PHARMOS CORP
PRE 14A, 1998-08-07
PHARMACEUTICAL PREPARATIONS
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                               PHARMOS CORPORATION
                         33 Wood Avenue South, Suite 466
                                Iselin, NJ 08830
                                 (732) 603-3526
              ----------------------------------------------------

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

              ----------------------------------------------------


     NOTICE IS HEREBY  GIVEN,  that the Annual  Meeting of the  Stockholders  of
Pharmos  Corporation  (the "Company") will be held in New York, New York at 5:00
p.m. on September 16, 1998 at The Waldorf-Astoria, 301 Park Avenue, New York, NY
10022, (i) for the election of Directors of the Company to hold office until the
next annual  meeting of the  stockholders  and until their  successors  are duly
elected and  qualified;  (ii) to approve the  issuance of certain  shares of the
Company's common stock, par value $.03 (the "Common Stock"),  upon conversion of
the Company's Series C Convertible Participating Preferred Stock; (iii) to amend
the Company's  1997 Incentive and  Non-Qualified  Stock Option Plan; and (iv) to
transact  such other  business  as may  properly  come before the meeting or any
adjournment or adjournments thereof.

     The Board of  Directors  has fixed the close of business on August 14, 1998
as the record date for the determination of stockholders  entitled to notice of,
and to vote at, the Annual Meeting.

     If you do not expect to be personally present at the meeting, but wish your
stock to be voted  for the  business  to be  transacted  thereat,  the  Board of
Directors  requests  that you fill in,  sign  and date the  enclosed  proxy  and
promptly return it by mail in the postage paid envelope provided.

                                         BY ORDER OF THE BOARD OF DIRECTORS


                                            Haim Aviv, Ph.D.
                                            Chairman of the Board

August 17, 1998


PLEASE COMPLETE,  SIGN AND DATE THE ENCLOSED PROXY AND PROMPTLY RETURN IT IN THE
ENVELOPE PROVIDED. NO POSTAGE IS NECESSARY IF MAILED IN THE UNITED STATES.


<PAGE>



                               PHARMOS CORPORATION
                         33 Wood Avenue South, Suite 466
                                Iselin, NJ 08830
                                 (732) 603-3526

                                 PROXY STATEMENT

                       FOR ANNUAL MEETING OF STOCKHOLDERS
                        To be held on September 16, 1998

                                  INTRODUCTION

     The Annual Meeting is called to elect members of the Board of Directors, to
approve the issuance of certain shares of Common Stock upon conversion of Series
C Convertible  Participating  Preferred  Stock and to amend the  Company's  1997
Incentive and  Non-Qualified  Stock Option Plan. The Meeting,  however,  will be
open for the  transaction  of such other business as may properly come before it
although,  as of the date of this proxy  statement,  management does not know of
any other  business  that will come  before  the  Annual  Meeting.  If any other
matters do come before the Annual  Meeting,  the persons  named in the  enclosed
form of proxy are expected to vote said proxy in accordance  with their judgment
on such matters.

     This proxy statement and the accompanying proxy card are first being mailed
to stockholders on or about August 17, 1998. A copy of the Annual Report for the
fiscal  year  ended  December  31,  1997,  which  includes   audited   financial
statements,  is included herewith for those  stockholders of record as of August
14, 1998, the record date for the Annual Meeting.

     The  solicitation  of proxies in the  accompanying  form is made by, and on
behalf of, the Board of Directors,  and no  compensation  will be paid therefor.
There  will be no  solicitation  of  proxies  other  than  by  mail or  personal
solicitation  by officers and  employees  of the Company.  The Company will make
arrangements   with  brokerage  houses  and  other   custodians,   nominees  and
fiduciaries  for the forwarding of proxy  material to the  beneficial  owners of
shares held of record by such persons,  and such persons will be reimbursed  for
reasonable  expenses  incurred by them in  connection  therewith.  A stockholder
executing the accompanying proxy has the power to revoke it at any time prior to
the exercise  thereof by filing with the  Secretary  of the Company:  (i) a duly
executed proxy bearing a later date; or (ii) a written  instrument  revoking the
proxy.

     With regard to the election of Directors,  votes may be cast in favor of or
withheld from each nominee. Abstention and "Broker Non-votes" (as defined below)
are  counted  for  purposes  of  determining  whether a quorum is present at the
Annual  Meeting,  but do not represent  votes cast with respect to any proposal.
"Broker  Non-votes" are shares held by a broker or nominee for which an executed
proxy is received by the Company,  but are not voted as to one or more proposals
because  instructions  have not been  received  from the  beneficial  owners  or
persons  entitled to vote and the broker or nominee does not have  discretionary
voting power.



<PAGE>



                                VOTING SECURITIES

     The Board of  Directors  has fixed the close of business on August 14, 1998
as the record date for the determination of stockholders  entitled to notice of,
and to vote at, the Annual Meeting.

     As of July 31, 1998, the outstanding capital stock of the Company consisted
of 37,270,949 shares of Common Stock. Each holder of Common Stock is entitled to
one vote  for each  share of  Common  Stock  held by him or her at the  close of
business on the record date.

     The  shares for which the  accompanying  proxy is  solicited  will be voted
providing  the proxy is executed  and returned by the  stockholder  prior to the
Annual Meeting.

     The  following  table sets forth  certain  information  with respect to the
beneficial  ownership of the  Company's  Common Stock as of July 31, 1998 by (i)
each person who was known by the Company to own beneficially more than 5% of any
class of the Company's Stock,  (ii) each of the Company's  Directors,  and (iii)
all current Directors and executive  officers of the Company as a group.  Except
as otherwise  noted,  each person  listed below has sole voting and  dispositive
power with respect to the shares listed next to such person's name.



                                           Amount
Name and Address of                     of Beneficial                Percentage
Beneficial Ownership                      Ownership                 of Total (1)
- - --------------------                      ---------                 ------------

Haim Aviv, Ph.D.(2)                      1,229,805                       3.3%
c/o Pharmos Ltd.
Kiryat Weitzman
Rehovot, Israel

Marvin P. Loeb(3)                          298,996                         *
Trimedyne, Inc.
2810 Barranca Road
Irvine, CA 92714

E. Andrews Grinstead III(4)                104,078                         *
Hybridon, Inc.
620 Memorial Drive
Cambridge, MA 02139

Stephen C. Knight, M.D.                      0                             *
Epix Medical Inc.
71 Rogers Street
Cambridge, MA 02142


                                       -3-

<PAGE>



                                           Amount
Name and Address of                     of Beneficial                Percentage
Beneficial Ownership                      Ownership                 of Total (1)
- - --------------------                      ---------                 ------------

David Schlachet(4)                          11,667                         *
Strauss Holdings Ltd.
16 Bazel Street
Petach-Tikva, Israel 49510

Fredric D. Price(5)                         31,750                         *
AMBI Inc.
771 Old Saw Mill River
Road
Tarrytown, NY 10591

Mony Ben Dor                                     0                         0
The Israel Corporation
4 Weizman St.
Tel-Aviv 61336, Israel

All Directors and                        1,805,079                       4.8%
Executive Officers
as a group
(10 persons)(6)

- - ----------

*    Indicates ownership of less than 1%.

(1)  Based  on  37,270,949  shares  of  Common  Stock  outstanding,   plus  each
     individual's  currently  exercisable  warrants or options.  Assumes that no
     other individual will exercise any warrants and/or options.

(2)  Includes 276,153 shares of Common Stock held in the name of Avitek Ltd., of
     which Dr. Aviv is the Chairman of the Board of Directors  and the principal
     stockholder,  and,  as such,  shares the right to vote and  dispose of such
     shares.  Also  includes  currently  exercisable  options  and  warrants  to
     purchase 317,876 shares of Common Stock.

(3)  Held jointly with his wife. Also includes currently exercisable options and
     warrants to purchase 48,340 shares of Common Stock. Does not include shares
     held by his adult children, his grandchildren or a trust for the benefit of
     his grandchildren.

(4)  Consists of currently  exercisable  options and warrants to purchase Common
     Stock.

(5)  Includes  currently  exercisable  options and  warrants to purchase  30,000
     shares of Common Stock.

(6)  Based on the number of shares of Common  Stock  outstanding,  plus  640,744
     currently  exercisable  warrants  and/or  options held by the Directors and
     executive officers.



                                       -4-

<PAGE>



                         ITEM 1 - ELECTION OF DIRECTORS

     Seven  Directors  are to be elected at the  Annual  Meeting to hold  office
until the next annual meeting of  stockholders  and until their  successors have
been duly  elected  and  qualified.  The  election  of  Directors  requires  the
affirmative  vote of a plurality of shares cast of Common Stock voting  together
present or  represented at a meeting at which a quorum  (one-third  (1/3) of the
outstanding  shares of Common Stock) is present or  represented.  Abstention and
Broker  Non-votes  are counted for purposes of  determining  whether a quorum is
present, but do not represent votes cast with respect to any proposal. It is the
intention of the persons  named in the  accompanying  proxy form to vote FOR the
election  of the seven  persons  named in the table  below as  Directors  of the
Company,  unless  authority to do so is withheld.  Proxies cannot be voted for a
greater number of persons than the nominees  named. In the event that any of the
below listed  nominees for Director  should become  unavailable for election for
any presently  unforeseen  reason,  the persons named in the accompanying  proxy
form have the right to use their discretion to vote for a substitute.

     The following  table sets forth the name, age and position of each Director
and executive officer:


Name                                Age      Position
- - ----                                ---      --------

Haim Aviv, Ph.D.                    57       Chairman, Chief Executive 
                                               Officer, Chief Scientist

Marvin P. Loeb                      71       Director

E. Andrews Grinstead III            53       Director

Stephen C. Knight, M.D.             38       Director

David Schlachet                     52       Director

Mony Ben Dor                        52       Director

Georges Anthony  Marcel,
M.D., Ph.D.                         57       Director (Nominee)

Gad Riesenfeld, Ph.D.               54       President and Chief 
                                               Operating Officer

Robert W. Cook                      43       Vice President Finance and 
                                               Chief Financial Officer

Anat Biegon, Ph.D.                  44       Vice President/Research 
                                               and Development

                                       -5-

<PAGE>



     Haim Aviv,  Ph.D.,  is Chairman of the Board of Directors,  Chief Executive
Officer,  and Chief  Scientist of the Company and  co-founded  in 1990,  Pharmos
Corporation,  a New York  corporation  ("Old  Pharmos"),  which  merged into the
Company on October 29, 1992 (the  "Merger").  Dr. Aviv also served as  Chairman,
Chief Executive  Officer and Chief Scientist of Old Pharmos prior to the Merger.
Dr. Aviv was the co-founder in 1980 of Bio-Technology  General Corp.  ("BTG"), a
publicly-traded company engaged in the development of products using recombinant
DNA, its General  Manager and Chief  Scientist from 1980 to 1985, and a Director
and Senior Scientific Consultant until August 1993. Prior to that time, Dr. Aviv
was a professor of molecular biology at the Weizmann  Institute of Science.  Dr.
Aviv is the principal  stockholder of Avitek Ltd., a stockholder of the Company.
Dr.  Aviv  is  also  an  officer  and/or  significant   stockholder  of  several
privately-held  Israeli  pharmaceutical and venture capital companies and is the
Chairman of the Israel National Committee for Biotechnology.

     E.  Andrews  Grinstead,  III, a Director  of the  Company  since  1991,  is
Chairman  and  Chief  Executive  Officer  of  Hybridon,  Inc.,  a  publicly-held
biotechnology  company.  Mr.  Grinstead  joined  Hybridon in 1991.  From 1987 to
October 1990, he was Managing Director and group head of the life sciences group
at Paine Webber, Inc. From 1986 to 1987, Mr. Grinstead was Managing Director and
group head of the life sciences  group at Drexel Burnham  Lambert.  From 1984 to
1986, he was a Vice President at Kidder, Peabody & Co., Inc., where he developed
the life sciences corporate finance specialty group. Prior to his seven years on
Wall Street,  Mr.  Grinstead  served in a variety of  operational  and executive
positions  with Eli  Lilly &  Company,  most  recently  as  general  manager  of
Venezuelan  Pharmaceutical,  Animal Health and Agricultural Chemical Operations.
Since 1991, Mr. Grinstead has served as a Director of EcoScience Corporation,  a
development-stage company engaged in the development of biopesticides, and since
1996, as a Director of Meridian Medical Technologies, Inc., a pharmaceutical and
medical device company.  Since 1994, Mr. Grinstead has served as a member of the
Board of  Trustees  for the Albert B.  Sabine  Vaccine  Foundation,  a 501(c)(3)
charitable  foundation  dedicated  to  disease  prevention.  Mr.  Grinstead  was
appointed to the President's Council of the National Academy of Sciences and the
Institute of Medicine in 1992.

     Marvin P. Loeb, a Director,  was Chairman of the Board of the Company (then
known as Pharmatec,  Inc.) from December 1982 through  October 1992. He has been
Chairman of Trimedyne,  Inc. (and its  subsidiaries),  a  publicly-held  company
engaged in the manufacture of lasers, optical fibers and laser delivery systems,
since April 1981;  a Director of Gynex  Pharmaceuticals,  Inc.,  from April 1986
until its merger with and into  Biotechnology  General  Corporation  in 1993,  a
publicly-held  company  engaged  in the  development  and  commercialization  of
pharmaceutical  products; a Director of Petrogen, Inc., a privately-held company
engaged in the  genetic  engineering  of  bacteria  for cleanup of oil waste and
toxic  waste,  from April 1987 to April 1992  (Chairman  from  November  1980 to
December 1982 and from July 1983 to April 1987); Chairman of Automedix Sciences,
Inc., an inactive, publicly-held company engaged in the

                                       -6-

<PAGE>



development of products for treating cancer and other  diseases,  from September
1980 to August 1995;  Chairman of Cardiomedics,  Inc., a privately-held  company
engaged in the manufacturing of heart assist devices, from May 1986; Chairman of
Xtramedics, Inc., a publicly-held company developing a feminine hygiene product,
from November  1986 to February 1994 and a Director of Xtramedics  from November
1986 until May 1994; Chairman of Ultramedics, Inc., an inactive,  privately-held
company developing blood treatment products,  since November 1988; and President
and Director of Marvin P. Loeb & Co.  since 1965,  and Master  Health  Services,
Inc. since 1972, both of which are family-held companies engaged in licensing of
inventions and financial consulting.

     Stephen C.  Knight,  M.D., a Director of the Company  since 1994,  is Chief
Financial Officer and Senior Vice President of Financial Business Development at
Epix Medical,  Inc. Prior to joining Epix Medical in July 1996, Dr. Knight was a
Senior  Consultant  at Arthur D. Little,  Inc.  While at Arthur D.  Little,  Dr.
Knight  specialized  in  mergers  and  acquisitions,   strategic  planning,  and
valuation in the  pharmaceutical  industry.  Dr.  Knight has  performed  medical
research at the National Institutes of Health, AT&T Bell Laboratories,  and Yale
and Columbia Universities.  Dr. Knight received an M.D. from the Yale University
School of Medicine  and a Master's  Degree from the Yale School of  Organization
and Management.

     David Schlachet, a Director of the Company since 1994, is Vice President of
the Strauss Group and C.E.O. of Strauss Holdings (Strauss Holdings  incorporates
the activities of the Group,  comprised of its core business, the food industry,
and other holdings in the area of commercial T.V.,  retail chains and investment
banking). In June 1997, Mr. Schlachet was elected Chairman of the Board of Elite
Industries  Ltd. when the Strauss Group  acquired  control of Elite,  one of the
largest food companies in Israel, with operations in Western and Eastern Europe.
Elite is a leader in the  Israeli  coffee,  chocolate,  confectionery  and salty
snack markets. Mr. Schlachet was Vice President of Finance and Administration at
the  Weizmann  Institute  of Science in Rehovot,  Israel,  from 1990 to December
1996. Mr.  Schlachet was  responsible  for the  Institute's  administration  and
financial  activities,   including  personnel,   budget  and  finance,  funding,
investments,  acquisitions  and  collaboration  with the industrial and business
communities.  From 1989 to 1990, Mr. Schlachet was President and Chief Executive
Officer of Yeda Research and  Development  Co.,  Ltd., a marketing and licensing
company at the  Weizmann  Institute of Science.  Mr.  Schlachet is a Director of
Taya Investment Company Ltd., an Israeli publicly-held investment company.

     Mony Ben Dor, a Director of the Company  since 1997,  is Vice  President of
The Israel Corporations,  Ltd. and Chairman of two publicly traded subsidiaries:
H.L.  Finance and Leasing and Albany Bonded  International  Trade.  He is also a
director of a number of subsidiary  companies of Israel Chemicals Ltd. From 1992
to 1997,  Mr.  Ben Dor was  Vice  President  of  Business  Development  for Clal
Industries  Ltd.  (a  subsidiary  of Clal  Israel),  which is one of the leading
investment  groups in Israel.  He was actively  involved in the  acquisition  of
companies  including  Jaffora Ltd. and a portfolio of  pharmaceutical  companies
including  Pharmaceutical  Resources  Inc.  and  Finetech  Ltd.  He  served as a
director representing Clal Industries in all of the

                                       -7-

<PAGE>



acquired  companies as well as other companies of Clal Industries.  Prior to his
position at Clal  Industries  Ltd., Mr. Ben Dor served as Business  Executive at
the Eisenberg Group of companies.

     Georges Anthony Marcel, M.D., Ph.D., a nominee for Director of the Company,
is  President  and  Chief  Executive   Officer  of  TMC   Development   S.A.,  a
biopharmaceutical  consulting firm based in Paris, France. Prior to founding TMC
Development in 1992, Dr. Marcel held a number of senior  executive  positions in
the pharmaceutical industry, including Chief Executive Officer of Amgen's French
subsidiary,  Vice President of Marketing for Rhone-Poulenc Sante and Director of
Development  for  Roussel-Uclaf.  Dr. Marcel  teaches  biotechnology  industrial
issues and European regulatory affairs at the Faculties of Pharmacy of Paris and
Lille. Dr. Marcel is also a member of the Gene Therapy Advisory Committee at the
French Medicines Agency.

     Gad  Riesenfeld,  Ph.D.,  was named  President  in February  1997 and Chief
Operating  Officer in March 1995 and served as  Executive  Vice  President  from
December  1994 to February  1997.  He had been the Vice  President  of Corporate
Development and General Manager of Florida Operations since October 1992 and was
employed by Pharmos Ltd. from March 1992 until the Merger. Prior thereto, he was
engaged  in  free-lance   consulting  relating  to  the   commercialization   of
intellectual property,  primarily in the pharmaceutical and medical fields. From
March  1990  through  May 1991 Dr.  Riesenfeld  was a  Director  and  Manager of
Kamapharm  Ltd., a private company  specializing in human blood products.  Prior
thereto,  from May 1986,  he was  Managing  Director of Galisar  Ltd., a private
company involved in extracorporeal blood therapy.

     Robert W. Cook was named  Vice  President  -- Finance  and Chief  Financial
Officer in January 1998. From May 1995 until joining the Company,  he was a vice
president in GE Capital's commercial finance subsidiary, based in New York. From
1978 until  1995,  Mr.  Cook held a variety of  corporate  finance  and  capital
markets  positions at The Chase  Manhattan Bank, both in the U.S. and in several
overseas  locations.  He was named a managing director of Chase in January 1986.
Mr. Cook holds a degree in international  finance from The American  University,
Washington, D.C.

     Anat Biegon, Ph.D., was named Vice President of Research and Development in
December  1994.  Dr.  Biegon  became head of Research  and  Development  for the
Company in 1994.  From 1992 to 1994, Dr. Biegon was a director in Pharmos Ltd.'s
Department of Pharmacology.  From 1991 to 1992, she was a Staff  Physiologist at
the  University  of  California  at  Berkeley's  Lawrence  Berkeley  Laboratory,
Division of Research Medicine and Radiation  Biophysics.  From 1990 to 1991, Dr.
Biegon was a Research Associate Professor in the Department of Psychiatry at New
York  University  Medical  Center.  From  1988 to  1990,  she  was an  Associate
Professor  in the  Department  of  Neurobiology  at the  Weizmann  Institute  of
Science.

                                       -8-

<PAGE>


                   BOARD OF DIRECTORS MEETINGS AND COMMITTEES

     During  the  1997  fiscal  year,  there  were 5  meetings  of the  Board of
Directors. A quorum of Directors was present,  either in person or by telephonic
hookup, for all of the meetings.  Actions were also taken during the year by the
unanimous written consent of the Directors.

     The members of the Audit Committee in 1997 were David Schlachet and Fredric
Price.  Actions  of the  Audit  Committee  were  taken  during  the  year by the
unanimous  written  consent  of the  Directors.  The  Audit  Committee  has been
delegated the  responsibility  of reviewing  with the  independent  auditors the
plans and results of the audit  engagement,  reviewing the  adequacy,  scope and
results of the internal accounting controls and procedures, reviewing the degree
of independence of the auditors,  reviewing the auditor's fees and  recommending
the engagement of the auditors to the full Board of Directors.

     In 1997, the Compensation  and Stock Option Committee  consisted of Messrs.
Loeb and Grinstead.  Actions of the Compensation and Stock Option Committee were
taken during the year by the unanimous  written  consent of the  Directors.  The
Compensation  and Stock  Option  Committee  has the full power and  authority to
interpret the provisions and supervise the administration of the Company's stock
option plans and to grant  options  outside of these plans and the  authority to
review all matters relating to personnel of the Company.

     The Board of Directors does not have a standing nominating committee.

Executive Compensation

     The  following  table  summarizes  the  total  compensation  of  the  Chief
Executive Officer of the Company for 1997 and the two previous years, as well as
all other executive officers of the Company who received  compensation in excess
of $100,000 for 1997.

Summary Compensation Table

<TABLE>
<CAPTION>
                               Annual Compensation                                 Long Term Compensation
                               -------------------                                 ----------------------

                                                                                                 Stock
Name/                                                                              Restricted Underlying
Principal Position               Year     Salary         Bonus         Other          Stock     Options
- - -------------                    ----      ----          ----          -----         -------   --------
<S>                             <C>     <C>           <C>           <C>                           <C>
Haim Aviv, Ph.D
Chairman, Chief                 1997    $227,471      $ 40,000      $ 16,119 (1)
Executive Officer, and          1996     236,453                      27,435 (1)
Chief Scientist                 1995     200,230                                                  324,376

Gad Riesenfeld, Ph.D
President and                   1997    $175,000                      44,948 (2)
Chief Operating Officer         1996     150,000                      43,798 (2)
                                1995     136,664                      34,481 (2)                   79,333
Alan M. Mark
Acting Chief                    1997                                $255,000 (3)
Financial Officer(4)            1996                                 150,000 (3)

Anat Biegon, Ph.D
Vice President of               1997    $ 81,873      $ 20,456      $ 27,860 (1)
Research and                    1996      85,516                      26,565 (1)
Development
</TABLE>
                                       -9-

<PAGE>


- - ----------

(1)  Consists of  contributions  to insurance  premiums,  car  allowance and car
     expenses.

(2)  Consists of housing allowance, contributions to insurance premiums, and car
     allowance.

(3)  Consists of non-employee compensation.

(4)  Acting Chief Financial Officer from July 1996 through July 1997. On January
     1, 1998, Mr. Robert W. Cook was appointed Vice President  Finance and Chief
     Financial Officer of the Company.

     The  following  tables  set forth  information  with  respect  to the named
executive  officers  concerning  the grant,  repricing  and  exercise of options
during the last fiscal year and  unexercised  options  held as of the end of the
fiscal year.

Option Grants for the Year
Ended December 31, 1997:

   None.(1)(2)(3)

- - ------------

(1)  In 1997, the Company issued  warrants to purchase an aggregate of 1,030,000
     shares  of  common  stock to  certain  employees  of the  Company.  Of such
     warrants,  955,000 were granted at an exercise price of $1.59 per share and
     75,000 were granted at an exercise  price of $1.66 per share,  250,000 were
     issued to Dr. Aviv, 175,000 were issued to Dr. Riesenfeld, and 125,000 were
     issued to Dr. Biegon. Such warrants become exercisable in increments of 25%
     each, on their respective  anniversary dates, in the years 1998, 1999, 2000
     and 2001. All of such warrants expire in the year 2007.

(2)  In 1997, the Company issued an aggregate of 201,052  warrants to Alan Mark.
     Of such  warrants  15,000  were  issued at an  exercise  price of $1.59 per
     share,  15,000  were  issued  at an  exercise  price of $1.22 per share and
     171,052  were issued at an exercise  price of $1.38 per share.  The 171,052
     warrants were issued as a finders fee for a private  placement  transaction
     that was completed in March 1997.

(3)  On January 9, 1998,  the Company issued options to purchase an aggregate of
     100,000  shares of common stock at an exercise  price of $2.00 to Robert W.
     Cook, the Company's new Chief Financial  Officer.  Of such options,  25,000
     vested immediately, and the remainder will become exercisable in increments
     of 25,000  on  January  1,  1999,  January  1, 2000 and  January  1,  2001,
     respectively.



                                      -10-

<PAGE>

Aggregated Option Exercises
for the Year Ended December 31, 1997
and Option Values as of December 31, 1997:

<TABLE>
<CAPTION>
                                                                                      Value of Unexercised
                          Number of                     Number of Unexercised       In-the-Money Options at
                           Shares                   Options at December 31, 1997       December 31, 1997
                         Acquired on    Value       ----------------------------   --------------------------
Name                      Exercise    Realized       Exercisable  Unexercisable    Exercisable  Unexercisable
- - ----                       -------    --------       -----------  -------------    -----------  -------------
<S>                           <C>         <C>         <C>             <C>           <C>           <C>
Haim Aviv,                                                                         
Ph.D                          0           0           255,376         69,000        $72,000       $48,000
                                                                                   
                                                                                   
Gad                                                                                
Riesenfeld,                   0           0            57,466         21,867        $48,000       $32,000
Ph.D                                                                               
                                                                                   
                                                                                   
Anat Biegon,                  0           0            34,426         16,107        $36,000       $24,000
Ph.D                                                                             
</TABLE>


                                      -11-

<PAGE>



                        REPORT OF COMPENSATION COMMITTEE

     The following  report of the  Compensation  Committee is provided solely to
the  shareholders  of the Company  pursuant to the  requirements of Schedule 14A
promulgated  under the Securities  Exchange Act of 1934, and shall not be deemed
to be "filed" with the  Securities  and Exchange  Commission  for the purpose of
establishing  statutory  liability.  This  Report  shall  not  be  deemed  to be
incorporated by reference in any document  previously or subsequently filed with
the Securities and Exchange Commission that incorporates by reference all or any
portion of this Proxy Statement.

     The  Compensation  and Stock  Option  Committee  of the Board of  Directors
establishes the general  compensation  policies of the Company,  establishes the
compensation plans and specific compensation levels for executive officers,  and
administers  the 1997 Incentive and  Non-Qualified  Stock Option Plan as well as
the  Company's  other Stock  Option  Plans.  The  Compensation  and Stock Option
Committee is composed of two  independent,  non-employee  Directors  who have no
interlocking  relationships as defined by the Securities and Exchange Commission
other  than as  described  below (see  "Compensation  Committee  Interlocks  and
Insider Participation").

     The  Compensation  and  Stock  Option  Committee,   being  responsible  for
overseeing and approving executive  compensation and grants of stock options, is
in  a  position  to   appropriately   balance  the  current  cash   compensation
considerations   with  the   longer-range   incentive-oriented   growth  outlook
associated with stock options. The main objectives of the Company's compensation
structure  include rewarding  individuals for their respective  contributions to
the  Company's  performance,  providing  executive  officers with a stake in the
long-term success of the Company and providing  compensation  policies that will
attract and retain qualified executive personnel.

     The  Compensation  and  Stock  Option  Committee  believes  that the  chief
executive  officer's (CEO) compensation  should be heavily influenced by Company
performance.  Although  Dr.  Aviv's  existing  agreements  with the Company (see
"Employment/Consulting  Contracts/Directors'  Compensation")  provide for a base
level of salary  and  consulting  compensation,  the  Committee  determines  the
appropriate  level of  bonuses  and  increases,  if any,  based in large part on
Company  performance.  The  Committee  also  considers  the  salaries of CEOs of
comparably-sized companies and their performance.

     Stock  options are granted to the CEO,  as to other  executives,  primarily
based on the executive's ability to influence the Company's long-term growth.

     The  Compensation  and Stock Option  Committee has adopted similar policies
with respect to  compensation  of other  officers of the Company.  The Committee
establishes  base  salaries  that are within the range of  salaries  for persons
holding similarly  responsible  positions at other companies.  In addition,  the
Committee considers factors such as relative Company

                                      -12-

<PAGE>



performance,   the  individual's   past  performance  and  future  potential  in
establishing the base salaries of executive officers.

     As with the CEO,  the number of options  granted to the other  officers  is
determined by the subjective  evaluation of the executive's ability to influence
the  Company's  long-term  growth.  All  options are granted at no less than the
current market price.  Since the value of an option bears a direct  relationship
to the  Company's  stock  price,  it is an effective  incentive  for managers to
create value for stockholders. The Committee therefore views stock options as an
important component of its long-term, performance-based compensation philosophy.



                                    Members of the Compensation and
                                      Stock Option Committee

                                    Marvin P. Loeb
                                    E. Andrews Grinstead III

                                      -13-

<PAGE>



             EMPLOYMENT/CONSULTING CONTRACTS/DIRECTORS' COMPENSATION


     Haim Aviv,  Ph.D. In addition to serving as Chairman of the Board and Chief
Executive  Officer of the  Company,  Dr. Aviv has provided  consulting  services
under a consulting  agreement with an initial three-year term ended May 3, 1993.
The term automatically  renews for additional one-year periods unless either the
Company  or Dr.  Aviv  terminates  the  agreement  at least  90 days  prior to a
scheduled expiration date. The agreement has been renewed on an annual basis and
presently expires on May 3, 1999. Dr. Aviv is entitled to severance pay equal to
25% of his salary in the event of  termination  or  non-renewal  without  cause.
Under the agreement,  Dr. Aviv is required to render certain consulting services
to the Company and in consideration  therefore,  Dr. Aviv is entitled to receive
$170,000 per year, subject to yearly increases and review.

