CENTOCOR INC
11-K, 1997-06-19
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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<PAGE>
 
                                   FORM 11-K


                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549



(MARK ONE:)

[X]  Annual Report Pursuant to Section 15(d) of the Securities Exchange Act of
     1934


For the fiscal year ended December 31, 1996
                          -----------------

                                      Or

[_]  Transition Report Pursuant to Section 15(d) of the Securities Exchange Act
     of 1934


For the transition period from _________ to __________

                        Commission file number 0-11103
                                               -------

                              CENTOCOR QUALIFIED
                          SAVINGS AND RETIREMENT PLAN

                           (Full title of the Plan)

                                Centocor, Inc.
                           200 Great Valley Parkway
                               Malvern, PA 19355

                    (Name of issuer of the securities held
                  pursuant to the plan and the address of its
                          principal executive office)
<PAGE>
 
Centocor Qualified Savings and Retirement Plan
- ----------------------------------------------
Index to Financial Statements and Schedules
- -------------------------------------------



Page 3      Independent Auditors' Report

Page 4      Statements of Net Assets Available for Plan Benefits as of December
            31, 1996 and 1995

Page 5      Statements of Changes in Net Assets Available for Plan Benefits for
            the years ended December 31, 1996, 1995 and 1994

Pages 6-17  Notes to Financial Statements

Page 18     Item 27a - Schedule of Assets Held For Investment Purposes

Page 19     Item 27d - Schedule of Reportable Transactions

                                       2
<PAGE>
 
                         Independent Auditors' Report
                         ----------------------------

    To the Participants of the Centocor Qualified Savings and Retirement Plan
    and the 401(k) Administrative Committee of Centocor, Inc.:

    We have audited the accompanying statements of net assets available for plan
    benefits of the Centocor Qualified Savings and Retirement Plan as of
    December 31, 1996 and 1995, and the related statements of changes in net
    assets available for plan benefits for each of the years in the three-year
    period ended December 31, 1996.  These financial statements are the
    responsibility of the Plan's management.  Our responsibility is to express
    an opinion on these financial statements based on our audits.

    We conducted our audits in accordance with generally accepted auditing
    standards.  Those standards require that we plan and perform the audit to
    obtain reasonable assurance about whether the financial statements are free
    of material misstatement.  An audit includes examining, on a test basis,
    evidence supporting the amounts and disclosures in the financial statements.
    An audit also includes assessing the accounting principles used and
    significant estimates made by management, as well as evaluating the overall
    financial statement presentation.  We believe that our audits provide a
    reasonable basis for our opinion.

    In our opinion, the financial statements referred to above present fairly,
    in all material respects, the net assets available for plan benefits of the
    Centocor Qualified Savings and Retirement Plan at December 31, 1996 and 1995
    and the changes in net assets available for plan benefits for each of the
    years in the three-year period ended December 31, 1996, in conformity with
    generally accepted accounting principles.

    Our audits were made for the purpose of forming an opinion on the basic
    financial statements taken as a whole.  The supplemental schedule of assets
    held for investment purposes and schedule of reportable transactions are
    presented for the purpose of additional analysis and are not a required part
    of the basic financial statements but are supplemental information required
    by the Department of Labor's Rules and Regulations for Reporting and
    Disclosure under the Employee Retirement Income Security Act of 1974.  The
    supplemental schedules have been subjected to the auditing procedures
    applied in the audits of the basic financial statements and, in our opinion,
    are fairly stated in all material respects in relation to the basic
    financial statements taken as a whole.

    KPMG Peat Marwick LLP
    Philadelphia, PA

    June 4, 1997

                                       3
<PAGE>

                 CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN
              STATEMENTS OF NET ASSETS AVAILABLE FOR PLAN BENEFITS
<TABLE> 
<CAPTION> 


                                                                        December 31,
                                                           --------------------------------------
                                                                1996                  1995
                                                                ----                  ----
<S>                                                             <C>                  <C> 
Assets:

      Corestates Money Market Funds and Cash                      $19,084              $66,553

      Investments (Notes 3 and 9):
            Centocor, Inc. Common Stock                         4,385,274            4,684,664
            CoreFund Treasury Reserve Series A                    958,949              974,245
            CoreFund Intermediate Bond Fund Series A            1,146,541            1,126,224
            CoreFund Equity Index Fund Series A                 6,815,384            4,975,540
            CoreFund International Growth Fund Series A           650,973              381,655
            CoreFund Growth Equity Fund Series A                2,395,407            1,285,902
            Twentieth Century Vista Fund                          486,977                    -
                                                           ---------------       --------------
                                                               16,839,505           13,428,230

      Interest and dividends receivable                            54,795               45,609

      Other assets:
            Employer's contribution receivable (Note 2)           319,818              511,273
            Loans receivable from participants                    173,307              119,756
                                                           ---------------       --------------
                                                                  493,125              631,029
                                                           ---------------       --------------

             Total assets                                     $17,406,509          $14,171,421
                                                           ===============       ==============



Net assets available for Plan Benefits (Notes 2 and 9)        $17,406,509          $14,171,421
                                                           ===============       ==============
</TABLE> 

See accompanying Notes to Financial Statements.

                                       4
<PAGE>
                 CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN
         STATEMENTS OF CHANGES IN NET ASSETS AVAILABLE FOR PLAN BENEFITS

<TABLE> 
<CAPTION> 
                                                                       Years ended December 31,
                                                             ---------------------------------------------
                                                                 1996             1995            1994
                                                                 ----             ----            ----
<S>                                                          <C>              <C>             <C> 
Additions:
      Interest and other income                                  $634,607         $424,163       $196,962
      Net realized gains on sale of investments (Note 3)        1,182,855           57,260        173,613
      Net unrealized appreciation of
        investments (Notes 3 and 9)                               922,405        3,485,055        326,454


      Contributions (Note 2):
            Employee                                            1,560,255        1,465,024      1,340,188
            Employer                                              523,631          511,274        549,798

      Other income (expense)                                       36,646          (22,338)       (40,746)
                                                             -------------    -------------   ------------

                Total additions                                 4,860,399        5,920,438      2,546,269


Deductions (Note 2):
            Benefits paid                                      (1,554,006)        (637,320)    (1,325,833)
            Loan repayments (advances)                            (70,012)          43,352        (80,319)
            Administrative expenses                                (1,293)          (1,305)        (1,963)
                                                             -------------    -------------   ------------
                                                               (1,625,311)        (595,273)    (1,408,115)

                Net increase                                    3,235,088        5,325,165      1,138,154

Net assets available for Plan Benefits:
            Beginning of year                                  14,171,421        8,846,256      7,708,102
                                                             -------------    -------------   ------------
            End of year                                       $17,406,509      $14,171,421     $8,846,256
                                                             =============    =============   ============
</TABLE> 

See accompanying Notes to Financial Statements.

