IMRE CORP
10-C, 1996-04-25
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1

                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                               ---------------

                                  Form 10-C

               REPORT BY ISSUER OF SECURITIES QUOTED ON NASDAQ
                         INTERDEALER QUOTATION SYSTEM

  FILED PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
                     AND RULE 13a-17 OR 15d-17 THEREUNDER

                           CYPRESS BIOSCIENCE, INC.
            (Exact name of issuer as specified in its charter)

                 401 Queen Anne Avenue North, Seattle, WA 98109
                   (Address of Principal Executive Offices)

                                 (206) 298-9400
               (Issuer's telephone number including area code)

                   I. CHANGE IN NUMBER OF SHARES OUTSTANDING

Indicate any change (increase or decrease) of 5% or more in the number of
shares outstanding:

1.      Title of Security
                         ------------------------------------------------------

2.      Number of shares outstanding before the change
                                                      -------------------------
3.      Number of shares outstanding after the change
                                                     -------------------------- 
4.      Effective date of change:  September 1, 1995
                                                    ---------------------------
5.      Method of change:
        Specify method (such as merger, acquisition, exchange, distribution,
        stock split, reverse split, acquisition of stock for treasury
        etc.)
             ------------------------------------------------------------------

Give brief description of transaction
                                     ------------------------------------------

- -------------------------------------------------------------------------------


                         II. CHANGE IN NAME OF ISSUER


1.      Name prior to change  IMRE CORPORATION
                            ---------------------------------------------------
2.      Name after change  CYPRESS BIOSCIENCE, INC.
                         ------------------------------------------------------
3.      Effective date of charter amendment changing name  April 18, 1996
                                                         ----------------------
4.      Date of shareholder approval of change, if required  April 15, 1996
                                                           --------------------


Dated: April 25, 1996                     /s/ SUSAN E. FEINER
                                          -------------------------------------
                                          Susan E. Feiner
                                          Controller, Secretary and Treasurer



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