     The  Company's  subsidiary,  Pharmos  Ltd.,  employs  Dr. Aviv as its Chief
Executive Officer under an employment  agreement with Dr. Aviv pursuant to which
Dr. Aviv receives $50,000 per year,  subject to yearly increases and review. Dr.
Aviv is required to devote at least 50% of his  business  time and  attention to
the business of Pharmos, Ltd. and to serve on its Board of Directors.

     Gad Riesenfeld,  Ph.D. In October 1992, Old Pharmos entered into a one-year
employment agreement with Dr. Riesenfeld,  which is automatically  renewable for
successive one-year terms unless either party gives three months prior notice of
non-renewal.  Under  the  Agreement,  Dr.  Riesenfeld  devotes  his full time to
serving as  President of the Company.  Dr.  Riesenfeld's  annual gross salary is
$175,000.

     Robert W. Cook.  In 1998,  the Company  entered into a one-year  employment
agreement  with  Mr.  Cook,  which is  automatically  renewable  for  successive
one-year  terms unless the Company gives 90 days' prior written  notice,  or Mr.
Cook gives 60 days' prior written notice,  of non-renewal.  Under the Agreement,
Mr. Cook devotes his full time to serving as Vice President -- Finance and Chief
Financial Officer of the Company. Mr. Cook's annual gross salary is $165,000.

     Directors'   Compensation.   In  1997,   Directors   did  not  receive  any
compensation for service on the Board or for attending Board meetings.


           COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

     The members of the  Compensation  and Stock  Option  Committee in 1997 were
Messrs.  Loeb and Grinstead.  Prior to the Merger (October  1992),  Mr. Loeb was
Chairman  of  the  Board  of  the  Company.  There  were  no  interlocks  on the
Compensation and Stock Option Committee in 1996.


                                      -14-

<PAGE>



                                PERFORMANCE GRAPH

     The following graph compares the Company's cumulative  stockholder's return
for the five year  period  ended  December  31, 1997 with the  cumulative  total
return of the NASDAQ  Equity Market Index and the NASDAQ  Pharmaceuticals  Index
over the same period.

 [THE FOLLOWING TABLE WAS REPRESENTED BY A LINE CHART IN THE PRINTED MATERIAL.]


<TABLE>
<CAPTION>
For 1998 Proxy:


                                        1992          1993          1994            1995           1996         1997
                                        ----          ----          ----            ----           ----         ----
<S>                                    <C>           <C>           <C>             <C>            <C>          <C>   
Nasdaq Composite                       100.00        114.80        112.22          158.70         195.19       239.52
Nasdaq Pharmaceuticals                 100.00         89.13        67.019          122.72         123.07       127.18
Pharmos Corporation                    100.00         65.63         11.43           12.24          12.24        16.66
</TABLE>



                                      -15-

<PAGE>



                TRANSACTIONS AND/OR INDEBTEDNESS WITH MANAGEMENT

None.


                               SECTION 16 FILINGS

     No person  who,  during the fiscal  year ended  December  31,  1997,  was a
director,  officer or beneficial owner of more than ten percent of the Company's
Common Stock [which is the only class of  securities  of the Company  registered
under  Section  12 of the  Securities  Exchange  Act of  1934  (the  "Act")],  a
"Reporting  Person",  failed  to file on a timely  basis,  reports  required  by
Section 16 of the Act during the most recent fiscal year. The foregoing is based
solely  upon a review by the  Company  of Forms 3 and 4 during  the most  recent
fiscal year as furnished to the Company under Rule  16a-3(d)  under the Act, and
Forms 5 and amendments thereto furnished to the Company with respect to its most
recent  fiscal  year,  and any  representation  received by the Company from any
reporting person that no Form 5 is required.

                                      -16-

<PAGE>




           ITEM 2 -  PROPOSAL TO APPROVE THE ISSUANCE OF CERTAIN SHARES
           OF COMMON STOCK ON CONVERSION OF SERIES C PREFERRED STOCK

Background

     Creation of C Preferred and Warrants

     The Board of  Directors  on January 30, 1998 created a new series of 10,000
shares  of  Series  C  Convertible   Participating   Preferred   Stock  (the  "C
Preferred").  A copy of the  Designations,  Preferences  and  Rights of Series C
Convertible   Preferred  Stock  of  Pharmos  Corporation  (the  "Certificate  of
Designation") which created the C Preferred is attached hereto as Exhibit A. The
summary of the terms of the C Preferred in this Proxy  Statement is qualified in
its entirety by the terms set forth in the Certificate of Designation.

     Each share of C Preferred has a face value of $1,000 per share, and accrues
a  premium  at 5% per annum  for  conversion  purposes  (the  "Premium").  The C
Preferred  was not  convertible  during the 60-day period from February 3, 1998,
the first date of issuance of shares of Series C Preferred, until April 4, 1998.
From that date until  August 2, 1998,  the C Preferred  was  convertible  into a
number  of  shares  of  Common  Stock  equal to (i)  $1,000  (ii)  divided  by a
conversion  price which equals 90% of the average of the low trade prices of the
Common  Stock for the five  consecutive  trading  days ending on the trading day
immediately  preceding the conversion date (the "Variable Conversion Price"). On
or after  August 2,  1998,  the  conversion  price  will  equal the lower of the
Variable Conversion Price or a price equal to 120% of the average of the closing
bid prices of the Common  Stock for the trading  days  beginning on July 4, 1998
and ending on August 2, 1998.

     Upon the  occurrence  of  certain  events,  the  conversion  formula  for C
Preferred  is  adjusted.  For  example,  if the Company  publicly  announces  an
intention to merge or sell its assets, or if a third party publicly  announces a
tender offer for at least 50% of the Company's  outstanding  Common  Stock,  the
conversion price of the C Preferred is the lesser of (x) the conversion price as
normally  calculated  and  (y)  the  conversion  price  which  would  have  been
applicable for a conversion  occurring on the date such public  announcement was
made by the Company or the third party. In addition,  if the Company is acquired
by another entity, and the securities received by the Company's shareholders are
not publicly  traded or are thinly  traded,  the holders of the C Preferred  are
entitled  to receive  the  greater of (i) the number of shares of the  surviving
entity they would have received had they  converted  their shares of C Preferred
on the  trading  date  immediately  prior  to  the  public  announcement  of the
acquisition or (ii) 125% of the face amount of the C Preferred (that is, 125% of
$1,000 per share, or $1,125).

     The C Preferred  automatically  converts  into Common  Stock on February 3,
2001 if the Registration  Statement (as defined below) is then effective and the
Company is then listed on the Nasdaq  National Market System or the Nasdaq Small
Cap Market ("Nasdaq"). The Certificate of

                                      -17-

<PAGE>



Designation  also  provides  for terms on which the  Company  may  redeem  the C
Preferred for cash.

     The face value of the C Preferred,  together with the Premium, is preferred
in  liquidation  against the holders of Company's  Common Stock and other Junior
Securities (as defined). With certain exceptions,  the consent of the holders of
the C Preferred  is required  before the Company can issue  senior or pari passu
securities,  and for the  declaration  of dividends on any junior  stock.  The C
Preferred generally has no voting rights.

     The Certificate of Designation  provides for certain  penalties  (including
the accrual of certain  payment and mandatory  redemption at prices set forth in
the Certificate of Designation) if, among other things, the Company fails timely
to  effectuate  conversion  of  the C  Preferred  (whether  or  not  there  is a
sufficient  number  of  authorized  shares  of  Common  Stock  to  effectuate  a
conversion), if the Company is not listed on Nasdaq, if the effectiveness of the
Registration  Statement is suspended for a certain  period of time) or if, prior
to  February 3, 1999,  Dr. Haim Aviv ceases to hold the  position of Chairman of
the Board and Chief Executive  Officer of the Company,  other than reasons which
are not under his or the Company's control.

     In order to effectuate the placement the transaction referred to below, the
Board also authorized the issuance of five-year  warrants in the form of Exhibit
B to purchase  shares of Common Stock at $2.67 per share (the  "Warrants").  The
Warrants provide for anti-dilution  adjustments in certain events, including the
sale by the  Company  of  Common  Stock at less than the  exercise  price of the
Warrants. The summary of the terms of the Warrants set forth herein is qualified
in its  entirety by  reference  to the actual form of the  Warrants set forth in
Exhibit B.

     Nasdaq Rule 4310(25)(H)(i)(d) and Certain Required Redemptions

     NASDAQ  Rule   4310(25)(H)(i)(d)   (the  "Rule")   provides  (with  certain
exceptions  not relevant here) that,  without  shareholder  approval,  a company
listed on the Nasdaq Small Cap Market may not in any transaction  issue a number
of shares  equal to more than 20% of the  number of shares of Common  Stock then
outstanding.  Although the Rule was not in effect as of the initial  issuance of
the first 5,000 shares of C Preferred on February 3, 1998,  the Company,  in the
interests of caution, has taken the approach that the Rule is applicable to such
issuance  since all  conversions of the C Preferred have occurred and will occur
after the effectiveness of the Rule on February 23, 1998.

     As of February 3, 1998, there were outstanding  31,033,048 shares of Common
Stock of the  Company,  so that the Company on that date could  issue  6,206,609
shares under the Rule.  Accordingly,  the C Preferred  provides that, unless the
Company  obtains the approval of its  stockholders  to issue more than 6,206,609
shares under the Rule, the Company is to redeem, and is not to permit conversion
of, any shares of C Preferred whose conversion would otherwise cause the Company
to issue a total number of shares of Common Stock in excess of that permitted by
the Rule. The Company is required to give to each holder notice of redemption (a
"notice  of  redemption")  of the  shares  which  are  to be  redeemed  and  not
converted. The redemption price in

                                      -18-

<PAGE>



such circumstance is the greater of (x) 120% of the face amount of the shares of
C  Preferred  being  redeemed  (that is,  120% of $1,000,  or $1,200) or (y) the
product of (A) a fraction,  the numerator of which is the sum of the face amount
of the shares of C Preferred  being  redeemed,  the  Premium and any  applicable
penalty,  and the  denominator  of which is the applicable  conversion  price in
effect on the date of the notice of redemption  and (B) the average  closing bid
price  (without  any  discount)  during the period  beginning on the date of the
notice of redemption and ending on the date of redemption. The Company cannot at
this time determine the number of shares of C Preferred which it may be required
to redeem,  because the number of shares of Common Stock  issuable on conversion
of the C Preferred  depends in part on the market  price of the Common  Stock at
the time of conversion. Redemptions under this paragraph are referred to in this
Proxy Statement as Rule 4310(25)(H) Redemptions.

     The Company  has agreed in favor of the holders of the C Preferred  to seek
shareholder  approval  at the  Annual  Meeting  for the  issuance  of all shares
issuable  on  conversion  of the C  Preferred  in order that the  Company not be
required to make the redemption referred to in the preceding paragraph.  Proxies
for such approval are being solicited hereby.

     Issuance of C Preferred and Warrants

     On February 3, 1998,  the Company issued 5,000 shares of C Preferred to one
purchaser (the  "Purchaser").  The Company also issued to the purchaser  500,000
Warrants. The aggregate price of the securities sold was $5,000,000. The Company
paid a finder's  fee of $250,000  and issued  four-year  warrants to purchase an
aggregate  of  150,000  shares  at an  exercise  price  of  $2.28  per  share in
connection with this investment.  A copy of the Securities Purchase Agreement is
attached hereto as Exhibit C.

     The Purchaser agreed to purchase an additional 3,000 shares of C Preferred,
and  obtain  an  additional   300,000   Warrants,   for   additional   aggregate
consideration  of $3,000,000 (the "Second  Tranche") if certain  conditions were
satisfied by the Company, including obtaining approval from the US Food and Drug
Adminstration  for the  Company's  New  Drug  Application  (NDA) to  market  the
Company's  opthalmic   anti-inflammatory   drug,   Lotemax(TM).   All  necessary
conditions  have currently  been  satisfied by the Company,  but the Company has
elected not to close on the Second Tranche.

     The  Company  agreed  to  promptly  file  a  registration   statement  (the
"Registration  Statement")  at its  expense  to  register  the sale of shares of
Common Stock  issuable on  conversion  of the C Preferred and on exercise of the
Warrants  (as well as the  warrants  issued  to the  finder).  The  Registration
Statement was declared  effective by the Securities  and Exchange  Commission on
July 24, 1998.  The Company  also agreed that prior to August 3, 1998,  it would
not without  approval by the  Purchaser  make any  private  placement  of equity
securities  for cash,  except that no such approval was required for  placements
which  raised  funds for  acquisitions.  During the period from August 3 through
November 2, 1998, the Company may raise equity securities in a

                                      -19-

<PAGE>



private  placement  transaction,  but a registration of such  securities  cannot
become effective prior to November 3, 1998 without the Purchaser's approval.

Proposal and Considerations

     The Company  proposes  that the  shareholders  approve the  issuance of all
shares of Common  Stock which are issuable on  conversion  of the C Preferred in
order that the Company not be  required  to make Rule  4310(25)(H)  Redemptions.
Such redemptions  would require the expenditure of cash which could otherwise be
applied by the Company for corporate purposes.

     THE BOARD OF  DIRECTORS  UNANIMOUSLY  RECOMMENDS  A VOTE FOR THIS  PROPOSAL
(ITEM 2 ON THE ENCLOSED PROXY CARD) TO APPROVE THE ISSUANCE OF CERTAIN SHARES OF
COMMON STOCK ON CONVERSION OF SERIES C PREFERRED STOCK.



        ITEM 3 - PROPOSAL TO ADOPT THE INCENTIVE AND NON-QUALIFIED STOCK
                                   OPTION PLAN

     The Board of Directors has adopted,  subject to  stockholder  approval,  an
amendment (the "Amendment") to the 1997 Incentive and Non-Qualified Stock Option
Plan ("1997  Plan")  authorizing  the issuance of an additional  400,000  shares
under such plan,  thereby  increasing  the aggregate  number of shares  issuable
under such plan from 600,000 to 1,000,000.

     To date,  options to purchase  500,000 shares of the Company's Common Stock
have  been  granted  under  the 1997  Plan and none of such  options  have  been
exercised or terminated.

     The  adoption  of the  Amendment  by the  Board  of  Directors  reflects  a
determination  by the  Board  that  ensuring  the  continued  availability  of a
sufficient  number  of  options  available  for  grant  under  the 1997  Plan is
important to the Company's ongoing and continuing  efforts to attract and retain
key senior  management  personnel  and increase  the  interest of the  Company's
executive officers in the Company's continuing success.

     Since the  granting of options  under the 1997 Plan is  discretionary,  the
Company  cannot at present  determine the number of options that will be granted
in the  future to any  person  or group of  persons  or the terms of any  future
grant.  Future  option  grants and the terms  thereof will be  determined by the
Compensation Committee in accordance with the terms of the 1997 Plan.

     Set forth below is certain information  concerning the 1997 Plan. A copy of
the 1997 Plan is available upon written request to the Company.


                                      -20-

<PAGE>



Description of 1997 Plan

     The purpose of the 1997 Plan is to allow Directors, officers, key employees
and  consultants  of  the  Company  and  its   subsidiaries  to  increase  their
proprietary interest in, and to encourage such employees to remain in the employ
of, or maintain their  relationship  with,  such  entities.  It is intended that
options  granted  under the 1997 Plan will  qualify  either as  incentive  stock
options  under  Section  422 of the Code or an  non-qualified  options.  Options
granted under the 1997 Plan will only be exercisable for Common Stock.

     The 1997 Plan is  administered  by a  committee  appointed  by the Board of
Directors (the "Compensation Committee").  Members of the Compensation Committee
are not be eligible  to receive  options  while they are  members  except to the
extent  otherwise  permitted  under the  requirements  of Rule  16b-3  under the
Securities  Exchange Act of 1934.  The  Compensation  Committee  designates  the
persons to receive options,  the number of shares subject to the options and the
terms of the  options,  including  the  option  price and the  duration  of each
option, subject to certain limitations.

     The maximum  number of shares of Common Stock  available for issuance under
the 1997 Plan is  600,000  shares  (1,000,000  if the  Amendment  is  approved),
subject to adjustment in the event of stock splits,  stock  dividends,  mergers,
consolidations  and the like.  Common Stock subject to options granted under the
1997 Plan that expire or terminate  are available for options to be issued under
the 1997 Plan.

     The price at which shares of Common Stock may be purchased upon exercise of
an  incentive  stock  option must be at least 100% of the fair  market  value of
Common  Stock on the date the option is granted (or at least 110% of fair market
value in the case of a person holding more than 10% of the outstanding shares of
Common Stock (a "10% Stockholder")).

     The  aggregate  fair  market  value  (determined  at the time the option is
granted)  of Common  Stock with  respect to which  incentive  stock  options are
exercisable  for the first time in any  calendar  year by an optionee  under the
1997 Plan or any other  plan of the  Company or a  subsidiary,  shall not exceed
$100,000.  The  Compensation  Committee will fix the time or times when, and the
extent to  which,  an option is  exercisable,  provided  that no option  will be
exercisable  earlier  than one year or later  than ten  years  after the date of
grant (or five  years in the case of a 10%  Stockholder).  The  option  price is
payable in cash or by check. However, the Board of Directors may grant a loan to
an employee, pursuant to the loan provision of the 1997 Plan, for the purpose of
exercising  an option or may  permit  the  option  price to be paid in shares of
Common Stock at the then current fair market value, as defined in the 1997 Plan.

     Upon  termination of an optionee's  employment or consultancy,  all options
held  by  such  optionee  will  terminate,  except  that  any  option  that  was
exercisable on the date employment or consultancy  terminated may, to the extent
then  exercisable,  be exercised  within three  months  thereafter  (or one year
thereafter if the termination is the result of permanent and total disability

                                      -21-

<PAGE>



of the  holder),  and except  such three  month  period may be  extended  by the
Compensation  Committee in its  discretion.  If an optionee  dies while he is an
employee or a consultant or during such  three-month  period,  the option may be
exercised  within one year after death by the decedent's  estate or his legatees
or distributees, but only to the extent exercisable at the time of death.

     The 1997 Plan  provides  that  outstanding  options  shall  vest and become
immediately  exercisable in the event of a "sale" of the Company,  including (i)
the  sale of more  than  75% of the  voting  power  of the  Company  in a single
transaction  or a series of  transactions,  (ii) the sale of  substantially  all
assets of the Company,  (iii) approval by the stockholders of a  reorganization,
merger or  consolidation,  as a result of which the  stockholders of the Company
will own less  than  50% of the  voting  power  of the  reorganized,  merged  or
consolidated company.

     The Board of Directors may amend, suspend or discontinue the 1997 Plan, but
it must obtain stockholder approval to (i) increase the number of shares subject
to the 1997 Plan, (ii) change the  designation of the class of persons  eligible
to receive  options,  (iii)  decrease the price at which options may be granted,
except that the Board may, without stockholder  approval accept the surrender of
outstanding  options and authorize  the granting of new options in  substitution
therefor specifying a lower exercise price that is not less than the fair market
value of Common  Stock on the date the new option is  granted,  (iv)  remove the
administration of the 1997 Plan from the Compensation Committee,  (v) render any
member of the  Compensation  Committee  eligible to receive an option  under the
1997 Plan while  serving  thereon,  or (vi) amend the 1997 Plan in such a manner
that options issued under it intend to be incentive stock options,  fail to meet
the  requirements  of Incentive  Stock  Options as defined in Section 422 of the
Code.

     Under current  federal income tax law, the grant of incentive stock options
under the 1997 Plan will not result in any taxable income to the optionee or any
deduction  for the  Company at the time the options are  granted.  The  optionee
recognizes  no gain upon the exercise of an option.  However the amount by which
the fair  market  value of  Common  Stock at the time the  option  is  exercised
exceeds the option price is an "item of tax  preference" of the optionee,  which
may cause the  optionee  to be subject to the  alternative  minimum  tax. If the
optionee  holds the shares of Common Stock received on exercise of the option at
least one year from the date of  exercise  and two years from the date of grant,
he will be taxed at the time of sale at long-term  capital gains rates,  if any,
on the amount by which the proceeds of the sale exceed the option price.  If the
optionee  disposes of the Common  Stock before the  required  holding  period is
satisfied,  ordinary  income will  generally be recognized in an amount equal to
the excess of the fair market value of the shares of Common Stock at the date of
exercise  over the option  price,  or, if the  disposition  is a taxable sale or
exchange,  the amount of gain realized on such sale or exchange if that is less.
If, as permitted by the 1997 Plan, the Board of Directors permits an optionee to
exercise an option by delivering  already owned shares of Common Stock valued at
fair  market  value) the  optionee  will not  recognize  gain as a result of the
payment of the option price with such already  owned  shares.  However,  if such
shares were acquired  pursuant to the previous  exercise of an option,  and were
held less than one year after  acquisition  or less than two years from the date
of grant, the exchange will constitute a disqualifying  disposition resulting in
immediate taxation of the gain on

                                      -22-

<PAGE>



the already owned shares as ordinary  income.  It is not clear how the gain will
be computed on the  disposition of shares acquired by payment with already owned
shares.

     The  Company  is   currently   in   discussions   with   several   emerging
pharmaceutical  and  biotechnology  companies  about  potential  business and/or
product consolidations,  joint ventures, acquisitions, mergers or other business
combinations.  If any such  transaction is  consummated,  the existence of these
additional  outstanding  stock options under the 1997 Plan could have the effect
of reducing the aggregate  consideration  received by existing  stockholders  in
such transaction.

     THE BOARD OF  DIRECTORS  UNANIMOUSLY  RECOMMENDS  A VOTE FOR THE  AMENDMENT
(ITEM 3 ON THE ENCLOSED PROXY CARD)  INCREASING THE NUMBER OF SHARES  AUTHORIZED
FOR ISSUANCE  UNDER THE 1997  INCENTIVE  AND  NONQUALIFIED  STOCK OPTION PLAN BY
400,000 FROM 600,000 TO 1,000,000.


                         INDEPENDENT PUBLIC ACCOUNTANTS

     The Company has appointed Price  Waterhouse LLP as its  independent  public
accountants  to examine the financial  statements of the Company for the current
fiscal year. The selection of Price  Waterhouse LLP was approved by the Board of
Directors  prior to their  appointment.  Price  Waterhouse  LLP has  advised the
Company  that  they do not have any  material  financial  interests  in,  or any
connection with (other than as independent auditors, tax advisors and management
consultants), the Company.

     Price  Waterhouse  LLP is expected to be present at the Annual  Meeting and
will have the opportunity to make a statement, if they desire to do so, and they
are expected to be available to respond to appropriate questions.


                        STOCKHOLDERS' PROPOSALS FOR 1999
                         ANNUAL MEETING OF STOCKHOLDERS

     Proposals which  stockholders  intend to present at the 1998 annual meeting
of  stockholders  must be  received by the Company by May 1, 1999 to be eligible
for inclusion in the proxy material for that meeting.

                           ANNUAL REPORT ON FORM 10-K

     Upon  sending a written  request to  Pharmos  Corporation,  33 Wood  Avenue
South,  Suite 466,  Iselin,  NJ 08830,  Attention:  President,  stockholders may
obtain,  free of charge,  a copy of the Company's Annual Report on Form 10-K for
the fiscal year ended December 31, 1997, and any  amendments  thereto,  as filed
with the Securities and Exchange Commission.

                                      -23-

<PAGE>



                                  OTHER MATTERS

     As of the date of this Proxy Statement,  the only business which management
expects to be considered at the Annual  Meeting is the election of Directors and
the adoption of the incentive and non-qualified  stock option plan. If any other
matters come before the meeting, the persons named in the enclosed form of proxy
are expected to vote the proxy in  accordance  with their best  judgment on such
matters.

                                       BY ORDER OF THE BOARD OF DIRECTORS
                                                HAIM AVIV, PH.D.
                                             Chairman of the Board
Dated: August 17, 1998

1255/39/1998 Proxy

                                      -24-

<PAGE>



                                                                       EXHIBIT A



                      DESIGNATIONS, PREFERENCES AND RIGHTS
                                       OF
               SERIES C CONVERTIBLE PARTICIPATING PREFERRED STOCK
                                       OF

                               PHARMOS CORPORATION




                            I. DESIGNATION AND AMOUNT

     The designation (this  "Certificate of Designation") of this series,  which
consists  of  ten  thousand  (10,000)  shares  of  Preferred  Stock  of  Pharmos
Corporation,  a Nevada corporation (the "Company"),  is the Series C Convertible
Participating Preferred Stock (the "Preferred Stock") and the stated value shall
be One Thousand Dollars ($1,000.00) per share (the "Face Amount").

                                  II. DIVIDENDS

     The Preferred Stock will bear no dividends.

                            III. CERTAIN DEFINITIONS

     For purposes of this Certificate of Designation,  the following terms shall
have the following meanings:

     A. "Bankruptcy Event" shall mean any one or more of the following:  (i) the
commencement  of any  voluntary  proceeding  by the Company  seeking entry of an
order for relief under Title 11 of the United States Code or seeking any similar
or equivalent relief under any other applicable  federal or state law concerning
bankruptcy, insolvency, creditors' rights or any similar law; (ii) the making by
the Company of a general assignment for the benefit of its creditors;  (iii) the
commencement of any involuntary  proceeding respecting the Company seeking entry
of an order for relief  against  the  Company  in a case  under  Title 11 of the
United States Code or seeking any similar or  equivalent  relief under any other
applicable federal or state law concerning  bankruptcy,  insolvency,  creditors'
rights or any similar law, which  proceeding is not dismissed  within sixty (60)
days  after its  commencement;  (iv) entry of a decree or order  respecting  the
Company by a court  having  competent  jurisdiction,  which  decree or order (x)
results  in the  appointment  of a  receiver,  liquidator,  assignee,  examiner,
custodian,  trustee, sequestrator (or other similar official) for the Company or
for  any  substantial  part  of its  property  or (y)  orders  the  winding  up,
liquidation,   dissolution,   reorganization,    arrangement,   adjustment,   or
composition of the Company or any of its debts; (v) the voluntary appointment by
the Company of a receiver, liquidator, assignee, examiner,


<PAGE>



custodian,  trustee, sequestrator (or other similar official) for the Company or
for any  substantial  part of its property;  (v) the bringing of an  involuntary
action  for the  appointment  of a  receiver,  liquidator,  assignee,  examiner,
custodian,  trustee, sequestrator (or other similar official) for the Company or
for any  substantial  part of its property  which is not dismissed  within sixty
(60) days or which results in an  adjudication  or  appointment  or an order for
relief;  (vi) the failure by the Company to pay, or its  admission in writing of
its inability to pay, its debts generally as they become due; (vii) the exercise
by any creditor of any right in connection  with an interest of such creditor in
any substantial and material part of the Company's property,  including, without
limitation,  foreclosure  upon all or any such part of the  Company's  property,
replevin,  or the exercise of any rights or remedies  provided under the Uniform
Commercial  Code with  regard  thereto;  (viii) the  calling by the Company of a
general meeting of its creditors or any portion of them; (ix) the failure by the
Company to file an answer or other pleading denying the material  allegations of
any proceeding described herein that is filed against it; and (x) the consent by
the Company to any of the actions, appointments, or proceedings described herein
or the  failure  of the  Company  to  contest  in good  faith any such  actions,
appointments, or proceedings.

     B. "Closing Bid Price" means,  for any security as of any date, the closing
bid price of such  security  on the  principal  securities  exchange  or trading
market  where  such  security  is  listed or traded  as  reported  by  Bloomberg
Financial  Markets or a  comparable  reporting  service of  national  reputation
selected by the Company and  reasonably  acceptable  to holders of the Preferred
Stock (each, a "Holder") then holding a majority of the then outstanding  shares
of Preferred Stock ("Majority  Holders") if Bloomberg  Financial  Markets is not
then reporting closing bid prices of such security (collectively,  "Bloomberg"),
or if the  foregoing  does not  apply,  the  last  reported  sale  price of such
security in the over-the-counter market on the electronic bulletin board of such
security  as reported by  Bloomberg,  or, if no sale price is reported  for such
security by  Bloomberg,  the average of the bid prices of any market  makers for
such security as reported in the "pink sheets" by the National Quotation Bureau,
Inc. If the Closing Bid Price  cannot be  calculated  for such  security on such
date on any of the  foregoing  bases,  the Closing Bid Price of such security on
such  date  shall  be the  fair  market  value as  reasonably  determined  by an
investment banking firm selected by the Company and reasonably acceptable to the
Majority Holders, with the costs of such appraisal to be borne by the Company.

     C. "Conversion Date" means, for any Optional Conversion, the date specified
in the notice of conversion (the "Notice of Conversion"), so long as the copy of
the Notice of Conversion is faxed (or delivered by other means) to the Company's
Attorney  (as  defined  below)  (with a copy to the  Company)  before 6:00 p.m.,
Eastern time, on the Conversion  Date indicated in the Notice of Conversion.  If
the Notice of  Conversion  is not so faxed or  otherwise  delivered  before such
time,  then the Conversion  Date shall be the business day following the date on
which the Notice of  Conversion  is faxed (or  delivered  by other  means).  The
Conversion  Date for the Required  Conversion at Maturity  shall be the Maturity
Date (as such  terms are  defined  herein).  Copies  of  Notices  of  Conversion
delivered  to the Company  shall be delivered  to Pharmos  Corporation,  33 Wood
Avenue South, Suite 466, Iselin, New Jersey 08330 (Facsimile No.: 732-603-3532).
"Company's  Attorney"  shall mean Mr. Adam Eilenberg at  Ehrenreich,  Eilenberg,
Krause & Zivian,

                                       -2-

<PAGE>



LLP, 11 East 44th Street,  17th Floor,  New York, New York 10017 (Facsimile No.:
212-986-2399), or such other attorney as Holders are notified of in writing from
time to time by the Company.

     D. "Conversion  Price" means, with respect to any Conversion Date occurring
(i) during the period  ending one hundred and eighty  (180) days  following  the
date of  original  issuance  of the  Preferred  Stock (the  "Initial  Conversion
Period"),  the Variable  Conversion Price, and (ii) after the Initial Conversion
Period,  the lower of the Fixed  Conversion  Price and the  Variable  Conversion
Price, subject to adjustment as provided herein.

     E. "Fixed  Conversion Price" means one hundred and twenty percent (120%) of
the average of the Closing  Bid Prices of the common  stock,  $.03 par value per
share, of the Company (the "Common Stock") for the trading days beginning on the
date which is one hundred and fifty-one (151) days, and ending on the date which
is one hundred and eighty (180) days, following the First Closing (as defined in
the  Securities  Purchase  Agreement)  (subject to equitable  adjustment for any
stock splits,  stock dividends,  reclassifications or similar events during such
period)

     F. "Premium" means 1000 x (N/365) x (.05).

                  N      = the number of days from the applicable Closing to,
                           and including, the Conversion Date.

