APPLIED MICRO CIRCUITS CORP
424B3, 1999-11-17
SEMICONDUCTORS & RELATED DEVICES
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<PAGE>

                                                      Pursuant to Rule 424(b)(3)
                                                              File No. 333-76185

                            SUPPLEMENT TO PROSPECTUS
                              DATED APRIL 15, 1999


                       APPLIED MICRO CIRCUITS CORPORATION

                  ____________________________________________


     The Prospectus, dated April 15, 1999, as declared effective on April 16,
1999, is hereby supplemented as follows to restate, in its entirety, the
"Selling Stockholders" section on pages 20-22 of the Prospectus.

                              SELLING STOCKHOLDERS

     The following table sets forth certain information as of October 31, 1999
with respect to the selling stockholders.  The following table assumes that the
selling stockholders sell all of the shares offered by this prospectus.  In
addition, the following table shows the number of shares beneficially owned
after taking into effect a two-for-one stock split declared effective as of
September 2, 1999.  We are unable to determine the exact number of shares that
actually have been or will be sold.

     The number and percentage of shares beneficially owned is based on a total
of 53,951,411 shares standing as of October 31, 1999 determined in accordance
with Rule 13d-3 of the Exchange Act.  The information is not necessarily
indicative of beneficial ownership for any other purpose.  Under Rule 13d-3,
beneficial ownership includes any shares as to which an individual has sole or
shares voting power or investment power, and also includes shares which an
individual has the right to acquire within 60 days of October 31, 1999 through
the exercise of any stock option or other right.  Unless otherwise indicated in
the footnotes, each person has sole voting and investment power (or shares such
powers with his or her spouse) with respect to the shares shown as beneficially
owned.

<TABLE>
<CAPTION>
                                         Shares Beneficially                             Shares Beneficially
                                          Owned Prior to the                               Owned After the
                                               Offering                                      Offering (2)
                                     -------------------------                       --------------------------
Selling Stockholders (1)                 Number       Percent     Shares Offered by      Number       Percent
                                                                   this Prospectus
- ---------------------------------------------------------------------------------------------------------------
<S>                                    <C>          <C>          <C>                   <C>          <C>
Ramakrishna Sudireddy............       643,872         1.2%            643,872              0           --
Gary Martin......................       557,634         1.0%            557,634              0           --
Gururaj Deshpande................       231,868          *              231,868              0           --
Charles Waite....................       147,692          *              147,692              0           --
</TABLE>

                                       1.
<PAGE>

<TABLE>
<S>                                     <C>             <C>             <C>                 <C>         <C>
Shahrukh Merchant....................   137,576         *               137,576             0           --
Christos Skalkos.....................   131,208         *               131,208             0           --
Steve Boulanger......................    80,726         *                80,726             0           --
John LoMedico........................   124,194         *               124,194             0           --
John Langevin........................    32,802         *                32,802             0           --
David Aronoff........................    11,908         *                11,908             0           --
Kurt Baty............................    43,763         *                43,763             0           --
Prabhu Goel..........................    59,640         *                59,640             0           --
Dennis Rainville.....................    11,928         *                11,928             0           --
Stephen Augusta......................    50,348         *                50,348             0           --
Nick Barry...........................     1,590         *                 1,590             0           --
Kathy L. Bechtel.....................    29,820         *                29,820             0           --
Ron Berry............................    15,904         *                15,904             0           --
Tony Candage.........................    55,664         *                55,664             0           --
William Carrigan.....................    53,706         *                53,706             0           --
Mark Donovan.........................    47,712         *                47,712             0           --
Arthur Handras.......................    15,904         *                15,904             0           --
Jeffery Long.........................    13,426         *                13,426             0           --
Jahangir Nakra.......................    15,744         *                15,744             0           --
Diana Ng.............................     8,746         *                 8,746             0           --
Sean Sweeney.........................    23,856         *                23,856             0           --
Robert MacCleod......................    27,832         *                27,832             0           --
Judy Sundue..........................     2,384         *                 2,384             0           --
Henry F. McCance.....................    33,414         *                33,414             0           --
McCance 1996 Family Trust
fbo Ellen Lee McCance non-exempt.....    29,756         *                29,756             0           --
</TABLE>

