BIOGEN INC
DEF 14A, 1994-05-04
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1
 
                                  SCHEDULE 14A
                                 (RULE 14A-101)
                    INFORMATION REQUIRED IN PROXY STATEMENT
                            SCHEDULE 14A INFORMATION
          PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES
                 EXCHANGE ACT OF 1934 (AMENDMENT NO.          )
 
     Filed by the registrant /X/
     Filed by a party other than the registrant / /
     Check the appropriate box:
     / / Preliminary proxy statement
     /X/ Definitive proxy statement
     / / Definitive additional materials
     / / Soliciting material pursuant to Rule 14a-11(c) or Rule 14a-12
 
                                  BIOGEN, INC.
                (Name of Registrant as Specified in Its Charter)
 
                   ANNE MARIE COOK, ASSISTANT GENERAL COUNSEL
                   (Name of Person(s) Filing Proxy Statement)

Payment of filing fee (Check the appropriate box):
     /X/ $125 per Exchange Act Rule 0-11(c)(1)(ii), 14a-6(i)(1), or 14a-6(j)(2).
     / / $500 per each party to the controversy pursuant to Exchange Act Rule
         14a-6(i)(3).
     / / Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and
         0-11.
 
     (1) Title of each class of securities to which transaction applies:
 
- --------------------------------------------------------------------------------
     (2) Aggregate number of securities to which transactions applies:
 
- --------------------------------------------------------------------------------
     (3) Per unit price or other underlying value of transaction computed
pursuant to Exchange Act Rule 0-11:1
 
- --------------------------------------------------------------------------------
     (4) Proposed maximum aggregate value of transaction:
 
- --------------------------------------------------------------------------------
     / / Check box if any part of the fee is offset as provided by Exchange Act
Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid
previously. Identify the previous filing by registration statement number, or
the form or schedule and the date of its filing.
 
     (1) Amount previously paid:
 
- --------------------------------------------------------------------------------
     (2) Form, schedule or registration statement no.:
 
- --------------------------------------------------------------------------------
     (3) Filing party:
 
- --------------------------------------------------------------------------------
     (4) Date filed:
 
- --------------------------------------------------------------------------------
- ---------------
    1Set forth the amount on which the filing fee is calculated and state how it
was determined.
<PAGE>   2
 
[BIOGEN LOGO]
 
Notice of 1994 Annual Meeting
and Proxy Statement
                                 [PHOTOGRAPH]
<PAGE>   3
- --------------------------------------------------------------------------------
 
[BIOGEN LOGO]
 
                                                                  April 18, 1994
 
Dear Stockholder:
 
     You are cordially invited to attend the 1994 Annual Meeting of Stockholders
of Biogen, Inc. to be held at 10:00 a.m. on Friday, June 3, 1994, at the Royal
Sonesta Hotel, 5 Cambridge Parkway, Cambridge, Massachusetts.
 
     At the Annual Meeting, four persons will be elected to the Board of
Directors. The Board of Directors recommends the re-election of the nominees
named in the Proxy Statement. In addition, the Company will ask the stockholders
to ratify the selection of Price Waterhouse as the Company's independent
accountants for the fiscal year ended December 31, 1994.
 
     Whether or not you plan to attend the Annual Meeting, it is important that
you promptly fill out, sign, date and return the enclosed proxy card in
accordance with the instructions set forth on the card. This will ensure your
proper representation at the Annual Meeting.
 
                                            Sincerely,
 
                                            /s/ JAMES L. VINCENT
 
                                            James L. Vincent
                                            Chairman and Chief Executive Officer
 
     YOUR VOTE IS IMPORTANT. PLEASE REMEMBER TO RETURN YOUR PROXY PROMPTLY.
<PAGE>   4
 
                                  BIOGEN, INC.
 
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD ON JUNE 3, 1994
 
TO THE STOCKHOLDERS OF BIOGEN, INC.
 
     NOTICE IS HEREBY GIVEN that the Annual Meeting of Stockholders of Biogen,
Inc., a Massachusetts corporation, will be held on Friday, June 3, 1994, at the
Royal Sonesta Hotel, 5 Cambridge Parkway, Cambridge, Massachusetts 02142 at
10:00 a.m. for the following purposes:
 
          1. To elect four members to the Board of Directors, three of such
     members to serve for a three-year term ending at the Annual Meeting of
     Stockholders in 1997 and until their successors are duly elected and
     qualified or their earlier resignation or removal and one of such members
     to serve for a two-year term ending at the Annual Meeting of Stockholders
     in 1996 and until his successor is duly elected and qualified or his
     earlier resignation or removal.
 
          2. To ratify the selection of Price Waterhouse as the Company's
     independent accountants for the fiscal year ended December 31, 1994.
 
          3. To transact such other business as may be properly brought before
     the Meeting and any adjournments thereof.
 
     The Board of Directors has fixed the close of business on April 7, 1994 as
the record date for the determination of stockholders entitled to notice of and
to vote at the Meeting and at any adjournments thereof.
 
     All stockholders are cordially invited to attend the Meeting. However, to
ensure your representation you are requested to complete, sign, date and return
the enclosed proxy as soon as possible in accordance with the instructions on
the proxy card. A return addressed envelope is enclosed for your convenience.
 
                                          BY ORDER OF THE BOARD OF DIRECTORS
 
                                          /s/JAMES L. VINCENT

                                          JAMES L. VINCENT
                                          Chairman of the Board
 
Cambridge, Massachusetts
April 18, 1994
<PAGE>   5
 
                                  BIOGEN, INC.
                              14 CAMBRIDGE CENTER
                         CAMBRIDGE, MASSACHUSETTS 02142
                                 (617) 252-9200
 
                                PROXY STATEMENT
 
                              GENERAL INFORMATION
 
     This Proxy Statement is furnished in connection with the solicitation by
the Board of Directors of Biogen, Inc., a Massachusetts corporation (the
"Company"), of proxies to be used at the Annual Meeting of Stockholders to be
held at the Royal Sonesta Hotel, 5 Cambridge Parkway, Cambridge, Massachusetts
on Friday, June 3, 1994 at 10:00 a.m., and any adjournments thereof (the
"Meeting").
 
     If the stockholder specifies a choice on the proxy as to how his or her
shares are to be voted on a particular matter, the shares will be voted
accordingly. If no choice is specified, the shares will be voted FOR the
election of the nominees for Director named herein and FOR ratification of the
selection of Price Waterhouse as the Company's independent accountants. A proxy
may be revoked by written instrument delivered to the Secretary of the Company
at any time before the proxy is voted. Any stockholder who has executed a proxy
but is present at the Meeting, and who wishes to vote in person, may do so by
revoking his or her proxy as described in the preceding sentence.
 
     The close of business on April 7, 1994 has been fixed as the record date
for determining the stockholders entitled to notice of and to vote at the
Meeting. As of the close of business on April 7, 1994, the Company had
32,415,002 shares of Common Stock outstanding and entitled to vote. Abstentions
and broker non-votes are each included as shares present and voting for purposes
of determining whether a quorum is present at the Meeting. Holders of Common
Stock are entitled to one vote per share on all matters to be voted on by the
stockholders, with abstentions and broker non-votes having no effect on the
vote. An automated system administered by the Company's transfer agent tabulates
the votes.
 