     G. "Low Trade Price"  means,  for any  security as of any date,  the lowest
trade price of such  security on the  principal  securities  exchange or trading
market where such security is listed or traded as reported by  Bloomberg,  or if
the foregoing  does not apply,  the low reported trade price of such security in
the over-the-counter market on the electronic bulletin board of such security as
reported by  Bloomberg,  or, if no sale price is reported  for such  security by
Bloomberg,  the low  trade  price of any  market  makers  for such  security  as
reported in the "pink sheets" by the National Quotation Bureau, Inc.

     H. "Variable Conversion Price" means, as of any Conversion Date, 90% of the
average of the Low Trade Prices of the Common Stock for the five (5) consecutive
trading days ending on the trading day immediately preceding the Conversion Date
(subject  to  equitable  adjustment  for  any  stock  splits,  stock  dividends,
reclassifications  or  similar  events  during  the such  five (5)  trading  day
period), subject to adjustment as provided herein.

     I. "NASDAQ Trigger Date" means the fifth (5th) day of any five  consecutive
trading  days during which the number of shares of Common  Stock  issuable  upon
conversion of all shares of Preferred Stock and upon the issuance of the Warrant
Shares (as defined in the  Securities  Purchase  Agreement  (as defined  below))
exceeds sixty-six and two-thirds  percent (66 2/3%) of the Cap Amount (as herein
defined).


                                       -3-

<PAGE>



                                 IV. CONVERSION

     A.  Conversion at the Option of the Holder.  Subject to the  limitations on
conversions  contained  in Section  IV.G,  each Holder may, at any time and from
time to time  beginning on the earlier of (i) the sixtieth  (60th) day after the
First Closing, (ii) the effectiveness of a registration statement of the Company
under the  Securities  Act of 1933,  as amended,  and the rules and  regulations
thereunder, or any similar successor statute (collectively the "Securities Act")
as contemplated by the Registration Rights Agreement,  (iii) the occurrence of a
material adverse change or development in the business, properties,  operations,
financial  condition,  operating  results or  prospects  of the  Company and its
subsidiaries,  taken as a whole on a  consolidated  basis (a  "Material  Adverse
Change"), (iv) the occurrence of a Bankruptcy Event, and (v) the occurrence of a
Redemption Event (as herein defined)  convert (an "Optional  Conversion") any or
all of  its  shares  of  Preferred  Stock  into  a  number  of  fully  paid  and
non-assessable  shares of Common Stock  determined,  for each share of Preferred
Stock so to be converted, in accordance with the following formula:


                                (Premium + 1000)
                                ----------------
                                Conversion Price

     B. Mechanics of Conversion.  In order to effect an Optional  Conversion,  a
Holder shall fax (or otherwise  deliver) a copy of the fully executed  Notice of
Conversion  in the form  attached  hereto as  Schedule  1 to the  Company.  Upon
receipt by the Company of the fax copy of a Notice of Conversion  from a Holder,
the  Company or the  Company's  Attorney  (any such  confirmation  notice by the
Company's  Attorney shall be binding upon the Company) shall  immediately  send,
via fax, a confirmation to such Holder stating that the Notice of Conversion has
been  received,  the date upon which the  Company  expects to deliver the Common
Stock  issuable  upon such  conversion  and the name and  telephone  number of a
contact person at the Company  regarding the  conversion.  No later than one (1)
business  day  after  receipt  of such  confirmation  of  receipt  to  Notice of
Conversion the Holder shall  surrender or cause to be surrendered to a reputable
overnight  courier for next business day delivery (two (2) business day delivery
if from outside the United States) to the Company, the certificates representing
the  Preferred  Stock  being  converted  (the  "Preferred  Stock  Certificates")
accompanied by duly executed stock powers and a copy of the Notice of Conversion
(or, in lieu thereof, materials contemplated by Section XIV.B., if applicable).

     C. Delivery of Common Stock Upon Conversion.  Upon the delivery of a Notice
of Conversion, the Company shall, no later than the later of (a) the third (3rd)
business day  following  the  Conversion  Date and (b) the day that is the first
business  day (two (2)  business  days  following  delivery if from  outside the
United  States)   following  the  date  of  delivery  of  the  Preferred   Stock
Certificates  by the  Holder in  accordance  herewith  (or  satisfaction  of the
provisions of Section XIV.B, if applicable) (the "Delivery Period"),  deliver to
the  Holder  (or at its  direction)  (x) that  number of shares of Common  Stock
issuable upon  conversion of such shares of Preferred  Stock being converted and
(y) a certificate representing the number of shares of Preferred Stock not being

                                       -4-

<PAGE>



converted,  if any. The person or persons  entitled to receive  shares of Common
Stock  issuable  upon such  conversion  shall be treated for all purposes as the
record holder of such shares at the close of business on the Conversion Date and
such  shares  shall  be  issued  and  outstanding  as of such  date.  In lieu of
delivering  physical  certificates  representing  the Common Stock issuable upon
conversion,  provided  the  Company's  transfer  agent is  participating  in the
Depository Trust Company ("DTC") Fast Automated Securities Transfer program (the
"FAST  Program"),  and further provided that the resale of such shares of Common
Stock is covered by a then effective  registration  statement if required by the
FAST Program,  upon request of a Holder,  the Company  shall use its  reasonable
efforts to cause its transfer agent to electronically  transmit the Common Stock
issuable  upon  conversion  to the Holder by  crediting  the account of Holder's
prime broker with DTC through its Deposit  Withdrawal Agent Commission  ("DWAC")
system.  The Company shall use its reasonable efforts to participate in the FAST
Program.


     D. Taxes.  The  Company  shall pay any and all taxes  (other than  transfer
taxes)  which may be imposed  with  respect to the  issuance and delivery of the
shares of Common Stock pursuant to conversion of the Preferred Stock.

     E. No Fractional  Shares.  No  fractional  shares of Common Stock are to be
issued upon the  conversion  of Preferred  Stock,  but the Company shall instead
round up to the next whole  number  the  number of shares of Common  Stock to be
issued upon such conversion.

     F.  Conversion  Disputes.  In the case of any  dispute  with  respect  to a
conversion,  the Company  shall  promptly  issue such number of shares of Common
Stock as are not disputed in accordance  with Sections IV.A and IV.C hereof.  If
such dispute involves the calculation of the Conversion Price, the Company shall
submit the disputed  calculations to an independent  accounting firm of national
standing,  reasonably  acceptable  to Holder and to the Company,  via  facsimile
within  three (3)  business  days of receipt of the  Notice of  Conversion.  The
accounting  firm shall  audit the  calculations  and notify the  Company and the
Holder  of the  results  no later  than two (2)  business  days from the date it
receives the disputed  calculations.  The accounting firm's calculation shall be
deemed  conclusive,  absent manifest error. The Company shall not be liable with
respect to penalties or premiums  which have accrued or are payable with respect
to such shares of Preferred Stock or Common Stock:  (a) for the first occurrence
in which  Company is the  non-prevailing  party in such a dispute if the Company
has a reasonable,  good faith basis for such dispute,  and (b) in all cases,  to
the extent that the Holder is the non-prevailing  party with respect to specific
shares of Preferred Stock or Common Stock which are the subject of such dispute.
The Company shall then issue the appropriate number of shares of Common Stock in
accordance with Sections IV.A and IV.C hereof.

     G. Limitation on  Conversions.  The conversion of shares of Preferred Stock
shall be subject to the following  limitations  (each of which limitations shall
be applied independently):

          (i) Cap Amount. Prior to Stockholder Approval (as herein defined),  in
     the event that Nasdaq Rule 4460(i) or any  successor  rule)  applies to the
     Company, unless otherwise permitted

                                       -5-

<PAGE>



     by the Nasdaq SmallCap Market,  or the Nasdaq National Market System if the
     Common Stock of the Company  trades on such  market,  in no event shall the
     Company be required to issue more shares of Common Stock upon conversion of
     the  Preferred  Stock and the  exercise of the  Warrants (as defined in the
     Securities  Purchase Agreement) than the maximum number of shares of Common
     Stock that the Company can without  stockholder  approval so issue pursuant
     to such rule or rules (the "Cap Amount"),  which, as of the date of initial
     issuance of shares of  Preferred  Stock and  Warrants,  shall be the amount
     indicated  to be the Cap  Amount  in the  officer's  certificate  delivered
     pursuant to the  Securities  Purchase  Agreement.  The Cap Amount  shall be
     allocated  pro-rata to the Holders as provided in Article XIV.C. A Holder's
     allocable  portion of the Cap Amount shall be  applicable to both shares of
     Preferred  Stock  and  Warrants  held by it and  shall be  applied  to such
     Preferred  Stock and  Warrants  on the basis of the time of  conversion  or
     exercise,  as the  case  may be,  thereof.  In the  event  the  Company  is
     prohibited from issuing shares of Common Stock as a result of the operation
     of this subparagraph (i), the Company shall comply with Article VIII.

          (ii) Five Percent Holdings.  Notwithstanding  anything to the contrary
     contained herein,  the Preferred Stock shall not be convertible by a Holder
     to the extent (but only to the extent) that, if convertible by such Holder,
     such Holder,  or any of its  affiliates (as defined under Rule 12b-2 of the
     Securities  Exchange Act of 1934, as amended),  would  beneficially  own in
     excess of 4.9% of the shares of Common  Stock.  To the extent the foregoing
     limitation  applies,  the determination of whether Preferred Stock shall be
     convertible  (vis-a-vis other securities owned by such Holder) and of which
     Preferred Stock shall be convertible  (as among shares of Preferred  Stock)
     shall  be in the  sole  discretion  of the  Holder  and  submission  of the
     Preferred  Stock  for  conversion  shall  be  deemed  to  be  the  Holder's
     determination  of whether such Preferred  Stock is  convertible  (vis-a-vis
     other  securities  owned by such  Holder) and of which  shares of Preferred
     Stock are convertible (as among shares of Preferred Stock), subject to such
     aggregate  percentage  limitation.  No prior inability to convert Preferred
     Stock  pursuant to this Section shall have any effect on the  applicability
     of  the   provisions  of  this  Section  with  respect  to  any  subsequent
     determination  of  convertibility.   For  the  purposes  of  this  Section,
     beneficial  ownership and all  determinations  and calculations,  including
     without limitation,  with respect to calculations of percentage  ownership,
     shall be made in accordance  with Section 13(d) of the Securities  Exchange
     Act  of  1934,  as  amended,  and  Regulation  13D  and G  thereunder.  The
     provisions of this Section may be implemented in a manner otherwise than in
     strict  conformity  with the terms of this Section with the approval of the
     Board of  Directors  of the Company and a Holder:  (i) with  respect to any
     matter to cure any ambiguity  herein,  to correct this  subsection  (or any
     portion  thereof) which may be defective or inconsistent  with the intended
     4.9% beneficial ownership limitation herein contained or to make changes or
     supplements  necessary or  desirable  to properly  give effect to such 4.9%
     limitation;  and (ii) with  respect to any other  matter,  with the further
     consent of the holders of majority of the then outstanding shares of Common
     Stock.  The  provisions  of this Section may be waived by any Holder at its
     election upon not less than  sixty-one  (61) days prior written notice from
     such Holder to the Company, including, without limitation, a limited waiver
     to  increase  the 4.9%  limit  herein  contained  to any  other  percentage
     specified by such Holder.  The limitations  contained in this Section shall
     apply to a  successor  Holder of  Preferred  Stock if,  and to the  extent,
     elected by such successor Holder  concurrently with its acquisition of such
     Preferred Stock,  such election to be promptly  confirmed in writing to the
     Company (provided no

                                       -6-

<PAGE>



     transfer or series of transfers to a successor  Holder or Holders  shall be
     used by a Holder to evade the limitations contained herein).

     H. Required Conversion at Maturity. Subject to the limitations set forth in
Section IV.G. and provided all shares of Common Stock  issuable upon  conversion
of all  outstanding  shares of Preferred  Stock and exercise of all  outstanding
Warrants (in each case, without giving effect to any limitation on conversion or
exercise) are then (i)  authorized  and reserved for issuance,  (ii)  registered
under the Securities Act of 1933, as amended (the  "Securities  Act") for resale
by all holders of such shares of Preferred Stock and Warrants, (iii) eligible to
be traded on either the  Nasdaq  National  Market  System,  the Nasdaq  SmallCap
Market,  the New York Stock Exchange or the American Stock Exchange,  each share
of  Preferred  Stock  outstanding  on the third (3rd)  anniversary  of the First
Closing (the  "Maturity  Date") (and any accrued and unpaid  Conversion  Default
Payments),  automatically shall be converted into shares of Common Stock on such
date in accordance  with the  conversion  formula set forth in Section IV.A (the
"Required Conversion at Maturity"), except as to any Holder who elects otherwise
in the event that a Bankruptcy  Event or Redemption  Event has occurred prior to
the Maturity  Date and shall be continuing  as of the Maturity  Date;  provided,
however,  that the  Maturity  Date will be  extended  for up to ninety (90) days
after the third  anniversary of the First Closing (the  "Extension  Period") and
the shares of Preferred  Stock shall be converted as provided herein at any time
during the Extension  Period if any failure to satisfy clauses (ii) and (iii) of
this sentence are satisfied for a continuous period of at least five (5) trading
days during the  Extension  Period and no Bankruptcy  Event or Redemption  Event
exists at any time  during such  period.  If a Required  Conversion  at Maturity
occurs,  the Company  and the Holders  shall  follow the  applicable  conversion
procedures  set forth in this Article IV;  provided,  however,  that a Notice of
Conversion shall be deemed to be delivered to the Company on the Maturity Date.


               V. RESERVATION OF AUTHORIZED SHARES OF COMMON STOCK

     A. Reserved Amount. The Company shall have authorized and reserved and keep
available  for  issuance  not  less  than ten  million  10,000,000  (subject  to
equitable adjustment for any stock splits, stock dividends,  reclassification or
similar  events) shares of Common Stock (the "Reserved  Amount")  solely for the
purpose of effecting the conversion of the Preferred Stock and the Warrants. The
Company shall at all times reserve and keep  available out of its authorized but
unissued shares of Common Stock a sufficient number of shares of Common Stock to
provide for the full conversion of all outstanding  Preferred Stock and exercise
of the  Warrants  and  issuance  of the  shares  of Common  Stock in  connection
therewith.  The Reserved Amount shall be allocated among the Holders as provided
in Section  XIV.C.  Notwithstanding  anything to the  contrary set forth in this
Agreement and  notwithstanding the ten (10) and ninety (90) day periods referred
to in clause (vi) of Section VIII.A. of this Certificate of Designation,  to the
extent the Company has authorized and unissued  shares of Common Stock which are
not  reserved  for  another  purpose,  such  shares  shall  be used  to  satisfy
conversions  of  Preferred  Stock and  exercise of the  Warrants and issuance of
shares of Common Stock in connection therewith.  In addition,  during any period
in which  the  Reserved  Amount is less than one  hundred  seventy-five  percent
(175%) of the number of shares of Common

                                       -7-

<PAGE>



Stock  issuable  on  five  consecutive  trading  days  upon  conversion  of  the
outstanding  Preferred Stock and exercise of the then  outstanding  Warrants (in
each case without  giving  effect to any  limitation  on  conversion or exercise
thereof),  the Company shall not reserve shares of Common Stock for any purposes
other than the conversion of the Preferred Stock or the exercise of the Warrant.

     B. Increases to Reserved  Amount.  Without  limiting any other provision of
this Article V, if the Reserved Amount for any five (5) consecutive trading days
(the last of such five (5) trading days being the "Authorization  Trigger Date")
is less than one hundred fifty percent  (150%) of the number of shares of Common
Stock issuable on such trading days upon conversion of the outstanding Preferred
Stock and exercise of the then outstanding Warrants (in each case without giving
effect to any  limitation on  conversion  or exercise  thereof) then the Company
shall  immediately  notify the Holders of such occurrence and shall  immediately
take all  necessary  action  (including  stockholder  approval to authorize  the
issuance of additional  shares of Common Stock) to increase the Reserved  Amount
to one hundred and seventy-five percent (175%) of the number of shares of Common
Stock issuable upon conversion of the  outstanding  Preferred Stock and exercise
of all  outstanding  Warrants  (in  each  case,  without  giving  effect  to any
limitation  on conversion or exercise  thereof)  (the "Reset  Reserved  Amount);
provided,  however,  that following the date on which the Company has authorized
and reserved and made  available  for issuance the Reset  Reserved  Amount,  the
provisions  of this  Article V shall be reset and any  subsequent  Authorization
Trigger  Date  shall  occur only if the Reset  Reserved  Amount for any five (5)
consecutive  trading days is less than one hundred and fifty  percent  (150%) of
the  number of  shares  of  Common  Stock  issuable  on such  trading  days upon
conversion  of the  outstanding  Preferred  Stock and the  exercise  of the then
outstanding  Warrants (in each case without  giving effect to any  limitation or
conversion or exercise thereof).

                   VI. COMPLIANCE WITH CAP AMOUNT RESTRICTIONS

     A. Share Authorization.  The Company shall, on or before each of (a) thirty
days following each NASDAQ Trigger Date and (b) unless Stockholder  Approval (as
herein  defined) has already been  obtained,  the date one hundred  twenty (120)
days  after the date of the First  Closing  (each  such  date,  a "Proxy  Filing
Deadline"),  prepare and file with the  Securities  and Exchange  Commission  an
appropriate proxy statement (which complies with U.S. federal securities law) in
order to solicit by proxy the  authorization  by the stockholders of the Company
(such  stockholder  approval,  when obtained,  being defined as the "Stockholder
Approval")  of the issuance of shares of Common Stock upon  conversion of shares
of Preferred Stock pursuant to the terms hereof and the exercise of the Warrants
pursuant to the terms  thereof in the aggregate in excess of twenty (20) percent
of the  outstanding  shares of Common  Stock and to eliminate  any  prohibitions
under the rules or  regulations  of any stock  exchange,  interdealer  quotation
system or other self-regulatory  organization with jurisdiction over the Company
or any of its  securities  on the  Company's  ability to issue  shares of Common
Stock in excess of the Cap Amount. The Company shall submit all such matters for
which   Stockholder   Approval  is  required  to  its   Stockholders  for  their
authorization  and  approval on or before sixty (60) days after any Proxy Filing
Deadline  and shall use its best  efforts to obtain  Stockholder  Approval on or
before ninety (90) days after such Proxy Filing Deadline.

                                       -8-

<PAGE>



     B. Obligation to Notify.  If at any time a NASDAQ Trigger Date occurs,  the
Company shall immediately notify the Holders of such occurrence.


                       VII. FAILURE TO SATISFY CONVERSIONS

     A.  Conversion  Default  Payments.  If, at any time, (x) a Holder submits a
Notice of  Conversion  (or is deemed to submit such  notice  pursuant to Section
IV.H) and the Company  fails for any reason  (other than because  such  issuance
would exceed such Holder's  allocated  portion of the Reserved Amount or the Cap
Amount,  for which  failure the  Holders  shall have the  remedies  set forth in
Article VIII) to deliver,  on or prior to the expiration of the Delivery  Period
for such conversion,  such number of shares of Common Stock to which such Holder
is entitled upon such conversion,  or (y) the Company provides notice (including
by way of public announcement) to any Holder at any time of its intention not to
issue  shares of Common  Stock upon  exercise  by any  Holder of its  conversion
rights in accordance  with the terms of this  Certificate of Designation  (other
than because such issuance would exceed such Holder's  allocated  portion of the
Reserved  Amount or the Cap  Amount)  (each of (x) and (y)  being a  "Conversion
Default"),  then the Company shall pay to the affected Holder,  in the case of a
Conversion  Default  described in clause (x) above,  and to all Holders,  in the
case of a Conversion  Default  described in clause (y) above, an amount equal to
one thousand dollars  ($1,000)for each day such Conversion  Default exists until
the fifth (5th)  business day  following the receipt by facsimile by the Company
of the  Notice of  Conversion.  If,  following  the  fifth  (5th)  business  day
following  receipt by facsimile by the Company of the Notice of Conversion,  the
Company  continues to fail for any reason to deliver such shares of Common Stock
to which such Holder is entitled  upon such  conversion,  then the Company shall
pay to the affected  Holder,  in the case of a Conversion  Default  described in
clause  (x)  above,  and to all  Holders,  in the case of a  Conversion  Default
described  in clause (y) above,  an amount  equal to (i) one percent (1%) of the
Face Amount of the Preferred Stock with respect to which the Conversion  Default
exists  (which  amount  shall be deemed to be the  aggregate  Face Amount of all
outstanding  Preferred  Stock in the case of a Conversion  Default  described in
clause (y)  above) for each day such  Conversion  Default  exists  (ii) plus any
Premium.

     The payments to which a Holder  shall be entitled  pursuant to this Section
VII.A are  referred  to  herein as  "Conversion  Default  Payments."  Conversion
Default  Payments shall be made the fifth (5th)  business day following  written
demand by a Holder for payment  therefor and  otherwise in  accordance  with and
subject to the provisions of Section  XIV.E.  "Cure Date" means (i) with respect
to a Conversion Default described in clause (x) of its definition,  the date the
Company  effects the conversion of the portion of the Preferred  Stock submitted
for conversion and (ii) with respect to a Conversion Default described in clause
(y) of its  definition,  the date the  Company  undertakes  in  writing to issue
Common Stock in satisfaction of all conversions of Preferred Stock in accordance
with the terms of this Certificate of Designation  (provided the Company in fact
thereafter so satisfies such conversions).



                                       -9-

<PAGE>



     B.  Repayment  Option.  If a Holder has not received  certificates  for all
shares  of Common  Stock on or before  the tenth  (10th)  day after  receipt  by
facsimile by the Company of the Notice of Conversion  for any reason (other than
because  such  issuance  would  exceed such  Holder's  allocated  portion of the
Reserved Amount or the Cap Amount,  for which failure the Holders shall have the
remedies  set forth in Article  VIII,  or because such Holder has failed to meet
the  requirements  of Section IV.B which require the delivery of certificates or
the  satisfaction of Section  XIV.B),  then the affected Holder in the case of a
Conversion Default of the type described in clause (x) of Section VII.A, and all
Holders, in the case of a Conversion Default of the type described in clause (y)
of Section VII.A,  shall have the option (the "Repayment  Option"),  exercisable
within  thirty  (30)  days  from the date  upon  which  the  Company  is in full
compliance with this Certificate of Designation,  including, without limitation,
payment of all  Conversion  Default  Payments and payment of any and all damages
owed to Holder,  by delivery of a written notice to the Company (the  "Repayment
Option  Notice"),  to  receive  repayment,  in  cash,  of all of the  shares  of
Preferred  Stock  held by such  Holders,  in the  case of a  Conversion  Default
described  in  clause  (y) of  Section  VII.A  above,  or any of the  shares  of
Preferred Stock which are subject to a Conversion  Default held by such Holders,
in the case of a Conversion  Default  described  in clause (x) of Section  VII.A
above,  at a price per share of one hundred and fifty percent (150%) of the Face
Amount of the  Preferred  Stock plus any accrued  penalties  pursuant to Section
VII.A to the date of such  repayment;  provided,  however,  that if prior to the
date of delivery to the Company of a Repayment  Option  Notice and no later than
seven (7) days from the expiration of the Delivery  Period,  the Holder receives
certificates  for all shares of Common  Stock,  then the  Repayment  Option with
respect to such Holder  shall be  suspended  until such time as Holder again has
not received  certificates for all shares of Common Stock on or before the tenth
(10th) day after receipt by facsimile by the Company of the Notice of Conversion
for any reason  (other than because  such  issuance  would exceed such  Holder's
allocated  portion of the Reserved  Amount or the Cap Amount,  for which failure
the Holders shall have the remedies set forth in Article  VIII).  A Holder shall
provide the Company written notification  indicating any amounts payable to such
Holder  pursuant to this Section VII.B.  Such payments shall be made within five
(5)  business  days of the  Company's  receipt of such notice and  otherwise  in
accordance with and subject to the provisions of Section XIV.


                     VIII. REDEMPTION DUE TO CERTAIN EVENTS

     A. Redemption Events. A "Redemption Event" means any one of the following:

          (a) the  Common  Stock (or any  portion  thereof)  is  suspended  from
     trading on any of, or is not listed (and authorized) for trading on any of,
     the Nasdaq National Market System, the Nasdaq SmallCap Market, the American
     Stock Exchange, or the New York Stock Exchange for an aggregate of five (5)
     trading days in any nine (9) month period;

          (b) the Company fails, and any such failure  continues uncured for ten
     (10) days after the  Company  has been  notified  thereof in writing by the
     Holder,  to remove any restrictive  legend on any certificate or any shares
     of Common Stock issued to the Holders of Preferred Stock

                                      -10-

<PAGE>



     or Warrants upon conversion of the Preferred Stock or Warrants (as the case
     may be) as and  when  required  by this  Certificate  of  Designation,  the
     Securities Purchase Agreement,  dated  contemporaneously  herewith,  by and
     among  the  Company  and the other  signatories  thereto  (the  "Securities
     Purchase   Agreement"),   or  the  Registration  Rights  Agreement,   dated
     contemporaneously  herewith,  by  and  among  the  Company  and  the  other
     signatories  thereto  (the  "Registration  Rights  Agreement"),   it  being
     understood  and  agreed  that  the   provisions  of  this   Certificate  of
     Designation  and such agreements with respect to the removal of restrictive
     legends  shall be strictly  construed in accordance  with the  requirements
     thereof;

          (c) the Company  materially  breaches any  material  covenant or other
     material term of this Certificate of Designation,  the Securities  Purchase
     Agreement,  the  Warrants or the  Registration  Rights  Agreement  and such
     breach  continues  for a period of ten (10)  business  days  after  written
     notice  thereof to the Company and no remedy is otherwise  available  under
     this Article VIII other than pursuant to this paragraph VIII(A);

          (d)  any  representation  or  warranty  of  the  Company  made  in any
     agreement, statement or certificate given in writing in connection with the
     issuance  of  the  Preferred  Stock  (including,  without  limitation,  the
     Warrants,  the Securities  Purchase  Agreement or the  Registration  Rights
     Agreement),  shall be false or misleading in any material respect when made
     and the breach of which has had or could  reasonably  be expected to have a
     material adverse effect on the Company or on the Holder with respect to its
     investment  in shares of  Preferred  Stock or  Warrants or shares of Common
     Stock issuable upon  conversion of the Preferred  Stock or upon exercise of
     the Warrants;

          (e) the Registration Statement required to be filed by the Corporation
     pursuant to the Registration  Rights  Agreement,  has not been filed within
     thirty (30) days of the First Closing or has not been declared effective by
     the one hundred and  eightieth  (180th) day  following the First Closing or
     such  Registration  Statement,  after being declared  effective,  cannot be
     utilized by the Holders of Preferred  Stock and the Warrants for the resale
     of all of their  Registrable  Securities  (as  defined in the  Registration
     Rights  Agreement) for a period of eight (8)  consecutive  business days or
     for an aggregate of more than twenty (20) days in any twelve month period;

               (i) the Company fails to increase the Reserved Amount: (A) within
          ten (10) days following an Authorization Trigger Date if such increase
          requires solely  approval of the Company's Board of Directors,  or (B)
          within  ninety (90) days  following an  Authorization  Trigger Date if
          such increase requires approval of the Company's shareholders;

               (ii) the Company fails to eliminate  the Cap Amount  prohibitions
          set forth herein  within  ninety (90) days  following any Proxy Filing
          Deadline;

               (iii)  the  Company  fails to  obtain  the  effectiveness  of any
          amendment  to an  existing  registration  statements  within  ten (10)
          business days or of any new registration  statement within twenty (20)
          business days following a Registration Trigger Date (as defined in the
          Registration  Rights  Agreement)  as  required  by Section  2.3 of the
          Registration Rights Agreement; or

                                      -11-

<PAGE>




               (iv) If, prior to the first  anniversary of the date of the First
          Closing,  Dr.  Haim Aviv ceases to hold the  position of Chairman  and
          Chief Executive  Officer of the Company,  other than for reasons which
          are not under his or the Company's control.

     B Redemption By Holder.  Upon the  occurrence of a Redemption  Event (other
than a Redemption Event set forth in clause (iii) of Section VIII.A. above which
has been cured by the Company), each Holder shall have the right to elect at any
time and from  time to time by  delivery  of a  Redemption  Notice  (as  defined
herein) to the Company to require the Company to purchase for cash for an amount
per share equal to the Redemption Amount (as defined herein), (i) in the case of
a Redemption  Event described in clause (i) through (iii) or (ix), any or all of
the then outstanding shares of Preferred Stock held by such Holder,  (ii) in the
case of a Redemption  Event  described in clause (vi), a portion of the Holder's
Preferred  Stock such that,  after giving effect to such purchase,  the Holder's
allocated  portion of the Reserved  Amount exceeds one hundred and  seventy-five
percent  (175%) of the total number of Common Stock issuable to such Holder upon
conversion  of its  Preferred  Stock and  exercise of its Warrants (in each case
without  giving effect to any  limitation on conversion or exercise with respect
thereto),  (iii) in the case of a Redemption  Event described in clause (vii), a
portion of the Holder's  Preferred Stock such that,  after giving effect to such
purchase,  the Holder's  allocated portion of the Cap Amount exceeds one hundred
and fifty  (150%) of the total  number of Common  Stock  issuable to such Holder
upon conversion of its Preferred Stock and exercise of its Warrant (in each case
without  giving effect to any  limitation on conversion or exercise with respect
thereto) and (iv) in the case of a Redemption  Event described in clause (viii),
a portion of the Holder's Preferred Stock such that, after giving effect to such
purchase,  the Holder's  allocated  portion of the  Registrable  Securities  (as
defined  in  the  Registration   Rights  Agreement)   exceeds  one  hundred  and
seventy-five  percent  (175%)  of the total  number  of  shares of Common  Stock
issuable to such Holder upon  conversion of its Preferred  Stock and exercise of
its Warrants (in each case without giving effect to any limitation on conversion
or exercise with respect thereto).

