sheet and statement of operations for the Company.

The unaudited pro forma financial information give effect to certain pro forma
adjustments which are described in the notes to these statements. Certain
nonrecurring gains that may result from the above sale and the application of
the proceeds thereof, such as the gain from the reduction in liabilities to
certain vendors, are not included in the unaudited pro forma statements of
operations, but will be reflected in the Company's results of operations when
realized.

The unaudited pro forma financial information is presented for informational
purposes only and is not necessarily indicative of the financial position or
results of operations which would have been achieved had the above sale and the
application of the proceeds thereof been completed as of the respective date or
periods presented, nor is it necessarily indicative of the Company's future
financial position or results of operations. The unaudited pro forma financial
information should be read in conjunction with the historical financial
statements of the Company, including the notes thereto.


                                       F-1
<PAGE>   37


                           ALPHA 1 BIOMEDICALS, INC.
                        UNAUDITED PRO FORMA BALANCE SHEET


<TABLE>
<CAPTION>
                                                                                                             Pro forma
                                                                     December 31,        SciClone           December 31,
                                                                         1997           Transaction             1997
                                                                         ----           -----------             ----
<S>                                                                  <C>               <C>                  <C>
ASSETS
- ------

Current assets
      Cash and cash equivalents                                      $     21,369      $    130,000  (1)    $    151,369
      Investment in SciClone common stock                                     -           1,443,374  (1)       1,443,374
      Right to receive additional shares of SciClone
       common stock                                                           -             356,626  (1)         356,626
      Prepaid insurance                                                    46,988               -                 46,988
                                                                     ------------      ------------         ------------
            Total current assets                                           68,357         1,930,000            1,998,357

Fixed assets, net                                                           1,304               -                  1,304
Due from related party                                                      2,197               -                  2,197
                                                                     ------------      ------------         ------------

            Total assets                                             $     71,858      $  1,930,000         $  2,001,858
                                                                     ============      ============         ============

LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT)
- ----------------------------------------------

Current liabilities
      Accounts payable                                               $    276,215      $        -           $    276,215
      Accrued expenses                                                    408,801          (269,300) (2)         139,501
      Notes payable                                                       110,000               -                110,000
      Letter agreements with vendors                                    1,290,503          (388,503) (2)         902,000
      Deferred revenue                                                     65,000               -                 65,000
                                                                     ------------      ------------         ------------

            Total current liabilities                                   2,150,519          (657,803)           1,492,716
                                                                     ------------      ------------         ------------



Stockholders' equity (deficit)
      Preferred stock, $.001 par value per share,
       1,000,000 authorized; no shares issued                                 -                 -                    -
      Common stock, par value $.001 per share,
      20,000,000 shares authorized; 11,977,429
       issued and outstanding                                              11,977               -                 11,977
      Additional paid-in capital                                       35,965,289               -             35,965,289
      Accumulated deficit                                             (38,055,927)        2,587,803  (3)     (35,468,124)
                                                                     ------------      ------------         ------------

            Total stockholders' equity (deficit)                       (2,078,661)        2,587,803              509,142
                                                                     ------------      ------------         ------------

            Total liabilities and stockholders' equity (deficit)     $     71,858      $  1,930,000         $  2,001,858
                                                                     ============      ============         ============
</TABLE>


                                      F-2-
<PAGE>   38

                           ALPHA 1 BIOMEDICALS, INC.
                   UNAUDITED PRO FORMA STATEMENT OF OPERATIONS


<TABLE>
<CAPTION>
                                                  Year ended             Pro Forma
                                                December 31, 1997       Adjustments            Pro Forma
                                                -----------------       -----------            ---------
<S>                                             <C>                     <C>                    <C>
Revenues                                        $     215,034           $  (139,104) (4)       $    75,930
                                                -------------           -----------            -----------

Expenses
   Research and product
    development                                        85,695                   -                   85,695
   General and administrative                         784,316                   -                  784,316
                                                -------------           -----------            -----------

Total expenses                                        870,011                   -                  870,011
                                                -------------           -----------            -----------

Operating loss                                       (654,977)             (139,104)              (794,081)
Interest expense                                     (141,364)              137,200  (4)            (4,164)
Interest income                                           911                   -                      911
                                                -------------           -----------            -----------

Net loss                                        $    (795,430)          $    (1,904)           $  (797,334)
                                                =============           ===========            ===========

Basic and diluted net loss per common share     $       (0.07)          $      0.00            $     (0.07)
                                                =============           ===========            ===========
</TABLE>


                                      F-3-
<PAGE>   39


                            ALPHA 1 BIOMEDICALS, INC.

                          NOTES TO UNAUDITED PRO FORMA
                              FINANCIAL INFORMATION

A.      Basis of Presentation

        The unaudited pro forma balance sheet presents the financial position of
the Company as of December 31, 1997, assuming that the SciClone Transaction and
the application of net proceeds thereof, occurred as of December 31, 1997. The
unaudited pro forma balance sheet has been prepared using the market price of
SciClone Common Stock of $3.25 per share as of March 20, 1998. Such pro forma
information is based on the historical balance sheet of the Company.

        The unaudited pro forma statement of operations for the year ended
December 31, 1997 has been prepared assuming that the SciClone Transaction and
the application of the net proceeds thereof occurred as of January 1, 1997. The
unaudited pro forma statement of operations has been prepared using the market
price of SciClone Common Stock of $3.25 per share as of March 20, 1998. The
unaudited pro forma statement of operations is based on the historical
statement of operations of the Company. Certain nonrecurring gains that may
result from the above sale and the application of the proceeds thereof, such as
the gain from the reduction in liabilities to certain vendors, are not included
in the unaudited pro forma statement of operations, but will be reflected in
the Company's results of operations when realized.

