PHARMOS CORP
S-3/A, 1998-07-14
PHARMACEUTICAL PREPARATIONS
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      As filed with the Securities and Exchange Commission on July 14, 1998
    

                                                      Registration No. 333-47359
- --------------------------------------------------------------------------------


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                      ------------------------------------

   
                                 AMENDMENT NO. 3
                                       TO
                                    FORM S-3
                             REGISTRATION STATEMENT
                  UNDER THE SECURITIES ACT OF 1933, AS AMENDED
    

                      ------------------------------------


                               PHARMOS CORPORATION
             (Exact name of registrant as specified in its charter)

              Nevada                                    36-3207413
   (State or other jurisdiction             (I.R.S. Employer Identification No.)
of incorporation or organization)

                         33 Wood Avenue South, Suite 466
                            Iselin, New Jersey 08830
                                 (732) 603-3526
               (Address, including zip code, and telephone number,
                 including area code, of registrant's principal
                               executive offices)

                      ------------------------------------


                                 GAD RIESENFELD
                         33 Wood Avenue South, Suite 466
                            Iselin, New Jersey 08830
                                 (732) 603-3526
                (Name, address, including zip code, and telephone
               number, including area code, of agent for service)

                      ------------------------------------


                                   Copies to:
                             ADAM D. EILENBERG, ESQ.
                    Ehrenreich Eilenberg Krause & Zivian LLP
                         11 East 44th Street, 17th Floor
                            New York, New York 10017

                      ------------------------------------


     Approximate  date of  commencement  of proposed sale to public:  As soon as
practicable after the effective date of the registration statement

     If the only  securities  being  registered  on this Form are being  offered
pursuant to dividend or interest  reinvestment plans, please check the following
box. | |

     If any of the securities being registered on this Form are to be offered on
a delayed or continuous  basis  pursuant to Rule 415 under the Securities Act of
1933,  other than  securities  offered in  connection  with dividend or interest
reinvestment plans, check the following box. | X |


<PAGE>

   
                                         CALCULATION OF REGISTRATION FEE
<TABLE>
<CAPTION>
                                                        Proposed           Proposed                              
                                                        Maximum            Maximum            Amount of
Title of Each Class of               Amount to be       Offering Price     Aggregate          Registration
Securities to be Registered          Registered         Per Unit           Price              Fee
- -----------------------------------  -----------------  -----------------  -----------------  ----------------
<S>                                    <C>                  <C>            <C>                   <C>   
Shares of Common Stock to be           6,000,000(1)(2)      $2.53(3)       $15,180,000           $4,554
sold by Selling Security holder                                            
                                                                           
Warrants to Purchase 500,000             500,000                -(4)                 -(4)             -(4)
Shares of Common Stock at                                                  
$2.67 per share                                                            
                                                                           
Shares of Common Stock                   500,000(2)         $2.67           $1,335,000             $394
issuable upon exercise of                                                  
Warrants to purchase 500,000                                               
Shares at $2.67 per share                                                  
                                                                           
Warrants to Purchase 150,000             150,000                -(4)                 -(4)             -(4)
Shares of Common Stock at                                                  
$2.28 per share                                                            
                                                                           
Shares of Common Stock                   150,000(2)         $2.28             $342,000             $101
issuable upon exercise of                                                  
Warrants to purchase 150,000                                               
Shares at $2.28 per share                                                  
                                                                           
Warrants to Purchase 171,052             171,052                -(4)                 -(4)             -(4)
Shares of Common Stock at                                                  
$2.28 per share                                                            
                                                                           
Shares of Common Stock                   171,052(2)         $1.38             $236,052              $70
issuable upon exercise of                                                  
Warrants to purchase 171,052                                               
Shares at $1.38 per share                                                  
Total Registration Fee                                                     $17,093,052           $5,119
</TABLE>                                                                   
                                                                        
(1)  Assumes  conversion  price for all the preferred  stock at $0.83,  which is
     estimated for the purpose of  determining  the maximum  number of shares of
     Common Stock obtained upon conversion.

(2)  Pursuant to Rule 416 under the  Securities  Act of 1933,  an  indeterminate
     number of  additional  shares of Common Stock as may become  issuable  upon
     conversion  of the  Series  C  Preferred  Stock  and  the  exercise  of the
     Warrants,  in accordance with their  respective  terms, to prevent dilution
     resulting from stock splits, stock dividends or similar transactions.

(3)  Estimated  solely for the  purpose of  calculating  the  registration  fee.
     Proposed  maximum  offering  price per share is  estimated  based  upon the
     closing price of the Company's  Common Stock listed on the Nasdaq  SmallCap
     Market on July 7, 1998.

(4)  The  warrants  were  issued  in  connection  with  the  Private   Placement
     Transaction  and the 1997 Private  Placement  Transaction for no additional
     consideration  and therefore  there is no  applicable  offering  price,  no
     maximum offering price and no fee.
    


<PAGE>




     The  registrant  hereby amends the  registration  statement on such date or
dates as may be necessary to delay its effective date until the registrant shall
file a further  amendment  which  specifically  states  that  this  registration
statement shall  thereafter  become effective in accordance with Section 8(a) of
the  Securities  Act of 1933 or until the  registration  statement  shall become
effective on such date as the Commission,  acting pursuant to said Section 8(a),
may determine.


<PAGE>



                               PHARMOS CORPORATION

Cross  Reference  Sheet Showing  Location in Prospectus of Information  Required
Therein by Item 1 through 13 of Form S-3

<TABLE>
<CAPTION>
      Registration Statement                                            Prospectus Caption
          Item and Heading                                                  of Location    
          ----------------                                                  -----------    
<S>                                                                    <C>
  1.  Forepart of the Registration
      Statement and Outside Front
      Cover Page of Prospectus ........................................Outside Front Cover

  2.  Inside Front and Outside Back
      Cover Pages and Prospectus.......................................Inside Front Cover Page

  3.  Summary Information,
      Prospectus Summary
      and Ratio of Earnings to                                         Outside Front Cover,
      Fixed Charges....................................................Risk Factors

  4.  Use of Proceeds..................................................Use of Proceeds

  5.  Determination of Offering Price..................................Cover Page

  6.  Dilution.........................................................Dilution

  7.  Selling Security Holder..........................................Selling Security Holder

  8.  Plan of Distribution.............................................Cover Page, Plan of Distribution

  9.  Description of the Securities to
      be Registered....................................................Description of Securities

 10.  Interest of Named Experts and Counsel............................Experts

 11.  Material Changes.................................................Recent Developments

 12.  Incorporation of Certain
      Information by Reference.........................................Incorporation of Certain
                                                                       Documents by Reference

 13.  Disclosure of Commission Position
      on Indemnification for Securities
      Act Liabilities..................................................Commission's Policy on
                                                                       Indemnification for Securities Act
                                                                       Liabilities
</TABLE>


<PAGE>



                               PHARMOS CORPORATION
                               -------------------

                                   PROSPECTUS


   
     This Prospectus relates to and covers the offer and sale by certain persons
listed under "Selling Stockholders (collectively, the "Selling Stockholders") of
an aggregate of up to (a) 6,000,000  shares (the "Shares") of common stock,  par
value $.03 per share (the "Common Stock") of Pharmos Corporation (the "Company")
issuable  upon  the   conversion  of  the  Company's  5%  Series  C  Convertible
Participating  Preferred  Stock (the  "Series C  Preferred  Stock")  issued in a
private transaction in February 1998 (the "Private Placement Transaction"),  (b)
500,000  shares of Common Stock  issuable  upon  exercise of warrants held by CC
Investments,  LDC which are exercisable at $2.67 per share from February 3, 1999
to February 4, 2004,  (c) 150,000  shares of Common Stock issuable upon exercise
of warrants to purchase  such shares at an exercise  price of $2.28 per share by
Gemini Capital issued in connection  with such company's role as placement agent
for the Private  Placement  Transaction  (which  warrants are  exercisable  from
February 3, 1999 until  January 20,  2003),  (d) 171,052  shares of Common Stock
issuable upon exercise of warrants to purchase such shares at an exercise  price
of $1.38 per share by Alan Mark issued in connection  with his role as placement
agent for a private  placement  transaction  completed  in March 1997 (the "1997
Private Placement  Transaction") (which warrants are exercisible until March 31,
2008) (all such warrants  collectively,  the "Warrants" and the shares of Common
Stock  issuable  upon the  exercise of the Warrants  collectively,  the "Warrant
Shares"), (e) offer and sale of the Warrants and (f) in accordance with Rule 416
under the  Securities  Act of 1933,  as  amended  (the  "Act"),  such  presently
indeterminate  number of  additional  shares of Common  Stock as may be issuable
upon  conversion of the Series C Preferred Stock and exercise of the Warrants as
a result of stock splits, stock dividends and other antidilution provisions. See
"Selling  Stockholders" and "Plan of Distribution." The Company will not receive
any proceeds  from the sale of Common  Stock.  The Company has agreed to pay the
expenses of  registration  of the Common Stock,  including  legal and accounting
fees.  The Selling  Stockholders  currently hold 5,000 shares Series C Preferred
Stock.

     Each  share of Series C  Preferred  Stock is  convertible  into a number of
shares of Common Stock equal to (i) $1,000 (ii)  divided by a  conversion  price
which is  currently  90% of the  average  of the low trade  prices of the Common
Stock  for the five (5)  consecutive  trading  days  ending on the  trading  day
immediately  preceding the conversion date (the "Variable Conversion Price") and
on and after  August 2, 1998 the lesser of the Variable  Conversion  Price and a
number  of  shares  of  Common  Stock  equal to (i)  $1,000  (ii)  divided  by a
conversion  price which is one hundred  twenty  percent (120%) of the average of
the closing bid prices of the Common  Stock for the trading  days  beginning  on
July 4,  1998 and  ending on August 2,  1998.  Under the  applicable  conversion
formulas of the Series C Preferred  Stock,  the number of shares of Common Stock
("Common  Shares")  issuable upon  conversion is inversely  proportional  to the
market price of the Common Shares at the time of conversion (i.e., the number of
shares increases as the market price of the Common Shares decreases); and except
with  respect  to  certain  redemption  rights of the  Company  for the Series C
Preferred Stock and the limitation under Nasdaq SmallCap regulations which limit
the aggregate  amount of Common Shares which the Company may issue at a discount
from market price upon  conversion of the Series C Preferred  Stock and Warrants
without stockholder approval,  (which stockholder approval is being requested by
the Company), there is no cap on the
    


<PAGE>



number of shares of Common Stock which may be issued. In addition, the number of
Common Shares  issuable upon the conversion of the Series C Preferred  Stock and
the exercise of Warrants is subject to adjustment upon the occurrence of certain
dilutive events.