                                       2.
<PAGE>

<TABLE>
<S>                                     <C>         <C>                   <C>              <C>          <C>
Howard E. Cox, Jr....................       59,518         *                   59,518            0           --
David N. Strohm......................       14,878         *                   14,878            0           --
Mapache Investments L.P..............       44,640         *                   44,640            0           --
William W. Helman....................       59,518         *                   59,518            0           --
William S. Kaiser....................       59,518         *                   59,518            0           --
Roger L. Evans.......................       59,518         *                   59,518            0           --
Charles M. Hazard, Jr................       15,066         *                   15,066            0           --
Mary H. Murphy.......................        1,504         *                    1,504            0           --
Barbara P. Murray....................        3,010         *                    3,010            0           --
Clifford Partners....................       16,620         *                   16,620            0           --
Sherman Fairchild Foundation, Inc....       19,936         *                   19,936            0           --
Helen C. Alexander...................        2,880         *                    2,880            0           --
Emory A. Hamilton....................        2,880         *                    2,880            0           --
John D. Alexander, Jr................        2,880         *                    2,880            0           --
Caroline R. Alexander................        2,880         *                    2,880            0           --
Henrietta A. George..................        2,880         *                    2,880            0           --
Dorothy A. Maiz......................        2,880         *                    2,880            0           --
Ashbourne Partners III, LP...........       17,678         *                   17,678            0           --
Springcreek Corporation..............          420         *                      420            0           --
Key Trust Company of Ohio, N.A.,
Theodore T. Jones and
Latham W. Marley, III, Trustees
Trust f/b/o Alison C. Jones u/a
established by Edith W. Corning dtd
7/25/46 as amended...................       12,562        *                    12,562            0           --
</TABLE>

                                       3.
<PAGE>

<TABLE>
<S>                                     <C>            <C>              <C>                <C>           <C>
Key Trust Company of Ohio, N.A.,
Edson Spencer, Jr. and David
Warshawsky, Trustees
Trust f/b/o Samuel D. Long u/a
established by Edith W. Corning dtd
7/25/46 as amended...................        6,186        *                     6,186            0           --
Key Trust Company of Ohio, N.A.,
Edson Spencer, Jr. and David
Warshawsky, Trustees
Trust f/b/o Maud-Alison Long u/a
established by Edith W. Corning dtd
7/25/46 as amended...................        6,186        *                     6,186            0           --
Key Trust Company of Ohio, N.A.,
Edson Spencer, Jr. and David
Warshawsky, Trustees
Trust f/b/o Henry H. Corning u/a
established by Edith W. Corning dtd
7/25/46 as amended...................       13,746        *                    13,746            0           --
Key Trust Company of Ohio, N.A.,
James Bastian, Peter W. Nordell,
Trustees Alison C. Jones Posterity...        1,394        *                     1,394            0           --
Henry H. Corning, Trustee
Ellen Long Family Trust..............        1,374        *                     1,374            0           --
Dartmouth College....................       31,908        *                    31,908            0           --
Field Venture Partners...............       66,472        *                    66,472            0           --
Gothic Corporation...................       95,710        *                    95,710            0           --
Poduska Family Limited Partnership
TLP..................................        2,662        *                     2,662            0           --
Michael J. Birck.....................        1,596        *                     1,596            0           --
Robert E. Cook.......................        2,662        *                     2,662            0           --
The Northern Trust Company,Trustee
The Daisy Trust......................        2,662        *                     2,662            0           --
Gabriel Schmergel....................        2,662        *                     2,662            0           --
Thomas H. Bruggere...................        1,328        *                     1,328            0           --
John W. Brown Trust..................        2,126        *                     2,126            0           --
</TABLE>