        The Company believes that the assumptions used in preparing the
unaudited pro forma financial data provide a reasonable basis for presenting all
of the significant effects of the SciClone Transaction and the application of
the net proceeds thereof and that the pro forma adjustments give effect to those
assumptions in the unaudited pro forma financial information. However, because
the Company will record the SciClone Transaction based upon the market price of
the SciClone Common Stock on the Closing Date, the pro forma financial
information may not reflect the actual gain on the SciClone Transaction, nor the
actual proceeds that the Company would be able to realize from the sale of the
SciClone Common Stock.

B.      Pro Forma Adjustments

Pro forma adjustments to the balance sheet as of December 31, 1997, are made to
reflect the following:

(1) The fair market value of the proceeds to be realized pursuant to the
    SciClone Transaction, which include (i) $130,000 of cash, (ii) 444,115
    shares of SciClone Common Stock Common, and (iii) the right to receive
    additional shares of SciClone Common Stock, subject to a maximum of 155,885
    Additional Shares, if the market value of SciClone Common Stock is below
    $4.053 per share during the Lock-Up Periods. As the sales restriction on the
    SciClone Common Stock expires approximately one year from Closing Date, the
    investment in SciClone Common Stock


                                       F-4
<PAGE>   40


    and the right to receive Additional Shares of SciClone Common Stock are
    classified as current assets.

(2) The effect of Amended Letter Agreements between the Company and four
    vendors, subject to the completion of the SciClone Transaction, which will
    accelerate payments due. In consideration for the acceleration of payments
    due, the vendors have agreed to reduce the Company's aggregate obligation,
    including accrued interest, to $902,000, which the Company has agreed to pay
    from the proceeds of the sale of the SciClone Common Stock received under
    the SciClone Transaction. Letter agreements with vendor adjustments are
    classified as current liabilities based upon the scheduled repayment date.
    The reduction in accrued expenses reflects the elimination of accrued
    interest expense payable under the prior agreements.

(3) The total effect of proceeds received from SciClone pursuant to the SciClone
    Transaction and reduced liabilities under the Amended Letter Agreements.

Pro forma adjustments to the statement of operations for the year ended December
31, 1997, are made to reflect the following:

(4) The elimination of $69,104 of royalty payments and $70,000 of non-refundable
    advanced royalty payments received from SciClone and $137,200 of interest
    expense for the letter agreements to vendors during the year ended December
    31, 1997.


                                      F-5
<PAGE>   41


        PROXY                ALPHA 1 BIOMEDICALS, INC.                     PROXY

             6707 Democracy Boulevard, Suite 111, Bethesda, MD 20817
               Proxy Solicited on Behalf of the Board of Directors
                         Annual Meeting of Stockholders
                        To be Held on _____________ 1998

        Please mark, sign and date on the reverse side, and return in the
        enclosed envelope.

                The undersigned hereby appoints Allan L. Goldstein and Albert
        Rosenfeld, and either of them, as Proxies, each with full power of
        substitution, and hereby authorizes them to represent and to vote, as
        designated below, all the shares of Common Stock of Alpha 1 Biomedicals,
        Inc. held of record by the undersigned on ________, 1998, at the Annual
        Meeting of Stockholders to be held on __________, 1998, or at any
        adjournment thereof, as follows:

        1.      Election of Directors
                Allan L. Goldstein, Joseph C. McNay, Albert Rosenfeld, Michael
                L. Berman
                [  ]  FOR all nominees listed above
                [  ]  FOR all nominees listed above except _____________________
                [  ]  WITHHOLD AUTHORITY to vote for all nominees listed above

        2.      Proposal to approve the sale to SciClone Pharmaceuticals, Inc.
        of the Company's rights to receive royalties from the sale of Thymosin
        alpha 1.

                [  ] FOR               [  ] AGAINST             [  ] ABSTAIN

                                 (Continued, and to be signed on the other side)
        ------------------------------------------------------------------------

        3.      Proposal to approve an amendment to the Company's Restated
        Certificate of Incorporation to increase the authorized shares of Common
        Stock from 20 million to 75 million.

                [  ] FOR               [  ] AGAINST             [  ] ABSTAIN

        4.      Proposal to ratify the appointment of Price Waterhouse LLP as
        independent auditors for the fiscal year ended December 31, 1998.

                [  ] FOR               [  ] AGAINST             [  ] ABSTAIN

        5.      In their discretion upon such other business as may properly
        come before the meeting. The Board of Directors recommends a vote "FOR"
        the director nominees and "FOR" proposal numbers 1-4.

        This proxy, when properly executed will be voted in the manner directed
        herein by the undersigned stockholder. If no direction is given, a
        properly executed proxy will be voted "FOR" the director nominees and
        "FOR" proposal numbers 2,3 and 4.

        Signature:                                  Dated
                  ---------------------------------      -----------------------
        Signature if jointly held
                                 -----------------------------------------------

        Please sign exactly as name appears on this card. If shares are held as
a joint tenancy, both tenants should sign. Person signing as executors,
administrators, trustees, or guardians should so indicate when signing. If a
corporation, please sign in full corporate name by president or other authorized
officer. If a partnership, please sign in partnership name by authorized person.




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