ALFACELL CORP
4, 1996-04-10
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>

FORM 4 

                             U.S. SECURITIES AND EXCHANGE COMMISSION
                                    WASHINGTON, D.C. 20549
                        STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

<square>Check this box if no longer
subject to Section 16. Form 4     Filed pursuant to Section 16(a) of the
or Form 5 obligations          Securities Act of 1934, Section 17(a) of the 
may continue.  SEE            Public Utility Holding Company Act of 1935 or 
Instruction 1(b).       Section 30(f) of the Investment Company Act of 1940


<TABLE>
<CAPTION>
1. Name and Address of Reporting Person        2. Issuer Name and Ticker or Trading Symbol   6.  Relationship of Reporting Person
                                                                                             to Issuer
SIEGEL,                           ALLEN                     ALFACELL CORPORATION (ACEL)             (Check all applicable)

                                                                                                   X     Director______ 10% Owner
<S>                                            <C>        <C>   <C> <C>      <C>    <C>      <C>            <C>         <C>
(Last)              (First)           (Middle) 3. IRS or Social     4. Statement for            ________ Officer     ______ Other
                                               Security Number of      Month/Year               (give title below)
C/O ALFACELL CORPORATION, 225 BELLEVILLE       Reporting Person                              (specify below)
AVENUE                                         (Voluntary)                 MARCH 1996
                                                                                          __________________________________________
                   (Street)                                         5. If Amendment,
                                                                       Date of Original
BLOOMFIELD, NEW JERSEY                                              (Month/Year)
07003
(City)              (State)              (Zip)
                                               TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
1. Title of Security                           2. Trans-  3. Trans- 4. Securities Acquired   5. Amount of   6. Owner-   7. Nature
   (Instr. 3)                                     action     action    (A) or Disposed of       Securities     ship        of In-
                                                  Date       Code      (D)                      Beneficially   Form:       direct
                                                  (Month/  (Instr.     (Instr. 3, 4 and 5)      Owned at       (D) or      Bene-
                                                 Day/       8)                                  End of         Indirect    ficial
                                                 Year)                                          Month          (I)         Owner-
                                                                                                (Instr. 3      (Instr.     ship
                                                                                               and 4)         4)           (Instr.
                                                                                                                            4)
                                                          Code   V   Amount  (A) or Price
                                                                               (D)

COMMON STOCK                                    3/25/96     S        2,000     D     $4.75

Common Stock                                    3/25/96     S        2,000     D     $4.81

COMMON STOCK                                    3/26/96     S        6,000     D     $4.75

Common Stock                                    3/27/96     S        1,500     D     $4.63

COMMON STOCK                                    3/27/96     S        2,000     D     $4.75

Common Stock                                    3/27/96     S        2,500     D     $4.56

Common Stock                                    3/28/96     S        6,000     D     $4.56

Common Stock                                    3/29/96     S        5,000     D     $5.00      94,777           D          ---

                                                                                                40,485           I       BY WIFE +
</TABLE>

Reminder: Report on a separate line for each class of securities beneficially
owned directly or indirectly.
                                               (Over)













<PAGE>

FORM 4 (CONTINUED)


TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
               (E.G., puts, calls, warrants, options, convertible securities)

<TABLE>
<CAPTION>
1. Title of Derivative 2.Conver-3.Trans-4.Transac-5.Number of6.Date    7.Title and Amount8.Price 9.Number 10.Owner-11.Na-
Security                 sion     action tion      Deriv-     Exercisableof Under-lying      of   of      ship      ture
   (Instr. 3)            or       Date   Code      ative      and        Securities (Instr. Deriv- Deriv-Form   of In-
                        xercise(Month/Day/(Instr. Securities Expiration 3 and 4)           ative  ative  of De-  direct
                        Price    Year)     8)       Ac-       Date                         Secur- Secur- rivativeBene-
                         of                         quired (A)(Month/Day/                   ity    ities Secur- ficial
                         Deriv-                     or Dis-    Year)                      (Instr.  Bene- ity:    Own-
                         ative                      posed of                                5)    ficially (D) or  ership
                       Security                     (D)                                       Owned  Indi-    (Instr. 4)  
                                                  (Instr. 3,                                     at End     rect (I)
                                                   4, and 5)                                     of        (Instr. 4)
                                                                                                  Month
                                                                                                (Instr. 4)
<S>                    <C>      <C>    <C><C><C>    <C>   <C>   <C>    <C>         <C>    <C>   <C>       <C>     <C>
                                       Code  V    (A) (D)     Date  Expira-    Title   Amount
                                                              Exer- tion               or
                                                              cisableDate              Number
                                                                                        of
                                                                                        Shares
Stock Option++ (right  $4.66   12/31/95 A  V  15,000           +++  12/31/01  Common  15,000    $4.66  15,000    D    ___
to buy)                                                                       Stock
Stock Option (right to $2.68   3/25/96  X            4,000   5/5/93  7/31/96  Common   4,000    $2.68            D    ---
buy)                                                                          Stock
tock Option (right to  $2.68   3/26/96  X            6,000   5/5/93  7/31/96  Common   6,000    $2.68            D    ---
buy)                                                                          Stock 
Stock Option (right to $2.68   3/27/96  X            6,000   5/5/93  7/31/96  Common   6,000    $2.68            D    ---
buy)                                                                          Stock     
Stock Option (right to $2.68   3/28/96  X            6,000   5/5/93  7/31/96  Common   6,000    $2.68            D    ---
buy)                                                                          Stock        
Stock Option (right to $2.68   3/29/96  X            5,000   5/5/93  7/31/96  Common   5,000    $2.68  73,000    D    ---
buy)                                                                          Stock  
</TABLE>