                                       4.
<PAGE>

<TABLE>
<S>                                     <C>         <C>              <C>                     <C>          <C>
Saturn & Co., Nominee for Grossman
Family Partnership...................        2,126          *                   2,126            0           --
Peter Preuss.........................        2,662          *                   2,662            0           --
William C. O'Neil, Jr................        1,328          *                   1,328            0           --
Curt A. Rawley.......................        1,328          *                   1,328            0           --
William J. Warner....................        2,126          *                   2,126            0           --
John M. Connolly.....................          534          *                     534            0           --
Mone Anathan, III....................        2,662          *                   2,662            0           --
Samuel J. Gerson.....................        2,662          *                   2,662            0           --
Douglas P. Colbeth...................        1,328          *                   1,328            0           --
David C. Mahoney.....................        1,328          *                   1,328            0           --
Tadeusz Witkowicz....................        2,662          *                   2,662            0           --
James A. Perakis.....................        1,596          *                   1,596            0           --
Joshua Boger.........................        1,328          *                   1,328            0           --
Malcolm L. Gefter....................        1,328          *                   1,328            0           --
Dirk I. Gates........................        1,328          *                   1,328            0           --
Safi U. Qureshey, Trustee
Safi U. Qureshey Family Turst dtd
5/21/84..............................        1,328          *                   1,328            0           --
Goel Family Partnership..............        2,662          *                   2,662            0           --
William M. Gibson....................        1,328          *                   1,328            0           --
Alexander V. d'Arbeloff..............        1,278          *                   1,278            0           --
Irwin F. Smith.......................        2,662          *                   2,662            0           --
Borra Investment Partners L.P........        1,328          *                   1,328            0           --
Louis & Jolene Cole 1988 Rev Trust
dtd 11/7/88..........................        1,328          *                   1,328            0           --
Gary B. Eichhorn.....................        1,328          *                   1,328            0           --
</TABLE>

                                       5.
<PAGE>

<TABLE>
<S>                                    <C>          <C>             <C>                 <C>            <C>
Morleza Ejabat.......................        1,328         *                    1,328            0           --
Shikhar Ghosh........................        1,328         *                    1,328            0           --
David K. Gifford.....................        1,328         *                    1,328            0           --
Steven & Florence Goldby Trust.......        1,328         *                    1,328            0           --
Robert M. Halperin...................        1,328         *                    1,328            0           --
Frank A. Ingari......................        1,328         *                    1,328            0           --
D. R. L. Jones.......................        1,328         *                    1,328            0           --
Thomas D. & Deanna L. Jones,
Trustees of Jones 1995 Family Trust
8/24/95..............................        1,328         *                    1,328            0           --
Peter J. Kight.......................        1,328         *                    1,328            0           --
Tim Krauskopf........................        1,066         *                    1,066            0           --
Eric S. Lander.......................        1,328         *                    1,328            0           --
John B. Landry.......................        1,328         *                    1,328            0           --
Mark J. Levin........................        1,328         *                    1,328            0           --
Joseph A. Liemandt...................          534         *                      534            0           --
Shaun M. McConnon....................        1,328         *                    1,328            0           --
Miller Family Partnership LP.........        6,382         *                    6,382            0           --
Brian D. Owen........................          534         *                      534            0           --
Marcia J. Radosevich.................        1,328         *                    1,328            0           --
Jonathan Reeves......................        1,328         *                    1,328            0           --
Robert J. Ryan.......................        1,328         *                    1,328            0           --
Carols A. Saladrigas.................        1,328         *                    1,328            0           --
Jose M. Sanchez......................        1,328         *                    1,328            0           --
Amit Shah............................          534         *                      534            0           --
Martin J. Sprinzen...................        1,328         *                    1,328            0           --
</TABLE>