     This Proxy Statement and the accompanying proxy are being mailed on or
about April 18, 1994 to all stockholders entitled to notice of and to vote at
the Meeting.
 
                             ELECTION OF DIRECTORS
 
     The Articles of Organization and By-Laws of the Company provide for the
Company's business to be managed by or under the direction of the Board of
Directors, with the advice of the Scientific Board with respect to scientific
and technological matters.
 
     The Board of Directors is classified into three classes serving staggered
three-year terms. Alexander G. Bearn, Harold W. Buirkle and James L. Vincent are
nominees for election at the Meeting for a three-year term ending at the Annual
Meeting of Stockholders in 1997 and until their successors are duly elected and
qualified. Phillip A. Sharp is a nominee for election at the Meeting for a
two-year term ending at the Annual Meeting of Stockholders in 1996 and until his
successor is duly elected and qualified. Alan Belzer, Kenneth Murray and James
W. Stevens constitute a class of Directors with a term ending at the Annual
Meeting of Stockholders in 1995. Roger H. Morley and James R. Tobin constitute a
class of Directors with a term ending at the Annual Meeting of Stockholders in
1996, which class will also include Dr. Sharp upon his election. Mr. Tobin was
elected to the Board of Directors in March 1994 upon commencement of his
employment as President and Chief Operating Officer of the Company. Under the
By-Laws, the number of Directors is fixed from time to time by the Board of
Directors. The Board has fixed the number of Directors at nine.
 
                                        1
<PAGE>   6
 
     Unless authority to vote for the nominees named above is withheld, the
shares represented by the enclosed proxy will be voted FOR the election as
Director of such nominees. In the event that any nominee shall become unable or
unwilling to accept nomination or election, the shares represented by the
enclosed proxy will be voted for the election of such other person as the Board
of Directors may recommend in his place. The Board of Directors has no reason to
believe that any nominee will be unable or unwilling to serve.
 
     The following information is furnished with respect to the Directors of the
Company:
 
<TABLE>
<CAPTION>
  NAME, AGE AND YEAR                        PRINCIPAL OCCUPATION DURING PAST
FIRST BECAME A DIRECTOR                     FIVE YEARS; OTHER DIRECTORSHIPS
- -----------------------   --------------------------------------------------------------------
<S>                       <C>
- ----------------          Visiting Physician, Adjunct Professor at the Rockefeller University
                          in New York since 1966 and Trustee of the Rockefeller University
[Alexander G. Bearn       since 1970; Trustee of Howard Hughes Medical Institute since 1987;
      Photo]              from 1979 to 1988 Senior Vice President for Medical and Scientific
- ----------------          Affairs of the International Division of Merck & Co.; prior to
Alexander G. Bearn,       joining Merck, the first Stanton Griffis Distinguished Medical
M.D.* (age 71)            Professor at Cornell University Medical College; from 1966 to 1977,
1991                      Chairman of the Department of Medicine at Cornell University Medical
NOMINEE FOR RE-ELECTION   College; member of the Scientific Board of the Company.


- ----------------          President, Chief Operating Officer and Director, Allied-Signal, Inc.
                          from 1988 to 1993; from 1983 to 1988, Executive Vice President and
[Alan Belzer              President, Engineered Materials Sector, Allied-Signal, Inc.
   Photo]       
- ----------------
Alan Belzer
(age 61)
1990


- ----------------          Managing Director, The Henley Group, Inc. from 1986 to 1990; from
                          1983 to 1985, Executive Vice President, Finance and Planning, Allied
[Harold W. Buirkle        Corporation (now Allied-Signal, Inc.); and from 1981 to 1983, Senior
     Photo]               Vice President -- Planning and Finance of Allied Corporation.
- ----------------
Harold W. Buirkle
(age 73)
1986
NOMINEE FOR RE-ELECTION
</TABLE>
 
                                        2
<PAGE>   7
<TABLE>
<CAPTION>
  NAME, AGE AND YEAR                        PRINCIPAL OCCUPATION DURING PAST
FIRST BECAME A DIRECTOR                     FIVE YEARS; OTHER DIRECTORSHIPS
- -----------------------   --------------------------------------------------------------------
<S>                       <C>
- ----------------          Vice President, Schiller International University, Heidelberg,
                          Germany since 1983; Director of Continental Bank and Continental
[Roger H. Morley          Corporation; Director of Artal, S.A., Luxembourg; Co-Managing
     Photo]               Director, R&R Inventions Ltd., Birmingham, U.K.; from 1974 to 1984,
- ----------------          a Director of Western Electric Company, Inc.; from 1975 to 1980, a
Roger H. Morley           Director of American Express Company; from 1978 to 1985, a Director
(age 62)                  of Allied Corporation; from 1982 to 1986 a Director of Converse Inc;
1987                      and from 1986 to 1990, a Director of Shafer Value Trust.


- ----------------          Biogen Professor of Molecular Biology, University of Edinburgh,
                          Scotland since 1984; during 1985 and 1986, Interim Research Director
[Kenneth Murray           of Biogen S.A; from 1976 to 1984, Professor and Head of the
    Photo]                Department of Molecular Biology, University of Edinburgh; Fellow of
- ----------------          the Royal Society; Vice Chairman of the Scientific Board of the
Kenneth Murray, Ph.D.*    Company.
(age 63)
1980


- ----------------          Salvador E. Luria Professor and Head of the Department of Biology,
                          Center for Cancer Research, Massachusetts Institute of Technology
[Phillip A. Sharp         since 1991; Director of the Center for Cancer Research at MIT from
     Photo]               1985 to 1991; Chairman of the Scientific Board of the Company.
- ----------------
Phillip A. Sharp,
  Ph.D.*
(age 49)
1982
NOMINEE FOR RE-ELECTION
</TABLE>
 
                                        3
<PAGE>   8
<TABLE>
<CAPTION>
  NAME, AGE AND YEAR                        PRINCIPAL OCCUPATION DURING PAST
FIRST BECAME A DIRECTOR                     FIVE YEARS; OTHER DIRECTORSHIPS
- -----------------------   --------------------------------------------------------------------
<S>                       <C>
- ----------------          Chairman, Prudential Asset Management Group since 1993; Executive
                          Vice President, The Prudential Insurance Company of America and
[James W. Stevens         Prudential Investment Corporation from 1987 to 1993; Managing
     Photo]               Director, Dillon, Read & Company Inc. from 1985 until 1987; from
- ----------------          1984 until April 1985, Group Executive of Citicorp and Citibank N.A.
James W. Stevens          and Chairman of Citicorp Venture Capital, Ltd.; from 1981 until
(age 57)                  1984, Executive Vice President, Merchant Banking Group, Citibank,
1986                      N.A.


