PHARMOS CORP
424B3, 1997-06-23
PHARMACEUTICAL PREPARATIONS
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                               PHARMOS CORPORATION
                               -------------------



                       10,000,000 SHARES OF COMMON STOCK,
                          $.03 PAR VALUE, TO BE SOLD BY
                            SELLING SECURITY HOLDERS

                     159,000 SHARES OF COMMON STOCK ISSUABLE
                  UPON EXERCISE OF WARRANTS TO PURCHASE SHARES
                     AT AN EXERCISE PRICE OF $1.75 PER SHARE

     This Prospectus covers the proposed offer and resale of up to 10,000,000
shares (the "Shares"), the amount of which is calculated based on a $0.60
conversion price, of common stock, par value $.03 ("Common Stock") of Pharmos
Corporation (the "Company") held by stockholders (the "Selling Stockholders")
who purchased 6,000 shares ($6,000,000 principal amount) of 5% Preferred Stock
(the "Series B Preferred Stock") convertible into such shares in a private
placement transaction in March 1997 (the "Private Placement Transaction"). The
Private Placement Transaction, in which the Company issued 6,000 shares of
Series B Preferred Stock to the Selling Stockholders for the principal amount of
$6,000,000, was completed on March 31, 1997 (the "Closing Date"). The preferred
shares can be converted by the Selling Stockholders as follows: up to 40% of
their initial investment after 90 days from the Closing Date, up to a cumulative
of 80% of their initial investment after 180 days from the Closing Date, and up
to a cumulative of 100% of their initial investment after 270 days from the
Closing Date, at between 80% to 83% of prevailing market prices at time of
conversion.

     This Prospectus also covers the offer and proposed sale by the Company of
up to (i) 159,000 shares of Common Stock issuable upon the exercise by the
holders thereof of warrants to purchase 159,000 shares (which amount may
increase solely to account for applicable anti-dilution adjustments, if any) at
an exercise price of $1.75 per share issued to the Selling Stockholders in
connection with the Private Placement Transaction. (All of the warrants set
forth above are hereinafter separately and collectively referred to as the
"Warrants" and the shares of Common Stock issuable upon the exercise of the
Warrants are hereinafter separately and collectively referred to as the "Warrant
Shares.")

     In connection with this offering, the Selling Stockholders and certain
holders of the Warrants who may be deemed to be "affiliates" of the Company, as
that term is defined under the Securities Act of 1933, as amended (the "Act"),
may be deemed to be an "underwriter," as that term is defined under the Act, of
the Shares or Warrant Shares offered hereby. It is anticipated that the Selling
Stockholders and such affiliates intend to sell the Shares or Warrant Shares
offered hereby from time to time for their own respective accounts in the open
market at the prices prevailing therein or in individually negotiated
transactions at such prices as may be agreed upon. Each Selling Stockholder and
such affiliate will bear all expenses with respect to the offering of the Shares
or Warrant Shares offered hereby by him except the costs of legal counsel and
costs associated with registering such shares under the Act and preparing and
printing this Prospectus.

     The net proceeds from Shares to be sold by the Selling Stockholders (and by
holders of Warrant Shares who exercise their Warrants) will inure entirely to
their benefit and not to


<PAGE>


that of the Company; however the Company will receive proceeds from the exercise
of the Warrants.

     The Company's Common Stock is traded on the over-the-counter market and is
quoted on the Nasdaq SmallCap Market under the symbol "PARS" The closing price
of the Company's Common Stock on June 16, 1997 was $1.97.


<PAGE>


THESE SECURITIES INVOLVE A HIGH DEGREE OF RISK AND SUBSTANTIAL DILUTION AS
DESCRIBED HEREIN (SEE "RISK FACTORS" AND "DILUTION").

THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION NOR HAS THE SECURITIES
AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION PASSED UPON THE
ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A
CRIMINAL OFFENSE.

                  The date of this Prospectus is June 20, 1997

<PAGE>


     The laws of many states provide exemptions from registration,  particularly
for sales of securities  by persons  other than issuers,  such as certain of the
Selling  Stockholders  and  holders of the  Warrants,  who do not have a control
relationship  with the issuer,  and for the subsequent resale of such securities
by purchasers  thereof.  Purchasers  hereunder  should consult with their broker
and/or attorney to determine whether applicable state laws permit such purchases
and resales by them.

     With  respect  to the  proposed  sale of the Shares  offered  hereby by the
Selling  Stockholders  and the sale of the Warrant  Shares by the  Company  upon
exercise  of the  Warrants,  the  Company  is  taking  steps to  register  these
securities or permit such sales  pursuant to exemption  from  registration  only
under the laws of California, Connecticut, Florida, Massachusetts, Michigan, New
Jersey, New York,  Pennsylvania and Texas.  Holders of Shares,  therefore,  must
sell their Shares  (through a  broker/dealer  or  otherwise),  either:  (i) to a
resident  of  one  of the  aforementioned  states  or to an  entity,  such  as a
broker/dealer  registered  in such state,  which may be exempt under  applicable
state laws, or (ii) pursuant to another applicable exemption. In such event, the
Company  will only  permit  the  transfer  of the Shares if its  transfer  agent
receives a certification from the holder that the sale was made to a resident of
one of the aforementioned  states or to a state registered  broker/dealer or the
Company receives an opinion of counsel, reasonably satisfactory to the Company's
counsel,  that the resale of the Shares is  otherwise  exempt from  registration
under applicable state law.

     With respect to the proposed sale of the Warrant Shares,  if holders of the
Warrants are not residents of the aforementioned states, the Company will not be
able to permit  them to exercise  Warrants  held by them,  unless  such  holders
obtain an opinion of counsel,  satisfactory to the Company's counsel,  that such
transaction is exempt from registration.  Under such  circumstances,  their only
alternatives  may be to sell their Warrants and/or Common Stock to a resident of
the aforementioned  states or to sell their Warrants and/or Warrant Shares to an
entity,  such as a registered  broker-dealer in such state,  which may be exempt
under applicable state laws.

     Holders of the Warrants  and/or  Warrant  Shares should  consult with their
broker and/or  attorney to determine what actions should be taken to comply with
the laws of their state with respect to any Warrants  and/or Warrant Shares held
by them and, specifically with respect to the Warrants,  ensure that such action
is taken well  prior to the  respective  expiration  dates of the  Warrants,  if
necessary.

     The  Company  will  furnish  to each  person  to whom  this  Prospectus  is
delivered,  upon written request, a copy of any or all of the documents referred
to by reference,  other than exhibits to such documents unless such exhibits are
specifically incorporated herein by reference.  Requests should be addressed to:
Mr. Gad Riesenfeld,  President and Chief Operating Officer, Pharmos Corporation,
2 Innovation Drive, Alachua, Florida 32615, (904) 462-1210.


<PAGE>


     NO  DEALER,  SALESMAN  OR  OTHER  PERSON  HAS BEEN  AUTHORIZED  TO GIVE ANY
INFORMATION  OR TO MAKE ANY  REPRESENTATION  OTHER THAN THOSE  CONTAINED IN THIS
PROSPECTUS.  ANY INFORMATION OR REPRESENTATION NOT HEREIN CONTAINED, IF GIVEN OR
MADE,  MUST NOT BE RELIED UPON AS HAVING BEEN  AUTHORIZED  BY THE COMPANY.  THIS
PROSPECTUS  DOES NOT  CONSTITUTE  AN OFFER OR  SOLICITATION  IN  RESPECT  OF THE
SECURITIES  IN ANY  JURISDICTION  IN WHICH SUCH OFFER OR  SOLICITATION  WOULD BE
UNLAWFUL. DELIVERY OF THIS PROSPECTUS SHALL NOT, UNDER ANY CIRCUMSTANCES, CREATE
ANY  IMPLICATION  THAT THERE HAS BEEN NO CHANGE IN THE  AFFAIRS  OF THE  COMPANY
SINCE THE DATE OF THIS PROSPECTUS.