     The  shares of  Common  Stock  offered  hereby  may be sold by the  Selling
Stockholders or by pledgees, donees, transferees or other successors in interest
that receive such shares as a gift,  partnership  distribution or other non-sale
related  transfer.  The shares of Common  Stock may be sold from time to time in
transactions in the over-the-counter  market, in negotiated  transactions,  or a
combination  of such methods of sale,  at fixed prices which may be changed,  at
market prices  prevailing  at the time of sale, at prices  related to prevailing
market prices or at negotiated prices. The Selling  Stockholders may effect such
transactions by selling the Common Stock to or through broker-dealers, including
block  trades in which  brokers or dealers will attempt to sell the Common Stock
as agent but may position and resell the block as  principal,  or in one or more
underwritten  offerings on a firm  commitment or best efforts basis.  For a more
complete description of the manner in which Common Stock may be offered and sold
pursuant hereto see "Plan of Distribution."

     In  connection  with this  offering,  the Selling  Stockholder  and certain
holders of the Warrants who may be deemed to be "affiliates" of the Company,  as
that term is defined  under the Act,  may be deemed to be an  "underwriter,"  as
that term is defined  under the Act,  of the Shares or  Warrant  Shares  offered
hereby.  It is  anticipated  that the Selling  Stockholder  and such  affiliates
intend to sell the Shares or Warrant Shares offered hereby from time to time for
their  own  respective  accounts  in the open  market at the  prices  prevailing
therein or in  individually  negotiated  transactions  at such  prices as may be
agreed upon. Each Selling  Stockholder and such affiliate will bear all expenses
with respect to the offering of the Shares or Warrant  Shares  offered hereby by
him except the costs of legal counsel and costs associated with registering such
shares under the Act and preparing and printing this Prospectus.

     The net proceeds from Shares to be sold by the Selling  Stockholder (and by
holders of Warrant  Shares who exercise  their  Warrants) will inure entirely to
their benefit and not to that of the Company;  however, the Company will receive
proceeds from the exercise of the Warrants.

   
     The Company's Common Stock is traded on the over-the-counter  market and is
quoted on the Nasdaq SmallCap Market under the symbol "PARS".  The closing price
of the Company's Common Stock on July 7, 1998 was $2.53.
    



THESE  SECURITIES  INVOLVE A HIGH  DEGREE OF RISK AND  SUBSTANTIAL  DILUTION  AS
DESCRIBED HEREIN (SEE "RISK FACTORS" AND "DILUTION").

THESE  SECURITIES  HAVE NOT BEEN APPROVED OR  DISAPPROVED  BY THE SECURITIES AND
EXCHANGE  COMMISSION OR ANY STATE  SECURITIES  COMMISSION NOR HAS THE SECURITIES
AND  EXCHANGE  COMMISSION  OR ANY STATE  SECURITIES  COMMISSION  PASSED UPON THE
ACCURACY OR ADEQUACY


<PAGE>



OF THIS PROSPECTUS.  ANY REPRESENTATION TO THE CONTRARY IS A
CRIMINAL OFFENSE.


            The date of this Prospectus is _________________________



     The  Company  will  furnish  to each  person  to whom  this  Prospectus  is
delivered,  upon written request, a copy of any or all of the documents referred
to by reference,  other than exhibits to such documents unless such exhibits are
specifically incorporated herein by reference.  Requests should be addressed to:
Mr. Gad Riesenfeld,  President and Chief Operating Officer, Pharmos Corporation,
33 Wood Avenue South, Suite 466, Iselin, New Jersey 08830.


     NO  DEALER,  SALESMAN  OR  OTHER  PERSON  HAS BEEN  AUTHORIZED  TO GIVE ANY
INFORMATION  OR TO MAKE ANY  REPRESENTATION  OTHER THAN THOSE  CONTAINED IN THIS
PROSPECTUS.  ANY INFORMATION OR REPRESENTATION NOT HEREIN CONTAINED, IF GIVEN OR
MADE,  MUST NOT BE RELIED UPON AS HAVING BEEN  AUTHORIZED  BY THE COMPANY.  THIS
PROSPECTUS  DOES NOT  CONSTITUTE  AN OFFER OR  SOLICITATION  IN  RESPECT  OF THE
SECURITIES  IN ANY  JURISDICTION  IN WHICH SUCH OFFER OR  SOLICITATION  WOULD BE
UNLAWFUL. DELIVERY OF THIS PROSPECTUS SHALL NOT, UNDER ANY CIRCUMSTANCES, CREATE
ANY  IMPLICATION  THAT THERE HAS BEEN NO CHANGE IN THE  AFFAIRS  OF THE  COMPANY
SINCE THE DATE OF THIS PROSPECTUS.


<PAGE>



                             ADDITIONAL INFORMATION

     The Company has filed with the  Securities  and  Exchange  Commission,  450
Fifth Street, Washington, D.C. 20549, a Registration Statement on Form S-3 under
the Securities Act of 1933 with respect to the securities  offered hereby.  This
Prospectus filed as part of such Registration Statement does not contain all the
information set forth in, or annexed as exhibits to, the Registration Statement.
For further  information  pertaining to the  securities  offered  hereby and the
Company,  reference  is  made to the  Registration  Statement  and the  exhibits
thereto. The Registration Statement and exhibits thereto may be inspected at the
Headquarters  Office of the  Securities and Exchange  Commission  located at 450
Fifth Street,  N.W.,  Room 1024,  Washington,  D.C.  20549 and at certain of the
Commission's regional offices at the following addresses:  7 World Trade Center,
Suite 1300, New York, New York 10048;  Northwest Atrium Center, 500 West Madison
Street,  Suite 1400,  Chicago,  IL 60661.  Copies of this  material  also may be
obtained  from the Public  Reference  Section of the SEC,  at 450 Fifth  Street,
N.W., Room 1024, Washington,  D.C. at prescribed rates.  Electronic registration
statements made through the Electronic  Data  Gathering,  Analysis and Retrieval
System are publicly  available  through the Commission's  World Wide Web site at
http:\www.sec.gov.  The statements  contained in this Prospectus  concerning the
contents of any contract or document  referred to are not necessarily  complete,
and in each instance, reference is made to such contract or document filed as an
exhibit to the  Registration  Statement,  each statement  being qualified in all
respects by provisions  of such exhibit to which  reference is hereby made for a
full statement of the provisions thereof.




<PAGE>



                                   THE COMPANY

     The Company is engaged in the development of novel pharmaceuticals based on
innovative drug design technologies  targeting diseases of the eye,  principally
ocular inflammation, and the brain, principally stroke and head trauma.

     Its  leading  products  are  (i)  Lotemax(TM),   a  proprietary  ophthalmic
anti-inflammatory drug that has demonstrated significant efficacy in a series of
completed  Phase III  clinical  trials and a uniquely  superior  safety  profile
compared to currently  available  ophthalmic  steroids;  and (ii)  Alrex(TM),  a
product  with the same  active  ingredient  as  Lotemax , for the  treatment  of
seasonal allergic conjunctivitis.  On March 10, 1998, the Company, together with
Bausch & Lomb  Pharmaceuticals,  Inc.,  announced the approval from the Food and
Drug Administration ("FDA") to manufacture and market Lotemax and Alrex.

     The  Company's  principal  executive  offices are located at 33 Wood Avenue
South, Suite 466, Iselin, New Jersey 08830.


                                  RISK FACTORS

     The Common  Stock  being  offered  hereby  involves a high  degree of risk.
Prospective  investors should  carefully  consider the following risk factors in
addition to other  information  contained in this  Prospectus,  in evaluating an
investment in the shares of Common Stock offered hereby.

Early Stage of Development; Technological Uncertainty

     The Company is at an early  stage of  development.  Apart from  Lotemax and
Alrex, most of the Company's other potential  products are early in the research
and development phase, and product revenues may not be realized from the sale of
any such  products for at least the next several  years,  if at all. Many of the
Company's  proposed products will require  significant  additional  research and
development efforts prior to any commercial use, including extensive preclinical
and clinical  testing as well as lengthy  regulatory  approval.  There can be no
assurance  that  the  Company's   research  and  development   efforts  will  be
successful,  that the  Company's  potential  products  will prove to be safe and
effective in clinical trials or that any commercially  successful  products will
ultimately be developed by the Company.

History of Operating Losses; Accumulated Deficit

     The  Company  has  experienced   significant  operating  losses  since  its
inception.  As of March 31,  1998,  the  Company had an  accumulated  deficit of
approximately $73,702,422. The Company expects to incur operating losses over at
least the next several years as the Company's  research and development  efforts
and preclinical and clinical testing activities continue.  The Company's ability
to achieve profitability depends in part upon its ability, alone or with others,
to  successfully  commercialize  and  receive  approval  on its  first  proposed
product, to complete development of its

                                        1

<PAGE>



other  proposed  products,  to  obtain  required  regulatory  approvals  and  to
manufacture and market such products.

Future Capital Needs; Uncertainty of Additional Financing

     The Company's operations to date have consumed substantial amounts of cash.
The development of the Company's  technology and potential products will require
a  commitment  of  substantial  funds to conduct  the costly and  time-consuming
research necessary to develop and optimize such technology,  and ultimately,  to
establish manufacturing and marketing capabilities. The Company's future capital
requirements  will  depend  on  many  factors,  including  continued  scientific
progress in the research and  development  of the Company's  technology and drug
programs,  the ability of the Company to establish  and  maintain  collaborative
arrangements  with others for drug  development,  progress with  preclinical and
clinical trials, the time and costs involved in obtaining regulatory  approvals,
the costs involved in preparing, filing, prosecuting,  maintaining and enforcing
patent claims,  competing technological and market developments,  changes in its
existing  research   relationships   and  effective  product   commercialization
activities and arrangements.

     The Company  believes that its current cash  resources and interest  income
thereon,  including approximately $4.75 million in net cash and cash equivalents
received by the Company from the Private  Placement  Transaction,  combined with
anticipated cash inflows,  including  revenues expected to be derived from sales
of Lotemax and Alrex,  should be sufficient  to fund its operating  expenses and
capital requirements as currently planned through the first quarter of 1999. The
Company will seek  additional  funding  through  collaborative  arrangements  or
through  future  public or  private  equity or debt  financing.  There can be no
assurance that additional financing will be available on acceptable terms, or at
all. In addition,  pursuant to the Private  Placement  Transaction,  the Company
will not, except under certain limited  exceptions,  issue or agree to issue any
equity  securities at a price less than fair market value or any variably priced
securities  convertible into or exercisable or exchangeable for equity or equity
like  securities  of the Company for a period of one hundred  eighty  (180) days
following the Closing Date.  If  additional  funds are raised by issuing  equity
securities,  further dilution to stockholders may result.  If adequate funds are
not  available,  the Company  may be  required to delay,  reduce the scope of or
eliminate one or more of its research or development programs or to obtain funds
through arrangements with collaborative  partners or others that may require the
Company to relinquish rights to certain of its technologies,  product candidates
or products that the Company would  otherwise  seek to develop or  commercialize
itself.