- ----------------          President and Chief Operating Officer of Biogen, Inc. since February
                          1994; from 1992 to 1993, President and Chief Operating Officer of
[James R. Tobin           Baxter International; from 1988 to 1992, Executive Vice President of
     Photo]               Baxter International.
- ----------------
James R. Tobin
(age 49)
1994


- ----------------          Chief Executive Officer and Chairman of the Board of Directors of
                          Biogen, Inc. since 1985 and President from 1985 to February 1994;
[James L. Vincent         from 1982 to 1985, Group Vice President, Allied Corporation (now
     Photo]               Allied-Signal, Inc.) and President, Allied Health and Scientific
- ----------------          Products Company; from 1979 through 1980, Executive Vice President,
James L. Vincent          Chief Operating Officer and a Director of Abbott Laboratories, Inc.;
(age 54)                  a Director of Millipore Corporation, Continental Bank and
1985                      Continental Corporation.
NOMINEE FOR RE-ELECTION

<FN> 
- ---------------
* Drs. Bearn, Murray and Sharp were nominated for election to the Board of
  Directors by the Company pursuant to designation by the Scientific Board.
</TABLE>
 
     A plurality of the votes cast at the Meeting is required to elect each
nominee as a Director.
 
THE BOARD OF DIRECTORS RECOMMENDS ELECTION OF MESSRS. BEARN, BUIRKLE, SHARP AND
VINCENT AS DIRECTORS.
 
                                        4
<PAGE>   9
 
                       BOARD OF DIRECTORS AND COMMITTEES
 
GENERAL
 
     During 1993 there were five meetings of the Board of Directors. The Board
has four committees. The Compensation and Management Resources Committee, which
met four times during 1993, has four members, James W. Stevens (Chairman), Roger
H. Morley, Phillip A. Sharp and James L. Vincent. The Compensation and
Management Resources Committee makes recommendations to the Board concerning
remuneration and benefits for senior executives, and reviews executive
development and succession. The Finance and Audit Committee, which met four
times during 1993, has three members, Harold W. Buirkle (Chairman), Alan Belzer
and Roger H. Morley. The Finance and Audit Committee reviews the Company's
quarterly and annual financial statements and Annual Report on Form 10-K,
considers matters relating to accounting policy and internal controls, reviews
the scope of annual audits, recommends independent public accountants to the
Board and makes recommendations concerning financial, investment and taxation
policies. The Project Share Committee, whose members are Phillip A. Sharp
(Chairman), Kenneth Murray and James L. Vincent, recommends to the Board stock
and stock option awards for scientific consultants with respect to work
undertaken by them for the Company and decides whether predetermined goals have
been achieved to permit vesting of such stock or stock option rights. The
Project Share Committee did not meet during 1993. The Stock and Option Plan
Administration Committee, which met four times during 1993, has two members,
Roger H. Morley and James W. Stevens. The Stock and Option Plan Administration
Committee administers certain stock and stock option plans and approves stock
and stock option awards. The Company has no standing nominating committee.
 
     No incumbent Director attended fewer than 75% of the total number of
meetings of the Board and of Committees of the Board on which he served during
1993.
 
COMPENSATION OF DIRECTORS
 
     Non-employee members of the Company's Board of Directors are entitled to
receive $1,500 for each Board meeting attended, and $500 for attending each
meeting of Committees of the Board on which they serve, except for Committee
chairmen, who receive $1,000 per Committee meeting attended. Those Directors who
are members of the Company's Scientific Board and who are not Company employees
also receive an annual consulting fee of $15,000, $1,500 per day for Scientific
Board meetings, and $500 per day for each full working day spent in the
Company's laboratories, except for the Chairman of the Scientific Board whose
annual consulting fee is $60,000.
 
     Directors are eligible to participate in the Company's 1985 Non-Qualified
Stock Option Plan (the "1985 Plan"). During the fiscal year ended December 31,
1993, the Company granted to Mr. Belzer an option to purchase 21,000 shares of
Common Stock under the 1985 Plan. Directors who are also members of the
Company's Scientific Board are eligible to participate in the Company's 1987
Scientific Board Stock Option Plan.
 
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
 
     The Compensation and Management Resources Committee which determines cash
remuneration and benefits for senior executives and reviews executive
development and succession has four members, James W. Stevens (Chairman), Roger
H. Morley, Phillip A. Sharp and James L. Vincent, the Chairman of the Board and
Chief Executive Officer of the Company.
 
                                        5
<PAGE>   10
<TABLE>
                                SHARE OWNERSHIP
 
     The following table sets forth information as of March 21, 1994 concerning
the ownership of Common Stock by each stockholder known by the Company to be the
beneficial owner of more than 5% of its outstanding shares of Common Stock, each
current member of the Board of Directors, each of the executive officers named
in the Summary Compensation Table included in this Proxy Statement and all
current Directors and executive officers as a group. Except as otherwise noted,
the persons or entities identified have sole voting and investment power with
respect to such shares.
 
<CAPTION>
                                                                          SHARES BENEFICIALLY
                                                                                 OWNED
                                                                        ------------------------
                          NAME AND ADDRESS**                             NUMBER       PERCENT(1)
- ----------------------------------------------------------------------  ---------     ----------
<S>                                                                     <C>              <C>
Alexander G. Bearn....................................................     30,100(2)        *
Alan Belzer...........................................................     21,000(3)        *
Harold W. Buirkle.....................................................     78,000(4)        *
Roger H. Morley.......................................................     34,000(3)        *
Kenneth Murray........................................................    268,000(5)        *
Phillip A. Sharp......................................................    256,000(6)        *
James W. Stevens......................................................     57,000(7)        *
James R. Tobin........................................................          0           *
James L. Vincent......................................................    721,963(8)     2.18%
Kenneth M. Bate.......................................................    111,866(9)        *
Irving H. Fox.........................................................     89,764(10)       *
Joseph M. Davie.......................................................     31,250(3)        *
Lawrence S. Daniels...................................................     50,478(11)       *
All executive officers and Directors as a group (19 persons)..........  2,051,866(12)    6.04%
Forstmann-Leff Associates Inc. .......................................  2,543,080(13)    7.85%
  55 East 52nd Street
  New York, NY 10055
New York Life Insurance Company.......................................  1,800,000(14)    5.26%
  51 Madison Avenue
  New York, NY 10010
FMR Corp. ............................................................  1,923,110(15)    5.93%
  82 Devonshire Street
  Boston, MA 02109
The Prudential Insurance Company of America...........................  1,737,800(16)    5.36%
  Prudential Plaza
  Newark, NJ 07102
Jennison Associates Capital Corp. ....................................  1,619,900(17)    5.00%
  466 Lexington Avenue
  New York, NY 10017
- ---------------
<FN> 
 *  Represents beneficial ownership of less than 1% of the Company's outstanding
    shares of Common Stock.
 
**  Addresses are given for beneficial owners of more than 5% of the outstanding
    Common Stock only.
</TABLE>
                                         (Footnotes continued on following page)
 
                                        6
<PAGE>   11
[FN] 
(Footnotes continued from preceding page)
 (1) The calculation of percentages is based upon the number of shares issued
     and outstanding at March 21, 1994, plus shares subject to options held by
     the respective person at March 21, 1994 and which are exercisable on March
     21, 1994 or become exercisable on or before May 20, 1994.
 