<PAGE>


                             ADDITIONAL INFORMATION

     The Company has filed with the  Securities  and  Exchange  Commission,  450
Fifth Street, Washington, D.C. 20549, a Registration Statement on Form S-3 under
the Securities Act of 1933 with respect to the securities  offered hereby.  This
Prospectus filed as part of such Registration Statement does not contain all the
information set forth in, or annexed as exhibits to, the Registration Statement.
For further  information  pertaining to the  securities  offered  hereby and the
Company,  reference  is  made to the  Registration  Statement  and the  exhibits
thereto. The Registration Statement and exhibits thereto may be inspected at the
Headquarters  Office of the  Securities and Exchange  Commission  located at 450
Fifth Street,  N.W.,  Room 1024,  Washington,  D.C.  20549 and at certain of the
Commission's regional offices at the following addresses:  7 World Trade Center,
Suite 1300, New York, New York 10048;  Northwest Atrium Center, 500 West Madison
Street,  Suite 1400,  Chicago,  IL 60661.  Copies of this  material  also may be
obtained  from the Public  Reference  Section of the SEC,  at 450 Fifth  Street,
N.W., Room 1024, Washington,  D.C. at prescribed rates.  Electronic registration
statements made through the Electronic  Data  Gathering,  Analysis and Retrieval
System are publicly  available  through the Commission's  World Wide Web site at
http:\www.sec.gov.  The statements  contained in this Prospectus  concerning the
contents of any contract or document  referred to are not necessarily  complete,
and in each instance, reference is made to such contract or document filed as an
exhibit to the  Registration  Statement,  each statement  being qualified in all
respects by provisions  of such exhibit to which  reference is hereby made for a
full statement of the provisions thereof.


<PAGE>


                                   THE COMPANY

     The Company is engaged in the development of novel pharmaceuticals based on
innovative drug design technologies  targeting diseases of the eye,  principally
ocular inflammation, and the brain, principally stroke and head trauma.

     Its   leading   product,   Lotemax(TM),   is   a   proprietary   ophthalmic
anti-inflammatory  drug designed with the  Company's  proprietary  "site active"
concept  system  and  has  demonstrated  significant  efficacy  in a  series  of
completed  Phase III  clinical  trials and a uniquely  superior  safety  profile
compared to currently available ophthalmic  steroids.  The Company has submitted
its New Drug  Application  ("NDA")  for  Lotemax(TM)  to the U.S.  Food and Drug
Administration ("FDA").

     The  Company's  principal  executive  offices are  located at 2  Innovation
Drive, Alachua, Florida 32615, telephone (904) 462-1210.

                                  RISK FACTORS

     The Common  Stock  being  offered  hereby  involves a high  degree of risk.
Prospective  investors should  carefully  consider the following risk factors in
addition to other  information  contained in this  Prospectus,  in evaluating an
investment in the shares of Common Stock offered hereby.

Early Stage of Development; Technological Uncertainty

     The Company is at an early stage of  development.  Apart from  Lotemax(TM),
most of the  Company's  other  potential  products are early in the research and
development phase, and product revenues may not be realized from the sale of any
such  products  for at least  the next  several  years,  if at all.  Many of the
Company's  proposed products will require  significant  additional  research and
development efforts prior to any commercial use, including extensive preclinical
and clinical  testing as well as lengthy  regulatory  approval.  There can be no
assurance  that  the  Company's   research  and  development   efforts  will  be
successful,  that the  Company's  potential  products  will prove to be safe and
effective in clinical trials or that any commercially  successful  products will
ultimately be developed by the Company.

History of Operating Losses; Accumulated Deficit

     The  Company  has  experienced   significant  operating  losses  since  its
inception.  As of December 31, 1996, the Company had an  accumulated  deficit of
approximately $62 million. The Company expects to incur operating losses over at
least the next several years as the Company's  research and development  efforts
and preclinical and clinical testing activities continue.  The Company's ability
to achieve profitability depends in part upon its ability, alone or with others,
to  successfully  commercialize  and  receive  approval  on its  first  proposed
product,  to complete  development  of its other  proposed  products,  to obtain
required regulatory approvals and to manufacture and market such products.


                                        1

<PAGE>


Future Capital Needs; Uncertainty of Additional Financing

     The Company's operations to date have consumed substantial amounts of cash.
The development of the Company's  technology and potential products will require
a  commitment  of  substantial  funds to conduct  the costly and  time-consuming
research necessary to develop and optimize such technology,  and ultimately,  to
establish manufacturing and marketing capabilities. The Company's future capital
requirements  will  depend  on  many  factors,  including  continued  scientific
progress in the research and  development  of the Company's  technology and drug
programs,  the ability of the Company to establish  and  maintain  collaborative
arrangements  with others for drug  development,  progress with  preclinical and
clinical trials, the time and costs involved in obtaining regulatory  approvals,
the costs involved in preparing, filing, prosecuting,  maintaining and enforcing
patent claims,  competing technological and market developments,  changes in its
existing  research   relationships   and  effective  product   commercialization
activities and arrangements.

     The Company  believes that its current cash  resources and interest  income
thereon,  including  approximately $5.8 million in net cash and cash equivalents
received  by the  Company  from the  Private  Placement  Transaction,  should be
sufficient to fund its operating expenses and capital  requirements as currently
planned  through the first  quarter of 1998.  The Company  will seek  additional
funding through  collaborative  arrangements or through future public or private
equity or debt financing.  There can be no assurance that  additional  financing
will be available on acceptable  terms, or at all. In addition,  pursuant to the
Private  Placement  Transaction,  the Selling  Stockholders  are granted limited
rights to approve of the Company's efforts to obtain  convertible debt or equity
for a period of one hundred  eighty (180) days  following  the Closing  Date. If
additional  funds are raised by issuing equity  securities,  further dilution to
stockholders may result. If adequate funds are not available, the Company may be
required to delay,  reduce the scope of or eliminate one or more of its research
or  development   programs  or  to  obtain  funds  through   arrangements   with
collaborative  partners or others  that may  require  the Company to  relinquish
rights to certain of its technologies,  product  candidates or products that the
Company would otherwise seek to develop or commercialize itself.

Dependence on Potential Collaborative Partners

     The   Company's   strategy   for   the   development,   clinical   testing,
manufacturing,  marketing  and  commercialization  of  certain  of its  products
includes  entering  into  various   collaborations   with  corporate   partners,
licensors,  licensees  and  others.  To  date,  the  Company  has  entered  into
agreements  with  Bausch & Lomb to  manufacture  and market the  Company's  lead
product,  Lotemax(TM),  in the United States and throughout  Europe,  Canada and
selected  other  countries.  The  agreements  also cover the  co-development  of
Lotemax(TM)  line extension  products  currently being developed by the Company.
There can be no assurance  that the Company will be able to negotiate any future
collaborative  agreement  with Bausch & Lomb or other  companies  on  acceptable
terms,  or  that  any  present  or  future  collaborative   agreements  will  be
successful.  To the extent  that the  Company  chooses  not to or is not able to
establish such  arrangements,  the Company would  experience  increased  capital
requirements to undertake such activities at its own expense.  In addition,  the
Company may encounter  significant  delays in introducing its proposed  products
currently under development into certain markets or find that the development,

                                        2

<PAGE>


manufacture,  or sale of its  proposed  products  in such  markets is  adversely
affected by the absence of such collaborative agreements.