                                       5
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS

Note 1  Summary of Significant Accounting Policies

        Basis of Accounting
        -------------------

        The accompanying financial statements have been prepared on the accrual
        basis of accounting.

        Investments
        -----------

        Shares of common trust funds administered by CoreStates Bank, N.A. (the
        "Trustee") are stated at fair value based on the market value of the
        underlying securities. Centocor, Inc. (the "Company") common shares are
        carried at market value which is determined by quoted market prices.

        Accounting Estimates
        --------------------

        The preparation of financial statements in conformity with generally
        accepted accounting principles requires management to make estimates and
        assumptions that affect the reported amounts of assets and liabilities
        and disclosure of contingent assets and liabilities at the date of the
        financial statements and the reported amounts of additions and
        deductions during the reporting period. Actual results could differ from
        estimates recorded.

        Basis of Security Transactions
        ------------------------------

        Security transactions are accounted for on the trade date.

Note 2  Description of Plan

        The following description of the Centocor Qualified Savings and
        Retirement Plan (the "Plan") provides only general information.
        Participants should refer to the Plan document for a more complete
        description of the Plan's provisions.

        General
        -------

        Effective January 1, 1985, the Company established the Plan, a defined
        contribution savings plan subject to the provisions of the Employee
        Retirement Income Security Act of 1974 ("ERISA"). Substantially all U.S.
        employees of the Company, or any of its

                                       6
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS

        subsidiaries or affiliates, are eligible to participate in the Plan.
        Employees may participate as of the first entry date following the date
        of his/her employment. The entry dates are January 1, April 1, July 1
        and October 1 ("Entry Date") of each calendar year. Substantially all of
        the legal, accounting and administrative expenses associated with Plan
        operations are currently paid by the Company.

        Contributions
        -------------

        Eligible employees may make voluntary tax-deferred contributions of 1 to
        15 percent of their eligible cash compensation up to certain annual
        limits as prescribed by the U.S. Internal Revenue Code. Maximum annual
        contributions may be limited at the discretion of the Company.

        Employee contributions are invested as directed by the employee in any
        of the seven investment programs available under an investment contract
        with the Trustee (see Note 3). Company contributions are made
        principally in the Company's Common Stock.

        The Company may elect, but is not required, to make contributions to the
        Plan for the benefit of the participating employees. To date,
        contributions have been made as a percentage of the participants'
        contributions for the year, as determined by the Company's Board of
        Directors. In 1996, 1995 and 1994, the Company elected to contribute an
        amount equal to 40 percent of the contributions of each employee earning
        less than $70,000 per year and 30 percent of the contributions of each
        employee earning $70,000 or more per year. The Company's contribution is
        based upon annual employee contributions up to a level of 6 percent of
        their cash compensation. Additionally, in 1996, 1995 and 1994, the
        Company committed to make a contribution equal to 1% of each employee's
        compensation. At December 31, 1996, 9,415 shares of the Company's Common
        Stock with a fair value of $33.9688 per share determined by the average
        trade price for the last twenty days in December and $2.42 in cash was
        due to the Plan from the Company for its 1996 contribution.

        Participants' Accounts
        ----------------------

        Separate accounts are maintained by the Trustee for each participant.
        Each participant's account reflects the participant's contribution, the
        Company's contribution, interest, dividends, other income, and gains or
        losses earned by each of the investment programs. Investment income is
        reinvested in the same programs.

                                       7
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS


        Participants may transfer all or a portion of their accounts among the
        seven investment programs available under the Plan. The transfer would
        take effect on the Entry Date following the participant's written notice
        of the change.

        Vesting
        -------

        Employee contributions are fully (100 percent) vested and non-
        forfeitable. Employer contributions are fully vested upon death, total
        and permanent disability, or attainment of age 65; otherwise, employer
        contributions are subject to vesting percentages based on years of
        service, as defined by the Plan documents. Employee non-vested
        forfeitures are used by the Company to offset employer contributions.
        The employer contributions vesting percentages are as follows:

               Less than one year of service   0%
               One year of service            20%
               Two years of service           40%
               Three years of service         60%
               Four years of service          80%
               Five or more years of service 100%

        Payment of Benefits
        -------------------

        Benefits from the participants' vested accounts are normally payable to
        Plan participants upon retirement, death, termination of Company
        employment or total and permanent disability. Included in plan equity
        are benefits payable at December 31, 1996 and 1995 of $150,240 and
        $354,293, respectively, representing amounts due to former employees.

        A participant, while still an employee, may generally withdraw all or a
        portion of his vested, non-forfeitable tax-deferred contribution account
        if such amount is needed to defray the cost of a medical emergency,
        enable the participant to acquire or improve his principal residence, or
        assist the participant in preventing eviction or foreclosure
        proceedings. Such a withdrawal must first be taken as a loan as noted
        below. Any additional funds required will be distributed as a hardship
        withdrawal subject to income tax and penalties. Such loan and withdrawal
        shall not exceed the amount required to meet the immediate financial
        need created by the hardship and shall not be reasonably available from
        other sources of the participant.

                                       8
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS

        Loan Provisions
        ---------------

        Participants may borrow up to 50 percent of their vested account balance
        not to exceed $50,000 and may take only one loan per year. All such
        loans bear interest at prevailing market rates.
 