Dependence on Potential Collaborative Partners

     The   Company's   strategy   for   the   development,   clinical   testing,
manufacturing,  marketing  and  commercialization  of  certain  of its  products
includes  entering  into  various   collaborations   with  corporate   partners,
licensors,  licensees  and  others.  To  date,  the  Company  has  entered  into
agreements  with  Bausch & Lomb to  manufacture  and market the  Company's  lead
products,  Lotemax and Alrex, in the United States and throughout Europe, Canada
and selected other

                                        2

<PAGE>



countries.  The agreements also cover the  co-development of LE-T, a combination
of loteprednol  etabonate and the anti-infective  tobramycin,  that is currently
being developed by the Company.  There can be no assurance that the Company will
be able to negotiate any future  collaborative  agreement  with Bausch & Lomb or
other companies on acceptable terms, or that any present or future collaborative
agreements will be successful.  To the extent that the Company chooses not to or
is not  able to  establish  such  arrangements,  the  Company  would  experience
increased capital  requirements to undertake such activities at its own expense.
In addition,  the Company may encounter  significant  delays in introducing  its
proposed products  currently under development into certain markets or find that
the development,  manufacture,  or sale of its proposed products in such markets
is adversely affected by the absence of such collaborative agreements.

Technological Change and Competition

     The  pharmaceutical  industry  is  subject  to  rapid,   unpredictable  and
significant  technological  change.  Competition  from  universities,   research
institutions and other pharmaceutical,  chemical and biotechnology  companies is
intense.  Many  competitors  or potential  competitors  have  greater  financial
resources,   research  and  development  capabilities,   and  manufacturing  and
marketing experience than the Company. To this end, the Company has entered into
agreements  with Bausch & Lomb for the  manufacture and marketing of Lotemax and
Alrex. There can be no assurance that developments by the Company's  competitors
or potential  competitors  will not render the Company's  technology or proposed
applications of its technology obsolete.

Technologies Subject to Licenses

     As a licensee  of certain  research  technologies,  the Company has various
license  agreements with certain U.S.  federal agencies and the State of Israel,
certain  universities  and Dr.  Nicholas  Bodor,  a former  vice  president  and
director  of the  Company,  wherein  the  Company  has  acquired  exclusive  and
coexclusive rights to develop and commercialize  certain research  technologies.
The  agreements  generally  require  the  Company  to pay  royalties  on sale of
products  developed  from the licensed  technologies  and fees on revenues  from
sublicensees,  where applicable, and the Company is responsible for the costs of
filing and prosecuting patent applications.  In addition,  some of the Company's
license  agreements  require that the Company  commit  certain sums annually for
research and development of the licensed products. Should the Company default on
its  obligations  under any of the  license  agreements,  such  agreement  would
terminate,  and the Company  would suffer  materially  adverse  effects from its
inability to use the licensed technology for research and product development.

     The exclusivity of license agreements generally expires fifteen years after
the  later  of  commercialization  or the  effectiveness  of the  patents.  Each
agreement  is  terminable  by either  party,  upon  notice,  if the other  party
defaults in its obligations.


                                        3

<PAGE>



Uncertainty of Protection of Patents and Proprietary Rights

     The  Company's  success  will depend in large part on its ability to obtain
patents,   maintain  trade  secrets  and  operate  without   infringing  on  the
proprietary  rights of  others,  both in the U.S.  and in other  countries.  The
patent positions of pharmaceutical companies can be highly uncertain and involve
complex   legal  and  factual   questions,   and   therefore   the  breadth  and
enforceability of claims allowed in pharmaceutical  patents cannot be predicted.
There  can be no  assurance  that any  issued  or  pending  patents  will not be
challenged,  invalidated or circumvented,  or that the rights granted thereunder
will provide proprietary protection or competitive advantages to the Company.

     The commercial success of the Company also will depend, in part, on Pharmos
not  infringing  patents  issued  to others  and not  breaching  the  technology
licenses upon which any Company products are based. It is uncertain  whether any
third-party patents will require the Company to alter its products or processes,
obtain licenses or cease certain activities.  In addition, if patents are issued
to others which contain  competitive or conflicting  claims, and such claims are
ultimately  determined  to be  valid,  the  Company  may be  required  to obtain
licenses to these patents or to develop or obtain alternative technology. If any
licenses are required,  there can be no assurance  that the Company will be able
to obtain any such  licenses on  commercially  favorable  terms,  if at all. The
Company's  breach of an  existing  license or failure to obtain a license to any
technology that it may require to commercialize its products may have a material
adverse  impact on the Company.  Litigation,  which could result in  substantial
costs to the Company,  may also be necessary to enforce any patents  licensed or
issued to the Company or to  determine  the scope and  validity  of  third-party
proprietary  rights.  If  competitors  of the  Company  prepare  and file patent
applications in the U.S. that claim technology also claimed by the Company,  the
Company may have to participate in interference proceedings declared by the U.S.
Patent and  Trademark  Office to determine  priority of  invention,  which could
result in  substantial  costs to the Company,  even if the  eventual  outcome is
favorable  to the  Company.  An adverse  outcome  could  subject  the Company to
significant liabilities to third parties, require disputed rights to be licensed
from third parties or require the Company to cease using such technology.

     The Company  also relies on secrecy to protect its  technology,  especially
where patent  protection is not believed to be appropriate or obtainable.  Thus,
Pharmos  protects  its  proprietary  technology  and  processes,   in  part,  by
confidentiality   agreements   with  its  employees,   consultants  and  certain
contractors.  There  can be no  assurance  that  these  agreements  will  not be
breached,  that the Company would have adequate remedies for any breach, or that
the Company's trade secrets will not otherwise  become known or be independently
discovered by competitors.


Extensive Government Regulation

     The Company's  products  require the approval of the FDA before they can be
marketed  in the U.S.  In  addition,  approvals  are also  required  from health
authorities  in most  foreign  countries  before the  Company's  products can be
marketed in such  countries.  Before an NDA, a type of submission used to obtain
FDA approval to market a new drug, can be filed with the FDA, a

                                        4

<PAGE>



product must undergo,  among other things,  extensive  animal  testing and human
clinical  trials,  which  can take up to seven  years to  complete.  Except  for
Lotemax and Alrex, the Company has not yet filed NDAs on its products.  The time
required for regulatory  approval of the Company's products after acceptance for
filing an NDA can vary and is usually  one to three  years or more,  and the FDA
may require  additional  animal studies and/or  clinical  trials before granting
approval. There can be no assurance that the FDA and foreign regulatory agencies
will be satisfied with the  information,  including that emanating from clinical
trials,  submitted to them in applications (like NDAs) seeking approval and will
approve  the  marketing  of any of the  Company's  potential  products,  or that
problems will not arise that could delay or prevent the commercialization of the
Company's future products.

     There can be no  assurance  that any  potential  products  developed by the
Company  alone or in  conjunction  with  others  will be  proven  to be safe and
effective  in  clinical  trials and will meet all of the  applicable  regulatory
requirements   needed  to  receive  marketing   approval.   Data  obtained  from
preclinical   testing  and  clinical   trials  can  be  susceptible  to  varying
interpretations  which could delay,  limit or prevent regulatory  approvals.  In
addition,  delays or  disapprovals  may be  encountered  based  upon  additional
government regulation resulting from future legislation or administrative action
or changes in FDA policy made during the period of product  development  and FDA
regulatory review.  Similar delays may also be encountered in foreign countries.
There can be no assurance that even after such time and expenditures, regulatory
approval will be obtained for any potential  products  developed by the Company.
If regulatory approval of a product is granted, such approval will be limited to
those  therapeutic  uses for which the  product  has been  demonstrated  through
clinical studies and other means to be safe and effective. Furthermore, approval
may entail ongoing requirements for post-marketing  studies.  Even if regulatory
approval is obtained, a marketed product, its manufacturer and its manufacturing
facilities  are  subject to  continual  review  and  periodic  inspections.  The
regulatory  standards for manufacturing are currently being applied  stringently
by  the  FDA.   Discovery  of  previously   unknown  problems  with  a  product,
manufacturer  or facility  may result in FDA  restrictions  being placed on such
product or manufacturer  or facility,  including an order to withdraw a specific
product from the market, and may also result in court enforced sanctions against
the product, manufacturer or facility.

     The Company may establish  collaborative  relationships to conduct clinical
testing and seek  regulatory  approvals to market its products in major  markets
outside the U.S.  There can be no assurance  that the Company will be successful
in establishing such  relationships or that such approvals will be received in a
timely  manner,  if at all. To market its products  abroad,  the Company is also
subject to numerous and varying foreign regulatory requirements,  implemented by
foreign health  authorities,  governing the design and conduct of human clinical
trials, pricing and marketing. The approval procedure varies among countries and
can involve  additional  testing,  and the time required to obtain  approval may
differ from that required to obtain FDA approval. At present,  foreign marketing
authorizations are applied for at a national level, although within the European
Union ("EU") certain registration  procedures are available to companies wishing
to  market  a  product  in more  than one EU  member  country.  If a  regulatory
authority is satisfied  that adequate  evidence of safety,  quality and efficacy
has been presented, marketing authorization is

                                        5

<PAGE>



almost always granted.  The foreign regulatory  approval process includes all of
the risks  associated  with obtaining FDA approval set forth above.  Approval by
the FDA does not ensure approval by other countries.

Lack of Sales and Marketing Capability

     The Company has no  experience  in sales,  marketing  or  distribution.  To
market any of its products directly,  the Company must develop a marketing force
and sales  force  with  technical  expertise  and with  supporting  distribution
capability.   Alternatively,   the  Company  may  obtain  the  assistance  of  a
pharmaceutical company with an established  distribution system and sales force.
The Company has entered into agreements with Bausch & Lomb to market Lotemax and
Alrex.  There can be no  assurance,  however,  that the Company  will be able to
establish sales and distribution capabilities or be successful in gaining market
acceptance for its products.

Lack of Manufacturing Capability

     The Company currently does not have manufacturing facilities to produce its
products  for  clinical  trials.  The  Company's  agreements  with Bausch & Lomb
provide for the  manufacturing of Lotemax and Alrex. The proposed products under
development by the Company have never been  manufactured  on a commercial  scale
and there can be no assurances  that such products can be manufactured at a cost
or in  quantities  necessary  to make  them  commercially  viable.  Any delay in
availability  of products may result in delay in the  submission of products for
regulatory  approval or the market  introduction  and  subsequent  sales of such
products, which would have a material adverse effect on the Company.