Technological Change and Competition

     The  pharmaceutical  industry  is  subject  to  rapid,   unpredictable  and
significant  technological  change.  Competition  from  universities,   research
institutions and other pharmaceutical,  chemical and biotechnology  companies is
intense.  Many  competitors  or potential  competitors  have  greater  financial
resources,   research  and  development  capabilities,   and  manufacturing  and
marketing experience than the Company. To this end, the Company has entered into
agreements  with Bausch & Lomb for the manufacture and marketing of Lotemax(TM).
There can be no assurance  that  developments  by the Company's  competitors  or
potential  competitors  will not render the  Company's  technology  or  proposed
applications of its technology obsolete.

Technologies Subject to Licenses

     As a licensee  of certain  research  technologies,  the Company has various
license  agreements with certain U.S.  federal agencies and the State of Israel,
certain  universities  and Dr.  Nicholas  Bodor,  a former  vice  president  and
director  of the  Company,  wherein  the  Company  has  acquired  exclusive  and
coexclusive rights to develop and commercialize  certain research  technologies.
The  agreements  generally  require  the  Company  to pay  royalties  on sale of
products  developed  from the licensed  technologies  and fees on revenues  from
sublicensees,  where applicable, and the Company is responsible for the costs of
filing and prosecuting patent applications.  In addition,  some of the Company's
license  agreements  require that the Company  commit  certain sums annually for
research  and  development  of the  licensed  products.  The  Company's  license
agreements with the University of Florida and with Dr. Bodor require the Company
to pay annual license  maintenance fees as well as make payments upon completion
of certain  milestones  occurring  in the  clinical  trials of certain  licensed
products.

     The exclusivity of license agreements generally expires fifteen years after
the  later  of  commercialization  or the  effectiveness  of the  patents.  Each
agreement  is  terminable  by either  party,  upon  notice,  if the other  party
defaults in its obligations.

Uncertainty of Protection of Patents and Proprietary Rights

     The  Company's  success  will depend in large part on its ability to obtain
patents,   maintain  trade  secrets  and  operate  without   infringing  on  the
proprietary  rights of  others,  both in the U.S.  and in other  countries.  The
patent positions of pharmaceutical companies can be highly uncertain and involve
complex   legal  and  factual   questions,   and   therefore   the  breadth  and
enforceability of claims allowed in pharmaceutical  patents cannot be predicted.
There  can be no  assurance  that any  issued  or  pending  patents  will not be
challenged,  invalidated or circumvented,  or that the rights granted thereunder
will provide proprietary protection or competitive advantages to the Company.


                                        3

<PAGE>


     The commercial success of the Company also will depend, in part, on Pharmos
not  infringing  patents  issued  to others  and not  breaching  the  technology
licenses upon which any Company products are based. It is uncertain  whether any
third-party patents will require the Company to alter its products or processes,
obtain licenses or cease certain activities.  In addition, if patents are issued
to others which contain  competitive or conflicting  claims, and such claims are
ultimately  determined  to be  valid,  the  Company  may be  required  to obtain
licenses to these patents or to develop or obtain alternative technology. If any
licenses are required,  there can be no assurance  that the Company will be able
to obtain any such  licenses on  commercially  favorable  terms,  if at all. The
Company's  breach of an  existing  license or failure to obtain a license to any
technology that it may require to commercialize its products may have a material
adverse  impact on the Company.  Litigation,  which could result in  substantial
costs to the Company,  may also be necessary to enforce any patents  licensed or
issued to the Company or to  determine  the scope and  validity  of  third-party
proprietary  rights.  If  competitors  of the  Company  prepare  and file patent
applications in the U.S. that claim technology also claimed by the Company,  the
Company may have to participate in interference proceedings declared by the U.S.
Patent and  Trademark  Office to determine  priority of  invention,  which could
result in  substantial  costs to the Company,  even if the  eventual  outcome is
favorable  to the  Company.  An adverse  outcome  could  subject  the Company to
significant liabilities to third parties, require disputed rights to be licensed
from third parties or require the Company to cease using such technology.

     The Company  also relies on secrecy to protect its  technology,  especially
where patent  protection is not believed to be appropriate or obtainable.  Thus,
Pharmos  protects  its  proprietary  technology  and  processes,   in  part,  by
confidentiality   agreements   with  its  employees,   consultants  and  certain
contractors.  There  can be no  assurance  that  these  agreements  will  not be
breached,  that the Company would have adequate remedies for any breach, or that
the Company's trade secrets will not otherwise  become known or be independently
discovered by competitors.

Legal Proceedings and Disputes

     There are  currently  no  material  legal  proceedings  pending  against or
involving the Company.

Extensive Government Regulation

     The Company's  products  require the approval of the FDA before they can be
marketed  in the U.S.  In  addition,  approvals  are also  required  from health
authorities  in most  foreign  countries  before the  Company's  products can be
marketed in such  countries.  Before an NDA, a type of submission used to obtain
FDA  approval  to market a new drug,  can be filed with the FDA, a product  must
undergo, among other things, extensive animal testing and human clinical trials,
which  can take up to seven  years to  complete.  Except  for  Lotemax(TM),  the
Company has not yet filed NDAs on its products. The time required for regulatory
approval of the Company's  products after  acceptance for filing an NDA can vary
and is usually  one to three years or more,  and the FDA may require  additional
animal studies and/or clinical trials before granting approval.  There can be no
assurance  that the FDA and foreign  regulatory  agencies will be satisfied with
the  information,  including that emanating from clinical  trials,  submitted to
them

                                        4

<PAGE>



in applications  (like NDAs) seeking  approval and will approve the marketing of
any of the Company's  potential  products,  or that problems will not arise that
could delay or prevent the commercialization of the Company's future products.

     There can be no  assurance  that any  potential  products  developed by the
Company  alone or in  conjunction  with  others  will be  proven  to be safe and
effective  in  clinical  trials and will meet all of the  applicable  regulatory
requirements   needed  to  receive  marketing   approval.   Data  obtained  from
preclinical   testing  and  clinical   trials  can  be  susceptible  to  varying
interpretations  which could delay,  limit or prevent regulatory  approvals.  In
addition,  delays or  disapprovals  may be  encountered  based  upon  additional
government regulation resulting from future legislation or administrative action
or changes in FDA policy made during the period of product  development  and FDA
regulatory review.  Similar delays may also be encountered in foreign countries.
There can be no assurance that even after such time and expenditures, regulatory
approval will be obtained for any potential  products  developed by the Company.
If regulatory approval of a product is granted, such approval will be limited to
those  therapeutic  uses for which the  product  has been  demonstrated  through
clinical studies and other means to be safe and effective. Furthermore, approval
may entail ongoing requirements for post-marketing  studies.  Even if regulatory
approval is obtained, a marketed product, its manufacturer and its manufacturing
facilities  are  subject to  continual  review  and  periodic  inspections.  The
regulatory  standards for manufacturing are currently being applied  stringently
by  the  FDA.   Discovery  of  previously   unknown  problems  with  a  product,
manufacturer  or facility  may result in FDA  restrictions  being placed on such
product or manufacturer  or facility,  including an order to withdraw a specific
product from the market, and may also result in court enforced sanctions against
the product, manufacturer or facility.