Note 3  Investments
        -----------

        The number of employees participating in the investment programs at
        December 31, 1996 was as follows:
<TABLE>
 
        <S>                                            <C>
        Centocor, Inc. Common Stock                    409
        CoreFund Treasury Reserve Series A             152
        CoreFund Intermediate Bond Fund Series A       172
        CoreFund Equity Index Fund Series A            369
        CoreFund International Growth Fund Series A    148
        CoreFund Growth Equity Fund Series A           289
        Twentieth Century Vista Fund                   131
</TABLE>

        The Centocor Common Stock program consists primarily of shares of
        Centocor, Inc. Common Stock, with a portion of funds invested in a
        government money market fund pending purchase of the Company's Common
        Stock to provide liquidity. The CoreFund Treasury Reserve Series A
        invests in U.S. Treasury Bills with maturities of one-year or less, with
        a portion invested in the money market fund noted above. The CoreFund
        Intermediate Bond Fund Series A invests in U.S. government and
        government agencies securities and securities guaranteed by the U.S.
        government as well as unsecured debt instruments of corporations, all
        with various maturities up to ten years. Part of this fund may also be
        invested in the money market fund noted above. The CoreFund Equity Index
        Fund Series A invests in equity securities of corporations, with a
        portion in the money market fund noted above. The CoreFund International
        Growth Fund Series A invests in equity securities of corporations
        outside the United States. The CoreFund Growth Equity Fund Series A
        invests in equity securities of corporations, with a portion in the
        money market fund noted above. The Twentieth Century Vista Fund invests
        primarily in equities of smaller companies.

        Custody of the Plan's investments is maintained by the Trustee. Plan
        investments at December 31, 1996 and 1995 were as follows (see also 
        Note 9):

                                       9
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS
<TABLE>
<CAPTION>
 
 
        Name of Issuer
        and Title of Issue                                      Number of Shares     Cost     Fair Value
        ------------------                                      ----------------  ----------  -----------
 
        At December 31, 1996
        --------------------
        <S>                                                     <C>               <C>         <C> 
          Centocor, Inc. Common Stock                                    122,665  $2,014,233  $ 4,385,274
          CoreFund Treasury Reserve Series A                             958,949     958,949      958,949
          CoreFund Intermediate Bond Fund Series A                       116,282   1,153,285    1,146,541
          CoreFund Equity Index Fund Series A                            217,813   4,972,137    6,815,384
          CoreFund International Growth Fund Series A                     49,731     646,438      650,973
          CoreFund Growth Equity Fund Series A                           178,230   2,106,668    2,395,407
          Twentieth Century Vista Fund                                    33,561     520,755      486,977
                                                                                              -----------
                                                                                              $16,839,505
                                                                                              ===========
<CAPTION> 

        Name of Issuer
        and Title of Issue                                      Number of Shares     Cost     Fair Value
        ------------------                                      ----------------  ----------  -----------
 
        At December 31, 1995
        --------------------
        <S>                                                     <C>               <C>         <C>  
          Centocor, Inc. Common Stock                                    151,730  $2,282,264  $ 4,684,664
          CoreFund Treasury Reserve Series A                             974,245     974,245      974,245
          CoreFund Intermediate Bond Fund Series A                       112,961   1,122,518    1,126,224
          CoreFund Equity Index Fund Series A                            190,488   4,065,866    4,975,540
          CoreFund International Growth Fund Series A                     29,335     352,085      381,655
          CoreFund Growth Equity Fund Series A                           103,953   1,086,619    1,285,902
                                                                                              -----------
                                                                                              $13,428,230
                                                                                              ===========
</TABLE>
 

        Net realized gains of $1,182,855 in 1996 resulted principally from sales
        in the CoreFund Equity Index Fund, the CoreFund Growth Equity Fund and
        shares of the Company's Common Stock.

        Net realized gains of $57,260 in 1995 resulted principally from sales in
        the CoreFund Equity Index Fund and shares of the Company's Common Stock.

        Net realized gains of $173,613 in 1994 resulted principally from sales
        in the CoreFund Equity Index Fund offset by realized losses from sales
        in the CoreFund Intermediate Bond Fund.

                                       10
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS

            The net unrealized appreciation (depreciation) on investments as of
            and for the years ended December 31, 1996, 1995 and 1994 was as
            follows (see Note 9):
<TABLE>
<CAPTION>
 
                                                  CoreFund      CoreFund       CoreFund        CoreFund    Twentieth
                                                Intermediate     Equity      International   Growth Equity  Century
                                Centocor, Inc.   Bond Fund     Index Fund         Fund          Fund         Vista
                                 Common Stock     Series A      Series A       Series A       Series A       Fund          Total
                                ---------------  ----------  -------------- --------------   ----------    ----------  -------------

<S>                             <C>              <C>         <C>            <C>              <C>           <C>          <C>
Balance at December 31, 1993        $ (435,372)   $  3,655      $  164,843       $      -     $      -      $      -     $ (266,874)

Appreciation (depreciation)            666,999     (59,799)       (266,069)        (1,547)     (13,130)            -        326,454
                                    ----------    --------      ----------       --------     --------     ---------     ----------
Balance at December 31, 1994           231,627     (56,144)       (101,226)        (1,547)     (13,130)            -         59,580
Appreciation                         2,170,773      59,851       1,010,900         31,117      212,414             -      3,485,055
                                    ----------    --------      ----------       --------     --------     ---------     ----------
Balance at December 31, 1995        $2,402,400    $  3,707      $  909,674       $ 29,570     $199,284      $      -      3,544,635
Appreciation (depreciation)            (31,359)    (10,451)        933,573        (25,035)      89,455       (33,778)       922,405
                                    ----------    --------      ----------       --------     --------     ---------     ----------
Balance at December 31, 1996        $2,371,041    $ (6,744)     $1,843,247       $  4,535     $288,739      $(33,778)    $4,467,040
                                    ==========    ========      ==========       ========     ========     =========     ==========
</TABLE>

    Note 4  Federal Income Taxes

            The Internal Revenue Service has made a determination that the Plan
            has complied with the requirements of ERISA and therefore is
            qualified under the provisions of Section 401(a) of the Internal
            Revenue Code and is exempt from Federal income tax.