 (2) Includes 30,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
 
 (3) Represents shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
 
 (4) Includes 37,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
 
 (5) Includes 43,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
 
 (6) Includes 28,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
 
 (7) Includes 47,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
 
 (8) Includes 719,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994.
     Certain of the shares acquired upon exercise of such options are subject to
     repurchase by the Company under certain circumstances. Includes 963 shares
     acquired as matching contributions under the Company's 401(k) plan. See
     "Executive Compensation -- Summary Compensation Table." Includes 1,500
     shares held by Mr. Vincent's wife and 500 shares held by one of his
     children.
 
 (9) Includes 111,666 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994 and
     200 shares acquired as matching contributions under the Company's 401(k)
     plan.
 
(10) Includes 89,500 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994 and
     264 shares acquired as matching contributions under the Company's 401(k)
     plan.
 
(11) Includes 50,000 shares which may be acquired pursuant to options which are
     currently exercisable or become exercisable on or before May 20, 1994 and
     67 shares acquired as matching contributions under the Company's 401(k)
     plan.
 
(12) Includes 1,536,348 shares which may be acquired pursuant to options which
     are currently exercisable or become exercisable on or before May 20, 1994.
     Does not include shares which may be purchased in 1994 by officers who are
     currently participants in the 1983 Employee Stock Purchase Plan. Includes
     3,579 shares acquired as matching contributions under the Company's 401(k)
     plan.
 
(13) Includes 1,854,720 shares as to which Forstmann-Leff Associates Inc. has
     sole dispositive power, 488,660 shares as to which it shares dispositive
     power with its subsidiary, FLA Asset Management, Inc., and 181,900 shares
     as to which it shares dispositive power with its subsidiary, Stamford
     Advisors Corp., all as reported on Schedule 13G as of December 31, 1993.
     Forstmann-Leff Associates Inc. has sole voting power over 1,375,315 of such
     shares and shares voting power over 88,500 shares with FLA Asset
     Management, Inc., and over 181,900 shares with Stamford Advisors Corp. also
     as reported on
 
                                         (Footnotes continued on following page)
 
                                        7
<PAGE>   12
[FN] 
(Footnotes continued from preceding page)
     Schedule 13G as of December 31, 1993. Includes 17,800 shares as to which
     Forstmann-Leff Associates has voting but no dispositive power.
 
(14) Represents shares that may be acquired upon exercise of currently
     exercisable warrants.
 
(15) FMR Corp. ("FMR") is a parent holding company. Fidelity Management &
     Research Company ("Fidelity"), a wholly-owned subsidiary of FMR Corp., is
     the beneficial owner of 1,718,410 shares as a result of acting as an
     investment adviser to several investment companies and as a subadvisor to
     Fidelity American Special Situations Trust. Fidelity Management Trust
     Company ("FMTC"), a wholly owned subsidiary of FMR, is the beneficial owner
     of 204,700 shares as a result of its serving as an investment manager of
     institutional accounts. FMR Corp. and Edward C. Johnson 3d, through their
     control of Fidelity and FMTC, have sole power to dispose of the shares
     beneficially owned by Fidelity and FMTC and sole power to vote 6,000 of the
     shares beneficially owned by Fidelity and 163,500 of the shares
     beneficially owned by FMTC. The above information was reported on Schedule
     13G as of December 31, 1993.
 
(16) The Prudential Insurance Company of America ("Prudential"), a mutual
     insurance company, may have direct or indirect voting and/or investment
     discretion over 1,737,800 shares which are held for the benefit of its
     clients by its separate accounts, externally managed accounts, registered
     investment companies, subsidiaries and other affiliates. Prudential has
     sole voting and dispositive power as to 219,700 of the shares, shares
     voting power as to 1,188,900 of the shares and shares dispositive power
     over 1,518,100 of the shares. The above information was reported on
     Schedule 13G as of December 31, 1993.
 
(17) Jennison Associates Capital Corp. ("Jennison") is an investment advisor and
     may be deemed the beneficiary owner of the 1,619,900 shares as to which it
     shares dispositive power. Jennison has sole voting power over 305,700 of
     the shares and shares voting power over 985,000 of the shares, as reported
     on Schedule 13G as of December 31, 1993.
 
                                        8
<PAGE>   13
 
                             EXECUTIVE COMPENSATION
 
     The following table sets forth the compensation of the Chief Executive
Officer of the Company (the "CEO") and the four other most highly compensated
executive officers during the three fiscal years ended December 31, 1993.
 
<TABLE>
SUMMARY COMPENSATION TABLE
 
<CAPTION>
                                                                            LONG TERM
                                                                           COMPENSATION
                                           ANNUAL COMPENSATION             ------------
                                -----------------------------------------     SHARES
  NAME AND PRINCIPAL                                      OTHER ANNUAL      UNDERLYING       ALL OTHER
       POSITION          YEAR    SALARY        BONUS   COMPENSATION(1)(2)   OPTIONS(#)   COMPENSATION(2)(3)
- -----------------------  -----  --------     --------- ------------------  ------------  ------------------
<S>                      <C>    <C>          <C>       <C>                 <C>           <C>
James L. Vincent.......   1993  $635,000     $ 310,000      $      0                0         $ 21,139
  Chairman and Chief      1992   570,000       285,000             0          200,000           19,746
  Executive Officer       1991   510,000       255,000           N/A           50,000              N/A
Kenneth M. Bate........   1993   220,000        72,000        25,640           25,000            3,207
  Vice President--        1992   196,000        59,000        28,835           25,000            3,207
  Marketing and Sales     1991   175,000        60,750           N/A           25,000              N/A
Irving H. Fox..........   1993   207,500        50,000        76,667           15,000            4,085
  Vice President--        1992   193,000        46,000        76,667           15,000            3,869
  Medical Affairs         1991   179,000        39,000           N/A           20,000              N/A
Joseph M. Davie........   1993   190,000(4)     75,000        99,987          250,000              892
  Vice President--        1992       N/A           N/A           N/A              N/A              N/A
  Research                1991       N/A           N/A           N/A              N/A              N/A
Lawrence S. Daniels....   1993   180,000(4)     35,000        41,040                0            3,943
  Vice President--        1992   180,000        36,000       149,941           25,000            1,554
  Strategic Planning      1991    14,538             0           N/A          100,000              N/A
 
- ---------------
<FN> 
(1) Other Annual Compensation in 1993 for Dr. Fox represents, and for Mr. Bate
    and Mr. Daniels includes, the portion of payments under a contingent bonus
    and mortgage loan forgiveness program made in connection with their hiring
    which became vested during the last fiscal year in the amount of $76,667,
    $25,556 and $40,000 respectively. Other Annual Compensation for Dr. Davie
    includes $61,834 in relocation expense payments and $32,204 in payments to
    cover taxes on relocation expense reimbursement.
 
(2) Information for 1991 is not required to be included under transition rules.
 
(3) All Other Compensation for Mr. Vincent, Mr. Bate, Dr. Fox and Mr. Daniels
    includes the dollar value of matching contributions made in shares of the
    Company's Common Stock during the last fiscal year under the Company's
    401(k) plan in the amount of $2,182, $2,182, $2,092 and $2,248,
    respectively, and for each of the named individuals also includes the dollar
    value of premiums paid by the Company during the last fiscal year with
    respect to term life insurance for their benefit under an executive life
    insurance program in the amount of $18,957 for Mr. Vincent, $1,025 for Mr.
    Bate, $1,993 for Dr. Fox, $892 for Dr. Davie and $1,695 for Mr. Daniels.
 