     The Company may establish  collaborative  relationships to conduct clinical
testing and seek  regulatory  approvals to market its products in major  markets
outside the U.S.  There can be no assurance  that the Company will be successful
in establishing such  relationships or that such approvals will be received in a
timely  manner,  if at all. To market its products  abroad,  the Company is also
subject to numerous and varying foreign regulatory requirements,  implemented by
foreign health  authorities,  governing the design and conduct of human clinical
trials, pricing and marketing. The approval procedure varies among countries and
can involve  additional  testing,  and the time required to obtain  approval may
differ from that required to obtain FDA approval. At present,  foreign marketing
authorizations are applied for at a national level, although within the European
Union ("EU") certain registration  procedures are available to companies wishing
to  market  a  product  in more  than one EU  member  country.  If a  regulatory
authority is satisfied  that adequate  evidence of safety,  quality and efficacy
has been  presented,  marketing  authorization  is almost  always  granted.  The
foreign  regulatory  approval  process includes all of the risks associated with
obtaining  FDA  approval  set forth  above.  Approval by the FDA does not ensure
approval by other countries.

Lack of Sales and Marketing Capability

     The Company has no  experience  in sales,  marketing  or  distribution.  To
market any of its products directly,  the Company must develop a marketing force
and sales  force  with  technical  expertise  and with  supporting  distribution
capability. Alternatively, the Company may obtain

                                        5

<PAGE>


     the assistance of a pharmaceutical company with an established distribution
system and sales force.  The Company has entered into  agreements  with Bausch &
Lomb to market Lotemax(TM). There can be no assurance, however, that the Company
will be able to establish sales and  distribution  capabilities or be successful
in gaining market acceptance for its products.

Lack of Manufacturing Capability

     The Company  currently  has limited  manufacturing  capacity to produce its
products  for  clinical  trials.  The  Company's  agreements  with Bausch & Lomb
address  the   manufacturing  of  Lotemax(TM).   The  proposed   products  under
development by the Company have never been  manufactured  on a commercial  scale
and there can be no assurances  that such products can be manufactured at a cost
or in  quantities  necessary  to make  them  commercially  viable.  Any delay in
availability  of products may result in delay in the  submission of products for
regulatory  approval or the market  introduction  and  subsequent  sales of such
products, which would have a material adverse effect on the Company.

Need to Attract and Retain Key Employees and Consultants

     The Company is highly dependent on the principal  members of its scientific
and  management  staff.  In  addition,  the Company  relies on  consultants  and
advisors to assist the  Company in  formulating  its  research  and  development
strategy. Retaining and attracting qualified personnel, consultants and advisors
will be  critical  to the  Company's  success.  In order to pursue  its  product
development and marketing plans, the Company will be required to hire additional
qualified scientific  personnel to perform research and development,  as well as
personnel   with   expertise  in  clinical   testing,   government   regulation,
manufacturing  and  marketing.  The  Company  faces  competition  for  qualified
individuals   from  numerous   pharmaceutical   and   biotechnology   companies,
universities and other research institutions. There can be no assurance that the
Company will be able to attract and retain such  individuals on acceptable terms
or at all.

     The Company's  clinical  development  is conducted  under  agreements  with
universities and medical  institutions.  The Company depends on the availability
of a principal investigator for each such program, and the Company cannot assure
that these  individuals  or their  research  staffs will be available to conduct
clinical development.  The Company's academic collaborators are not employees of
the Company.  As a result, the Company has limited control over their activities
and can expect  that only  limited  amounts of their time will be  dedicated  to
Company activities.  The Company's academic collaborators may have relationships
with other commercial entities, some of which compete with the Company.

Uncertainty of Health Care Reform Measures and Third-Party Reimbursement

     The  levels  of   revenues   and   profitability   of   biotechnology   and
pharmaceutical   companies  may  be  affected  by  the  continuing   efforts  of
governmental  and  third-party  payors to  contain or reduce the costs of health
care through various means. For example, in certain foreign markets,  pricing or
profitability of prescription  pharmaceuticals is subject to government control.
In the U.S.,  there have been, and the Company  expects that there will continue
to be, a number of federal  and state  proposals  to control  health care costs.
While the Company cannot predict

                                        6

<PAGE>


whether any such  legislative  or  regulatory  proposals  will be adopted or the
effect such proposals may have on its business, the uncertainty surrounding such
proposals could have a material adverse effect on the Company.  Furthermore, the
Company's  ability to  commercialize  its  potential  product  portfolio  may be
adversely  affected to the extent that such  proposals  have a material  adverse
effect on the business, financial condition and profitability of other companies
that  are  prospective  collaborators  for  certain  of the  Company's  proposed
products.

Dependence on Reimbursement

     Pharmos' ability to commercialize  its products  successfully may depend in
part on the  extent to which  reimbursement  for the cost of such  products  and
related  treatments  will be available  from  government  health  administration
authorities, private health insurers and other organizations. Third-party payors
are  increasingly  challenging  the  price of  medical  products  and  services.
Significant  uncertainty exists as to the reimbursement status of newly approved
health care products,  and there can be no assurance  that adequate  third-party
coverage will be available to enable Pharmos to maintain price levels sufficient
to realize an appropriate return on its investment in product development.

Risk of Product Liability; Availability of Insurance

     The design,  development and manufacture of the Company's  products involve
an inherent risk of product liability claims and associated  adverse  publicity.
Although the Company currently maintains general liability insurance,  there can
be no assurance  that the coverage  limits of the Company's  insurance  policies
will be adequate.  Similarly,  the Company  currently  maintains  clinical trial
liability  insurance,  but there can be no assurance  that the coverage limit of
the Company's insurance policies will be adequate.  The Company currently has no
product liability insurance, and there can be no assurance that the Company will
be able to obtain or maintain product liability insurance on acceptable terms or
with  adequate  coverage  against  potential  liabilities.   Such  insurance  is
expensive,  difficult  to  obtain  and may not be  available  in the  future  on
acceptable  terms or at all. A successful  claim brought  against the Company in
excess of the Company's  insurance coverage could have a material adverse effect
upon the Company and its financial condition.

Use of Hazardous  Materials;  Potential  Liability to Comply with  Environmental
Laws

     The  Company's  research and  development  involves the  controlled  use of
hazardous  materials.  Although the Company believes that its safety  procedures
for handling and  disposing of such  materials  comply in all material  respects
with the  standard  prescribed  by state and  federal  regulations,  the risk of
accidental  contamination  or injury from these  materials  cannot be completely
eliminated.  In the event of such an accident,  the Company could be held liable
for any damages that result,  and any such liability  could exceed the resources
of the  Company.  The  Company  may  incur  substantial  costs  to  comply  with
environmental regulations if the Company develops manufacturing capacity.


                                        7

<PAGE>


Market for the Company's  Securities;  Shares Eligible for Future Sale; Possible
Volatility of Share Prices

     The market price of the Company's Common Stock, like that of other emerging
pharmaceutical  companies,  has fluctuated  significantly in recent years and is
likely to  fluctuate  in the  future.  Announcements  by the  Company  or others
regarding  scientific  discoveries,   technological   innovations,   litigation,
products,  patents or  proprietary  rights,  the  progress of  clinical  trials,
government  regulation,  public  concern  as to the  safety  of  drugs  and  the
reliability of the Company's testing processes and general market conditions may
have a significant  impact on the market price of the Common Stock. The addition
of the shares being offered hereby and the shares  issuable upon exercise of the
Company's  currently   outstanding   warrants  and  options  to  the  number  of
publicly-traded  shares of the Company's  Common Stock may affect the volatility
of share prices of the Company's Common Stock.

Outstanding Stock Options and Warrants

     As of December 31, 1996 the Company had outstanding incentive stock options
to  purchase  an  aggregate  of  513,253  shares of Common  Stock at an  average
exercise price of $2.13 per share and non-qualified stock options to purchase an
aggregate of 432,182 at an average  exercise  price of $3.12 per share issued to
employees,  directors  and  consultants  pursuant  to  stock  option  plans  and
individual  agreements with management and directors of the Company and warrants
to purchase  3,138,789  shares of the Company's Common Stock at an average price
of $2.13 per share.