     C. Definition of Redemption Amount. The "Redemption Amount" with respect to
a share of Preferred Stock means an amount equal to the greater of (i) 1.2 times
the  aggregate  Face Amount of the  Preferred  Stock for which a demand is being
made and (ii) an amount determined by the following formula:


                        Face Amount + Premium + Penalty   
                        -------------------------------   
                                       C P                             X    M 

    where:

     "CP"  means the  Conversion  Price in effect on the date of the  Redemption
Notice; and

     "M" means the  average of the  closing  bid price of the  Company's  Common
Stock  during  the period  beginning  on the date of the  Redemption  Notice and
ending on the date of the  redemption,  as reported on the principal  securities
exchange or trading market on which the Common Stock is traded.

                                      -12-

<PAGE>


     "Penalty"  means the  Conversion  Default  penalty  referred  to in Section
VII.A.

     D.  Redemption  Defaults.  The  Company  shall pay a Holder the  Redemption
Amount,  in cash, with respect to each share of Preferred Stock which is subject
to a written notice electing such redemption (a "Redemption Notice") within five
(5) business days of the Company's  receipt of such  Redemption  Notice.  In the
event the Company is not able to purchase all of the shares of  Preferred  Stock
subject to  Redemption  Notices,  the Company  shall redeem  shares of Preferred
Stock  from  each  Holder  pro  rata,  based on the  total  number  of shares of
Preferred Stock included by such Holder in the Redemption Notice relative to the
total  number of shares of  Preferred  Stock in all of the  Redemption  Notices;
provided the foregoing shall not be deemed to limit the Company's  obligation to
purchase shares of Preferred Stock hereunder.

     E.  Additional Cap Amount  Remedies.  Upon a Redemption  Event described in
clause (vii) of Section VIII.A,  which is not cured by the Company within thirty
(30) days (after  taking into  account the ninety (90) day period  provided  for
therein),  any Holder who is so prohibited  from  converting its Preferred Stock
may,  notwithstanding the Cap Amount or restrictions with respect thereto, elect
any one or more of the following:  (i) require, with the consent of the Majority
Holders (including any shares of Preferred Stock held by the requesting Holder),
the Company to terminate the listing of its Common Stock on the Nasdaq  SmallCap
Market  and,  at  such  Holders'  election,  to list  the  Common  Stock  on the
over-the-counter  electronic  bulletin  board;  and (ii)  require the Company to
issue  shares  of  Common  Stock in  accordance  with  such  holder's  Notice of
Conversion at a conversion  price equal to the Conversion Price in effect on the
date of the  Holder's  written  notice to the Company of its election to receive
shares of Common Stock pursuant to this subparagraph  (ii); or (iii) require the
Company to issue shares of Common Stock in accordance  with such holder's Notice
of  Conversion  but at a Conversion  Price equal to the Closing Bid Price on the
day  before  the date of the  Holder's  written  notice  to the  Company  of its
election to receive shares of Common Stock pursuant to this subparagraph.

     F. Redemption at Company's Option.

          (a) So long as no  Redemption  Event shall have  occurred and provided
     the  Company is not in  material  violation  of its  obligations  under the
     Securities  Purchase  Agreement,  the Registration  Rights  Agreement,  the
     Pharmos Corporation Stock Purchase Warrants, or this Certificate,  then the
     Company shall have the right to redeem ("Redemption at Company's Election")
     all or any  portion of the then  outstanding  Preferred  Stock  (other than
     Preferred  Stock which is the subject of a Notice of  Conversion  delivered
     prior to the  delivery  date of the Optional  Redemption  Notice (as herein
     defined)) for the Optional  Redemption  Amount (as herein  defined),  which
     right  shall be  exercisable  in  accordance  with the  provisions  of this
     Section VIII.F at any time prior to the Maturity Date or, if applicable, at
     any time prior to the last day of the  Extension  Period,  but in any event
     only if and so long as the  Redemption  Condition  is satisfied on the date
     the Company  delivers the Optional  Redemption  Notice.  The  Redemption at
     Company's  Election  may only be  exercised  by the  Company  for  Optional
     Redemption  Amounts in increments of One Million  Dollars  ($1,000,000)  by
     delivery of an Optional Redemption Notice in accordance with the redemption
     procedures  set forth below;  provided,  however,  that the  Redemption  at
     Company's Election may be exercised for smaller amounts in the event of the
     Company's redemption of all of the outstanding

                                      -13-

<PAGE>



     Preferred  Stock.  Any  Redemption at Company's  Election  pursuant to this
     Section  VIII.F shall be made ratably  among  Holders in  proportion to the
     amount of Preferred Stock then outstanding.  Holders may convert all or any
     part of their Preferred Stock selected for redemption hereunder into Common
     Stock at the  Conversion  Price by delivering a Notice of Conversion to the
     Company at any time prior to the Effective  Time of  Redemption  (as herein
     defined).

          (i) The  "Optional  Redemption  Amount"  means an amount  equal to the
     number of shares of Preferred Stock being redeemed multiplied by:

                                   1.2 x A x M
                                   -----------
                                        CP

where:

     "A" means the Face Amount + Premium + Penalty  with  respect to such shares
of Preferred Stock being redeemed

     "CP"  means the  Conversion  Price in effect  on the  delivery  date of the
Optional Redemption Notice; and,

     "M" means the  average  Closing  Bid Price of the  Company's  Common  Stock
during the ten  consecutive  trading  day period  ending on the day  immediately
preceding  the date on which the  Optional  Redemption  Notice is  delivered  to
Holder.

          (ii) The  "Redemption  Condition"  shall be  satisfied  if the average
     Closing Bid Price  equals 200% or more of the Closing Bid Price on the date
     of the First Closing (as defined in the Securities  Purchase Agreement) for
     the ten (10)  consecutive  days  immediately  prior to the date the Company
     delivers the Optional Redemption Notice.

          (b) The Company  shall effect the  Redemption  at  Company's  Election
     under this Section  VIII.F by giving at least ten (10)  business days prior
     written notice (the  "Optional  Redemption  Notice"),  of the date on which
     such redemption is to become effective (the "Effective Time of Redemption")
     to Holders of Preferred  Stock  selected for  redemption at the address and
     facsimile number of such Holder appearing in the Company's register for the
     Preferred Stock. The Optional  Redemption  Notice shall indicate the shares
     of Preferred  Stock  selected for  redemption  and the Optional  Redemption
     Amount.  The  Optional  Redemption  Notice  shall be  deemed  to have  been
     delivered  to a Holder:  (i) if such fax is  received  by such holder on or
     prior to 3:00 p.m.  Chicago time, on the time and date of  transmission  of
     Company's  fax;  and (ii) if such fax is received by Holder after 3:00 p.m.
     Chicago time,  on the next business day following the date of  transmission
     of  Company's  fax;  provided  that,  for any  notice  required  under this
     subsection VIII.F(b) to be valid, a copy of such notice must be sent to the
     Holders on the same day by overnight courier.

          (c) The Company may not  deliver an  Optional  Redemption  Notice to a
     Holder  unless  on or  prior  to the  date of  delivery  of  such  Optional
     Redemption  Notice,  the Company shall have  deposited with an escrow agent
     reasonably satisfactory to such Holder, as a trust fund, cash

                                      -14-

<PAGE>



     sufficient  in amount to pay all amounts to which Holders are entitled upon
     such  redemption  pursuant to subsection (a) of this Section  VIII.F,  with
     irrevocable instructions and authority to such escrow agent to complete the
     redemption  thereof in accordance  with this Section  VIII.F.  Any Optional
     Redemption  Notice  delivered in accordance with the immediately  preceding
     sentence shall be accompanied by a statement  executed by a duly authorized
     officer of the escrow agent, certifying the amount of funds which have been
     deposited  with such  transfer  agent or escrow agent and that the transfer
     agent or escrow agent has been  instructed  and agrees to act as redemption
     agent hereunder.

          (d) The Optional  Redemption Amount shall be paid to each Holder whose
     Preferred  Stock is being  redeemed at the  Effective  Time of  Redemption;
     provided,  however,  that the Company shall not be obligated to deliver any
     portion of the  Optional  Redemption  Amount to a Holder  until either such
     Holder  delivers  the  Preferred  Stock being  prepaid to the office of the
     Company or the  transfer  agent as  provided  in this  subsection,  or such
     Holder notifies the Company or the transfer agent that such Preferred Stock
     has been lost, stolen or destroyed and delivers documentation in accordance
     with Section XIV.B hereof. Notwithstanding anything herein to the contrary,
     in the event that the shares of  Preferred  Stock  being  redeemed  are not
     delivered  to the Company or the  transfer  agent,  the  redemption  of the
     Preferred  Stock  pursuant  to this  Section  VIII.F  shall still be deemed
     effective  as  of  the  Effective  Time  of  Redemption  and  the  Optional
     Redemption  Amount  shall be paid to each Holder whose  Preferred  Stock is
     being  redeemed  by 5:00  p.m.,  Chicago  time,  on the next  business  day
     following  the date on which the  shares of  Preferred  Stock are  actually
     delivered to the Company or the transfer agent.

          (e) If the  Company  fails to pay,  when due and owing,  any  Optional
     Redemption  Amount,  then each  Holder  entitled to receive  such  Optional
     Redemption  Amount shall have the right, at any time and from time to time,
     to require the Company,  upon written  notice,  to immediately  convert (in
     accordance  with the terms of Section  VIII.E) any or all of the  Preferred
     Stock which is the subject of Redemption at Company's  Election into shares
     of Common Stock at the lowest  Conversion Price in effect during the twenty
     (20) consecutive trading days following the Effective Time of Redemption.


                             IX. RANK; PARTICIPATION

     A. Rank.  All  shares of the  Preferred  Stock  shall rank (i) prior to the
Common  Stock;  (ii)  pari  passu  with all  shares  of the  Company's  Series B
Preferred  Stock,  prior to any other class of Capital  Stock of the Company now
outstanding  and prior to any class or series of  capital  stock of the  Company
hereafter created  (collectively,  with the Common Stock, "Junior  Securities");
(iii)  pari  passu  with any  class or series of  capital  stock of the  Company
hereafter  created  specifically  ranking,  by its  terms,  on  parity  with the
Preferred Stock (the "Pari Passu  Securities");  and (iv) junior to any class or
series of capital  stock of the Company  hereafter  created (with the consent of
the Holders  obtained in accordance  with Article XIII hereof,  provided that no
such consent  shall be required  from and after the date on which less than five
percent (5%) of the  originally  issued  Preferred  Stock  remains  outstanding)
specifically  ranking,  by its terms, senior to the Preferred Stock (the "Senior
Securities"),  in each  case as to  distribution  of  assets  upon  liquidation,
dissolution or winding up of the Company, whether voluntary or involuntary.

                                      -15-

<PAGE>



     B.  Participation.  Subject to the rights of the  holders  (if any) of Pari
Passu  Securities  and  Senior  Securities,  the  Holders  shall,  as Holders of
Preferred  Stock, be entitled to such dividends paid and  distributions  made to
the holders of Common Stock to the same extent as if such Holders had  converted
such  Preferred  Stock into Common Stock (without  regard to any  limitations on
conversion herein or elsewhere  contained) and had such Common Stock been issued
on the day before the record date for said  dividend or  distribution.  Payments
under the preceding  sentence  shall be made  concurrently  with the dividend or
distribution to the holders of Common Stock.

                            X. LIQUIDATION PREFERENCE

     A.  Liquidation of the Company.  If a Bankruptcy  Event shall occur and, on
account of any such event, the Company shall liquidate,  dissolve or wind up, or
if the Company shall  otherwise  liquidate,  dissolve or wind up (a "Liquidation
Event"),  no distribution  shall be made to the Holders of any shares of capital
stock  of  the  Company  (other  than  Senior   Securities)  upon   liquidation,
dissolution  or winding up unless prior  thereto the Holders shall have received
the Liquidation  Preference (as herein defined) with respect to each share.  If,
upon the occurrence of a Liquidation  Event,  the assets and funds available for
distribution  among the Holders and  holders of Pari Passu  Securities  shall be
insufficient to permit the payment to such Holders of the  preferential  amounts
payable  thereon,  then the  entire  assets  and  funds of the  Company  legally
available for  distribution to the Preferred Stock and the Pari Passu Securities
shall be  distributed  ratably among such shares in proportion to the ratio that
the  Liquidation  Preference  payable on each such share bears to the  aggregate
Liquidation Preference payable on all such shares.

     B.  Certain  Acts Not a  Liquidation.  The  purchase or  redemption  by the
Company of stock of any class,  in any manner  permitted by law,  shall not, for
the purposes hereof, be regarded as a liquidation,  dissolution or winding up of
the Company. Neither the consolidation or merger of the Company with or into any
other entity nor the sale or transfer by the Company of less than  substantially
all of its assets shall, for the purposes hereof, be deemed to be a liquidation,
dissolution or winding up of the Company.

     C. Definition of Liquidation Preference.  The "Liquidation Preference" with
respect to a share of  Preferred  Stock means an amount equal to the Face Amount
thereof plus the Premium with respect thereto plus any other amounts that may be
due  from  the  Company  with  respect   thereto   through  the  date  of  final
distribution.  The  Liquidation  Preference  with  respect  to  any  Pari  Passu
Securities shall be as set forth in the charter of the Company.

          XI. ADJUSTMENTS TO THE CONVERSION PRICE; CERTAIN PROTECTIONS

     The  Conversion  Price shall be subject to adjustment  from time to time as
follows:

     A. Stock Splits, Stock Dividends, Etc. If at any time on or after the First
Closing,  the number of  outstanding  shares of Common  Stock is  increased by a
stock split,  stock  dividend,  combination,  reclassification  or other similar
event, the Fixed Conversion Price shall be  proportionately  reduced,  or if the
number of  outstanding  shares of Common Stock is  decreased by a reverse  stock
split,  combination or  reclassification  of shares, or other similar event, the
Fixed Conversion Price shall be proportionately increased.

                                      -16-

<PAGE>



     B. Certain Public Announcements.  In the event that (i) the Company makes a
public  announcement  that it  intends  to  consolidate  or merge with any other
entity  (other than a merger in which the Company is the surviving or continuing
entity and its capital stock is unchanged and there is no distribution thereof))
or to sell or transfer all or substantially  all of the assets of the Company or
(ii) any person,  group or entity (including the Company)  publicly  announces a
tender  offer in  connection  with which such  person,  group or entity seeks to
purchase 50% or more of the Common Stock (the date of the announcement  referred
to in clause (i) or (ii) of this  paragraph  is  hereinafter  referred to as the
"Announcement  Date"),  and in either such event only if twenty percent (20%) or
more of the originally  issued  Preferred  Stock is then  outstanding,  then the
Conversion  Price shall,  effective  upon the  Announcement  Date and continuing
through the  consummation  of the proposed  tender offer or  transaction  or the
Abandonment  Date  (as  defined  below),  be  equal  to the  lesser  of (x)  the
Conversion  Price  calculated  as provided in Article IV and (y) the  Conversion
Price  which  would  have  been  applicable  for  Conversion  occurring  on  the
Announcement  Date. From and after the Abandonment Date, as the case may be, the
Conversion   Price  shall  be  determined  as  set  forth  in  Article  IV.  The
"Abandonment  Date" means with  respect to any  proposed  transaction  or tender
offer for which a public announcement as contemplated by this paragraph has been
made,  the date  which is seven (7)  trading  days after the date upon which the
Company (in the case of clause (i) above) or the person, group or entity (in the
case of clause (ii) above) publicly  announces the termination or abandonment of
the proposed  transaction  or tender offer which causes this paragraph to become
operative.

     C. Major Transactions.  If the Company shall consolidate with or merge into
any  corporation  as to which (a) the  common  stock or other  securities  to be
issued to the Company's holders of Common Stock (the "Exchange  Securities") are
not  publicly  traded,  (b) the average  daily  trading  volume of the  Exchange
Securities reported by Bloomberg during the ninety (90) day period ending on the
date on which such  transaction is publicly  disclosed is less than five hundred
thousand  dollars  ($500,000)  per day,  or (c) the  historical  one hundred day
volatility of the Exchange  Securities  reported by Bloomberg  during the period
ending on the date on which such transaction is publicly  disclosed is less than
sixty percent (60%) (a "Major  Transaction"),  then each Holder shall thereafter
be entitled to receive  consideration,  in exchange  for each share of Preferred
Stock held by it, equal to the greater of, as determined in the sole  discretion
of such Holder:  (i) the number of shares of stock or  securities or property of
the Company,  or of the entity resulting from such Major Transaction (the "Major
Transaction Consideration"), to which a Holder of the number of shares of Common
Stock  delivered  upon  conversion of such shares of Preferred  Stock would have
been entitled upon such Major  Transaction had the Holder exercised its right of
conversion  (without regard to any limitations on conversion herein or elsewhere
contained) on the trading date immediately  preceding the public announcement of
the  transaction  resulting in such Major  Transaction and had such Common Stock
been  issued and  outstanding  and had such  Holder been the holder of record of
such Common Stock at the time of the consummation of such Major Transaction, and
(ii) 125% of the Face Amount of such shares of Preferred  Stock in cash; and the
Company  shall  make  lawful  provision   therefor  as  a  part  of  such  Major
Transaction.  No sooner  than ten (10)  business  days nor  later  than five (5)
business days prior to the consummation of the Major Transaction,  but not prior
to the public announcement of such Major Transaction,  the Company shall deliver
written notice ("Notice of Major  Transaction") to each Holder,  which Notice of
Major  Transaction  shall be deemed to have been  delivered one (1) business day
after the Company's  sending such notice by fax (provided that the Company sends
a confirming copy of such notice on

                                      -17-

<PAGE>



the same day by  overnight  courier) of such Notice of Major  Transaction.  Such
Notice of Major  Transaction  shall  indicate  the  amount and type of the Major
Transaction  Consideration  which such Holder would  receive under clause (i) of
this  Section  XI.B.  If the Major  Transaction  Consideration  does not consist
entirely of United  States  currency,  such  Holder may elect to receive  United
States  currency  in an  amount  equal  to the  value of the  Major  Transaction
Consideration  in lieu of the  Major  Transaction  Consideration  by  delivering
notice of such  election to the Company  within  five (5)  business  days of the
Holder's receipt of the Notice of Major Transaction.

     D. [Intentionally Deleted].

     E. Purchase Rights. If at any time after the First Closing,  subject to the
limitations  contained herein, the Company issues any Convertible  Securities or
rights  to  purchase  stock,   warrants,   securities  or  other  property  (the
"Distributed  Items")  pro rata to the  record  holders  of any  class of Common
Stock,  then the Holders will be entitled to acquire,  upon the terms applicable
to such  Distributed  Items, the aggregate  Distributed  Items which such Holder
could have acquired if such Holder had held the number of shares of Common Stock
acquirable  upon complete  conversion of the Preferred  Stock (without regard to
any  limitations  on  conversion  or  exercise  herein or  elsewhere  contained)
immediately  before the date on which a record is taken for the grant,  issuance
or sale of such  Distributed  Items, or, if no such record is taken, the date as
of which the record  holders of Common Stock are to be determined for the grant,
issue or sale of such Distributed Items.

     F.  Notice  of  Adjustments.  Upon the  occurrence  of each  adjustment  or
readjustment  pursuant to this  Article XI, the Company,  at its expense,  shall
promptly compute such adjustment or readjustment and prepare and furnish to each
Holder a certificate  setting forth such adjustment or readjustment  and showing
in detail the facts upon which such  adjustment or  readjustment  is based.  The
Company shall,  upon the written  request at any time of any Holder,  furnish to
such  Holder  a  like   certificate   setting  forth  (i)  such   adjustment  or
readjustment,  (ii) the  Conversion  Price at the time in  effect  and (iii) the
number of shares of Common Stock and the amount,  if any, of other securities or
property  which at the time  would be  received  upon  conversion  of a share of
Preferred Stock.

                               XII. VOTING RIGHTS

     The  holders of  Preferred  Stock  shall have no voting  power  whatsoever,
except as otherwise provided by applicable law.

     Notwithstanding the above, the Company shall provide each Holder with prior
notification of any meeting of the  stockholders  (and copies of proxy materials
and all other information sent to  stockholders).  If the Company takes a record
of its stockholders for the purpose of determining  stockholders entitled to (a)
receive  payment of any dividend or other  distribution,  any right to subscribe
for, purchase or otherwise acquire (including by way of merger, consolidation or
recapitalization) any share of any class or any other securities or property, or
to receive any other right, or (b) to vote in connection with any proposed sale,
lease or conveyance of all or substantially all of the assets of the Company, or
any proposed merger,  consolidation,  liquidation,  dissolution or winding up of
the Company,  the Company  shall mail a notice to each  Holder,  at least twenty
(20) days prior to the record date specified  therein (or thirty (30) days prior
to the consummation of the transaction or event, whichever is earlier, but in no
event earlier than public announcement of such

                                      -18-

<PAGE>



proposed  transaction),  of the date on which any such record is to be taken for
the purpose of such vote,  dividend,  distribution,  right or other event, and a
brief  statement  regarding  the amount and  character  of such vote,  dividend,
distribution, right or other event to the extent known at such time.

     To the extent  that  under  applicable  law the vote of the  holders of the
Preferred  Stock,  voting  separately as a class or series,  as  applicable,  is
required to  authorize a given action of the Company,  the  affirmative  vote or
consent of the  Holders of at least a  majority  of the shares of the  Preferred
Stock  represented  at a duly held  meeting  at which a quorum is  present or by
written consent of the Majority  Holders (except as otherwise may be required by
applicable law shall constitute the approval of such action by the class. To the
extent that under  applicable  law Holders are entitled to vote on a matter with
holders of Common Stock,  voting together as one class,  each share of Preferred
Stock  shall be  entitled  to a number of votes equal to the number of shares of
Common  Stock  into  which it is then  convertible  at the  lower  of the  Fixed
Conversion Price or the Variable Conversion Price then in effect (without giving
effect to any  limitation on conversion  with respect  thereto) using the record
date for the  taking  of such vote of  stockholders  as the date as of which the
Conversion Price is calculated.


                           XIII. PROTECTION PROVISIONS

     The Company shall not, without first obtaining the approval of the Majority
Holders  and, to the extent their  interests  may be  adversely  affected,  each
initial Holder of Preferred Stock: a. alter or change the rights, preferences or
privileges of the Preferred Stock; b. alter or change the rights, preferences or
privileges  of any capital  stock of the Company so as to affect  adversely  the
Preferred  Stock;  c. create any Senior  Securities;  d. increase the authorized
number of shares of  Preferred  Stock;  e.  redeem  (other than shares of Common
Stock, or options or rights to acquire Common Stock, purchased from employees or
directors of the Company  pursuant to any stock option or other equity incentive
plan adopted by the Company prior to the date of the First Closing or adopted by
the Company in the good faith business  judgment of the Board of Directors after
the  date of the  First  Closing),  or  declare  or pay  any  cash  dividend  or
distribution  on,  any  Junior  Securities;  or  (g) do any  act  or  thing  not
authorized or  contemplated  by this  Certificate  of  Designations  which would
result in any taxation with respect to the Preferred  Stock under Section 305 of
the Internal  Revenue Code of 1986, as amended,  or any comparable  provision of
the Internal  Revenue Code as hereafter  from time to time amended (or otherwise
suffer to exist any such taxation as a result thereof).

                               XIV. MISCELLANEOUS

     A.  Cancellation  of Preferred  Stock. If any shares of Preferred Stock are
converted  pursuant to Article IV, the shares so  converted  shall be  canceled,
shall  return to the status of  authorized  but unissued  preferred  stock of no
designated series, and shall not be issuable by the Company as Preferred Stock.


                                      -19-

<PAGE>



     B. Lost or Stolen Certificates. Upon receipt by the Company of (i) evidence
of  the  loss,   theft,   destruction  or  mutilation  of  any  Preferred  Stock
Certificate(s)  and  (ii) (y) in the case of  loss,  theft  or  destruction,  of
indemnity (or bond, in cases in which the Holder actually  received the original
or replacement certificate for such Preferred Stock from the Company) reasonably
satisfactory  to the Company,  or (z) in the case of mutilation,  upon surrender
and  cancellation  of the  Preferred  Stock  Certificate(s),  the Company  shall
execute and deliver new Preferred Stock  Certificate(s)  of like tenor and date.
However,  the  Company  shall not be  obligated  to reissue  such lost or stolen
Preferred  Stock  Certificate(s)  if the Holder  contemporaneously  requests the
Company to convert such Preferred Stock.

     C. Allocation of Cap Amount and Reserved Amount. The initial Cap Amount and
Reserved  Amount shall be allocated to the Holders in the same proportion as the
number of shares of Preferred  Stock held by such Holder bears to the  aggregate
number of outstanding shares of Preferred Stock. Each increase to the Cap Amount
or Reserved  Amount shall be allocated  pro rata among the Holders  based on the
number of  shares  of  Preferred  Stock  held by each  Holder at the time of the
increase in the Cap Amount or Reserved Amount,  as the case may be. In the event
a Holder  shall  sell or  otherwise  transfer  any of such  Holder's  shares  of
Preferred  Stock,  each transferee shall be allocated a pro rata portion of such
transferor's  Cap Amount and Reserved  Amount.  Any portion of the Cap Amount or
Reserved  Amount which remains  allocated to any person or entity which does not
hold any Preferred Stock shall be allocated to the remaining  Holders,  pro rata
based on the number of shares of Preferred  Stock then held by such Holders.  In
the event the application of the Cap Amount or the Reserved Amount would prevent
the conversion of a portion of the Preferred  Stock or the exercise of a portion
of the  Warrants,  each  Holder  may  determine  in  the  sole  exercise  of its
discretion,  subject  to the  provisions  of this  Certificate  of  Designation,
whether and in what amounts  Preferred Stock will be converted or whether and in
what amounts Warrants will be exercised.

     D. Statements of Available Shares. Upon request,  the Company shall deliver
to each Holder a written report  notifying the Holders of any  occurrence  which
prohibits the Company from issuing  Common Stock upon any such  conversion.  The
report  shall also  specify (i) the total  number of shares of  Preferred  Stock
outstanding  as of the date of the  request,  (ii) the total number of shares of
Common Stock issued upon all  conversions of Preferred Stock through the date of
the request, (iii) the total number of shares of Common Stock which are reserved
for  issuance  upon  conversion  of the  Preferred  Stock  as of the date of the
request,  and (iv) the  total  number  of  shares  of  Common  Stock  which  may
thereafter  be issued by the Company  upon  conversion  of the  Preferred  Stock
before the Company would exceed the Cap Amount and Reserved Amount.  The Company
shall,  within five (5) days after delivery to the Company of a written  request
by any Holder, provide all of the information enumerated in clauses (i) - (v) of
this Section XIV.D and make public disclosure  thereof if such information would
constitute material nonpublic information.

     E. Payment of Cash; Defaults.  Whenever the Company is required to make any
cash payment to a Holder under this  Certificate of Designation (as a Conversion
Default  Payment,  Redemption  Amount or otherwise),  such cash payment shall be
made to the  Holder by the  method ( by  certified  or  cashier's  check or wire
transfer of immediately available funds) elected by such Holder. If such payment
is not  delivered  when due (any such  amount not paid when due being a "Default
Amount")  such  Holder  shall  thereafter  be entitled to interest on the unpaid
amount at a per

                                      -20-

<PAGE>



annum  rate  equal to the  lower of  twenty-four  percent  (24%) or the  highest
interest rate  permitted by applicable  law until such amount is paid in full to
the Holder. In addition, and notwithstanding  anything to the contrary contained
in this Certificate, a Holder may elect in writing to convert all or any portion
of accrued Default Amounts, at any time and from time to time, into Common Stock
at the lowest Conversion Price in effect during the period beginning on the date
of the default with respect thereto  through the cure date for such default.  In
the event that a Holder  elects to  convert  all or any  portion of the  Default
Amounts into Common Stock, the Holder shall so notify the Company on a Notice of
Conversion of such portion of the Default Amounts which such Holder elects to so
convert and such  conversion  shall otherwise be effected in accordance with the
provisions of, and subject to limitations contained in, Article IV.

     F. Status as  Stockholder.  Upon  submission of a Notice of Conversion by a
Holder of Preferred  Stock, the shares covered thereby shall be deemed converted
into  shares  of  Common  Stock  and the  Holder's  rights  as a Holder  of such
converted  shares of Preferred  Stock shall cease and terminate,  excepting only
the right to receive  certificates  for such  shares of Common  Stock and to any
remedies  provided  herein or  otherwise  available  at law or in equity to such
Holder  because  of a failure by the  Company  to comply  with the terms of this
Certificate of Designation.  Notwithstanding the foregoing,  if a Holder has not
received  certificates  for all  shares of Common  Stock on or before  the tenth
(10th)  business day after the expiration of the Extended  Delivery  Period with
respect to a  conversion  of  Preferred  Stock for any reason,  then (unless the
Holder  otherwise  elects to retain its status as a holder of Common  Stock) the
Holder shall  regain the rights of a holder of  Preferred  Stock with respect to
such  unconverted  shares of Preferred  Stock and the Company shall,  as soon as
practicable,  return such  unconverted  shares to the Holder.  In all cases, the
Holder  shall  retain the right to elect  between or among any of its rights and
remedies  (including,  without  limitation,  (i) the right to receive Conversion
Default  Payments  pursuant to Section VII.A to the extent required  thereby for
such Conversion Default and any subsequent Conversion Default and (ii) the right
with respect to  conversions  in accordance  with Section  XIV.E,  to the extent
applicable) for the Company's failure to convert Preferred Stock.

     G. Remedies, Characterizations,  Other Obligations, Breaches and Injunctive
Relief.  The  remedies  provided in this  Certificate  of  Designation  shall be
cumulative  and  in  addition  to  all  other  remedies   available  under  this
Certificate of Designation,  at law or in equity (including a decree of specific
performance and/or other injunctive relief), no remedy contained herein shall be
deemed a waiver of compliance with the provisions giving rise to such remedy and
nothing herein shall limit a Holder's right to actual damages for any failure by
the  Company  to  comply  with the  terms  of this  Certificate  of  Designation
(including,  without limitation, damages incurred to effect "cover" of shares of
Common Stock  anticipated  to be received  upon a conversion  hereunder  but not
received in accordance with the terms hereof);  provided,  however,  that in the
event  that an action is brought  by a Holder or by the  Company  in  connection
herewith  the  non-prevailing  party  shall  pay the costs  (including,  without
limitation,  reasonable  attorney's  fees and  expenses)  incurred  by the other
party(ies) to such action. The Company covenants to each Holder that there shall
be no  characterization  concerning  this  instrument  other  than as  expressly
provided  herein.  Amounts  set forth or  provided  for herein  with  respect to
payments,  conversion  and the like (and the  computation  thereof) shall be the
amounts to be received by the Holder  hereof and shall not,  except as expressly
provided  herein,  be subject to any other  obligation  of the  Company  (or the
performance  thereof).  The  Company  acknowledges  that a  breach  by it of its
obligations hereunder will cause irreparable

                                      -21-

<PAGE>



harm to the holders of  Preferred  Stock and that the remedy at law for any such
breach may he inadequate. The Company therefore agrees that, in the event of any
such breach or threatened breach, the Holders shall be entitled,  in addition to
all other available remedies, to an injunction  restraining any breach,  without
the necessity of showing  economic  loss and without any bond or other  security
being required.