(4) Includes compensation only for the period of the year during which the
    individual was employed by the Company.
</TABLE>
                                        9
<PAGE>   14
<TABLE>
OPTION GRANTS IN LAST FISCAL YEAR
 
     The following table sets forth information regarding options granted to the
CEO of the Company and the four other most highly compensated executive officers
during the fiscal year ended December 31, 1993.
 
<CAPTION>
                                     INDIVIDUAL GRANTS                                          POTENTIAL REALIZABLE
- -------------------------------------------------------------------------------------------    VALUE AT ASSUMED ANNUAL
                                    NUMBER OF                                                   RATES OF STOCK PRICE
                                      SHARES       % OF TOTAL                                  APPRECIATION FOR OPTION
                                    UNDERLYING   OPTIONS GRANTED                                       TERM(1)
                                     OPTIONS      TO EMPLOYEES      EXERCISE     EXPIRATION   -------------------------
               NAME                 GRANTED(2)   IN FISCAL YEAR    PRICE($/SH)      DATE        5%($)         10%($)
- ----------------------------------  ----------   ---------------   -----------   ----------   ----------    -----------
<S>                                   <C>             <C>             <C>         <C>          <C>           <C>
James L. Vincent..................          0             0             N/A            N/A           N/A            N/A
Kenneth M. Bate...................     25,000          2.71           40.00       12/09/03       628,895      1,593,743
Irving H. Fox.....................     15,000          1.63           40.00       12/09/03       377,337        956,245
Joseph M. Davie...................    250,000         27.12           27.00        4/12/03     4,245,039     10,757,762
Lawrence S. Daniels...............          0             0             N/A            N/A           N/A            N/A
 
- ---------------
<FN> 
(1) The potential realizable values for all stockholders at the assumed annual
    rates of stock price appreciation of 5% and 10% would be $815,066,856 and
    $2,065,539,442, respectively. These values assume increases in the value of
    the shares of Common Stock outstanding at December 31, 1993 at the stated
    percentages over a ten-year period from an initial value of $40.125, the
    average of the high and low sales prices of the Company's Common Stock on
    December 31, 1993.
 
(2) The options granted to the named executive officers vest annually in six
    equal installments commencing one year from the date of grant, with the
    exception of Dr. Davie's options which vest over seven years.
</TABLE>
<TABLE>
AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR AND YEAR-END OPTION VALUES
 
     The following table sets forth information regarding options exercised by
the CEO and the four other most highly compensated executive officers of the
Company during the fiscal year ended December 31, 1993.
 
<CAPTION>
                                                                NUMBER OF SHARES              VALUE OF UNEXERCISED
                                                             UNDERLYING UNEXERCISED           IN-THE-MONEY OPTIONS
                                                              OPTIONS AT YEAR END                AT YEAR END(1)
                        SHARES ACQUIRED       VALUE       ----------------------------    -----------------------------
         NAME           ON EXERCISE(#)     REALIZED($)    EXERCISABLE    UNEXERCISABLE    EXERCISABLE     UNEXERCISABLE
- ----------------------  ---------------    -----------    -----------    -------------    -----------     -------------
<S>                            <C>              <C>         <C>             <C>           <C>              <C>
James L. Vincent......         0                0           719,000               0       $13,409,660(2)   $         0
Kenneth M. Bate.......         0                0           111,666          98,334         1,858,594          717,969
Irving H. Fox.........         0                0            64,500          70,500           722,082        1,270,098
Joseph M. Davie.......         0                0                 0         250,000                 0        3,281,250
Lawrence S. Daniels...         0                0            45,000          80,000           191,250          490,000
- ---------------
<FN>
(1) The value of unexercised in-the-money options at year-end assumes a fair
    market value for the Company's Common Stock of $40.125, the average of the
    high and low sales prices of the Company's Common Stock on December 31,
    1993.
 
(2) The shares issuable upon exercise of options held by Mr. Vincent are subject
    to repurchase by the Company under certain conditions and for a specified
    period.
</TABLE>

PENSION PLAN
 
     Biogen has a defined benefit pension plan providing a monthly pension for
life beginning at age 65. The current pension benefit formula is the sum of (i)
2% of 1986 compensation times years of service through
 
                                       10
<PAGE>   15
 
October 31, 1986, plus (ii) for each year of service after October 31, 1986,
through December 31, 1988, 1.5% of compensation during the year up to the Social
Security taxable wage base for the year and 2.5% of compensation during the year
in excess of the Social Security taxable wage base, plus (iii) for each year of
service after 1988, 1.6% of compensation during the year up to the participant's
Social Security covered compensation level and 2.2% of compensation during the
year in excess of the participant's Social Security covered compensation level.
Each participant under the plan as in effect before November 1, 1986, will
receive a pension of not less than the value of his or her account balance as of
October 31, 1986, the date at which the plan changed from a defined contribution
to a defined benefit plan, plus interest at the rate of 8%. Such a participant
may elect to receive his or her account balance in a single sum payment upon
termination of employment.
 
     The pension plan covers all U.S. employees of Biogen (other than students
employed on a temporary basis) as of the first day of the calendar quarter
following date of hire. A participant's interest in the plan is subject to a
graded vesting schedule based on years of service with Biogen. Each employee is
fully vested after completing seven years of service.
 
     Effective January 1, 1991, Biogen adopted the Biogen Supplemental Executive
Retirement Plan (the "SERP"). Certain executive officers are eligible to
participate in this plan, which is a non-funded arrangement. The purpose of the
SERP is to maintain for SERP participants the level of retirement benefits
provided under the pension plan's benefit formula before its amendment. The
formula was amended to comply with new requirements enacted by the Tax Reform
Act of 1986, with the amended formula applicable to service rendered starting in
1989. The amended formula (described above) results in a reduction in benefit
accruals for certain executive officers. The SERP benefit formula maintains the
pre-amendment pension plan's level of benefit accruals. The SERP will also serve
as an excess benefit plan to make up for benefits that cannot be paid from the
pension plan because of the limitation contained in the Internal Revenue Code of
1986, as amended, on compensation and benefits under a tax-qualified plan such
as the pension plan.
 
<TABLE>
     The following table shows the total estimated annual benefits payable upon
retirement (age 65) for life under the pension plan and the SERP. These
estimates are based on the assumptions that an employee will continue to work
for Biogen until normal retirement age with no change in current 1993
compensation and that the Social Security taxable wage base in 1994 of $60,600
will continue without change.
 