     The Company may issue additional capital stock,  warrants and/or options to
raise capital in the future.  The Company  regularly  examines  opportunities to
expand its  technology  base and product  line  through  means such as licenses,
joint  ventures and  acquisition  of assets or ongoing  businesses and may issue
securities in connection  with such  transactions.  However,  no  commitments to
enter  into or pursue  any such  transaction  have been made and there can be no
assurance that any such discussions  will result in any such  transaction  being
concluded.  In order to attract and retain key  personnel,  the Company may also
issue  additional  securities,  including stock options,  in connection with its
employee  benefit  plans.  During the terms of such  options and  warrants,  the
holders  thereof are given the  opportunity  to profit from a rise in the market
price of the Company's  Common Stock.  The exercise of such options and warrants
may have an adverse  effect on the market value of the  Company's  Common Stock.
Also, the existence of such options and warrants may adversely  affect the terms
on which the Company can obtain additional equity financing.

Convertible  Securities;  Potential  Dilution and Adverse  Impact on  Additional
Financing

     As of December 31, 1996, the Company had  outstanding  options and warrants
to purchase an  aggregate  of 4,084,224  shares of Common  Stock,  at a weighted
average  exercise  price of  $2.2347591  per share.  The Company is obligated to
issue up to 7,400,000  shares of Common Stock upon conversion of 1,400 shares of
the Series A Preferred  Stock and 6,000  shares of the Series B Preferred  Stock
(collectively,  the "Preferred Stock") outstanding as of April 4, 1997, based on
a conversion price of $1.00, which is derived from 80% of the closing


                                        8


<PAGE>


price of the  Common  Stock as of April 4, 1997.  The exact  number of shares of
Common  Stock  issuable  upon  conversion  cannot be  estimated  with  certainty
because,  generally, such issuances of Common Stock will vary inversely with the
market price of the Common Stock at the time of such conversion, and there is no
limit on the number of shares of Common Stock that may be  issuable.  The number
of shares of Common Stock  issuable upon  conversion  of the Preferred  Stock is
also subject to various  adjustments  to prevent  dilution  resulting from stock
splits,  stock dividends or similar  transactions.  Further, the Company may, at
its election,  choose to issue additional shares of Common Stock in lieu of cash
dividends due to the holders of the Preferred Stock.

     To the extent  shares of Common Stock are issued in lieu of cash  dividends
or due to  conversions  of the  Preferred  Stock,  substantial  dilution  of the
interests of the Company's stockholders is likely to result and the market price
of the Common Stock may be materially adversely affected.  Such dilution will be
greater if the future market price of the Common Stock  decreases.  For the life
of the Preferred  Stock,  the holders will have the opportunity to profit from a
rise in the price of the underlying  securities.  The existence of the Preferred
Stock is  likely  to  affect  materially  and  adversely  the terms on which the
Company can obtain additional financing,  and the holders of the Preferred Stock
can be  expected  to convert  shares of the  Preferred  Stock at a time when the
Company would otherwise, in all likelihood, be able to obtain additional capital
by an offering of its  unissued  capital  stock on terms more  favorable  to the
Company then those provided by the Preferred Stock.

     The Company has registered the Common Stock issuable upon conversion of the
Preferred Stock, certain of which are being offered pursuant to this Prospectus.
Shares of Common Stock issuable upon  conversion of the Series A Preferred Stock
are being offered  pursuant to a prospectus  included in Registration  Statement
No. 333-15165.  Following conversion, such registered shares of Common Stock can
be sold without any holding period or sales volume limitations.

Anti-Takeover Provisions

     The  Company is  subject  to  Sections  78.411-.444  of the Nevada  General
Corporation  Law ("Nevada  Law"),  an  anti-takeover  law,  which may discourage
certain types of transactions involving an actual or potential change in control
of the Company, including transactions in which the stockholders might otherwise
receive a premium for their  shares over the current  prices,  and may limit the
ability of the stockholders to approve a transaction that they may deem to be in
their best  interests.  In addition,  the Board of Directors  has the  authority
without  action by the  stockholders  to fix the rights and  preferences  of and
issue  shares of  Preferred  Stock,  which may have the  effect of  delaying  or
preventing a change in control of the Company.

Potential Future Acquisitions

     Due to the  current  uncertainties  of the  capital  markets  for  emerging
pharmaceutical  companies,  the Company  has had  preliminary  discussions  with
several  emerging  pharmaceutical  and  biotechnology  companies about potential
business and/or product consolidations, joint ventures, acquisitions, mergers or
other business combinations (collectively "acquisitions"). In


                                        9


<PAGE>


the event the Company  undertakes any such  acquisitions  it may use some of its
cash,  including  part of the cash  received  in  connection  with  the  Private
Placement Transaction, or may issue its stock in connection therewith.  Although
management  would attempt to structure such  acquisitions  in a manner that will
minimize dilution of the equity owned by current stockholders,  no assurance can
be given that  acquisitions  will not result in such dilution or that control of
the  Company  will  not be  changed  as a  result  of  such  acquisitions.  Such
acquisitions may be negotiated or may be sought on an unsolicited  basis and may
involve  speculative and risky  undertakings by the Company with increased risks
to its stockholders. Under Nevada law, acquisitions do not require shareholders'
approval except when accomplished by merger or  consolidation.  The Company does
not, in general,  intend to submit acquisitions to shareholder vote except where
required  by Nevada  law.  The  Company  has not  entered  into any  preliminary
undertaking with any third parties  involving any acquisitions or other business
combination transactions.

Special Considerations of Doing Business in Israel

     A significant  part of the operations of the Company is conducted in Israel
through its wholly-owned  subsidiary,  Pharmos Limited ("Pharmos Ltd."),  and is
directly  affected by economic,  political  and military  conditions  there.  In
addition, Pharmos Ltd. has received certain funding from the Office of the Chief
Scientist of the Israel  Ministry of Industry and Trade (the "Chief  Scientist")
relating  to its  proprietary  SubMicron  Emulsion  Technology  and has filed an
application  to receive  funding  with  respect to  Dexanabinol,  a new chemical
entity.  Such  funding  prohibits  the  transfer or license of know-how  and the
manufacture  of resulting  products  outside of Israel without the permission of
the  Chief  Scientist.  Although  it is the  Company's  belief  that  the  Chief
Scientist does not unreasonably withhold this permission if the request is based
upon commercially  justified  circumstances  and any royalty  obligations to the
Chief Scientist are  sufficiently  assured,  there can be no assurance that such
consent,  if requested,  would be granted upon terms satisfactory to the Company
or granted at all.

Absence of Dividends

     No dividends  have been paid on the Common  Stock to date,  and the Company
does not expect to pay cash dividends in the foreseeable future.

                                    DILUTION

     As of December  31, 1996,  the net  tangible  book value of the Company was
$1,150,479  or $0.04 per share.  Net tangible book value per share is determined
by dividing the net tangible book value  (tangible  assets less  liabilities) of
the Company by the number of shares of Common Stock outstanding at that date.

     If all of the 159,000  Warrants  exercisable  at an exercise price of $1.75
per share are  exercised  (each of the Warrants  purchasing  one share of Common
Stock),  there would be 30,868,169 shares of Common Stock outstanding with a net
tangible book value of $0.05 and the  purchasers of shares  through the exercise
of such Warrants at a price of $1.75 per share would suffer  immediate  dilution
of $1.70 per share.


                                       10


<PAGE>


                                 USE OF PROCEEDS

     The Company will receive no proceeds from the  10,000,000  shares of Common
Stock to be offered and resold by the Selling Stockholders.

