BIOGEN INC
PRE 14A, 1996-04-04
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1
 
                            SCHEDULE 14A INFORMATION
 
PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES EXCHANGE ACT OF 1934
 
FILED BY THE REGISTRANT /X/       FILED BY A PARTY OTHER THAN THE REGISTRANT / /
 
- --------------------------------------------------------------------------------
 
Check the appropriate box:
/X/ Preliminary Proxy Statement
/ / Definitive Proxy Statement
/ / Definitive Additional Materials
/ / Soliciting Material Pursuant to sec.240.14a-11(c) or sec.240.14a-12
 
                                  Biogen, Inc.
                (Name of Registrant as Specified In Its Charter)
                   (Name of Person(s) Filing Proxy Statement)
 
PAYMENT OF FILING FEE (CHECK THE APPROPRIATE BOX):
/X/ $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1), or 14a-6(j)(2).
/ / $500 per each party to the controversy pursuant to Exchange Act Rule
    14a-6(i)(3).
/ / Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.
 
    1) Title of each class of securities to which transaction applies:
 
    2) Aggregate number of securities to which transaction applies:
 
    3) Per unit price or other underlying value of transaction computed pursuant
       to Exchange Act
       Rule 0-11:
 
    4) Proposed maximum aggregate value of transaction:
 
    Set forth the amount on which the filing fee is calculated and state how it
    was determined.
 
/ / Check box if any part of the fee is offset as provided by Exchange Act Rule
    0-11(a)(2) and identify the filing for which the offsetting fee was paid
    previously. Identify the previous filing by registration statement number,
    or the Form or Schedule and the date of its filing.
 
    1) Amount Previously Paid:
 
    2) Form, Schedule or Registration Statement No.:
 
    3) Filing Party:
 
    4) Date Filed:
 
- --------------------------------------------------------------------------------
<PAGE>   2
                                                               Preliminary Proxy
 
[LOGO]
 
Notice of 1996 Annual Meeting
and Proxy Statement

[ARTWORK]

<PAGE>   3
                                                               Preliminary Proxy
 
- --------------------------------------------------------------------------------
 
[LOGO]
 
                                                                  April 12, 1996
 
Dear Stockholder:
 
     You are cordially invited to attend the 1996 Annual Meeting of Stockholders
of Biogen, Inc. to be held at 10:00 a.m. on Friday, May 31, 1996 at the
Company's offices located at 12 Cambridge Center, Cambridge, Massachusetts.
 
     At the Annual Meeting, three persons will be elected to the Board of
Directors. The Board of Directors recommends the re-election of the nominees
named in the Proxy Statement. In addition, the Company will ask the stockholders
to ratify the selection of Price Waterhouse LLP as the Company's independent
accountants for fiscal year ending December 31, 1996, and to approve an
amendment to the Company's Articles of Organization to increase the authorized
shares of Common Stock.
 
     Whether you plan to attend the Annual Meeting or not, it is important that
you promptly fill out, sign, date and return the enclosed proxy card in
accordance with the instructions set forth on the card. This will ensure your
proper representation at the Annual Meeting.
 
                                            Sincerely,
 
                                            LOGO
 
                                            James L. Vincent
                                            Chairman and Chief Executive Officer
 
     YOUR VOTE IS IMPORTANT. PLEASE REMEMBER TO RETURN YOUR PROXY PROMPTLY.
<PAGE>   4
                                                              Preliminary Proxy 

                                  BIOGEN, INC.
 
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                            TO BE HELD MAY 31, 1996
 
TO THE STOCKHOLDERS OF BIOGEN, INC.:
 
     NOTICE IS HEREBY GIVEN that the Annual Meeting of Stockholders of Biogen,
Inc., a Massachusetts corporation, will be held at 10:00 a.m. on Friday, May 31,
1996, at Biogen's offices located at 12 Cambridge Center, Cambridge,
Massachusetts 02142, for the following purposes:
 
          1. To elect three members to the Board of Directors to serve for a
     three-year term ending at the Annual Meeting of Stockholders in 1999 and
     until their successors are duly elected and qualified or their earlier
     resignation or removal.
 
          2. To ratify the selection of Price Waterhouse LLP as the Company's
     independent accountants for the fiscal year ending December 31, 1996.
 
          3. To approve an amendment to the Company's Articles of Organization
     to increase the number of authorized shares of Common Stock from 55,000,000
     shares to 110,000,000 shares.
 
          4. To transact such other business as may be properly brought before
     the Meeting and any adjournments thereof.
 
     The Board of Directors has fixed the close of business on April 8, 1996 as
the record date for the determination of stockholders entitled to notice of and
to vote at the Meeting and at any adjournments thereof.
 
     All stockholders are cordially invited to attend the Meeting. However, to
ensure your representation you are requested to complete, sign, date and return
the enclosed proxy as soon as possible in accordance with the instructions on
the proxy card. A return self-addressed envelope is enclosed for your
convenience.
 
                                            BY ORDER OF THE BOARD OF DIRECTORS
 
                                            [LOGO]
 
                                            JAMES L. VINCENT
                                            Chairman of the Board
 
Cambridge, Massachusetts
April 12, 1996
<PAGE>   5
                                                              Preliminary Proxy 
 
                                  BIOGEN, INC.
                              14 CAMBRIDGE CENTER
                         CAMBRIDGE, MASSACHUSETTS 02142
                                 (617) 679-2000
 
               PROXY STATEMENT FOR ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD ON MAY 31, 1996
 
     This Proxy Statement is furnished in connection with the solicitation by
the Board of Directors of Biogen, Inc. (the "Company") of proxies to be voted at
the Annual Meeting of Stockholders (the "Meeting") which will be held at the
Company's offices at 12 Cambridge Center, Cambridge, Massachusetts on Friday,
May 31, 1996 at 10:00 a.m., for the purposes stated in the accompanying Notice
of Annual Meeting of Stockholders. Shares represented by valid proxies, received
in time for the Meeting and not revoked prior to the Meeting, will be voted at
the Meeting. A stockholder may revoke a proxy before the proxy is voted by
delivering to the Secretary of the Company a signed statement of revocation or a
duly executed proxy bearing a later date. Any stockholder at the Meeting who has
executed a proxy but is present may vote in person by revoking the proxy. This
Proxy Statement and the accompanying proxy are being mailed on or about April
12, 1996 to all stockholders entitled to notice of and to vote at the Meeting.
 
     The close of business on April 8, 1996 is the record date for determining
the stockholders entitled to notice of and to vote at the Meeting. On that date,
the Company had           shares of Common Stock outstanding and entitled to
vote.
 
                             ELECTION OF DIRECTORS
 
     The Company's Board of Directors consists of nine members divided into
three equal classes serving staggered three-year terms. The term of one class of
Directors expires at the Meeting. Three Directors are to be elected to the class
whose term expires at the Meeting, to hold office until the Annual Meeting of
Stockholders in 1999 and until their successors are duly elected and qualified.
 