            A participant must pay Federal regular income tax plus a 10 percent
            Federal excise tax for withdrawal of any portion of his accumulated
            pre-tax account balance, including the vested portion of the
            Company's contributions or earnings prior to retirement, disability,
            or attaining age 59-1/2 and not meeting the requirements of a loan.

    Note 5  Plan Termination

            Although it has not expressed an intent to do so, the Company has
            the right under the Plan to discontinue its contributions at any
            time and to terminate the Plan subject to the provisions of ERISA.

    Note 6  Form 5500

            The Plan had not yet prepared its Form 5500 for the year ended 1996
            as of the date of the audit report. The Plan has filed an extension
            until September 15, 1997 to file its 1996 Form 5500.

                                       11
<PAGE>
 
                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS

    Note 7  Plan Amendments/Changes

            During 1996, the plan added one new investment option. This
            investment option is known as the Twentieth Century Vista Fund. The
            object of the Twentieth Century Vista Fund is to seek capital growth
            over time by investing in common stocks considered to have better-
            than-average prospects for appreciation. This fund was added to
            further diversify the investment vehicles offered by the Plan.

            During 1994, the plan added two new investment options. These
            investments are known as the CoreFund Growth Equity Fund Series A
            and the CoreFund International Growth Fund Series A. The objective
            of the CoreFund Growth Equity Fund Series A is to seek capital
            growth by investing primarily in equity securities with potential
            for growth of earnings over time while the CoreFund International
            Growth Fund Series A seeks long-term capital appreciation by
            investing primarily in equity securities of companies located
            outside the United States. These two funds were added to further
            diversity the investment vehicles offered by the Plan.
 
    Note 8  Subsequent Events

            Market Value of Investments
            ---------------------------

            The market value per share of the Company's Common Stock at June 4,
            1997 was $34.50 as compared to $35.75 at December 31, 1996.

            Plan Amendments/Changes
            -----------------------

            Effective July 1, 1997, the Company will change its investment
            administrator and trustee from Corestates, Bank, N.A. to The
            Vanguard Group. As a result, new investments will be offered
            effective July 1, 1997 and the record keeping for the plan will be
            performed by The Vanguard Group. Contributions and vesting schedules
            will remain the same, however, the plan will change from quarterly
            valuation to daily valuation. These changes will provide additional
            services and flexibility to the participants of the Plan.

                                       12
<PAGE>

                CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                         NOTES TO FINANCIAL STATEMENTS


Note 9 Allocation of Plan Assets to Investment Programs
- -------------------------------------------------------

<TABLE> 
<CAPTION> 

                                                                                   December 31, 1996
                                                   ---------------------------------------------------------------------------------
                                                                                                COREFUND             COREFUND
                                                   COREFUND                           INTERMEDIATE        EQUITY      INTER-       
                                                   TREASURY      CENTOCOR                 BOND             INDEX     NATIONAL      
                                                   RESERVE        COMMON      LOAN        FUND             FUND       GROWTH       
                ASSETS                             SERIES A        STOCK      FUND      SERIES A         SERIES A    SERIES A      
                ------                             ---------------------------------------------------------------------------------
<S>                                                 <C>         <C>         <C>         <C>             <C>          <C> 
CORESTATES MONEY MARKET FUNDS AND CASH               $3,933        $6,827     $5,127            -              $3           -       

CENTOCOR INC. COMMON STOCK                                -     4,367,399          -            -               -           -       
COREFUND TREASURY RESERVE SERIES A                  948,979         9,970          -            -               -           -       
COREFUND INTERMEDIATE BOND FUND SERIES A                  -             -          -    1,146,541               -           -       
COREFUND EQUITY INDEX FUND SERIES A                       -             -          -            -       6,815,384           -       
COREFUND INTERNATIONAL GROWTH FUND SERIES A               -             -          -            -               -     650,973       
COREFUND GROWTH EQUITY FUND SERIES A                      -             -          -            -               -           -
TWENTIETH CENTURY VISTA FUND                              -             -          -            -               -           -       

INTEREST AND DIVIDENDS RECEIVABLE                         -             -          -        5,742          28,490      18,389       
EMPLOYER'S CONTRIBUTION RECEIVABLE                        -       319,818          -            -               -           -       
LOANS RECEIVABLE FROM PARTICIPANTS                        -             -    173,307            -               -           -       
                                                   ---------------------------------------------------------------------------------

     TOTAL ASSETS                                   952,912    $4,704,014   $178,434   $1,152,283      $6,843,877    $669,362       
                                                   =================================================================================

<CAPTION> 

                                                   -----------------------------------------------------------------
                                                      COREFUND          COREFUND           TWENTIETH                    
                                                       GROWTH         CONTRIBUTION          CENTURY                     
                                                       EQUITY         /DISTRIBUTION          VISTA                      
                                                      SERIES A           ACCOUNT              FUND          TOTAL       
                                                  ------------------------------------------------------------------   
<S>                                                 <C>                     <C>             <C>           <C>   
CORESTATES MONEY MARKET FUNDS AND CASH                     $12               $3,181               $1         $19,084     
                                                                                                              
CENTOCOR INC. COMMON STOCK                                   -               17,875                -       4,385,274     
COREFUND TREASURY RESERVE SERIES A                           -                    -                -         958,949     
COREFUND INTERMEDIATE BOND FUND SERIES A                     -                    -                -       1,146,541     
COREFUND EQUITY INDEX FUND SERIES A                          -                    -                -       6,815,384     
COREFUND INTERNATIONAL GROWTH FUND SERIES A                  -                    -                -         650,973     
COREFUND GROWTH EQUITY FUND SERIES A                 2,395,407                    -                -       2,395,407     
TWENTIETH CENTURY VISTA FUND                                 -                    -          486,977         486,977     
                                                                                                              