     Assuming that all of the 159,000 Warrants whose underlying  Common Stock is
being offered  hereby are  exercised,  the gross  proceeds to be received by the
Company will be $278,250.  Such  proceeds  will be added to working  capital and
used for general  corporate  purposes.  The amount of proceeds to be received by
the Company, however, depends on the number of Warrants exercised.

     The Company  believes that its current cash  resources and interest  income
thereon,  including the funds obtained from the Private  Placement  Transaction,
should be sufficient to fund its operating expenses and capital  requirements as
currently  planned  through  the first  quarter  of 1998 (if  combined  with the
proceeds  from the  exercise of the  Warrants,  assuming all of the Warrants are
exercised  (as to which there can be no  assurances),  the  Company  should have
sufficient  resources to fund its operating expenses and capital requirements as
currently  planned through the first quarter of 1998). The amounts and timing of
expenditures  for each  purpose  will depend on the  progress  of the  Company's
research and development programs, technological advances,  determinations as to
commercial potential,  the terms of any collaborative  arrangements entered into
by the Company for development and licensing,  regulatory  approvals,  and other
factors, many of which are beyond the Company's control.

     Pending  such  uses,  the cash  received  in  connection  with the  Private
Placement Transaction and the net proceeds from the exercise of the Warrants (if
exercised)  will be invested in short-term,  interest-bearing  investment  grade
securities. Due to the current uncertainties of the capital markets for emerging
pharmaceutical  companies  the  Company  has had  preliminary  discussions  with
several  emerging  pharmaceutical  and  biotechnology  companies about potential
acquisitions.  Any such transaction  might involve the use of the Company's cash
resources as  consideration.  The Company has not entered  into any  preliminary
understanding  with any third  parties  involving  any  acquisitions  and is not
currently in any negotiations. See "Risk Factors -- Potential Acquisitions."

                            DESCRIPTION OF SECURITIES

Common Stock

     The Common Stock being offered hereby (i) by the Selling Stockholders, (ii)
by the Company upon the exercise of the Warrants,  and (iii) by any  "affiliate"
of the Company upon the resale of such Common Stock obtained from exercising the
Warrants is fully described in the Company's  Registration Statement on Form 8-A
dated January 30, 1984, filed pursuant to Section 12 of the Securities  Exchange
Act of 1934, as amended (the  "Exchange  Act").  See  "Incorporation  of Certain
Documents by Reference".

     The Company's  Restated Articles of Incorporation  currently  authorize the
issuance of up to 50,000,000  shares of Common Stock. As of April 4, 1997, there
are currently 31,166,115

                                       11


<PAGE>


shares  outstanding,  or 36,744,602  shares taking into account  exercise of all
outstanding  stock options (and stock options which the Company is contractually
obligated to issue) and warrants (including the Warrants).

Series A Preferred Stock

     The Company's  Restated Articles of Incorporation  currently  authorize the
issuance of up to  1,250,000  shares of  Preferred  Stock.  As of April 4, 1997,
1,400 shares,  designated as Series A Preferred  Stock, are currently issued and
outstanding and held by 3 stockholders.  The Series A Preferred Stock was issued
in connection with a private placement  completed on September 30, 1996. Holders
of Series A Preferred  Stock have the right to convert  their shares as follows:
up to 25% of their initial investment after 80 days from September 30, 1996 (the
"Series A Preferred  Stock  Closing  Date"),  up to a cumulative of 75% of their
initial  investment  after 180 days from the Series A  Preferred  Stock  Closing
Date, and up to a cumulative of 100% of their initial  investment after 360 days
from the Series A Preferred  Stock  Closing  Date,  at 80% to 83% of  prevailing
market prices at time of conversion.

     Of the authorized  Preferred  Stock,  6,000 shares,  designated as Series B
Preferred   Stock,   are  currently   issued  and  outstanding  and  held  by  4
stockholders.  The Series B Preferred  Stock was issued in  connection  with the
Private  Placement  Transaction.  Holders of Series B  Preferred  Stock have the
right to convert their shares as follows:  up to 40% of their initial investment
after 90 days from March 31, 1997 (the "Series B Preferred Stock Closing Date"),
up to a cumulative  of 80% of their initial  investment  after 180 days from the
Series B Preferred  Stock Closing Date,  and up to a cumulative of 100% of their
initial  investment  after 270 days from the Series B  Preferred  Stock  Closing
Date, at prevailing market prices at time of sale.

Warrants

     The  159,000  Warrants  exercisable  at an  exercise  price  of  $1.75  are
exercisable  commencing  March 31, 1998 and expire on March 31, 2001. All of the
Warrants contain  anti-dilution  provisions providing for an adjustment to their
respective  exercise  prices in the event that the Company effects a stock split
or stock  dividend.  In addition,  the number and kind of shares of Common Stock
underlying  the Warrants are subject to  adjustments in the event of any capital
reorganization,  or  reclassification  of the capital  stock of the Company,  or
consolidation or merger of the Company with another corporation or entity (other
than a  subsidiary  of the  Company  in which the  Company is the  surviving  or
continuing corporation and no change occurs in the Company's Common Stock).

Other Securities--Preferred Stock

     The Company's  Restated Articles of Incorporation  currently  authorize the
issuance of up to 1,250,000  shares of Preferred Stock, of which 1,400 shares of
Series  A  Preferred  Stock,  issued  in  connection  with a  private  placement
completed in September 1996 and 6,000 shares of Series B Preferred  Stock issued
in connection with the Private Placement  Transaction,  are currently issued and
outstanding as of April 4, 1997, and empower the Board of Directors, without the
necessity of further action or authorization by the  stockholders,  to authorize
the


                                       12


<PAGE>


issuance of  Preferred  Stock from time to time in one or more series and to fix
the relative  rights,  preferences  and  limitations  of each such  series.  The
issuance of Preferred Stock could  adversely  affect the voting power of holders
of Common Stock and the  likelihood  that such  holders  will  receive  dividend
payments and payments  upon  liquidation  and could have the effect of delaying,
deferring or  preventing a change in control of the Company.  The Company has no
present plan to issue any additional shares of Preferred Stock.

Other Securities--Options and Warrants

     As of  December  31,  1996,  the Company had  outstanding  incentive  stock
options to purchase an aggregate of 513,253 shares of Common Stock at an average
exercise price of $2.13 per share and non-qualified stock options to purchase an
aggregate of 432,182 at an average  exercise  price of $3.12 per share issued to
employees,  directors  and  consultants  pursuant  to  stock  option  plans  and
individual  agreements with management and directors of the Company and warrants
(excluding the Warrants) to purchase  3,138,789  shares of the Company's  Common
Stock at an average price of $2.13 per share,  consisting of:  240,744  warrants
which can be  exercised  until  March 1998 each to  purchase  a single  share of
Common Stock for $2.25; 268,917 warrants which can be exercised until March 1998
each to  purchase a single  share of Common  Stock for $2.82;  333,335  warrants
which can be  exercised  until  March 1998 each to  purchase  a single  share of
Common Stock for $1.65;  406,880  warrants  which can be exercised  until August
1998 each to purchase a single share of Common Stock for $2.98;  63,913 warrants
which can be exercised  until  September 1999 each to purchase a single share of
Common Stock for $2.30;  200,000  warrants which can be exercised  until October
1999 each to purchase a single share of Common Stock for $0.84; 500,000 warrants
which can be  exercised  until  April 2005 each to  purchase  a single  share of
Common Stock for $2.75;  10,000 Warrants which can be exercised until April 2005
each to purchase a single share of Common Stock for $0.78; 15,000 warrants which
can be  exercised  until  April 2000 each to  purchase a single  share of Common
Stock for $.75;  25,000 Warrants which can be exercised until April 2000 each to
purchase a single share of Common Stock for $1.00;  25,000 warrants which can be
exercised  until April 2000 each to purchase a single  share of Common Stock for
$1.50;  900,000 warrants which can be exercised until September 14, 2000 each to
purchase a single share of Common Stock for $1.80;  10,000 warrants which can be
exercised until October 2001 each to purchase a single share of Common Stock for
$1.88;  15,000 warrants which can be exercised until March 2002 each to purchase
a single share of Common Stock for $2.31; 50,000 warrants which can be exercised
from  September  1997 until  September  2000 each to purchase a single  share of
Common Stock for $1.75;  65,000  warrants  which can be exercised from September
1997 until  September  2007 each to purchase a single  share of Common Stock for
$1.34;  and 10,000  warrants  which can be exercised  from  November  1997 until
November 2002 each to purchase a single share of Common Stock for $1.39.