                                       6.
<PAGE>

<TABLE>
<S>                                    <C>          <C>              <C>                  <C>          <C>
Robert A. Steinkrauss................        1,328         *                    1,328            0           --
Michael F. Tyrrell...................        1,328         *                    1,328            0           --
Robert A. Lawrence...................          530         *                      530            0           --
Hill and Company.....................       15,558         *                   15,558            0           --
Neil L. Thompson.....................          532         *                      532            0           --
Barr Foundation......................       42,540         *                   42,540            0           --
Freschette Fund, Inc.................       25,264         *                   25,264            0           --
PCW Fund, Inc........................       10,638         *                   10,638            0           --
Scaup & Co...........................          658         *                      658            0           --
Thomas W. Keesee, Jr.................        5,314         *                    5,314            0           --
Freya Fanning & Co., Nominee
Edward H. Ladd, Trustee u/a/d
12/15/78.............................       11,034         *                   11,034            0           --
A. A. Welsh & Co.....................       50,672         *                   50,672            0           --
Atwell & Co..........................          510         *                      510            0           --
Massachusetts Institute of Technology       95,710         *                   95,710            0           --
Fleet National Bank, Trustee
Orchard Trust U/A/D/ 5/1/73..........        5,314         *                    5,314            0           --
Harvard Private Capital Holdings,
Inc..................................       95,710         *                   95,710            0           --
Polk-Lillard Limited Partnership
John S. Lillard Trust 12/31/70.......        6,380         *                    6,380            0           --
Lillard Investment Trust.............        2,128         *                    2,128            0           --
Lillard Partners.....................       10,636         *                   10,636            0           --
Louis F. Polk, Jr. Trustee of Louis
F. Polk, Sr. Rev Trust dtd 1/22/69...       19,604         *                   19,604            0           --
Louis F. Polk, Jr. Marital Trust.....        8,510         *                    8,510            0           --
</TABLE>

                                       7.
<PAGE>

<TABLE>
<S>                                    <C>          <C>               <C>              <C>             <C>
Louis F. Polk, Jr. IRRV
Grandchildren TST....................        4,252          *                   4,252            0           --
Polk Family Partnership..............       10,636          *                  10,636            0           --
Board of Trustees of the Leland
Stanford Junior University...........       95,710          *                  95,710            0           --
Standish Ventures III L.P............        9,306          *                   9,306            0           --
Julia L. Thorne Trust u/a 9/29/65
Edwin Thorne, Sole Trustee...........       15,950          *                  15,950            0           --
Edwin Thorne.........................        2,654          *                   2,654            0           --
Edwin Thorne, Jr.....................        2,130          *                   2,130            0           --
Gordon G. Thorne.....................        3,068          *                   3,068            0           --
Gordon Thorne's Alaska Trust.........          338          *                     338            0           --
Brinkley S. Thorne...................        3,832          *                   3,832            0           --
Deep Powder Trust....................          424          *                     424            0           --
Snowball Trust.......................        4,256          *                   4,256            0           --
Wink Thorne..........................        1,064          *                   1,064            0           --
Jennifer Hislop......................          424          *                     424            0           --
Benjamin Thorne......................          424          *                     424            0           --
Brooks Walker, Jr. Trustee
M.K. Walker Trust dtd 9/1/89.........        5,314          *                   5,314            0           --
Brooks Walker Jr. TTEE
Brooks Walker Jr. Rev. Tr u/a/d
6/24/96..............................        5,336          *                   5,336            0           --
Wellington S. Henderson, Trustee
Wellington S. Henderson, Jr.
Rev. Trust dtd 3/9/93................        1,062          *                   1,062            0           --
Harriett W. Henderson Trust
u/a/dtd August 14, 1973 FBO of
Charles C. Henderson.................          530          *                     530            0           --
</TABLE>

                                       8.
<PAGE>

<TABLE>
<S>                                  <C>           <C>              <C>                 <C>           <C>
Brooks Walker III, Trustee
Walker Trust dtd 12/24/74
fbo Kirby Walker.....................        1,770         *                    1,770            0           --
Brooks Walker III, Trustee
Walker Trust dtd 12/24/74
fbo Leslie Walker....................        1,770         *                    1,770            0           --
Brooks Walker III, Trustee
Walker Trust dtd 12/24/74............        1,770         *                    1,770            0           --
Harriett W. Henderson Trust
u/a/d August 14, 1973 FBO
James A. Henderson...................          530         *                      530            0           --
Harriet W. Henderson Trust
u/a/dtd August 14, 1973 FBO of
Joan H. Henderson....................          530         *                      530            0           --
Harriet W. Henderson Trust
u/a/dtd August 14, 1973 FBO of
Elena D. Henderson...................          530         *                      530            0           --
Harriet W. Henderson Trust
u/a/dtd August 14, 1973 FBO of
Mark W. Henderson....................          530         *                      530            0           --
Freya Fanning & Co., as Nominee for
David Ayer...........................          138         *                      138            0           --
Susanna B. Place, Trustee
SMBP Trust u/a/d 2/28/85.............        1,362         *                    1,362            0           --
Freya Fanning & Co., as Nominee for
Essex LP IX..........................       53,700         *                   53,700            0           --
SeaFed L.P...........................          932         *                      932            0           --
David E. Place.......................        1,362         *                    1,362            0           --
Richard M. Place, Daniel S. Gregory
and Richard N. Hoehn Trustees u/i
Place/Greylock Trust dated as of
12/27/1978...........................        2,596         *                    2,596            0           --
Thomas J. Watson, III................        5,318         *                    5,318            0           --
Daniel Moseley, Trustee u/a
Blodgett 1989 Family Trust...........        1,648         *                    1,648            0           --
</TABLE>