     H. Specific Shall Not Limit General;  Construction.  No specific  provision
contained  in this  Certificate  of  Designation  shall limit or modify any more
general  provision  contained  herein.  This Certificate of Designation shall be
deemed to be jointly  drafted by the Company and all Purchasers and shall not be
construed against any person as the drafter hereof.

     I. Failure or Indulgence  Not Waiver.  Except as otherwise  explicitly  set
forth in this  Certificate of Designation,  no failure or delay on the part of a
Holder in the exercise of any power, right or privilege  hereunder shall operate
as a waiver thereof, not shall any single or partial exercise of any such power,
right or privilege  preclude other or further  exercise  thereof or of any other
right, power or privilege.


                                      -22-

<PAGE>



                                   Schedule 1

                              NOTICE OF CONVERSION

To:      Pharmos Corporation
         33 Wood Avenue South
         Iselin, New Jersey 08330
         Telecopy: [(732) 603-3526]
         Attn: Chief Financial Officer

The undersigned  hereby  irrevocably  elects to convert _____ shares of Series C
Preferred Stock (the  "Conversion"),  represented by stock  certificate  Nos(s).
____________ (the "Preferred Stock Certificates") into ordinary shares of common
stock ("Common Stock") of Pharmos  Corporation (the "Company")  according to the
terms and conditions of the Certificate of Designations,  Preferences and Rights
of Series C  Convertible  Participating  Preferred  Stock (the  "Certificate  of
Designation"),  as of the date written below.  If securities are to be issued in
the name of a person other than the  undersigned,  the undersigned  will pay all
transfer  taxes  payable  with  respect  thereto.  No fee will be charged to the
holder for any  conversion,  except for transfer  taxes,  if any. A copy of each
Preferred Stock  Certificate is attached  hereto (or evidence of loss,  theft or
destruction thereof).

The  undersigned  represents  and  warrants  that all  offers  and  sales by the
undersigned of the securities issuable to the undersigned upon conversion of the
Series C Convertible Participating Preferred Stock shall be made pursuant to the
registration  of the Common Stock under the  Securities  Act of 1933, as amended
(the "Act"), or pursuant to an exemption from registration under the Act.

The following paragraphs are only effective if the applicable box is checked:

|_|  The undersigned  hereby requests that the Company  electronically  transmit
     the Common  Stock  issuable  pursuant to this Notice of  Conversion  to the
     account of the undersigned's Prime Broker (which is  _______________)  with
     DTC through its Deposit Withdrawal Agent Commission System.

|_|  The undersigned hereby requests foreign delivery of the Common Stock to the
     address indicated below.

                              Date of Conversion:  _____________________________

                              Applicable Conversion Price: _____________________

                              Amount of Accrued and Unpaid
                              Premium on the Face Amount to
                              be converted, if any: ____________________________




                              Amount of Conversion Default
                              Payments to be Converted, if any: ________________


<PAGE>




                              Number of Shares of
                              Common Stock to be Issued: _______________________


                              Signature: _______________________________________

                              Name: ____________________________________________

                              Adress: __________________________________________

Ehrenreich, Eilenberg, Krause & Zivian, LLP
11 East 44th Street
17th Floor
New York, NY 10017
Attention: Adam Eilenberg, Esq.
Facsimile No.: (212) 986-2399











<PAGE>



                                                                       EXHIBIT B



VOID AFTER 5:00 P.M. NEW YORK, NEW YORK
TIME ON February 4, 2003


THE SECURITIES  REPRESENTED BY THIS  CERTIFICATE  HAVE NOT BEEN REGISTERED UNDER
THE SECURITIES ACT OF 1933, AS AMENDED,  OR THE SECURITIES  LAWS OF ANY STATE OF
THE UNITED STATES. THE SECURITIES  REPRESENTED HEREBY MAY NOT BE OFFERED OR SOLD
OR OTHERWISE TRANSFERRED IN THE ABSENCE OF AN EFFECTIVE  REGISTRATION  STATEMENT
FOR THE SECURITIES UNDER APPLICABLE  SECURITIES LAWS, OR UNLESS OFFERED, SOLD OR
TRANSFERRED   PURSUANT  TO  AN  AVAILABLE   EXEMPTION   FROM  THE   REGISTRATION
REQUIREMENTS OF THOSE LAWS.

                                             Right to Purchase 500,000 Shares of
                                          Common Stock, par value $.03 per share

Date: February 4, 1998


                               PHARMOS CORPORATION
                             STOCK PURCHASE WARRANT


     THIS CERTIFIES THAT, for value received,  the undersigned or its registered
assigns (each a "Holder"),  is entitled to purchase from Pharmos Corporation,  a
Nevada corporation (the "Company"),  at any time or from time to time during the
period  specified  in Section 2 hereof,  500,000  fully  paid and  nonassessable
shares of the  Company's  common  stock,  par value $.03 per share (the  "Common
Stock"),  at an exercise price of $2.67 per share (the "Exercise  Price").  This
Warrant is being issued pursuant to that certain  Securities  Purchase Agreement
dated as of February 4, 1998  between  the Company and the  signatories  thereto
(the  "Securities  Purchase  Agreement").  The number of shares of Common  Stock
purchasable  hereunder (the "Warrant Shares") and the Exercise Price are subject
to adjustment as provided in Section 4 hereof.  The term  "Warrants"  means this
Warrant and the other  warrants of the Company  issued  pursuant to the terms of
the Securities Purchase Agreement.

     The term  "Closing Bid Price" means,  for any security as of any date,  the
closing  bid price of such  security  on the  principal  securities  exchange or
trading  market where such security is listed or traded as reported by Bloomberg
Financial  Markets or a  comparable  reporting  service of  national  reputation
selected  by the  Company  and  reasonably  acceptable  to Holder  if  Bloomberg
Financial  Markets is not then  reporting  closing  bid prices of such  security
(collectively,  "Bloomberg"),  or if the  foregoing  does  not  apply,  the last
reported  sale  price of such  security  in the  over-the-counter  market or the
electronic  bulletin board of such security as reported by Bloomberg,  or, if no
sale price is reported for such  security by  Bloomberg,  the average of the bid
prices of any market  makers for such  security as reported in the "pink sheets"
by the National Quotation Bureau, Inc. If the Closing


<PAGE>



Bid Price  cannot be  calculated  for such  security  on such date on any of the
foregoing  bases,  the Closing Bid Price of such  security on such date shall be
the fair market value as reasonably  determined  by an  investment  banking firm
selected by the Company and  reasonably  acceptable to the Holder with the costs
of such appraisal to be borne by the Company.

     This Warrant is subject to the following terms, provisions, and conditions:

I. Mechanics of Exercise.  Subject to the provisions hereof, including,  without
limitation,  the limitations  contained in Section 8(f) hereof, this Warrant may
be exercised as follows:

     A. Manner of Exercise.  This  Warrant may be  exercised  by the Holder,  in
whole or in part, by the surrender of this Warrant (or evidence of loss,  theft,
destruction  or  mutilation  thereof in  accordance  with Section 8(c)  hereof),
together with a completed  exercise  agreement in the Form of Exercise Agreement
attached hereto as Exhibit 1 (the "Exercise  Agreement"),  to the Company at the
Company's  principal  executive  offices (or such other  office or agency of the
Company as it may  designate by notice to the  Holder),  and upon (i) payment to
the Company in cash, by certified or official bank check or by wire transfer for
the  account  of the  Company,  of the  Exercise  Price for the  Warrant  Shares
specified  in the Exercise  Agreement  or (ii) if the Holder  elects to effect a
Cashless  Exercise (as defined in Section 12(c) below),  delivery to the Company
of a written notice of an election to effect a Cashless Exercise for the Warrant
Shares  specified in the  Exercise  Agreement.  The Warrant  Shares so purchased
shall be deemed to be issued to the Holder or Holder's designees,  as the record
owner of such  shares,  as of the date on which  this  Warrant  shall  have been
surrendered,  the completed  Exercise  Agreement shall have been delivered,  and
payment (or notice of an election to effect a Cashless Exercise) shall have been
made for such shares as set forth above.

     B. Issuance of Certificates.  Subject to Section 1(c), certificates for the
Warrant  Shares  so  purchased,  representing  the  aggregate  number  of shares
specified in the Exercise  Agreement,  shall be delivered to the Holder within a
reasonable  time, not exceeding four (4) business days, after this Warrant shall
have been so exercised (the "Delivery  Period").  The  certificates so delivered
shall be in such  denominations  as may be  requested by the Holder and shall be
registered  in the name of Holder or such other name as shall be  designated  by
such  Holder.  If this Warrant  shall have been  exercised  only in part,  then,
unless this Warrant has expired,  the Company shall, at its expense, at the time
of  delivery  of  such  certificates,  deliver  to  the  Holder  a  new  Warrant
representing  the number of shares with respect to which this Warrant  shall not
then have been exercised.

     C.  Exercise  Disputes.  In the  case of any  dispute  with  respect  to an
exercise, the Company shall promptly issue such number of shares of Common Stock
as are not disputed in accordance  with this Section.  If such dispute  involves
the  calculation  of the Exercise  Price,  the Company shall submit the disputed
calculations to an independent accounting firm of national standing,  reasonably
acceptable to the Holder and the Company via facsimile within three (3) business
days of receipt of the Exercise  Agreement.  The accounting firm shall audit the
calculations and notify the Company and the converting  Holder of the results no
later  than  two (2)  business  days  from  the date it  receives  the  disputed
calculations.  The accounting  firm's  calculation  shall be deemed  conclusive,
absent  manifest error.  The Company shall then issue the appropriate  number of
shares of Common Stock in accordance with this Section.


                                       -2-

<PAGE>



     D. Fractional Shares. No fractional shares of Common Stock are to be issued
upon the exercise of this Warrant,  but the Company shall pay a cash  adjustment
in respect of any  fractional  share  which  would  otherwise  be issuable in an
amount  equal to the same  fraction of the  Exercise  Price of a share of Common
Stock;  provided  that in the  event  that  sufficient  funds  are  not  legally
available  for the  payment of such cash  adjustment  any  fractional  shares of
Common Stock shall be rounded up to the next whole number.

     E. Buy-In.  If (i) the Company  fails for any reason to deliver  during the
Delivery  Period  shares of  Common  Stock to Holder  upon an  exercise  of this
Warrant and (ii) after the  applicable  Delivery  Period with respect to such an
exercise,  Holder purchases (in an open market  transaction or otherwise) shares
of Common Stock to make  delivery  upon a sale by Holder of the shares of Common
Stock  (the  "Sold  Shares")  which  Holder was  entitled  to receive  upon such
exercise (a  "Buy-in"),  the Company  shall pay Holder (in addition to any other
remedies  available to Holder) the amount by which (x) Holder's  total  purchase
price (including brokerage commission, if any) for the shares of Common Stock so
purchased  exceeds  (y) the  lesser  of (A) the  Exercise  Price  or (B) the net
proceeds  received  by Holder  from the sale of the Sold  Shares.  Holder  shall
provide the  Company  written  notification  indicating  any amounts  payable to
Holder pursuant to this subsection.

II. Period of Exercise. This Warrant is exercisable at any time or from time to
time on or after the first (1st) anniversary of the date hereof and before 5:00
P.M., New York, New York time on the fifth (5th) anniversary of the date hereof
(the "Exercise Period").

III. Certain Agreements of the Company.  The Company hereby covenants and agrees
as follows:

     A.  Shares to be Fully Paid.  All Warrant  Shares  will,  upon  issuance in
accordance with the terms of this Warrant,  be validly  issued,  fully paid, and
non-assessable and free from all taxes, liens, claims and encumbrances.

     B. Reservation of Shares.  During the Exercise Period, the Company shall at
all times  have  authorized,  and  reserved  for the  purpose of  issuance  upon
exercise  of this  Warrant,  a  sufficient  number of shares of Common  Stock to
provide for the exercise of this Warrant.

     C. Listing.  The Company shall promptly secure the listing of the shares of
Common Stock  issuable  upon  exercise of this Warrant upon the Nasdaq  National
Market System,  the Nasdaq SmallCap  Market,  the New York Stock Exchange or the
American Stock  Exchange as required by Section 4.9 of the  Securities  Purchase
Agreement  and upon each  national  securities  exchange or automated  quotation
system,  if any,  upon which  shares of Common  Stock are then  listed or become
listed and shall maintain,  so long as any other shares of Common Stock shall be
so listed, such listing of all shares of Common Stock from time to time issuable
upon  the  exercise  of this  Warrant;  and the  Company  shall  so list on each
national  securities exchange or automated quotation system, as the case may be,
and shall  maintain  such  listing of any other  shares of capital  stock of the
Company  issuable upon the exercise of this Warrant so long as any shares of the
same class shall be listed on such  national  securities  exchange or  automated
quotation system.

     D. Certain  Actions  Prohibited.  The Company will not, by amendment of its
charter or  through  any  reorganization,  transfer  of  assets,  consolidation,
merger, dissolution, issue or sale of

                                       -3-

<PAGE>



securities, or any other voluntary action, avoid or seek to avoid the observance
or  performance of any of the terms to be observed or performed by it hereunder,
but will at all  times  in good  faith  assist  in the  carrying  out of all the
provisions  of  this  Warrant  and in the  taking  of all  such  actions  as may
reasonably  be  requested  by the Holder of this Warrant in order to protect the
exercise privilege of the Holder of this Warrant,  consistent with the tenor and
purpose of this Warrant.  Without limiting the generality of the foregoing,  the
Company  (i) will not  increase  the par value of any  shares  of  Common  Stock
receivable  upon the exercise of this Warrant  above the Exercise  Price then in
effect,  and (ii) will take all such actions as may be necessary or  appropriate
in  order  that the  Company  may  validly  and  legally  issue  fully  paid and
nonassessable shares of Common Stock upon the exercise of this Warrant.

IV. Antidilution Provisions.  During the Exercise Period, the Exercise Price and
the number of Warrant Shares shall be subject to adjustment from time to time as
provided in this  Section 4. In the event that any  adjustment  of the  Exercise
Price as required  herein  results in a fraction of a cent,  such Exercise Price
shall be rounded up or down to the nearest cent.

     A.  Adjustment  of  Exercise  Price and Number of Shares  upon  Issuance of
Common Stock.  Except as otherwise  provided in Section 4(c) and 4(e) hereof, if
and whenever after the initial  issuance of this Warrant,  the Company issues or
sells,  or in  accordance  with  Section 4(b) hereof is deemed to have issued or
sold, any shares of Common Stock for no consideration or for a consideration per
share less than the Exercise  Price as in effect on the date of issuance of such
shares of Common Stock (a "Dilutive Issuance"),  then effective immediately upon
the Dilutive  Issuance,  the Exercise Price will be adjusted in accordance  with
the following formula:

                  E' = (E) (O + P/E) / (CSDO)


                  where:

                  E'       =        the adjusted Exercise Price
                  E        =        the then current Exercise Price;
                  O        =        the number of shares of Common Stock 
                                    outstanding immediately
                                    prior to the Dilutive Issuance;
                  P        =        the aggregate consideration, calculated as
                                    set forth in Section 4(b) hereof, received
                                    by the Company upon such Dilutive Issuance;
                                    and
                  CSDO     =        the total number of shares of
                                    Common Stock Deemed Outstanding (as
                                    herein defined) immediately after
                                    the Dilutive Issuance.

     B. Effect on Exercise Price of Certain Events.  For purposes of determining
the adjusted  Exercise  Price under Section 4(a) hereof,  the following  will be
applicable:

     1.  Issuance of Rights or Options.  If the Company in any manner  issues or
grants any warrants,  rights or options, whether or not immediately exercisable,
to subscribe for or to purchase  Common Stock or other  securities  exercisable,
convertible  into or exchangeable for Common Stock  ("Convertible  Securities"),
but not to  include  the grant or  exercise  of any shares of Common  Stock,  or
options or rights to acquire Common Stock, which may hereafter be granted or

                                       -4-

<PAGE>



exercised  under any  employee  or  Director  benefit  plan of the  Company  now
existing or to be  implemented  in the future,  so long as the  issuance of such
stock,  options or rights is approved by a majority of the non-employee  members
of the Board of  Directors  of the  Company  or a majority  of the  members of a
committee of non-employee directors established for such purpose (such warrants,
rights and  options to  purchase  Common  Stock or  Convertible  Securities  are
hereinafter referred to as "Options"),  and the price per share for which Common
Stock is issuable  upon the  exercise of such  Options is less than the Exercise
Price as in effect on the date of issuance  ("Below Market  Options"),  then the
maximum total number of shares of Common Stock issuable upon the exercise of all
such Below Market Options  (assuming  full  exercise,  conversion or exchange of
Convertible  Securities,  if applicable) will, as of the date of the issuance of
such Below Market  Options,  be deemed to be outstanding and to have been issued
and sold by the Company for the price per share  provided  for  pursuant to such
Below Market Option. For purposes of the preceding sentence, the price per share
for which  Common  Stock is  issuable  upon the  exercise  of such Below  Market
Options is  determined  by dividing (i) the total  amount,  if any,  received or
receivable by the Company as consideration  for the issuance or granting of such
Below  Market  Options,   plus  the  minimum   aggregate  amount  of  additional
consideration,  if any,  payable to the  Company  upon the  exercise of all such
Below Market Options,  plus, in the case of Convertible Securities issuable upon
the  exercise of such Below  Market  Options,  the minimum  aggregate  amount of
additional  consideration  payable  upon the  exercise,  conversion  or exchange
thereof  at the time  such  Convertible  Securities  first  become  exercisable,
convertible  or  exchangeable,  by (ii) the  maximum  total  number of shares of
Common  Stock  issuable  upon the  exercise  of all such  Below  Market  Options
(assuming full conversion of Convertible Securities,  if applicable) on the date
of issuance of such Below Market Options.  No further adjustment to the Exercise
Price  will be made upon the  actual  issuance  of such  Common  Stock  upon the
exercise  of such Below  Market  Options  or upon the  exercise,  conversion  or
exchange of Convertible  Securities  issuable upon exercise of such Below Market
Options.

     (2) Issuance of Convertible Securities.

     (i)  If  the  Company  in  any  manner  issues  or  sells  any  Convertible
Securities,  whether or not immediately  convertible  (other than where the same
are  issuable  upon the  exercise of Options)  and the price per share for which
Common  Stock is  issuable  upon  such  exercise,  conversion  or  exchange  (as
determined  pursuant  to Section  4(b)(ii)(B)  if  applicable)  is less than the
Exercise  Price as in effect on the date of  issuance,  then the  maximum  total
number of shares of Common  Stock  issuable  upon the  exercise,  conversion  or
exchange of all such Convertible Securities will, as of the date of the issuance
of such  Convertible  Securities,  be deemed to be outstanding  and to have been
issued  and  sold by the  Company  for the  price  per  share  pursuant  to such
Convertible Security.  For the purposes of the preceding sentence, the price per
share for which  Common  Stock is issuable  upon such  exercise,  conversion  or
exchange is  determined by dividing (i) the total  amount,  if any,  received or
receivable by the Company as consideration  for the issuance or sale of all such
Convertible  Securities,   plus  the  minimum  aggregate  amount  of  additional
consideration,  if any, payable to the Company upon the exercise,  conversion or
exchange  thereof  at  the  time  such   Convertible   Securities  first  become
exercisable,  convertible or  exchangeable,  by (ii) the maximum total number of
shares of Common Stock issuable upon the exercise, conversion or exchange of all
such Convertible Securities. No further adjustment to the Exercise Price will be
made upon the actual issuances of such Common Stock upon exercise, conversion or
exchange of such Convertible Securities.


                                       -5-

<PAGE>



     (ii)  If  the  Company  in any  manner  issues  or  sells  any  Convertible
Securities with a fluctuating  conversion or exercise price or exchange ratio (a
"Variable Rate Convertible Security"), then the price per share for which Common
Stock is issuable upon such exercise, conversion or exchange for purposes of the
calculation contemplated by Section 4(b)(ii)(A) shall be deemed to be the lowest
price per share which would be applicable  assuming that (1) all holding  period
and other  conditions to any discounts  contained in such  Convertible  Security
have been  satisfied,  and (2) the Market  Price on the date of issuance of such
Convertible  Security  was 80% of the  Market  Price on such date (the  "Assumed
Variable Market Price").

     (3)  Change in Option  Price or  Conversion  Rate.  Except for the grant or
exercise of any stock or options  which may  hereafter  be granted or  exercised
under any employee or Director benefit plan of the Company now existing or to be
implemented  in the future,  so long as the issuance of such stock or options is
approved by a majority of the non-employee  members of the Board of Directors of
the  Company  or a  majority  of the  members  of a  committee  of  non-employee
directors  established for such purpose, if there is a change at any time in (i)
the amount of additional  consideration payable to the Company upon the exercise
of any Options; (ii) the amount of additional consideration,  if any, payable to
the  Company  upon the  exercise,  conversion  or  exchange  or any  Convertible
Securities;   or  (iii)  the  rate  at  which  any  Convertible  Securities  are
convertible into or exchangeable for Common Stock (other than under or by reason
of  provisions  designed to protect  against  dilution),  the Exercise  Price in
effect at the time of such change will be readjusted to the Exercise Price which
would  have  been in  effect  at such  time  had  such  Options  or  Convertible
Securities still outstanding provided for such changed additional  consideration
or changed  conversion rate, as the case may be, at the time initially  granted,
issued or sold.

     (4) Treatment of Expired  Options and Unexercised  Convertible  Securities.
If, in any case,  the total  number  of  shares of Common  Stock  issuable  upon
exercise  of any  Options  or  upon  exercise,  conversion  or  exchange  of any
Convertible  Securities is not, in fact,  issued and the rights to exercise such
option or to exercise,  convert or exchange such  Convertible  Securities  shall
have expired or terminated, the Exercise Price then in effect will be readjusted
to the  Exercise  Price  which  would  have  been in  effect at the time of such
expiration or  termination  had such Options or Convertible  Securities,  to the
extent  outstanding  immediately prior to such expiration or termination  (other
than in respect  of the  actual  number of shares of Common  Stock  issued  upon
exercise or conversion thereof), never been issued.

     (5) Calculation of Consideration  Received. If any Common Stock, Options or
Convertible  Securities are issued,  granted or sold for cash, the consideration
received  therefor for  purposes of this Warrant will be the amount  received by
the Company therefor,  before deduction of reasonable commissions,  underwriting
discounts or  allowances  or other  reasonable  expenses paid or incurred by the
Company in  connection  with such  issuance,  grant or sale.  In case any Common
Stock, Options or Convertible  Securities are issued or sold for a consideration
part or all of which shall be other than cash,  the amount of the  consideration
other than cash  received by the Company  will be the fair market  value of such
consideration  except  where such  consideration  consists  of  freely-tradeable
securities,  in which case the amount of  consideration  received by the Company
will be the Market Price  thereof as of the date of receipt.  In case any Common
Stock,  Options or  Convertible  Securities  are issued in  connection  with any
merger or consolidation in which the Company is the surviving  corporation,  the
amount of consideration therefor will be deemed to be

                                       -6-

<PAGE>



the fair  market  value of such  portion of the net assets and  business  of the
non-surviving  corporation as is attributable  to such Common Stock,  Options or
Convertible  Securities,  as the  case  may be.  The  fair  market  value of any
consideration other than cash or securities will be determined in the good faith
reasonable business judgment of the Board of Directors.

     (6)  Exceptions  to  Adjustment  of Exercise  Price.  No  adjustment to the
Exercise  Price will be made (i) upon the exercise of any  warrants,  options or
convertible  securities  issued and outstanding on the date hereof in accordance
with the  terms of such  securities  as of such  date;  (ii)  upon the  grant or
exercise of any shares of Common Stock,  or options or rights to acquire  Common
Stock,  which may  hereafter  be  granted or  exercised  under any  employee  or
Director  benefit plan of the Company now existing or to be  implemented  in the
future, so long as the issuance of such stock,  options or rights is approved by
a majority of the non-employee  members of the Board of Directors of the Company
or  a  majority  of  the  members  of  a  committee  of  non-employee  directors
established  for such purpose;  (iii) upon the issuance of the Common Shares (as
defined in the  Securities  Purchase  Agreement) or Warrants in accordance  with
terms of the  Securities  Purchase  Agreement;  or (iv) upon the exercise of the
Warrants.

     C. Subdivision or Combination of Common Stock. If the Company,  at any time
after the initial  issuance of this  Warrant,  subdivides  (by any stock  split,
stock dividend, recapitalization, reorganization, reclassification or otherwise)
its shares of Common Stock into a greater number of shares, then, after the date
of  record  for  effecting  such  subdivision,  the  Exercise  Price  in  effect
immediately prior to such subdivision will be  proportionately  reduced.  If the
Company,  at any time after the initial  issuance of this Warrant,  combines (by
reverse  stock  split,  recapitalization,  reorganization,  reclassification  or
otherwise)  its shares of Common  Stock into a smaller  number of shares,  then,
after the date of record for effecting such  combination,  the Exercise Price in
effect immediately prior to such combination will be proportionately increased.

     D.  Adjustment  in Number of Shares.  Upon each  adjustment of the Exercise
Price  pursuant  to the  provisions  of this  Section 4, the number of shares of
Common  Stock  issuable  upon  exercise  of this  Warrant  shall be  adjusted by
multiplying a number equal to the Exercise Price in effect  immediately prior to
such  adjustment by the number of shares of Common Stock  issuable upon exercise
of this Warrant immediately prior to such adjustment and dividing the product so
obtained by the adjusted Exercise Price.

     E. Major Transactions.  If the Company shall consolidate with or merge into
any corporation or reclassify its outstanding shares of Common Stock (other than
by way of subdivision or reduction of such shares) (each a "Major Transaction"),
then  each  holder  of  a  Warrant  shall  thereafter  be  entitled  to  receive
consideration,  in  exchange  for such  Warrant,  equal to the  greater  of,  as
determined in the sole discretion of such holder,  a warrant to purchase (at the
same  aggregate  exercise  price  and on the same  terms and  conditions  as the
Warrant  surrendered) the number of shares of stock or securities or property of
the Company,  or of the entity resulting from such  consolidation or merger (the
"Major Transaction Consideration"), to which a holder of the number of shares of
Common Stock  delivered  upon  exercise of such Warrant would have been entitled
upon such Major  Transaction had the holder of such Warrant  exercised  (without
regard to any  limitations  on  exercise  herein  contained)  the Warrant on the
trading date  immediately  preceding the public  announcement of the transaction
resulting in such Major Transaction and had such Common Stock

                                       -7-

<PAGE>



been  issued and  outstanding  and had such  holder been the holder of record of
such Common Stock at the time of such Major  Transaction,  and the Company shall
make  lawful  provision  therefor  as a part of such  consolidation,  merger  or
reclassification.  No sooner  than twenty (20) days nor later than five (5) days
prior to the consummation of the Major Transaction,  but not prior to the public
announcement of such Major Transaction, the Company shall deliver written notice
("Notice of Major  Transaction")  to each holder of  Warrants,  which  Notice of
Major  Transaction  shall be deemed to have been  delivered one (1) business day
following  the  Company's  sending  such notice by telecopy  (provided  that the
Company  sends a  confirming  copy of such  notice on the same day by  overnight
courier) of such Notice of Major  Transaction.  Such Notice of Major Transaction
shall indicate the amount and type of the Major Transaction  Consideration which
such holder would receive under clause (i) of this  paragraph  (e). If the Major
Transaction  Consideration  does not consist entirely of United States currency,
such holder may elect to receive  United  States  currency in an amount equal to
the  value  of  the  Major  Transaction  Consideration  in  lieu  of  the  Major
Transaction  Consideration by delivering  notice of such election to the Company
within five (5) days of the holder's receipt of the Notice of Major Transaction.

     F.  Distribution  of Assets.  In case the Company shall declare or make any
distribution  of its  assets (or  rights to  acquire  its  assets) to holders of
Common Stock as a partial liquidating  dividend,  by way of return of capital or
otherwise (including any dividend or distribution to the Company's  shareholders
of  cash or  shares  (or  rights  to  acquire  shares)  of  capital  stock  of a
subsidiary) (a  "Distribution"),  at any time after the initial issuance of this
Warrant, then the Holder shall be entitled upon exercise of this Warrant for the
purchase of any or all of the shares of Common Stock subject hereto,  to receive
the  amount of such  assets (or  rights)  which  would have been  payable to the
Holder had such  Holder  been the holder of such  shares of Common  Stock on the
record date for the determination of shareholders entitled to such Distribution.

     G. Notices of  Adjustment.  Upon the occurrence of any event which requires
any adjustment of the Exercise  Price,  then, and in each such case, the Company
shall give notice  thereof to the Holder,  which notice shall state the Exercise
Price  resulting from such adjustment and the increase or decrease in the number
of Warrant  Shares  purchasable  at such price upon  exercise,  setting forth in
reasonable  detail  the  method of  calculation  and the facts  upon  which such
calculation is based. Such calculation shall be certified by the chief financial
officer of the Company.

     H. Minimum  Adjustment  of Exercise  Price.  No  adjustment of the Exercise
Price shall be made in an amount of less than 1% of the Exercise Price in effect
at the time such  adjustment  is  otherwise  required  to be made,  but any such
lesser  adjustment  shall be carried  forward  and shall be made at the time and
together  with  the  next  subsequent   adjustment  which,   together  with  any
adjustments  so  carried  forward,  shall  amount  to not  less  than 1% of such
Exercise Price.