  Explanation of Responses:

  +    The reporting person disclaims beneficial ownership of these securities
       and this report shall not be deemed on admission that the reporting
       person is the beneficial owner of such securities for purposes of
       Section 16 or for any other purpose.
 ++    Granted under the Company's 1993 Stock Option Plan, a Rule 16b-3 Plan.
+++    The option shall become exercisable on December 31, 1996; provided that
       the reporting person serves continuously on the Company's board of
       directors until such time.
++++   Power of attorney is attached hereto.






** Intentional misstatements or omissions of facts constitute Federal Criminal
   Violations .
                          /S/ KEVIN T. COLLINS                        04/10/96
                         Signature of Reporting Person                Date
                         Kevin T. Collins, as attorney-in-face++++
   SEE 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
                                                                     
                         

Note:  File three copies of this Form, one of which must be manually signed.
   If space provided is insufficient, SEE Instruction 6 for procedure.
                                                      SEC 1474 (8-92)
















<PAGE>


                                              POWER OF ATTORNEY

      Know  by  all these presents, that the undersigned hereby constitutes and
appoints Kevin T.  Collins,  signing  singly, the undersigned's true and lawful
attorney-in-fact to:


            (1)   execute  for  and  on  behalf  of  the  undersigned,  in  the
                  undersigned's  capacity as  an  officer  and/or  director  of
                  Alfacell Corporation  (the  "Company"),  Forms  3, 4 and 5 in
                  accordance with Section 16(a) of the Securities and  Exchange
                  Act of 1934 and the rules thereunder;

            (2)   do  and  perform  any  and  all acts for and on behalf of the
                  undersigned which may be necessary  or  desirable to complete
                  and execute any such Form 3, 4 or 5 and timely file such form
                  with the United States Securities and Exchange Commission and
                  any stock exchange or similar authority; and

            (3)   take  any other action of any type whatsoever  in  connection
                  with the foregoing which, in the opinion of such attorney-in-
                  fact, may  be  of  benefit  to,  in  the best interest of, or
                  legally  required by, the undersigned,  it  being  understood
                  that  the documents  executed  by  such  attorney-in-fact  on
                  behalf  of the undersigned pursuant to this Power of Attorney
                  shall be  in  such  form  and  shall  contain  such terms and
                  conditions  as  such  attorney-in-fact  may approve  in  such
                  attorney-in-facts's discretion.


      The  undersigned hereby grants to such attorney-in-fact  full  power  and
authority to  do  and perform any and every act and thing whatsoever requisite,
necessary, or proper to be done in the exercise of any of the rights and powers
herein granted, as  fully  to all intents and purposes as the undersigned might
or  could  do  if  personally present,  with  full  power  of  substitution  or
revocation, hereby ratifying  and confirming all that such attorney-in-fact, or
such attorney-in-fact's substitutes  or substitutes, shall lawfully do or cause
to be done by virtue of this power of attorney and the rights and powers herein
granted.  The undersigned acknowledges that the foregoing attorneys-in-fact, in
serving in such capacity at the request  of  the undersigned, are not assuming,
nor  is  the  Company  assuming, any of the undersigned's  responsibilities  to
comply with Section 16 of the Securities Exchange Act of 1934.

      This Power of Attorney  shall  remain  in full force and effect until the
undersigned is no longer required to file Forms  3, 4 and 5 with respect to the
undersigned's holdings of and transactions in securities issued by the Company,
unless earlier revoked by the undersigned in a signed  writing delivered to the
foregoing attorney-in-fact.


      IN WITNESS WHEREOF, the undersigned has caused this  Power of Attorney to
be executed as of this 26th day of March, 1996.

                                                         /S/ALLEN SIEGEL
                                                          Signature

                                                          ALLEN SIEGEL
                                                          Print Name
























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