                                       9.
<PAGE>

<TABLE>
<S>                                    <C>          <C>              <C>                 <C>          <C>
Helen W. Blodgett 1983 Trust.........        1,274         *                    1,274            0           --
Miriam A. Gilpatric..................        3,320         *                    3,320            0           --
John B. Jessup, Trustee
Julia Thorne 1965 Trust 9/29/65......        6,650         *                    6,650            0           --
Morgan Guaranty Trust f/b/o
J. Stetson dated 5/29/57.............        1,330         *                    1,330            0           --
Yale University......................       95,710         *                   95,710            0           --
McCance Family Limited
Partnership..........................        2,658         *                    2,658            0           --
Henry F. McCance, Alison J. McCance
& Keith S. Jennings u/i dtd 12/22/93
Trustees of McCance Family Trust
f/b/o Ellen Lee McCance..............        1,064         *                    1,064            0           --
Henry F. McCance, Alison J. McCance
& Keith S. Jennings u/I dtd 12/22/93
Trustees of McCance Family Trust
f/b/o Elizabeth Ferguson McCance.....        1,064         *                    1,064            0           --
Thomas McCance, Jr. & Keith S.
Jennings Trustees
u/a Ellen L. McCance Tr 11/26/97.....        1,596         *                    1,596            0           --
Elizabeth McCance....................        1,596         *                    1,596            0           --
William S. Kaiser....................        2,658         *                    2,658            0           --
Arthur Hughes, Trustee u/i/d 2/2/94
Helman Children's Trust
fbo William Wilson Helman V..........          532         *                      532            0           --
Robert N. Shapiro, Trustee
Henderson Family 1996 Trust for
Children & More Remote Issue.........        2,658         *                    2,658            0           --
Charles P. and Angela Waite..........        1,328         *                    1,328            0           --
William Elfers.......................        2,658         *                    2,658            0           --
Roger L. Evans.......................       20,736         *                   20,736            0           --
</TABLE>

                                      10.
<PAGE>

<TABLE>
<S>                                        <C>              <C>               <C>                <C>         <C>
Stephen Bochner, Trustee of
Evans Children's Trust u/a/d
12/20/93.............................          532          *                     532            0           --
Arthur Hughes, Trustee u/i/d 2/2/94
Helman Children's Trust
fbo Beatrice Page Helman.............          532          *                     532            0           --
Charles M. Hazard, Jr................          212          *                     212            0           --
The Hazard Family Trust fbo Whitney
Keene Hazard, Katherine Hazard
Flynn, TTEE..........................          320          *                     320            0           --
The Hazard Family Trust fbo C.
Michael Hazard III, Katherine
Hazard Flynn, TTEE...................          320          *                     320            0           --
William W. Helman....................        1,596          *                   1,596            0           --
Matrix V Management Co., L.L.C.......      354,130          *                 354,130            0           --
Trustees of Amherst College..........       12,694          *                  12,694            0           --
Bechtle Revocable Trust..............        3,626          *                   3,626            0           --
Friedrich Bechtle....................        3,626          *                   3,626            0           --
Berea College........................       21,764          *                  21,764            0           --
Brinson Trust Company as Trustee of
Brinson Partnership Fund Trust -
1997 Primary Fund....................       21,764          *                  21,764            0           --
Evangelical Lutheran Church in
American Board of Pensions...........        1,452          *                   1,452            0           --
Morgan Stanley Trust Company as
Custodian to Brinson Partnership
Fund - 1997 Primary Fund, L.P........       10,156          *                  10,156            0           --
State Street Bank & Trust Company as
Custodian for EDS Retirement Plan
Trust................................       32,644          *                  32,644            0           --
State Street Bank & Trust Company as
Custodian for Orange County
Employees Retirement System..........       10,882          *                  10,882            0           --
</TABLE>