INTEREST AND DIVIDENDS RECEIVABLE                        2,174                    -                -          54,795     
EMPLOYER'S CONTRIBUTION  RECEIVABLE                          -                    -                -         319,818     
LOANS RECEIVABLE FROM PARTICIPANTS                           -                    -                -         173,307     
                                                  ------------------------------------------------------------------
                                                                                                              
          TOTAL ASSETS                              $2,397,593              $21,056         $486,978     $17,406,509     
                                                  ==================================================================

</TABLE> 

                                      13
<PAGE>

                 CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                          NOTES TO FINANCIAL STATEMENTS


Note 9  Allocation of Plan Assets and Liabilities to Investment Programs
        ----------------------------------------------------------------
<TABLE> 
<CAPTION> 

                                                                                    December 31, 1995
                                                   --------------------------------------------------------------------------------
                                                                                                 COREFUND            COREFUND
                                                   COREFUND                            INTERMEDIATE      EQUITY        INTER-      
                                                   TREASURY    CENTOCOR                    BOND          INDEX        NATIONAL     
                                                    RESERVE     COMMON         LOAN        FUND           FUND         GROWTH      
               ASSETS                              SERIES A     STOCK          FUND      SERIES A       SERIES A      SERIES A     
               ------                              --------------------------------------------------------------------------------
     <S>                                           <C>         <C>         <C>           <C>            <C>           <C>    
     CORESTATES MONEY MARKET FUNDS
      AND CASH                                        $7,455     $11,187    $11,712          $3,839       $16,093       $2,792     

     CENTOCOR INC. COMMON STOCK                            -   4,669,226          -               -             -            -     
     COREFUND TREASURY RESERVE SERIES A              974,245           -          -               -             -                  
     COREFUND INTERMEDIATE BOND
      FUND SERIES A                                        -           -          -       1,126,224             -            -     
     COREFUND EQUITY INDEX FUND SERIES A                   -           -          -               -     4,975,540            -     
     COREFUND INTERNATIONAL GROWTH FUND SERIES A           -           -          -               -             -      381,655     
     COREFUND GROWTH EQUITY FUND SERIES A                  -           -          -                             -            -     

     INTEREST AND DIVIDENDS RECEIVABLE                     -           -          -          10,759        24,839        8,337     
     EMPLOYER'S CONTRIBUTION RECEIVABLE                1,484     469,797          -           5,383        13,140        4,173     
     LOANS RECEIVABLE FROM PARTICIPANTS                    -           -    119,756               -             -            -     
                                                   --------------------------------------------------------------------------------
                                                                                                                           
          TOTAL ASSETS                              $983,184  $5,150,210   $131,468      $1,146,205    $5,029,612     $396,957     
                                                   ================================================================================
<CAPTION> 
          LIABILITIES AND PLAN EQUITY
          ---------------------------
     <S>                                           <C>        <C>         <C>          <C>             <C>           <C>    
     NET INTERFUND INVESTMENT REDIRECTION             $9,273   ($514,238)         -       ($111,030)      $93,967      $83,281     
                                                   --------------------------------------------------------------------------------

     PLAN EQUITY                                     973,911   5,664,448    131,468       1,257,235     4,935,645      313,676     
                                                   --------------------------------------------------------------------------------

          TOTAL LIABILITIES AND PLAN EQUITY         $983,184  $5,150,210   $131,468      $1,146,205    $5,029,612     $396,957     
                                                   ================================================================================
<CAPTION> 

                                                                          December 31, 1995
                                                       -----------------------------------------------------     
                                                               COREFUND      COREFUND                            
                                                                GROWTH     CONTRIBUTION                          
                                                                EQUITY     /DISTRIBUTION                         
                                                               SERIES A       ACCOUNT            TOTAL           
                                                       -----------------------------------------------------      
     <S>                                                     <C>           <C>                <C>                  
     CORESTATES MONEY MARKET FUNDS                                                                               
      AND CASH                                                  $10,577            $2,898         $66,553        
                                                                                                                 
     CENTOCOR INC. COMMON STOCK                                       -            15,438       4,684,664        
     COREFUND TREASURY RESERVE SERIES A                                                           974,245        
     COREFUND INTERMEDIATE BOND                                                                                  
      FUND SERIES A                                                   -                 -       1,126,224        
     COREFUND EQUITY INDEX FUND SERIES A                              -                 -       4,975,540        
     COREFUND INTERNATIONAL GROWTH FUND SERIES A                      -                 -         381,655        
     COREFUND GROWTH EQUITY FUND SERIES A                     1,285,902                 -       1,285,902        
                                                                                                                 
     INTEREST AND DIVIDENDS RECEIVABLE                            1,674                 -          45,609        
     EMPLOYER'S CONTRIBUTION  RECEIVABLE                         17,296                 -         511,273        
     LOANS RECEIVABLE FROM PARTICIPANTS                               -                 -         119,756        
                                                       -----------------------------------------------------      
                                                                                                                 
          TOTAL ASSETS                                       $1,315,449           $18,336     $14,171,421        
                                                       ===================================================       
<CAPTION>                                                                                                        
          LIABILITIES AND PLAN EQUITY                                                                
          ---------------------------
     <S>                                                     <C>           <C>                <C>                  
     NET INTERFUND INVESTMENT REDIRECTION                      $438,747                 -               -        
                                                       ---------------------------------------------------       
                                                                                                                 
     PLAN EQUITY                                                876,702            18,336      14,171,421        
                                                       ---------------------------------------------------       
                                                                                                                 
          TOTAL LIABILITIES AND PLAN EQUITY                  $1,315,449           $18,336     $14,171,421        
                                                       ===================================================       
</TABLE> 

                                      14
<PAGE>

                  CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                          NOTES TO FINANCIAL STATEMENTS

<TABLE> 
<CAPTION> 

Note 10  Allocation of Plan Income and Changes in Plan Equity to Investment Programs
         ---------------------------------------------------------------------------