Nevada Anti-Takeover Laws

     The Company is subject to the provisions of Sections  78.411 through 78.444
of  the  Nevada  Law,  an  anti-takeover   statute  (the  "Business  Combination
Statute").   In  general,   the  Business   Combination   Statute   prohibits  a
publicly-held  Nevada  corporation  from  engaging  in a  "combination"  with an
"interested stockholder" for a period of three years after the date of the


                                       13


<PAGE>


transaction  in which the person became an interested  stockholder,  unless such
combination is approved in a prescribed  manner or satisfies  certain fair value
requirements.   For  the   purposes  of  the   Business   Combination   Statute,
"combination"  includes a merger, an asset sale, the issuance or transfer by the
corporation of its shares in one transaction or a series of transactions, having
an aggregate  fair market  value equal to five percent or more of the  aggregate
market  value  of  the  corporation's  outstanding  shares,  to  the  interested
stockholder or to an associate of the interested stockholder,  and certain other
types  of  transactions   resulting  in  a  financial   benefit  the  interested
stockholder.  An  "interested  stockholder"  is a person  who is the  beneficial
owner,  directly  or  indirectly,  of ten  percent or more of the  corporation's
voting stock or an affiliate  or associate of the  corporation  that at any time
within  the three  years  immediately  preceding  the date in  question  was the
beneficial  owner,  directly  or  indirectly,  of ten  percent  or  more  of the
corporation's voting stock.

     By an amendment to its  By-laws,  the Company has exempted  itself from the
provisions  of  Sections  78.378  through  78.3793 of the Nevada Law, a "control
share"  statute which  otherwise  prohibits an acquiring  person,  under certain
circumstances,  from voting certain shares of a target corporation's stock after
such  acquiring  person's  percentage of ownership of such  corporation's  stock
crosses  certain  thresholds,  unless  the  target  corporation's  disinterested
stockholders approve the granting of voting rights to such shares.

Transfer Agent and Registrar

     The transfer agent and registrar for the Company's Common Stock is American
Stock Transfer and Trust Company, New York, New York.

                              PLAN OF DISTRIBUTION

     The Shares offered hereby by the Selling Stockholders are 10,000,000 shares
of Common Stock issuable upon conversion of 6,000 shares  ($6,000,000  principal
amount) Series B Preferred Stock issued to the holders thereof by the Company in
connection with the Private Placement  Transaction.  This prospectus also covers
the  issuance  by the Company of up to 159,000  shares of Common  Stock upon the
exercise  of the  Warrants,  which were  issued in  connection  with the Private
Placement Transaction.

     The sale of all or a portion  of the  Shares  and  Warrant  Shares  offered
hereby by the  Selling  Stockholders  may be  effected  from time to time on the
over-the-counter  market  at  prevailing  prices at the time of such  sales,  at
prices  related to such  prevailing  prices or at negotiated  prices,  or by any
other means  permitted under the Securities  Act. The Selling  Stockholders  may
effect such transactions by selling to or though one or more broker-dealers, and
such  broker-dealers  may  receive  compensation  in the  form  of  underwriting
discounts, concessions or commissions from the Selling Stockholders. The Selling
Stockholders  and any  broker-dealers  that  participate in the distribution may
under certain circumstances be deemed to be "underwriters" within the meaning of
the Securities Act, and any commissions  received by such broker-dealers and any
profits  realized  on  the  resale  of  shares  by  them  may  be  deemed  to be
underwriting discounts and commissions under the Securities Act. The Company and
the


                                       14


<PAGE>


Selling Stockholders may agree to indemnify such broker-dealers  against certain
liabilities,  including,  without  limitation,  certain  liabilities  under  the
Securities  Act, or, if such  indemnity is  unavailable,  to  contribute  toward
amounts required to be paid in respect of such liabilities.

     To the extent required under the Securities Act, a supplemental  prospectus
will be  filed,  disclosing  (a) the  name of any such  broker-dealers,  (b) the
number of shares  involved,  (c) the price at which such  shares are to be sold,
(d)  the  commissions   paid  or  discounts  or  concessions   allowed  to  such
broker-dealers,  where applicable,  (e) that such broker-dealers did not conduct
any investigation to verify the information set out or incorporated by reference
in this  prospectus,  as  supplemented,  and (f)  other  facts  material  to the
transaction.

     There is no assurance that any of the Selling Stockholders will sell any or
all of the shares of Common Stock hereby.

     The  Company  has agreed to pay  certain  costs and  expenses  incurred  in
connection  with the  registration of the shares of Common Stock offered hereby,
except  that the  Selling  Stockholders  shall be  responsible  for all  selling
commissions, transfer taxes and related charges in connection with the offer and
sale of such shares.

     The Company  has agreed to keep the  Registration  Statement  of which this
Prospectus  forms a part  continuously  effective  until the earlier of the date
that all of such  Shares  have  been sold or three  years  from the date of this
Prospectus.

                            SELLING SECURITY HOLDERS

         The table below sets forth the name of each  Selling  Stockholder;  the
total amount of (i) shares of Common Stock  beneficially  owned by such security
holder as of April 4, 1997;  (ii) Warrant  Shares  issuable upon the exercise of
the Warrants  beneficially  owned by such security  holder;  (iii) the aggregate
amount of Common Stock and/or  Warrant  Shares which may be offered for sale for
the  account of such  security  holder in his/her  discretion  from time to time
pursuant to this Prospectus;  and (iv) the amount and percentage of Common Stock
which would be  beneficially  owned by such  security  holder  after sale of all
securities offered by the Selling  Stockholder  pursuant to this Prospectus,  if
they are  offered  and sold,  and  assuming  that any other  shares held by such
security  holders are not sold.  The  information  included  below is based upon
information  provided  by  the  Selling   Stockholders.   None  of  the  Selling
Stockholders  referred  to herein has held any  position  or office,  or had any
material relationship, with the Company or any of its predecessors or affiliates
within the last three  years,  except as noted  below,  and none of the  Selling
Stockholders  will own 1% or more of the outstanding  stock of the Company after
completion of the offering, except as noted below.

     For the  purposes  of  calculating  the  number of  shares of Common  Stock
beneficially owned by the Selling  Stockholders,  the number of shares of Common
Stock  calculated to be issuable in connection with the conversion of the Series
A  Preferred  Stock and the Series B  Preferred  Stock is based on a  conversion
price of $1.00,  which is derived  from 80% of the  closing  price of the Common
Stock as of April 4,  1997.  The  calculation  of the total  number of shares of
Common Stock to be offered hereby,  however,  is based on a hypothetical  market
price of the  Common  Stock at the time of such  conversion  of $0.72  per share
(approximate  conversion price of $0.60),  which price is below the market price
of the Common Stock as of April 4, 1997

                                       15

<PAGE>



(which was  $1.25).  The use of such  hypothetical  price is not  intended,  and
should in no way be  construed,  to  constitute  a  prediction  as to the future
market price of the Common Stock.

