ALZA TTS RESEARCH PARTNERS LTD
SC 14D1/A, 1997-12-19
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
 
                            ------------------------
 
                                 SCHEDULE 14D-1
 
              TENDER OFFER STATEMENT PURSUANT TO SECTION 14(D)(1)
                     OF THE SECURITIES EXCHANGE ACT OF 1934
 
   
                                AMENDMENT NO. 1
    
 
                        ALZA TTS RESEARCH PARTNERS, LTD.
                           (Name of subject company)
 
                              PHARMAINVEST, L.L.C.
                        PHARMACEUTICAL ROYALTIES, L.L.C.
                    PHARMACEUTICAL ROYALTY INVESTMENTS LTD.
                        PHARMACEUTICAL PARTNERS, L.L.C.
                                    (Bidder)
 
                     UNITS OF LIMITED PARTNERSHIP INTEREST
                         (Title of class of securities)
 
                                      NONE
                                 (CUSIP Number)
 
                            ------------------------
 
                          PABLO LEGORRETA, DAVE MADDEN
                              PHARMAINVEST, L.L.C.
                           70 E. 55th St., 23rd Floor
                               New York, NY 10022
                                 (800) 600-1450
 
                            ------------------------
 
   
                                   COPIES TO:
                             F. GEORGE DAVITT, ESQ.
                        TESTA, HURWITZ & THIBEAULT, LLP
                               HIGH STREET TOWER
                                125 HIGH STREET
                                BOSTON, MA 02110
    
 
                            ------------------------
 
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    This Amendment No. 1 amends and supplements the Tender Offer Statement on
Schedule 14D-1 as filed by PharmaInvest, L.L.C., a Delaware limited liability
company (the "Purchaser") on behalf of Pharmaceutical Royalties, L.L.C., a
Delaware limited liability company, and Pharmaceutical Royalty Investments Ltd.,
a Bermuda company (collectively the "Funds"), and on behalf of Pharmaceutical
Partners, L.L.C., relating to the offer by Purchaser to purchase outstanding
Units of Limited Partnership Interest (the "Units"), of ALZA TTS Research
Partners, Ltd. (the "Partnership"), a California limited partnership, at $12,000
per Unit, net to the seller in cash, on the terms and subject to the conditions
set forth in the Offer to Purchase, dated November 20, 1997 (the "Offer to
Purchase"), and in the related Letter of Transmittal and any amendments or
supplements thereto, copies of which are attached hereto as Exhibits (a)(1) and
(a)(2), respectively (which collectively constitute the "Offer").
    
 
   
    As of 5:00 p.m., Eastern Standard Time on Thursday, December 18, 1997,
approximately 13 Units have been tendered in the Offer.
    
 
   
    The Expiration Date of the Offer is hereby amended so that the Offer will
expire at 12:00 midnight, Eastern Standard Time on January 23, 1997.
    
 
   
ITEM 11. MATERIAL TO BE FILED AS EXHIBITS
    
 
   
    Item 11 is hereby amended as follows:
    
 
   
      (a)(4) Press Release dated November 21, 1997.
    
 
   
      (a)(5) Press Release dated December 19, 1997.
    
 
                                       2
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                                   SIGNATURES
 
    After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
 
   
Dated: December 19, 1997
    
 
   
<TABLE>
<S>                             <C>  <C>
                                PHARMAINVEST, L.L.C.
 
                                By:  /s/ PABLO LEGORRETA
                                     -----------------------------------------
 
                                Title: Managing Member of
                                Pharmaceutical Partners, L.L.C., the Manager
                                ---------------------------------------------
 
                                PHARMACEUTICAL ROYALTIES, L.L.C.
 
                                By:  /s/ PABLO LEGORRETA
                                     -----------------------------------------
 
                                Title: Managing Member of
                                Pharmaceutical Partners, L.L.C., the Manager
                                ---------------------------------------------
 
                                PHARMACEUTICAL ROYALTY
                                INVESTMENTS LTD.
 
                                By:  /s/ PABLO LEGORRETA
                                     -----------------------------------------
 
                                Title: Managing Member of
                                Pharmaceutical Partners, L.L.C., the Manager
                                ---------------------------------------------
 
                                PHARMACEUTICAL PARTNERS, L.L.C.
 
                                By:  /s/ PABLO LEGORRETA
                                     -----------------------------------------
 
                                Title: Managing Member
                                ---------------------------------------------
</TABLE>
    
 
                                       3
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                                 EXHIBIT INDEX
 
   
<TABLE>
<CAPTION>
 EXHIBIT                                                  DESCRIPTION
- ---------  ---------------------------------------------------------------------------------------------------------
<S>        <C>
(a)(4)     Press Release dated November 21, 1997
(a)(5)     Press Release dated December 19, 1997
</TABLE>
    

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                                                    Exhibit 99(a)(4)

                 PHARMAINVEST, L.L.C. ANNOUNCES TENDER OFFER

     NEW YORK, NY (Business Wire) -- Nov. 21, 1997 -- PharmaInvest, L.L.C. 
announced it has commenced a tender offer for up to 1,400 units of limited 
partnership interest of ALZA TTS Research Partners, Ltd. Details of the 
tender offer have been filed with the U.S. Securities and Exchange Commission 
and have been mailed to holders of the units. PharmaInvest will pay $12,000 
for each unit of limited partnership interest. The tender offer will expire 
December 19, 1997 unless extended.

     Copies of the tender offer materials can be obtained from MacKenzie 
Partners, Inc. at (800) 322-2885.


<PAGE>


                      PHARMAINVEST, L.L.C. EXTENDS TENDER OFFER
                                           
         NEW YORK, NEW YORK (December 19, 1997).......PharmaInvest, L.L.C. has
announced that its offer to purchase up to 1,400 of the outstanding units of
limited partnership interest of ALZA TTS Research Partners, Ltd. has been
extended and is now scheduled to expire at 12:00 Midnight (Eastern Standard
Time) on January 23, 1997. As of 5:00 p.m. on December 18, 1997, approximately
13 Units had been tendered and not withdrawn.  

    For additional information, contact MacKenzie Partners, Inc., the
Information Agent, at (800) 322-2885.





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