VOTE
 
     A plurality of the votes cast at the Meeting is required to elect a
Director. If any nominee is unable or unwilling to accept nomination or
election, the shares represented by the enclosed proxy will be voted for the
election of such other person as the Board of Directors may recommend. THE BOARD
OF DIRECTORS RECOMMENDS ELECTION OF MESSRS. MORLEY AND TOBIN AND DR. SHARP AS
DIRECTORS.
 
INFORMATION ABOUT THE DIRECTORS

[PHOTO]
Alexander G. Bearn, M.D.
(age 73)               Director since 1991; Member of the class of Directors
                       with term ending in 1997; Visiting Physician, Adjunct
                       Professor at the Rockefeller University in New York since
                       1966 and Trustee of the Rockefeller University since
                       1970; Trustee of Howard Hughes Medical Institute since
                       1987; from 1979 to 1988 Senior Vice President for Medical
                       and Scientific Affairs of the International Division of
                       Merck & Co.; Director of Vasomedical, Inc.; member of the
                       Scientific Board of the Company and nominated as a
                       Director pursuant to designation by the Scientific Board.



                                      1
<PAGE>   6
                                                              Preliminary Proxy 

 
                       Director since 1990; Member of the class of Directors
                       with term ending in 1998; President, Chief Operating
[PHOTO]                Officer and Director, Allied-Signal, Inc. from 1988 to
                       1993; from 1983 to 1988, Executive Vice President and
                       President, Engineered Materials Sector, Allied-Signal,
                       Inc.
Alan Belzer
(age 63)

                       Director since 1986; Member of class of Directors with
                       term ending in 1997; Managing Director, The Henley Group,
[PHOTO]                Inc. from 1986 to 1990; from 1983 to 1985, Executive Vice
                       President, Finance and Planning, Allied Corporation (now
                       Allied-Signal, Inc.)
Harold W. Buirkle
(age 75)
                       Director since 1987; Vice President, Schiller
                       International University, Heidelberg, Germany since 1983;
[PHOTO]                Director of Artal, S.A., Luxembourg; Director of Lorraine
                       Investments Luxembourg S.A.; Co-Managing Director, R&R
                       Inventions Ltd., Birmingham, U.K; Advisory Director of
                       Bank of America, Illinois.

Roger H. Morley
(age 64)
NOMINEE FOR RE-ELECTION


                       Director since 1980; Member of the class of Directors
                       with term ending in 1998; Biogen Professor of Molecular
[PHOTO]                Biology, University of Edinburgh, Scotland since 1984;
                       during 1985 and 1986, Interim Research Director of Biogen
                       S.A; Fellow of the Royal Society; Vice Chairman of the
                       Scientific Board of the Company and nominated as a
                       Director pursuant to designation by the Scientific Board.

Sir Kenneth Murray, Ph.D.
(age 65)

                                      2
<PAGE>   7
                                                              Preliminary Proxy 

 
                       Director since 1982; Salvador E. Luria Professor and Head
                       of the Department of Biology, Center for Cancer Research,
                       Massachusetts Institute of Technology since 1991;
[PHOTO]                Director of the Center for Cancer Research at MIT from
                       1985 to 1991; Chairman of the Scientific Board of the
                       Company and nominated as a Director pursuant to
                       designation by the Scientific Board; Nobel Laureate.
Phillip A. Sharp, Ph.D.
(age 51)
NOMINEE FOR RE-ELECTION

                       Director since 1986; Member of the class of Directors
                       with term ending in 1998; Chairman, Prudential Asset
                       Management Group from 1993 to January 1995; Executive
                       Vice President, The Prudential Insurance Company of
[PHOTO]                America and Prudential Investment Corporation from 1987
                       to January 1995; Managing Director, Dillon, Read &
                       Company Inc. from 1985 until 1987; from 1984 until 1985,
                       Group Executive of Citicorp and Citibank N.A. and
                       Chairman of Citicorp Venture Capital, Ltd; Director of
                       Prudential Equity Investors, Inc.
James W. Stevens
(age 59)

                       Director since 1994; President and Chief Operating
                       Officer of Biogen, Inc. since February 1994; from 1992 to
[PHOTO]                1993, President and Chief Operating Officer of Baxter
                       International; from 1988 to 1992, Executive Vice
                       President of Baxter International; Director of Creative
                       BioMolecules, Inc., Medisense, Inc., and Genovo, Inc.
James R. Tobin
(age 51)
NOMINEE FOR RE-ELECTION

                       Director since 1985; Member of class of Directors with
                       term ending in 1997; Chief Executive Officer and Chairman
                       of the Board of Directors of Biogen, Inc. since 1985 and
[PHOTO]                President from 1985 to February 1994; from 1982 to 1985,
                       Group Vice President, Allied Corporation (now
                       Allied-Signal, Inc.) and President, Allied Health and
                       Scientific Products Company; from 1979 through 1980,
                       Executive Vice President, Chief Operating Officer and a
                       Director of Abbott Laboratories, Inc.
James L. Vincent
(age 56)


INFORMATION REGARDING THE BOARD AND ITS COMMITTEES
 
     The Board has a Compensation and Management Resources Committee, a Finance
and Audit Committee, a Stock and Option Plan Administration Committee, a
Nominating Committee and a Project Share Committee. The Compensation and
Management Resources Committee, whose members in 1995 were

                                      3
<PAGE>   8
                                                              Preliminary Proxy 
 
James W. Stevens (Chairman), Roger H. Morley, Phillip A. Sharp and James L.
Vincent, makes recommendations to the Board concerning remuneration and benefits
for senior executives, and reviews executive development and succession. The
Finance and Audit Committee, whose members in 1995 were Harold W. Buirkle
(Chairman), Alan Belzer, Roger H. Morley and James R. Tobin, reviews the
Company's quarterly and annual financial statements and Annual Report on Form
10-K, considers matters relating to accounting policy and internal controls,
reviews the scope of annual audits, recommends independent public accountants to
the Board and makes recommendations concerning financial, investment and
taxation policies. The Project Share Committee, whose members in 1995 were
Phillip A. Sharp (Chairman), Kenneth Murray and James L. Vincent, recommends to
the Board stock and stock option awards for scientific consultants. The Stock
and Option Plan Administration Committee, whose members in 1995 were Roger H.
Morley and James W. Stevens, administers certain stock and stock option plans.
In December 1995 the Board of Directors formed a nominating committee to
identify, evaluate and nominate candidates to fill Board positions. The members
of the Nominating Committee are Alan Belzer (Chairman), Kenneth Murray,
Alexander G. Bearn, James W. Stevens and James L. Vincent. The Nominating
Committee will consider nominees recommended by the Company's stockholders.
Stockholders wishing to nominate a person for election to the Board of Directors
must follow the procedures described in the Company's by-laws.
 
     The Board of Directors and each of the Committees, except for the Project
Share Committee and the Nominating Committee, met five times in 1995. The
Project Share Committee and the Nominating Committee did not meet in 1995. No
Director attended fewer than 75% of the total number of meetings of the Board
and of Committees of the Board on which he served during 1995.
 