<CAPTION>
          CURRENT SALARY
            PLUS BONUS                  15           20           25           30            35
- -----------------------------------  ---------    ---------    ---------    ---------    -----------
<S>                                  <C>          <C>          <C>          <C>          <C>
$ 150,000..........................  $  49,000    $  65,000    $  81,000    $  96,000    $   112,000
   200,000.........................     68,000       90,000      112,000      134,000        156,000
   300,000.........................    106,000      140,000      174,000      209,000        243,000
   400,000.........................    143,000      190,000      237,000      284,000        331,000
   500,000.........................    181,000      240,000      299,000      359,000        418,000
   600,000.........................    218,000      290,000      362,000      434,000        506,000
   700,000.........................    256,000      340,000      424,000      509,000        593,000
   800,000.........................    293,000      390,000      487,000      584,000        681,000
   900,000.........................    331,000      440,000      549,000      659,000        768,000
 1,000,000.........................    368,000      490,000      612,000      734,000        856,000
 1,100,000.........................    406,000      540,000      674,000      809,000        943,000
 1,200,000.........................    443,000      590,000      737,000      884,000      1,031,000
</TABLE>
 
                                       11
<PAGE>   16
 
     The (i) current pensionable earnings (salary and bonus), (ii) current years
of service, and (iii) projected total service at age 65 are as follows for each
of the executive officers named in the compensation and option tables: Mr.
Vincent ($945,000 8.5 years, 19 years (projected)); Mr. Bate ($292,000, 3.5
years, 26 years (projected)); Dr. Fox ($257,500, 4 years, 19 years (projected));
Dr. Davie ($265,000, 1.0 years, 11.5 years (projected)) and Mr. Daniels
($215,000, 2.0 years, 16.0 years (projected)).
 
                            EMPLOYMENT ARRANGEMENTS
 
     Each of Mr. Bate, Dr. Fox, Dr. Davie and Mr. Daniels has an agreement with
the Company under which each receives executive life insurance and tax
preparation services. Each of the agreements further provides for compensation
of the officer in the event his employment is terminated by the Company, other
than for cause, in the amount of base salary and certain medical benefits for
twelve months or until alternative employment is obtained, if earlier. Mr.
Vincent also has an agreement with the Company under which he receives term
life, disability, and personal liability insurance, personal income tax return
preparation and tax audit services. Mr. Vincent's agreement with the Company
also provides for yearly salary reviews and a minimum bonus of 25% of base
salary if his performance is satisfactory. In addition, Mr. Vincent will be
entitled to receive the discounted present value of an amount equal to
compensation for 30 months following non-cause termination (whether by the
Company, or in certain cases, by Mr. Vincent) based on his last annual salary
and bonus, together with the amount of certain excise taxes imposed on such
termination payments.
 
                                       12
<PAGE>   17
 
                      STATEMENT OF COMPENSATION PHILOSOPHY
                     (REPORT OF COMPENSATION AND MANAGEMENT
                       RESOURCES COMMITTEE AND STOCK AND
                     OPTION PLAN ADMINISTRATION COMMITTEE)
 
     As our company grows and matures, the capacity and talent of our people are
the most important factors for ensuring long-term vitality. They will make the
critical difference in the future.
 
                                          JAMES L. VINCENT
                                          Message to Stockholders, 1991 Annual
                                          Report
 
     The Biogen executive compensation program consists of four parts: base
salary, annual bonus, stock options, and additional benefits. In developing this
program, the Company's overall compensation philosophy is the critical
underlying element. This philosophy is to hire individuals possessing excellent
professional skills, coupled with outstanding managerial track records, who will
help achieve the Company's mission of moving from a development-stage company to
a global operating pharmaceutical company.
 
     A practical outcome of the philosophy is the Company's continued commitment
to recruit, motivate and retain senior executives with demonstrated talent and
managerial leadership skills typically gained from successful experiences in
positions of greater scope and responsibility in pharmaceutical and other
industry settings. This commitment will enable the Company to have the requisite
management capacity in place to fulfill its stated mission.
 
     Inherent in this philosophy is leveraging the compensation program by
placing a significant emphasis on equity participation. This is accomplished by
offering a capital accumulation opportunity that conserves cash and blends the
interests of stockholders with those of senior management. The Company's target
for total compensation is to be competitive with Fortune 500 pharmaceutical
companies, which typically results in Biogen pay levels at or above the 75th
percentile of the biotechnology industry. In 1993, the total compensation
package paid to executive officers, other than the Chief Executive Officer, was
slightly above average compared to the major biotechnology companies with
respect to cash compensation, and above the 75th percentile of the major
biotechnology companies with respect to the value of stock options granted.
 
     Individual compensation decisions are made with reference to progress
toward goals tailored for a company at Biogen's stage of development, rather
than traditional measures of a company's performance, such as short-term
earnings per share, which often do not relate to the successful execution of a
strategy such as that which Biogen is pursuing at this stage of its development.
 
BASE SALARY
 
     Company philosophy regarding executive base salary is to maintain it at a
competitive level, sufficient to recruit individuals possessing the skills and
values necessary to achieve the Company's vision and mission over the long term.
Determinations of appropriate base salary levels are generally made through
regular participation in a variety of industry and industry-related surveys and
special studies, as well as by monitoring developments in key industries such as
the pharmaceutical industry. This information is also used in evaluating other
compensation elements. Periodic adjustments in base salary will relate to
competitive factors and to individual performance evaluated against
pre-established objectives.
 
                                       13
<PAGE>   18
 
ANNUAL BONUS
 
     The Compensation and Management Resources Committee of the Board, in its
discretion, may award bonuses to executive officers, and the Company expects to
pay bonuses based on each executive officer's performance goals. The intent of
the annual bonus is to motivate and reward performance of senior executives
measured against distinct and clearly articulated goals and in light of the
competitive compensation practices of the biotechnology industry. The goals vary
with each executive officer's responsibilities and are based on milestones to be
accomplished by the officer rather than being fixed by reference to overall
measures of the Company's performance. In 1993, these goals included achievement
of certain clinical milestones with respect to late stage product candidates,
commencement of new facilities construction and closing of related financing and
acquisition or licensing of key technology and patent rights.
 
STOCK OPTIONS
 
     Stock options are viewed as a fundamental element in the total compensation
program and, in keeping with the Company's basic philosophy, emphasize long term
Company performance as measured by creation of stockholder value. Additionally,
the holding of options by senior executives fosters a community of interest
between stockholders and the executives as well as the other participants in the
Company's stock option plans. The Company believes that because of this
community of interest, the use of stock options is preferable to other forms of
stock compensation such as restricted stock. Options under the Company's stock
option plans are granted to almost all employees, and particularly to key
employees who are likely to contribute significantly to the growth and
successful operation of the Company. In determining the size of the grant of an
option to an executive officer in any year, the Company considers not only
competitive factors, changes in responsibility and the executive officer's
achievement of individual pre-established goals, as described above, but also
the number and terms of options previously granted to the officer. In addition,
a significant grant of options is usually made when an executive officer joins
the Company. In 1993, Dr. Davie was granted options to purchase a significant
number of shares in connection with his joining the Company as Vice President --
Research. The size of option grants to executive officers is determined by the
Stock and Option Plan Administration Committee upon recommendation by the Chief
Executive Officer.
 
     Although options may be granted at any price equal to or greater than the
par value of the Common Stock, historically options have been granted, as a
matter of Company policy, at 100% of the fair market value on the date of grant.
The Company has generally awarded options to officers on employment and at
regular intervals thereafter, but awards may be made at other times as well.
Some of the Company's stock option plans also provide for granting options to
members of the Board of Directors and the Scientific Board.
 
     Vesting of stock options is determined by the Board's Stock and Option Plan
Administration Committee. Options granted to employees other than the Chief
Executive Officer vest in periods generally ranging from six to seven years
after grant.
 
