ALFACELL CORP
4/A, 1997-03-28
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                                  March 27, 1997

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549

                  Re:      Alfacell Corporation
                           ALLEN SIEGEL

Ladies and Gentlemen:

         On  behalf  of  Allen  Siegel   ("Siegel"),   a  director  of  Alfacell
Corporation, we hereby submit for electronic filing for Siegel an amended Form 4
- - Statement of Changes in Beneficial Ownership, which was originally filed March
7, 1997.

                  Thank you.

                                            Very truly yours,


                                            /s/THOMAS F. MCINERNEY
                                            Thomas F. McInerney


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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                     FORM 4

                  STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
       Section 17(a) of the Public Utility Holding Company Act of 1935 or
               Section 30(f) of the Investment Company Act of 1940

[  ] Check this box if no longer subject of Section 16. Form 4 or Form 5
     obligations may continue. See Instruction 1(b).

================================================================================
1. Name and Address of Reporting Person

Siegel                   Allen
- --------------------------------------------------------------------------------
   (Last)               (First)                 (Middle)

c/o Alfacell Corporation, 225 Belleville Avenue
- --------------------------------------------------------------------------------
                                    (Street)

Bloomfield, New Jersey                            07003
- --------------------------------------------------------------------------------
   (City)               (State)                 (Zip)


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2. Issuer Name and Ticker or Trading Symbol


Alfacell Corporation (ACEL)
================================================================================
3. IRS or Social Security Number of Reporting Person (Voluntary)


================================================================================
4. Statement for Month/Year

February, 1997
================================================================================
5. If Amendment, Date of Original (Month/Year)

March, 1997
================================================================================
6. Relationship of Reporting Person to Issuer
   (Check all applicable)

   [ X ]   Director                             [   ]   10% Owner
   [   ]   Officer (give title below)           [   ]   Other (specify below)



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================================================================================
           Table I -- Non-Derivative Securities Acquired, Disposed of,
                             or Beneficially Owned
================================================================================
<PAGE>


<TABLE>
<CAPTION>
                                                                                                                6.
                                                                 4.                              5.             Owner-
                                                                 Securities Acquired (A) or      Amount of      ship
                                                    3.           Disposed of (D)                 Securities     Form:     7.
                                                    Transaction  (Instr. 3, 4 and 5)             Beneficially   Direct    Nature of
                                      2.            Code         ------------------------------- Owned at End   (D) or    Indirect
1.                                    Transaction   (Instr. 8)                   (A)             of Month       Indirect  Beneficial
Title of Security                     Date          ------------     Amount      or     Price    (Instr. 3      (I)       Ownership
(Instr. 3)                            (mm/dd/yy)     Code     V                  (D)             and 4)         (Instr.4) (Instr. 4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                                   <C>            <C>      <C>    <C>         <C>    <C>      <C>            <C>       <C>

Common Stock                          2/10/97        S               4,000       D      $5.25                   I         By Wife +
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/14/97        S               4,000       D      $5.00                   I         By Wife +
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/18/97        S               2,000       D      $5.00                   I         By Wife +
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/19/97        S               1,000       D      $5.00                   I         By Wife +
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/20/97        S                 100       D      $5.00                   I         By Wife +
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/21/97        S               1,900       D      $5.02     40,785        I         By Wife +
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/27/97        S               2,000       D      $5.81                   D             --
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          2/27/97        S               2,000       D      $5.88     98,777        D             --
- -----------------------------------------------------------------------------------------------------------------------------------

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====================================================================================================================================
</TABLE>
Reminder: Report on a separate line for each class of securities beneficially
owned directly or indirectly


<PAGE>


FORM 4 (continued)

Table II -- Derivative Securities Acquired, Disposed of, or Beneficially Owned
         (e.g., puts, calls, warrants, options, convertible securities)

================================================================================
<TABLE>
<CAPTION>
                                                                                                          9.        10.    
                                                                                                          Number    Owner- 
                                                                                                          of        ship   
                    2.                                                                                    Deriv-    of     
                    Conver-                    5.                              7.                         ative     Deriv-   11.    
                    sion                       Number of                       Title and Amount           Secur-    ative    Nature 
                    of                         Derivative    6.                of Underlying     8.       ities     Secur-   of     
                    Exer-             4.       Securities    Date              Securities        Price    Bene-     ity:     In-    
                    cise     3.       Trans-   Acquired (A)  Exercisable and   (Instr. 3 and 4)  of       ficially  Direct   direct 
                    Price    Trans-   action   or Disposed   Expiration Date   ----------------  Deriv-   Owned     (D) or   Bene-  
1.                  of       action   Code     of(D)         (Month/Day/Year)            Amount  ative    at End    In-      ficial 
Title of            Deriv-   Date     (Instr.  (Instr. 3,    ----------------            or      Secur-   of        direct   Owner- 
Derivative          ative    (Month/  8)       4 and 5)      Date     Expira-            Number  ity      Month     (I)      ship   
Security            Secur-   Day/     ------   ------------  Exer-    tion               of      (Instr.  (Instr.   (Instr.  (Instr.
(Instr. 3)          ity      Year)    Code V    (A)   (D)    cisable  Date     Title     Shares  5)       4)        4)       4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                 <C>      <C>      <C>  <C>  <C>   <C>    <C>      <C>      <C>       <C>     <C>      <C>       <C>      <C>


- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

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====================================================================================================================================
</TABLE>
Explanation of Responses:

+    The reporting person disclaims beneficial ownership of these securities and
this report shall not be deemed an admission that the reporting person is the
beneficial owner of such securities for purposes of Section 16 or for any other
purpose.


/s/ Allen Siegel                                            3/27/97
- ---------------------------------------------            -----------------------
      **Signature of Reporting Person                             Date

**   Intentional misstatements or omissions of facts constitute Federal Criminal
     Violations.

     See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note:  File three copies of this Form, one of which must be manually signed.
       If space provided is insufficient, see Instruction 6 for procedures.




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