     Non-employee members of the Company's Board of Directors receive a $20,000
per year retainer, $1,500 for each Board meeting attended and $500 for attending
each meeting of Committees of the Board on which they serve, except for
Committee chairmen, who receive $1,000 per Committee meeting attended. Those
Directors who are members of the Company's Scientific Board and who are not
Company employees also receive an annual consulting fee of $15,000, $1,500 per
day for Scientific Board meetings, and $500 per day for each full working day
spent in the Company's laboratories, except for the Chairman of the Scientific
Board whose annual consulting fee in 1995 was $60,000. Directors who are not
members of the Company's Scientific Board are eligible to participate in the
Company's 1985 Non-Qualified Stock Option Plan (the "1985 Plan"). Directors who
are members of the Scientific Board are eligible to participate in the Company's
1987 Scientific Board Stock Option Plan. Directors may defer all or part of
their cash compensation pursuant to the Company's Voluntary Board of Directors
Savings Plan.
 
                        RATIFICATION OF THE SELECTION OF
                            INDEPENDENT ACCOUNTANTS
 
     The Board of Directors has selected Price Waterhouse LLP, independent
accountants, to examine the financial statements of the Company for the year
ending December 31, 1996. Price Waterhouse examined the Company's financial
statements for the year ended December 31, 1995. If the stockholders do not
ratify the selection of Price Waterhouse as the Company's independent
accountants, the Board of Directors will reconsider its selection. The Company
expects that representatives of Price Waterhouse will attend the Meeting, with
the opportunity to make a statement if they so desire, and will be available to
respond to appropriate questions.
 
     THE BOARD OF DIRECTORS RECOMMENDS RATIFICATION OF THE SELECTION OF PRICE
WATERHOUSE LLP AS THE COMPANY'S INDEPENDENT ACCOUNTANTS FOR THE FISCAL YEAR
ENDING DECEMBER 31, 1996.
 
                                        4
<PAGE>   9
                                                              Preliminary Proxy 
 
                                SHARE OWNERSHIP

<TABLE>
 
     The following table sets forth information as of April 3, 1996 concerning
the ownership of Common Stock by each stockholder known by the Company to be the
beneficial owner of more than 5% of the Company's outstanding shares of Common
Stock, each current member of the Board of Directors, each of the executive
officers named in the Summary Compensation Table included in this Proxy
Statement and all current Directors and executive officers as a group. Except as
otherwise noted, the persons or entities identified have sole voting and
investment power with respect to their shares.
 
<CAPTION>
                                                                          SHARES BENEFICIALLY
                                                                                 OWNED
                                                                        ------------------------
NAME AND ADDRESS**                                                      NUMBER(1)     PERCENT(1)
- ------------------                                                      ---------     ----------
<S>                                                                     <C>                 <C>
Alexander G. Bearn....................................................     28,100(2)        *
Alan Belzer...........................................................     35,000(3)        *
Harold W. Buirkle.....................................................    105,000(4)        *
Roger H. Morley.......................................................     26,000(3)        *
Kenneth Murray........................................................    233,000(5)        *
Phillip A. Sharp......................................................    220,000(6)        *
James W. Stevens......................................................     71,000(7)        *
James R. Tobin........................................................    128,965(8)        *
James L. Vincent......................................................    918,088(9)         %
Joseph M. Davie.......................................................    107,509(10)       *
Kenneth M. Bate.......................................................    153,652(11)       *
Irvin D. Smith........................................................    110,545(12)       *
All executive officers and Directors as a group (18 persons)..........  2,594,899(13)        %
FMR Corp..............................................................  3,757,700(14)        %
  82 Devonshire Street
  Boston, MA 02109
Twentieth Century Companies...........................................  2,700,000(15)        %
  4500 Main Street
  P.O. Box 418210
  Kansas City, MO 64141
Jundt Associates, Inc.................................................  1,952,300(16)        %
  1550 Utica Avenue South
  Suite 950
  Minneapolis, MN 55416

<FN> 
- ---------------
  *  Represents beneficial ownership of less than 1% of the Company's
     outstanding shares of Common Stock.
 
 **  Addresses are given for beneficial owners of more than 5% of the
     outstanding Common Stock only.
 
 (1) All references to options in these notes mean those options which are held
     by the respective person on April 3, 1996 and which are exercisable on
     April 3, 1996 or become exercisable on or before sixty days after April 3,
     1996. The calculation of percentages is based upon the number of shares
     issued and outstanding at April 3, 1996, plus shares subject to options
     held by the respective person at April 3, 1996, which are exercisable on
     April 3, 1996 or become exercisable on or before sixty days after April 3,
     1996.
 
 (2) Includes 28,000 shares which may be acquired pursuant to options.

</TABLE>
 
                                        5
<PAGE>   10
                                                              Preliminary Proxy 
 
 (3) Represents shares which may be acquired pursuant to options.
 
 (4) Includes 31,000 shares which may be acquired pursuant to options.
 
 (5) Includes 42,000 shares which may be acquired pursuant to options.
 
 (6) Includes 42,000 shares which may be acquired pursuant to options.
 
 (7) Includes 61,000 shares which may be acquired pursuant to options.
 
 (8) Includes 118,285 shares which may be acquired pursuant to options, 125
     shares acquired as matching contributions under the Company's 401(k) plan
     and 200 shares held by Mr. Tobin's children.
 
 (9) Includes 720,000 shares which may be acquired pursuant to options. Certain
     of the shares acquired upon exercise of such options are subject to
     repurchase by the Company under certain circumstances. Includes 1,088
     shares acquired as matching contributions under the Company's 401(k) plan.
     Includes 3,500 shares held by Mr. Vincent's wife.
 
(10) Includes 107,142 shares which may be acquired pursuant to options and 39
     shares acquired as matching contributions under the Company's 401(k) plan.
 
(11) Includes 153,333 shares which may be acquired pursuant to options and 319
     shares acquired as matching contributions under the Company's 401(k) plan.
 
(12) Includes 110,000 shares which may be acquired pursuant to options and 141
     shares acquired as matching contributions under the Company's 401(k) plan.
 
(13) Includes 1,927,592 shares which may be acquired pursuant to options. Does
     not include shares which may be purchased in 1996 by executive officers who
     are currently participants in the 1983 Employee Stock Purchase Plan.
     Includes 3,980 shares acquired as matching contributions under the
     Company's 401(k) plan.
 
(14) FMR Corp. ("FMR") is a parent holding company. Fidelity Management &
     Research Company ("Fidelity"), a wholly-owned subsidiary of FMR Corp., is
     the beneficial owner of 3,451,400 shares as a result of acting as an
     investment adviser to various investment companies. Fidelity Management
     Trust Company ("FMTC"), a wholly-owned subsidiary of FMR, is the beneficial
     owner of 276,500 shares as a result of its serving as an investment manager
     of institutional accounts. Also included are 29,800 shares held by Fidelity
     International Limited, of which FMR disclaims beneficial ownership. FMR and
     Edward C. Johnson 3d, through their control of Fidelity and FMTC, have sole
     power to dispose of the shares beneficially owned by Fidelity and FMTC and
     sole power to vote 103,500 of the shares beneficially owned by FMTC. The
     above information was reported on Schedule 13G as of December 31, 1995.
 