ADDITIONAL BENEFITS
 
     The fourth element of Biogen's executive compensation program is the
additional benefit component. Executive officers are entitled to participate in
the benefit plans generally available to employees. In addition executive
officers receive executive life insurance and tax preparation services as
described elsewhere in this Proxy Statement.
 
                                       14
<PAGE>   19
 
CEO COMPENSATION
 
     The compensation of Biogen's Chief Executive Officer reflects the
philosophy described above. Mr. Vincent has had extensive pharmaceutical
industry experience and was hired in 1985 from one of the nation's largest
corporations at a time when Biogen's financial condition and prospects were
considerably weaker. The terms of his employment, which included his initial
stock option grants, were structured to provide significant incentives to
contribute to the Company's success. Under those terms, it was contemplated that
he would receive a base salary that would increase at varying, unspecified rates
depending on inflation and his performance, and an annual bonus computed as a
percentage of base salary based on a minimum bonus of 25% of base salary if his
performance is satisfactory, with a significantly higher bonus contemplated if
his performance is more than satisfactory. Mr. Vincent's employment may be
terminated at any time by him or Biogen. Other details are set forth under
"Employment Arrangements," above.
 
     Mr. Vincent's compensation is not formula based but rather is determined by
the Compensation and Management Resources Committee and the Stock and Option
Plan Administration Committee based on the Committees' assessment of Mr.
Vincent's performance and review of data showing the compensation of Mr.
Vincent's peers in the pharmaceutical industry. Mr. Vincent's performance is
evaluated by the Committees by considering various factors, including the
breadth of Mr. Vincent's responsibilities and progress made in the Company's
development toward becoming a fully integrated pharmaceutical company as
measured by the Committees' assessment of the performance of the key
departments. At each quarterly meeting, the Board receives a status report from
the key departments reviewing achievements and setbacks during the preceding
quarter and detailing plans for the next quarter. In 1993, the Company's
progress and the quality of Mr. Vincent's performance were reflected in
achievements in areas such as product development, facilities expansion and the
building of a solid management and financial structure.
 
     In determining whether or not to grant Mr. Vincent stock options as part of
his compensation package, the Stock and Option Plan Administration Committee
considers not only competitive factors and Mr. Vincent's performance but also
the number and terms of options previously granted. In recognition of his
performance and as an additional incentive for the future, Mr. Vincent was
granted a significant number of stock options in late 1992, with the
understanding that, barring unforeseen circumstances, no further options would
be granted to Mr. Vincent for the next three years.
 
IMPACT OF INTERNAL REVENUE CODE SECTION 162(M)
 
     Internal Revenue Code Section 162(m), enacted in 1993, precludes a public
corporation from taking a deduction in 1994 or subsequent years for compensation
in excess of $1 million paid to its chief executive officer or any of its four
other highest paid officers. At such time as this provision would impact the
Company, the Committees will assess the practical effect on executive
compensation and determine what action, if any, is appropriate.
 
                                       15
<PAGE>   20
 
COMMITTEES ROLES
 
     The stock option plans for senior executives are administered by the Stock
and Option Plan Administration Committee (Messrs. Morley and Stevens) of the
Board of Directors. Other compensation decisions for senior executives are made
by the Compensation and Management Resources Committee or, in the case of the
Chief Executive Officer, by the Board based on recommendations from that
Committee.
 
                                          James W. Stevens, Chairman,
                                          Compensation and
                                            Management Resources Committee
                                          Roger H. Morley
                                          Phillip A. Sharp
                                          James L. Vincent
 
                                       16
<PAGE>   21
<TABLE>
                               PERFORMANCE GRAPH
 
     The following graph compares the yearly percentage change in the Company's
cumulative total shareholder return on its Common Stock during a period
commencing on December 31, 1988 and ending December 31, 1993 (as measured by
dividing (i) the sum of (A) the cumulative amount of dividends for the
measurement period, assuming dividend reinvestment, and (B) the difference
between the Company's share price at the end and the beginning of the period; by
(ii) the share price at the beginning of the period) with the cumulative return
of the Standard & Poor's 500 Stock Index and the NASDAQ Pharmaceutical Stocks
Total Return Index. The NASDAQ Pharmaceutical Stocks Total Return Index, which
is calculated and supplied by NASDAQ, represents all companies trading on NASDAQ
under the Standard Industrial Classification (SIC) Code for pharmaceutical
companies which includes biotechnology companies. It should be noted that Biogen
has not paid dividends on its Common Stock, and no dividends are included in the
representation of the Company's performance. The stock price performance on the
graph below is not necessarily indicative of future price performance.
 
<CAPTION>                                                           NASDAQ         
      Measurement Period                                         Pharmaceutical 
    (Fiscal Year Covered)           BIOGEN          S&P 500         Index
<S>                                  <C>             <C>             <C>             
1988                                 100             100             100
1989                                 235             132             126
1990                                 407             128             151
1991                                 561             166             401
1992                                 660             179             334
1993                                 560             197             301
</TABLE>                             
 
                                       17
<PAGE>   22
 
                              CERTAIN TRANSACTIONS
 
     In connection with the hiring of certain executives, the Company has
granted bonuses contingent upon the executive's continued employment over a
period of years. In addition, the Company has also, in the ordinary course of
its business, made loans to certain executive officers and other key employees
in connection with their hiring to facilitate their relocation to the area.
 
                        RATIFICATION OF THE SELECTION OF
                            INDEPENDENT ACCOUNTANTS
 
     The Board of Directors has selected Price Waterhouse, independent
accountants, to examine the financial statements of the Company for the year
ending December 31, 1994. Price Waterhouse examined the Company's financial
statements for the year ended December 31, 1993. If the stockholders do not
ratify the selection of Price Waterhouse as the Company's independent
accountants, the Board of Directors will reconsider its selection. The Company
expects that representatives of Price Waterhouse will be present at the Meeting,
with the opportunity to make a statement if they so desire, and will be
available to respond to appropriate questions.
 
     THE BOARD OF DIRECTORS RECOMMENDS RATIFICATION OF THE SELECTION OF PRICE
WATERHOUSE AS THE COMPANY'S INDEPENDENT ACCOUNTANTS FOR THE FISCAL YEAR ENDED
DECEMBER 31, 1994.
 
                                 OTHER MATTERS
 
     The Company's officers, directors and greater than ten percent stockholders
are required to file reports of ownership and change of ownership with the
Securities and Exchange Commission under the Securities Exchange Act of 1934.
Based solely on information provided to the Company by the individual directors
and officers, the Company believes that, during the fiscal year ended December
31, 1993, all filing requirements applicable to executive officers and directors
were complied with except for the late reporting of 100 shares owned by Irvin D.
Smith upon commencement of his employment.
 
     The Board of Directors knows of no other business which will be presented
to the Meeting. If any other business is properly brought before the Meeting, it
is intended that proxies in the enclosed form will be voted in respect thereof
in accordance with the judgment of the persons voting the proxies.
 
     To be considered for presentation at the Annual Meeting of Stockholders to
be held in 1995, stockholder proposals must be received, marked for the
attention of the "Vice President -- General Counsel," Biogen, Inc., 14 Cambridge
Center, Cambridge, Massachusetts 02142, not later than December 16, 1994.
 