Need to Attract and Retain Key Employees and Consultants

     The Company is highly dependent on the principal  members of its scientific
and  management  staff.  In  addition,  the Company  relies on  consultants  and
advisors to assist the  Company in  formulating  its  research  and  development
strategy. Retaining and attracting qualified personnel, consultants and advisors
will be  critical  to the  Company's  success.  In order to pursue  its  product
development and marketing plans, the Company will be required to hire additional
qualified scientific  personnel to perform research and development,  as well as
personnel   with   expertise  in  clinical   testing,   government   regulation,
manufacturing  and  marketing.  The  Company  faces  competition  for  qualified
individuals   from  numerous   pharmaceutical   and   biotechnology   companies,
universities and other research institutions. There can be no assurance that the
Company will be able to attract and retain such  individuals on acceptable terms
or at all.

     The Company's  clinical  development  is conducted  under  agreements  with
universities and medical  institutions.  The Company depends on the availability
of a principal investigator for each such program, and the Company cannot assure
that these  individuals  or their  research  staffs will be available to conduct
clinical development.  The Company's academic collaborators are not employees of
the Company.  As a result, the Company has limited control over their activities
and can expect  that only  limited  amounts of their time will be  dedicated  to
Company activities. The

                                        6

<PAGE>



Company's  academic  collaborators may have  relationships with other commercial
entities, some of which compete with the Company.

Uncertainty of Health Care Reform Measures and Third-Party Reimbursement

     The  levels  of   revenues   and   profitability   of   biotechnology   and
pharmaceutical   companies  may  be  affected  by  the  continuing   efforts  of
governmental  and  third-party  payors to  contain or reduce the costs of health
care through various means. For example, in certain foreign markets,  pricing or
profitability of prescription  pharmaceuticals is subject to government control.
In the U.S.,  there have been, and the Company  expects that there will continue
to be, a number of federal  and state  proposals  to control  health care costs.
While the Company  cannot  predict  whether any such  legislative  or regulatory
proposals will be adopted or the effect such proposals may have on its business,
the uncertainty  surrounding such proposals could have a material adverse effect
on  the  Company.  Furthermore,  the  Company's  ability  to  commercialize  its
potential  product  portfolio may be adversely  affected to the extent that such
proposals have a material  adverse effect on the business,  financial  condition
and  profitability  of other  companies that are prospective  collaborators  for
certain of the Company's proposed products.

Dependence on Reimbursement

     Pharmos' ability to commercialize  its products  successfully may depend in
part on the  extent to which  reimbursement  for the cost of such  products  and
related  treatments  will be available  from  government  health  administration
authorities, private health insurers and other organizations. Third-party payors
are  increasingly  challenging  the  price of  medical  products  and  services.
Significant  uncertainty exists as to the reimbursement status of newly approved
health care products,  and there can be no assurance  that adequate  third-party
coverage will be available to enable Pharmos to maintain price levels sufficient
to realize an appropriate return on its investment in product development.

Risk of Product Liability; Availability of Insurance

     The design,  development and manufacture of the Company's  products involve
an inherent risk of product liability claims and associated  adverse  publicity.
Although the Company currently maintains general liability insurance,  there can
be no assurance  that the coverage  limits of the Company's  insurance  policies
will be adequate.  Similarly,  the Company  currently  maintains  clinical trial
liability  insurance,  but there can be no assurance  that the coverage limit of
the Company's insurance policies will be adequate.  The Company currently has no
product liability insurance, and there can be no assurance that the Company will
be able to obtain or maintain product liability insurance on acceptable terms or
with  adequate  coverage  against  potential  liabilities.   Such  insurance  is
expensive,  difficult  to  obtain  and may not be  available  in the  future  on
acceptable  terms or at all. A successful  claim brought  against the Company in
excess of the Company's  insurance coverage could have a material adverse effect
upon the Company and its financial condition.


                                        7

<PAGE>



Use of Hazardous  Materials;  Potential  Liability to Comply with  Environmental
Laws

     The  Company's  research and  development  involves the  controlled  use of
hazardous  materials.  Although the Company believes that its safety  procedures
for handling and  disposing of such  materials  comply in all material  respects
with the  standard  prescribed  by state and  federal  regulations,  the risk of
accidental  contamination  or injury from these  materials  cannot be completely
eliminated.  In the event of such an accident,  the Company could be held liable
for any damages that result,  and any such liability  could exceed the resources
of the  Company.  The  Company  may  incur  substantial  costs  to  comply  with
environmental regulations if the Company develops manufacturing capacity.

Market for the Company's  Securities;  Shares Eligible for Future Sale; Possible
Volatility of Share Prices

     The market price of the Company's Common Stock, like that of other emerging
pharmaceutical  companies,  has fluctuated  significantly in recent years and is
likely to  fluctuate  in the  future.  Announcements  by the  Company  or others
regarding  scientific  discoveries,   technological   innovations,   litigation,
products,  patents or  proprietary  rights,  the  progress of  clinical  trials,
government  regulation,  public  concern  as to the  safety  of  drugs  and  the
reliability of the Company's testing processes and general market conditions may
have a significant  impact on the market price of the Common Stock. The addition
of the shares being offered hereby and the shares  issuable upon exercise of the
Company's  currently   outstanding   warrants  and  options  to  the  number  of
publicly-traded  shares of the Company's  Common Stock may affect the volatility
of share prices of the Company's Common Stock.

Dilution as a result of Conversion of Preferred Stock and exercise of Warrants

   
     The Selling  Stockholders  hold 5,000 shares of Series C Preferred Stock of
the  Company,   which  are   convertible   into  Common  Shares.   See  "Selling
Stockholders."  Each share of Series C  Preferred  Stock is  convertible  into a
number  of  shares  of  Common  Stock  equal to (i)  $1,000  (ii)  divided  by a
conversion  price which is currently  90% of the average of the low trade prices
of the Common  Stock for the five (5)  consecutive  trading  days  ending on the
trading day immediately  preceding the conversion date (the "Variable Conversion
Price") and on and after  August 2, 1998 the lesser of the  Variable  Conversion
Price and a number of shares of Common Stock equal to (i) $1,000 (ii) divided by
a conversion  price which is one hundred twenty percent (120%) of the average of
the closing bid prices of the Common  Stock for the trading  days  beginning  on
July 4, 1998 and  ending on August 2, 1998 (in each case  subject  to  equitable
adjustment  for any stock  splits,  stock  dividends  and  reclassifications  or
similar events during the period.  Under the applicable  conversion  formulas of
the  Series C  Preferred  Stock,  the  number of  Common  Shares  issuable  upon
conversion is inversely proportional to the market price of the Common Shares at
the time of conversion (i.e., the number of shares increases as the market price
of the Common Shares  decreases);  and except with respect to certain redemption
rights of the Company for the Series C Preferred Stock and the limitation  under
Nasdaq SmallCap  regulations  which limit the aggregate  amount of Common Shares
which the Company may issue at a discount  from market price upon  conversion of
the Series C Preferred Stock and Warrants without  stockholder  approval,  (such
stockholder approval is being requested by the
    

                                        8

<PAGE>



Company),  there is no cap on the number of shares of Common  Stock which may be
issued. In addition, the number of Common Shares issuable upon the conversion of
the  Series C  Preferred  Stock and the  exercise  of  Warrants  is  subject  to
adjustment  upon the  occurrence  of  certain  dilutive  events.  For a  further
description  of the  rights of  holders  of Series C  Preferred  Stock,  see the
Designations,  Preferences  and  Rights  of Series C  Convertible  Participating
Preferred  Stock of Pharmos  Corporation  filed as an  exhibit to the  Company's
Current Report on Form 8-K,  dated  February 4, 1998.  The Selling  Stockholders
also hold  outstanding  Warrants to acquire  821,052 Common Shares.  All of such
Common  Shares  are  covered  by  the  registration  statement  containing  this
Prospectus or will be covered by subsequent registration statements filed by the
Company,  if  necessary.  The exercise of such  Warrants and  conversion of such
Series  C  Preferred  Stock  and the sale of such  Common  Shares  could  have a
significant  negative  effect on the market  price of the Common Stock and could
materially impair the Company's ability to raise capital through the future sale
of equity securities.

Outstanding Stock Options and Warrants

   
     As of June 30, 1998, the Company had outstanding incentive stock options to
purchase an aggregate of 484,669  shares of Common Stock at an average  exercise
price of $2.17  per  share  and  non-qualified  stock  options  to  purchase  an
aggregate of 439,265 at an average  exercise  price of $2.63 per share issued to
employees,  directors  and  consultants  pursuant  to  stock  option  plans  and
individual  agreements with management and directors of the Company and warrants
(excluding the Warrants) to purchase  3,709,713  shares of the Company's  Common
Stock at an average price of $1.91 per share.
    

     The Company may issue additional capital stock,  warrants and/or options to
raise capital in the future.  The Company  regularly  examines  opportunities to
expand its  technology  base and product  line  through  means such as licenses,
joint  ventures and  acquisition  of assets or ongoing  businesses and may issue
securities in connection  with such  transactions.  However,  no  commitments to
enter  into or pursue  any such  transaction  have been made and there can be no
assurance that any such discussions  will result in any such  transaction  being
concluded.  In order to attract and retain key  personnel,  the Company may also
issue  additional  securities,  including stock options,  in connection with its
employee  benefit  plans.  During the terms of such  options and  warrants,  the
holders  thereof are given the  opportunity  to profit from a rise in the market
price of the Company's  Common Stock.  The exercise of such options and warrants
may have an adverse  effect on the market value of the  Company's  Common Stock.
Also, the existence of such options and warrants may adversely  affect the terms
on which the Company can obtain additional equity financing.


Anti-Takeover Provisions

     The  Company is  subject  to  Sections  78.411-.444  of the Nevada  General
Corporation  Law ("Nevada  Law"),  an  anti-takeover  law,  which may discourage
certain types of transactions involving an actual or potential change in control
of the Company, including transactions in which the stockholders might otherwise
receive a premium for their  shares over the current  prices,  and may limit the
ability of the stockholders to approve a transaction that they may deem to be in
their

                                        9

<PAGE>



best interests.  In addition,  the Board of Directors has the authority  without
action by the stockholders to fix the rights and preferences of and issue shares
of Preferred Stock, which may have the effect of delaying or preventing a change
in control of the Company.