(15) Twentieth Century Investors, Inc. ("TCI"), the owner of the shares, is an
     investment company managed by Investors Research Corporation ("IRC"), a
     registered investment advisor. As a result of its status as investment
     adviser, IRC may be deemed to be the beneficial owner of the 2,700,000
     shares held by TCI. IRC is a wholly-owned subsidiary of Twentieth Century
     Companies, Inc. ("TCC") which is controlled by James E. Stowers, Jr. Both
     TCC and Mr. Stowers may also be deemed to be beneficial owners of the
     shares held by TCI. TCC, IRC and Mr. Stowers each disclaims beneficial
     ownership of the shares held by TCI. The above information was reported on
     Schedule 13G as of December 31, 1995.
 
(16) Jundt Associates, Inc. ("Jundt") manages accounts for the benefit of its
     clients. Jundt exercises sole dispositive power over all of the shares.
     Jundt has sole voting power over 1,335,700 of the shares. The above
     information was reported on a Schedule 13G as of February 8, 1996.
 
                                        6
<PAGE>   11
                                                              Preliminary Proxy 
 
                             EXECUTIVE COMPENSATION
<TABLE>
     The following table sets forth the compensation of the Company's Chief
Executive Officer and the four other most highly compensated executive officers
(the "Named Executive Officers") during the three fiscal years ended December
31, 1995.
 
SUMMARY COMPENSATION TABLE
<CAPTION>
                                                                             LONG-TERM
                                                                            COMPENSATION
                                        ANNUAL COMPENSATION                 ------------
                           ----------------------------------------------      SHARES
   NAME AND PRINCIPAL                                      OTHER ANNUAL      UNDERLYING       ALL OTHER
        POSITION           YEAR    SALARY       BONUS     COMPENSATION(1)    OPTIONS(#)    COMPENSATION(2)
- -------------------------  ----   --------     --------   ---------------   ------------   ---------------
<S>                        <C>    <C>          <C>           <C>               <C>             <C>
James L. Vincent.........  1995   $775,000     $365,000      $       0         300,000         $33,809
  Chairman and Chief       1994    700,000      350,000              0               0          25,431
  Executive Officer        1993    635,000      310,000              0               0          21,139

James R. Tobin...........  1995    430,000      245,000         94,690          40,000           4,123
  President and Chief      1994    338,470(3)   235,000        150,098         440,000           3,217
  Operating Officer        1993        N/A          N/A            N/A             N/A             N/A

Joseph M. Davie..........  1995    282,000       55,000         25,000               0           4,790
  Vice President --        1994    260,000       73,000         47,805               0           1,783
  Research                 1993    190,000(3)    75,000         99,987         250,000             892

Kenneth M. Bate..........  1995    262,000       60,000         20,000          18,000           3,335
  Vice President --        1994    242,000       63,000         20,000          25,000           3,335
  Marketing and Sales      1993    220,000       72,000         25,640          25,000           3,207

Irvin D. Smith...........  1995    241,000       69,000              0               0           2,310
  Vice President(4)        1994    225,000       61,000         81,323               0           2,310
                           1993    144,324(3)    70,000         98,241          25,000             909
<FN>
 
- ---------------
(1) Other Annual Compensation in 1995 for Mr. Tobin, Dr. Davie and Mr. Bate
    includes the portion of payments made under a contingent bonus and mortgage
    loan forgiveness program in connection with their hiring which became vested
    during the last fiscal year in the amount of $92,696, $25,000 and $20,000
    respectively. Other Annual Compensation for Mr. Tobin includes $1,109 in
    relocation expense payments and $885 in payments to cover taxes on
    relocation expense reimbursement.
 
(2) All Other Compensation for Mr. Vincent, Mr. Tobin, Dr. Davie, Mr. Bate and
    Dr. Smith includes the dollar value of matching contributions made in shares
    of the Company's Common Stock during the last fiscal year under the
    Company's 401(k) plan in the amount of $2,250, $2,250, $2,115, $2,250 and
    $2,250, respectively, and matching amounts of less than $100 per officer
    made by the Company under its non-qualified Voluntary Executive Supplemental
    Savings Plan for compensation in excess of the amount that may be taken into
    account under the 401(k) plan. All Other Compensation also includes, for
    each of the named individuals except Dr. Smith, the dollar value of premiums
    paid by the Company during the last fiscal year with respect to term life
    insurance for their benefit under an executive life insurance program in the
    amount of $31,499 for Mr. Vincent, $1,813 for Mr. Tobin, $2,675 for Dr.
    Davie and $1,025 for Mr. Bate.
 
(3) Includes compensation only for the period of the year during which the
    individual was employed by the Company.
 
(4) Dr. Smith was Vice President -- Development Operations during 1995.
</TABLE>
 
                                        7
<PAGE>   12
                                                              Preliminary Proxy 
 
OPTION GRANTS IN LAST FISCAL YEAR
 
     The following table sets forth information regarding options granted to the
Named Executive Officers in 1995.
 
<TABLE>
<CAPTION>
                                                                                                      POTENTIAL REALIZABLE
                                       INDIVIDUAL GRANTS                                                VALUE AT ASSUMED
- -----------------------------------------------------------------------------------------------          ANNUAL RATES OF
                                   NUMBER OF        % OF TOTAL                                             STOCK PRICE
                                     SHARES          OPTIONS                                            APPRECIATION FOR
                                   UNDERLYING        GRANTED                                             OPTION TERM(2)
                                    OPTIONS        TO EMPLOYEES       EXERCISE       EXPIRATION     -------------------------
NAME                               GRANTED(1)     IN FISCAL YEAR     PRICE($/SH)        DATE          5%($)          10%($)
- ----                               ----------     --------------     -----------     ----------     ----------     ----------
<S>                                  <C>               <C>            <C>             <C>           <C>            <C>
James L. Vincent.................    300,000           26.60          53.938          9/22/05       10,176,395     25,788,984
James R. Tobin...................     40,000            3.55          53.938          9/22/05       1,356,853      3,438,531
Joseph M. Davie..................          0            0               N/A             N/A            N/A            N/A
Kenneth M. Bate..................     18,000            1.60          53.938          9/22/05        610,584       1,547,339
Irvin D. Smith...................          0            0               N/A             N/A            N/A            N/A
 
<FN>
- ---------------
 
(1) All options listed were granted pursuant to the 1985 Plan at the market
    price on the date of grant and have a ten-year term. The options granted to
    Mr. Tobin and Mr. Bate vest annually in six installments commencing one year
    from the date of grant. The options granted to Mr. Vincent are immediately
    exercisable, but the shares are subject to repurchase by the Company under
    certain conditions and for a specified period.
 
(2) The potential realizable values for all stockholders at the assumed annual
    rates of stock price appreciation of 5% and 10% would be $1,370,455,803 and
    $3,473,004,079, respectively. These values assume increases in the value of
    the shares of Common Stock outstanding at December 29, 1995 at the stated
    percentages over a ten-year period from an initial value of $61.375, the
    average of the high and low sales prices of the Company's Common Stock on
    December 29, 1995.

</TABLE>
 
AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR AND YEAR-END OPTION VALUES
 

<TABLE>
     The following table sets forth information regarding options held by the
Named Executive Officers of the Company in 1995.
 