     The cost of soliciting proxies, including expenses in connection with
preparing and mailing this Proxy Statement, will be borne by the Company. In
addition, the Company will reimburse brokerage firms and other persons
representing beneficial owners of Common Stock of the Company for their expenses
in forwarding proxy material to such beneficial owners. Solicitation of proxies
by mail may be supplemented by telephone, telegram, telex and personal
solicitation by the Directors, officers or employees of the Company. No
additional compensation will be paid for such solicitation. In addition, the
Company has hired D.F. King & Co., Inc. to act as its proxy solicitation agent
to assist in the solicitation of proxies for the Meeting. The Company estimates
that the fees payable to D.F. King for such services will be approximately
$5,000.
 
                                       18
<PAGE>   23
 
     Notwithstanding anything to the contrary set forth in any of the Company's
previous filings under the securities laws that might incorporate future
filings, including this Proxy Statement, in whole or in part, the reports of the
compensation and stock option committees and the performance graph included in
this Proxy Statement shall not be incorporated by reference into any such
filings.
 
     WHETHER OR NOT YOU INTEND TO BE PRESENT AT THE MEETING, YOU ARE URGED TO
FILL OUT, SIGN, DATE AND RETURN THE ENCLOSED PROXY AT YOUR EARLIEST CONVENIENCE.
 
                                          By order of the Board of Directors:
 
                                          /s/ MICHAEL J. ASTRUE

                                          Michael J. Astrue
                                          Clerk
 
Cambridge, Massachusetts
April 18, 1994
 
                                       19
<PAGE>   24
 
                                [BIOGEN LOGO]
                             14 CAMBRIDGE CENTER
                             CAMBRIDGE, MA 02142



                                      
                           NOTICE OF ANNUAL MEETING
                             AND PROXY STATEMENT
                                      





                                 MEETING DATE
                                 JUNE 3, 1994
                                      






      YOUR VOTE IS IMPORTANT.
      PLEASE SIGN AND PROMPTLY RETURN
      YOUR PROXY IN THE ENCLOSED ENVELOPE.
<PAGE>   25
                                 BIOGEN, INC
          PROXY SOLICITED BY THE BOARD OF DIRECTORS OF BIOGEN, INC.
                    FOR THE ANNUAL MEETING OF STOCKHOLDERS
                          TO BE HELD ON JUNE 3, 1994

THE UNDERSIGNED HEREBY ACKNOWLEDGES RECEIPT OF THE NOTICE OF ANNUAL MEETING OF
STOCKHOLDERS AND PROXY STATEMENT, DATED APRIL 18, 1994, AND DOES HEREBY APPOINT
JAMES L. VINCENT AND MICHAEL J. ASTRUE, AND EACH OF THEM, PROXIES OF THE
UNDERSIGNED WITH ALL THE POWERS THE UNDERSIGNED WOULD POSSESS IF PERSONALLY
PRESENT AND WITH FULL POWER OF SUBSTITUTION IN EACH OF THEM, TO APPEAR AND VOTE
ALL SHARES OF COMMON STOCK OF BIOGEN, INC., A MASSACHUSETTS CORPORATION, WHICH
THE UNDERSIGNED WOULD BE ENTITLED TO VOTE IF PERSONALLY PRESENT AT THE ANNUAL
MEETING OF STOCKHOLDERS TO BE HELD AT THE ROYAL SONESTA HOTEL, 5 CAMBRIDGE
PARKWAY, CAMBRIDGE, MASSACHUSETTS ON FRIDAY, JUNE 3, 1994 AT 10:00 A.M. AND AT
ANY ADJOURNMENT THEREOF.

THE SHARES REPRESENTED HEREBY WILL BE VOTED AS DIRECTED HEREIN. IN EACH CASE IF
NO DIRECTION IS INDICATED, SUCH SHARES WILL BE VOTED FOR THE ELECTION OF THE
NAMED NOMINEES AS A DIRECTOR AND FOR PROPOSAL 2. AS TO ANY OTHER MATTER, SAID
PROXY HOLDERS WILL VOTE IN ACCORDANCE WITH THEIR BEST JUDGEMENT. THIS PROXY MAY
BE REVOKED IN WRITING AT ANY TIME PRIOR TO THE VOTING THEREOF.

IN THEIR DISCRECTION, THE PROXIES ARE ALSO AUTHORIZED TO VOTE UPON SUCH OTHER
MATTERS AS MAY PROPERLY COME BEFORE THE MEETING.

- --------------------------------------------------------------------------------
  PLEASE VOTE, DATE, AND SIGN ON OTHER SIDE AND RETURN PROMPTLY IN ENCLOSED
                                  ENVELOPE,
- --------------------------------------------------------------------------------
PLEASE SIGN THIS PROXY EXACTLY AS YOUR NAME APPEARS ON THE REVERSE SIDE. JOINT
OWNERS SHOULD EACH SIGN PERSONALLY. TRUSTEES AND OTHER FIDUCIARIES SHOULD
INDICATE THE CAPACITY IN WHICH THEY SIGN, AND WHERE MORE THAN ONE NAME APPEARS,
A MAJORITY MUST SIGN. IF A CORPORATION, THIS SIGNATURE SHOULD BE THAT OF AN
AUTHORIZED OFFICER WHO SHOULD STATE HIS OR HER TITLE.
- --------------------------------------------------------------------------------

HAS YOUR ADDRESS CHANGED?                      DO YOU HAVE ANY COMMENTS?

_________________________________              _________________________________

_________________________________              _________________________________

_________________________________              _________________________________


- --------------------------------------------------------------------------------

<TABLE>
<S>                                             <C>
/ X / PLEASE MARK VOTES 
      AS IN THIS EXAMPLE                                                                        With-   For All
                                                                                        For     hold    Except
                                                1.) Election of Directors.              /  /    /  /    /  /
                
              BIOGEN, INC.                          NOMINEES: Alexander Bearn, Harold W. Buirkle, and James L. Vincent for
                                                    a three year term ending at the Annual Meeting of Stockholders in 1997
                                                    and Phillip A. Sharp for a two year term ending at the Annual Meeting of
                                                    Stockholders in 1996.

                                                          ALEXANDER BEARN, HAROLD W. BUIRKLE, JAMES L. VINCENT
                                                                         AND PHILLIP A. SHARP

          RECORD DATE SHARES:                       If you do not wish your shares voted "FOR" a particular nominee, mark
                                                    the "For All Except" box and strike a line through the nominee's name.
                                                    Your shares will be voted for the remaining nominees.

                                                                                                       With-    For All
                                                                                               For     hold     Except
                                                2.) To ratify the selection by the Company's  /  /     /  /     /  /
                                                    Board of Directors of Price Waterhouse 
                                                    as the Company's independent accountants
                                                    for the fiscal year ending December 31,
                                                    1994.

                                                                Mark box at right if you plan to attend the meeting.            /  /
                                               ------------
Please be sure to sign and date this Proxy.    Date             Mark box at right if comments or address change have            /  /
- -----------------------------------------------------------     been noted on the reverse side of the card.


- ----Stockholder sign here------------Co-owner sign here----                                                             

</TABLE>

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