Potential Future Acquisitions

     Due to the  current  uncertainties  of the  capital  markets  for  emerging
pharmaceutical  companies,  the Company  has had  preliminary  discussions  with
several  emerging  pharmaceutical  and  biotechnology  companies about potential
business and/or product consolidations, joint ventures, acquisitions, mergers or
other  business  combinations  (collectively  "acquisitions").  In the event the
Company undertakes any such acquisitions it may use some of its cash,  including
part of the cash received in connection with the Private Placement  Transaction,
or may  issue its  stock in  connection  therewith.  Although  management  would
attempt to structure such  acquisitions in a manner that will minimize  dilution
of the equity  owned by current  stockholders,  no  assurance  can be given that
acquisitions  will not result in such  dilution  or that  control of the Company
will not be changed as a result of such  acquisitions.  Such acquisitions may be
negotiated or may be sought on an unsolicited basis and may involve  speculative
and risky  undertakings by the Company with increased risks to its stockholders.
Under Nevada law, acquisitions do not require shareholders' approval except when
accomplished  by merger or  consolidation.  The  Company  does not,  in general,
intend to submit  acquisitions  to  shareholder  vote except  where  required by
Nevada law. The Company has not entered into any  preliminary  undertaking  with
any third  parties  involving any  acquisitions  or other  business  combination
transactions.

Special Considerations of Doing Business in Israel

     A significant  part of the operations of the Company is conducted in Israel
through its wholly-owned  subsidiary,  Pharmos Limited ("Pharmos Ltd."),  and is
directly  affected by economic,  political  and military  conditions  there.  In
addition, Pharmos Ltd. has received certain funding from the Office of the Chief
Scientist of the Israel  Ministry of Industry and Trade (the "Chief  Scientist")
relating to its proprietary SubMicron Emulsion Technology and to Dexanabinol,  a
new chemical entity.  Such funding prohibits the transfer or license of know-how
and the  manufacture  of  resulting  products  outside  of  Israel  without  the
permission of the Chief Scientist.  Although it is the Company's belief that the
Chief Scientist does not unreasonably withhold this permission if the request is
based upon commercially  justified  circumstances and any royalty obligations to
the Chief  Scientist are  sufficiently  assured,  there can be no assurance that
such consent,  if  requested,  would be granted upon terms  satisfactory  to the
Company or granted at all.

Absence of Dividends

     No dividends  have been paid on the Common  Stock to date,  and the Company
does not expect to pay cash dividends in the foreseeable future.


                                       10

<PAGE>


                                    DILUTION

     As of March 31,  1998,  the net  tangible  book  value of the  Company  was
$2,508,738  or $0.07 per share.  Net tangible book value per share is determined
by dividing the net tangible book value  (tangible  assets less  liabilities) of
the Company by the number of shares of Common Stock outstanding at that date.

   
     If all of the 500,000  Warrants  exercisable  at an exercise price of $2.67
per share are  exercised,  (each of the Warrants  purchasing one share of Common
Stock),  there would be 36,765,119 shares of Common Stock outstanding with a net
tangible book value of $0.11 and the  purchasers of shares  through the exercise
of such  Warrants at such prices  would suffer  immediate  dilution of $2.56 per
share.
    

     If all of the 150,000  Warrants  exercisable  at an exercise price of $2.28
per share are  exercised,  (each of the Warrants  purchasing one share of Common
Stock),  there would be 36,415,119 shares of Common Stock outstanding with a net
tangible book value of $0.08 and the  purchasers of shares  through the exercise
of such  Warrants at such prices  would suffer  immediate  dilution of $2.20 per
share.

     If all of the 171,052  Warrants  exercisable  at an exercise price of $1.38
per share are  exercised,  (each of the Warrants  purchasing one share of Common
Stock),  there would be 36,436,171 shares of Common Stock outstanding with a net
tangible book value of $0.08 and the  purchasers of shares  through the exercise
of such  Warrants at such prices  would suffer  immediate  dilution of $1.30 per
share.

   
     If all of the Warrants are exercised,  (each of the Warrants purchasing one
share of Common  Stock),  there  would be  37,086,171  shares  of  Common  Stock
outstanding  with a net tangible book value of $0.12.  The  purchasers of shares
through the exercise of such Warrants at a price of $2.67 per share would suffer
immediate  dilution of $2.55 per share;  the  purchasers  of shares  through the
exercise of such  Warrants at a price of $2.28 per share would suffer  immediate
dilution of $2.16 per share;  and the  purchasers of shares through the exercise
of such Warrants at a price of $1.38 per share would suffer  immediate  dilution
of $1.26 per share.
    

                                 USE OF PROCEEDS

     The Company will receive no proceeds  from the  6,000,000  shares of Common
Stock to be offered and resold by the Selling Stockholder.

   
     If all 821,052  Warrants  whose  underlying  Common Stock is being  offered
hereby are  exercised,  the gross proceeds to be received by the Company will be
$1,913,052  (assuming  that the  cashless  exercise  option  is not used for the
500,000  Warrants  exercisable  at an  exercise  price of $2.67 and the  150,000
Warrants  exercisable at an exercise price of $2.28).  Any proceeds  received by
the Company from the exercise of the Warrants will be used for working capital.
    


                                       11

<PAGE>


     The Company  believes that its current cash  resources and interest  income
thereon,  including the funds obtained from the Private  Placement  Transaction,
should be sufficient to fund its operating expenses and capital  requirements as
currently  planned  through the first quarter of 1999. The amounts and timing of
expenditures  for each  purpose  will depend on the  progress  of the  Company's
research and development programs, technological advances,  determinations as to
commercial potential,  the terms of any collaborative  arrangements entered into
by the Company for development and licensing,  regulatory  approvals,  and other
factors, many of which are beyond the Company's control.  Pending such uses, the
cash  received in  connection  with the Private  Placement  Transaction  will be
invested  in  short-term,   interest-bearing  investment  grade  securities  and
commercial paper.


                            DESCRIPTION OF SECURITIES

Common Stock

     The Common Stock being offered hereby (i) by the Selling Stockholder,  (ii)
by the Company upon the exercise of the Warrants,  and (iii) by any  "affiliate"
of the Company upon the resale of such Common Stock obtained from exercising the
Warrants is fully described in the Company's  Registration Statement on Form 8-A
dated January 30, 1984, filed pursuant to Section 12 of the Securities  Exchange
Act of 1934, as amended (the  "Exchange  Act").  See  "Incorporation  of Certain
Documents by Reference".

   
     The Company's  Restated Articles of Incorporation  currently  authorize the
issuance of up to 60,000,000  shares of Common Stock. As of June 30, 1998, there
were 37,055,886 shares outstanding.
    

Preferred Stock

   
     The Company's  Restated Articles of Incorporation  currently  authorize the
issuance  of up to  1,250,000  shares  of  Preferred  Stock.  Of the  authorized
Preferred Stock, no shares,  designated as Series A or Series B Preferred Stock,
are currently  outstanding.  In addition,  5,000 shares,  designated as Series C
Preferred  Stock,  are currently  issued and outstanding and held by the Selling
Stockholder.  There  are an  additional  3,000  shares,  designated  as Series C
Preferred  Stock  which may be issued at the  discretion  of the  Company to the
current Selling Stockholder. The Company, however, does not intend to issue such
shares.  The Series C Preferred Stock was issued in connection with the February
1998  Private  Placement  Transaction  (the  "Private  Placement  Transaction").
Holders of Series C Preferred  Stock have the right to convert  their  shares as
follows:  at 90% of the average of the lowest sale price of the Common Stock for
the  five  consecutive  trading  days  ending  on the  trading  day  immediately
preceding the Conversion for the first 6 months after closing;  thereafter,  the
conversion  price will equal the lower of (i) 90% of the then prevailing  market
prices,  as determined above, or (ii) 120% of the average closing bid prices for
days 151-180 following the closing.  For a complete description of the rights of
holders of
    

                                       12

<PAGE>



Series  C  Preferred  Stock,  see the  Company's  Current  Report  on Form  8-K,
including the exhibits thereto, dated February 4, 1998.

Warrants

   
     The  500,000  Warrants  exercisable  at an  exercise  price  of  $2.67  are
exercisable  commencing  February 4, 1999 and expire on  February  4, 2003;  the
150,000  Warrants  exercisable  at an  exercise  price of $2.28 are  exercisable
commencing  February  4, 1999 and expire on  February  4, 2003;  and the 171,052
Warrants exercisable at an exercise price of $1.38 are exercisable commencing on
March 31,  1998 and  expire  on March  31,  2008.  All of the  Warrants  contain
anti-dilution  provisions  providing  for  an  adjustment  to  their  respective
exercise  prices in the event that the  Company  effects a stock  split or stock
dividend. In addition,  the number and kind of shares of Common Stock underlying
the  Warrants  are  subject  to   adjustments   in  the  event  of  any  capital
reorganization,  or  reclassification  of the capital  stock of the Company,  or
consolidation or merger of the Company with another corporation or entity (other
than a  subsidiary  of the  Company  in which the  Company is the  surviving  or
continuing corporation and no change occurs in the Company's Common Stock).
    

Other Securities--Preferred Stock

     The Company's  Restated Articles of Incorporation  currently  authorize the
issuance of up to  1,250,000  shares of Preferred  Stock,  of which no shares of
Series A or Series B Preferred Stock are currently outstanding, and 5,000 shares
of Series C Preferred  Stock  issued in  connection  with the Private  Placement
Transaction  are  currently  issued and  outstanding  as of March 2,  1998,  and
empower the Board of  Directors,  without  the  necessity  of further  action or
authorization by the stockholders,  to authorize the issuance of Preferred Stock
from  time  to  time  in one or more  series  and to fix  the  relative  rights,
preferences and limitations of each such series. The issuance of Preferred Stock
could  adversely  affect  the voting  power of  holders of Common  Stock and the
likelihood  that such holders will receive  dividend  payments and payments upon
liquidation  and could have the effect of delaying,  deferring  or  preventing a
change in control of the  Company.  The Company has no present plan to issue any
additional shares of Preferred Stock.