<CAPTION>
                                                                    NUMBER OF SHARES                VALUE OF UNEXERCISED
                                                                 UNDERLYING UNEXERCISED             IN-THE-MONEY OPTIONS
                                                                   OPTIONS AT YEAR-END                 AT YEAR-END(1)
                          SHARES ACQUIRED        VALUE        -----------------------------     -----------------------------
NAME                      ON EXERCISE(#)      REALIZED($)     EXERCISABLE     UNEXERCISABLE     EXERCISABLE     UNEXERCISABLE
- ----                      ---------------     -----------     -----------     -------------     -----------     -------------
<S>                           <C>             <C>               <C>              <C>            <C>               <C>
James L. Vincent........      299,000         11,250,120        720,000                0        $14,277,015(2)    $       0
James R. Tobin..........            0                  0         61,142          418,858            889,560       5,967,920
Joseph M. Davie.........            0                  0         71,428          178,572          2,455,357       6,138,393
Kenneth M. Bate.........       25,000            785,937        153,333           74,667          5,295,000       1,429,491
Irvin D. Smith..........       10,000            288,750        110,000                0          3,817,500               0
 
<FN>
- ---------------
 
(1) The value of unexercised in-the-money options at year-end assumes a fair
    market value for the Company's Common Stock of $61.375, the average of the
    high and low sales prices of the Company's Common Stock on December 29,
    1995.
 
(2) Options granted to Mr. Vincent vest immediately, but the shares issuable
    upon exercise of the options are subject to repurchase by the Company under
    certain conditions and for a specified period.

</TABLE>
 
                                        8
<PAGE>   13
                                                              Preliminary Proxy 
 
PENSION PLAN
 
     The Company has a defined benefit pension plan in which all permanent U.S.
employees participate as of the first day of the quarter following date of hire.
Effective April 1, 1996, the pension formula changed to an account balance
approach. At the end of each plan year, a basic credit ranging from 2% to 15% of
compensation, based on participant's age and pay, is added to a participant's
account balance. In addition, a participant may receive a supplemental credit
equal to 3% (or the basic credit, if less) times compensation during the year
over the participant's Social Security covered compensation level. Account
balances grow each year at a specified rate of interest equal to the average of
the One-Year Treasury Bill (T-bill) rate for the prior year plus 1%. The plan's
interest credit will never be less than 5.25% nor more than 10%. The total
account balance is converted to a monthly pension at retirement. Alternatively,
a participant may elect to receive his or her account balance as a lump sum as
early as age 55. For 1995 and earlier years, the benefit formula provided at
different times varying amounts of benefit accrual. Each person who was a
participant on or before October 31, 1986 (the date at which the plan changed
from a defined contribution to a defined benefit plan) will receive a pension of
not less than the value of his or her account balance as of such date, plus
interest at the rate of 8%. A participant's interest in the plan is subject to a
graded vesting schedule based on years of service with Biogen and fully vests
after seven years of service.
 
     The Company also maintains the Biogen Supplemental Executive Retirement
Plan ("SERP"). For certain executive officers, the SERP benefit formula provides
for each year of participation 1.5% of compensation during the year up to the
Social Security taxable wage base for such year and 2.5% of compensation above
the wage base. This benefit formula preserves for SERP participants the level of
retirement benefits provided under the pension plan's benefit formula before its
amendment effective in 1989 to comply with the Tax Reform Act of 1986. The SERP
also provides benefits that, due to tax law limits, cannot be paid from the
pension plan.
 
<TABLE>
     The following table shows estimated annual benefits payable upon retirement
(age 65) for life under the pension plan and the SERP. These estimates assume
that an employee will work for the Company until normal retirement age with no
change from 1995 compensation and that the Social Security taxable wage base in
1996 of $62,700 will not change.
 
<CAPTION>
CURRENT SALARY
PLUS BONUS                            15           20           25            30             35
- ----------                         --------     --------     --------     ----------     ----------
<S>                                <C>          <C>          <C>          <C>            <C>
$ 200,000........................  $ 66,000     $ 88,000     $110,000     $  132,000     $  154,000
   300,000.......................   103,000      137,000      171,000        206,000        240,000
   400,000.......................   140,000      186,000      233,000        280,000        326,000
   500,000.......................   178,000      237,000      296,000        356,000        415,000
   600,000.......................   215,000      286,000      358,000        430,000        501,000
   700,000.......................   253,000      337,000      421,000        506,000        590,000
   800,000.......................   290,000      386,000      483,000        580,000        676,000
   900,000.......................   328,000      437,000      546,000        656,000        765,000
 1,000,000.......................   365,000      486,000      608,000        730,000        851,000
 1,100,000.......................   403,000      537,000      671,000        806,000        940,000
 1,200,000.......................   440,000      586,000      733,000        880,000      1,026,000
 1,300,000.......................   478,000      637,000      796,000        956,000      1,115,000
 1,400,000.......................   515,000      686,000      858,000      1,030,000      1,201,000
</TABLE>
                                                                           
                                        9                                  
<PAGE>   14
                                                              Preliminary Proxy 
 
     The (i) current pensionable earnings (salary and bonus), (ii) current years
of service, and (iii) projected total service at age 65 are as follows for each
of the executive officers named in the compensation and option tables: Mr.
Vincent ($1,140,000, 10.5 years, 19 years (projected)); Mr. Tobin ($675,000, 2.0
years, 16.0 years (projected)); Dr. Davie ($337,000, 3.0 years, 11.5 years
(projected)); Mr. Bate $322,000, 5.5 years, 26 years (projected)); and Dr. Smith
($310,000, 4.5 years, 5.5 years (projected)).
 
EMPLOYMENT ARRANGEMENTS WITH THE COMPANY AND CERTAIN TRANSACTIONS
 
     Mr. Tobin, Dr. Davie, Mr. Bate and Dr. Smith have employment agreements
with the Company under which they receive executive life insurance and tax
preparation services. Dr. Davie's, Mr. Bate's and Dr. Smith's employment
agreements each further provides for compensation in the event of termination by
the Company, other than for cause, in the amount of base salary and certain
medical benefits, for twelve months or until alternative employment is obtained,
if earlier. Mr. Tobin's agreement provides for payment of $2.5 million, reduced
by any profit from his exercise of vested stock options, in the event his
employment terminates under certain circumstances. Mr. Vincent has an agreement
under which he receives term life, disability, and personal liability insurance,
personal income tax return preparation and tax audit services. Mr. Vincent's
agreement also provides for a minimum bonus of 25% of base salary if his
performance is satisfactory. In addition, Mr. Vincent will be entitled to
receive the discounted present value of an amount equal to compensation for 30
months following non-cause termination (whether by the Company, or in certain
cases, by Mr. Vincent) based on his last annual salary and bonus, together with
the amount of certain excise taxes imposed on such termination payments.
 
     In connection with the hiring of certain executives, the Company has
granted bonuses contingent upon the executive's continued employment over a
period of years. The Company has also, in the ordinary course of its business,
made loans to certain executive officers and other key employees in connection
with their hiring to facilitate their relocation to the area.
 