     I. Other Notices. In case at any time:

          (a) the Company  shall  declare  any  dividend  upon the Common  Stock
     payable in shares of stock of any class or make any other  distribution  to
     the holders of the Common Stock;

          (b) the Company shall offer for  subscription  pro rata to the holders
     of the Common  Stock any  additional  shares of stock of any class or other
     rights;

                                       -8-

<PAGE>




          (c) there  shall be any  capital  reorganization  of the  Company,  or
     reclassification  of the Common Stock,  or  consolidation  or merger of the
     Company with or into, or sale of all or substantially all of its assets to,
     another corporation or entity; or

          (d) there shall be a voluntary or involuntary dissolution, liquidation
     or  winding-up of the Company;  then, in each such case,  the Company shall
     give to the Holder (a) notice of the date on which the books of the Company
     shall  close or a record  shall be taken for  determining  the  holders  of
     Common  Stock  entitled  to receive  any such  dividend,  distribution,  or
     subscription rights or for determining the holders of Common Stock entitled
     to  vote  in   respect  of  any  such   reorganization,   reclassification,
     consolidation, merger, sale, dissolution, liquidation or winding-up and (b)
     in the case of any such  reorganization,  reclassification,  consolidation,
     merger, sale,  dissolution,  liquidation or winding-up,  notice of the date
     (or, if not then known, a reasonable  approximation thereof by the Company)
     when the same shall take place.  Such notice shall also specify the date on
     which the  holders  of Common  Stock  shall be  entitled  to  receive  such
     dividend,  distribution, or subscription rights or to exchange their Common
     Stock for  stock or other  securities  or  property  deliverable  upon such
     reorganization, reclassification, consolidation, merger, sale, dissolution,
     liquidation,  or winding-up, as the case may be. Such notice shall be given
     at  least  30 days  prior  to the  record  date or the  date on  which  the
     Company's books are closed in respect thereto, but in no event earlier than
     public announcement of such proposed  transaction or event. Failure to give
     any such notice or any defect  therein shall not affect the validity of the
     proceedings referred to in clauses (i), (ii), (iii) and (iv) above.

     J. Certain Definitions.

          (a) "Common Stock Deemed  Outstanding" shall mean the number of shares
     of Common Stock actually  outstanding (not including shares of Common Stock
     held in the treasury of the  Company),  plus (x) in case of any  adjustment
     required by Section 4(a)  resulting  from the issuance of any Options,  the
     maximum  total number of shares of Common Stock  issuable upon the exercise
     of the Options for which the  adjustment is required  (including any Common
     Stock issuable upon the conversion of Convertible  Securities issuable upon
     the  exercise  of  such  Options),  and (y) in the  case of any  adjustment
     required by Section 4(a)  resulting  from the  issuance of any  Convertible
     Securities,  the maximum  total number of shares of Common  Stock  issuable
     upon the exercise, conversion or exchange of the Convertible Securities for
     which  the  adjustment  is  required,  as of the date of  issuance  of such
     Convertible Securities, if any.

          (b)  "Market  Price," as of any date,  (i) means the Closing Bid Price
     for the shares of Common  Stock as  reported to Nasdaq  Small-Cap  National
     Market System for the trading day immediately  preceding such date, or (ii)
     if the Nasdaq Small-Cap National Market System is not the principal trading
     market for the Common Stock, the average of the last reported bid prices on
     the principal  trading  market for the Common Stock during the same period,
     or, if there is no bid price for such period, the last reported sales price
     for such period,  or (iii) if market value cannot be  calculated as of such
     date on any of the foregoing  bases,  the Market Price shall be the average
     fair market value as reasonably  determined  by an investment  banking firm
     selected  by the  Company  and  reasonably  acceptable  to the Holders of a
     majority in interest of the Warrants, with the costs of the appraisal to be
     borne by the  Company.  The manner of  determining  the Market Price of the
     Common

                                       -9-

<PAGE>



     Stock set forth in the foregoing definition shall apply with respect to any
     other security in respect of which a determination  as to market value must
     be made under this Section 4.

          (c) "Common  Stock,"  for  purposes of this  Section 4,  includes  the
     Common  Stock and any  additional  class of stock of the Company  having no
     preference as to dividends or distributions  on liquidation,  provided that
     the shares  purchasable  pursuant to this Warrant shall include only Common
     Stock in respect of which this Warrant is exercisable,  or shares resulting
     from any subdivision or combination of such Common Stock, or in the case of
     any reorganization, reclassification, consolidation, merger, or sale of the
     character referred to in Section 4(e) hereof, the stock or other securities
     or property provided for in such Section.

V. Cap Amount. Prior to Stockholder Approval (as defined in the Certificate of
Designation, Preferences and Rights attached as Exhibit A to the Securities
Purchase Agreement), in the event that Nasdaq Rule 4460(i) (or any successor
rule) applies to the Company, unless otherwise permitted by the Nasdaq SmallCap
Market or the Nasdaq National Market System if the Common Stock of the Company
trades on such market, in no event shall the Company be required to issue more
shares of Common Stock upon the exercise of the Warrant than the maximum number
of shares of Common Stock that the Company can without stockholder approval so
issue pursuant to such rule or rules, which, as of the date of initial issuance
of the shares of Preferred Stock and Warrants, shall be the amount indicated to
be the Cap Amount in the officer's certificate delivered pursuant to the
Securities Purchase Agreement. The Cap Amount shall be allocated pro-rata to the
Holders. A Holder's allocable portion of the Cap Amount shall be applicable to
both shares of Preferred Stock and Warrants held by it and shall be applied to
such Preferred Stock and Warrants on the basis of the time of conversion or
exercise, as the case may be, thereof.

VI. Issue Tax. The issuance of certificates for Warrant Shares upon the exercise
of this Warrant  shall be made  without  charge to the Holder of such shares for
any issuance tax or other costs in respect  thereof,  provided  that the Company
shall not be  required  to pay any tax which may be  payable  in  respect of any
transfer  involved in the  issuance and  delivery of any  certificate  in a name
other than the Holder.

VII. No Rights or Liabilities  as a Shareholder.  This Warrant shall not entitle
the Holder to any voting rights or other rights as a shareholder of the Company.
No provision of this Warrant, in the absence of affirmative action by the Holder
to purchase  Warrant  Shares,  and no mere  enumeration  herein of the rights or
privileges of the Holder, shall give rise to any liability of the Holder for the
Exercise  Price or as a shareholder  of the Company,  whether such  liability is
asserted by the Company or by creditors of the Company.

VIII. Transfer, Exchange, Redemption and Replacement of Warrant.

     A.  Restriction  on Transfer.  This  Warrant and the rights  granted to the
Holder are  transferable,  in whole or in part,  upon surrender of this Warrant,
together with a properly executed  assignment in the Form of Assignment attached
hereto as  Exhibit  2, at the  office or agency of the  Company  referred  to in
Section 8(e) below, provided,  however, that any transfer or assignment shall be
subject to the  provisions  of Section  5.1 and 5.2 of the  Securities  Purchase
Agreement.  Until due presentment  for  registration of transfer on the books of
the Company, the Company may treat the

                                      -10-

<PAGE>



registered  holder hereof as the owner and holder  hereof for all purposes,  and
the Company shall not be affected by any notice to the contrary. Notwithstanding
anything to the contrary  contained  herein,  the rights  described in Section 9
hereof are  assignable  only in accordance  with the  provisions of that certain
Registration  Rights  Agreement,  dated as of February 4, 1998, by and among the
Company and the other signatories thereto (the "Registration Rights Agreement").

     B.  Warrant  Exchangeable  for  Different  Denominations.  This  Warrant is
exchangeable  in  increments  of  10,000  or more of  Warrant  Shares,  upon the
surrender  hereof by the Holder at the office or agency of the Company  referred
to in Section 8(e) below,  for new  Warrants,  in the form hereof,  of different
denominations  representing in the aggregate the right to purchase the number of
shares  of  Common  Stock  which may be  purchased  hereunder,  each of such new
Warrants to  represent  the right to purchase  such number of shares as shall be
designated by the Holder of at the time of such surrender.

     C. Replacement of Warrant. Upon receipt of evidence reasonably satisfactory
to the Company of the loss,  theft,  destruction,  or mutilation of this Warrant
or, in the case of any such loss,  theft, or destruction,  upon delivery,  of an
indemnity agreement (or bond, in cases in which the Holder actually received the
original  or  replacement   certificate  for  such  Warrant  from  the  Company)
reasonably  satisfactory  in form and amount to the Company,  or, in the case of
any such  mutilation,  upon  surrender and  cancellation  of this  Warrant,  the
Company,  at its  expense,  will  execute and deliver,  in lieu  thereof,  a new
Warrant, in the form hereof, in such denominations as Holder may request.

     D. Cancellation; Payment of Expenses. Upon the surrender of this Warrant in
connection  with any  transfer,  exchange,  or  replacement  as provided in this
Section 8, this Warrant shall be promptly  canceled by the Company.  The Company
shall pay all issuance taxes (other than securities  transfer taxes) and charges
payable in connection with the preparation,  execution, and delivery of Warrants
pursuant to this Section 8.

     E. Warrant Register. The Company shall maintain, at its principal executive
offices (or such other  office or agency of the Company as it may  designate  by
notice to the Holder),  a register for this Warrant,  in which the Company shall
record the name and  address of the person in whose name this  Warrant  has been
issued,  as well as the name and address of each transferee and each prior owner
of this Warrant.

     F. Additional Restriction on Exercise or Transfer. Notwithstanding anything
to the contrary  contained herein,  the Warrants shall not be exercisable by the
Holder to the extent (but only to the extent)  that, if  exercisable  by Holder,
Holder or any of its  affiliates  (as defined under Rule 12b-2 of the Securities
Exchange Act of 1934, as amended)  would  beneficially  own in excess of 4.9% of
the shares of Common  Stock.  To the extent the above  limitation  applies,  the
determination  of whether the Warrants  shall be  exercisable  (vis-a-vis  other
securities owned by Holder) and of which Warrants shall be exercisable (as among
Warrants)  shall be in the sole  discretion of the Holder and  submission of the
Warrants  for  exercise  shall be deemed  to be the  Holder's  determination  of
whether such  Warrants are  exercisable  (vis-a-vis  other  securities  owned by
Holder) and of which warrants are exercisable  (among Warrants)  subject to such
aggregate  percentage  limitation.  No  prior  inability  to  exercise  Warrants
pursuant to this paragraph shall have any effect on the applicability

                                      -11-

<PAGE>



of the provisions of this paragraph with respect to any subsequent determination
of exercisability.  For the purposes of this paragraph, beneficial ownership and
all determinations and calculations,  including without limitation, with respect
to calculations of percentage ownership,  shall be determined in accordance with
Section 13(d) of the Securities Exchange Act of 1934, as amended, and Regulation
13D and G thereunder.  The  provisions of this paragraph may be implemented in a
manner  otherwise than in strict  conformity  with the terms this paragraph with
the approval of the Board of  Directors of the Company and the Holder:  (i) with
respect to any matter to cure any ambiguity  herein,  to correct this  paragraph
(or any portion hereof) which may be defective or inconsistent with the intended
4.9%  beneficial  ownership  limitation  herein  contained or to make changes or
supplements  necessary  or  desirable  to  properly  give  effect  to such  4.9%
limitation;  and (ii) with respect to any other matter, with the further consent
of the holders of a majority of the then outstanding shares of Common Stock. The
provisions  of this  paragraph  may be waived by Holder at its election upon not
less than  sixty-one  (61) days prior written notice from Holder to the Company,
including,  without  limitation,  a limited  waiver to  increase  the 4.9% limit
herein  contained  to  any  other  percentage  specified  by  such  Holder.  The
limitations  contained in this  paragraph  shall apply to a successor  Holder of
Warrants if, and to the extent,  elected by such successor  Holder  concurrently
with its acquisition of such Warrants, such election to be promptly confirmed in
writing  to the  Company  (provided  no  transfer  or series of  transfers  to a
successor  Holder or Holders shall be used by a Holder to evade the  limitations
contained in this paragraph).

IX.  Registration  Rights.  The  initial  holder of this  Warrant  (and  certain
assignees  thereof) is entitled  to the benefit of such  registration  rights in
respect  of the  Warrant  Shares  as are set  forth in the  Registration  Rights
Agreement.

X.  Notices.  Any notice  herein  required or  permitted to be given shall be in
writing and may be personally served or delivered by courier and shall be deemed
delivered at the time and date of receipt. The addresses for such communications
shall be:

                  If to the Company:

                           Pharmos Corporation
                           33 Wood Avenue South, Suite 466
                           Iselin, NJ  08830
                           Telecopy:  732-603-3532
                           Attention: Chief Financial Officer


                           with a copy to:
                           Ehrenreich Eilenberg Krause & Zivian, LLP
                           11 East 44th Street, 17th Floor
                           New York, NY  10017
                           Telecopy:  212-986-2399
                           Attention:  Adam D. Eilenberg

and if to the Holder,  at such address as Holder shall have  provided in writing
to the Company,  or at such other address as each such party furnishes by notice
given in accordance with this Section 9.

                                      -12-

<PAGE>




XI. Governing Law; Jurisdiction. This Warrant shall be governed by and construed
in  accordance  with the laws of the State of New York  applicable  to contracts
made and to be performed  in the State of New York.  The Company and each Holder
irrevocably  consent to the  jurisdiction  of the United States  federal  courts
located  in the  County  of New  York in the  State  of New  York in any suit or
proceeding based on or arising under this Warrant and irrevocably agree that all
claims in respect of such suit or  proceeding  may be determined in such courts.
The Company and each Holder  irrevocably  waives the defense of an  inconvenient
forum to the maintenance of such suit or proceeding. The Company and each Holder
further  agrees that  service of process  upon any other  party to this  Warrant
mailed by the first  class  mail  shall be  deemed  in every  respect  effective
service of process upon such party in any suit or proceeding  arising hereunder.
Nothing  herein  shall  affect  the right of the  Company or any Holder to serve
process in any other manner  permitted by law. The Company and each Holder agree
that a final  nonappealable  judgment  in any such suit or  proceeding  shall be
conclusive and may be enforced in other  jurisdictions  by suit on such judgment
or in any other lawful manner.

XII. Miscellaneous.

     A.  Amendments.  This  Warrant and any  provision  hereof may be amended or
waived by an  instrument  in writing  signed by the Company and the Holder to be
affected by such amendment or waiver.

     B. Descriptive  Headings.  The descriptive headings of the several Sections
of this  Warrant are inserted  for  purposes of  reference  only,  and shall not
affect the meaning or construction of any of the provisions hereof.

     C. Cashless Exercise. Notwithstanding anything to the contrary contained in
this  Warrant,  this Warrant may be exercised by  presentation  and surrender of
this Warrant to the Company at its  principal  executive  offices with a written
notice of the  Holder's  intention  to effect a cashless  exercise,  including a
calculation  of the  number of shares  of  Common  Stock to be issued  upon such
exercise in  accordance  with the terms hereof (a "Cashless  Exercise").  In the
event of a Cashless Exercise,  in lieu of paying the Exercise Price in cash, the
Holder  shall  surrender  this  Warrant for the number of shares of Common Stock
determined  by  multiplying  the  number  of  Warrant  Shares  to which it would
otherwise  be  entitled  by a  fraction,  the  numerator  of which  shall be the
difference  between the then current  Market Price per share of the Common Stock
and the Exercise Price,  and the denominator of which shall be such then current
Market Price per share of Common Stock.

     D.  Assignability.  This Warrant  shall be binding upon the Company and its
successors  and  assigns  and  shall  inure to the  benefit  of  Holder  and its
successors and assigns.  The Holder shall notify the Company upon the assignment
of this Warrant.

                                      * * *




                                      -13-

<PAGE>




     IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by its
duly authorized officer.


                               PHARMOS CORPORATION



                               By:     __________________________________
                               Name:   __________________________________
                               Title:  __________________________________



<PAGE>



                           FORM OF EXERCISE AGREEMENT

         (To be Executed by the Holder in order to Exercise the Warrant)

     The  undersigned  hereby  irrevocably   exercises  the  right  to  purchase
____________  of the  shares of common  stock of Pharmos  Corporation,  a Nevada
corporation (the "Company"),  evidenced by the attached  Warrant,  and [herewith
makes payment of the Exercise  Price with respect to such shares in full/ elects
to effect a Cashless  Exercise  pursuant  to the terms of the  Warrant],  all in
accordance with the conditions and provisions of said Warrant.

     (i) The  undersigned  agrees  not to offer,  sell,  transfer  or  otherwise
dispose of any Common  Stock  obtained  on exercise  of the  Warrant,  except in
compliance  with the Warrant and  otherwise  under  circumstances  that will not
result in a violation of the  Securities  Act of 1933, as amended,  or any state
securities laws.

     (ii) The undersigned  requests that stock  certificates  for such shares be
issued,  and a Warrant  representing  any unexercised  portion hereof be issued,
pursuant  to the  Warrant in the name of the  Holder  (or such  other  person or
persons indicated below) and delivered to the undersigned (or designee(s) at the
address (or addresses) set forth below:

Date: _______________________

                                       _____________________________________
                                       Signature of Holder

                                       _____________________________________
                                       Name of Holder (Print)

                                       _____________________________________
                                       Address:



                                       

<PAGE>



                               FORM OF ASSIGNMENT

     FOR VALUE RECEIVED,  the undersigned hereby sells,  assigns,  and transfers
all rights of the  undersigned  under the within  Warrant,  with  respect to the
number of shares of Common Stock covered thereby set forth hereinbelow, to:

Name of Assignee                     Address                   No. of Shares
- - ----------------                     -------                   -------------


, and hereby irrevocably constitutes and appoints ______________________________
as agent and  attorney-in-fact  to  transfer  said  Warrant  on the books of the
within-named corporation, with full power of substitution in the premises.


Date:____________, _____,

In the presence of



                                Name: __________________________________________


                                Signature: _____________________________________

                                   Title of Signing Officer or Agent (if any):

                                     ___________________________________________

                                     Address:___________________________________


                                     Note:   The above signature should
                                             correspond exactly with the
                                             name on the face of the within
                                             Warrant.


( 310531.12 - 8/6/98, 17:01 PM )



                                                        

<PAGE>



                                                                       EXHIBIT C


                          SECURITIES PURCHASE AGREEMENT


     This  SECURITIES  PURCHASE  AGREEMENT  ("Agreement")  is entered into as of
February 4, 1998, by and between Pharmos Corporation,  a Nevada corporation (the
"Company"),  with  headquarters  located  at 33 Wood  Avenue  South,  Suite 466,
Iselin, New Jersey 08830 and the purchasers (each a "Purchaser" and together the
"Purchasers")  set  forth on the  execution  pages  hereof,  with  regard to the
following:

                                    RECITALS

     A. The Company and Purchasers  are executing and delivering  this Agreement
in reliance  upon the exemption  from  securities  registration  afforded by the
provisions of Regulation D ("Regulation D"), as promulgated by the United States
Securities and Exchange Commission (the "SEC") under the Securities Act of 1933,
as amended (the "Securities Act").

     B. Purchasers  desire to purchase,  upon the terms and conditions stated in
this Agreement,  (i) Series C Convertible  Participating  Preferred Stock of the
Company  having  the  rights  set  forth  in the  Certificate  of  Designations,
Preferences  and Rights (the  "Certificate of  Designation")  attached hereto as
Exhibit A (the "Preferred Stock" or the "Convertible  Securities"),  which shall
be  convertible  into shares of the Company's  Common Stock,  par value $.03 per
share (the "Common Stock") and (ii) a Warrant in the form of Exhibit B hereto (a
"Warrant"  and, when taken together with all of the warrants  issued  hereunder,
the  "Warrants")  entitling the holder  thereof to purchase the number of shares
(the "Warrant  Shares") of Common Stock as set forth below. The shares of Common
Stock issuable upon  conversion of or otherwise  pursuant to the Preferred Stock
are referred to herein as the  "Conversion  Shares".  The Preferred  Stock,  the
Warrants and the Conversion  Shares are  collectively  referred to herein as the
"Securities."

     C. Contemporaneously with the execution and delivery of this Agreement, the
parties hereto are executing and delivering a Registration  Rights  Agreement in
the form attached  hereto as Exhibit C (the  "Registration  Rights  Agreement"),
pursuant to which the Company has agreed to provide certain  registration rights
under the Securities Act, the rules and regulations  promulgated  thereunder and
applicable state securities laws.

                                   AGREEMENTS

     NOW,  THEREFORE,  in consideration of their respective  promises  contained
herein and other good and valuable consideration, the receipt and sufficiency of
which are hereby  acknowledged,  the  Company  and  Purchasers  hereby  agree as
follows:



<PAGE>



                                    ARTICLE I
                         PURCHASE AND SALE OF SECURITIES

      A. Purchase of Preferred Stock and Warrants. Subject to the terms and
the satisfaction or waiver of the conditions set forth in this Agreement, the
issuance, sale and purchase of the Preferred Stock and Warrants shall be
consummated in two (2) separate closings. The first closing is hereinafter
referred to as the "First Closing" and the second closing is hereinafter
referred to as the "Second Closing" (the First Closing and the Second Closing
sometimes referred to herein as a "Closing"). The purchase price (the "Purchase
Price") per share of Preferred Stock shall be equal to $1,000. Each Purchaser
shall purchase the number of shares of Preferred Stock set forth on the
signature page executed by such Purchaser.

     (a) The Company may elect to consummate the Second Closing by (and only by)
delivering  a notice  satisfying  the  conditions  of this  Section (the "Second
Closing  Notice") to  Purchasers  at least three (3) business  days prior to the
date that the  Company  desires to  consummate  the Second  Closing.  The Second
Closing  may be  consummated  (i)  no  earlier  than  the  effectiveness  of the
Registration  Statement  contemplated by Section 2.3 of the Registration  Rights
Agreement (the "Registration Statement"), and (ii) no later than one hundred and
eighty (180) days following the date of the First Closing. In the Second Closing
Notice,  the Company shall  represent to Purchasers  that: (i) the  Registration
Statement is effective;  (ii) the Company elects to consummate the  transactions
contemplated  hereby as the Second Closing and (iii) the conditions set forth in
Section 7.2 hereof have been satisfied.

     (b) On the date of the  First  Closing,  subject  to the  satisfaction  (or
waiver) of the conditions set forth in Articles VI and VII, and  notwithstanding
any election by the Company, the Company shall issue and sell to each Purchaser,
and each  Purchaser  shall  purchase  from the  Company (i) 70% of the number of
shares of Preferred Stock set forth below such Purchaser's name on the signature
pages  hereof and (ii) a Warrant  entitling  the holder  thereof to purchase 100
Warrant Shares for each share of Preferred Stock purchased pursuant to the First
Closing.  The aggregate purchase price for the Securities purchased at the First
Closing shall be five million dollars ($5,000,000).

     (c) On the date of the Second Closing (if any), subject to the satisfaction
(or waiver) of the  conditions  set forth in  Articles  VI and VII,  the Company
shall issue and sell to each  Purchaser and each  Purchaser  shall purchase from
the Company (i) 30% of the number of shares of  Preferred  Stock set forth below
such Purchaser's name on the signature page hereof and (ii) a Warrant  entitling
the holder  thereof to purchase  100 Warrant  Shares for each share of Preferred
Stock purchased pursuant to the Second Closing. The aggregate purchase price for
the  Securities  purchased at the Second Closing (if any) shall be three million
dollars  ($3,000,000).  The  Conversion  Price of the  Preferred  Stock  and the
Exercise Price under the Warrant shall be the same for the Second Closing as for
the First Closing.


                                       -2-

<PAGE>



     B. Form of Payment.  At each of the First Closing and Second Closing,  each
Purchaser  shall pay the aggregate  Purchase  Price for the Preferred  Stock and
Warrant being  purchased by such  Purchaser by wire transfer to the Company,  in
accordance with the Company's written wiring  instructions,  against delivery of
duly executed  stock  certificates  for the same,  and the Company shall deliver
such Preferred Stock and certificates representing the Warrants against delivery
of such  aggregate  Purchase  Price.  The  obligations in this Agreement of each
Purchaser  shall be separate from the  obligations  of each other  Purchaser and
shall relate  solely to the number of shares to be purchased by such  Purchaser.
The  obligations of the Company with respect to each Purchaser shall be separate
from the  obligations of each other Purchaser and shall not be conditioned as to
any Purchaser upon the  performance of the  obligations of any other  Purchaser.
The  obligations of each Purchaser with respect to the Company shall be separate
from the obligations of each other Purchaser with respect to the Company. Except
as otherwise set forth in this  Agreement,  the  obligations  of each  Purchaser
shall not be conditioned  upon the  performance of the  obligations of any other
Purchaser.

     C. Closing Dates. Subject to the satisfaction (or waiver) of the conditions
set forth in Articles VI and VII below, the date and time of the issuance,  sale
and purchase of the Securities  pursuant to this Agreement  shall be (i) for the
First  Closing,  within two (2) business days of the execution of this Agreement
and (ii) for the Second  Closing,  on the day three (3) business days  following
receipt by all Purchasers of the Second  Closing  Notice from the Company.  Each
Closing  shall occur at 10:00 a.m.  Chicago  time, at the offices of Altheimer &
Gray, 10 S. Wacker Drive, Chicago, IL 60606.

                                   ARTICLE II.
                   PURCHASER'S REPRESENTATIONS AND WARRANTIES

     Each Purchaser  represents and warrants,  solely with respect to itself and
its  purchase  hereunder  and not with  respect  to any other  Purchaser  or the
purchase  hereunder by any other  Purchaser (and no Purchaser shall be deemed to
make or have any liability for any  representation or warranty made by any other
Purchaser),  to the Company as set forth in this Article II. No Purchaser  makes
any other  representations or warranties,  express or implied, to the Company in
connection  with the  transactions  contemplated  hereby  and any and all  prior
representations and warranties,  if any, which may have been made by a Purchaser
to the Company in connection with the transactions  contemplated hereby shall be
deemed to have been merged in this Agreement and any such prior  representations
and  warranties,  if any,  shall not survive the  execution and delivery of this
Agreement.

     A. Investment Purpose.  Purchaser is purchasing the Convertible  Securities
and the Warrants for  Purchaser's own account for investment only and not with a
view  toward or in  connection  with the public  sale or  distribution  thereof.
Purchaser  will not  resell the  Securities  except  pursuant  to sales that are
exempt from the  registration  requirements  of the  Securities Act and/or sales
registered under the Securities Act.  Purchaser  understands that Purchaser must
bear the economic risk of this  investment  indefinitely,  unless the Securities
are  registered  pursuant  to  the  Securities  Act  and  any  applicable  state
securities laws or an exemption from such  registration  is available,  and that
the Company has no present  intention of registering any such  Securities  other
than as contemplated

                                       -3-

<PAGE>



by the Registration  Rights  Agreement.  By making the  representations  in this
Section 2.1, the Purchaser does not agree to hold the Securities for any minimum
or other  specific  term and reserves the right to dispose of the  Securities at
any time in  accordance  with or  pursuant  to a  registration  statement  or an
exemption from registration under the Securities Act.

     B. Accredited Investor Status.  Purchaser is, and was at the time Purchaser
was offered the Securities,  an "accredited investor" as that term is defined in
Rule 501(a) of Regulation  D.  Purchaser is able to bear the economic risk of an
investment  in the  Securities,  is  able  to  afford  a  complete  loss of such
investment, and has carefully evaluated the merits and risks of such investment.

     C.  Reliance on  Exemptions.  Purchaser  understands  that the  Convertible
Securities  are being  offered and sold to Purchaser in reliance  upon  specific
exemptions from the  registration  requirements of the United States federal and
state  securities  laws and that the  Company  is  relying  upon the  truth  and
accuracy of, and Purchaser's  compliance with, the representations,  warranties,
agreements,  acknowledgments and understandings of Purchaser set forth herein in
order to determine the  availability  of such  exemptions and the eligibility of
Purchaser to acquire the Convertible Securities,  and Purchaser consents to such
reliance.

     D. Information. Purchaser and its counsel have been furnished all materials
relating to the business,  finances and  operations of the Company and materials
relating  to the offer and sale of the  Convertible  Securities  which have been
specifically requested by Purchaser. Purchaser has been afforded the opportunity
to ask questions of the Company and has received what  Purchaser  believes to be
complete and satisfactory answers to any such inquiries.  Neither such inquiries
nor any other due diligence  investigation  conducted by Purchaser or any of its
representations  shall modify,  amend or affect Purchaser's right to rely on the
Company's  representations  and warranties  contained in Article III.  Purchaser
understands that Purchaser's investment in the Securities involves a high degree
of risk.

     E. Governmental Review. Purchaser understands that no United States federal
or state agency or any other  government or governmental  agency has passed upon
or made any  recommendation  or  endorsement  of the Securities or an investment
therein.

     F. Transfer or Resale. Purchaser understands that (i) except as provided in
the  Registration  Rights  Agreement,  the Securities  have not been and are not
being  registered under the Securities Act or any state securities laws, and may
not be transferred  unless  subsequently  registered  thereunder or an exemption
from such  registration  is available  (which  exemption  the Company  expressly
agrees may be established as  contemplated in clauses (b) and (c) of Section 5.1
hereof); (ii) any sale of such Securities made in reliance on Rule 144 under the
Securities Act (or a successor rule) ("Rule 144") may be made only in accordance
with the terms of said Rule and  further,  if said Rule is not  applicable,  any
resale of such Securities  without  registration  under the Securities Act under
circumstances  in which the seller may be deemed to be an  underwriter  (as that
term is defined in the Securities  Act) may require  compliance  with some other
exemption  under the  Securities  Act or the rules  and  regulations  of the SEC
thereunder;  and (iii)  neither the  Company  nor any other  person is under any
obligation to register such Securities under the Securities Act or any state

                                       -4-

<PAGE>



securities  laws or to comply  with the terms and  conditions  of any  exemption
thereunder  (in  each  case,  other  than  pursuant  to  this  Agreement  or the
Registration Rights Agreement).