     Because  the  initial  issuance  by the  Company of the  Warrant  Shares to
non-affiliated  holders is covered by the  Registration  Statement of which this
Prospectus  forms a part and the resale thereof by such  non-affiliated  holders
need not be registered  under the Securities  Act, the table below does not list
the warrants held by the non-affiliated Selling Stockholders.

<TABLE>
<CAPTION>
===================================================================================================================================
                                  Shares of           Amount of           Shares of
                                  Common Stock        Warrant Shares      Common Stock
             Names                Beneficially        Issuable upon       and/or Warrant       Shares and Percentage of
(and position or office held in   Owned Prior         Exercise of         Shares               Shares Owned After
the Company)                      to Offering(1)      Warrants Held       Offered(2)           Completion of Offering
                                                                                               ====================================
                                                                                               Shares            Percentage(3)
===================================================================================================================================
<S>                                    <C>                       <C>               <C>              <C>                      <C>
Elliott Associates, L.P.               2,400,000(4)              63,600            4,000,000                0                   0
- -----------------------------------------------------------------------------------------------------------------------------------
Paresco, Inc.                          2,740,000(5)              42,400            2,666,667        1,140,000                3.5%
- -----------------------------------------------------------------------------------------------------------------------------------
Libertyview Fund, LLC                    155,009(6)               2,650              166,667           55,009                   *
- -----------------------------------------------------------------------------------------------------------------------------------
Libertyview Plus Fund                    505,000(7)               7,950              500,000          205,000                   *
- -----------------------------------------------------------------------------------------------------------------------------------
Westgate International,                1,600,000(8)              42,400            2,666,667                0                   0
L.P.
===================================================================================================================================
</TABLE>
- --------------------

*    Indicates ownership of less than 1%

(1)  Does  not  include   warrants/and   or  options  which  are  not  currently
     exercisable, including the Warrants.

(2)  Does not  include the Warrant  Shares  because the initial  issuance by the
     Company of the Warrant Shares to  non-affiliated  holders is covered by the
     Registration Statement of which this Prospectus forms a part and the resale
     thereof by such  non-affiliated  holders need not be  registered  under the
     Securities Act.

(3)  Based on 31,166,115 shares of Common Stock outstanding as of April 4, 1997,
     plus each  individual's  shares of Common Stock issuable upon conversion of
     Series A Preferred  Stock,  and/or  currently  exercisable  warrants and/or
     options.

(4)  Based on 2,400  shares  of Series B  Preferred  Stock  held by the  Selling
     Stockholder as of June 16, 1997.

(5)  Based on 1,140  shares of  Series A  Preferred  Stock  and 1,600  shares of
     Series B  Preferred  Stock held by the Selling  Stockholder  as of April 4,
     1997.

(6)  Based on 9 shares of Common  Stock,  55 shares of Series A Preferred  Stock
     and 100 shares of Series B Preferred Stock held by the Selling  Stockholder
     as of April 4, 1997.

(7)  Based on 205 shares of Series A Preferred  Stock and 300 shares of Series B
     Preferred Stock held by the Selling Stockholder as of April 4, 1997.

(8)  Based on 1,600  shares  of Series B  Preferred  Stock  held by the  Selling
     Stockholder as of June 16, 1997.

                                       16

<PAGE>

                               RECENT DEVELOPMENTS

     None.


                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

     The  following  documents  filed by the  Company  with the  Commission  are
incorporated herein by reference:

     (a) The  Company's  Annual  Report on Form 10-K,  for the fiscal year ended
December 31, 1996, filed pursuant to Section 13 of the Exchange Act.

     (b)  The  description  of the  Common  Stock  contained  in  the  Company's
Registration  Statement on Form 8-A dated  January 30, 1984,  filed  pursuant to
Section 12 of the Exchange Act.

     In  addition,  all reports and other  documents  to be filed by the Company
pursuant to Sections  13(a),  13(c),  14 and 15(d) of the Exchange Act, prior to
the filing of a  post-effective  amendment  which  indicates that all securities
offered hereby have been sold or which deregisters all securities offered hereby
then remaining  unsold,  as well as all such reports filed after the date hereof
and  prior  to  the  termination  of  this  offering,  shall  be  deemed  to  be
incorporated  by  reference  herein and shall be deemed to be a part hereof from
the date of the filing of each such report or document.

                     COMMISSION'S POLICY ON INDEMNIFICATION
                         FOR SECURITIES ACT LIABILITIES

     Article 12 of the Company's Restated Articles of Incorporation  directs the
Company to provide in its bylaws for provisions  relating to the indemnification
of directors  and officers to the full extent  permitted by law,  including  the
federal  securities  law.  Section  78.751 of the Nevada  Revised  Statutes,  as
amended,  authorizes  the Company to  indemnify  any  director or officer  under
certain  prescribed  circumstances  and subject to certain  limitations  against
certain costs and expenses,  including  attorneys'  fees actually and reasonably
incurred in  connection  with any action,  suit or  proceeding,  whether  civil,
criminal,  administrative or  investigative,  to which such person is a party by
reason of being a director  or officer of the Company if it is  determined  that
such person  acted in  accordance  with the  applicable  standard of conduct set
forth in such statutory  provisions.  The Company may also purchase and maintain
insurance  for the benefit of any director or officer which may cover claims for
which the Company could not indemnify such person.

     Insofar as  indemnification  for  liabilities  arising under the Act may be
permitted to directors,  officers, and controlling persons of the Company, or to
underwriters (or controlling  persons thereof) of which an officer,  partner, or
controlling  person  thereof is one of the  foregoing  pursuant to the foregoing
provisions or otherwise, the Company has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy
as expressed in the Act and is,  therefore,  unenforceable.  In the event that a
claim for


                                       17


<PAGE>


indemnification  against such liabilities (other than the payment by the Company
of expenses incurred or paid by any such persons,  in the successful  defense of
any action,  suit or  proceeding)  is asserted by any such persons in connection
with the securities being registered, the Company will, unless in the opinion of
its counsel the matter has been settled by  controlling  precedent,  submit to a
court of appropriate  jurisdiction the question of whether such  indemnification
by it is against  public  policy as expressed in the Act and will be governed by
the final adjudication of such issue.

                                 LEGAL OPINIONS

     Legal matters in connection  with the securities  being offered hereby will
be passed upon for the  Company by  Eilenberg & Zivian,  666 Third  Avenue,  New
York, New York 10017.

                                     EXPERTS

     The financial  statements  incorporated  in this Prospectus by reference to
the Annual Report on Form 10-K for the year ended  December 31, 1996,  have been
so incorporated in reliance on the report of Price  Waterhouse LLP,  independent
accountants,  given on the  authority  of said firm as experts in  auditing  and
accounting.

                                       18

<PAGE>


                               PHARMOS CORPORATION
                               -------------------

                                  June 20, 1997

                                      INDEX
                                      -----

                                                                       Page No.


THE COMPANY ...........................................................    1

RISK FACTORS ..........................................................    1

DILUTION ..............................................................   10

USE OF PROCEEDS .......................................................   11

DESCRIPTION OF SECURITIES .............................................   11

PLAN OF DISTRIBUTION ..................................................   14

SELLING SECURITY HOLDERS ..............................................   15

RECENT DEVELOPMENTS ...................................................   17

INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE .......................   17

COMMISSION'S POLICY ON INDEMNIFICATION
FOR SECURITIES ACT LIABILITIES ........................................   17

LEGAL OPINIONS ........................................................   18

EXPERTS ...............................................................   18




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