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
 
     In 1995, the members of the Compensation and Management Resources
Committee, which determines cash remuneration and benefits for senior executives
and reviews executive development and succession, were James W. Stevens
(Chairman), Roger H. Morley, Phillip A. Sharp and James L. Vincent, the Chairman
of the Board and Chief Executive Officer of the Company.
 
                    JOINT REPORT ON COMPENSATION PHILOSOPHY
                       BY THE COMPENSATION AND MANAGEMENT
                       RESOURCES COMMITTEE AND STOCK AND
                      OPTION PLAN ADMINISTRATION COMMITTEE
 
     The success of Biogen's mission, to move from a development-stage company
to a fully-integrated pharmaceutical company, will depend heavily on its ability
to recruit, motivate and retain senior executives with demonstrated talent and
managerial leadership skills typically gained from successful experiences in
positions of greater scope and responsibility in pharmaceutical and other
industry settings. A competitive compensation program is a crucial part of the
Company's effort to fulfill its mission. The Biogen executive compensation
program consists of three parts: base salary and benefits, annual bonus and
stock options. The Company's target for total compensation is to be competitive
with Fortune 500 pharmaceutical companies, which typically results in Biogen pay
levels at or above the 75th percentile of the biotechnology industry. In
 
                                       10
<PAGE>   15
                                                              Preliminary Proxy 
 
1995, the total compensation package paid to executive officers, other than the
Chief Executive Officer, was slightly above average compared to the major
biotechnology companies with respect to cash compensation, and above average
with respect to the value of stock options granted. Individual compensation
decisions are made with reference to progress toward goals tailored for Biogen's
stage of development, rather than traditional measures of a company's
performance, such as short-term earnings per share, which often do not relate to
the successful execution of the strategy which Biogen is pursuing.
 
BASE SALARY AND BENEFITS
 
     Company philosophy is to maintain executive base salary at a competitive
level sufficient to recruit individuals possessing the skills and values
necessary to achieve the Company's vision and mission over the long term.
Determinations of appropriate base salary levels and other compensation elements
are generally made through participation in a variety of industry surveys and
studies, as well as by monitoring developments in key industries such as the
pharmaceutical industry. Periodic adjustments in base salary relate to
competitive factors and to individual performance evaluated against
pre-established objectives. Executive officers are also entitled to participate
in benefit plans generally available to employees and receive executive life
insurance and other benefits as described elsewhere in this Proxy Statement.
 
ANNUAL BONUS
 
     The Compensation and Management Resources Committee of the Board, in its
discretion, may award bonuses to executive officers, and the Company pays
bonuses based on each executive officer's performance goals. The intent of the
annual bonus is to motivate and reward performance of senior executives measured
against distinct and clearly articulated goals in light of the competitive
compensation practices of the biotechnology industry. The goals vary with
responsibilities and are based on individual milestones rather than overall
measures of the Company's performance. In 1995, these goals included achievement
of certain clinical milestones with respect to early stage product candidates,
completion of certain key regulatory filings relating to AVONEX(TM) interferon
beta-1a ("AVONEX(TM)"), a positive recommendation of the Advisory Committee of
the FDA with respect to AVONEX(TM), accomplishment of key steps in the building
of a sales and marketing organization to sell AVONEX(TM), completion of key
systems necessary to support sales of AVONEX(TM), acquisition of new
technologies (gene therapy), completion of certain milestones related to
manufacturing capacity, and progress on certain other steps necessary for the
Company to achieve its goal of becoming a fully-integrated pharmaceutical
company.
 
STOCK OPTIONS
 
     Stock options are a fundamental element in the total compensation program
because they emphasize long-term Company performance as measured by creation of
stockholder value and foster a community of interest between stockholders and
employees. Accordingly, the Company believes that the use of stock options is
preferable to other forms of stock compensation such as restricted stock.
Options are granted to all permanent full-time employees, and particularly to
key employees likely to contribute significantly to the Company. In determining
the size of an option grant to an executive officer, the Company considers not
only competitive factors, changes in responsibility and the executive officer's
achievement of individual pre-established goals, but also the number and terms
of options previously granted to the officer. In addition, the Company usually
makes a significant grant of options when an executive officer joins the
Company. The size of option grants to executive officers is determined by the
Stock and Option Plan Administration Committee.
 
                                       11
<PAGE>   16
                                                              Preliminary Proxy 
 
     Options are granted, as a matter of Company policy, at 100% of the fair
market value on the date of grant. The Company generally awards options to
officers on employment and at regular intervals, but other awards may be made.
Some of the Company's stock option plans also provide for granting options to
members of the Board of Directors and the Scientific Board. Options granted to
employees generally vest over periods ranging from six to seven years after
grant.
 
CEO COMPENSATION
 
     The compensation of Biogen's Chief Executive Officer reflects the Company's
philosophy. Mr. Vincent has extensive pharmaceutical industry experience and was
hired in 1985 from one of the nation's largest corporations at a time when
Biogen's financial condition and prospects were considerably weaker than today.
The terms of his employment, which included his initial stock option grants,
were structured to provide significant incentives to contribute to the Company's
success. Under those terms, he receives a base salary that increases based on
inflation and his performance, and an annual bonus computed as a percentage of
base salary based on a minimum bonus of 25% of base salary when his performance
is satisfactory, with a significantly higher bonus when his performance is more
than satisfactory.
 
     Mr. Vincent's compensation is not formula-based but rather is determined by
the Board based upon the recommendation of the Compensation and Management
Resources Committee and the Stock and Option Plan Administration Committee based
on the Committees' assessment of Mr. Vincent's performance and review of data
showing the compensation of Mr. Vincent's peers in the pharmaceutical industry.
Mr. Vincent's performance is evaluated by the Committees by considering various
factors, including the breadth of Mr. Vincent's responsibilities and progress
made by the Company toward becoming a fully-integrated pharmaceutical company as
measured by the Committees' assessment of the performance of the key
departments. In 1995, the Company's progress and the quality of Mr. Vincent's
performance were reflected in the positive recommendation of the Advisory
Committee of the FDA with respect to AVONEX(TM), the quality and efficiency of
the Company's preparation for anticipated launch of AVONEX(TM) and achievements
in other areas such as facilities expansion, financial management and new
technology access (gene therapy).
 
     In determining whether to grant Mr. Vincent options, the Board and the
Committees consider not only competitive factors and Mr. Vincent's performance
but also the number and terms of options previously granted. In recognition of
his performance in light of the factors discussed above and as an additional
incentive for the future, Mr. Vincent was granted a significant number of stock
options in late 1995.
 
IMPACT OF INTERNAL REVENUE CODE SECTION 162(M)
 
     Internal Revenue Code Section 162(m) ("Section 162(m)") precludes a public
corporation from taking a deduction for compensation in excess of $1 million
paid to its chief executive officer or any of its four other highest paid
officers. At such time as this provision would impact the Company, the Board and
Committees will assess the practical effect on executive compensation and
determine what action, if any, is appropriate.
 
                                       12
<PAGE>   17
                                                              Preliminary Proxy 
 
COMMITTEES' ROLES
 
        The stock option plans for senior executives are administered by the
Stock and Option Plan Administration Committee  (consisting in 1995 of Messrs.
Morley and Stevens) of the Board of Directors. Other compensation decisions for
senior executives are made by the Compensation and Management Resources
Committee or, in the case of the Chief Executive Officer, by the Board based on
recommendations from that Committee.
 