     G. Legends.  Purchaser  understands that,  subject to Article V hereof, the
certificates  for  the  Convertible  Securities,  and  until  such  time  as the
Conversion  Shares have been registered under the Securities Act as contemplated
by the  Registration  Rights  Agreement  or  otherwise  may be sold by Purchaser
pursuant to Rule 144, the  certificates  for the  Conversion  Shares will bear a
restrictive legend (the "Legend") in the following form:

     THE SECURITIES  REPRESENTED BY THIS  CERTIFICATE  HAVE NOT BEEN  REGISTERED
     UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR THE SECURITIES LAWS OF ANY
     STATE OF THE UNITED STATES.  THE SECURITIES  REPRESENTED  HEREBY MAY NOT BE
     OFFERED OR SOLD OR  OTHERWISE  TRANSFERRED  IN THE ABSENCE OF AN  EFFECTIVE
     REGISTRATION  STATEMENT FOR THE SECURITIES UNDER APPLICABLE SECURITIES LAWS
     OR UNLESS OFFERED,  SOLD OR TRANSFERRED  PURSUANT TO AN AVAILABLE EXEMPTION
     FROM THE REGISTRATION REQUIREMENTS OF THOSE LAWS.

     H. Authorization;  Enforcement.  This Agreement and the Registration Rights
Agreement  have been duly and validly  authorized,  executed  and  delivered  on
behalf  of  Purchaser  and  are  valid  and  binding   agreements  of  Purchaser
enforceable against Purchaser in accordance with their terms.

     I. Residency.  Purchaser is a resident of the  jurisdiction set forth under
Purchaser's name on the signature page hereto executed by Purchaser.

     J. Acknowledgments  Regarding Placement Agent.  Purchaser acknowledges that
Gemini Capital,  a division of R.D.  Kushner & Co., is acting as placement agent
(the  "Placement  Agent") for the  Securities  being offered  hereby and will be
compensated  by the  Company  for  acting in such  capacity.  Purchaser  further
acknowledges  that the  Placement  Agent has acted solely as placement  agent in
connection with the offering of Securities by the Company,  that the information
and data provided to Purchaser in connection with the transactions  contemplated
hereby have not been  subjected to  independent  verification  by the  Placement
Agent,  and that the Placement  Agent makes no  representation  or warranty with
respect to the  accuracy  or  completeness  of such  information,  data or other
related disclosure  material.  Purchaser further acknowledges that in making its
decision to enter into this  Agreement and purchase the Securities it has relied
on its own  examination  of the  Company and the terms of, and  consequences  of
holding,  the Securities.  Purchaser further acknowledges that the provisions of
this Section 2.10 are for the benefit of, and may be enforced by, the  Placement
Agent.


                                       -5-

<PAGE>



                                  ARTICLE III.
                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY

     The Company represents and warrants to each Purchaser that:

     A. Organization and Qualification. The Company and each of its subsidiaries
is a corporation  duly organized,  validity  existing and in good standing under
the laws of the  State of  Nevada  and has the  requisite  corporate  power  and
authority  to own its  properties  and to carry  on its  business  as now  being
conducted.  The  Company and each of its  subsidiaries  is duly  qualified  as a
foreign corporation to do business and is in good standing in every jurisdiction
where the failure to so qualify would have a Material Adverse Effect.  "Material
Adverse  Effect" means any material  adverse  effect on either (i) the business,
operations,  properties,  financial condition, operating results or prospects of
the Company and its  subsidiaries,  taken as a whole on a consolidated  basis or
(ii) the transactions contemplated hereby.

     B. Authorization;  Enforcement. (a) The Company has the requisite corporate
power and authority to enter into and perform this  Agreement,  the Warrants and
the  Registration  Rights  Agreement,  and to issue and sell,  and  perform  its
obligations  with  respect to, the  Convertible  Securities  and the Warrants in
accordance  with  the  terms  hereof  and to  issue  the  Conversion  Shares  in
accordance  with the terms and conditions of the  Certificate of Designation and
the Warrant  Shares in accordance  with the terms and conditions of the Warrant;
(b)  the  execution,   delivery  and  performance  of  this  Agreement  and  the
Registration  Rights  Agreement by the Company and the consummation by it of the
transactions  contemplated  hereby and thereby (including without limitation the
issuance of the Convertible  Securities and the Warrants and the reservation for
issuance and issuance of the Conversion Shares and the Warrant Shares) have been
duly  authorized by all necessary  corporate  action and, except as set forth on
Schedule 3.2 hereof,  no further consent or  authorization  of the Company,  its
board of directors,  or its stockholders or any other person,  body or agency is
required with respect to any of the transactions  contemplated hereby or thereby
(whether under rules of the Nasdaq SmallCap Market or the Nasdaq National Market
System ("Nasdaq"), the National Association of Securities Dealers or otherwise);
(c) this  Agreement,  the  Registration  Rights  Agreement  and the  Convertible
Securities  have been duly executed and  delivered by the Company;  and (d) this
Agreement,  the  Registration  Rights  Agreement and the Convertible  Securities
constitute  legal,  valid and binding  obligations  of the  Company  enforceable
against the Company in accordance with their terms.

     C. Capitalization. The capitalization of the Company as of the date hereof,
including  the  authorized  capital  stock,  the  number  of shares  issued  and
outstanding,  the  number  of  shares  reserved  for  issuance  pursuant  to the
Company's  stock  option  plans,  the  number of shares  reserved  for  issuance
pursuant to securities (other than the Convertible  Securities and the Warrants)
exercisable  for, or convertible  into or exchangeable  for any shares of Common
Stock and the  number  of shares to be  initially  reserved  for  issuance  upon
conversion of the Convertible Securities and the exercise of the Warrants is set
forth on Schedule  3.3.  All of such  outstanding  shares of capital  stock have
been, or upon issuance will be, validly issued,  fully paid and  non-assessable.
No shares of capital stock of the Company (including the Preferred Stock and the
Conversion Shares) are subject

                                       -6-

<PAGE>



to preemptive  rights or any other  similar  rights of the  stockholders  of the
Company or any liens or encumbrances  (except for liens and encumbrances created
by or through  the  actions of the  holders of such  capital  stock).  Except as
disclosed in Schedule  3.3, as of the date of this  Agreement,  (i) there are no
outstanding  options,  warrants,  scrip,  rights  to  subscribe  for,  calls  or
commitments  of any  character  whatsoever  relating to, or securities or rights
convertible into or exercisable or exchangeable for, any shares of capital stock
of  the  Company  or  any  of  its  subsidiaries,  or  contracts,   commitments,
understandings  or arrangements by which the Company or any of its  subsidiaries
is or may  become  bound to issue  additional  shares  of  capital  stock of the
Company  or any  of its  subsidiaries,  and  (ii)  there  are no  agreements  or
arrangements  under which the Company or any of its subsidiaries is obligated to
register the sale of any of its or their  securities  under the  Securities  Act
(except  the  Registration  Rights  Agreement).  The Company  has  furnished  to
Purchaser true and correct copies of the Company's  Certificate of Incorporation
as currently  in effect  ("Certificate  of  Incorporation"),  and the  Company's
By-laws as  currently  in effect (the  "By-laws").  The Company has set forth on
Schedule 3.3 all  instruments  and  agreements  (other than the  Certificate  of
Incorporation and By-laws) governing securities  convertible into or exercisable
or  exchangeable  for Common Stock of the Company (and the Company shall provide
to Purchaser  copies thereof upon the request of  Purchaser).  The Company shall
provide  Purchaser  with a written update of this  representation  signed by the
Company's  Chief Executive  Officer or Chief Financial  Officer on behalf of the
Company as of the date of the Closing.

     D. Issuance of Shares.  The  Conversion  Shares and Warrant Shares are duly
authorized and reserved for issuance,  and, upon  conversion of the  Convertible
Securities  in  accordance  with the terms hereof and  thereof,  will be validly
issued,  fully paid and  non-assessable,  and free from all taxes, liens, claims
and  encumbrances  (except  for those  encumbrances  created by or  through  the
actions  of  a  Purchaser  or  otherwise  arising  under  this  Agreement,   the
Registration  Rights  Agreement  or the  Warrants)  and will not be  subject  to
preemptive  rights or other similar rights of stockholders  of the Company.  The
Convertible  Securities  and  Warrants  are duly  authorized  and  reserved  for
issuance,  and are validly issued, fully paid and non-assessable,  and free from
all taxes, liens claims and encumbrances  (except for those encumbrances created
by or through  the  actions  of a  Purchaser  or  otherwise  arising  under this
Agreement,  the  Registration  Rights Agreement or the Warrants) and are not and
will not be subject to preemptive rights or other similar rights of stockholders
of the Company.  The Board of Directors of the Company has unanimously  approved
the  issuance of shares of Common Stock upon  conversion  of shares of Preferred
Stock and upon the exercise of the Warrants  pursuant to the terms hereof in the
aggregate in excess of twenty percent (20%) of the outstanding  shares of Common
Stock (the "Rule  4460(i)  Authorization").  Accordingly,  no further  corporate
authorization  or approval (other than the  Stockholder  Approval (as defined in
Section  4.14)) is required  under the rules of the Nasdaq  with  respect to the
transaction contemplated by this Agreement,  including,  without limitation, the
issuance  of the  Conversion  Shares and the  Warrant  Shares and the  inclusion
thereof on the Nasdaq.

     E. No Conflicts. The execution,  delivery and performance of this Agreement
and the Registration  Rights  Agreement by the Company,  and the consummation by
the Company of the  transactions  contemplated  hereby and  thereby  (including,
without limitation, the issuance and reservation for issuance, as applicable, of
the Convertible Securities and Conversion Shares) will not

                                       -7-

<PAGE>



(a) result in a violation of the Certificate of  Incorporation  or By-laws,  (b)
conflict  with,  or constitute a default (or an event which with notice or lapse
of time or both would become a default)  under,  or give to others any rights of
termination,   amendment,   acceleration  or  cancellation  of,  any  agreement,
indenture or  instrument  to which the Company or any of its  subsidiaries  is a
party  (except  for  such   conflicts,   defaults,   terminations,   amendments,
accelerations, and cancellations as would not, individually or in the aggregate,
have a Material Adverse Effect),  or (c) result in a violation of any law, rule,
regulation,  order,  judgment or decree  (including,  without  limitation,  U.S.
federal and state securities laws and regulations)  applicable to the Company or
any of its subsidiaries, or by which any property or asset of the Company or any
of its subsidiaries,  is bound or affected, which violation is reasonably likely
to  have  a  Material  Adverse  Affect.  Neither  the  Company  nor  any  of its
subsidiaries  is in violation of its  Certificate of  Incorporation,  by-laws or
other  organizational  documents,  and  neither  the  Company  nor  any  of  its
subsidiaries  is in default  (and no event has  occurred  which,  with notice or
lapse of time or both,  would  put the  Company  or any of its  subsidiaries  in
default)  under,  nor has there occurred any event giving others (with notice or
lapse of time or both) any rights of  termination,  amendment,  acceleration  or
cancellation of, any agreement,  indenture or instrument to which the Company or
any of its  subsidiaries is a party,  except for possible  defaults or rights as
would not, individually or in the aggregate, have a Material Adverse Effect. The
business of the Company and its subsidiaries is not being  conducted,  and shall
not be conducted so long as a Purchaser owns any of the Securities, in violation
of any law,  ordinance,  rule,  regulation,  order,  judgment  or  decree of any
governmental   entity,   court  or  arbitration  tribunal  except  for  possible
violations  the sanctions for which either singly or in the aggregate  would not
have a Material Adverse Effect. Except as set forth on Schedule 3.5, the Company
is not  required to obtain any consent,  authorization  or order of, or make any
filing or registration with, any court or governmental  agency or any regulatory
or self-regulatory agency in order for it to execute,  deliver or perform any of
its obligations under this Agreement or the Registration  Rights Agreement or to
perform its  obligations  in  accordance  with the terms hereof or thereof.  The
Company  is not in  violation  of the  listing  requirements  of Nasdaq  and the
Company  is not  currently  aware of any  facts  or  circumstances  which  would
reasonably  cause the Company to believe that the Common Stock will be de-listed
in the foreseeable future.

     F.  Registration  and SEC Documents.  The Common Stock is registered  under
Section 12 of the  Securities  Exchange Act of 1934,  as amended (the  "Exchange
Act") and has been so registered since January 30, 1984.  Except as disclosed in
Schedule 3.6, since December 31, 1995, the Company has timely filed all reports,
schedules, forms, statements and other documents required to be filed by it with
the SEC pursuant to the reporting  requirements  of the Exchange Act (all of the
foregoing  filed after December 31, 1995 and all exhibits  included  therein and
financial  statements  and  schedules  thereto  and  documents  incorporated  by
reference therein, being referred to herein as the "SEC Documents"). The Company
has delivered to each Purchaser  true and complete  copies of the SEC Documents,
except for exhibits,  schedules and  incorporated  documents  (the SEC documents
filed  prior  to the  date  hereof,  the  "Filed  SEC  Documents").  As of their
respective  dates, the SEC Documents  complied in all material respects with the
requirements  of the  Exchange  Act and the  rules  and  regulations  of the SEC
promulgated  thereunder  applicable  to the SEC  Documents,  and none of the SEC
Documents,  at the time they  were  filed  with the SEC,  contained  any  untrue
statement of a material  fact or omitted to state a material fact required to be
stated therein or necessary in order to

                                       -8-

<PAGE>



make the statements therein, in light of the circumstances under which they were
made, not misleading. To the best of Company's knowledge, none of the statements
made in any such SEC  Documents  is,  or has been,  required  to be  updated  or
amended under  applicable law. The financial  statements of the Company included
in the SEC  Documents  have been  prepared  in  accordance  with U.S.  generally
accepted  accounting  principles,  consistently  applied,  and the  published or
otherwise  promulgated  rules and  regulations  of the SEC  during  the  periods
involved (except (i) as may be otherwise indicated in such financial  statements
or the notes thereto,  or (ii) in the case of unaudited interim  statements,  to
the extent they do not include footnotes or are condensed or summary statements)
and present fairly in all material respects the consolidated  financial position
of the Company and its consolidated subsidiaries as of the dates thereof and the
consolidated  results of their  operations  and cash flows for the periods  then
ended  (subject,  in the case of  unaudited  statements,  to normal,  immaterial
year-end audit  adjustments).  Except as set forth in the most recent  financial
statements of the Company  included in the Filed SEC Documents,  the Company has
no liabilities,  contingent or otherwise,  other than (i)  liabilities  incurred
subsequent to the date of such  financial  statements in the ordinary  course of
business and (ii)  obligations  under contracts and commitments  incurred in the
ordinary course of business and not required under generally accepted accounting
principles to be reflected in such financial statements,  in the case of each of
clauses (i) and (ii) next above,  which are in nature and amount consistent with
the  Company's  past  business  practices  and are  consistent,  in all material
respects, with the budgets of the Company for the years 1997 and 1998. The Filed
SEC Documents contain a complete and accurate list of all material  undischarged
written or oral contracts,  agreements, leases or other instruments to which the
Company or any  subsidiary is a party or by which the Company or any  subsidiary
is bound or to which  any of the  properties  or assets  of the  Company  or any
subsidiary is subject (each a "Contract"). None of the Company, its subsidiaries
or, to the best knowledge of the Company,  any of the other parties thereto,  is
in breach or violation of any Contract,  which breach or violation  would have a
Material Adverse Effect.  No event,  occurrence or condition exists which,  with
the lapse of time,  the  giving of  notice,  or both,  would  become a breach or
default by the Company or its  subsidiaries  under any Contract  which breach or
default would have a Material Adverse Effect.

     G. Absence of Certain Changes.  Since September 30, 1997, there has been no
material  adverse  change in the  business,  properties,  operations,  financial
condition,  results of  operations or prospects of the Company taken as a whole,
except as disclosed in Schedule 3.7.

     H. Absence of Litigation.  Except as disclosed in Schedule 3.8, there is no
action,  suit,  proceeding,  inquiry  or  investigation  before or by any court,
public board, governmental agency or authority, or self-regulatory  organization
or body pending or, to the knowledge of the Company or any of its  subsidiaries,
threatened against or affecting the Company, any of its subsidiaries,  or any of
their respective  directors or officers in their capacities as such,  wherein an
unfavorable decision,  ruling or finding would have a Material Adverse Effect or
would adversely affect the transactions contemplated by this Agreement or any of
the documents  contemplated  hereby or which would adversely affect the validity
or enforceability  of, or the authority or ability of the Company to perform its
obligations  under, this Agreement or any of such other documents.  There are no
facts  which,  if  known by a  potential  claimant  or  governmental  agency  or
authority,  would be  reasonably  likely to give  rise to a claim or  proceeding
which, if asserted or conducted with results unfavorable

                                       -9-

<PAGE>



to the Company or any of its subsidiaries,  would be reasonably likely to have a
Material Adverse Effect.

     I.  Disclosure.  No  information  relating to or concerning the Company set
forth  in this  Agreement  or  provided  to  Purchaser  in  connection  with the
transactions contemplated hereby contains an untrue statement of a material fact
or omits to state a material fact necessary in order to make the statements made
herein or therein, in light of the circumstances under which they were made, not
misleading.  The Company has no knowledge  of any adverse  fact or  circumstance
with respect to the Company which is material (within the meaning of the federal
securities laws of the United States) which has not been publicly disclosed. For
purposes of this  Agreement,  the Company shall be deemed to have knowledge of a
fact or  circumstance  if an officer of the Company knew,  or reasonably  should
have known,  of such matter after due  inquiry.  The Company has not provided to
the Purchasers any material non-public information.

     J. Acknowledgment  Regarding  Purchaser's  Purchase of the Securities.  The
Company  acknowledges  and agrees  that  Purchaser  is not acting as a financial
advisor or fiduciary of the Company (or in any similar capacity) with respect to
this Agreement or the transactions  contemplated hereby, that this Agreement and
the  transactions   contemplated  hereby,  and  the  relationship  between  each
Purchaser and the Company,  are  "arms-length",  and that any statement  made by
Purchaser,  or any of its  representatives  or agents,  in connection  with this
Agreement  or  the  transactions   contemplated   hereby  is  not  advice  or  a
recommendation,  is merely incidental to Purchaser's  purchase of the Securities
and has not been relied upon in any way by the Company, its officers,  directors
or  other  representatives;   provided  that  the  Company  has  relied  on  the
Purchaser's  "accredited  investor"  representations  set forth in Article II of
this Agreement.  The Company further  represents to Purchaser that the Company's
decision to enter into this Agreement and the transactions  contemplated  hereby
has been  based  solely on an  independent  evaluation  by the  Company  and its
representatives.

     K.  Current  Public  Information.  The  Company is  currently  eligible  to
register the resale of the Conversion Shares on a registration statement on Form
S-3 under the Securities Act.

     L. No General  Solicitation.  Neither the Company nor any person  acting on
behalf of the Company has conducted any "general  solicitation," as described in
Rule 502(C)  under  Regulation  D, with respect to any of the  Securities  being
offered hereby.

     M. No Integrated Offering.  Neither the Company, nor any of its affiliates,
nor any person  acting on its or their behalf,  has directly or indirectly  made
any offers or sales of any security or solicited  any offers to buy any security
under  circumstances that would prevent the parties hereto from consummating the
transactions  contemplated  hereby  pursuant to an exemption  from  registration
under the  Securities  Act  pursuant  to the  provisions  of  Regulation  D. The
transactions  contemplated hereby are exempt from the registration  requirements
of  the  Securities  Act,  assuming  the  accuracy  of the  representations  and
warranties  herein  contained of each Purchaser to the extent  relevant for such
determination.


                                      -10-

<PAGE>



     N. No Brokers. The Company has taken no action which would give rise to any
claim by any person for brokerage commissions, finder's fees or similar payments
by Purchaser relating to this Agreement or the transactions contemplated hereby,
except for dealings with the Placement Agent (the fees of which shall be paid in
full by the Company). The Company will indemnify each Purchaser from and against
any fees and expenses sought or other claims made by the Placement Agent.

     O.  Acknowledgment  of Dilution.  The number of Conversion  Shares issuable
upon  conversion of the  Convertible  Securities may increase  substantially  in
certain  circumstances,  including the circumstance wherein the trading price of
the Common Stock declines.  The Company's  executive officers and directors have
studied and  understand  the nature of the  securities  being sold hereunder and
recognize that they have a potential  dilutive effect. The board of directors of
the Company has concluded in its good faith business judgment that such issuance
is in the best  interests  of the  Company  and its  stakeholders.  The  Company
acknowledges  that its obligation to issue Conversion  Shares upon conversion of
the Convertible  Securities and the Warrant Shares upon exercise of the Warrants
is binding upon it and enforceable in accordance with the applicable  provisions
of  this  Agreement,   the  Certificate  of  Designation,   the  Warrants,   the
Registration  Rights  Agreement  and  the  other  agreements,   instruments  and
documents delivered in connection with this Agreement regardless of the dilution
that such issuance may have on the ownership  interests of other stockholders or
stakeholders.

     P. Intellectual Property.  Each of the Company and its subsidiaries owns or
possesses   adequate  and  enforceable   rights  to  use  all  patents,   patent
applications,  trademarks,  trademark applications,  trade names, service marks,
copyrights, copyright applications,  licenses, know-how (including trade secrets
and  other   unpatented   and/or   unpatentable   proprietary  or   confidential
information,  systems or procedures)  and other similar  rights and  proprietary
knowledge (collectively, "Intangibles") used or necessary for the conduct of its
business as now being  conducted  and as  previously  described in the Company's
Annual Report on Form 10-K for its most recently  ended fiscal year,  except for
such  Intangibles  which,  if not  possessed  by the  Company,  would not have a
Material  Adverse Effect on the Company.  Neither the Company nor any subsidiary
of the Company infringes on or is in conflict with any right of any other person
with respect to any Intangibles nor is there any claim of infringement made by a
third party against or involving the Company or any of its  subsidiaries,  which
infringement,  conflict  or  claim,  individually  or in the  aggregate,  if the
subject of an  unfavorable  decision,  ruling or finding,  would have a Material
Adverse Effect.

     Q.  Foreign  Corrupt  Practices.  Neither  the  Company,  nor  any  of  its
subsidiaries,  nor any director, officer, agent, employee or other person acting
on behalf of the  Company or any  subsidiary  has,  in the course of his actions
for, or on behalf of, the  Company,  used any  corporate  funds for any unlawful
contribution,  gift,  entertainment  or  other  unlawful  expenses  relating  to
political activity;  made any direct or indirect unlawful payment to any foreign
or domestic government official or employee from corporate funds; violated or is
in violation of any provision of the U.S. Foreign Corrupt Practices Act of 1977,
as amended; or made any bribe, rebate,  payoff,  influence payment,  kickback or
other  unlawful  payment  to any  foreign or  domestic  government  official  or
employee.


                                      -11-

<PAGE>



     R. Key Employees. Each Key Employee (as defined below) is currently serving
the Company in the capacity disclosed in Schedule 3.18. No Key Employee,  to the
best of the  knowledge  of the  Company  and  its  subsidiaries,  is,  or is now
expected to be, in violation of any material  term of any  employment  contract,
confidentiality,    disclosure    or    proprietary    information    agreement,
non-competition agreement, or any other contract or agreement or any restrictive
covenant, and the continued employment of each Key Employee does not subject the
Company or any of its  subsidiaries  to any liability with respect to any of the
foregoing  matters.  The  Company  is not aware  that any Key  Employee  has any
intention to terminate or limit his employment with, or services to, the Company
or  any of  its  subsidiaries,  nor is any  such  Key  Employee  subject  to any
constraints  (e.g.,  litigation) which would cause such employee to be unable to
devote  his  full  time and  attention  to such  employment  or  services.  "Key
Employee" means each of Dr. Haim Aviv, Dr. Gadi Riesenfeld, Dr. Anat Biegon, and
Mr. Robert Cook.

                                   ARTICLE IV.
                                    COVENANTS

     A. Best Efforts.  The Company shall use its best efforts to satisfy  timely
each of the  conditions  described  in  Articles  VI and VII of this  Agreement;
provided,  however,  that  in  the  case  of  Section  7.2,  such  best  efforts
requirement set forth in this Section 4.1 shall only apply in the event that the
Company elects to proceed with the Second Closing by delivering a Second Closing
Notice.

     B. Securities Laws. The Company agrees to file a Form D with respect to the
Securities  with the SEC as required  under  Regulation  D and to provide a copy
thereof  to each  Purchaser  on or prior to the date of the First  Closing.  The
Company agrees to file a Form 8-K disclosing this Agreement and the transactions
contemplated  hereby with the SEC within ten (10) days following the date of the
First Closing. The Company shall, on or prior to the date of each Closing,  take
such  action  as is  necessary  to sell  the  Securities  to each  Purchaser  in
accordance with  applicable  securities laws of the states of the United States,
and shall provide  evidence of any such action so taken to each  Purchaser on or
prior  to the  date of  each  Closing.  Without  limiting  any of the  Company's
obligations  under this  Agreement,  the  Registration  Rights  Agreement or the
Certificate  of  Designation,  from and  after  the date of the  First  Closing,
neither the Company  nor any person  acting on its behalf  shall take any action
which  would  adversely  affect  any  exemptions  from  registration  under  the
Securities Act with respect to the transactions contemplated hereby.

     C. Reporting Status. So long as any Purchaser  beneficially owns any of the
Securities,  the Company shall timely file all reports required to be filed with
the SEC pursuant to the Exchange  Act, and the Company  shall not  terminate its
status as an issuer  required to file reports under the Exchange Act even if the
Exchange  Act  or  the  rules  and  regulations  thereunder  would  permit  such
termination.

     D. Use of Proceeds. The Company shall use the proceeds from the sale of the
Preferred Stock only for working capital and general corporate purposes.


                                      -12-

<PAGE>



     E.  Restriction on Issuance of Securities.  (a) For a period of one hundred
and eighty (180) days following the date of the First Closing, the Company shall
not  issue  or  agree to  issue,  (except  (i) to  Purchasers  pursuant  to this
Agreement,  (ii) pursuant to a merger or  acquisition  or sale of assets entered
into by the  Company  undertaken  in the  business  judgement  of the  Board  of
Directors  of the Company,  the primary  purpose of which is not to raise equity
capital or (iii) a public  offering  of the  Company's  securities),  any equity
securities  at a price  less  than the  fair  market  value  thereof  (less  any
customary  underwriting  discount) or any variably  priced equity  securities or
equity  like  securities  of  the  Company  (or  any  variably  priced  security
convertible  into or exercisable or  exchangeable,  directly or indirectly,  for
equity or equity like  securities of the Company) (each of the foregoing being a
"Restricted Security");  provided, however, that the foregoing restriction shall
apply only for so long as the  Purchasers  continue to hold thirty percent (30%)
of the Preferred Stock (or equity securities into which such Preferred Stock was
converted) on the date of such  issuance.  Following such one hundred and eighty
(180) day period, the Company may issue Restricted  Securities provided that any
securities  so issued  (and any  securities  issued  or  issuable,  directly  or
indirectly,  upon  conversion,  exercise or exchange of any of such  securities)
shall be  ineligible  for  conversion,  exercise,  exchange,  sale,  resale  and
registration under Federal and state securities laws for a period of two hundred
and seventy (270) days following the First Closing.

     F.  Expenses.  The Company  shall pay to each  Purchaser,  or, at the First
Closing such  Purchasers  shall be entitled to withhold from the Purchase Price,
reimbursement for the expenses  reasonably  incurred by CC Investments,  LDC and
its affiliates  and advisors in connection  with the  negotiation,  preparation,
execution,  and  delivery  of this  Agreement  and the  other  agreements  to be
executed in connection herewith, including, without limitation, such Purchaser's
and its affiliates' and advisors' due diligence and attorneys' fees and expenses
(the "Expenses");  provided,  however, that such reimbursement of Expenses shall
not  exceed  $50,000.  In  addition,  from  time to time  thereafter,  upon  any
Purchaser's  written  request,  subject to such $50,000 limit, the Company shall
pay to such Purchaser  such  Expenses,  if any, not so paid at the First Closing
and/or covered by such payment,  in each case to the extent reasonably  incurred
by such Purchaser.

     G.  Information.  For so long as the  Purchasers  continue  to hold  twenty
percent  (20%) of the  Preferred  Stock (or  equity  securities  into which such
Preferred Stock was converted), the Company agrees to send the following reports
to each Purchaser  until such Purchaser  transfers,  assigns or sells all of its
Securities:  (a) within three (3) business days after the filing with the SEC, a
copy of its Annual Report on Form 10-K, its Quarterly  Reports on Form 10-Q, any
proxy  statements  and any Current  Reports on Form 8-K;  and (b) within one (1)
business day after release,  copies of all press releases  issued by the Company
or any of its  subsidiaries.  The Company further agrees to promptly  provide to
any Holder any information with respect to the Company,  its properties,  or its
business or Holder's investment as such Holder may reasonably request; provided,
however,  that the Company shall not be required to give any Holder any material
non-public  information.  If any  information  requested  by a  Holder  from the
Company contains material non-public  information,  the Company shall inform the
Holder in writing that the information  requested  contains material  non-public
information and shall in no event provide such information to Holder without the
express prior written consent of such Holder after being so informed.


                                      -13-

<PAGE>



     H. Conduct of Business.  The Company shall not make any investment or enter
into any line of business  which is  inconsistent  with the  description  of the
Company's business as set forth in the SEC Documents.

     I. Listing.  For so long as any Purchaser owns any of the  Securities,  the
Company shall continue the listing and trading of its Common Stock on the Nasdaq
SmallCap Market,  the Nasdaq National Market System, the New York Stock Exchange
or the American Stock Exchange,  secure and maintain  listing and trading of the
Conversion  Shares  and  Warrant  Shares  on such  exchange,  and  comply in all
respects with the Company's  reporting,  filing and other  obligations under the
by-laws or rules of such exchange.

     J. Prospectus  Delivery  Requirement.  Each Purchaser  understands that the
Securities Act may require delivery of a prospectus relating to the Common Stock
in connection with any sale thereof  pursuant to a registration  statement under
the  Securities  Act covering  the resale by such  Purchaser of the Common Stock
being sold,  and each  Purchaser  shall  comply with the  applicable  prospectus
delivery requirements of the Securities Act in connection with any such sale.

     K.  Intentional  Acts or  Omissions.  The Company  shall not  intentionally
perform any act which if  performed,  or  intentionally  omit to perform any act
which,  if omitted to be performed,  would prevent or excuse the  performance of
this  Agreement  or any  of the  transactions  contemplated  hereby  (including,
without  limitation,  pursuant to any  agreements  or documents  obtained by the
Company as a condition to any Closing hereunder).

     L.  Corporate  Existence.  So long as any Purchaser  beneficially  owns any
Preferred Stock, the Company shall maintain its corporate  existence,  except in
the event of a merger,  consolidation or sale of all or substantially all of the
Company's  assets  which  complies  with  Section  XI.C  of the  Certificate  of
Designation.