Other Securities--Options and Warrants

   
     As of June 30, 1998, the Company had outstanding incentive stock options to
purchase an aggregate of 484,669  shares of Common Stock at an average  exercise
price of $2.17  per  share  and  non-qualified  stock  options  to  purchase  an
aggregate of 439,265 at an average  exercise  price of $2.63 per share issued to
employees,  directors  and  consultants  pursuant  to  stock  option  plans  and
individual  agreements with management and directors of the Company and warrants
(excluding the Warrants) to purchase  3,709,713  shares of the Company's  Common
Stock at an average price of $1.91 per share,  consisting of:  112,979  warrants
which can be exercised  until  February  1999 each to purchase a single share of
Common Stock for $2.44;  454,121  warrants  which can be exercised  until August
1999 each to purchase a single share of Common Stock for $2.67; 65,044
    

                                       13

<PAGE>



   
warrants which can be exercised  until  September 1999 each to purchase a single
share of Common Stock for $2.26;  150,000  warrants which can be exercised until
October 1999 each to purchase a single share of Common Stock for $0.84;  500,000
warrants which can be exercised until April 2005 each to purchase a single share
of Common Stock for $2.75;  10,000  Warrants which can be exercised  until April
2005 each to purchase a single share of Common Stock for $0.78;  7,119  warrants
which can be  exercised  until  April 2000 each to  purchase  a single  share of
Common Stock for $.75;  17,119  Warrants which can be exercised until April 2000
each to purchase a single share of Common Stock for $1.00; 17,119 warrants which
can be  exercised  until  April 2000 each to  purchase a single  share of Common
Stock for $1.50;  821,489  warrants which can be exercised  until September 2000
each to purchase a single share of Common Stock for $1.80; 10,000 warrants which
can be  exercised  until  October 2001 each to purchase a single share of Common
Stock for $1.88; 15,000 warrants which can be exercised until March 2002 each to
purchase a single share of Common Stock for $2.31;  65,000 warrants which can be
exercised  until  September 2007 each to purchase a single share of Common Stock
for $1.34;  50,000  warrants which can be exercised until September 2007 each to
purchase a single share of Common Stock for $1.75;  10,000 warrants which can be
exercised  until  November  2002 each to purchase a single share of Common Stock
for $1.39;  110,000  warrants which can be exercised until February 2003 each to
purchase a single share of Common Stock for $1.59; 849,250 warrants which can be
exercised  until  February  2007 each to purchase a single share of Common Stock
for $1.59;  159,000  warrants  which can be  exercised  until March 2001 each to
purchase a single share of Common Stock for $1.75;  10,000 warrants which can be
exercised  until March 2007 each to purchase a single  share of Common Stock for
$1.66; 239,473 warrants which can be exercised until March 2008 each to purchase
a single share of Common Stock for $1.38; 15,000 warrants which can be exercised
until April 2003 each to purchase a single share of Common Stock for $1.22.; and
22,000  warrants  which can be exercised  until  October 2005 each to purchase a
single share of Common Stock for $2.22.
    

Nevada Anti-Takeover Laws

     The Company is subject to the provisions of Sections  78.411 through 78.444
of  the  Nevada  Law,  an  anti-takeover   statute  (the  "Business  Combination
Statute").   In  general,   the  Business   Combination   Statute   prohibits  a
publicly-held  Nevada  corporation  from  engaging  in a  "combination"  with an
"interested  stockholder"  for a period  of three  years  after  the date of the
transaction  in which the person became an interested  stockholder,  unless such
combination is approved in a prescribed  manner or satisfies  certain fair value
requirements.   For  the   purposes  of  the   Business   Combination   Statute,
"combination"  includes a merger, an asset sale, the issuance or transfer by the
corporation of its shares in one transaction or a series of transactions, having
an aggregate  fair market  value equal to five percent or more of the  aggregate
market  value  of  the  corporation's  outstanding  shares,  to  the  interested
stockholder or to an associate of the interested stockholder,  and certain other
types  of  transactions   resulting  in  a  financial   benefit  the  interested
stockholder.  An  "interested  stockholder"  is a person  who is the  beneficial
owner,  directly  or  indirectly,  of ten  percent or more of the  corporation's
voting stock or an affiliate  or associate of the  corporation  that at any time
within the three years immediately preceding the date in question

                                       14

<PAGE>



was the beneficial owner, directly or indirectly,  of ten percent or more of the
corporation's voting stock.

     By an amendment to its  By-laws,  the Company has exempted  itself from the
provisions  of  Sections  78.378  through  78.3793 of the Nevada Law, a "control
share"  statute which  otherwise  prohibits an acquiring  person,  under certain
circumstances,  from voting certain shares of a target corporation's stock after
such  acquiring  person's  percentage of ownership of such  corporation's  stock
crosses  certain  thresholds,  unless  the  target  corporation's  disinterested
stockholders approve the granting of voting rights to such shares.

Transfer Agent and Registrar

     The transfer agent and registrar for the Company's Common Stock is American
Stock Transfer and Trust Company, New York, New York.


                              PLAN OF DISTRIBUTION

   
     The  shares  of  Common  Stock  will be  offered  and  sold by the  Selling
Stockholders  for their own accounts.  The Company will not receive any proceeds
from the sale of the Common Stock pursuant to this  Prospectus.  The Company has
agreed to pay the expenses of registration of the Common Shares, including legal
and accounting fees.

     The Company will receive no proceeds  from this  offering  (other than from
the  exercise of the  Warrants).  The Shares  offered  hereby may be sold by the
Selling Stockholders or by pledgees,  donees, transferees or other successors in
interest that receive such shares as a gift,  partnership  distribution or other
non-sale  related  transfer.  The  Shares  may be  sold  from  time  to  time in
transactions in the over-the-counter  market, in negotiated  transactions,  or a
combination  of such methods of sale,  at fixed prices which may be changed,  at
market prices  prevailing  at the time of sale, at prices  related to prevailing
market prices or at negotiated prices. The Selling  Stockholders may effect such
transactions by selling the Shares to or through broker-dealers, including block
trades in which  brokers or dealers will attempt to sell the Shares as agent but
may position and resell the block as principal to facilitate the transaction, or
in one or more underwritten offerings on a firm commitment or best effort basis.
Sales of  Selling  Stockholders'  Shares may also be made  pursuant  to Rule 144
under the Securities Act, where applicable.

     To the extent  required under the Securities  Act, the aggregate  amount of
Selling  Stockholders'  Shares being offered and the terms of the offering,  the
names of any such agents, brokers, dealers,  transferees or underwriters and any
applicable commission with respect to a particular offer will be set forth in an
accompanying Prospectus supplement. Any underwriters, dealers, brokers or agents
participating in the distribution of the Shares may receive  compensation in the
form of  underwriting  discounts,  concessions,  commissions  or fees  from  the
Selling Stockholders and/or purchasers of Selling Stockholders' Shares, for whom
they may act (which  compensation as to a particular  broker-dealer  might be in
excess of customary commissions).
    


                                       15

<PAGE>


   
     From time to time,  the Selling  Stockholders  may pledge,  hypothecate  or
grant  a  security  interest  in some or all of the  Shares,  and the  pledgees,
secured parties or persons to whom such securities have been hypothecated shall,
upon foreclosure in the event of default,  be deemed to be Selling  Stockholders
hereunder.  In addition,  the Selling  Stockholders may, from time to time, sell
short the Shares of the Company,  and in such instances,  this Prospectus may be
delivered in connection  with such short sales and the Shares offered hereby may
be used to cover such short sales.

     From time to time, the Selling Stockholders may transfer, pledge, donate or
assign Shares to lenders or others and each of such persons will be deemed to be
a  "Selling  Stockholder"  for  purposes  of the  Prospectus.  The number of the
Selling  Stockholders'  Shares  beneficially owned by a Selling  Stockholder who
transfers,  pledges,  donates or assigns  Shares will  decrease as and when they
take such actions,  The plan of distribution  for Selling  Stockholders'  Shares
sold hereunder will otherwise  remain  unchanged,  except that the  transferees,
pledgees, donees or other successors will be a Selling Stockholder hereunder.

     A  Selling   Stockholder   may  enter  into   hedging   transactions   with
broker-dealers,  and the  broker-dealers may engage in short sales of the Shares
in  the  course  of  hedging  the  positions   they  assume  with  such  Selling
Stockholder,  including, without limitation , in connection with distribution of
the Shares by such broker-dealers.  The Selling Stockholders may also enter into
option or other  transactions with  broker-dealers  that involve the delivery of
the Shares to the broker-dealers, who may then resell or otherwise transfer such
Shares.  The  Selling  Stockholders  may also  loan or  pledge  the  Shares to a
broker-dealer  and the  broker-dealer  may sell the  Shares  as loaned or upon a
default may sell or otherwise transfer the pledge Shares.

     In  order  to  comply  with  the  securities  laws of  certain  states,  if
applicable,  the  Shares  will  be  sold  in  such  jurisdictions  only  through
registered or licensed  brokers or dealers.  In addition,  in certain states the
Shares may not be sold unless they have been registered or qualified for sale in
the applicable  state or an exemption  from the  registration  or  qualification
requirement is available.

     The Selling  Stockholders and any  broker-dealer or agent that participates
with the Selling Stockholders in the distribution of the Shares may be deemed to
be  "underwriter"  within the meaning of the Securities Act, and any commissions
received  by them and any profit on the resale of the Shares  purchased  by them
may be deemed to be underwriting commissions under the Securities Act.

     The  Company  has agreed to pay  certain  costs and  expenses  incurred  in
connection  with the  registration of the shares of Common Stock offered hereby,
except  that the  Selling  Stockholders  shall be  responsible  for all  selling
commissions, transfer taxes and related charges in connection with the offer and
sale of such shares.

     The Company  has agreed to keep the  Registration  Statement  of which this
Prospectus  forms a part  continuously  effective  until the earlier of the date
that all of such  Shares  have  been sold or three  years  from the date of this
Prospectus.
    

                                       16

<PAGE>

   

                            SELLING SECURITY HOLDERS

     The table  below sets forth the name of each of the  Selling  Stockholders,
the total  amount  of (i)  shares of  Common  Stock  beneficially  owned by such
security  holders as of June 30, 1998,  (ii) Warrant  Shares  issuable  upon the
exercise of the Warrants beneficially owned by such security holders;  (iii) the
aggregate  amount of Common Stock and/or Warrant Shares which may be offered for
sale for the account of such security holders in his/her discretion from time to
time pursuant to this  Prospectus;  and (iv) the amount and percentage of Common
Stock which would be beneficially  owned by such security  holders after sale of
all securities offered by the Selling Stockholders  pursuant to this Prospectus,
if they are offered and sold,  and  assuming  that any other shares held by such
security  holders are not sold.  The  information  included  below is based upon
information  provided by the Selling  Stockholders.  The Selling Stockholders as
referred to herein have not held any  position  or office,  or had any  material
relationship,  with the Company or any of its predecessors or affiliates  within
the last three years,  except as noted below, and the Selling  Stockholders will
not own 1% or more of the outstanding  stock of the Company after  completion of
the offering, except as noted below.