                                                                          Year ended December 31, 1996
                                             --------------------------------------------------------------------------------------
                                                                                                  COREFUND          COREFUND
                                               COREFUND                               INTERMEDIATE       EQUITY       INTER-       
                                               TREASURY       CENTOCOR                    BOND            INDEX      NATIONAL      
                                               RESERVE         COMMON         LOAN        FUND            FUND        GROWTH       
                                               SERIES A        STOCK          FUND      SERIES A        SERIES A     SERIES A      
                                             --------------------------------------------------------------------------------------
     <S>                                       <C>            <C>            <C>      <C>               <C>          <C> 
     INTEREST & OTHER INCOME                     $46,540         $2,534      $8,135         $60,408     $159,992       $58,615     

     REALIZED GAINS (LOSSES) ON SALE OF
      INVESTMENTS                                      -        960,822           -          (1,155)     157,366        18,727     

     UNREALIZED APPRECIATION
      (DEPRECIATION) OF
      INVESTMENTS                                      -        (31,359)          -         (10,451)     933,573       (25,035)    

     CONTRIBUTIONS:
      EMPLOYEE                                    85,287        247,196           -          92,157      533,457       112,261     
      EMPLOYER                                         -        523,631           -               -            -             -     

     OTHER INCOME (EXPENSE)                            -        (32,487)          -               -            -             -     

     DEDUCTIONS:
      BENEFITS PAID                              (99,571)      (358,319)          -        (110,901)    (646,210)     (115,260)    
      LOAN REPAYMENTS/(ADVANCES)                       -              -     (70,012)              -            -             -     
      ADMINISTRATIVE EXPENSES                          -              -      (1,293)              -            -             -     
      NET INTERFUND INVESTMENT REDIRECTION       (53,255)    (2,272,452)    110,136        (135,010)     770,054       306,378     
                                             --------------------------------------------------------------------------------------

     NET INCREASE (DECREASE)                     (20,999)      (960,434)     46,966        (104,952)   1,908,232       355,686     

     PLAN EQUITY AT
      BEGINNING OF PERIOD                        973,911      5,664,448     131,468       1,257,235    4,935,645       313,676     
                                             --------------------------------------------------------------------------------------
     PLAN EQUITY AT
      END OF PERIOD                             $952,912     $4,704,014    $178,434      $1,152,283   $6,843,877      $669,362     
                                             ======================================================================================
<CAPTION> 

                                                              Year ended December 31, 1996
                                              ------------------------------------------------------------------  
                                                                                                                  
                                                    COREFUND                        TWENTIETH                     
                                                     GROWTH          COREFUND        CENTURY                      
                                                     EQUITY        CONTRIBUTION       VISTA                       
                                                    SERIES A       /DISTRIBUTION       FUND            TOTAL      
                                              ------------------------------------------------------------------  
     <S>                                            <C>            <C>              <C>               <C> 
     INTEREST & OTHER INCOME                         $261,348                $641      $36,394        $634,607    
                                                                                                                  
     REALIZED GAINS (LOSSES) ON SALE OF                                                                           
      INVESTMENTS                                      47,157                   -          (62)      1,182,855    
                                                                                                                  
     UNREALIZED APPRECIATION                                                                                      
      (DEPRECIATION) OF                                                                                           
      INVESTMENTS                                      89,455                   -      (33,778)        922,405    
                                                                                                                  
     CONTRIBUTIONS:                                                                                               
      EMPLOYEE                                        346,090                   -      143,807       1,560,255    
      EMPLOYER                                              -                   -            -         523,631    
                                                                                                                  
     OTHER INCOME (EXPENSE)                                 -              69,133            -          36,646    
                                                                                                                  
     DEDUCTIONS:                                                                                                  
      BENEFITS PAID                                  (212,073)                  -      (11,672)     (1,554,006)   
      LOAN REPAYMENTS/(ADVANCES)                            -                   -            -         (70,012)   
      ADMINISTRATIVE EXPENSES                               -                   -            -          (1,293)   
      NET  INTERFUND INVESTMENT REDIRECTION           988,914             (67,054)     352,289               -    
                                              -----------------------------------------------------------------   
                                                                                                                  
     NET INCREASE (DECREASE)                        1,520,891               2,720      486,978       3,235,088    
                                                                                                                  
     PLAN EQUITY AT                                                                                               
      BEGINNING OF PERIOD                             876,702              18,336            -      14,171,421    
                                              -----------------------------------------------------------------   
     PLAN EQUITY AT                                                                                               
      END OF PERIOD                                $2,397,593             $21,056     $486,978     $17,406,509    
                                              =================================================================   
</TABLE> 
                                              
                                      15
<PAGE>
                 CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                          NOTES TO FINANCIAL STATEMENTS


Note 10 Allocation of Plan Income and Changes in Plan Equity to Investment 
        ------------------------------------------------------------------
        Programs
        ---------
<TABLE> 
<CAPTION> 
                                                                          Year ended December 31, 1995
                                                    -----------------------------------------------------------------------------
                                                                                                  COREFUND             COREFUND
                                                      COREFUND                            INTERMEDIATE     EQUITY       INTER- 
                                                      TREASURY      CENTOCOR                  BOND          INDEX      NATIONAL
                                                      RESERVE        COMMON      LOAN         FUND          FUND        GROWTH 
                                                      SERIES A        STOCK      FUND       SERIES A      SERIES A     SERIES A
                                                    -----------------------------------------------------------------------------
        <S>                                           <C>           <C>        <C>        <C>             <C>          <C> 
        INTEREST & OTHER INCOME                         $49,704         $450   $14,275        $70,944     $236,371      $10,192 
                                               
        REALIZED GAINS (LOSSES) ON SALE OF     
         INVESTMENTS                                          -       17,292         -         (6,292)      37,093          423 
                                               
                                               
        UNREALIZED APPRECIATION                
         OF INVESTMENTS                                       -    2,170,773         -         59,851    1,010,900       31,117 
                                               
        CONTRIBUTIONS:                         
         EMPLOYEE                                       127,589      200,024         -        138,142      510,484      118,835 
         EMPLOYER                                         1,485      469,797         -          5,383       13,140        4,173 
                                               