                                      11.
<PAGE>

<TABLE>
<S>                                        <C>               <C>              <C>                <C>         <C>
State Universities Retirement System.....   26,840           *                 26,840            0           --
The 1996 Brinson Partnership Fund
Offshore Series Company Ltd..............    5,802           *                  5,802            0           --
Virginia Retirement System...............   81,246           *                 81,246            0           --
The Church Pension Fund..................   90,676           *                 90,676            0           --
Crossroads 1997 Asset Allocation I,
L.P......................................   14,510           *                 14,510            0           --
Crossroads 1997 Asset Allocation II,
L.P......................................   13,782           *                 13,782            0           --
Crossroads Venture Capital I, L.P........    7,254           *                  7,254            0           --
Crossroads 1997 Venture Capital
Programme I, L.P.........................   11,606           *                 11,606            0           --
Trustees of Dartmouth College............   29,014           *                 29,014            0           --
Employees' Retirement Plan of Duke
University...............................   10,882           *                 10,882            0           --
Gothic Corporation.......................   54,406           *                 54,406            0           --
Marco F. Hellman Trust "B"...............    5,440           *                  5,440            0           --
FWH Associates...........................    5,440           *                  5,440            0           --
Phemus Corporation.......................   90,676           *                 90,676            0           --
HB-PGGM Fund II, L.P.....................   29,014           *                 29,014            0           --
Horsley Bridge Fund V, L.P...............  148,708           *                148,708            0           --
The Andrew W. Mellon Foundation..........   72,542           *                 72,542            0           --
Meridian International Investments
Limited..................................   21,764           *                 21,764            0           --
The Regents of the University of
Michigan.................................   47,150           *                 47,150            0           --
Massachusetts Institute of Technology....   45,338           *                 45,338            0           --
Massachusetts Institute of
Technology Retirement Plan...............   45,338           *                 45,338            0           --
</TABLE>

                                      12.
<PAGE>

<TABLE>
<S>                                   <C>          <C>              <C>                  <C>           <C>
Bankers Trust Company as Custodian
for New Mexico State Investment
Council                                     15,958          *                  15,958            0           --
Kale & Co. A/C JD85                         72,542          *                  72,542            0           --
Williams College                            12,694                             12,694            0           --
Matrix V Entrepreneurs Fund, L.P.          159,040          *                 159,040            0           --
</TABLE>
_______________________
*Less than 1%

     (1)  This table is based upon information supplied to us by the selling
          stockholders.

     (2)  Assumes the sale of all of the shares that may be offered for resale
          for the account of the selling stockholders pursuant to this
          prospectus.

     Except as described below, none of the selling stockholders in the above
table has had any material relationship, other than as an employee or
consultant, with us or any of our predecessors or affiliates within the last
three years:

     .  Prior to the merger of Cimaron Communications Corporation with Applied
        Micro Circuits Corporation, pursuant to which Cimaron became our wholly-
        owned subsidiary, the following selling stockholders had the following
        material relationships with Cimaron:

        .  Ramakrishna Sudireddy, President and Chief Executive Officer,
           Director;
        .  Gary Martin, Vice President and Chief Technical Officer, Director;
        .  Charles Waite, Vice President of Operations;
        .  Steve Boulanger, Vice President and Chief Financial Officer;
        .  John LoMedico, Vice President of Sales and Marketing;
        .  Gururaj Deshpande, Director; and
        .  Matrix Partners V, L.P. and Matrix V Entrepreneurs Fund, L.P., owned
           more than 10% of the outstanding stock of Cimaron and Timothy
           Barrows, a general partner of both Matrix partnerships, was a
           director of Cimaron.

     Following the merger, Mr. Sudireddy became the Vice President, Cimaron and
Mr. Martin became the Vice President and Chief Technical Officer, Cimaron.

          The date of this Prospectus Supplement is November 17, 1999.

                                      13.


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