<PAGE> 1
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
---------------
Form 10-C
REPORT BY ISSUER OF SECURITIES QUOTED ON NASDAQ
INTERDEALER QUOTATION SYSTEM
FILED PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
AND RULE 13a-17 OR 15d-17 THEREUNDER
CYPRESS BIOSCIENCE, INC.
(Exact name of issuer as specified in its charter)
401 Queen Anne Avenue North, Seattle, WA 98109
(Address of Principal Executive Offices)
(206) 298-9400
(Issuer's telephone number including area code)
I. CHANGE IN NUMBER OF SHARES OUTSTANDING
Indicate any change (increase or decrease) of 5% or more in the number of
shares outstanding:
1. Title of Security
------------------------------------------------------
2. Number of shares outstanding before the change
-------------------------
3. Number of shares outstanding after the change
--------------------------
4. Effective date of change: September 1, 1995
---------------------------
5. Method of change:
Specify method (such as merger, acquisition, exchange, distribution,
stock split, reverse split, acquisition of stock for treasury
etc.)
------------------------------------------------------------------
Give brief description of transaction
------------------------------------------
- -------------------------------------------------------------------------------
II. CHANGE IN NAME OF ISSUER
1. Name prior to change IMRE CORPORATION
---------------------------------------------------
2. Name after change CYPRESS BIOSCIENCE, INC.
------------------------------------------------------
3. Effective date of charter amendment changing name April 18, 1996
----------------------
4. Date of shareholder approval of change, if required April 15, 1996
--------------------
Dated: April 25, 1996 /s/ SUSAN E. FEINER
-------------------------------------
Susan E. Feiner
Controller, Secretary and Treasurer