        OTHER INCOME (EXPENSE)                                -       12,941         -              -            -            - 
                                               
        DEDUCTIONS:                            
         BENEFITS PAID                                  (38,599)    (169,136)    9,660        (65,418)    (295,346)      (3,044)
         LOAN REPAYMENTS/(ADVANCES)                           -            -    43,352              -            -            - 
         ADMINISTRATIVE EXPENSES                              -            -    (1,305)             -            -            - 
         NET INTERFUND INVESTMENT REDIRECTION           (26,846)     401,742   (46,120)        19,689        5,932      (59,783)
                                                      ---------------------------------------------------------------------------
                                               
        NET INCREASE (DECREASE)                         113,333    3,103,883    19,862        222,299    1,518,574      101,913  
                                               
        PLAN EQUITY AT                         
         BEGINNING OF PERIOD                            860,578    2,560,565   111,606      1,034,936    3,417,071      211,763  
                                                      ---------------------------------------------------------------------------
                                               
        PLAN EQUITY AT                         
         END OF PERIOD                                 $973,911   $5,664,448  $131,468     $1,257,235   $4,935,645     $313,676  
                                                      ===========================================================================
<CAPTION> 


                                                        -----------------------------------------------      
                                                                                                             
                                                         COREFUND                                            
                                                          GROWTH         COREFUND                            
                                                          EQUITY       CONTRIBUTION                          
                                                         SERIES A      /DISTRIBUTION          TOTAL          
                                                        -----------------------------------------------      
        <S>                                              <C>           <C>                    <C>            
        INTEREST & OTHER INCOME                           $41,541               $686          $424,163       
                                                                                                             
        REALIZED GAINS (LOSSES) ON SALE OF                                                                   
         INVESTMENTS                                        8,744                  -            57,260       
                                                                                                             
                                                                                                             
        UNREALIZED APPRECIATION                                                                              
         OF INVESTMENTS                                   212,414                  -         3,485,055       
                                                                                                             
        CONTRIBUTIONS:                                                                                       
         EMPLOYEE                                         369,950                  -         1,465,024       
         EMPLOYER                                          17,296                  -           511,274       
                                                                                                             
        OTHER INCOME (EXPENSE)                                  -             (3,279)          (22,338)      
                                                                                                             
        DEDUCTIONS:                                                                                          
         BENEFITS PAID                                    (71,211)            (4,226)         (637,320)      
         LOAN REPAYMENTS/(ADVANCES)                             -                  -            43,352       
         ADMINISTRATIVE EXPENSES                                -                  -            (1,305)      
         NET  INTERFUND INVESTMENT REDIRECTION           (300,510)             5,896                 -       
                                                        -----------------------------------------------      
                                                                                                             
        NET INCREASE (DECREASE)                           278,224            (32,923)        5,325,165       
                                                                                                             
        PLAN EQUITY AT                                                                                       
         BEGINNING OF PERIOD                              598,478             51,259         8,846,256       
                                                        -----------------------------------------------      
                                                                                                             
        PLAN EQUITY AT                                                                                       
         END OF PERIOD                                   $876,702            $18,336       $14,171,421       
                                                        ===============================================      
</TABLE> 

                                      16
<PAGE>
                 CENTOCOR QUALIFIED SAVINGS AND RETIREMENT PLAN

                          NOTES TO FINANCIAL STATEMENTS
<TABLE> 
<CAPTION> 
Note 10      Allocation of Plan Income and Changes in Plan Equity to Investment Programs
             ---------------------------------------------------------------------------

                                                                        Year ended December 31, 1994
                                            ---------------------------------------------------------------------------------------
                                                                                                    COREFUND            COREFUND
                                               COREFUND                                 INTERMEDIATE         EQUITY       INTER-   
                                               TREASURY       CENTOCOR                      BOND             INDEX       NATIONAL  
                                               RESERVE         COMMON          LOAN         FUND              FUND        GROWTH   
                                               SERIES A        STOCK           FUND       SERIES A          SERIES A     SERIES A  
                                            ---------------------------------------------------------------------------------------
<S>                                            <C>               <C>        <C>             <C>           <C>               <C>    
     INTEREST & OTHER INCOME                   $32,944           $239       $10,209         $57,853         $91,613          $927   

     REALIZED GAINS (LOSSES) ON SALE OF
      INVESTMENTS                                    -         (2,179)            -         (10,571)        188,011           (6)  


     UNREALIZED APPRECIATION
      (DEPRECIATION) OF
      INVESTMENTS                                    -        666,999             -         (59,799)       (266,069)      (1,547)  

     CONTRIBUTIONS:
      EMPLOYEE                                 105,291        187,101             -         150,442         436,173       19,772   
      EMPLOYER                                   4,503        511,668             -           5,144           7,773       10,032   
     OTHER INCOME (EXPENSE)                          -        (83,794)            -               -               -            -   

     DEDUCTIONS:
      BENEFITS PAID                           (219,865)      (128,790)      (23,213)       (250,918)       (698,638)           -   
      TRANSFERS TO RELATED PARTY                     -              -             -               -               -            -   
      LOAN REPAYMENTS/(ADVANCES)                     -              -       (80,319)              -               -            -   
      ADMINISTRATIVE EXPENSES                        -              -        (1,963)              -               -            -   
      NET INTERFUND INVESTMENT REDIRECTION      32,333       (226,611)       92,165        (183,455)        (67,623)     182,585   
                                            ---------------------------------------------------------------------------------------

     NET INCREASE (DECREASE)                   (44,794)       924,633        (3,121)       (291,304)       (308,760)     211,763   

     PLAN EQUITY AT
      BEGINNING OF PERIOD                      905,372      1,635,932       114,727       1,326,240       3,725,831            -   
                                            ---------------------------------------------------------------------------------------

     PLAN EQUITY AT
      END OF PERIOD                           $860,578     $2,560,565      $111,606      $1,034,936      $3,417,071     $211,763   
                                            =======================================================================================
</TABLE>  
<TABLE> 
<CAPTION> 
                                                         Year ended December 31, 1994
                                             --------------------------------------------------    
                                                   COREFUND                                        
                                                    GROWTH         COREFUND                        
                                                    EQUITY       CONTRIBUTION                      
                                                   SERIES A     /DISTRIBUTION         TOTAL        
                                             --------------------------------------------------    
                                                                                                   