                                        James W. Stevens, Chairman, Compensation
                                           and Management Resources Committee
                                        Roger H. Morley
                                        Phillip A. Sharp
                                        James L. Vincent
 

                                TRADING REPORTS
 
        The Company's officers, directors and greater-than-ten-percent
stockholders are required to file reports of ownership and change of ownership
with the Securities and Exchange Commission under the Securities Exchange
Act of 1934. Based solely on information provided to the Company by the
individual directors, officers and ten percent stockholder, the Company believes
that, during the fiscal year ended December 31, 1995, all such parties complied
with all applicable filing requirements except for late reporting of the
following transactions: (i) transfer of 4,566 shares by Timothy Kish, Vice
President-Finance and Chief Financial Officer, (ii) sale of 7,000 shares by
Harold Buirkle, a Director, and (iii) sale of 20,000 shares by Kenneth Murray, a
Director.
 
                                      13
<PAGE>   18
                                                              Preliminary Proxy 
 
                               PERFORMANCE GRAPH
 
     The following graph compares the yearly percentage change in the Company's
cumulative total shareholder return on its Common Stock during a period
commencing on December 31, 1990 and ending December 31, 1995 (as measured by
dividing (i) the sum of (A) the cumulative amount of dividends for the
measurement period, assuming dividend reinvestment, and (B) the difference
between the Company's share price at the end and the beginning of the period; by
(ii) the share price at the beginning of the period) with the cumulative return
of the Standard & Poor's 500 Stock Index and the NASDAQ Pharmaceutical Stocks
Total Return Index. The NASDAQ Pharmaceutical Stocks Total Return Index, which
is calculated and supplied by NASDAQ, represents all companies trading on NASDAQ
under the Standard Industrial Classification (SIC) Code for pharmaceutical,
including biotechnology, companies. Biogen has not paid dividends, and no
dividends are included in the representation of the Company's performance. The
stock price performance on the graph below is not necessarily indicative of
future price performance.
 
<TABLE>
<CAPTION>                                              NASDAQ
      Measurement Period                           Pharmaceutical
    (Fiscal Year Covered)                 BIOGEN       Index      S&P 500
<S>                                        <C>          <C>         <C>   
1990                                       100          100         100
1991                                       138          265         126
1992                                       162          221         132
1993                                       138          197         141
1994                                       144          148         139
1995                                       212          271         187
</TABLE>
 
                                       14
<PAGE>   19
                                                              Preliminary Proxy 
 
 
                     AMENDMENT TO INCREASE NUMBER OF SHARES
                           OF AUTHORIZED COMMON STOCK
 
     On February 16, 1996, the Board of Directors unanimously approved and
recommended to the stockholders an amendment to the Articles of Organization of
the Company to increase the number of shares of authorized Common Stock from
55,000,000 shares to 110,000,000 shares.
 
PURPOSE
 
     The principal purpose of the proposed amendment to the Articles of
Organization is to create a sufficient reserve of shares of Common Stock for
future needs of the Company. If the amendment is approved, the newly authorized
shares will be available for issuance by the Board of Directors, without further
stockholder approval, for any proper corporate purpose, which may include
payment of stock dividends, subdivision of outstanding shares through stock
splits, issuance of shares pursuant to any options, warrants or other rights
which may be issued in the future, issuance of shares in a public or private
offering or issuance of shares in a corporate acquisition or an acquisition of
property. The proposed amendment would give the Board of Directors the
flexibility to act promptly when it determines that issuance of additional
shares is in the best interest of the Company. The Company currently has no
arrangements or understandings with respect to the issuance of additional shares
other than for corporate transactions in the ordinary course of business and
pursuant to the Company's stock option and other employee benefit plans. As of
April 3, 1996,           shares of Common Stock were issued and outstanding and
an aggregate of           shares of Common Stock were reserved for issuance
under the Company's stock option and other employee benefit plans.
 
EFFECT
 
     Issuance of additional shares may have a dilutive effect on existing
stockholders. Under certain circumstances, issuance of additional shares may
also make it more difficult for a person to merge with or gain control of the
Company.
 
VOTE
 
     The affirmative vote of a majority of the outstanding shares entitled to
vote at the Meeting is required to approve an amendment to the Articles of
Organization. The Board of Directors believes that the amendment is advisable.
THE BOARD OF DIRECTORS RECOMMENDS APPROVAL OF THE AMENDMENT TO THE COMPANY'S
ARTICLES OF ORGANIZATION TO INCREASE THE NUMBER OF SHARES OF AUTHORIZED COMMON
STOCK FROM 55,000,000 SHARES TO 110,000,000 SHARES.
 
                                 MISCELLANEOUS
 
PROPOSALS OF STOCKHOLDERS
 
     To be included in the Company's 1997 Proxy Statement for consideration at
the Annual Meeting of Stockholders to be held in 1997, stockholder proposals
must be received by the Company, marked for the attention of the "Vice
President-General Counsel," not later than December 12, 1996.
 
                                       15
<PAGE>   20
                                                              Preliminary Proxy 
 
SOLICITATION AND VOTING OF PROXIES
 
     The proxy accompanying this Proxy Statement is solicited by the Board of
Directors of the Company. Directors, officers and other employees of the Company
may also solicit proxies by telephone, telegram, fax and personal solicitation.
No additional compensation will be paid to any Director, officer or employee for
such solicitation. The cost of soliciting proxies, including expenses in
connection with preparing and mailing this Proxy Statement, will be borne by the
Company. The Company will reimburse brokerage firms and other persons
representing beneficial owners of the Company's Common Stock for their expenses
in forwarding proxy material to such beneficial owners. The Company has hired
D.F. King & Co., Inc. to act as its proxy solicitation agent for the Meeting at
a cost of approximately $5,000.
 
     Stockholders of record on April 8, 1996, will be entitled to vote at the
meeting on the basis of one vote for each share held. If a stockholder specifies
a choice on the proxy as to how his or her shares are to be voted on a
particular matter, the shares will be voted accordingly. Unless authority to
vote for any of the proposals is withheld, the shares represented by the
enclosed proxy will be voted for such proposals. With respect to the matters to
be acted on at the Meeting, abstentions and broker non-votes will neither count
for nor against the proposal to be voted upon. For all proposals, abstentions
and broker non-votes will be counted toward determination of a quorum.
 
INCORPORATION BY REFERENCE
 
     Notwithstanding anything to the contrary set forth in any of the Company's
previous filings under the securities laws that might incorporate future
filings, including this Proxy Statement, in whole or in part, the reports of the
compensation and stock option committees and the performance graph included in
this Proxy Statement shall not be incorporated by reference into any such
filings.
 
OTHER MATTERS
 
     The Board of Directors knows of no other business which will be presented
to the Meeting. If other business is properly brought before the Meeting,
proxies in the enclosed form will be voted in accordance with the judgment of
the persons voting the proxies.
 