<TABLE>
<CAPTION>
                                                                                       Shares and Percentage of Shares     
                                 Shares of          Shares of         Percentage       Owned After Completion of          
             Names               Common Stock       Common Stock      of Shares        Offering                            
(and position or office held in  Beneficially       and/or Warrant    Owned Prior      ----------------------------------- 
the Company)                     Owned(1)           Shares Offered    to Offering      Shares             Percentage       
===============================  =================  ================= ===============  ================  ================= 
<S>                                   <C>                <C>                     <C>                  <C>                <C>
Alan Mark(2)                            171,052(3)            171,052              **                 0                  0
- -------------------------------  -----------------  ----------------- ---------------  ----------------  -----------------
Gemini Capital                                0(4)            150,000              **                 0                  0
- -------------------------------  -----------------  ----------------- ---------------  ----------------  -----------------
CC Investments, LDC (5)               1,817,222(6)       6,500,000(7)            4.9%                 0                  0
- -------------------------------  -----------------  ----------------- ---------------  ----------------  -----------------
</TABLE>

- --------------------

**   Less than 1%.

(1)  Beneficial  ownership is  determined  in  accordance  with the rules of the
     Securities  and  Exchange  Commission  and  generally  includes  voting  or
     investment  power with respect to  securities  and includes any  securities
     which the person has the right to acquire  within 60 days of July 14,  1998
     through the conversion or exercise of any security or other right.

(2)  Alan Mark served as Acting Chief Financial Officer of the Company from July
     1, 1996 to July 31, 1997.

(3)  Consists of currently  exercisable  Warrants to purchase  171,052 shares of
     Common Stock at an exercise price of $1.38 per share.

(4)  Gemini Capital holds Warrants to purchase 150,000 shares of Common Stock at
     an exercise  price of $2.28 per share which are not  exercisable  within 60
     days of July 14, 1998.

(5)  Castle Creek Partners, LLC is the investment advisor to CC Investments, LDC
     and  consequently  may be  deemed to have  voting  control  and  investment
     discretion  over the securities  held by CC Investments  LDC.  Castle Creek
     Partners  disclaims  beneficial  ownership  of all  securities  owned by CC
     Investments LDC. David
    

                                       17

<PAGE>

   
     Asher and John Ziegelman may be deemed to be the  beneficial  owners of the
     securities held by CC Investments LDC. Mr. Asher and Mr. Ziegelman disclaim
     such beneficial  ownership.  The address CC Investments,  LDC, is c/o Citco
     Fund Services,  Ltd.,  Corporate Center, West Bay Road, P.O. Box 31106, SMD
     Grand Cayman. The address of Castle Creek Partners,  LLC, Mr. Asher and Mr.
     Ziegelman is 333 West Wacker Drive, Chicago, IL 60606.

(6)  Does  include  warrants to purchase  500,0000  shares of Common  Stock at a
     price of $2.67 per share because such warrants are not  exercisable  within
     60 days of July 14,  1998.  Pursuant to the terms of the Series C Preferred
     Stock, no holder thereof can convert or exercise any portion of such Series
     C  Preferred  Stock  if  such  conversion   would  increase  such  holder's
     beneficial ownership of Common Stock to in excess of 4.9%.  Therefore,  for
     purposes of calculating  the number of shares of Common Stock  beneficially
     owned by the Selling Stockholder holding the Series C Preferred Stock, such
     number of shares is assumed to be 4.9% of the outstanding  shares of Common
     Stock, or 1,817,222 shares. Absent such limitation, the number of shares of
     Common Stock issuable upon the conversion of the Series C Preferred  Stock,
     based on a  conversion  price of $2.28,  which is  derived  from 90% of the
     lowest  trading  price of the Common  Stock as of July 7, 1998,  would have
     been 2,192,982  shares or 5.9% of the  outstanding  shares of Common Stock.
     Moreover,  pursuant  to the  regulations  of the  National  Association  of
     Securities Dealers, in the absence of shareholder  approval,  the aggregate
     number of shares of Common Stock  issuable at a discount  from market price
     upon  conversion  of the Series C Preferred  Stock may not exceed 19.99% of
     the  outstanding  shares of Common Stock.  Unless  shareholder  approval is
     obtained to issue  Common  Stock in excess of the maximum  amount set forth
     above,  the holder of the Series C Preferred  Stock will not be entitled to
     acquire  more than its  proportionate  share of such  maximum  amount.  Any
     Series  C  Preferred  Stock  which  may not be  converted  because  of such
     limitation must be redeemed by the Company.

(7)  The  number  of  shares  of  Common  Stock   registered   pursuant  to  the
     Registration  Statement on behalf of the Selling Stockholder holding Series
     C Preferred  Stock and the number of shares of Common Stock offered  hereby
     by such holder have been  determined  by agreement  between the Company and
     such Selling Stockholder. Because the number of shares of Common Stock that
     will  ultimately be issued upon  conversion of the Series C Preferred Stock
     is dependent,  subject to certain limitations,  upon the average of certain
     closing bid prices of the Common  Stock prior to  conversion,  as described
     above,  and  certain  antidilution  adjustments,  such  number of shares of
     Common Stock (and  therefore  the number of shares of Common Stock  offered
     hereby) cannot be determined at this time.  The 6,000,000  shares of Common
     Stock being  registered for the conversion of the Series C Preferred  Stock
     represents  approximately 13% of the Company's currently outstanding shares
     of Common Stock.
    

                                       18

<PAGE>



                               RECENT DEVELOPMENTS

     On January 1, 1998,  Robert  Cook was  appointed  to the  position  of Vice
President-  Finance and Chief Financial Officer.  Prior to joining Pharmos,  Mr.
Cook was Vice  President in the  Healthcare  Group of General  Electric  Capital
Corporation's  Commercial Finance unit, working with pharmaceutical companies as
well as  middle-market  and  emerging  companies.  Prior to  working  at General
Electric, Mr. Cook was at Chase Manhattan Bank for 18 years.

     On  March  10,   1998,   the   Company,   together   with   Bausch  &  Lomb
Pharmaceuticals,  Inc.  ("BLP")  announced the recent approval from the Food and
Drug  Administration  ("FDA")  to  manufacture  and  market  its  two  opthalmic
products,  Lotemax  (loteprednol  etabonate opthalmic suspension 0.5%) and Alrex
(loteprednol etabonate opthalmic suspension 0.2%).

     Lotemax  is a  topical,  site-specific  steroid  that will be used to treat
post-operative  eye  inflammation  such as that experienced  following  cataract
surgery.  The new  prescription  eye drop  will also be used for  various  other
inflammatory eye conditions.  The novel chemical  structure of Lotemax allows it
to be predictably  transformed by enzymes in the eye to an inactive  metabolite,
and increases its safety profile. The safety profile of Lotemax was demonstrated
in clinical  trials by a low  incidence of  increased  intraocular  pressure,  a
significant  side effect of  ophthalmic  steroid use. In addition,  Lotemax will
have the broadest range of indications of any ophthalmic steroid on the market.

     Alrex is a specially  developed formula of loteprednol  etabonate that will
be used in the  treatment of  ophthalmic  allergies.  Alrex is indicated for the
treatment  of  seasonal  allergic  conjunctivitis,  an  inflammation  of the eye
usually caused by pollens.  Seasonal allergic  conjunctivitis  produces itching,
tearing,  redness and swelling in the conjunctiva,  the membrane that covers the
inside of the eyelid and the white part of the eye.


                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

     The  following  documents  filed by the  Company  with the  Commission  are
incorporated herein by reference:

   
     (a) The  Company's  Annual Report on Form 10-K, as amended by Amendment No.
1, dated May 14, 1998,  Amendment No.2, dated July 13, 1998 and Amendment No. 3,
dated July 14, 1998, for the fiscal year ended December 31, 1997, filed pursuant
to Section 13 of the Exchange Act.
    

     (b) The  Company's  Quarterly  Report on Form 10-Q,  for the quarter  ended
March 31, 1998, filed pursuant to Section 13 of the Exchange Act.

     (c)  The  description  of the  Common  Stock  contained  in  the  Company's
Registration  Statement on Form 8-A dated  January 30, 1984,  filed  pursuant to
Section 12 of the Exchange Act.

     (d) The  Company's  Current  Report on Form  8-K,  including  the  exhibits
thereto, dated February 4, 1998.

                                       19

<PAGE>


         (e) The Company's Current Report on Form 8-K, dated March 10, 1998.

     In  addition,  all reports and other  documents  to be filed by the Company
pursuant to Sections  13(a),  13(c),  14 and 15(d) of the Exchange Act, prior to
the filing of a  post-effective  amendment  which  indicates that all securities
offered hereby have been sold or which deregisters all securities offered hereby
then remaining  unsold,  as well as all such reports filed after the date hereof
and  prior  to  the  termination  of  this  offering,  shall  be  deemed  to  be
incorporated  by  reference  herein and shall be deemed to be a part hereof from
the date of the filing of each such report or document.


                     COMMISSION'S POLICY ON INDEMNIFICATION
                         FOR SECURITIES ACT LIABILITIES

     Article 12 of the Company's Restated Articles of Incorporation  directs the
Company to provide in its bylaws for provisions  relating to the indemnification
of directors  and officers to the full extent  permitted by law,  including  the
federal  securities  law.  Section  78.751 of the Nevada  Revised  Statutes,  as
amended,  authorizes  the Company to  indemnify  any  director or officer  under
certain  prescribed  circumstances  and subject to certain  limitations  against
certain costs and expenses,  including  attorneys'  fees actually and reasonably
incurred in  connection  with any action,  suit or  proceeding,  whether  civil,
criminal,  administrative or  investigative,  to which such person is a party by
reason of being a director  or officer of the Company if it is  determined  that
such person  acted in  accordance  with the  applicable  standard of conduct set
forth in such statutory  provisions.  The Company may also purchase and maintain
insurance  for the benefit of any director or officer which may cover claims for
which the Company could not indemnify such person.

     Insofar as  indemnification  for  liabilities  arising under the Act may be
permitted to directors,  officers, and controlling persons of the Company, or to
underwriters (or controlling  persons thereof) of which an officer,  partner, or
controlling  person  thereof is one of the  foregoing  pursuant to the foregoing
provisions or otherwise, the Company has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public policy
as expressed in the Act and is,  therefore,  unenforceable.  In the event that a
claim for  indemnification  against such liabilities  (other than the payment by
the Company of expenses incurred or paid by any such persons,  in the successful
defense of any action,  suit or  proceeding)  is asserted by any such persons in
connection with the securities being registered, the Company will, unless in the
opinion of its counsel  the matter has been  settled by  controlling  precedent,
submit to a court of  appropriate  jurisdiction  the  question  of whether  such
indemnification  by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.


                                       20

<PAGE>




                                 LEGAL OPINIONS

     Legal matters in connection  with the securities  being offered hereby will
be passed upon for the Company by Ehrenreich  Eilenberg  Krause & Zivian LLP, 11
East 44th Street, 17th Floor, New York, NY 10017.