     <S>                                            <C>                 <C>         <C>            
     INTEREST & OTHER INCOME                        $2,227              $950        $196,962       
                                                                                                   
     REALIZED GAINS (LOSSES) ON SALE OF                                                            
      INVESTMENTS                                   (1,642)                -         173,613       
                                                                                                   
     UNREALIZED APPRECIATION                                                                       
      (DEPRECIATION) OF                                                                            
      INVESTMENTS                                  (13,130)                -         326,454       
                                                                                                   
     CONTRIBUTIONS:                                                                                
      EMPLOYEE                                     441,409                 -       1,340,188       
      EMPLOYER                                      10,678                 -         549,798       
     OTHER INCOME (EXPENSE)                              -            43,048         (40,746)      
                                                                                                   
     DEDUCTIONS:                                                                                   
      BENEFITS PAID                                (11,670)            7,261      (1,325,833)      
      TRANSFERS TO RELATED PARTY                         -                 -               -       
      LOAN REPAYMENTS/(ADVANCES)                         -                 -         (80,319)      
      ADMINISTRATIVE EXPENSES                            -                 -          (1,963)      
      NET INTERFUND INVESTMENT REDIRECTION         170,606                 -               -       
                                             ------------------------------------------------      
                                                                                                   
     NET INCREASE (DECREASE)                       598,478            51,259       1,138,154       
                                                                                                   
     PLAN EQUITY AT                                                                                
      BEGINNING OF PERIOD                                -                 -       7,708,102       
                                             ------------------------------------------------      
                                                                                                   
     PLAN EQUITY AT                                                                                
      END OF PERIOD                               $598,478           $51,259      $8,846,256       
                                             ================================================      
</TABLE> 
                                      17

<PAGE>

                                   CENTOCOR
                     QUALIFIED SAVINGS AND RETIREMENT PLAN
          ITEM 27a - SCHEDULE OF ASSETS HELD FOR INVESTMENT PURPOSES
                         YEAR ENDED DECEMBER 31, 1996


<TABLE> 
<CAPTION> 
Description of Assets:                    Number of Shares              Cost             Market
- ----------------------                    ----------------              ----             ------
<S>                                       <C>                       <C>               <C>  
Centocor Common Stock                              122,665           $2,014,233        $4,385,274
                                                         
CoreFund Treasury                                        
     Reserve Series A                              958,949              958,949           958,949
                                                         
CoreFund Intermediate                                    
     Bond Fund Series A                            116,282            1,153,285         1,146,541
                                                         
CoreFund Equity Index                                    
     Fund Series  A                                217,813            4,972,137         6,815,384
                                                         
CoreFund International                                   
     Growth Fund Series A                           49,731              646,438           650,973
                                                         
CoreFund Growth                                          
     Equity Fund Series A                          178,230            2,106,668         2,395,407
                                                         
Twentieth Century Vista Fund                        33,561              520,755           486,977

<CAPTION> 

                                        Number of Participants          Cost             Market
                                        ----------------------          ----             ------
<S>                                       <C>                       <C>               <C>  
Loans from participants                                 33             $178,434          $178,434
</TABLE> 

                                      18
<PAGE>

                                   CENTOCOR
                     QUALIFIED SAVINGS AND RETIREMENT PLAN
                ITEM 27d - SCHEDULE OF REPORTABLE TRANSACTIONS
                         YEAR ENDED DECEMBER 31, 1996
<TABLE> 
<CAPTION> 

                                         Purchases                                          Sales
                                   ---------------------           ---------------------------------------------------------
                                   Shares or                       Shares or                                           Net
Description of Assets              Par Value       Cost            Par Value       Proceeds         Cost       Gain / (Loss)
- ---------------------              ---------       ----            ---------       --------         ----       -------------
<S>                                <C>          <C>                <C>          <C>            <C>             <C>  

Centocor Common Stock                33,951     $816,458            63,016      $2,045,311     $1,084,489         $960,822

CoreFund Treasury
     Reserve Series A               266,980      266,980           282,276         282,276        282,276                -

CoreFund Intermediate
     Bond Fund Series A              20,604      203,250            17,283         171,328        172,483           (1,155)

CoreFund Equity Index
     Fund Series  A                  52,008    1,438,139            24,683         689,234        531,868          157,366

CoreFund International
     Growth Fund Series A            40,243      548,834            19,847         273,208        254,481           18,727

CoreFund Growth
     Equity Fund Series A            88,972    1,186,359            14,695         213,467        166,310           47,157

Twentieth Century Vista Fund         35,848      555,163             2,287          34,346         34,408              (62)

CoreFund Liquidity Fund           3,316,634    3,316,634         3,314,648       3,314,648      3,314,648                -
</TABLE> 

                                      19
<PAGE>
 
                                  SIGNATURES


    Pursuant to the requirements of the Securities Exchange Act of 1934, the
    Board of Directors has duly caused this Annual Report to be signed by the
    undersigned thereunto duly authorized.



                                        CENTOCOR QUALIFIED SAVINGS
                                        AND RETIREMENT PLAN



    June 4, 1997                        By:/s/ David P. Holveck
                                           --------------------
                                           David P. Holveck
                                           President and Chief Executive Officer

<PAGE>
 
                        Consent of Independent Auditors

    The Board of Directors
    Centocor, Inc.:

    We consent to incorporation by reference in Registration Statement Nos. 33-
    00167 and 33-16285 on Form S-8 of Centocor, Inc. of our report dated June 4,
    1997, relating to the statements of net assets available for plan benefits
    of the Centocor Qualified Savings and Retirement Plan as of December 31,
    1996 and 1995, and the related statements of changes in net assets available
    for plan benefits for each of the years in the three-year period ended
    December 31, 1996, which report appears in the December 31, 1996 annual
    report on Form 11-K of the Centocor Qualified Savings and Retirement Plan.



    KPMG Peat Marwick LLP



    Philadelphia, Pennsylvania
    June 4, 1997


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