     WHETHER OR NOT YOU INTEND TO BE PRESENT AT THE MEETING, YOU ARE URGED TO
FILL OUT, SIGN, DATE AND RETURN THE ENCLOSED PROXY AT YOUR EARLIEST CONVENIENCE.
 
                                          By order of the Board of Directors:
 
                                          /s/ Michael J. Astrue
                                          ---------------------
                                          Michael J. Astrue
                                          Clerk
Cambridge, Massachusetts
April 12, 1996
 
                                       16
<PAGE>   21
                                                              Preliminary Proxy 
<TABLE>
                               CENTER DETAIL MAP
            FOR BIOGEN BUILDING LOCATIONS AND PARKING INSTRUCTIONS.
 
                                     [Map]
 
                             DIRECTIONS TO BIOGEN
<S>                                           <C>
     FROM LOGAN AIRPORT & BOSTON                      FROM NORTH OR SOUTH
Take Sumner Tunnel to Expressway (Rte.        Rte. 93 to Storrow Drive. Take Storrow
93). Go up ramp for 1/4 mile following        Drive to exit marked Kendall Square. Go
signs for Storrow Drive. Take Storrow         across Longfellow Bridge over Charles
Drive to left exit marked Kendall Square.     River and follow straight...
Go across Longfellow Bridge over Charles
River and follow straight. Marriott Hotel             FROM WALTHAM AND RTE. 2
will be 1 1/2 blocks down on left...          Rte. 2 to memorial Drive eastbound. (You
                                              will pass Harvard University, The B.U.
        FROM "T"                              Bridge, The Mass Ave. Bridge and MIT.) 
Take "T" to Kendall Square/MIT stop. Walk     After passing MIT, STAY TO THE RIGHT. Take
straight up stairs...                         left at lights (Kendall Square) onto
                                              Binney Street. Take left at 2nd light onto
                                              Third St. Proceed to end and turn right
                                              onto Broadway...
                                           
        FROM MASS AVE.,
left onto Ames Street at Legal Seafood...

        FROM WEST AND MASS PIKE
Take Mass Pike to exit 18 (Cambridge/
Allston/Brighton exit). After toll, bear
right (Cambridge/Somerville). Go straight
across Rive Street Bridge. Turn right onto
Memorial Drive eastbound. After passing
MIT, STAY TO THE RIGHT. Take left at first
set of lights (2nd Kendall Square sign)
onto Binney Street. Take left at 2nd light
onto Third Street. Proceed to end and turn
right onto Broadway...


</TABLE>

                   LOGO
 
 
  NOTE: UPON REACHING KENDALL SQUARE, PLEASE REFER TO KENDALL SQUARE CAMBRIDGE
<PAGE>   22
                                                              Preliminary Proxy 
 
                                     [LOGO]

                              12 CAMBRIDGE CENTER
                              CAMBRIDGE, MA 02142
 
                            NOTICE OF ANNUAL MEETING
                              AND PROXY STATEMENT
 
                                  MEETING DATE
                                  MAY 31, 1996
<PAGE>   23
                                                               Preliminary Proxy

                                 BIOGEN, INC.

                              PROXY SOLICITED BY
                    THE BOARD OF DIRECTORS OF BIOGEN, INC.
                    FOR THE ANNUAL MEETING OF STOCKHOLDERS
                          TO BE HELD ON MAY 31, 1996
                                      
        The undersigned hereby acknowledges receipt of the Notice of Annual
Meeting of Stockholders and Proxy Statement, dated April 12, 1996, and does
hereby appoint James L. Vincent and Michael J. Astrue, and each of them,
proxies of the undersigned with all the powers the undersigned would possess 
if personally present and with full power of substitution in each of them, to
appear and vote all shares of Common Stock of Biogen, Inc., a Massachusetts
corporation, which the undersigned would be entitled to vote if personally
present at the Annual Meeting of Stockholders to be held on Friday, May 31,
1996 at 10:00 a.m. at the Company's offices located at 12 Cambridge Center, 
Cambridge, MA  02142.

        The shares represented hereby will be voted as directed herein.  IN
EACH CASE IF NO DIRECTION IS INDICATED, SUCH SHARES WILL BE VOTED FOR THE
ELECTION OF THE NAMED NOMINEES AS DIRECTORS AND FOR PROPOSALS 2 AND 3 BELOW. 
AS TO ANY OTHER MATTER, SAID PROXY HOLDERS WILL VOTE IN ACCORDANCE WITH THEIR
BEST JUDGMENT.  THIS PROXY MAY BE REVOKED IN WRITING AT ANY TIME PRIOR TO THE
VOTING THEREOF.

In their discretion, the proxies are also authorized to vote upon such other
matters as may properly come before the meeting.

Please vote, date and sign on other side and return promptly in enclosed
envelope.

Please sign this proxy exactly as your name appears on the reverse side. Joint
owners should each sign personally. Trustees and other fiduciaries should
indicate the capacity in which they sign and where more than one name appears,
a majority must sign. If a Corporation, this signature should be that of an
authorized officer who should state his or her title.

Has your address changed?                  Do you have any comments?

- ----------------------------------         ------------------------------------

                                 [Reverse Side]

Please mark votes as in this example /x/

Biogen Inc.

Record date shares:


1. ELECTION OF DIRECTORS

/ / FOR nominees listed below          / / WITHHOLD         / / FOR all except


NOMINEES: Roger H. Morley, Phillip A. Sharp and James R. Tobin for a three year
term ending at the Annual Meeting of Stockholders in 1999 and until their
successors are duly elected and qualified or their earlier resignation or 
removal. 

Roger H. Morley, Phillip A. Sharp and James C. Tobin. 

If you do not wish your shares voted "FOR" a particular nominee, mark the 
"FOR ALL EXCEPT" box and strike a line through the nominee's name. Your shares 
will be voted for the remaining nominees.

<PAGE>   24
                                                               Preliminary Proxy

2. To ratify the selection by the Company's Board of Directors of Price
Waterhouse LLP as the Company's independent accountants for the fiscal year
ending December 31, 1996.

        / / FOR                 / / AGAINST             / / ABSTAIN

3. To approve an amendment to the Company's Articles of Organization to increase
the number of authorized shares of Common Stock from 55,000,000 shares to
110,000,000 shares.

        / / FOR                 / / AGAINST             / / ABSTAIN


Mark box at right if comments or address change have been noted on the reverse
side of the card. / / 


                                Date:                           , 1996
                                     ---------------------------

Please be sure to sign
and date this Proxy
                                --------------------------------------
                                                Signature


                                --------------------------------------
                                                Signature


Dear Stockholder:

Please take note of the important information enclosed with this Proxy Ballot.
There are a number of issues related to the management and operation of your
company that require your immediate attention and approval. These are discussed
in detail in the enclosed proxy materials.

Your vote counts, and you are strongly encouraged to exercise your right to
vote your shares.

Please mark the boxes on the proxy card to indicate how your shares shall be
voted, then sign the card, detach it and return your proxy vote in the enclosed
envelope.

Your vote must be received prior to the Annual Meeting of Stockholders, 
May 31, 1996. 

Thank you in advance for your prompt consideration of these matters.

Sincerely,

Biogen, Inc.



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