                                     EXPERTS

   
     The financial  statements  incorporated  in this Prospectus by reference to
the Annual Report on Form 10-K for the year ended  December 31, 1997,  have been
so  incorporated  in  reliance  on the  report  of  PricewaterhouseCoopers  LLP,
independent  accountants,  given on the  authority  of said firm as  experts  in
auditing and accounting.
    

                                       21

<PAGE>


                               PHARMOS CORPORATION

                                     , 1998



                                      INDEX



                                                                        Page No.
                                                                        --------


THE COMPANY.................................................................  1

RISK FACTORS................................................................  1

DILUTION ................................................................... 11

USE OF PROCEEDS............................................................. 11

DESCRIPTION OF SECURITIES................................................... 12

PLAN OF DISTRIBUTION........................................................ 15

SELLING SECURITY HOLDERS.................................................... 17

RECENT DEVELOPMENTS......................................................... 19

INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE............................. 19

COMMISSION'S POLICY ON INDEMNIFICATION
FOR SECURITIES ACT LIABILITIES.............................................. 20

LEGAL OPINIONS.............................................................. 21

EXPERTS  ................................................................... 21





<PAGE>



                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

Item 14. Other Expenses of Issuance and Distribution

     The following  statement  sets forth the  estimated  expenses in connection
with the offering described in the Registration  Statement,  assuming all of the
Warrants are exercised at their respective  exercise price (all of which will be
borne by the Registrant).


Securities and Exchange Commission Fee                     $ 6,728
Printing and Engraving Expenses                                100
Accountants' Fees and Expenses                               3,000
Legal Fees and Expenses                                     60,000
Blue Sky Filing Fees                                         1,500
Miscellaneous                                                  672
                                                           -------

TOTAL                                                      $72,000
                                                           =======

Item 15. Indemnification of Directors and Officers.

     Article 12 of the  Registrant's  Certificate of  Incorporation  directs the
Registrant   to  provide  in  its  bylaws  for   provisions   relating   to  the
indemnification  of directors and officers to the full extent  permitted by law.
Section  78.751 of the Nevada  Revised  Statutes,  as  amended,  authorizes  the
Registrant  to  indemnify  any  director  or officer  under  certain  prescribed
circumstances  and  subject to certain  limitations  against  certain  costs and
expenses,   including  attorneys'  fees  actually  and  reasonably  incurred  in
connection  with  any  action,  suit or  proceeding,  whether  civil,  criminal,
administrative  or  investigative,  to which such person is a party by reason of
being a director  or officer of the  Registrant  if it is  determined  that such
person acted in accordance with the applicable  standard of conduct set forth in
such statutory provisions.

     The Registrant may also purchase and maintain  insurance for the benefit of
any director or officer  which may cover claims for which the  Registrant  could
not indemnify such person.

Item 16. Exhibits

     4(a)     Specimen of Common Stock Certificate (incorporated by reference to
              Form S-3 Registration  Statement of the Company dated November 25,
              1994 [No. 33-86720])

     4(b)     Restated  Articles of Incorporation  (incorporated by reference to
              Appendix E to the Joint Proxy  Statement/  Prospectus  included in
              the

                                      II-1

<PAGE>



              Form S-4 Registration Statement of the Registrant dated  September
              28, 1992 [No. 33-52398])

     4(c)     Certificate  of  Amendment of Restated  Articles of  Incorporation
              (incorporated  by reference to the Company's Annual Report on Form
              10- K for the year ended December 31, 1994 [No. 0-11550])

     *4(d)    Certificate  of  Amendment of Restated  Articles of  Incorporation
              dated January 16, 1998

     4(e)     Certificate of Designation,  Rights, Preferences and Privileges of
              Series A Preferred Stock of the Company (incorporated by reference
              to Form S-3  Registration  Statement of the Company dated December
              20, 1996 [No. 333-15165])

     4(f)     Certificate of Designation,  Rights, Preferences and Privileges of
              Series B Preferred Stock of the Company (incorporated by reference
              to Form S-3 Registration  Statement of the Company dated April 30,
              1997 [No. 333- 26155

     4(g)     Certificate of Designation,  Rights, Preferences and Privileges of
              Series C Convertible  Preferred Stock of the Company (incorporated
              by reference to the Company's  Current Report on Form 8-K filed on
              February 4, 1998)

     4(h)     Amended and Restated  By-Laws  (incorporated  by reference to Form
              S-1 Registration Statement of the Company dated June 30, 1994 [No.
              33- 80916])

     4(i)     Form of Stock Securities  Purchase  Agreement dated as of February
              4, 1998  between  the Company and the  Investor  (incorporated  by
              reference  to the  Company's  Current  Report on Form 8-K filed on
              February 4, 1998)

     4(j)     Form of Stock  Purchase  Warrant  dated  as of  February  4,  1998
              between  the  Company  and the  Investor  and the  Company and the
              Placement  Agent  (incorporated  by  reference  to  the  Company's
              Current Report on Form 8- K filed on February 4, 1998)

     *4(k)    Form of Stock Purchase  Warrant dated as of March 31, 1997 between
              the Company and the Investor

     *5       Opinion re: legality


                                      II-2

<PAGE>



     23(a)    Consent of Ehrenreich  Eilenberg  Krause & Zivian LLP (included in
              the Opinion filed as Exhibit 5)

     **23(b)  Consent of PricewaterhouseCoopers LLP

- ---------------

*    Filed with the original S-3 Registration Statement filed on March 5, 1998.

**   Filed herewith.

Item 17. Undertakings.

     The undersigned Registrant hereby undertakes;

     (1) To file,  during any period in which  offers or sales are being made, a
post-effective amendment to this registration statement:

          (i) To include  any  prospectus  required  by section  10(a)(3) of the
     Securities Act of 1933;

          (ii) To reflect in the  prospectus  any facts or events  arising after
     the  effective  date of the  registration  statement  (or the  most  recent
     post-effective amendment thereof) which,  
individually or in the aggregate,
     represent  a  fundamental  change  in  the  information  set  forth  in the
     registration statement;

          (iii) To include any material  information with respect to the plan of
     distribution not previously disclosed in the registration  statement or any
     material change to such information in the registration statement.

     Provided,  however,  that Paragraphs (i) and (ii) above do not apply if the
Registration  Statement  is on  Form  S-3  and the  information  required  to be
included in a  post-effective  amendment  by those  paragraphs  is  contained in
periodic reports filed by the registrant pursuant to Section 13 or Section 15(d)
of the Securities Exchange Act of 1934 that are incorporated by reference in the
Registration Statement.

     (2) That, for the purpose of determining any liability under the Securities
Act of 1933,  each  such  post-effective  amendment  shall be deemed to be a new
registration  statement  relating to the  securities  offered  therein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

     (3) To remove from registration by means of a post-effective  amendment any
of the securities being registered which remain unsold at the termination of the
offering.

     (4) That, for the purpose of determining any liability under the Securities
Act of 1933, each filing of the  registrant's  annual report pursuant to Section
13(a) or 15(d) of the Securities  Exchange Act of 1934 (and,  where  applicable,
each filing of an employee benefit plan's annual

                                      II-3

<PAGE>



report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is
incorporated by reference in the registration  statement shall be deemed to be a
new registration  statement relating to the securities offered therein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

     Insofar as indemnification for liabilities arising under the Securities Act
of 1933 may be permitted to directors,  officers and controlling  persons of the
Registrant pursuant to the foregoing  provisions,  or otherwise,  the Registrant
has been advised that in the opinion of the Securities  and Exchange  Commission
such  indemnification  is against  public policy as expressed in the Act and is,
therefore  unenforceable.  In the event that a claim for indemnification against
such liabilities  (other than the payment by the Registrant of expenses incurred
or paid by a director,  officer,  or controlling person of the Registrant in the
successful  defense of any  action,  suit or  proceeding)  is  asserted  by such
director,  officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction the question whether such  indemnification  by it is against public
policy as expressed in the Act and will be governed by the final adjudication of
such issue.

                                      II-4

<PAGE>


                                   SIGNATURES

   
     Pursuant to the  requirements of the Securities Act of 1933, the registrant
certifies  that it has  reasonable  grounds to believe  that it meets all of the
requirements  for  filing  on Form S-3 and has  duly  caused  this  registration
statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of Iselin  and  State of New  Jersey on the 13th day of
July, 1998.
    

                               PHARMOS CORPORATION

                                      By: /s/      Dr. Haim Aviv          
                                          ----------------------------------
                                          Dr. Haim Aviv, Chairman, Chief
                                          Scientist, Chief Executive Officer
                                          and Director (Principal Executive
                                          Officer)

Pursuant to the  requirements of the Securities Act of 1933,  this  registration
statement or amendment  has been signed  below by the  following  persons in the
capacities and on the dates indicated:

<TABLE>
<CAPTION>
   

Signature                            Title                                             Date
- ---------                            -----                                             ----
<S>                                  <C>                                             <C> 
/s/ Robert Cook                      Chief Financial Officer (Principal              July 13, 1998
- ----------------------------         Financial and Accounting Officer)
Robert Cook                          

/s/ Dr. Gad Riesenfeld               President, Chief Operating Officer              July 13, 1998
- ----------------------------         and Acting Secretary
Dr. Gad Riesenfeld                  

/s/ Marvin P. Loeb                   Director                                        July 13, 1998
- ----------------------------
Marvin P. Loeb

/s/ E. Andrews Grinstead III         Director                                        July 13, 1998
- ----------------------------
E. Andrews Grinstead III

/s/ Stephen C. Knight                Director                                        July 13, 1998
- ----------------------------
Stephen C. Knight

/s/ David Schlachet                  Director                                        July 13, 1998
- ----------------------------
David Schlachet

/s/ Fredric D. Price                 Director                                        July 13, 1998
- ----------------------------
Fredric D. Price

/s/ Mony Ben Dor                     Director                                        July 13, 1998
- ----------------------------
Mony Ben Dor
    
</TABLE>


                                      II-5


                                                                   Exhibit 23(b)



                       CONSENT OF INDEPENDENT ACCOUNTANTS



To the Board of Directors and
Shareholders of Pharmos Corporation

We  hereby  consent  to  the   incorporation  by  reference  in  the  Prospectus
constituting part of this Registration Statement on Form S-3 of our report dated
March 16, 1998 appearing in Pharmos Corporation's Annual Report on Form 10-K for
the year ended  December 31, 1997.  We also consent to the reference to us under
the heading "Experts" in such Prospectus.



/s/PRICEWATERHOUSECOOPERS LLP

PRICEWATERHOUSECOOPERS LLP
New York, New York
July 9, 1998




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