     M. Share Authorization.  The Company covenants and agrees the Company shall
solicit  and obtain  Stockholder  Approval  (as  defined in the  Certificate  of
Designation)  within the time periods set forth in Article VI of the Certificate
of Designation.

     N. Hedging  Transactions.  The Company  understands that some or all of the
Purchasers are so-called  "hedge" funds and the Company hereby  expressly agrees
that each  Purchaser  shall not in any way be prohibited or restricted  from any
purchases or sales of any securities or other instruments of, or related to, the
Company or any of its securities,  including,  without  limitation,  puts, call,
futures  contracts,  short sales and hedging and  arbitrage  transactions.  Each
Purchaser acknowledges that such purchases,  sales and other transactions may be
subject to various  Federal and state  securities laws and agrees to comply with
all such  applicable  securities  laws in  connection  therewith  and that  such
purchases,  sales and other transactions will not be effected with the intention
of reducing the price of the Common Stock.  Each Purchaser  agrees that it shall
not  transfer  the  Preferred  Stock or Warrants to any third party  unless such
third party agrees in writing to be bound by this Section 4.14.


                                      -14-

<PAGE>




                                   ARTICLE V.
                   LEGEND REMOVAL, TRANSFER, AND CERTAIN SALES

     A.  Removal of Legend.  The Legend  shall be removed and the Company  shall
issue or cause to be issued a  certificate  without  any legend to the holder of
any Security upon which such Legend is stamped, and a certificate for a security
shall be originally issued without any legend,  if, unless otherwise required by
applicable  federal or state  securities  laws, (a) the sale of such Security is
registered  under the Securities  Act, (b) such holder provides the Company with
an opinion of counsel,  in form,  substance and scope  customary for opinions of
counsel in comparable  transactions (the reasonable cost of which shall be borne
by the  Company),  to the effect that a public sale or transfer of such Security
may be made without registration under the Securities Act, (c) such Security can
be sold  pursuant to Rule 144 and a  registered  broker  dealer  provides to the
Company's  transfer  agent  and  counsel  copies  of (i) a  "will  sell"  letter
satisfying the guidelines established by the SEC and its staff from time to time
and (ii) a customary seller's  representation letter with respect to such a sale
to be made pursuant to Rule 144 and (iii) a Form 144 in respect of such Security
executed  by such  holder and filed (or mailed for  filing)  with the SEC or (d)
such security can be sold pursuant to Rule 144(k). Each Purchaser agrees to sell
all Securities,  including those represented by a certificate(s)  from which the
Legend has been removed,  or which were  originally  issued  without the Legend,
pursuant to an effective  registration  statement and to deliver a prospectus in
connection  with  such  sale  or  in  compliance  with  an  exemption  from  the
registration  requirements  of the  Securities  Act.  In the event the Legend is
removed  from any  Security  or any  Security  is issued  without the Legend and
thereafter the effectiveness of a registration  statement covering the resale of
such  Security is  suspended  or the Company  determines  that a  supplement  or
amendment  thereto  is  required  by  applicable   securities  laws,  then  upon
reasonable  advance notice to Purchaser  holding such Security,  the Company may
require that the Legend be placed on any such  Security that cannot then be sold
pursuant to an  effective  registration  statement  or with respect to which the
opinion referred to in clause (b) next above has not been rendered, which Legend
shall be  removed  when  such  Security  may be sold  pursuant  to an  effective
registration  statement or such holder provides the opinion with respect thereto
described in clause (b) next above.

     B. Transfer  Agent  Instructions.  The Company shall  instruct its transfer
agent to issue  certificates,  registered  in the name of each  Purchaser or its
nominee,  for the  Conversion  Shares  and  Warrant  Shares in such  amounts  as
specified  from  time to time by such  Purchaser  to the  Company  upon,  and in
accordance  with, the conversion of the Preferred  Stock and the exercise of the
Warrants.  Such certificates  shall bear a legend only in the form of the Legend
and only to the extent  permitted by Section 5.1 above.  The Company agrees that
no  instruction  other than such  instructions  referred to in this Article V or
otherwise  contemplated  by this  Agreement,  and no stop transfer  instructions
other than stop transfer  instructions to give effect to Section 2.6 and Section
2.7 hereof in the case of the  Conversion  Shares prior to  registration  of the
Conversion  Shares under the Securities Act, will be given by the Company to its
transfer agent with respect to the Preferred Stock, the Warrants, the Conversion
Shares or the Warrant Shares.  Nothing in this Section shall affect in any way a
Purchaser's  obligations and agreement set forth in Section 5.1 hereof to resell
the Securities pursuant to an effective  registration statement and to deliver a
prospectus in connection with such sale or in

                                      -15-

<PAGE>



compliance  with an exemption from the  registration  requirements of applicable
securities  laws.  Without  limiting the  foregoing,  but subject to Section 5.1
above, if (a) a Purchaser provides the Company with an opinion of counsel, which
opinion of counsel shall be in form,  substance and scope customary for opinions
of counsel in comparable  transactions  (the  reasonable  cost of which shall be
borne  by the  Company),  to the  effect  that  the  Securities  to be  sold  or
transferred   may  be  sold  or  transferred   pursuant  to  an  exemption  from
registration or (b) a Purchaser transfers Securities to an affiliate or pursuant
to Rule 144,  the Company  shall  permit the  transfer,  and, in the case of the
Conversion  Shares,  promptly  instruct its transfer  agent to issue one or more
certificates  in  such  name  and in  such  denomination  as  specified  by such
Purchaser in order to effect such a transfer or sale.  The Company  acknowledges
that a breach by it of its obligations  hereunder will cause irreparable harm to
a Purchaser by vitiating the intent and purpose of the transaction  contemplated
hereby.  Accordingly,  the  Company  acknowledges  that the  remedy at law for a
breach of its obligations under this Article V will be inadequate and agrees, in
the event of a breach or threatened  breach by the Company of the  provisions of
this  Article V, that a Purchaser  shall be  entitled,  in addition to all other
available  remedies,  to an  injunction  restraining  any breach  and  requiring
immediate issuance and transfer,  without the necessity of showing economic loss
and without any bond or other security being required.

                                   ARTICLE VI.
                 CONDITIONS TO THE COMPANY'S OBLIGATION TO SELL

     A.  Conditions to the Company's  Obligation to Sell.  The obligation of the
Company hereunder to issue and sell the Convertible Securities to a Purchaser at
each Closing is subject to the satisfaction,  as of the date of each Closing and
with respect to such  Purchaser,  of each of the following  conditions  thereto,
provided that these  conditions  are for the  Company's  sole benefit and may be
waived by the Company at any time in its sole discretion:

          a. Such  Purchaser  shall have  executed  the  signature  page to this
     Agreement and the  Registration  Rights Agreement and delivered the same to
     the Company.

          b. Such Purchaser shall deliver the applicable  Purchase Price for the
     Convertible Securities purchased at the Closing.

          c. The  representations and warranties of such Purchaser shall be true
     and  correct as of the date when made and as of the  Closing as though made
     at that time,  and such  Purchaser  shall  have  performed,  satisfied  and
     complied  in all  material  respects  with  the  covenants  and  agreements
     required  by  this  Agreement  to be  performed  or  complied  with by such
     Purchaser at or prior to the Closing.

          d. No statute,  rule,  regulation,  executive order, decree, ruling or
     injunction shall have been enacted, entered, promulgated or endorsed by any
     court  or   governmental   authority  of  competent   jurisdiction  or  any
     self-regulatory organization having authority over the matters contemplated
     hereby  which  restricts  or  prohibits  the  consummation  of  any  of the
     transactions contemplated by this Agreement.

                                                       -16-

<PAGE>



          e. The aggregate purchase price paid to the Company for the Securities
     purchased  pursuant  to the First  Closing  shall be Five  Million  Dollars
     ($5,000,000), and the aggregate purchase price for the Securities purchased
     at the second closing shall be Three Million Dollars ($3,000,000),  in both
     cases net of the  reasonable  fees and expenses of  Purchaser  reimbursable
     pursuant  to Section  4.6 hereof and net of any fees paid  directly  to the
     placement agent.

                                  ARTICLE VII.
              CONDITIONS TO EACH PURCHASER'S OBLIGATION TO PURCHASE

     A.  Conditions  to the First  Closing.  The  obligation  of each  Purchaser
hereunder to purchase the Convertible Securities and Warrants to be purchased by
it on the date of the First  Closing is subject to the  satisfaction  of each of
the  following   conditions,   provided  that  these  conditions  are  for  each
Purchaser's  sole benefit and may be waived by such  Purchaser  (with respect to
it) at any time in such Purchaser's sole discretion:

          a.  The  Company  shall  have  executed  the  signature  page  to this
     Agreement and the  Registration  Rights Agreement and delivered the same to
     Purchaser.

          b. The Company shall have delivered duly executed certificates for the
     Preferred  Stock and Warrants  (in such  denominations  as Purchaser  shall
     request) being so purchased by Purchaser at the Closing.

          c. The  Company  shall have  delivered  copies of  resolutions  of the
     Company's board of directors, a certificate of the Company's secretary, and
     any other documents or  certificates  evidencing  corporate  proceedings as
     required by Purchaser, all in form reasonably satisfactory to Purchaser.

          d. The Company  shall have  reserved for issuance at least ten million
     (10,000,000)  shares  of  Common  Stock  issuable  upon  conversion  of the
     Preferred Stock and at least one million forty thousand  (1,040,000) shares
     of Common Stock issuable upon exercise of the Warrants.

          e. The Common Stock shall be listed on the Nasdaq SmallCap Market, the
     Nasdaq National Market System,  the New York Stock Exchange or the American
     Stock  Exchange  and  trading  in the  Common  Stock  shall  not have  been
     suspended by the Nasdaq SmallCap Market, the Nasdaq National Market System,
     the New York Stock  Exchange or the  American  Stock  Exchange,  the SEC or
     other regulatory  authority and the Company shall not be aware of any facts
     or  circumstances  which would reasonably cause the Company to believe that
     the Common Stock will be de-listed in the foreseeable future.

          f. The representations and warranties of the Company shall be true and
     correct as of the date when made and as of the  Closing  as though  made at
     that time and the Company

                                      -17-

<PAGE>



     shall  have  performed,  satisfied  and  complied  with the  covenants  and
     agreements  required by this  Agreement to be performed or complied with by
     the Company at or prior to the First Closing. Purchaser shall have received
     a certificate,  executed by the Chief Executive  Officer or Chief Financial
     Officer of the  Company,  dated as of the First  Closing  to the  foregoing
     effect  and as to such  other  matters as may be  reasonably  requested  by
     Purchaser. Notwithstanding the foregoing, if there shall occur any facts or
     circumstances  subsequent  to the date of this  Agreement  but prior to the
     First Closing which cause any of the  representations and warranties of the
     Company  hereunder to be untrue,  the Company  shall deliver to Purchaser a
     written notice for each Purchaser's execution, setting forth such facts and
     circumstances (the "Disclosure Notice"),  and Purchaser may, at Purchaser's
     option either (i) decline to proceed with the First Closing,  in which case
     this  Agreement  (other than  Section 4.6 hereof)  shall be deemed null and
     void and of no further force or effect,  and the Company and each Purchaser
     shall be released from all obligations and liabilities under this Agreement
     (other than the Company's  obligations  under Section 4.6 hereof),  or (ii)
     execute and deliver to the Company the  Disclosure  Notice and proceed with
     the First Closing and the consummation of the transactions  contemplated by
     this  Agreement,  in which case the  representations  and warranties of the
     Company made as of the execution  and delivery of this  Agreement and as of
     the First  Closing shall be deemed to be amended to  incorporate  the facts
     and circumstances set forth in the Disclosure Notice.

          g. No statute,  rule,  regulation,  executive order, decree, ruling or
     injunction shall have been enacted, entered, promulgated or endorsed by any
     court  or   governmental   authority  of  competent   jurisdiction  or  any
     self-regulatory organization having authority over the matters contemplated
     hereby  which  prohibits  the  consummation  of  any  of  the  transactions
     contemplated by this Agreement.

          h. Purchaser shall have received the officer's  certificate  described
     in Section 3.3, dated as of the First Closing.

          i.  Purchaser  shall have  received  on the date of the First  Closing
     opinions  of  the  Company's  outside  legal  counsel  (including,  without
     limitation,  an enforceability opinion under New York law and an opinion of
     the Company's  Nevada legal counsel opining as to Nevada law),  dated as of
     the  First  Closing  from  firms  and  in  form  and  substance  reasonably
     acceptable to Purchasers (the exact form of which shall have been delivered
     to Purchaser not later than two (2) days prior to the First Closing),  and,
     without  limitation,  containing  a so-called  10b-5  opinion,  in the form
     attached hereto as Exhibit D.

          j. The Company's  transfer agent has agreed to act in accordance  with
     irrevocable instructions in the form attached hereto as Exhibit E.

          k. The Company  shall have entered  into an agreement  with Haim Aviv,
     Ph.D.  restricting  dispositions of Common Stock beneficially owned by such
     person and in the form attached hereto as Exhibit F and shall have obtained
     a proxy therefrom in the form attached hereto as Exhibit G.


                                      -18-

<PAGE>



               l. The  Certificate of  Designation  shall have been accepted for
          filing with the  Secretary  of State of the State of Nevada and a copy
          thereof  certified by the Secretary of State of Nevada shall have been
          delivered to Purchaser.

     B.  Conditions to the Second  Closing.  The  obligation  of each  Purchaser
hereunder to purchase the Convertible Securities and Warrants to be purchased by
it on the date of the Second Closing is subject to the  satisfaction  of each of
the  following   conditions,   provided  that  these  conditions  are  for  each
Purchaser's  sole benefit and may be waived by such  Purchaser  (with respect to
it) at any time in such Purchaser's sole discretion:

          a.  The  Company  shall  have  executed  the  signature  page  to this
     Agreement and the  Registration  Rights Agreement and delivered the same to
     Purchaser.

          b. The Company shall have delivered duly executed certificates for the
     Preferred  Stock and Warrants  (in such  denominations  as Purchaser  shall
     request) being so purchased by Purchaser at the Closing.

          c. The  Company  shall have  delivered  copies of  resolutions  of the
     Company's board of directors, a certificate of the Company's secretary, and
     any other documents or  certificates  evidencing  corporate  proceedings as
     required by Purchaser, all in form reasonably satisfactory to Purchaser.

          d. The Company shall have registered under the Registration  Statement
     the  greater of (A) two hundred  percent  (200%) of the number of shares of
     Common  Stock  issuable  upon  conversion  of the  Preferred  Stock and the
     exercise of the Warrants, or (B) 11,040,000 shares of Common Stock.

          e. The Company shall have reserved for issuance the greater of (A) two
     hundred  percent  (200%) of the number of shares of Common  Stock  issuable
     upon conversion of the Preferred Stock and the exercise of the Warrants, or
     (B) 11,040,000 shares of Common Stock.

          f. The Common Stock shall be listed on the Nasdaq SmallCap Market, the
     Nasdaq National Market System,  the New York Stock Exchange or the American
     Stock  Exchange  and  trading  in the  Common  Stock  shall  not have  been
     suspended by the Nasdaq SmallCap Market, the Nasdaq National Market System,
     the New York Stock  Exchange or the  American  Stock  Exchange,  the SEC or
     other regulatory  authority and the Company shall not be aware of any facts
     or  circumstances  which would reasonably cause the Company to believe that
     the Common Stock would be delisted in the foreseeable future.

          g. The representations and warranties of the Company shall be true and
     correct  as of the date when made and as of the  Second  Closing  as though
     made at that time and the  Company  shall  have  performed,  satisfied  and
     complied with the covenants and agreements required by this Agreement to be
     performed  or  complied  with by the  Company  at or  prior  to the  Second
     Closing. Purchaser shall have received a certificate, executed by the Chief
     Executive Officer or

                                      -19-

<PAGE>



     Chief Financial  Officer of the Company,  dated as of the Second Closing to
     the  foregoing  effect  and as to such other  matters as may be  reasonably
     requested by Purchaser. Notwithstanding the foregoing, if there shall occur
     any facts or  circumstances  subsequent  to the date of this  Agreement but
     prior to the Second  Closing  which  cause any of the  representations  and
     warranties of the Company hereunder to be untrue, the Company shall deliver
     to Purchaser a written notice for each Purchaser's execution, setting forth
     such facts and circumstances (the "Disclosure Notice"),  and Purchaser may,
     at  Purchaser's  option  either  (i)  decline  to  proceed  with the Second
     Closing,  in which case the  Company and each  Purchaser  shall be released
     from all obligations and liabilities under this Agreement to consummate the
     Second  Closing  (other than the  Company's  obligations  under Section 4.6
     hereof),  or (ii) execute and deliver to the Company the Disclosure  Notice
     and  proceed  with  the  Second  Closing  and  the   consummation   of  the
     transactions   contemplated   by  this   Agreement,   in  which   case  the
     representations  and warranties of the Company made as of the execution and
     delivery of this  Agreement and as of the Second Closing shall be deemed to
     be  amended to  incorporate  the facts and  circumstances  set forth in the
     Disclosure Notice.

          h. No statute,  rule,  regulation,  executive order, decree, ruling or
     injunction shall have been enacted, entered, promulgated or endorsed by any
     court  or   governmental   authority  of  competent   jurisdiction  or  any
     self-regulatory organization having authority over the matters contemplated
     hereby  which  prohibits  the  consummation  of  any  of  the  transactions
     contemplated by this Agreement.

          i. Purchaser shall have received the officer's  certificate  described
     in Section 3.3, effective as of the Closing.

          j.  Purchaser  shall have  received on the date of the Second  Closing
     opinions  of  the  Company's  outside  legal  counsel  (including,  without
     limitation,  an enforceability opinion under New York law and an opinion of
     the Company's  Nevada legal counsel opining as to Nevada law),  dated as of
     the  Second  Closing,  from  firms  and in form  and  substance  reasonably
     acceptable to Purchasers (the exact form of which shall have been delivered
     to  Purchaser  not later than two (2) days  prior to the  Second  Closing),
     including  without  limitation,  a  so-called  10b-5  opinion,  in the form
     attached hereto as Exhibit D.

          k. The Company's  transfer agent has agreed to act in accordance  with
     irrevocable instructions in the form attached hereto as Exhibit E.

          l. The agreements  with Haim Aviv,  Ph.D.  Stock in the forms attached
     hereto as Exhibit F and Exhibit G shall continue to be effect.

          m. The Certificate of Designation  shall have been accepted for filing
     with the  Secretary  of State of the  State of  Nevada  and a copy  thereof
     certified by the Secretary of State of Nevada shall have been  delivered to
     Purchaser.


                                      -20-

<PAGE>



          n. The average of Closing Bid Prices for the Common  Stock  during the
     ten consecutive  trading day period  immediately  preceding the date of the
     Second Closing shall not have been less than Two Dollars ($2.00) per share.

          o. A registration  statement  covering the  Conversion  Shares and the
     Warrant Shares shall have been filed and declared  effective by the SEC and
     available for resales.

          p. The Company  shall,  if required by the terms of this Agreement and
     the Certificate of Designation,  have received  Shareholder Approval as set
     forth in Section 4.13 hereof.

          q. The Company  shall have  received FDA approval of the NDA submitted
     for the drug Lotemax.

                                  ARTICLE VIII.
                          GOVERNING LAW; MISCELLANEOUS

     A. Governing  Law;  Jurisdiction.  This Agreement  shall be governed by and
construed in  accordance  with the laws of the State of New York  applicable  to
contracts  made and to be performed in the State of New York. The parties hereto
irrevocably  consent to the  jurisdiction  of the United States  federal  courts
located in the State of New York and the state  courts  located in the County of
New York in the State of New York in any suit or proceeding  based on or arising
under this Agreement or the  transactions  contemplated  hereby and  irrevocably
agree that all claims in respect of such suit or proceeding may be determined in
such courts. The parties  irrevocably waive the defense of an inconvenient forum
to the  maintenance of such suit or  proceeding.  Each party further agrees that
service of process  upon any other party to this  Agreement  mailed by the first
class mail shall be deemed in every  respect  effective  service of process upon
such party in any suit or proceeding  arising  hereunder.  Nothing  herein shall
affect the right of any party to serve process in any other manner  permitted by
law. The parties hereto agree that a final  non-appealable  judgment in any such
suit  or  proceeding   shall  be  conclusive   and  may  be  enforced  in  other
jurisdictions by suit on such judgment or in any other lawful manner.

     B.   Counterparts.   This   Agreement  may  be  executed  in  two  or  more
counterparts,  including, without limitation, by facsimile transmission,  all of
which  counterparts  shall be  considered  one and the same  agreement and shall
become effective when  counterparts have been signed by each party and delivered
to the other party.  In the event any  signature  page is delivered by facsimile
transmission,  the party  using such means of delivery  shall  cause  additional
original executed signature pages to be delivered to the other parties.

     C.  Headings.  The  headings  of  this  Agreement  are for  convenience  of
reference  and shall not form part of, or affect  the  interpretation  of,  this
Agreement.

     D.  Severability.  If any provision of this  Agreement  shall be invalid or
unenforceable in any jurisdiction, such invalidity or unenforceability shall not
affect the validity or enforceability of

                                      -21-

<PAGE>



the  remainder  of this  Agreement  or the  validity or  enforceability  of this
Agreement in any other jurisdiction.

     E. Scope of Agreement; Amendments. Except as specifically set forth herein,
no Purchaser makes any  representation,  warranty,  covenant or undertaking with
respect to the transactions  contemplated hereby. No provision of this Agreement
may be waived other than by an instrument  in writing  signed by the party to be
charged with enforcement and no provision of this Agreement may be amended other
than by an instrument in writing signed by the Company and each Purchaser.

     F. Notice.  Any notice herein required or permitted to be given shall be in
writing  and  may  be   personally   served  or   delivered  by  courier  or  by
facsimile-machine  confirmed telecopy, and shall be deemed delivered at the time
and date of receipt (which shall include telephone line facsimile transmission).
The addresses for such communications shall be:

                           If to the Company:

                           Pharmos Corporation
                           33 Wood Avenue South
                           Suite 466
                           Iselin, New Jersey 08830
                           Telecopy: (732) 603-3532
                           Attention: President

                           with a copy to:

                           Ehrenreich, Eilenberg, Krause & Zivian, LLP
                           11 East 44th Street, 17th Floor
                           New York, New York 10017
                           Telecopy: (212) 986-2399
                           Attention: Adam D. Eilenberg, Esq.

                           If to CC Investments, LDC:

                           CC Investments, LDC
                           Corporate Centre, West Bay Road
                           P.O. Box 31106 SMB
                           Grand Cayman, Cayman Islands


                                      -22-

<PAGE>



                           with a copy to:

                           Castle Creek Partners, LLC
                           333 West Wacker Drive
                           Suite 1410
                           Chicago, IL  60606
                           Telecopy:  (312) 435-2636
                           Attention: Portfolio Manager

                           and with a copy to:

                           Altheimer & Gray
                           10 South Wacker Drive
                           Suite 4000
                           Chicago, IL  60606
                           Telecopy:  (312) 715-4800
                           Attention: Peter H. Lieberman, Esq.

If to any other Purchaser, to such address set forth under such Purchaser's name
on the  signature  page  hereto  executed  by such  Purchaser.  Each party shall
provide notice to the other parties of any change in address.

     G.  Successors and Assigns.  This Agreement shall be binding upon and inure
to the benefit of the  parties and their  successors  and  assigns.  Neither the
Company  nor  any  Purchaser  shall  assign  this  Agreement  or any  rights  or
obligations   hereunder   without  the  prior  written  consent  of  the  other.
Notwithstanding  the  foregoing,  each  Purchaser  may  assign  its  rights  and
obligations  hereunder to any of its "affiliates," as that term is defined under
the Exchange Act,  without the consent of the Company so long as such  affiliate
is an accredited investor. This provision shall not limit each Purchaser's right
to transfer the Securities pursuant to the terms of this Agreement. In addition,
and  notwithstanding  anything to the contrary contained in this Agreement,  the
Certificate of Designation,  the Warrants or the Registration  Rights Agreement,
the Securities may be pledged,  and all rights of Purchaser under this Agreement
or any other  agreement  or  document  related to the  transaction  contemplated
hereby may be assigned,  without further consent of the Company,  to a bona fide
pledgee in connection with a Purchaser's margin or brokerage accounts.

     H. Third Party Beneficiaries. This Agreement is intended for the benefit of
the parties hereto and their respective  permitted successors and assigns and is
not for the benefit of, nor may any  provision  hereof be enforced by, any other
person.

     I.  Survival.  The  representations  and  warranties of the Company and the
agreements and covenants set forth in Articles III, IV, V and VIII shall survive
the closing hereunder  notwithstanding any due diligence investigation conducted
by or on behalf of Purchaser;  provided,  however,  that the representations and
warranties  with respect to the Preferred  Stock shall  terminate if a claim for
the breach  thereof is not  asserted on or before the first  anniversary  of the
date on which all of the

                                      -23-

<PAGE>



Preferred  Stock has been  converted or has been redeemed by the Company and all
other representations and warranties shall terminate on the earlier of the fifth
anniversary  of the First Closing and the date on which all of the Warrants have
been  exercised  in  full;  provided,  however,  that  the  representations  and
warranties  set forth in Sections  3.9,  3.10 and 3.15 shall not  terminate  but
shall continue indefinitely.

     J.  Indemnification.  In  consideration  of the  Purchaser's  execution and
delivery of this  Agreement and acquiring the Preferred  Shares,  the Conversion
Shares,  the Warrants and the Warrant Shares hereunder and in addition to all of
the Company's other obligations under this Agreement,  the Company shall defend,
protect,  indemnify and hold harmless the Purchaser and each other holder of the
Preferred Stock, the Conversion  Shares, the Warrants and the Warrant Shares and
all of their  officers,  directors,  employees  and agents  (including,  without
limitation,  those retained in connection with the transactions  contemplated by
this Agreement)  (collectively,  the "Indemnitees") from and against any and all
actions,  causes of action,  suits,  claims,  losses,  costs,  penalties,  fees,
liabilities and damages, and expenses in connection  therewith  (irrespective of
whether any such  Indemnitee is a party to the action for which  indemnification
hereunder is sought), and including reasonable attorneys' fees and disbursements
(the  "Indemnified  Liabilities"),  incurred by an Indemnitee as a result of, or
arising  out of,  or  relating  to (a) any  misrepresentation  or  breach of any
representation  or  warranty  made  by  the  Company  in  this  Agreement,   the
Certificate of Designation, the Warrants or the Registration Rights Agreement or
any other certificate,  instrument or document  contemplated  hereby or thereby,
(b) any breach of any covenant, agreement or obligation of the Company contained
in  this  Agreement,  the  Certificate  of  Designation,  the  Warrants  or  the
Registration  Rights Agreement or any other certificate,  instrument or document
contemplated  hereby  or  thereby,  or (c) any  cause of  action,  suit or claim
brought or made against such Indemnitee and arising out of or resulting from the
execution,  delivery,  performance or enforcement of this Agreement or any other
instrument,  document  or  agreement  executed  pursuant  hereto  by  any of the
Indemnitees,  any  transaction  financed  or to be financed in whole or in part,
directly or indirectly, with the proceeds of the issuance of the Preferred Stock
or the status of Purchaser or any holder of the Preferred  Stock, the Conversion
Shares,  the Warrants or the Warrant Shares as an investor in the Company except
for any such Indemnified  Liabilities  which directly and primarily results from
such  Indemnitee's  (i)  gross  negligence  and  willful   misconduct  and  (ii)
intentional  or  grossly  negligent  breach  by  such  Indemnitee  of any of its
covenants  herein.  To the extent that the foregoing  undertaking by the Company
may be  unenforceable  for any  reason,  the  Company  shall  make  the  maximum
contribution  to the  payment  and  satisfaction  to  each  of  the  Indemnified
Liabilities which is permissible under applicable law.

     K. Public  Filings;  Publicity.  Immediately  following  execution  of this
Agreement,  the Company shall issue a press  release,  which shall be subject to
the  prior  review  and  approval  of  the  Purchasers,   with  respect  to  the
transactions  contemplated  hereby.  Prior to the  expiration  of ten (10)  days
following  the date of the First  Closing,  the  Company  shall  file a Form 8-K
regarding the transaction  contemplated  by this Agreement;  such Form 8-K shall
have as exhibits thereto the material documents executed in connection with this
transaction  contemplated  hereby. The Company and each Purchaser shall have the
right to approve  before  issuance any press  releases  (including the foregoing
press release), SEC or other filings, or any other public statements, with

                                      -24-

<PAGE>



respect to the transactions  contemplated hereby;  provided,  however,  that the
Company shall be entitled,  without the prior approval of any Purchaser, to make
any press release or SEC, NASDAQ,  NASD or exchange filings with respect to such
transactions  as is required by applicable  law and  regulations  (although each
Purchaser  shall (to the extent  time  permits) be  consulted  by the Company in
connection  with any  such  press  release  prior to its  release  and  shall be
provided with a copy thereof).

     L. Further Assurances. Each party shall do and perform, or cause to be done
and performed,  all such further acts and things,  and shall execute and deliver
all such other agreements, certificates, instruments and documents, as the other
party may reasonably request in order to carry out the intent and accomplish the
purposes of this Agreement and the consummation of the transactions contemplated
hereby.

     M. Remedies.  No provision of this Agreement  providing for any remedy to a
Purchaser  shall limit any remedy  which would  otherwise  be  available to such
Purchaser at law or in equity.  Nothing in this Agreement shall limit any rights
a Purchaser may have with any applicable  federal or state  securities laws with
respect to the investment contemplated hereby.

     N. Termination. In the event that the First Closing shall not have occurred
within  forty-eight  (48) hours of the execution of this  Agreement,  unless the
parties agree otherwise, this Agreement shall terminate.


                                      * * *


                                      -25-

<PAGE>


     IN WITNESS WHEREOF, the undersigned  Purchasers and the Company have caused
this Agreement to be duly executed as of the date first above written.

                                   PURCHASER:

                                   CC INVESTMENTS, LDC



                                   By: ______________________________________
                                        Its: ________________________________


                                   AGGREGATE NUMBER OF
                                   PREFERRED SHARES: 500


                                   COMPANY:

                                   PHARMOS CORPORATION



                                   By: ____________________________________
                                        Its: ______________________________






                                 


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